Result of FASTA (ccds) for
pFN21AE3056
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3056, 212 aa
1>>>pF1KE3056 212 - 212 aa - 212 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0245+/-0.000758; mu= 14.4669+/- 0.046
mean_var=58.8943+/-11.855, 0's: 0 Z-trim(107.7): 29 B-trim: 0 in 0/49
Lambda= 0.167124
statistics sampled from 9693 (9720) to 9693 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.703), E-opt: 0.2 (0.299), width: 16
Scan time: 2.090
The best scores are: opt bits E(32554)
CCDS4197.1 NME5 gene_id:8382|Hs108|chr5 ( 212) 1433 353.6 5.4e-98
CCDS44274.1 NME7 gene_id:29922|Hs108|chr1 ( 340) 397 103.9 1.3e-22
CCDS1277.1 NME7 gene_id:29922|Hs108|chr1 ( 376) 397 103.9 1.4e-22
CCDS77734.1 NME6 gene_id:10201|Hs108|chr3 ( 186) 353 93.1 1.2e-19
CCDS2763.1 NME6 gene_id:10201|Hs108|chr3 ( 194) 353 93.1 1.2e-19
CCDS5452.1 NME8 gene_id:51314|Hs108|chr7 ( 588) 304 81.6 1.1e-15
CCDS82767.1 NME6 gene_id:10201|Hs108|chr3 ( 141) 287 77.2 5.8e-15
CCDS3099.1 NME9 gene_id:347736|Hs108|chr3 ( 263) 287 77.3 9.7e-15
CCDS11580.1 NME2 gene_id:4831|Hs108|chr17 ( 152) 247 67.5 4.9e-12
CCDS32682.1 NME2 gene_id:654364|Hs108|chr17 ( 267) 247 67.7 7.9e-12
>>CCDS4197.1 NME5 gene_id:8382|Hs108|chr5 (212 aa)
initn: 1433 init1: 1433 opt: 1433 Z-score: 1872.8 bits: 353.6 E(32554): 5.4e-98
Smith-Waterman score: 1433; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212)
10 20 30 40 50 60
pF1KE3 MEISMPPPQIYVEKTLAIIKPDIVDKEEEIQDIILRSGFTIVQRRKLRLSPEQCSNFYVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 MEISMPPPQIYVEKTLAIIKPDIVDKEEEIQDIILRSGFTIVQRRKLRLSPEQCSNFYVE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KYGKMFFPNLTAYMSSGPLVAMILARHKAISYWLELLGPNNSLVAKETHPDSLRAIYGTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 KYGKMFFPNLTAYMSSGPLVAMILARHKAISYWLELLGPNNSLVAKETHPDSLRAIYGTD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DLRNALHGSNDFAAAEREIRFMFPEVIVEPIPIGQAAKDYLNLHIMPTLLEGLTELCKQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS41 DLRNALHGSNDFAAAEREIRFMFPEVIVEPIPIGQAAKDYLNLHIMPTLLEGLTELCKQK
130 140 150 160 170 180
190 200 210
pF1KE3 PADPLIWLADWLLKNNPNKPKLCHHPIVEEPY
::::::::::::::::::::::::::::::::
CCDS41 PADPLIWLADWLLKNNPNKPKLCHHPIVEEPY
190 200 210
>>CCDS44274.1 NME7 gene_id:29922|Hs108|chr1 (340 aa)
initn: 418 init1: 397 opt: 397 Z-score: 519.7 bits: 103.9 E(32554): 1.3e-22
Smith-Waterman score: 397; 44.7% identity (75.0% similar) in 132 aa overlap (13-144:56-187)
10 20 30 40
pF1KE3 MEISMPPPQIYVEKTLAIIKPDIVDKEEEIQDIILRSGFTIV
:::::.:::: ..: :: .:: ..::::.
CCDS44 IGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLALIKPDAISKAGEIIEIINKAGFTIT
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE3 QRRKLRLSPEQCSNFYVEKYGKMFFPNLTAYMSSGPLVAMILARHKAISYWLELLGPNNS
. . . :: .. .:.:.. .. :: .: ....::..:: . : :: : .:::: ::
CCDS44 KLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTGPIIAMEILRDDAICEWKRLLGPANS
90 100 110 120 130 140
110 120 130 140 150 160
pF1KE3 LVAKETHPDSLRAIYGTDDLRNALHGSNDFAAAEREIRFMFPEVIVEPIPIGQAAKDYLN
::. .:.::..::: .::: :: ..::.: ::....::
CCDS44 GVARTDASESIRALFGTDGIRNAAHGPDSFASAAREMELFFPSSGGCGPANTAKFTNCTC
150 160 170 180 190 200
170 180 190 200 210
pF1KE3 LHIMPTLLEGLTELCKQKPADPLIWLADWLLKNNPNKPKLCHHPIVEEPY
CCDS44 CIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTE
210 220 230 240 250 260
>>CCDS1277.1 NME7 gene_id:29922|Hs108|chr1 (376 aa)
initn: 418 init1: 397 opt: 397 Z-score: 519.1 bits: 103.9 E(32554): 1.4e-22
Smith-Waterman score: 397; 44.7% identity (75.0% similar) in 132 aa overlap (13-144:92-223)
10 20 30 40
pF1KE3 MEISMPPPQIYVEKTLAIIKPDIVDKEEEIQDIILRSGFTIV
:::::.:::: ..: :: .:: ..::::.
CCDS12 IGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLALIKPDAISKAGEIIEIINKAGFTIT
70 80 90 100 110 120
50 60 70 80 90 100
pF1KE3 QRRKLRLSPEQCSNFYVEKYGKMFFPNLTAYMSSGPLVAMILARHKAISYWLELLGPNNS
. . . :: .. .:.:.. .. :: .: ....::..:: . : :: : .:::: ::
CCDS12 KLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTGPIIAMEILRDDAICEWKRLLGPANS
130 140 150 160 170 180
110 120 130 140 150 160
pF1KE3 LVAKETHPDSLRAIYGTDDLRNALHGSNDFAAAEREIRFMFPEVIVEPIPIGQAAKDYLN
::. .:.::..::: .::: :: ..::.: ::....::
CCDS12 GVARTDASESIRALFGTDGIRNAAHGPDSFASAAREMELFFPSSGGCGPANTAKFTNCTC
190 200 210 220 230 240
170 180 190 200 210
pF1KE3 LHIMPTLLEGLTELCKQKPADPLIWLADWLLKNNPNKPKLCHHPIVEEPY
CCDS12 CIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTE
250 260 270 280 290 300
>>CCDS77734.1 NME6 gene_id:10201|Hs108|chr3 (186 aa)
initn: 347 init1: 311 opt: 353 Z-score: 466.3 bits: 93.1 E(32554): 1.2e-19
Smith-Waterman score: 353; 41.1% identity (69.5% similar) in 141 aa overlap (8-145:8-147)
10 20 30 40 50
pF1KE3 MEISMPPPQIYVEKTLAIIKPDIVDKE---EEIQDIILRSGFTIVQRRKLRLSPEQCSNF
:: .. :::.:::: : . : ... :: . : ::. :.: :.:. :
CCDS77 MASILRSPQA-LQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWRKEDCQRF
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 YVEKYGKMFFPNLTAYMSSGPLVAMILARHKAISYWLELLGPNNSLVAKETHPDSLRAIY
: :. :..:. :. .:.:::. :.:::.. ::. : :.::. . :... :::.:. .
CCDS77 YREHEGRFFYQRLVEFMASGPIRAYILAHKDAIQLWRTLMGPTRVFRARHVAPDSIRGSF
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 GTDDLRNALHGSNDFAAAEREIRFMFPEVIVEPIPIGQAAKDYLNLHIMPTLLEGLTELC
: : ::. :::.. ..: ::: .::.
CCDS77 GLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVCYSPEGGVHYVAG
120 130 140 150 160 170
>>CCDS2763.1 NME6 gene_id:10201|Hs108|chr3 (194 aa)
initn: 347 init1: 311 opt: 353 Z-score: 466.1 bits: 93.1 E(32554): 1.2e-19
Smith-Waterman score: 353; 41.1% identity (69.5% similar) in 141 aa overlap (8-145:16-155)
10 20 30 40
pF1KE3 MEISMPPPQIYVEKTLAIIKPDIVDKE---EEIQDIILRSGFTIVQRRKLRL
:: .. :::.:::: : . : ... :: . : ::. :.:
CCDS27 MTQNLGSEMASILRSPQA-LQLTLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLW
10 20 30 40 50
50 60 70 80 90 100
pF1KE3 SPEQCSNFYVEKYGKMFFPNLTAYMSSGPLVAMILARHKAISYWLELLGPNNSLVAKETH
:.:. :: :. :..:. :. .:.:::. :.:::.. ::. : :.::. . :...
CCDS27 RKEDCQRFYREHEGRFFYQRLVEFMASGPIRAYILAHKDAIQLWRTLMGPTRVFRARHVA
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE3 PDSLRAIYGTDDLRNALHGSNDFAAAEREIRFMFPEVIVEPIPIGQAAKDYLNLHIMPTL
:::.:. .: : ::. :::.. ..: ::: .::.
CCDS27 PDSIRGSFGLTDTRNTTHGSDSVVSASREIAAFFPDFSEQRWYEEEEPQLRCGPVCYSPE
120 130 140 150 160 170
170 180 190 200 210
pF1KE3 LEGLTELCKQKPADPLIWLADWLLKNNPNKPKLCHHPIVEEPY
CCDS27 GGVHYVAGTGGLGPA
180 190
>>CCDS5452.1 NME8 gene_id:51314|Hs108|chr7 (588 aa)
initn: 528 init1: 251 opt: 304 Z-score: 395.0 bits: 81.6 E(32554): 1.1e-15
Smith-Waterman score: 304; 35.0% identity (70.1% similar) in 137 aa overlap (12-145:450-586)
10 20 30 40
pF1KE3 MEISMPPPQIYVEKTLAIIKPDIV-DKEEEIQDIILRSGFT
...::..::: . ...:.: :. ..::
CCDS54 QFAMDSLPVNQLYGSDSLETAEREIQHFFPLQSTLGLIKPHATSEQREQILKIVKEAGFD
420 430 440 450 460 470
50 60 70 80 90 100
pF1KE3 IVQRRKLRLSPEQCSNFYVEKYGKMFFPNLTAYMSSGPLVAMILARHKAISYWLELLGPN
..: .:. :.::: ..: . :: :. .: ..: :: ..:::.. .:.. : .:.::.
CCDS54 LTQVKKMFLTPEQIEKIYPKVTGKDFYKDLLEMLSVGPSMVMILTKWNAVAEWRRLMGPT
480 490 500 510 520 530
110 120 130 140 150
pF1KE3 NSLVAKETHPDSLRAIYGTDDLRNALHGSNDFAAAEREIRFMF--PEVIVEPIPIGQAAK
. :: :::.:: .: . :.: .::... :.. . .: ::
CCDS54 DPEEAKLLSPDSIRAQFGISKLKNIVHGASNAYEAKEVVNRLFEDPEEN
540 550 560 570 580
160 170 180 190 200 210
pF1KE3 DYLNLHIMPTLLEGLTELCKQKPADPLIWLADWLLKNNPNKPKLCHHPIVEEPY
>--
initn: 366 init1: 176 opt: 282 Z-score: 366.3 bits: 76.3 E(32554): 4.4e-14
Smith-Waterman score: 282; 35.6% identity (69.6% similar) in 135 aa overlap (12-144:315-449)
10 20 30 40
pF1KE3 MEISMPPPQIYVEKTLAIIKPDIV-DKEEEIQDIILRSGFT
.:::::...:.. ...... :: :
CCDS54 QLCDIEEDAANVAKFMDAFFPDFKKMKSMKLEKTLALLRPNLFHERKDDVLRIIKDEDFK
290 300 310 320 330 340
50 60 70 80 90 100
pF1KE3 IVQRRKLRLSPEQCSNFYVEKYGKMFFPNLTAYMSSGPLVAMILARHKAISYWLELLGPN
:...:.. :: .. . . : .. .: .: :.::: .:..: : ....:: .::::
CCDS54 ILEQRQVVLSEKEAQALCKEYENEDYFNKLIENMTSGPSLALVLLRDNGLQYWKQLLGPR
350 360 370 380 390 400
110 120 130 140 150
pF1KE3 NSLVAKETHPDSLRAIYGTDDLR-NALHGSNDFAAAEREIRFMFPEVIVEPIPIGQAAKD
. : : :.:: : .. :.: : :.::... .:::::. .::
CCDS54 TVEEAIEYFPESLCAQFAMDSLPVNQLYGSDSLETAEREIQHFFPLQSTLGLIKPHATSE
410 420 430 440 450 460
160 170 180 190 200 210
pF1KE3 YLNLHIMPTLLEGLTELCKQKPADPLIWLADWLLKNNPNKPKLCHHPIVEEPY
CCDS54 QREQILKIVKEAGFDLTQVKKMFLTPEQIEKIYPKVTGKDFYKDLLEMLSVGPSMVMILT
470 480 490 500 510 520
>>CCDS82767.1 NME6 gene_id:10201|Hs108|chr3 (141 aa)
initn: 263 init1: 263 opt: 287 Z-score: 382.2 bits: 77.2 E(32554): 5.8e-15
Smith-Waterman score: 287; 41.6% identity (72.3% similar) in 101 aa overlap (45-145:2-102)
20 30 40 50 60 70
pF1KE3 TLAIIKPDIVDKEEEIQDIILRSGFTIVQRRKLRLSPEQCSNFYVEKYGKMFFPNLTAYM
:.: :.:. :: :. :..:. :. .:
CCDS82 MRELLWRKEDCQRFYREHEGRFFYQRLVEFM
10 20 30
80 90 100 110 120 130
pF1KE3 SSGPLVAMILARHKAISYWLELLGPNNSLVAKETHPDSLRAIYGTDDLRNALHGSNDFAA
.:::. :.:::.. ::. : :.::. . :... :::.:. .: : ::. :::.. ..
CCDS82 ASGPIRAYILAHKDAIQLWRTLMGPTRVFRARHVAPDSIRGSFGLTDTRNTTHGSDSVVS
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 AEREIRFMFPEVIVEPIPIGQAAKDYLNLHIMPTLLEGLTELCKQKPADPLIWLADWLLK
: ::: .::.
CCDS82 ASREIAAFFPDFSEQRWYEEEEPQLRCGPVCYSPEGGVHYVAGTGGLGPA
100 110 120 130 140
>>CCDS3099.1 NME9 gene_id:347736|Hs108|chr3 (263 aa)
initn: 286 init1: 168 opt: 287 Z-score: 378.1 bits: 77.3 E(32554): 9.7e-15
Smith-Waterman score: 287; 39.0% identity (63.2% similar) in 136 aa overlap (15-144:100-235)
10 20 30 40
pF1KE3 MEISMPPPQIYVEKTLAIIKPDIV--DKEEEIQDIILRSGFTIV
:::::::: : : .:: : ..:: :.
CCDS30 DEALSDEDECVSHGKNNGEDEDMVSSERTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEIL
70 80 90 100 110 120
50 60 70 80 90
pF1KE3 QRRKLRLSPEQCSNFYVEKYGKMFFPNLTAYMSSGPLVAMILARHKA----ISYWLELLG
.. .. . :: .: :. : .:. .: ::: .::.: .. .. : ..:
CCDS30 TNEERTMTEAEVRLFYQHKAGEEAFEKLVHHMCSGPSHLLILTRTEGFEDVVTTWRTVMG
130 140 150 160 170 180
100 110 120 130 140 150
pF1KE3 PNNSLVAKETHPDSLRAIYGTDDLRNALHGSNDFAAAEREIRFMFPEVIVEPIPIGQAAK
: . ::.. .:.:::: :::. ::.::: : :.::. ..::
CCDS30 PRDPNVARREQPESLRAQYGTEMPFNAVHGSRDREDADRELALLFPSLKFSDKDTEAPQG
190 200 210 220 230 240
160 170 180 190 200 210
pF1KE3 DYLNLHIMPTLLEGLTELCKQKPADPLIWLADWLLKNNPNKPKLCHHPIVEEPY
CCDS30 ESSTQPRLKITDLD
250 260
>>CCDS11580.1 NME2 gene_id:4831|Hs108|chr17 (152 aa)
initn: 212 init1: 136 opt: 247 Z-score: 329.5 bits: 67.5 E(32554): 4.9e-12
Smith-Waterman score: 247; 33.8% identity (64.1% similar) in 142 aa overlap (12-149:4-141)
10 20 30 40 50
pF1KE3 MEISMPPPQIYVEKTLAIIKPDIVDKEEEIQDIILR---SGFTIVQRRKLRLSPEQCSNF
.:.:. :::: :.. . .:: : .:: .: . :: : :. ..
CCDS11 MANLERTFIAIKPDGVQRGL-VGEIIKRFEQKGFRLVAMKFLRASEEHLKQH
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 YVEKYGKMFFPNLTAYMSSGPLVAMILARHKAISYWLELLGPNNSLVAKETHPDSLRAIY
:.. . :::.:. ::.:::.:::. .... .:: .: ...: ..:. .
CCDS11 YIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETNP---ADSKPGTIRGDF
60 70 80 90 100
120 130 140 150 160 170
pF1KE3 GTDDLRNALHGSNDFAAAEREIRFMF-PEVIVEPIPIGQAAKDYLNLHIMPTLLEGLTEL
. :: .:::.. .::.:: . : :: .:.
CCDS11 CIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDWVYE
110 120 130 140 150
180 190 200 210
pF1KE3 CKQKPADPLIWLADWLLKNNPNKPKLCHHPIVEEPY
>>CCDS32682.1 NME2 gene_id:654364|Hs108|chr17 (267 aa)
initn: 231 init1: 136 opt: 247 Z-score: 325.8 bits: 67.7 E(32554): 7.9e-12
Smith-Waterman score: 247; 33.8% identity (64.1% similar) in 142 aa overlap (12-149:119-256)
10 20 30
pF1KE3 MEISMPPPQIYVEKTLAIIKPDIVDKEEEIQDIILR---SG
.:.:. :::: :.. . .:: : .:
CCDS32 VMLGETNPADSKPGTIRGDFCIQVGRTMANLERTFIAIKPDGVQRGL-VGEIIKRFEQKG
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE3 FTIVQRRKLRLSPEQCSNFYVEKYGKMFFPNLTAYMSSGPLVAMILARHKAISYWLELLG
: .: . :: : :. .. :.. . :::.:. ::.:::.:::. .... .::
CCDS32 FRLVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLG
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE3 PNNSLVAKETHPDSLRAIYGTDDLRNALHGSNDFAAAEREIRFMF-PEVIVEPIPIGQAA
.: ...: ..:. . . :: .:::.. .::.:: . : :: .:.
CCDS32 ETNP---ADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDW
210 220 230 240 250 260
160 170 180 190 200 210
pF1KE3 KDYLNLHIMPTLLEGLTELCKQKPADPLIWLADWLLKNNPNKPKLCHHPIVEEPY
CCDS32 VYE
212 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:07:16 2016 done: Sun Nov 6 17:07:16 2016
Total Scan time: 2.090 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]