Result of FASTA (omim) for
pFN21AE6528
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6528, 175 aa
1>>>pF1KE6528 175 - 175 aa - 175 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0509+/-0.000316; mu= 13.8978+/- 0.020
mean_var=65.8934+/-12.985, 0's: 0 Z-trim(116.5): 31 B-trim: 30 in 1/51
Lambda= 0.157999
statistics sampled from 27673 (27704) to 27673 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.325), width: 16
Scan time: 4.370
The best scores are: opt bits E(85289)
NP_005201 (OMIM: 123670,615188) gamma-crystallin B ( 175) 1264 296.4 1.6e-80
XP_016858891 (OMIM: 123670,615188) PREDICTED: gamm ( 177) 1250 293.2 1.5e-79
XP_011508964 (OMIM: 123680,604307) PREDICTED: gamm ( 174) 1019 240.5 1e-63
NP_066269 (OMIM: 123680,604307) gamma-crystallin C ( 174) 1019 240.5 1e-63
NP_055432 (OMIM: 123660) gamma-crystallin A [Homo ( 174) 974 230.3 1.3e-60
NP_008822 (OMIM: 115700,123690) gamma-crystallin D ( 174) 951 225.0 4.8e-59
NP_060011 (OMIM: 116100,123730) beta-crystallin S ( 178) 733 175.3 4.4e-44
XP_011514138 (OMIM: 609603) PREDICTED: gamma-cryst ( 295) 474 116.4 3.9e-26
XP_005250009 (OMIM: 609603) PREDICTED: gamma-cryst ( 182) 468 114.9 6.9e-26
XP_006724204 (OMIM: 123620,601547) PREDICTED: beta ( 205) 395 98.3 7.7e-21
NP_000487 (OMIM: 123620,601547) beta-crystallin B2 ( 205) 395 98.3 7.7e-21
XP_011528202 (OMIM: 123620,601547) PREDICTED: beta ( 205) 395 98.3 7.7e-21
XP_011514139 (OMIM: 609603) PREDICTED: gamma-cryst ( 260) 395 98.4 9.3e-21
NP_004067 (OMIM: 123630,609741) beta-crystallin B3 ( 211) 384 95.8 4.5e-20
XP_011528204 (OMIM: 123630,609741) PREDICTED: beta ( 267) 384 95.9 5.4e-20
XP_011528201 (OMIM: 600929,611544) PREDICTED: beta ( 252) 369 92.5 5.5e-19
NP_001878 (OMIM: 600929,611544) beta-crystallin B1 ( 252) 369 92.5 5.5e-19
NP_005199 (OMIM: 123610,600881) beta-crystallin A3 ( 215) 347 87.4 1.6e-17
XP_016879687 (OMIM: 123610,600881) PREDICTED: beta ( 316) 347 87.5 2.1e-17
NP_001877 (OMIM: 123631,610425) beta-crystallin A4 ( 196) 322 81.7 7.6e-16
XP_006724203 (OMIM: 123631,610425) PREDICTED: beta ( 201) 322 81.7 7.7e-16
XP_016884087 (OMIM: 123631,610425) PREDICTED: beta ( 207) 322 81.7 7.9e-16
XP_016865822 (OMIM: 601797) PREDICTED: absent in m (1544) 322 82.3 3.9e-15
NP_001615 (OMIM: 601797) absent in melanoma 1 prot (1723) 322 82.3 4.3e-15
NP_653328 (OMIM: 609603) gamma-crystallin N isofor ( 182) 310 78.9 4.8e-15
NP_476434 (OMIM: 115900,600836) beta-crystallin A2 ( 197) 310 78.9 5.1e-15
NP_476435 (OMIM: 115900,600836) beta-crystallin A2 ( 197) 310 78.9 5.1e-15
XP_005266896 (OMIM: 601797) PREDICTED: absent in m (2131) 322 82.4 5.1e-15
NP_001295221 (OMIM: 609603) gamma-crystallin N iso ( 125) 208 55.6 3.5e-08
XP_016867262 (OMIM: 609603) PREDICTED: gamma-cryst ( 125) 208 55.6 3.5e-08
XP_016884088 (OMIM: 123630,609741) PREDICTED: beta ( 169) 199 53.6 1.9e-07
>>NP_005201 (OMIM: 123670,615188) gamma-crystallin B [Ho (175 aa)
initn: 1264 init1: 1264 opt: 1264 Z-score: 1566.6 bits: 296.4 E(85289): 1.6e-80
Smith-Waterman score: 1264; 99.4% identity (100.0% similar) in 175 aa overlap (1-175:1-175)
10 20 30 40 50 60
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCLSVQDRFHLT
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
NP_005 GEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCISVQDRFHLT
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 EIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
130 140 150 160 170
>>XP_016858891 (OMIM: 123670,615188) PREDICTED: gamma-cr (177 aa)
initn: 1272 init1: 636 opt: 1250 Z-score: 1549.3 bits: 293.2 E(85289): 1.5e-79
Smith-Waterman score: 1250; 98.3% identity (98.9% similar) in 177 aa overlap (1-175:1-177)
10 20 30 40 50 60
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR
10 20 30 40 50 60
70 80 90 100 110
pF1KE6 GEYPDYQQWMGLSDSIRSCCLIPP--HSGAYRMKIYDRDELRGQMSELTDDCLSVQDRFH
:::::::::::::::::::::::: ::::::::::::::::::::::::::.:::::::
XP_016 GEYPDYQQWMGLSDSIRSCCLIPPVSHSGAYRMKIYDRDELRGQMSELTDDCISVQDRFH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 LTEIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTEIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
130 140 150 160 170
>>XP_011508964 (OMIM: 123680,604307) PREDICTED: gamma-cr (174 aa)
initn: 592 init1: 592 opt: 1019 Z-score: 1264.9 bits: 240.5 E(85289): 1e-63
Smith-Waterman score: 1019; 78.9% identity (93.1% similar) in 175 aa overlap (1-175:1-174)
10 20 30 40 50 60
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR
:::::::::::::::::: :::::::::::::::::::::::::.::::::::.::.:::
XP_011 MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCLSVQDRFHLT
::::::::::::::::::::::: .. ..:...:.:.. .: : ::..:: :.::::::.
XP_011 GEYPDYQQWMGLSDSIRSCCLIP-QTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLS
70 80 90 100 110
130 140 150 160 170
pF1KE6 EIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
::.::.:::: :.:::.:::::::::::: :::: :::: .::.::::::.:::
XP_011 EIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY
120 130 140 150 160 170
>>NP_066269 (OMIM: 123680,604307) gamma-crystallin C [Ho (174 aa)
initn: 592 init1: 592 opt: 1019 Z-score: 1264.9 bits: 240.5 E(85289): 1e-63
Smith-Waterman score: 1019; 78.9% identity (93.1% similar) in 175 aa overlap (1-175:1-174)
10 20 30 40 50 60
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR
:::::::::::::::::: :::::::::::::::::::::::::.::::::::.::.:::
NP_066 MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCLSVQDRFHLT
::::::::::::::::::::::: .. ..:...:.:.. .: : ::..:: :.::::::.
NP_066 GEYPDYQQWMGLSDSIRSCCLIP-QTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLS
70 80 90 100 110
130 140 150 160 170
pF1KE6 EIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
::.::.:::: :.:::.:::::::::::: :::: :::: .::.::::::.:::
NP_066 EIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY
120 130 140 150 160 170
>>NP_055432 (OMIM: 123660) gamma-crystallin A [Homo sapi (174 aa)
initn: 561 init1: 534 opt: 974 Z-score: 1209.4 bits: 230.3 E(85289): 1.3e-60
Smith-Waterman score: 974; 73.7% identity (90.3% similar) in 175 aa overlap (1-175:1-174)
10 20 30 40 50 60
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR
:::::::::: :::: :.: .:::::. ::::::::::.:::::.:::::::::::::::
NP_055 MGKITFYEDRDFQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCLSVQDRFHLT
:.:::::.:::::::..:: .:: :........:.::. :: :::::::: : . :.:
NP_055 GKYPDYQHWMGLSDSVQSCRIIP-HTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLP
70 80 90 100 110
130 140 150 160 170
pF1KE6 EIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
::.::.:::: :.:::::::::::::::::.:::. :::. .::::::::: :::
NP_055 EIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTDLY
120 130 140 150 160 170
>>NP_008822 (OMIM: 115700,123690) gamma-crystallin D [Ho (174 aa)
initn: 987 init1: 500 opt: 951 Z-score: 1181.1 bits: 225.0 E(85289): 4.8e-59
Smith-Waterman score: 951; 72.4% identity (91.4% similar) in 174 aa overlap (1-174:1-173)
10 20 30 40 50 60
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR
:::::.::::.:::: :::..: ::::::.::::: ::.:::::.::.:::.: ::::::
NP_008 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCLSVQDRFHLT
:.: :.:::::::::.::: ::: :::..:...:.:.. :::: :.:.:: .::::...
NP_008 GDYADHQQWMGLSDSVRSCRLIP-HSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFN
70 80 90 100 110
130 140 150 160 170
pF1KE6 EIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
::::::::::::.:::. ::::::::: ::.:::. :::: ::.:::::::.:.
NP_008 EIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVIDFS
120 130 140 150 160 170
>>NP_060011 (OMIM: 116100,123730) beta-crystallin S [Hom (178 aa)
initn: 692 init1: 388 opt: 733 Z-score: 912.4 bits: 175.3 E(85289): 4.4e-44
Smith-Waterman score: 733; 54.7% identity (80.2% similar) in 172 aa overlap (3-173:7-178)
10 20 30 40 50
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQY
:::::::. :::: :.: :: ... :.::::::.::.: : .:::::. :..:
NP_060 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 FLRRGEYPDYQQWMGLSDSIRSCCLIP-PHSGAYRMKIYDRDELRGQMSELTDDCLSVQD
.: .::::.::.::::.: . :: . : .: :...:... .. ::: : :.:: :...
NP_060 ILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIME
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 RFHLTEIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
.::. :::: .:::: ::.::.:::::::::: :::. .:::: . : :.::...
NP_060 QFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE
130 140 150 160 170
>>XP_011514138 (OMIM: 609603) PREDICTED: gamma-crystalli (295 aa)
initn: 431 init1: 217 opt: 474 Z-score: 590.2 bits: 116.4 E(85289): 3.9e-26
Smith-Waterman score: 474; 37.6% identity (73.6% similar) in 178 aa overlap (2-175:6-183)
10 20 30 40 50
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQP--YFSRCNSIRVESGCWMIYERPNYQGH
::::.:: . : :.. : :: :.: ...: :::.:::: :. ...:...:.
XP_011 MAQRSGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 QYFLRRGEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCLSVQ
:..:..:.:::. .: . :: . :: . :. .:..:.. .. :: :. .: .:
XP_011 QFILEHGDYPDFFRWNSHSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 DRFHLTE-IHSLNVL-EGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVM
.: . . .....: .:.:.::: :::.::.:... :..: : :: : .:.: ::..:.
XP_011 SRGWVKNCVNTIKVYGDGAWVLYEEPNYHGRMYVVESGDFRSFSDWEAHSARVQSLHKVV
130 140 150 160 170 180
pF1KE6 DLY
...
XP_011 NFFQPSPPTGMAGRSSGDRGNPLRSHPDLGTLGDKSPQSQRAASECSLGSGHPSPGRSWM
190 200 210 220 230 240
>>XP_005250009 (OMIM: 609603) PREDICTED: gamma-crystalli (182 aa)
initn: 425 init1: 217 opt: 468 Z-score: 585.8 bits: 114.9 E(85289): 6.9e-26
Smith-Waterman score: 468; 38.1% identity (72.7% similar) in 176 aa overlap (2-173:6-181)
10 20 30 40 50
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQP--YFSRCNSIRVESGCWMIYERPNYQGH
::::.:: . : :.. : :: :.: ...: :::.:::: :. ...:...:.
XP_005 MAQRSGKITLYEGKHFTGQKLEVFGDCDNFQDRGFMNRVNSIHVESGAWVCFNHPDFRGQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 QYFLRRGEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCLSVQ
:..:..:.:::. .: . :: . :: . :. .:..:.. .. :: :. .: .:
XP_005 QFILEHGDYPDFFRWNSHSDHMGSCRPVGMHGEHFRLEIFEGCNFTGQCLEFLEDSPFLQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 DRFHLTE-IHSLNVL-EGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVM
.: . . .....: .:.:.::: :::.::.:... :..: : :: : .:.: ::.. :
XP_005 SRGWVKNCVNTIKVYGDGAWVLYEEPNYHGRMYVVESGDFRSFSDWEAHSARVQSLHKSM
130 140 150 160 170 180
pF1KE6 DLY
.
XP_005 EP
>>XP_006724204 (OMIM: 123620,601547) PREDICTED: beta-cry (205 aa)
initn: 417 init1: 192 opt: 395 Z-score: 495.1 bits: 98.3 E(85289): 7.7e-21
Smith-Waterman score: 395; 34.7% identity (67.0% similar) in 176 aa overlap (3-174:18-193)
10 20 30 40
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQPY-FSRCNSIRVESGCWM
:: ..:.. :::.:.: . ::::. . .:. :..: :.
XP_006 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 IYERPNYQGHQYFLRRGEYPDYQQWMGL--SDSIRSCCLIPPHSGAYRMKIYDRDELRGQ
::. : .:.:. ...:::: ...: . .::. : : : ... .:. .. :.
XP_006 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE6 MSELTDDCL-SVQDRFHLTEIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAP
:. :: . : . . . .. :. : :.:. :..:.::: ::::. :.:. :.:::
XP_006 KMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAP
130 140 150 160 170 180
170
pF1KE6 NAKVGSLRRVMDLY
. .: :.::. :.
XP_006 HPQVQSVRRIRDMQWHQRGAFHPSN
190 200
175 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 14:07:47 2016 done: Tue Nov 8 14:07:48 2016
Total Scan time: 4.370 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]