Result of FASTA (omim) for
pFN21AE9605
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9605, 221 aa
1>>>pF1KE9605 221 - 221 aa - 221 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7745+/-0.000397; mu= 0.0861+/- 0.025
mean_var=242.8610+/-48.113, 0's: 0 Z-trim(120.1): 42 B-trim: 0 in 0/58
Lambda= 0.082299
statistics sampled from 34873 (34915) to 34873 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.715), E-opt: 0.2 (0.409), width: 16
Scan time: 7.120
The best scores are: opt bits E(85289)
NP_005311 (OMIM: 142210) histone H1.3 [Homo sapien ( 221) 1362 173.8 2e-43
NP_005312 (OMIM: 142220) histone H1.4 [Homo sapien ( 219) 1142 147.7 1.5e-35
NP_005310 (OMIM: 142710) histone H1.2 [Homo sapien ( 213) 1053 137.1 2.2e-32
NP_005313 (OMIM: 142711) histone H1.5 [Homo sapien ( 226) 1020 133.2 3.5e-31
NP_005316 (OMIM: 142709) histone H1.1 [Homo sapien ( 215) 827 110.2 2.6e-24
NP_005314 (OMIM: 142712) histone H1t [Homo sapiens ( 207) 508 72.4 6.5e-13
NP_005309 (OMIM: 142708) histone H1.0 [Homo sapien ( 194) 359 54.6 1.3e-07
NP_006017 (OMIM: 602785) histone H1x [Homo sapiens ( 213) 298 47.4 2.1e-05
>>NP_005311 (OMIM: 142210) histone H1.3 [Homo sapiens] (221 aa)
initn: 1362 init1: 1362 opt: 1362 Z-score: 900.5 bits: 173.8 E(85289): 2e-43
Smith-Waterman score: 1362; 100.0% identity (100.0% similar) in 221 aa overlap (1-221:1-221)
10 20 30 40 50 60
pF1KE9 MSETAPLAPTIPAPAEKTPVKKKAKKAGATAGKRKASGPPVSELITKAVAASKERSGVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSETAPLAPTIPAPAEKTPVKKKAKKAGATAGKRKASGPPVSELITKAVAASKERSGVSL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGKPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGKPK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 AKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKKVKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKKVKT
130 140 150 160 170 180
190 200 210 220
pF1KE9 PQPKKAAKSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKKK
:::::::::::::::::::::::::::::::::::::::::
NP_005 PQPKKAAKSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKKK
190 200 210 220
>>NP_005312 (OMIM: 142220) histone H1.4 [Homo sapiens] (219 aa)
initn: 814 init1: 814 opt: 1142 Z-score: 759.4 bits: 147.7 E(85289): 1.5e-35
Smith-Waterman score: 1142; 86.0% identity (94.1% similar) in 221 aa overlap (1-221:1-219)
10 20 30 40 50 60
pF1KE9 MSETAPLAPTIPAPAEKTPVKKKAKKAGATAGKRKASGPPVSELITKAVAASKERSGVSL
:::::: ::. :::::::::::::.:. : :.::::::::::::::::::::::::::::
NP_005 MSETAPAAPAAPAPAEKTPVKKKARKS-AGAAKRKASGPPVSELITKAVAASKERSGVSL
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGKPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::
NP_005 AALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE9 AKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKKVKT
:::::::: .:::::::::::..:::::::: ::::::.::::.:::.:: ::: ::.:.
NP_005 AKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKK-AKSPKKAKA
120 130 140 150 160 170
190 200 210 220
pF1KE9 PQPKKAAKSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKKK
.:::: :::::::: ::::::::..:::..: :::: :::
NP_005 AKPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK
180 190 200 210
>>NP_005310 (OMIM: 142710) histone H1.2 [Homo sapiens] (213 aa)
initn: 1065 init1: 882 opt: 1053 Z-score: 702.4 bits: 137.1 E(85289): 2.2e-32
Smith-Waterman score: 1053; 81.1% identity (90.5% similar) in 222 aa overlap (1-221:1-213)
10 20 30 40 50
pF1KE9 MSETAPLAPTIPAPAEKTPVKKKA-KKAGATAGKRKASGPPVSELITKAVAASKERSGVS
:::::: ::. ::::.:::::: ::::.: ::::::::::::::::::::::::::
NP_005 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGT--PRKASGPPVSELITKAVAASKERSGVS
10 20 30 40 50
60 70 80 90 100 110
pF1KE9 LAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGKP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_005 LAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE9 KAKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKKVK
:.::::..::.::.::::::::.::.:::::: ::::::.::::.:. ::::::: ::.:
NP_005 KVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAK
120 130 140 150 160 170
180 190 200 210 220
pF1KE9 TPQPKKAAKSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKKK
. .::::::: ::: .:::..::::.: ::::::::
NP_005 VAKPKKAAKSAAKA-------VKPKAAKPKVVKPKKAAPKKK
180 190 200 210
>>NP_005313 (OMIM: 142711) histone H1.5 [Homo sapiens] (226 aa)
initn: 682 init1: 682 opt: 1020 Z-score: 680.9 bits: 133.2 E(85289): 3.5e-31
Smith-Waterman score: 1020; 78.3% identity (89.1% similar) in 230 aa overlap (1-221:1-226)
10 20 30 40 50
pF1KE9 MSETAPLAPTIPAPAEKTPVKKKAKK--AGATAGKRKASGPPVSELITKAVAASKERSGV
:::::: . :::.::.:.:::: : ::: :.::::.::::::::::::::::::.:.
NP_005 MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGK
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::.:
NP_005 SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 PKAKKAGAAKPRKPAGAA-KKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKK
:::::::::: .:::::. :: ::.::: ::..::::::.:::: :::.:::::: ::
NP_005 PKAKKAGAAKAKKPAGATPKKAKKAAGA---KKAVKKTPKKAKKPA-AAGVKKVAKSPKK
130 140 150 160 170
180 190 200 210 220
pF1KE9 VKTP-QPKKAAKSPAKAKA--PK---PKAAKPKSGKPKVTKAKKAAPKKK
.:. .::::.::::: :: :: :::::::..:::..:::::: :::
NP_005 AKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK
180 190 200 210 220
>>NP_005316 (OMIM: 142709) histone H1.1 [Homo sapiens] (215 aa)
initn: 501 init1: 501 opt: 827 Z-score: 557.3 bits: 110.2 E(85289): 2.6e-24
Smith-Waterman score: 827; 67.7% identity (83.0% similar) in 223 aa overlap (1-221:1-215)
10 20 30 40 50
pF1KE9 MSETAPLAPTIPAPAEKTPVKKKAKKAG--ATAGKRKASGPPVSELITKAVAASKERSGV
::::.: ::. : :: . ::::: . :.:.:.: .:: :::::..:...::::.::
NP_005 MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGK
::::::::::::::::::::::::::.:::::::::::::::::::::::::::.: : :
NP_005 SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 PKAKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKKV
: :.:. : : .::.:: ::..::. :::.: ::::.::: :.:.: .:. ::
NP_005 PGASKV--ATKTKATGASKKLKKATGAS--KKSVK-TPKKAKKP---AATRKSSKNPKKP
130 140 150 160 170
180 190 200 210 220
pF1KE9 KTPQPKKAAKSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKKK
:: .:::.::::::::: :::::: . :::..: ::::::::
NP_005 KTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK
180 190 200 210
>>NP_005314 (OMIM: 142712) histone H1t [Homo sapiens] (207 aa)
initn: 518 init1: 405 opt: 508 Z-score: 352.9 bits: 72.4 E(85289): 6.5e-13
Smith-Waterman score: 535; 49.1% identity (73.4% similar) in 218 aa overlap (1-215:1-207)
10 20 30 40 50
pF1KE9 MSETAPLAPTIP--APAEKTPVKKKAKK-AGATAGKRKASGPPVSELITKAVAASKERSG
::::.: : . : :: :.::...: :: ...::. . ::.:::.:...:.:: :
NP_005 MSETVPAASASAGVAAMEKLPTKKRGRKPAGLISASRKVPNLSVSKLITEALSVSQERVG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE9 VSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEG
.::.::::::::::::::::::::::.:::::.:: ::::.::::::::::.::.
NP_005 MSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKST
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE9 KPKAKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKK
. ::::. .:: .: . .. .: .:: . :: :..::: : : :...:..:
NP_005 RSKAKKSVSAKTKKL--VLSRDSK-----SPKTA--KTNKRAKKP--RATTPKTVRSGRK
130 140 150 160
180 190 200 210 220
pF1KE9 VKTPQPKKAAKSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKKK
.: . :. :::.::.: : : .. . . . . .::
NP_005 AKGAKGKQQQKSPVKARASKSKLTQHHEVNVRKATSKK
170 180 190 200
>>NP_005309 (OMIM: 142708) histone H1.0 [Homo sapiens] (194 aa)
initn: 349 init1: 175 opt: 359 Z-score: 257.6 bits: 54.6 E(85289): 1.3e-07
Smith-Waterman score: 368; 39.9% identity (63.9% similar) in 208 aa overlap (16-221:3-194)
10 20 30 40 50 60
pF1KE9 MSETAPLAPTIPAPAEKTPVKKKAKKAGATAGKRKASGPPVSELITKAVAASKERSGVSL
:.. :: : :.:.... : :..:. :. : :.:.: :
NP_005 MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSR
10 20 30 40
70 80 90 100 110
pF1KE9 AALKKALAAAGYDVEKN-NSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGKP
...: . . : : .: .:.:::..: ::. :.: ::::.::::::.: :. .:
NP_005 QSIQKYIKSH-YKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKS-----DEP
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE9 KAKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTP-KKVKKPATAAGTKKVAKSAKKV
: :... : .: . ::: :. :::. .:.: :: : . . ::.: . ::.
NP_005 K-KSVAFKKTKKEIKKVATPKK---ASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKA
110 120 130 140 150
180 190 200 210 220
pF1KE9 KTPQPKKAAKSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKKK
: :. :: .:.::. ::: ::: :::. .. : : :::
NP_005 KKPKTVKA--KPVKAS--KPKKAKPV--KPKAKSSAKRAGKKK
160 170 180 190
>>NP_006017 (OMIM: 602785) histone H1x [Homo sapiens] (213 aa)
initn: 485 init1: 168 opt: 298 Z-score: 217.9 bits: 47.4 E(85289): 2.1e-05
Smith-Waterman score: 314; 35.4% identity (63.2% similar) in 223 aa overlap (4-215:2-213)
10 20 30 40 50
pF1KE9 MSETAPLAPTIPAPAEKTPVKKKAKKAGATAG-----KRKAS---GPP--VSELITKAVA
.. : ..:. . . . ::. :::..:. ::: : . : :.:.....
NP_006 MSVELEEALPVTTAEG-MAKKVTKAGGSAALSPSKKRKNSKKKNQPGKYSQLVVETIR
10 20 30 40 50
60 70 80 90 100
pF1KE9 ASKERSGVSLAAL-KKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLN
::.: ::: . .: . .: ... . .: ..:.::.. ::.:.:::::.::::::
NP_006 RLGERNGSSLAKIYTEAKKVPWFDQQNGRTYLKYSIKALVQNDTLLQVKGTGANGSFKLN
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE9 KKAASGEGKPKAKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTPKKVKKPATAAGTK
.: : :. .. :.:. :: .:.: ::.: .:. .. : : . .:: ..
NP_006 RKKLEGGGERRGAPAAATA---PAPTAHKAKKAAPGAAGSRRADKKPARGQKPEQR--SH
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE9 KVAKSAKKVKTPQPKKAAKSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKKK
: . .::: : . ::.: : .: : :::::. ::: :..:
NP_006 KKGAGAKKDKGGKAKKTAA--AGGKKVK-KAAKPSV--PKVPKGRK
180 190 200 210
221 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 06:27:39 2016 done: Sun Nov 6 06:27:40 2016
Total Scan time: 7.120 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]