Result of FASTA (omim) for
pFN21AE1218
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1218, 213 aa
1>>>pF1KE1218 213 - 213 aa - 213 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.4782+/-0.000352; mu= 1.0783+/- 0.022
mean_var=205.0416+/-40.915, 0's: 0 Z-trim(120.9): 35 B-trim: 152 in 1/58
Lambda= 0.089568
statistics sampled from 36769 (36806) to 36769 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.732), E-opt: 0.2 (0.432), width: 16
Scan time: 6.280
The best scores are: opt bits E(85289)
NP_005310 (OMIM: 142710) histone H1.2 [Homo sapien ( 213) 1308 180.5 1.8e-45
NP_005312 (OMIM: 142220) histone H1.4 [Homo sapien ( 219) 1106 154.4 1.3e-37
NP_005311 (OMIM: 142210) histone H1.3 [Homo sapien ( 221) 1053 147.6 1.5e-35
NP_005313 (OMIM: 142711) histone H1.5 [Homo sapien ( 226) 978 137.9 1.3e-32
NP_005316 (OMIM: 142709) histone H1.1 [Homo sapien ( 215) 799 114.8 1.1e-25
NP_005314 (OMIM: 142712) histone H1t [Homo sapiens ( 207) 524 79.2 5.4e-15
NP_005309 (OMIM: 142708) histone H1.0 [Homo sapien ( 194) 373 59.7 3.8e-09
NP_006017 (OMIM: 602785) histone H1x [Homo sapiens ( 213) 335 54.8 1.2e-07
>>NP_005310 (OMIM: 142710) histone H1.2 [Homo sapiens] (213 aa)
initn: 1308 init1: 1308 opt: 1308 Z-score: 937.5 bits: 180.5 E(85289): 1.8e-45
Smith-Waterman score: 1308; 100.0% identity (100.0% similar) in 213 aa overlap (1-213:1-213)
10 20 30 40 50 60
pF1KE1 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA
130 140 150 160 170 180
190 200 210
pF1KE1 KPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK
:::::::::::::::::::::::::::::::::
NP_005 KPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK
190 200 210
>>NP_005312 (OMIM: 142220) histone H1.4 [Homo sapiens] (219 aa)
initn: 931 init1: 931 opt: 1106 Z-score: 796.3 bits: 154.4 E(85289): 1.3e-37
Smith-Waterman score: 1106; 86.9% identity (93.9% similar) in 214 aa overlap (1-212:1-213)
10 20 30 40 50 60
pF1KE1 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA
::::::::::: ::::.:::::: :.::.. ::::::::::::::::::::::::::::
NP_005 MSETAPAAPAAPAPAEKTPVKKKARKSAGAAKRKASGPPVSELITKAVAASKERSGVSLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_005 ALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPKA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 KKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAKVA
::::..: :::.:::::::::.:.::::::::::::::::::::. .:: ::::::::.:
NP_005 KKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKK-AKSPKKAKAA
130 140 150 160 170
190 200 210
pF1KE1 KPKKAAKSAAKA--VKPKAAKPKVVKPKKAAPKKK
::::: :: ::: :::::::::..::: : :::
NP_005 KPKKAPKSPAKAKAVKPKAAKPKTAKPKAAKPKKAAAKKK
180 190 200 210
>>NP_005311 (OMIM: 142210) histone H1.3 [Homo sapiens] (221 aa)
initn: 1231 init1: 882 opt: 1053 Z-score: 759.2 bits: 147.6 E(85289): 1.5e-35
Smith-Waterman score: 1053; 81.1% identity (90.5% similar) in 222 aa overlap (1-213:1-221)
10 20 30 40 50
pF1KE1 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTP--RKASGPPVSELITKAVAASKERSGVS
:::::: ::. ::::.:::::: ::::.: ::::::::::::::::::::::::::
NP_005 MSETAPLAPTIPAPAEKTPVKKKA-KKAGATAGKRKASGPPVSELITKAVAASKERSGVS
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 LAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::
NP_005 LAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGKP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE1 KVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKAK
:.::::..::.::.::::::::.::.:::::: ::::::.::::.:. ::::::: ::.:
NP_005 KAKKAGAAKPRKPAGAAKKPKKVAGAATPKKSIKKTPKKVKKPATAAGTKKVAKSAKKVK
120 130 140 150 160 170
180 190 200 210
pF1KE1 VAKPKKAAKSAAKA-------VKPKAAKPKVVKPKKAAPKKK
. .::::::: ::: .:::..::::.: ::::::::
NP_005 TPQPKKAAKSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKKK
180 190 200 210 220
>>NP_005313 (OMIM: 142711) histone H1.5 [Homo sapiens] (226 aa)
initn: 737 init1: 737 opt: 978 Z-score: 706.7 bits: 137.9 E(85289): 1.3e-32
Smith-Waterman score: 978; 79.4% identity (89.9% similar) in 218 aa overlap (1-211:1-214)
10 20 30 40 50
pF1KE1 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGT---PRKASGPPVSELITKAVAASKERSGV
::::::: :. :.::.:.::::.:::.:. :::.::::::::::::::::::.:.
NP_005 MSETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATGPPVSELITKAVAASKERNGL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SLAALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 PKVKKAGGTKPKKPVGAA-KKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKK
::.::::..: :::.::. :: :::::. ::..::::::::::::: : :::::::::
NP_005 PKAKKAGAAKAKKPAGATPKKAKKAAGA---KKAVKKTPKKAKKPAAAGV-KKVAKSPKK
130 140 150 160 170
180 190 200 210
pF1KE1 AKVA-KPKKAAKSAAK--AVKPKAAKPKVVKPKKAAPKKK
::.: :::::.:: :: ::::::::::..::: : ::
NP_005 AKAAAKPKKATKSPAKPKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKKK
180 190 200 210 220
>>NP_005316 (OMIM: 142709) histone H1.1 [Homo sapiens] (215 aa)
initn: 585 init1: 511 opt: 799 Z-score: 582.0 bits: 114.8 E(85289): 1.1e-25
Smith-Waterman score: 799; 67.7% identity (83.4% similar) in 223 aa overlap (1-213:1-215)
10 20 30 40 50
pF1KE1 MSETAPAAPAAAPPAEKAPVKKKA---AKKAGGTPRKASGPPVSELITKAVAASKERSGV
::::.: ::::. :: . ::: :: :... .: .:: :::::..:...::::.::
NP_005 MSETVPPAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 SLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAK
::::::::::::::::::::::::::.:::::::::::::::::::::::::::.: :.:
NP_005 SLAALKKALAAAGYDVEKNNSRIKLGIKSLVSKGTLVQTKGTGASGSFKLNKKASSVETK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 PKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSPKKA
: ..:.. :: : .::.:: :::.:.. :::.: :::::::::: :.: .:.:::
NP_005 PGASKVA-TKTKA-TGASKKLKKATGAS--KKSVK-TPKKAKKPAA---TRKSSKNPKKP
130 140 150 160 170
180 190 200 210
pF1KE1 KVAKPKKAAKSAAKA--VKPKAAK-----PKVVKPKKAAPKKK
:..::::.::: ::: ::::::: ::..::::::::::
NP_005 KTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKAAPKKK
180 190 200 210
>>NP_005314 (OMIM: 142712) histone H1t [Homo sapiens] (207 aa)
initn: 531 init1: 379 opt: 524 Z-score: 390.2 bits: 79.2 E(85289): 5.4e-15
Smith-Waterman score: 553; 52.7% identity (73.2% similar) in 220 aa overlap (1-212:1-207)
10 20 30 40 50
pF1KE1 MSETAPAAPAAAPPA--EKAPVKKKAAKKAG--GTPRKASGPPVSELITKAVAASKERSG
::::.::: :.: : :: :.::.. : :: .. ::. . ::.:::.:...:.:: :
NP_005 MSETVPAASASAGVAAMEKLPTKKRGRKPAGLISASRKVPNLSVSKLITEALSVSQERVG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 VSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEA
.::.::::::::::::::::::::::.:::::.:: ::::.::::::::::.::. .
NP_005 MSLVALKKALAAAGYDVEKNNSRIKLSLKSLVNKGILVQTRGTGASGSFKLSKKVIPKST
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 KPKVKKAGGTKPKKPVGA--AKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAKSP
. :.::. ..: :: : . .:.:: : :: :.:::: :.: :...:
NP_005 RSKAKKSVSAKTKKLVLSRDSKSPKTA-----------KTNKRAKKPRATT--PKTVRSG
130 140 150 160
180 190 200 210
pF1KE1 KKAKVAKPKKAAKSA--AKAVKPKAAKPKVVKPKKAAPKKK
.::: :: :. :: :.: : : .. . :. .::. ::
NP_005 RKAKGAKGKQQQKSPVKARASKSKLTQHHEVNVRKATSKK
170 180 190 200
>>NP_005309 (OMIM: 142708) histone H1.0 [Homo sapiens] (194 aa)
initn: 433 init1: 210 opt: 373 Z-score: 285.1 bits: 59.7 E(85289): 3.8e-09
Smith-Waterman score: 398; 42.4% identity (63.6% similar) in 217 aa overlap (1-213:1-189)
10 20 30 40 50 60
pF1KE1 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLA
:.:.. .:::: : . ::.::. :. :..:. :. : :.:.: :
NP_005 MTENSTSAPAAKPK------RAKASKKSTDHPK------YSDMIVAAIQAEKNRAGSSRQ
10 20 30 40
70 80 90 100 110
pF1KE1 ALKKALAAAGYDVEKN-NSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK
...: . . : : .: .:.:::..: ::. :.: ::::.::::::.: : : : ::
NP_005 SIQKYIKSH-YKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAK---SDE--PK
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE1 VKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTK---KVAKSPKK
:... : :: . . ::::. :::.:.:.: .::: :. : : :.: .:::
NP_005 -KSVAFKKTKKEIKKVATPKKAS---KPKKAASKAP--TKKPKATPVKKAKKKLAATPKK
110 120 130 140 150
180 190 200 210
pF1KE1 AKVAKPKKAAKSAAKAVKPKAAKPKVVKPKKAAPKKK
:: ::: . . .:: ::: ::: :::: . :.
NP_005 AK--KPKTVKAKPVKASKPKKAKP--VKPKAKSSAKRAGKKK
160 170 180 190
>>NP_006017 (OMIM: 602785) histone H1x [Homo sapiens] (213 aa)
initn: 370 init1: 172 opt: 335 Z-score: 258.0 bits: 54.8 E(85289): 1.2e-07
Smith-Waterman score: 335; 37.3% identity (63.7% similar) in 204 aa overlap (5-206:18-210)
10 20 30 40
pF1KE1 MSETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKA
: . :. : .: ::. .: . : : :.:....
NP_006 MSVELEEALPVTTAEGMAKKVTKAGGSAALSPSKKRKNSKKKNQPGK-----YSQLVVET
10 20 30 40 50
50 60 70 80 90 100
pF1KE1 VAASKERSGVSLAAL-KKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFK
. ::.: ::: . .: . .: ... . .: ..:.::.. ::.:.:::::.::::
NP_006 IRRLGERNGSSLAKIYTEAKKVPWFDQQNGRTYLKYSIKALVQNDTLLQVKGTGANGSFK
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE1 LNKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATV
::.: : .. . :..: : : .:.: :::: ::. .. : : : ...:: .
NP_006 LNRKKLEGGGERRGAPAAATAPA-P--TAHKAKKAAPGAAGSRRADKKPARGQKPEQRS-
120 130 140 150 160 170
170 180 190 200 210
pF1KE1 TKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAKPKVVK-PKKAAPKKK
.: . . :: : .: ::.: ...: :: :::::.: : ::
NP_006 -HKKGAGAKKDKGGKAKKTAAAGGKKVK-KAAKPSVPKVPKGRK
180 190 200 210
213 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 11 16:59:36 2016 done: Fri Nov 11 16:59:37 2016
Total Scan time: 6.280 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]