Result of FASTA (omim) for
pFN21AE6672
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6672, 307 aa
1>>>pF1KE6672 307 - 307 aa - 307 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5163+/-0.000398; mu= 13.7724+/- 0.025
mean_var=62.4808+/-12.585, 0's: 0 Z-trim(111.0): 23 B-trim: 0 in 0/53
Lambda= 0.162256
statistics sampled from 19506 (19511) to 19506 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.623), E-opt: 0.2 (0.229), width: 16
Scan time: 5.990
The best scores are: opt bits E(85289)
XP_016860706 (OMIM: 236800,605197) PREDICTED: kynu ( 307) 2062 491.6 8.6e-139
NP_001028170 (OMIM: 236800,605197) kynureninase is ( 307) 2062 491.6 8.6e-139
NP_003928 (OMIM: 236800,605197) kynureninase isofo ( 465) 2022 482.3 8.2e-136
NP_001186170 (OMIM: 236800,605197) kynureninase is ( 465) 2022 482.3 8.2e-136
XP_011510404 (OMIM: 236800,605197) PREDICTED: kynu ( 332) 1133 274.1 2.7e-73
>>XP_016860706 (OMIM: 236800,605197) PREDICTED: kynureni (307 aa)
initn: 2062 init1: 2062 opt: 2062 Z-score: 2612.8 bits: 491.6 E(85289): 8.6e-139
Smith-Waterman score: 2062; 100.0% identity (100.0% similar) in 307 aa overlap (1-307:1-307)
10 20 30 40 50 60
pF1KE6 MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
250 260 270 280 290 300
pF1KE6 ARSEFFN
:::::::
XP_016 ARSEFFN
>>NP_001028170 (OMIM: 236800,605197) kynureninase isofor (307 aa)
initn: 2062 init1: 2062 opt: 2062 Z-score: 2612.8 bits: 491.6 E(85289): 8.6e-139
Smith-Waterman score: 2062; 100.0% identity (100.0% similar) in 307 aa overlap (1-307:1-307)
10 20 30 40 50 60
pF1KE6 MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
250 260 270 280 290 300
pF1KE6 ARSEFFN
:::::::
NP_001 ARSEFFN
>>NP_003928 (OMIM: 236800,605197) kynureninase isoform a (465 aa)
initn: 2021 init1: 2021 opt: 2022 Z-score: 2559.3 bits: 482.3 E(85289): 8.2e-136
Smith-Waterman score: 2022; 98.7% identity (99.0% similar) in 306 aa overlap (1-306:1-306)
10 20 30 40 50 60
pF1KE6 MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
250 260 270 280 290 300
pF1KE6 ARSEFFN
: .:
NP_003 ALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKK
310 320 330 340 350 360
>>NP_001186170 (OMIM: 236800,605197) kynureninase isofor (465 aa)
initn: 2021 init1: 2021 opt: 2022 Z-score: 2559.3 bits: 482.3 E(85289): 8.2e-136
Smith-Waterman score: 2022; 98.7% identity (99.0% similar) in 306 aa overlap (1-306:1-306)
10 20 30 40 50 60
pF1KE6 MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
250 260 270 280 290 300
pF1KE6 ARSEFFN
: .:
NP_001 ALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKK
310 320 330 340 350 360
>>XP_011510404 (OMIM: 236800,605197) PREDICTED: kynureni (332 aa)
initn: 1132 init1: 1132 opt: 1133 Z-score: 1436.9 bits: 274.1 E(85289): 2.7e-73
Smith-Waterman score: 1133; 97.7% identity (98.3% similar) in 173 aa overlap (134-306:1-173)
110 120 130 140 150 160
pF1KE6 VGKRPWITGDESIVGLMKDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAK
::::::::::::::::::::::::::::::
XP_011 MNALTVNLHLLMLSFFKPTPKRYKILLEAK
10 20 30
170 180 190 200 210 220
pF1KE6 AFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGV
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE6 HFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAG
100 110 120 130 140 150
290 300
pF1KE6 GIAGAFIHEKHAHTIKPARSEFFN
:::::::::::::::::: .:
XP_011 GIAGAFIHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLH
160 170 180 190 200 210
307 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 15:18:14 2016 done: Tue Nov 8 15:18:15 2016
Total Scan time: 5.990 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]