Result of FASTA (omim) for
pFN21AE6540
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6540, 85 aa
1>>>pF1KE6540 85 - 85 aa - 85 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6080+/-0.000258; mu= 12.3221+/- 0.016
mean_var=66.7394+/-13.497, 0's: 0 Z-trim(120.1): 53 B-trim: 0 in 0/54
Lambda= 0.156994
statistics sampled from 34916 (34983) to 34916 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.795), E-opt: 0.2 (0.41), width: 16
Scan time: 2.690
The best scores are: opt bits E(85289)
NP_001035523 (OMIM: 613511) serine protease inhibi ( 86) 208 54.6 2.2e-08
XP_016865198 (OMIM: 613511) PREDICTED: serine prot ( 107) 190 50.6 4.4e-07
NP_995313 (OMIM: 615868) serine protease inhibitor ( 80) 180 48.3 1.7e-06
NP_001182219 (OMIM: 615868) serine protease inhibi ( 80) 180 48.3 1.7e-06
XP_011532707 (OMIM: 605753) PREDICTED: serine prot ( 186) 155 42.9 0.00016
NP_066937 (OMIM: 605753) serine protease inhibitor ( 84) 149 41.3 0.00023
NP_001258649 (OMIM: 605753) serine protease inhibi ( 119) 146 40.7 0.00048
NP_003113 (OMIM: 167790,167800,608189) serine prot ( 79) 144 40.1 0.00049
NP_001258647 (OMIM: 605753) serine protease inhibi ( 134) 146 40.8 0.00052
NP_055286 (OMIM: 613929) serine protease inhibitor ( 86) 137 38.5 0.0016
NP_001121171 (OMIM: 147050,256500,605010) serine p ( 916) 145 41.3 0.0025
NP_001035218 (OMIM: 615205) serine protease inhibi ( 94) 134 37.9 0.0027
XP_011539731 (OMIM: 103320,615120) PREDICTED: agri (2004) 148 42.3 0.0027
NP_006837 (OMIM: 147050,256500,605010) serine prot (1064) 145 41.4 0.0027
XP_011535853 (OMIM: 147050,256500,605010) PREDICTE (1066) 145 41.4 0.0027
NP_940978 (OMIM: 103320,615120) agrin isoform 2 pr (2045) 148 42.3 0.0027
XP_005244806 (OMIM: 103320,615120) PREDICTED: agri (2049) 148 42.3 0.0027
NP_001292204 (OMIM: 103320,615120) agrin isoform 1 (2068) 148 42.3 0.0028
NP_001121170 (OMIM: 147050,256500,605010) serine p (1094) 145 41.4 0.0028
>>NP_001035523 (OMIM: 613511) serine protease inhibitor (86 aa)
initn: 144 init1: 77 opt: 208 Z-score: 271.3 bits: 54.6 E(85289): 2.2e-08
Smith-Waterman score: 208; 39.5% identity (61.6% similar) in 86 aa overlap (1-85:1-86)
10 20 30 40 50
pF1KE6 MKITGGLLLLCTVVYFCSSSEAASLSPKKVDCSIYKKYPVVAIP-CPITYLPVCGSDYIT
:. :. .::: .. : : :. . . :::: ::: : : : :.:::: :
NP_001 MRATAIVLLLALTLATMFSIECAKQTKQMVDCSHYKKLPPGQQRFCHHMYDPICGSDGKT
10 20 30 40 50 60
60 70 80
pF1KE6 YGNECHLCTESLKSNGRVQFLHDGSC
: :.: .:.. :..: ..:.: :.:
NP_001 YKNDCFFCSKVKKTDGTLKFVHFGKC
70 80
>>XP_016865198 (OMIM: 613511) PREDICTED: serine protease (107 aa)
initn: 128 init1: 77 opt: 190 Z-score: 248.1 bits: 50.6 E(85289): 4.4e-07
Smith-Waterman score: 190; 42.4% identity (63.6% similar) in 66 aa overlap (21-85:42-107)
10 20 30 40
pF1KE6 MKITGGLLLLCTVVYFCSSSEAASLSPKKVDCSIYKKYPVVAIP-CPITY
: :. . . :::: ::: : : :
XP_016 HYKTPPSSSGEHNEPRRLMGLTQPEHLQGIECAKQTKQMVDCSHYKKLPPGQQRFCHHMY
20 30 40 50 60 70
50 60 70 80
pF1KE6 LPVCGSDYITYGNECHLCTESLKSNGRVQFLHDGSC
:.:::: :: :.: .:.. :..: ..:.: :.:
XP_016 DPICGSDGKTYKNDCFFCSKVKKTDGTLKFVHFGKC
80 90 100
>>NP_995313 (OMIM: 615868) serine protease inhibitor Kaz (80 aa)
initn: 175 init1: 132 opt: 180 Z-score: 237.5 bits: 48.3 E(85289): 1.7e-06
Smith-Waterman score: 180; 37.6% identity (63.5% similar) in 85 aa overlap (1-85:1-80)
10 20 30 40 50 60
pF1KE6 MKITGGLLLLCTVVYFCSSSEAASLSPKKVDCSIYKKYPVVAIPCPITYLPVCGSDYITY
::..: .::: ... :: . . : . . :::. .. : : : : :::: ::
NP_995 MKLSGMFLLL-SLALFCFLTGVFSQGGQ-VDCGEFQD-PKVY--CTRESNPHCGSDGQTY
10 20 30 40 50
70 80
pF1KE6 GNECHLCTESLKSNGRVQFLHDGSC
::.: .: .::.:.... : :.:
NP_995 GNKCAFCKAIVKSGGKISLKHPGKC
60 70 80
>>NP_001182219 (OMIM: 615868) serine protease inhibitor (80 aa)
initn: 175 init1: 132 opt: 180 Z-score: 237.5 bits: 48.3 E(85289): 1.7e-06
Smith-Waterman score: 180; 37.6% identity (63.5% similar) in 85 aa overlap (1-85:1-80)
10 20 30 40 50 60
pF1KE6 MKITGGLLLLCTVVYFCSSSEAASLSPKKVDCSIYKKYPVVAIPCPITYLPVCGSDYITY
::..: .::: ... :: . . : . . :::. .. : : : : :::: ::
NP_001 MKLSGMFLLL-SLALFCFLTGVFSQGGQ-VDCGEFQD-PKVY--CTRESNPHCGSDGQTY
10 20 30 40 50
70 80
pF1KE6 GNECHLCTESLKSNGRVQFLHDGSC
::.: .: .::.:.... : :.:
NP_001 GNKCAFCKAIVKSGGKISLKHPGKC
60 70 80
>>XP_011532707 (OMIM: 605753) PREDICTED: serine protease (186 aa)
initn: 146 init1: 118 opt: 155 Z-score: 202.1 bits: 42.9 E(85289): 0.00016
Smith-Waterman score: 158; 32.9% identity (57.3% similar) in 82 aa overlap (5-85:116-186)
10 20 30
pF1KE6 MKITGGLLLLCTVVYFCSSSEAASLSPKKVDCSI
:: : . :: . :.. .::
XP_011 FPRPPRAPSHERSLRVAQVTDRRGKTAGAGGGWRCRCCAWRCCSWQL-----PSQPNCSQ
90 100 110 120 130 140
40 50 60 70 80
pF1KE6 YKKYPVVAIP-CPITYLPVCGSDYITYGNECHLCTESLKSNGRVQFLHDGSC
:. .: :: . ::::::. ::.::: :: . ... ......: :
XP_011 YR------LPGCPRHFNPVCGSDMSTYANECTLCMKIREGGHNIKIIRNGPC
150 160 170 180
>>NP_066937 (OMIM: 605753) serine protease inhibitor Kaz (84 aa)
initn: 162 init1: 118 opt: 149 Z-score: 199.3 bits: 41.3 E(85289): 0.00023
Smith-Waterman score: 149; 36.5% identity (61.2% similar) in 85 aa overlap (7-85:8-84)
10 20 30 40 50
pF1KE6 MKITGGLLLLCTVVYFCSSSEAASLSPKKVDCSIYKKY--PVVA---IP-CPITYLPVC
: :: .: : :::: :. ....:: : . .: :: . :::
NP_066 MALSVLRLALLLLAVTF-----AASLIPQ---FGLFSKYRTPNCSQYRLPGCPRHFNPVC
10 20 30 40 50
60 70 80
pF1KE6 GSDYITYGNECHLCTESLKSNGRVQFLHDGSC
:::. ::.::: :: . ... ......: :
NP_066 GSDMSTYANECTLCMKIREGGHNIKIIRNGPC
60 70 80
>>NP_001258649 (OMIM: 605753) serine protease inhibitor (119 aa)
initn: 127 init1: 118 opt: 146 Z-score: 193.6 bits: 40.7 E(85289): 0.00048
Smith-Waterman score: 146; 37.5% identity (66.1% similar) in 56 aa overlap (31-85:70-119)
10 20 30 40 50
pF1KE6 MKITGGLLLLCTVVYFCSSSEAASLSPKKVDCSIYKKYPVVAIP-CPITYLPVCGSDYIT
.:: :. .: :: . ::::::. :
NP_001 TGGGPCPAPGGLGDASLIPQFGLFSKYRTPNCSQYR------LPGCPRHFNPVCGSDMST
40 50 60 70 80 90
60 70 80
pF1KE6 YGNECHLCTESLKSNGRVQFLHDGSC
:.::: :: . ... ......: :
NP_001 YANECTLCMKIREGGHNIKIIRNGPC
100 110
>>NP_003113 (OMIM: 167790,167800,608189) serine protease (79 aa)
initn: 151 init1: 115 opt: 144 Z-score: 193.5 bits: 40.1 E(85289): 0.00049
Smith-Waterman score: 144; 32.9% identity (56.5% similar) in 85 aa overlap (1-85:1-79)
10 20 30 40 50 60
pF1KE6 MKITGGLLLLCTVVYFCSSSEAASLSPKKVDCSIYKKYPVVAIPCPITYLPVCGSDYITY
::.:: .:: .. :.. .:. ... : :.. : : ::::.: ::
NP_003 MKVTGIFLLSALALLSLSGNTGADSLGREAKC--YNELN----GCTKIYDPVCGTDGNTY
10 20 30 40 50
70 80
pF1KE6 GNECHLCTESLKSNGRVQFLHDGSC
::: :: :. : . . . ..: :
NP_003 PNECVLCFENRKRQTSILIQKSGPC
60 70
>>NP_001258647 (OMIM: 605753) serine protease inhibitor (134 aa)
initn: 127 init1: 118 opt: 146 Z-score: 193.0 bits: 40.8 E(85289): 0.00052
Smith-Waterman score: 146; 37.5% identity (66.1% similar) in 56 aa overlap (31-85:85-134)
10 20 30 40 50
pF1KE6 MKITGGLLLLCTVVYFCSSSEAASLSPKKVDCSIYKKYPVVAIP-CPITYLPVCGSDYIT
.:: :. .: :: . ::::::. :
NP_001 TRAPVTGGSPEDLPASLIPQFGLFSKYRTPNCSQYR------LPGCPRHFNPVCGSDMST
60 70 80 90 100
60 70 80
pF1KE6 YGNECHLCTESLKSNGRVQFLHDGSC
:.::: :: . ... ......: :
NP_001 YANECTLCMKIREGGHNIKIIRNGPC
110 120 130
>>NP_055286 (OMIM: 613929) serine protease inhibitor Kaz (86 aa)
initn: 143 init1: 137 opt: 137 Z-score: 184.4 bits: 38.5 E(85289): 0.0016
Smith-Waterman score: 137; 47.1% identity (79.4% similar) in 34 aa overlap (52-85:53-86)
30 40 50 60 70 80
pF1KE6 AASLSPKKVDCSIYKKYPVVAIPCPITYLPVCGSDYITYGNECHLCTESLKSNGRVQFLH
:::.: .:: :::.:: .:.. .:...
NP_055 PVAAGKLPFSRMPICEHMVESPTCSQMSNLVCGTDGLTYTNECQLCLARIKTKQDIQIMK
30 40 50 60 70 80
pF1KE6 DGSC
::.:
NP_055 DGKC
85 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 14:14:24 2016 done: Tue Nov 8 14:14:24 2016
Total Scan time: 2.690 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]