Result of FASTA (ccds) for
pFN21AE6527
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6527, 174 aa
1>>>pF1KE6527 174 - 174 aa - 174 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0881+/-0.000711; mu= 13.4934+/- 0.043
mean_var=57.1407+/-11.543, 0's: 0 Z-trim(108.1): 22 B-trim: 50 in 1/50
Lambda= 0.169669
statistics sampled from 9950 (9971) to 9950 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.697), E-opt: 0.2 (0.306), width: 16
Scan time: 1.160
The best scores are: opt bits E(32554)
CCDS2378.1 CRYGD gene_id:1421|Hs108|chr2 ( 174) 1248 313.2 5.2e-86
CCDS2380.1 CRYGB gene_id:1419|Hs108|chr2 ( 175) 951 240.5 4e-64
CCDS33367.1 CRYGA gene_id:1418|Hs108|chr2 ( 174) 931 235.6 1.2e-62
CCDS2379.1 CRYGC gene_id:1420|Hs108|chr2 ( 174) 920 232.9 7.7e-62
CCDS3275.1 CRYGS gene_id:1427|Hs108|chr3 ( 178) 660 169.3 1.1e-42
CCDS11249.1 CRYBA1 gene_id:1411|Hs108|chr17 ( 215) 363 96.6 1e-20
CCDS13830.1 CRYBB3 gene_id:1417|Hs108|chr22 ( 211) 360 95.9 1.7e-20
CCDS13840.1 CRYBB1 gene_id:1414|Hs108|chr22 ( 252) 357 95.2 3.2e-20
CCDS13831.1 CRYBB2 gene_id:1415|Hs108|chr22 ( 205) 348 92.9 1.2e-19
CCDS34506.1 AIM1 gene_id:202|Hs108|chr6 (1723) 276 75.7 1.6e-13
>>CCDS2378.1 CRYGD gene_id:1421|Hs108|chr2 (174 aa)
initn: 1248 init1: 1248 opt: 1248 Z-score: 1657.6 bits: 313.2 E(32554): 5.2e-86
Smith-Waterman score: 1248; 100.0% identity (100.0% similar) in 174 aa overlap (1-174:1-174)
10 20 30 40 50 60
pF1KE6 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GDYADHQQWMGLSDSVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 GDYADHQQWMGLSDSVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNE
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 IHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVIDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 IHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVIDFS
130 140 150 160 170
>>CCDS2380.1 CRYGB gene_id:1419|Hs108|chr2 (175 aa)
initn: 987 init1: 500 opt: 951 Z-score: 1264.7 bits: 240.5 E(32554): 4e-64
Smith-Waterman score: 951; 72.4% identity (91.4% similar) in 174 aa overlap (1-173:1-174)
10 20 30 40 50 60
pF1KE6 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRR
:::::.::::.:::: :::..: ::::::.::::: ::.:::::.::.:::.: ::::::
CCDS23 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR
10 20 30 40 50 60
70 80 90 100 110
pF1KE6 GDYADHQQWMGLSDSVRSCRLIP-HSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFN
:.: :.:::::::::.::: ::: :::..:...:.:.. :::: :.:.:: .::::...
CCDS23 GEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCISVQDRFHLT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 EIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVIDFS
::::::::::::.:::. ::::::::: ::.:::. :::: ::.:::::::.:.
CCDS23 EIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
130 140 150 160 170
>>CCDS33367.1 CRYGA gene_id:1418|Hs108|chr2 (174 aa)
initn: 1079 init1: 931 opt: 931 Z-score: 1238.3 bits: 235.6 E(32554): 1.2e-62
Smith-Waterman score: 931; 72.3% identity (89.6% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KE6 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRR
:::::.:::: :::: :.: :: :::. :.::::: :::::::::::.:::.: ::::::
CCDS33 MGKITFYEDRDFQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GDYADHQQWMGLSDSVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNE
: : :.:.::::::::.:::.:::..::..:::::.:::: : :.:.::.:. . ::. :
CCDS33 GKYPDYQHWMGLSDSVQSCRIIPHTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLPE
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 IHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVIDFS
:.::.:::: :::::. ::::::::: :::::::.:::...:.::::::: :.
CCDS33 IYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTDLY
130 140 150 160 170
>>CCDS2379.1 CRYGC gene_id:1420|Hs108|chr2 (174 aa)
initn: 1060 init1: 920 opt: 920 Z-score: 1223.7 bits: 232.9 E(32554): 7.7e-62
Smith-Waterman score: 920; 71.7% identity (90.2% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KE6 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRR
:::::.::::.:::: :: ..: ::::::.::::: ::.::::::::.:::.: ::.:::
CCDS23 MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GDYADHQQWMGLSDSVRSCRLIPHSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFNE
:.: :.:::::::::.::: :::.. :::.:::::::..: :.:..::: .::::...:
CCDS23 GEYPDYQQWMGLSDSIRSCCLIPQTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLSE
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 IHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVIDFS
:.::.:::: :::::: ::::::::: : .::: ::::: .:..::::::.:.
CCDS23 IRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY
130 140 150 160 170
>>CCDS3275.1 CRYGS gene_id:1427|Hs108|chr3 (178 aa)
initn: 761 init1: 336 opt: 660 Z-score: 879.6 bits: 169.3 E(32554): 1.1e-42
Smith-Waterman score: 660; 50.0% identity (80.2% similar) in 172 aa overlap (3-172:7-178)
10 20 30 40 50
pF1KE6 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQY
:::.:::..::::.:.:. : ... ::::::: .:..: : .::.::..: .:
CCDS32 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 FLRRGDYADHQQWMGLSDSVRSCRLI--PHSGSHRIRLYEREDYRGQMIEFTEDCSCLQD
.: .:.: ..:.::::.: . ::: . : .:...:...:. :. ::: : :::: ...
CCDS32 ILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIME
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 RFRFNEIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVIDFS
.:.. :::: .:::: :..::: ::::::::: .::. ::::.. : :.::...
CCDS32 QFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE
130 140 150 160 170
>>CCDS11249.1 CRYBA1 gene_id:1411|Hs108|chr17 (215 aa)
initn: 300 init1: 103 opt: 363 Z-score: 485.4 bits: 96.6 E(32554): 1e-20
Smith-Waterman score: 363; 33.3% identity (67.2% similar) in 183 aa overlap (3-170:32-213)
10 20 30
pF1KE6 MGKITLYEDRGFQGRHYECSSDHPNLQPY-LS
:::.:....:::...: .:. ::.. ..
CCDS11 ETQAEQQELETLPTTKMAQTNPTPGSLGPWKITIYDQENFQGKRMEFTSSCPNVSERSFD
10 20 30 40 50 60
40 50 60 70 80
pF1KE6 RCNSARVDSGCWMLYEQPNYSGLQYFLRRGDYADHQQWMGLSDSVRSCRLIPH----SGS
: .:.:: :. ::. .. : :..:.::.: . : : :.. . ::. :..
CCDS11 NVRSLKVESGAWIGYEHTSFCGQQFILERGEYPRWDAWSG-SNAYHIERLMSFRPICSAN
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE6 HR---IRLYEREDYRGQMIEFTEDCSCLQDRFRFN-EIHSLNVLEGSWVLYELSNYRGRQ
:. . ..:.:.. :.. :...: :: :: :. :... :.:: :. .::: :
CCDS11 HKESKMTIFEKENFIGRQWEISDDYPSLQAMGWFNNEVGSMKIQSGAWVCYQYPGYRGYQ
130 140 150 160 170 180
150 160 170
pF1KE6 YLL----MPGDYRRYQDWG--ATNARVGSLRRVIDFS
:.: :::.....:: : .... :.::.
CCDS11 YILECDHHGGDYKHWREWGSHAQTSQIQSIRRIQQ
190 200 210
>>CCDS13830.1 CRYBB3 gene_id:1417|Hs108|chr22 (211 aa)
initn: 280 init1: 149 opt: 360 Z-score: 481.6 bits: 95.9 E(32554): 1.7e-20
Smith-Waterman score: 360; 34.3% identity (66.9% similar) in 175 aa overlap (3-172:25-199)
10 20 30
pF1KE6 MGKITLYEDRGFQGRHYECSSDHPNL-QPYLSRCNSAR
:. ::: ..:::.. : :.. :.: . : . .: .
CCDS13 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 VDSGCWMLYEQPNYSGLQYFLRRGDYADHQQWMGL--SDSVRSCR-LIPHSGSHRIRLYE
:.:: :. .:. . : :. :..::: . : . :::. : : : : :...:.:
CCDS13 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFE
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 REDYRGQMIEFTED-CSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRR
. :. .:...: : . ... :. ...:.:: ::. .::::::.. :.::.
CCDS13 NPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRH
130 140 150 160 170 180
160 170
pF1KE6 YQDWGATNARVGSLRRVIDFS
...: :.. .. :.::. :
CCDS13 WNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
190 200 210
>>CCDS13840.1 CRYBB1 gene_id:1414|Hs108|chr22 (252 aa)
initn: 351 init1: 164 opt: 357 Z-score: 476.4 bits: 95.2 E(32554): 3.2e-20
Smith-Waterman score: 357; 35.4% identity (64.6% similar) in 178 aa overlap (3-172:60-234)
10 20 30
pF1KE6 MGKITLYEDRGFQGRHYECSSDHPNLQPY-LS
.....: ..::::. : :.. :: ..
CCDS13 GTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADRGFD
30 40 50 60 70 80
40 50 60 70 80
pF1KE6 RCNSARVDSGCWMLYEQPNYSGLQYFLRRGDYADHQQWMGLSDSVRSCRLI---P---HS
: : :..: :. .:: :. : ...:..:.: .: :.: :: ::. : .
CCDS13 RVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYP---RWNTWSSSYRSDRLMSFRPIKMDA
90 100 110 120 130 140
90 100 110 120 130 140
pF1KE6 GSHRIRLYEREDYRGQMIEFT-EDCSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGRQY
:.: :.: ...:. ::. .: : ... :..: :.:: :. .::: ::
CCDS13 QEHKISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQY
150 160 170 180 190 200
150 160 170
pF1KE6 LLMPGDYRRYQDWGATNARVGSLRRVIDFS
:: :::.:....::: . .. ::::. :
CCDS13 LLEPGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK
210 220 230 240 250
>>CCDS13831.1 CRYBB2 gene_id:1415|Hs108|chr22 (205 aa)
initn: 365 init1: 142 opt: 348 Z-score: 465.9 bits: 92.9 E(32554): 1.2e-19
Smith-Waterman score: 348; 34.9% identity (64.6% similar) in 175 aa overlap (3-172:18-192)
10 20 30 40
pF1KE6 MGKITLYEDRGFQGRHYECSSDHPNLQPY-LSRCNSARVDSGCWM
:: ..:...:::. .: .. :::. . . .:. :..: :.
CCDS13 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 LYEQPNYSGLQYFLRRGDYADHQQWMGL--SDSVRSCRLIP-HSGSHRIRLYEREDYRGQ
::: : .: :. ...:.: ..: . .::. : : : : :.: ::: .. :.
CCDS13 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE6 MIEFTED-CSCLQDRFRFNEIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGAT
.:. .: .. . ... :. : :.:: :. .::: :::: :::. .:.::
CCDS13 KMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAP
130 140 150 160 170 180
170
pF1KE6 NARVGSLRRVIDFS
. .: :.::. :
CCDS13 HPQVQSVRRIRDMQWHQRGAFHPSN
190 200
>>CCDS34506.1 AIM1 gene_id:202|Hs108|chr6 (1723 aa)
initn: 360 init1: 158 opt: 276 Z-score: 356.3 bits: 75.7 E(32554): 1.6e-13
Smith-Waterman score: 276; 33.5% identity (62.9% similar) in 170 aa overlap (3-168:1416-1581)
10 20 30
pF1KE6 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSR
.: :. . :::. ... .:
CCDS34 SFEDWGGKNCKISSVQPICLDSFTGPRRRNQIHLFSEPQFQGHSQSFEETTSQIDDSFST
1390 1400 1410 1420 1430 1440
40 50 60 70 80
pF1KE6 CNSARVDSGCWMLYEQPNYSGLQYFLRRGDYADHQQWMGLSD--SVRSCRLIPHSGSH-R
.: ::..: :..:. :..: :: :..: : . :: . .: :.: :.
CCDS34 -KSCRVSGGSWVVYDGENFTGNQYVLEEGHYP-CLSAMGCPPGATFKSLRFIDVEFSEPT
1450 1460 1470 1480 1490 1500
90 100 110 120 130 140
pF1KE6 IRLYEREDYRGQMIEFTEDCSCLQDRFRFN-EIHSLNVLEGSWVLYELSNYRGRQYLLMP
: :.::::..:. ::.. . :.. . :: .:.:..:. : :: :: ..:::::.:: :
CCDS34 IILFEREDFKGKKIELNAETVNLRS-LGFNTQIRSVQVIGGIWVTYEYGSYRGRQFLLSP
1510 1520 1530 1540 1550 1560
150 160 170
pF1KE6 GDYRRYQDWGATNARVGSLRRVIDFS
.. . .... ..::::
CCDS34 AEVPNWYEFSGCR-QIGSLRPFVQKRIYFRLRNKATGLFMSTNGNLEDLKLLRIQVMEDV
1570 1580 1590 1600 1610 1620
174 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 14:07:11 2016 done: Tue Nov 8 14:07:11 2016
Total Scan time: 1.160 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]