Result of FASTA (omim) for
pFN21AE9546
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9546, 522 aa
1>>>pF1KE9546 522 - 522 aa - 522 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2655+/-0.000471; mu= 19.0288+/- 0.029
mean_var=107.5365+/-27.051, 0's: 0 Z-trim(110.2): 655 B-trim: 976 in 1/49
Lambda= 0.123679
statistics sampled from 17691 (18483) to 17691 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.556), E-opt: 0.2 (0.217), width: 16
Scan time: 8.740
The best scores are: opt bits E(85289)
NP_004876 (OMIM: 607449) neuropeptide FF receptor ( 522) 3526 641.0 2.6e-183
NP_001138228 (OMIM: 607449) neuropeptide FF recept ( 423) 2817 514.4 2.7e-145
NP_444264 (OMIM: 607449) neuropeptide FF receptor ( 420) 2804 512.0 1.4e-144
XP_011529856 (OMIM: 607449) PREDICTED: neuropeptid ( 304) 1995 367.5 3.1e-101
NP_071429 (OMIM: 607448) neuropeptide FF receptor ( 430) 1381 258.1 3.8e-68
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 649 127.5 7.8e-29
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 591 117.1 9.5e-26
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384) 591 117.1 9.5e-26
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 591 117.1 9.5e-26
NP_057624 (OMIM: 605569) probable G-protein couple ( 423) 545 109.0 3e-23
NP_005963 (OMIM: 601790) neuropeptide Y receptor t ( 375) 539 107.8 5.8e-23
XP_011538239 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 539 107.8 5.8e-23
XP_016871875 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 539 107.8 5.8e-23
XP_016871876 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 539 107.8 5.8e-23
NP_001265723 (OMIM: 601790) neuropeptide Y recepto ( 375) 539 107.8 5.8e-23
XP_011538238 (OMIM: 601790) PREDICTED: neuropeptid ( 375) 539 107.8 5.8e-23
NP_001517 (OMIM: 602393) orexin receptor type 2 [H ( 444) 530 106.3 2e-22
XP_016866287 (OMIM: 602393) PREDICTED: orexin rece ( 461) 530 106.3 2e-22
XP_016856596 (OMIM: 602392) PREDICTED: orexin rece ( 389) 490 99.1 2.5e-20
NP_001516 (OMIM: 602392) orexin receptor type 1 [H ( 425) 490 99.1 2.7e-20
XP_016856595 (OMIM: 602392) PREDICTED: orexin rece ( 425) 490 99.1 2.7e-20
XP_016856594 (OMIM: 602392) PREDICTED: orexin rece ( 425) 490 99.1 2.7e-20
NP_001718 (OMIM: 300107) bombesin receptor subtype ( 399) 486 98.4 4.2e-20
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390) 479 97.1 9.9e-20
NP_000721 (OMIM: 118444) cholecystokinin receptor ( 428) 445 91.1 7.1e-18
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381) 434 89.1 2.6e-17
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 434 89.1 2.6e-17
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 434 89.1 2.6e-17
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384) 433 88.9 2.9e-17
NP_115940 (OMIM: 176400,604161,614837) kiSS-1 rece ( 398) 411 85.0 4.5e-16
XP_016864182 (OMIM: 606925) PREDICTED: pyroglutamy ( 190) 396 82.0 1.8e-15
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348) 388 80.8 7.1e-15
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384) 388 80.9 7.6e-15
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384) 388 80.9 7.6e-15
XP_011508789 (OMIM: 604153) PREDICTED: neuromedin- ( 403) 388 80.9 7.8e-15
NP_006047 (OMIM: 604153) neuromedin-U receptor 1 [ ( 426) 388 80.9 8.1e-15
NP_620414 (OMIM: 607122) prokineticin receptor 1 [ ( 393) 379 79.3 2.3e-14
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415) 375 78.6 4e-14
NP_006165 (OMIM: 602001) neuropeptide Y receptor t ( 445) 371 77.9 6.8e-14
NP_001304021 (OMIM: 602001) neuropeptide Y recepto ( 445) 371 77.9 6.8e-14
NP_001304020 (OMIM: 602001) neuropeptide Y recepto ( 445) 371 77.9 6.8e-14
XP_005263095 (OMIM: 602001) PREDICTED: neuropeptid ( 445) 371 77.9 6.8e-14
XP_011530319 (OMIM: 602001) PREDICTED: neuropeptid ( 445) 371 77.9 6.8e-14
XP_011530317 (OMIM: 602001) PREDICTED: neuropeptid ( 452) 371 77.9 6.9e-14
XP_016863744 (OMIM: 602001) PREDICTED: neuropeptid ( 452) 371 77.9 6.9e-14
XP_016863745 (OMIM: 602001) PREDICTED: neuropeptid ( 452) 371 77.9 6.9e-14
NP_001116131 (OMIM: 131244,277580,600155,600501) e ( 442) 365 76.9 1.4e-13
NP_000106 (OMIM: 131244,277580,600155,600501) endo ( 442) 365 76.9 1.4e-13
NP_003982 (OMIM: 131244,277580,600155,600501) endo ( 436) 364 76.7 1.6e-13
NP_001188326 (OMIM: 131244,277580,600155,600501) e ( 532) 365 77.0 1.6e-13
>>NP_004876 (OMIM: 607449) neuropeptide FF receptor 2 is (522 aa)
initn: 3526 init1: 3526 opt: 3526 Z-score: 3412.0 bits: 641.0 E(85289): 2.6e-183
Smith-Waterman score: 3526; 100.0% identity (100.0% similar) in 522 aa overlap (1-522:1-522)
10 20 30 40 50 60
pF1KE9 MNSFFGTPAASWCLLESDVSSAPDKEAGRERRALSVQQRGGPAWSGSLEWSRQSAGDRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MNSFFGTPAASWCLLESDVSSAPDKEAGRERRALSVQQRGGPAWSGSLEWSRQSAGDRRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 LGLSRQTAKSSWSRSRDRTCCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LGLSRQTAKSSWSRSRDRTCCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 VNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 VTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 IAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 KTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 QEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 HWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQ
430 440 450 460 470 480
490 500 510 520
pF1KE9 LVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI
::::::::::::::::::::::::::::::::::::::::::
NP_004 LVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI
490 500 510 520
>>NP_001138228 (OMIM: 607449) neuropeptide FF receptor 2 (423 aa)
initn: 2817 init1: 2817 opt: 2817 Z-score: 2729.4 bits: 514.4 E(85289): 2.7e-145
Smith-Waterman score: 2817; 100.0% identity (100.0% similar) in 422 aa overlap (101-522:2-423)
80 90 100 110 120 130
pF1KE9 SWSRSRDRTCCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWNVNDTKHHLYS
::::::::::::::::::::::::::::::
NP_001 MFIMNEKWDTNSSENWHPIWNVNDTKHHLYS
10 20 30
140 150 160 170 180 190
pF1KE9 DINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLA
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE9 ISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVV
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE9 YPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCRE
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE9 DWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRK
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE9 KQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSV
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE9 NPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQNP
340 350 360 370 380 390
500 510 520
pF1KE9 HGETLLYRKSAEKPQQELVMEELKETTNSSEI
::::::::::::::::::::::::::::::::
NP_001 HGETLLYRKSAEKPQQELVMEELKETTNSSEI
400 410 420
>>NP_444264 (OMIM: 607449) neuropeptide FF receptor 2 is (420 aa)
initn: 2804 init1: 2804 opt: 2804 Z-score: 2716.9 bits: 512.0 E(85289): 1.4e-144
Smith-Waterman score: 2804; 100.0% identity (100.0% similar) in 420 aa overlap (103-522:1-420)
80 90 100 110 120 130
pF1KE9 SRSRDRTCCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDI
::::::::::::::::::::::::::::::
NP_444 MNEKWDTNSSENWHPIWNVNDTKHHLYSDI
10 20 30
140 150 160 170 180 190
pF1KE9 NITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 NITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAIS
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE9 DLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 DLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYP
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE9 FKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 FKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDW
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE9 PNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 PNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQ
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE9 KIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 KIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNP
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE9 IIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQNPHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_444 IIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQNPHG
340 350 360 370 380 390
500 510 520
pF1KE9 ETLLYRKSAEKPQQELVMEELKETTNSSEI
::::::::::::::::::::::::::::::
NP_444 ETLLYRKSAEKPQQELVMEELKETTNSSEI
400 410 420
>>XP_011529856 (OMIM: 607449) PREDICTED: neuropeptide FF (304 aa)
initn: 1995 init1: 1995 opt: 1995 Z-score: 1938.4 bits: 367.5 E(85289): 3.1e-101
Smith-Waterman score: 1995; 100.0% identity (100.0% similar) in 304 aa overlap (219-522:1-304)
190 200 210 220 230 240
pF1KE9 LAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQC
::::::::::::::::::::::::::::::
XP_011 MCKISGLVQGISVAASVFTLVAIAVDRFQC
10 20 30
250 260 270 280 290 300
pF1KE9 VVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWC
40 50 60 70 80 90
310 320 330 340 350 360
pF1KE9 REDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REDWPNQEMRKIYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVS
100 110 120 130 140 150
370 380 390 400 410 420
pF1KE9 RKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNS
160 170 180 190 200 210
430 440 450 460 470 480
pF1KE9 SVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQ
220 230 240 250 260 270
490 500 510 520
pF1KE9 NPHGETLLYRKSAEKPQQELVMEELKETTNSSEI
::::::::::::::::::::::::::::::::::
XP_011 NPHGETLLYRKSAEKPQQELVMEELKETTNSSEI
280 290 300
>>NP_071429 (OMIM: 607448) neuropeptide FF receptor 1 [H (430 aa)
initn: 1367 init1: 741 opt: 1381 Z-score: 1344.5 bits: 258.1 E(85289): 3.8e-68
Smith-Waterman score: 1381; 56.4% identity (82.7% similar) in 358 aa overlap (110-466:10-361)
80 90 100 110 120 130
pF1KE9 CCCRRAWWILVPAADRARRERFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYVNY
::: : :. . : :. . :.:. .:
NP_071 MEGEPSQPPNSS--W-PL-SQNGTNTEATPATNLTFSSY
10 20 30
140 150 160 170 180 190
pF1KE9 YLHQPQVAAIFIISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIF
: : :::.::..: :::.:::.:::.:::::..:.:::::::.::::::.::::::::
NP_071 YQHTSPVAAMFIVAYALIFLLCMVGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIF
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE9 CMPITLLDNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTI
::: ::.::.:.:::: :. ::.::::::.::.:::::::::::.::.:.:.::. :::.
NP_071 CMPTTLVDNLITGWPFDNATCKMSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTL
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE9 KTAFVIIMIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRK
. :.: : .::.::. :: :::: : : .:... . ....:.. :.: : : ::.. ::.
NP_071 RKALVTIAVIWALALLIMCPSAVTLTVTREEHHFM-VDARNRSYPLYSCWEAWPEKGMRR
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE9 IYTTVLFANIYLAPLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLL
.::::::..::::::.:::.::.::. .: .: : : .. . .. ::.. ....::.
NP_071 VYTTVLFSHIYLAPLALIVVMYARIARKLCQAPGPAPGGEEAADPRA-SRRRARVVHMLV
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE9 IVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFN
.:::.: :::::::.:..: ::..:: .:.....: .:::::::: :::.::::::.::
NP_071 MVALFFTLSWLPLWALLLLIDYGQLSAPQLHLVTVYAFPFAHWLAFFNSSANPIIYGYFN
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE9 ENFRRGFQEAFQLQLCQK-RAKPMEAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYR
:::::::: ::. .:: . .. :::.
NP_071 ENFRRGFQAAFRARLCPRPSGSHKEAYSERPGGLLHRRVFVVVRPSDSGLPSESGPSSGA
340 350 360 370 380 390
>>NP_937822 (OMIM: 606925) pyroglutamylated RFamide pept (431 aa)
initn: 588 init1: 334 opt: 649 Z-score: 638.6 bits: 127.5 E(85289): 7.8e-29
Smith-Waterman score: 649; 31.5% identity (65.6% similar) in 349 aa overlap (122-463:19-360)
100 110 120 130 140 150
pF1KE9 AADRARRERFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDINITYVNYYLHQPQVAAI-F
: :.... . . . : . : : . .
NP_937 MQALNITPEQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLAL
10 20 30 40
160 170 180 190 200 210
pF1KE9 IISYFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNII
... ::: : ..::..: ..: :.: :.::::.:: .::.::::. .::.:.:.:.::
NP_937 VLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNIS
50 60 70 80 90 100
220 230 240 250 260
pF1KE9 AGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPK--LTIKTAFVIIMI
.: : .::. .::. .:.. ..:.. :::.: : .:.::: : : . ::... .
NP_937 DNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGV
110 120 130 140 150 160
270 280 290 300 310 320
pF1KE9 IWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFAN
.:..:. . :: : :::. . : ... : :.: . .::::: ...
NP_937 VWLVAVIVGSP---MWHVQQLEIKYDFLYEKEHIC----CLEEWTSPVHQKIYTTFILVI
170 180 190 200 210 220
330 340 350 360 370 380
pF1KE9 IYLAPLSLIVIMYGRIGISLF---RAAVPHTGRK-NQEQWHVVSRKKQKIIKMLLIVALL
..: :: ...:.:..:: :. :.. . : . .. ..:::.. . :.. :. :
NP_937 LFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVAL
230 240 250 260 270 280
390 400 410 420 430 440
pF1KE9 FILSWLPLWTLMMLSDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRR
: . : :. .. :. .:... . .. .:. ... ..:.:: :::.:.:.::::..
NP_937 FAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKK
290 300 310 320 330 340
450 460 470 480 490 500
pF1KE9 GFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSAEKP
. : . .: .: .
NP_937 NVLSAVCYCIVNKTFSPAQRHGNSGITMMRKKAKFSLRENPVEETKGEAFSDGNIEVKLC
350 360 370 380 390 400
>>XP_011530312 (OMIM: 162641) PREDICTED: neuropeptide Y (384 aa)
initn: 558 init1: 358 opt: 591 Z-score: 583.3 bits: 117.1 E(85289): 9.5e-26
Smith-Waterman score: 597; 31.5% identity (62.9% similar) in 375 aa overlap (122-486:11-368)
100 110 120 130 140
pF1KE9 AADRARRERFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDIN---ITYVNYYLHQPQVAA
: . : .:. : ... : : : .:
XP_011 MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLP-LAM
10 20 30
150 160 170 180 190 200
pF1KE9 IFIIS--YFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLL
:: .. : ...: . :: .. .:....:.:..:::..:.::..:::::.:.:.:.:..
XP_011 IFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFV
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE9 DNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVII
... : ::..:::.. .:: .:...:.:.:: :::.: : .. : . . . :.: :
XP_011 YTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGI
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE9 MIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLF
.:::::.. : .. . .: . : :.. . : : ...:.. : :::.:.
XP_011 AVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDK---YVCFDQFPSDSHRLSYTTLLL
160 170 180 190 200 210
330 340 350 360 370 380
pF1KE9 ANIYLAPLSLIVIMYGRIGISL-FRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLF
. :..:: .: : : .: : : : . : :. . : . ..: ::: ... :
XP_011 VLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYR----SSETKRINIMLLSIVVAF
220 230 240 250 260 270
390 400 410 420 430 440
pF1KE9 ILSWLPLWTLMMLSDYADLSPNELQIINI----YIYPFAHWLAFGNSSVNPIIYGFFNEN
. :::: . . :. ::: .. . : :. .. ::::.:::.:.:
XP_011 AVCWLPLTIFNTVFDWNH------QIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKN
280 290 300 310 320
450 460 470 480 490 500
pF1KE9 FRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSA
:.: .: : ...:. :.. . : : : . ..:. .....
XP_011 FQRDLQ--FFFNFCDFRSRD-DDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEK
330 340 350 360 370 380
510 520
pF1KE9 EKPQQELVMEELKETTNSSEI
XP_011 I
>>NP_000900 (OMIM: 162641) neuropeptide Y receptor type (384 aa)
initn: 558 init1: 358 opt: 591 Z-score: 583.3 bits: 117.1 E(85289): 9.5e-26
Smith-Waterman score: 597; 31.5% identity (62.9% similar) in 375 aa overlap (122-486:11-368)
100 110 120 130 140
pF1KE9 AADRARRERFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDIN---ITYVNYYLHQPQVAA
: . : .:. : ... : : : .:
NP_000 MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLP-LAM
10 20 30
150 160 170 180 190 200
pF1KE9 IFIIS--YFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLL
:: .. : ...: . :: .. .:....:.:..:::..:.::..:::::.:.:.:.:..
NP_000 IFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFV
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE9 DNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVII
... : ::..:::.. .:: .:...:.:.:: :::.: : .. : . . . :.: :
NP_000 YTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGI
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE9 MIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLF
.:::::.. : .. . .: . : :.. . : : ...:.. : :::.:.
NP_000 AVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDK---YVCFDQFPSDSHRLSYTTLLL
160 170 180 190 200 210
330 340 350 360 370 380
pF1KE9 ANIYLAPLSLIVIMYGRIGISL-FRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLF
. :..:: .: : : .: : : : . : :. . : . ..: ::: ... :
NP_000 VLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYR----SSETKRINIMLLSIVVAF
220 230 240 250 260 270
390 400 410 420 430 440
pF1KE9 ILSWLPLWTLMMLSDYADLSPNELQIINI----YIYPFAHWLAFGNSSVNPIIYGFFNEN
. :::: . . :. ::: .. . : :. .. ::::.:::.:.:
NP_000 AVCWLPLTIFNTVFDWNH------QIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKN
280 290 300 310 320
450 460 470 480 490 500
pF1KE9 FRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSA
:.: .: : ...:. :.. . : : : . ..:. .....
NP_000 FQRDLQ--FFFNFCDFRSRD-DDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEK
330 340 350 360 370 380
510 520
pF1KE9 EKPQQELVMEELKETTNSSEI
NP_000 I
>>XP_005263088 (OMIM: 162641) PREDICTED: neuropeptide Y (384 aa)
initn: 558 init1: 358 opt: 591 Z-score: 583.3 bits: 117.1 E(85289): 9.5e-26
Smith-Waterman score: 597; 31.5% identity (62.9% similar) in 375 aa overlap (122-486:11-368)
100 110 120 130 140
pF1KE9 AADRARRERFIMNEKWDTNSSENWHPIWNVNDTKHHLYSDIN---ITYVNYYLHQPQVAA
: . : .:. : ... : : : .:
XP_005 MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLP-LAM
10 20 30
150 160 170 180 190 200
pF1KE9 IFIIS--YFLIFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLL
:: .. : ...: . :: .. .:....:.:..:::..:.::..:::::.:.:.:.:..
XP_005 IFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFV
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE9 DNIIAGWPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVII
... : ::..:::.. .:: .:...:.:.:: :::.: : .. : . . . :.: :
XP_005 YTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGI
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE9 MIIWVLAITIMSPSAVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLF
.:::::.. : .. . .: . : :.. . : : ...:.. : :::.:.
XP_005 AVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDK---YVCFDQFPSDSHRLSYTTLLL
160 170 180 190 200 210
330 340 350 360 370 380
pF1KE9 ANIYLAPLSLIVIMYGRIGISL-FRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLF
. :..:: .: : : .: : : : . : :. . : . ..: ::: ... :
XP_005 VLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYR----SSETKRINIMLLSIVVAF
220 230 240 250 260 270
390 400 410 420 430 440
pF1KE9 ILSWLPLWTLMMLSDYADLSPNELQIINI----YIYPFAHWLAFGNSSVNPIIYGFFNEN
. :::: . . :. ::: .. . : :. .. ::::.:::.:.:
XP_005 AVCWLPLTIFNTVFDWNH------QIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKN
280 290 300 310 320
450 460 470 480 490 500
pF1KE9 FRRGFQEAFQLQLCQKRAKPMEAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRKSA
:.: .: : ...:. :.. . : : : . ..:. .....
XP_005 FQRDLQ--FFFNFCDFRSRD-DDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEK
330 340 350 360 370 380
510 520
pF1KE9 EKPQQELVMEELKETTNSSEI
XP_005 I
>>NP_057624 (OMIM: 605569) probable G-protein coupled re (423 aa)
initn: 620 init1: 404 opt: 545 Z-score: 538.4 bits: 109.0 E(85289): 3e-23
Smith-Waterman score: 657; 33.3% identity (66.7% similar) in 324 aa overlap (142-463:66-371)
120 130 140 150 160 170
pF1KE9 SENWHPIWNVNDTKHHLYSDINITYVNYYLHQPQVAAIFIISYFLIFFLCMMGNTVVCFI
..: : :..:..: .:. . ..::..:: .
NP_057 PNASHFFSWNNYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHV
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE9 VMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMCKISGLVQGISV
...:..::..:.:::.:::..:... .. :.::. . . : ::. ::..: ..: :.
NP_057 IFKNQRMHSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSL
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE9 AASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEEKY
.:..::.:::::: : ...:.::...: . . : .::..: . : :. .. ::
NP_057 HVSALTLTAIAVDRHQVIMHPLKPRISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKY
160 170 180 190 200 210
300 310 320 330 340
pF1KE9 YRVRLNSQNKTSPVYWCREDWPNQE--MRKIYTTVLFANIYLAPLSLIVIMYGRIGISLF
:.. . . : :.:. . : . : .:. :: .: . :.:.. .:.
NP_057 ------SEDIVRSL--CLPDFPEPADLFWKYLDLATFILLYILPLLIISVAYARVAKKLW
220 230 240 250 260
350 360 370 380 390 400
pF1KE9 RAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYADLSPNEL
. : . ::. .. :::.: ::::..:..:: : :.:: ..: :: . .
NP_057 LCNM--IGDVTTEQYFALRRKKKKTIKMLMLVVVLFALCWFPLNCYVLL-----LSSKVI
270 280 290 300 310 320
410 420 430 440 450 460
pF1KE9 QIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRAKPMEAYALKA
. : . : ::.:.... ::.:: ..::::: .. :..::. ::.:
NP_057 RTNNALYFAF-HWFAMSSTCYNPFIYCWLNENFR--IELKALLSMCQRPPKPQEDRPPSP
330 340 350 360 370
470 480 490 500 510 520
pF1KE9 KSHVLINTSNQLVQESTFQNPHGETLLYRKSAEKPQQELVMEELKETTNSSEI
NP_057 VPSFRVAWTEKNDGQRAPLANNLLPTSQLQSGKTDLSSVEPIVTMS
380 390 400 410 420
522 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 17:28:46 2016 done: Sun Nov 6 17:28:47 2016
Total Scan time: 8.740 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]