Result of FASTA (ccds) for
pFN21AB9595
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9595, 553 aa
1>>>pF1KB9595 553 - 553 aa - 553 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.8052+/-0.00103; mu= -11.6038+/- 0.063
mean_var=529.6616+/-110.783, 0's: 0 Z-trim(117.9): 75 B-trim: 212 in 1/53
Lambda= 0.055728
statistics sampled from 18634 (18709) to 18634 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.818), E-opt: 0.2 (0.575), width: 16
Scan time: 4.620
The best scores are: opt bits E(32554)
CCDS4473.1 FOXC1 gene_id:2296|Hs108|chr6 ( 553) 3820 321.4 1.8e-87
CCDS10958.1 FOXC2 gene_id:2303|Hs108|chr16 ( 501) 1171 108.4 2.1e-23
CCDS13192.1 FOXS1 gene_id:2307|Hs108|chr20 ( 330) 655 66.7 4.8e-11
CCDS75259.1 FOXD1 gene_id:2297|Hs108|chr5 ( 465) 649 66.4 8.6e-11
>>CCDS4473.1 FOXC1 gene_id:2296|Hs108|chr6 (553 aa)
initn: 3820 init1: 3820 opt: 3820 Z-score: 1684.1 bits: 321.4 E(32554): 1.8e-87
Smith-Waterman score: 3820; 100.0% identity (100.0% similar) in 553 aa overlap (1-553:1-553)
10 20 30 40 50 60
pF1KB9 MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 ARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 ARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 GWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 KDKEEKDRLHLKEPPPPGRQPPPAPPEQADGNAPGPQPPPVRIQDIKTENGTCPSPPQPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 KDKEEKDRLHLKEPPPPGRQPPPAPPEQADGNAPGPQPPPVRIQDIKTENGTCPSPPQPL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 SPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPPPPAPSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 SPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPPPPAPSAP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 PPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 PPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 YSSPCSQTSSAGSSGGGGGGAGAAGGAGGAGTYHCNLQAMSLYAAGERGGHLQGAPGGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 YSSPCSQTSSAGSSGGGGGGAGAAGGAGGAGTYHCNLQAMSLYAAGERGGHLQGAPGGAG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 GSAVDDPLPDYSLPPVTSSSSSSLSHGGGGGGGGGGQEAGHHPAAHQGRLTSWYLNQAGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GSAVDDPLPDYSLPPVTSSSSSSLSHGGGGGGGGGGQEAGHHPAAHQGRLTSWYLNQAGG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 DLGHLASAAAAAAAAGYPGQQQNFHSVREMFESQRIGLNNSPVNGNSSCQMAFPSSQSLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 DLGHLASAAAAAAAAGYPGQQQNFHSVREMFESQRIGLNNSPVNGNSSCQMAFPSSQSLY
490 500 510 520 530 540
550
pF1KB9 RTSGAFVYDCSKF
:::::::::::::
CCDS44 RTSGAFVYDCSKF
550
>>CCDS10958.1 FOXC2 gene_id:2303|Hs108|chr16 (501 aa)
initn: 1177 init1: 813 opt: 1171 Z-score: 533.6 bits: 108.4 E(32554): 2.1e-23
Smith-Waterman score: 1524; 49.9% identity (66.8% similar) in 587 aa overlap (1-553:1-501)
10 20 30 40 50 60
pF1KB9 MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGM
::::::::.::.:::::::. ::.::::: :.: .: .::.::: .: ::: .::
CCDS10 MQARYSVSDPNALGVVPYLS-EQNYYRAA-----GSYGGMASPMGVYS--GHPEQYSAGM
10 20 30 40 50
70 80 90 100 110
pF1KB9 ARAYGPYTP-QPQ-PKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDN
.:.:.:: :: :::.:::::::::::::::::::.::::::::::::::::::::.:
CCDS10 GRSYAPYHHHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYREN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 KQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 KQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKD
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 AVKDKEEKDRLHLKEPPPPGRQPPPAPPEQADGNAPGPQPPPVRIQDIKTENGTCPSPP-
. :.::: : ::::::: . . :: :. ::. :. .. ::.: .. :. :
CCDS10 VSKEKEE--RAHLKEPPPAASKGAPATPHLADA----PKEAEKKVV-IKSEAAS-PALPV
180 190 200 210 220
240 250 260 270 280 290
pF1KB9 ----QPLSPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPP
. ::: .:: .:: :. :..: .:: : :::: .
CCDS10 ITKVETLSPESAL-QGS----PR------SAASTPAGS-PDGSLPEHH------------
230 240 250 260
300 310 320 330 340 350
pF1KB9 PPAPSAPPPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAG-IAPPLALGA
::.. : ::::.:::: :: :: .. ::: : ..::: ..:::::
CCDS10 AAAPNGLP-----GFSVENIMT-LRTSPPGG--ELSPG-------AGRAGLVVPPLAL-P
270 280 290 300
360 370 380 390 400 410
pF1KB9 YSPGQSSLYSSPCSQTSSAGSSGGGGGGAGAAGGAGGAGTYHCNLQAMSLYAAGERGGHL
:. . . :..::.: : :::::: :.:...:::::...:: .:.
CCDS10 YAAAPPAAYGQPCAQ----------GLEAGAAGG------YQCSMRAMSLYTGAERPAHM
310 320 330 340
420 430 440 450 460
pF1KB9 QGAPGGAGGSAVDDPLPDYSLPPVTSSSSSSLSHGGGGGGGGGG---QEAGHH-------
: :.:. : :. :.. :. .:. : :. .. : :. :::
CCDS10 CVPP------ALDEALSDHPSGPTSPLSALNLAAGQEGALAATGHHHQHHGHHHPQAPPP
350 360 370 380 390 400
470 480 490 500 510
pF1KB9 -----------PAAHQGRLTSWYLNQAGGDLGHLASAAAAAAAAGYPGQQQNFHSVREMF
:.: .. .:::::..: ::.:: . . :: :::.: .:::::
CCDS10 PPAPQPQPTPQPGAAAAQAASWYLNHSG-DLNHLPGHTFAA-------QQQTFPNVREMF
410 420 430 440 450
520 530 540 550
pF1KB9 ESQRIGLNNSP-----VNGNSSCQMAFPSSQSLYRTSGAFVYDCSKF
.:.:.:..:: :.::.:::. . :. ::: .. . :::.:.
CCDS10 NSHRLGIENSTLGESQVSGNASCQLPYRSTPPLYRHAAPYSYDCTKY
460 470 480 490 500
>>CCDS13192.1 FOXS1 gene_id:2307|Hs108|chr20 (330 aa)
initn: 658 init1: 571 opt: 655 Z-score: 311.7 bits: 66.7 E(32554): 4.8e-11
Smith-Waterman score: 684; 44.6% identity (62.2% similar) in 278 aa overlap (65-301:8-282)
40 50 60 70 80 90
pF1KB9 GGYTAMPAPMSVYSHPAHAEQYPGGMARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNA
:: .: .: .::::::::::.::::..
CCDS13 MQQQPLPGPGAPTTEP---TKPPYSYIALIAMAIQSS
10 20 30
100 110 120 130 140 150
pF1KB9 PDKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTL
: .. ::.:::..:: :: ::: :. :::::::::::::::::::::::.::::::::::
CCDS13 PGQRATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTL
40 50 60 70 80 90
160 170 180 190 200
pF1KB9 DPDSYNMFENGSFLRRRRRFKKKDAV-------KDKEEKDRLHLKEPPPP----GRQ---
::: ..:::.:::::::::: .. .. : .. : ..: : :::
CCDS13 DPDCHDMFEHGSFLRRRRRFTRQTGAEGTRGPAKARRGPLRATSQDPGVPNATTGRQCSF
100 110 120 130 140 150
210 220 230 240
pF1KB9 PP--PAPPEQADGNAPGPQP-------------PPVRIQDIKTENGTCPSP-PQPLSPAA
:: : : . :. : .: ::.. ..:.: . .::. : : ..
CCDS13 PPELPDPKGLSFGGLVGAMPASMCPATTDGRPRPPMEPKEISTPKPACPGELPVATSSSS
160 170 180 190 200 210
250 260 270 280 290
pF1KB9 ALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLD---GAD--------SAPP
. : :. . :: ... . . : : :: . : .:. ::: :: :
CCDS13 CPAFGFPAGFSEAESFNKAPTPVLSPESGIGSSYQCRLQALNFCMGADPGLEHLLASAAP
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB9 PPAPSAPPPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAY
::: .::
CCDS13 SPAPPTPPGSLRAPLPLPTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPGMFFFE
280 290 300 310 320 330
>>CCDS75259.1 FOXD1 gene_id:2297|Hs108|chr5 (465 aa)
initn: 590 init1: 514 opt: 649 Z-score: 307.2 bits: 66.4 E(32554): 8.6e-11
Smith-Waterman score: 655; 37.7% identity (58.4% similar) in 361 aa overlap (31-387:80-419)
10 20 30 40 50 60
pF1KB9 MQARYSVSSPNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGM
: .:: : :.: . . : : ::
CCDS75 AQRRRRRRSYAGEDELEDLEEEEDDDDILLAPPAGGSPAPPGPAPAAG--AGAGGGGGGG
50 60 70 80 90 100
70 80 90 100 110 120
pF1KB9 ARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQ
. . : . . . .::::::::::::::: ..: :..::. : .:: :::.::..
CCDS75 GAGGGGSAGSGAKNPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFP
110 120 130 140 150 160
130 140 150 160 170 180
pF1KB9 GWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAV
.::::::::::::.::::.::. .::::.::::::.: .::.::::::::.:::.. .
CCDS75 AWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLL
170 180 190 200 210 220
190 200 210 220 230
pF1KB9 K-DKEEKDRLHLKEPPPPGRQPPPAPPEQADGNAPGPQPPPVRIQDIKTENGTCPSPPQP
. . : :. : :: : :.: ::: : . : :
CCDS75 PPNAAAAESLLLRGAGAAGGAGDPAAA--AALFPPAPPPPPHAYGYGPYGCGYGLQLP-P
230 240 250 260 270 280
240 250 260 270 280 290
pF1KB9 LSPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLP--SARPLSLDGADSAPPPPAP
.: .:: ...::: ...... : :: : .: :. . : : .
CCDS75 YAPPSALFAAAAAA--------AAAAAFHPHSPPPPPPPHGAAAELARTAFGYRPHPLGA
290 300 310 320 330
300 310 320 330 340 350
pF1KB9 SAPPPHHSQGFSVDNIMTS-LRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPG
. : : ... .. . .: : :: : . . .: :. :::.. :. : : .. ::
CCDS75 ALPGPLPASAAKAGGPGASALARSPFSIES-IIGGSLGPAAAAAAAAQAAAAAQASPSP-
340 350 360 370 380 390
360 370 380 390 400 410
pF1KB9 QSSLYSSPCSQTSSAGSSGGGGGGAGAAGGAGGAGTYHCNLQAMSLYAAGERGGHLQGAP
:: . . :::::: .. .:.: :
CCDS75 ------SPVAAPPAPGSSGGGCAAQAAVGPAAALTRSLVAAAAAAASSVSSSAALGTLHQ
400 410 420 430 440
420 430 440 450 460 470
pF1KB9 GGAGGSAVDDPLPDYSLPPVTSSSSSSLSHGGGGGGGGGGQEAGHHPAAHQGRLTSWYLN
CCDS75 GTALSSVENFTARISNC
450 460
553 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 03:43:51 2016 done: Tue Nov 8 03:43:51 2016
Total Scan time: 4.620 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]