Result of FASTA (omim) for
pFN21AE5273
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5273, 178 aa
1>>>pF1KE5273 178 - 178 aa - 178 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6314+/-0.000344; mu= 16.2872+/- 0.021
mean_var=59.0792+/-11.697, 0's: 0 Z-trim(114.2): 31 B-trim: 0 in 0/51
Lambda= 0.166862
statistics sampled from 23949 (23981) to 23949 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.281), width: 16
Scan time: 5.220
The best scores are: opt bits E(85289)
NP_060011 (OMIM: 116100,123730) beta-crystallin S ( 178) 1277 315.3 3.2e-86
NP_005201 (OMIM: 123670,615188) gamma-crystallin B ( 175) 734 184.6 7.1e-47
XP_016858891 (OMIM: 123670,615188) PREDICTED: gamm ( 177) 724 182.2 3.8e-46
XP_011508964 (OMIM: 123680,604307) PREDICTED: gamm ( 174) 698 175.9 2.9e-44
NP_066269 (OMIM: 123680,604307) gamma-crystallin C ( 174) 698 175.9 2.9e-44
NP_055432 (OMIM: 123660) gamma-crystallin A [Homo ( 174) 682 172.1 4.2e-43
NP_008822 (OMIM: 115700,123690) gamma-crystallin D ( 174) 660 166.8 1.6e-41
XP_011514138 (OMIM: 609603) PREDICTED: gamma-cryst ( 295) 473 121.9 8.7e-28
XP_005250009 (OMIM: 609603) PREDICTED: gamma-cryst ( 182) 468 120.6 1.4e-27
NP_004067 (OMIM: 123630,609741) beta-crystallin B3 ( 211) 417 108.4 7.7e-24
XP_011528204 (OMIM: 123630,609741) PREDICTED: beta ( 267) 417 108.4 9.2e-24
XP_011528201 (OMIM: 600929,611544) PREDICTED: beta ( 252) 415 107.9 1.2e-23
NP_001878 (OMIM: 600929,611544) beta-crystallin B1 ( 252) 415 107.9 1.2e-23
XP_011528202 (OMIM: 123620,601547) PREDICTED: beta ( 205) 406 105.7 4.7e-23
XP_006724204 (OMIM: 123620,601547) PREDICTED: beta ( 205) 406 105.7 4.7e-23
NP_000487 (OMIM: 123620,601547) beta-crystallin B2 ( 205) 406 105.7 4.7e-23
XP_011514139 (OMIM: 609603) PREDICTED: gamma-cryst ( 260) 399 104.1 1.8e-22
NP_005199 (OMIM: 123610,600881) beta-crystallin A3 ( 215) 370 97.0 2e-20
XP_016879687 (OMIM: 123610,600881) PREDICTED: beta ( 316) 370 97.2 2.7e-20
NP_476435 (OMIM: 115900,600836) beta-crystallin A2 ( 197) 348 91.7 7.3e-19
NP_476434 (OMIM: 115900,600836) beta-crystallin A2 ( 197) 348 91.7 7.3e-19
NP_653328 (OMIM: 609603) gamma-crystallin N isofor ( 182) 334 88.3 7.1e-18
NP_001877 (OMIM: 123631,610425) beta-crystallin A4 ( 196) 303 80.9 1.3e-15
XP_006724203 (OMIM: 123631,610425) PREDICTED: beta ( 201) 303 80.9 1.4e-15
XP_016884087 (OMIM: 123631,610425) PREDICTED: beta ( 207) 303 80.9 1.4e-15
XP_016867262 (OMIM: 609603) PREDICTED: gamma-cryst ( 125) 291 77.9 7e-15
NP_001295221 (OMIM: 609603) gamma-crystallin N iso ( 125) 291 77.9 7e-15
XP_016865822 (OMIM: 601797) PREDICTED: absent in m (1544) 293 79.2 3.5e-14
NP_001615 (OMIM: 601797) absent in melanoma 1 prot (1723) 255 70.0 2.1e-11
XP_005266896 (OMIM: 601797) PREDICTED: absent in m (2131) 255 70.1 2.5e-11
XP_016884088 (OMIM: 123630,609741) PREDICTED: beta ( 169) 187 52.9 3e-07
>>NP_060011 (OMIM: 116100,123730) beta-crystallin S [Hom (178 aa)
initn: 1277 init1: 1277 opt: 1277 Z-score: 1668.9 bits: 315.3 E(85289): 3.2e-86
Smith-Waterman score: 1277; 100.0% identity (100.0% similar) in 178 aa overlap (1-178:1-178)
10 20 30 40 50 60
pF1KE5 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIME
70 80 90 100 110 120
130 140 150 160 170
pF1KE5 QFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE
130 140 150 160 170
>>NP_005201 (OMIM: 123670,615188) gamma-crystallin B [Ho (175 aa)
initn: 693 init1: 388 opt: 734 Z-score: 962.5 bits: 184.6 E(85289): 7.1e-47
Smith-Waterman score: 734; 54.7% identity (80.2% similar) in 172 aa overlap (7-178:3-173)
10 20 30 40 50 60
pF1KE5 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMY
:::::::. :::: :.: :: ... :.::::::.::.: : .:::::. :..:
NP_005 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQY
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 ILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIME
.: .::::.::.::::.: . :: . : .: :...:... .. ::: : :.:: :...
NP_005 FLRRGEYPDYQQWMGLSDSIRSCCLIP-PHSGAYRMKIYDRDELRGQMSELTDDCISVQD
60 70 80 90 100 110
130 140 150 160 170
pF1KE5 QFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE
.::. :::: .:::: ::.::.:::::::::: :::. .:::: . : :.::...
NP_005 RFHLTEIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
120 130 140 150 160 170
>>XP_016858891 (OMIM: 123670,615188) PREDICTED: gamma-cr (177 aa)
initn: 690 init1: 385 opt: 724 Z-score: 949.4 bits: 182.2 E(85289): 3.8e-46
Smith-Waterman score: 724; 53.8% identity (79.8% similar) in 173 aa overlap (7-178:3-175)
10 20 30 40 50 60
pF1KE5 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMY
:::::::. :::: :.: :: ... :.::::::.::.: : .:::::. :..:
XP_016 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQY
10 20 30 40 50
70 80 90 100 110
pF1KE5 ILPQGEYPEYQRWMGLNDRLSSCRAVH-LPSGGQYKIQIFEKGDFSGQMYETTEDCPSIM
.: .::::.::.::::.: . :: . . .: :...:... .. ::: : :.:: :..
XP_016 FLRRGEYPDYQQWMGLSDSIRSCCLIPPVSHSGAYRMKIYDRDELRGQMSELTDDCISVQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE5 EQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE
..::. :::: .:::: ::.::.:::::::::: :::. .:::: . : :.::...
XP_016 DRFHLTEIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDL
120 130 140 150 160 170
XP_016 Y
>>XP_011508964 (OMIM: 123680,604307) PREDICTED: gamma-cr (174 aa)
initn: 649 init1: 367 opt: 698 Z-score: 915.7 bits: 175.9 E(85289): 2.9e-44
Smith-Waterman score: 698; 53.5% identity (79.7% similar) in 172 aa overlap (7-178:3-172)
10 20 30 40 50 60
pF1KE5 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMY
:::::::. :::: :. :: ... :.::::::.::.: : .:::::. : .:
XP_011 MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQY
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 ILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIME
.: .::::.::.::::.: . :: . :. .......:. : .: :.: .::::::..
XP_011 LLRRGEYPDYQQWMGLSDSIRSCCLI--PQTVSHRLRLYEREDHKGLMMELSEDCPSIQD
60 70 80 90 100 110
130 140 150 160 170
pF1KE5 QFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE
.::. ::.: .:::: :..::::::::::::: .:::. :::: . . :.::.:.
XP_011 RFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY
120 130 140 150 160 170
>>NP_066269 (OMIM: 123680,604307) gamma-crystallin C [Ho (174 aa)
initn: 649 init1: 367 opt: 698 Z-score: 915.7 bits: 175.9 E(85289): 2.9e-44
Smith-Waterman score: 698; 53.5% identity (79.7% similar) in 172 aa overlap (7-178:3-172)
10 20 30 40 50 60
pF1KE5 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMY
:::::::. :::: :. :: ... :.::::::.::.: : .:::::. : .:
NP_066 MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQY
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 ILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIME
.: .::::.::.::::.: . :: . :. .......:. : .: :.: .::::::..
NP_066 LLRRGEYPDYQQWMGLSDSIRSCCLI--PQTVSHRLRLYEREDHKGLMMELSEDCPSIQD
60 70 80 90 100 110
130 140 150 160 170
pF1KE5 QFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE
.::. ::.: .:::: :..::::::::::::: .:::. :::: . . :.::.:.
NP_066 RFHLSEIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY
120 130 140 150 160 170
>>NP_055432 (OMIM: 123660) gamma-crystallin A [Homo sapi (174 aa)
initn: 791 init1: 379 opt: 682 Z-score: 894.9 bits: 172.1 E(85289): 4.2e-43
Smith-Waterman score: 682; 51.2% identity (80.2% similar) in 172 aa overlap (7-178:3-172)
10 20 30 40 50 60
pF1KE5 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMY
:::::::..:::: :.: :: ....:.::::::.:..: : .:::::. :..:
NP_055 MGKITFYEDRDFQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQY
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 ILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIME
.: .:.::.::.::::.: ..::: . : ...:....:. :. : : : :.:: . :
NP_055 FLRRGKYPDYQHWMGLSDSVQSCRII--PHTSSHKLRLYERDDYRGLMSELTDDCACVPE
60 70 80 90 100 110
130 140 150 160 170
pF1KE5 QFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE
:.. ::.: .:::: :..::.:::::::::: .::. :::.:. : :.::...
NP_055 LFRLPEIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTDLY
120 130 140 150 160 170
>>NP_008822 (OMIM: 115700,123690) gamma-crystallin D [Ho (174 aa)
initn: 761 init1: 336 opt: 660 Z-score: 866.3 bits: 166.8 E(85289): 1.6e-41
Smith-Waterman score: 660; 50.0% identity (80.2% similar) in 172 aa overlap (7-178:3-172)
10 20 30 40 50 60
pF1KE5 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMY
:::.:::..::::.:.:. : ... ::::::: .:..: : .::.::..: .:
NP_008 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQY
10 20 30 40 50
70 80 90 100 110 120
pF1KE5 ILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIME
.: .:.: ..:.::::.: . ::: . : .:...:...:. :. ::: : :::: ...
NP_008 FLRRGDYADHQQWMGLSDSVRSCRLI--PHSGSHRIRLYEREDYRGQMIEFTEDCSCLQD
60 70 80 90 100 110
130 140 150 160 170
pF1KE5 QFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE
.:.. :::: .:::: :..::: ::::::::: .::. ::::.. : :.::...
NP_008 RFRFNEIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVIDFS
120 130 140 150 160 170
>>XP_011514138 (OMIM: 609603) PREDICTED: gamma-crystalli (295 aa)
initn: 371 init1: 213 opt: 473 Z-score: 619.8 bits: 121.9 E(85289): 8.7e-28
Smith-Waterman score: 473; 37.0% identity (73.5% similar) in 181 aa overlap (1-177:1-180)
10 20 30 40 50
pF1KE5 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHT--YLSRCNSIKVEGGTWAVYERPNFAGY
:.. . :::.:: :.: :.. . :: .:. ...: :::.::.:.:. ...:.: :
XP_011 MAQRSGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 MYILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSI
..:: .:.::.. :: . .:...::: : . : .....::: .:.:: : :: : .
XP_011 QFILEHGDYPDFFRWNSHSDHMGSCRPVGM-HGEHFRLEIFEGCNFTGQCLEFLEDSPFL
70 80 90 100 110
120 130 140 150 160 170
pF1KE5 MEQFHMRE-IHSCKVL-EGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRI
. . ... ... :: .:.:..:: :::.::.:.... ..:. :: : : :::....
XP_011 QSRGWVKNCVNTIKVYGDGAWVLYEEPNYHGRMYVVESGDFRSFSDWEAHSARVQSLHKV
120 130 140 150 160 170
pF1KE5 VE
:
XP_011 VNFFQPSPPTGMAGRSSGDRGNPLRSHPDLGTLGDKSPQSQRAASECSLGSGHPSPGRSW
180 190 200 210 220 230
>>XP_005250009 (OMIM: 609603) PREDICTED: gamma-crystalli (182 aa)
initn: 366 init1: 213 opt: 468 Z-score: 616.2 bits: 120.6 E(85289): 1.4e-27
Smith-Waterman score: 468; 36.8% identity (73.1% similar) in 182 aa overlap (1-178:1-181)
10 20 30 40 50
pF1KE5 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHT--YLSRCNSIKVEGGTWAVYERPNFAGY
:.. . :::.:: :.: :.. . :: .:. ...: :::.::.:.:. ...:.: :
XP_005 MAQRSGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 MYILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSI
..:: .:.::.. :: . .:...::: : . : .....::: .:.:: : :: : .
XP_005 QFILEHGDYPDFFRWNSHSDHMGSCRPVGM-HGEHFRLEIFEGCNFTGQCLEFLEDSPFL
70 80 90 100 110
120 130 140 150 160 170
pF1KE5 MEQFHMRE-IHSCKVL-EGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRI
. . ... ... :: .:.:..:: :::.::.:.... ..:. :: : : :::...
XP_005 QSRGWVKNCVNTIKVYGDGAWVLYEEPNYHGRMYVVESGDFRSFSDWEAHSARVQSLHKS
120 130 140 150 160 170
pF1KE5 VE
.:
XP_005 MEP
180
>>NP_004067 (OMIM: 123630,609741) beta-crystallin B3 [Ho (211 aa)
initn: 354 init1: 203 opt: 417 Z-score: 549.0 bits: 108.4 E(85289): 7.7e-24
Smith-Waterman score: 417; 35.6% identity (70.7% similar) in 174 aa overlap (7-176:25-197)
10 20 30 40
pF1KE5 MSKTGTKITFYEDKNFQGRRYDCDCDCADF-HTYLSRCNSIK
:. .:: .::::.: . . .: .. . : . .::.
NP_004 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
10 20 30 40 50 60
50 60 70 80 90
pF1KE5 VEGGTWAVYERPNFAGYMYILPQGEYPEYQRWMGL--NDRLSSCRAVHLPSGGQYKIQIF
::.: : ..: : : ...: .:.::... : . .: : : : ... : ..:...:
NP_004 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSP-HHKLHLF
70 80 90 100 110
100 110 120 130 140 150
pF1KE5 EKGDFSGQMYETTED-CPSIMEQFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYR
:. :::. .: ..: ::. . . .. : ....:.:. ::.:.::::::.... :::
NP_004 ENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYR
120 130 140 150 160 170
160 170
pF1KE5 KPIDWGAASPAVQSFRRIVE
. .: :..: .:: :::
NP_004 HWNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
180 190 200 210
178 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 23:19:47 2016 done: Mon Nov 7 23:19:48 2016
Total Scan time: 5.220 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]