Result of FASTA (omim) for
pFN21AE6648
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6648, 223 aa
1>>>pF1KE6648 223 - 223 aa - 223 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4864+/-0.000296; mu= 14.5922+/- 0.018
mean_var=118.0230+/-22.271, 0's: 0 Z-trim(121.2): 123 B-trim: 61 in 1/55
Lambda= 0.118057
statistics sampled from 37377 (37586) to 37377 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.793), E-opt: 0.2 (0.441), width: 16
Scan time: 5.330
The best scores are: opt bits E(85289)
NP_115934 (OMIM: 217095,605194,605376,613853) cryp ( 223) 1631 287.9 9.3e-78
NP_001257349 (OMIM: 217095,605194,605376,613853) c ( 191) 585 109.6 3.6e-24
XP_011509788 (OMIM: 217095,605194,605376,613853) P ( 142) 565 106.1 3.1e-23
NP_001257350 (OMIM: 217095,605194,605376,613853) c ( 148) 565 106.1 3.2e-23
NP_001167607 (OMIM: 187395) teratocarcinoma-derive ( 172) 319 64.3 1.5e-10
NP_003203 (OMIM: 187395) teratocarcinoma-derived g ( 188) 319 64.3 1.5e-10
NP_963845 (OMIM: 602319) protein kinase C-binding ( 763) 186 42.4 0.0025
>>NP_115934 (OMIM: 217095,605194,605376,613853) cryptic (223 aa)
initn: 1631 init1: 1631 opt: 1631 Z-score: 1517.0 bits: 287.9 E(85289): 9.3e-78
Smith-Waterman score: 1631; 100.0% identity (100.0% similar) in 223 aa overlap (1-223:1-223)
10 20 30 40 50 60
pF1KE6 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VTGSAEGWGPEEPLPYSRAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 VTGSAEGWGPEEPLPYSRAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 SECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLL
130 140 150 160 170 180
190 200 210 220
pF1KE6 LLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL
:::::::::::::::::::::::::::::::::::::::::::
NP_115 LLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL
190 200 210 220
>>NP_001257349 (OMIM: 217095,605194,605376,613853) crypt (191 aa)
initn: 623 init1: 565 opt: 585 Z-score: 554.9 bits: 109.6 E(85289): 3.6e-24
Smith-Waterman score: 585; 58.2% identity (68.1% similar) in 182 aa overlap (1-177:1-176)
10 20 30 40 50 60
pF1KE6 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE
10 20 30 40 50 60
70 80 90 100 110
pF1KE6 VTGSAEGWGPEEPLPYSRAFGEGASARPRCCRNG----GTCVLGSFCVCPAHFTGRYCEH
:::::::::::::::::::::: ..: : . : .: . .: : : . :
NP_001 VTGSAEGWGPEEPLPYSRAFGE-VNAAPWSTEPGPSAPATSAGASSGPCTASPSRRLTAV
70 80 90 100 110
120 130 140 150 160 170
pF1KE6 DQRRSECGALEHGAWTLR-ACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGA
.. : .: : : ::. : : : : . : :. . . :..::
NP_001 TRKTSWPPTLTGRAPGARPACYSC-C--PAHSCT--ASCARMRPRTLGPWSLPSSSGSGA
120 130 140 150 160 170
180 190 200 210 220
pF1KE6 PSLLLLLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL
:.
NP_001 PAEGRDLGIAFNFLCCK
180 190
>>XP_011509788 (OMIM: 217095,605194,605376,613853) PREDI (142 aa)
initn: 565 init1: 565 opt: 565 Z-score: 538.0 bits: 106.1 E(85289): 3.1e-23
Smith-Waterman score: 565; 100.0% identity (100.0% similar) in 82 aa overlap (1-82:1-82)
10 20 30 40 50 60
pF1KE6 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VTGSAEGWGPEEPLPYSRAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRR
::::::::::::::::::::::
XP_011 VTGSAEGWGPEEPLPYSRAFGEDLENCDLNVLKINIPSQDNSGLLLGFSQTPRPQEAPRR
70 80 90 100 110 120
>>NP_001257350 (OMIM: 217095,605194,605376,613853) crypt (148 aa)
initn: 565 init1: 565 opt: 565 Z-score: 537.8 bits: 106.1 E(85289): 3.2e-23
Smith-Waterman score: 876; 66.4% identity (66.4% similar) in 223 aa overlap (1-223:1-148)
10 20 30 40 50 60
pF1KE6 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTWRHHVRLLFTVSLALQIINLGNSYQREKHNGGREEVTKVATQKHRQSPLNWTSSHFGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VTGSAEGWGPEEPLPYSRAFGEGASARPRCCRNGGTCVLGSFCVCPAHFTGRYCEHDQRR
::::::::::::::::::::::
NP_001 VTGSAEGWGPEEPLPYSRAFGE--------------------------------------
70 80
130 140 150 160 170 180
pF1KE6 SECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHAHGPSAGGAPSLLL
:::::::::::::::::::::::
NP_001 -------------------------------------DPKDFLASHAHGPSAGGAPSLLL
90 100
190 200 210 220
pF1KE6 LLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL
:::::::::::::::::::::::::::::::::::::::::::
NP_001 LLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL
110 120 130 140
>>NP_001167607 (OMIM: 187395) teratocarcinoma-derived gr (172 aa)
initn: 336 init1: 316 opt: 319 Z-score: 310.6 bits: 64.3 E(85289): 1.5e-10
Smith-Waterman score: 319; 37.7% identity (58.5% similar) in 130 aa overlap (68-184:36-165)
40 50 60 70 80
pF1KE6 VTKVATQKHRQSPLNWTSSHFGEVTGSAEGWGPEEPL--PYS--RAFGEGASARPR----
: ::: : : :. : . .
NP_001 VFELGLVAGLGHQEFARPSRGYLAFRDDSIWPQEEPAIRPRSSQRVPPMGIQHSKELNRT
10 20 30 40 50 60
90 100 110 120 130 140
pF1KE6 CCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCL
:: :::::.:::::.:: : :: :::: :. .::.. : .: . : ::.: : :.:.
NP_001 CCLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLRCF
70 80 90 100 110 120
150 160 170 180 190 200
pF1KE6 PLQTPDRCD----PKDFLASHA-HGPSAGGAPSLLLLLPCALLHRLLRPDAPAHPRSLVP
: :: . ..::.. . : .. . ...:. :
NP_001 PQAFLPGCDGLVMDEHLVASRTPELPPSARTTTFMLVGICLSIQSYY
130 140 150 160 170
210 220
pF1KE6 SVLQRERRPCGRPGLGHRL
>>NP_003203 (OMIM: 187395) teratocarcinoma-derived growt (188 aa)
initn: 316 init1: 316 opt: 319 Z-score: 310.1 bits: 64.3 E(85289): 1.5e-10
Smith-Waterman score: 319; 37.7% identity (58.5% similar) in 130 aa overlap (68-184:52-181)
40 50 60 70 80
pF1KE6 VTKVATQKHRQSPLNWTSSHFGEVTGSAEGWGPEEPL--PYS--RAFGEGASARPR----
: ::: : : :. : . .
NP_003 VFELGLVAGLGHQEFARPSRGYLAFRDDSIWPQEEPAIRPRSSQRVPPMGIQHSKELNRT
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE6 CCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCL
:: :::::.:::::.:: : :: :::: :. .::.. : .: . : ::.: : :.:.
NP_003 CCLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLRCF
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE6 PLQTPDRCD----PKDFLASHA-HGPSAGGAPSLLLLLPCALLHRLLRPDAPAHPRSLVP
: :: . ..::.. . : .. . ...:. :
NP_003 PQAFLPGCDGLVMDEHLVASRTPELPPSARTTTFMLVGICLSIQSYY
150 160 170 180
210 220
pF1KE6 SVLQRERRPCGRPGLGHRL
>>NP_963845 (OMIM: 602319) protein kinase C-binding prot (763 aa)
initn: 200 init1: 139 opt: 186 Z-score: 180.6 bits: 42.4 E(85289): 0.0025
Smith-Waterman score: 186; 40.0% identity (57.5% similar) in 80 aa overlap (81-157:510-583)
60 70 80 90 100
pF1KE6 LNWTSSHFGEVTGSAEGWGPEEPLPYSRAFGEGASARPRC---CRNGGTCVLGSFCVCPA
:.:. : : :: ::::: . ::::.
NP_963 CGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPS
480 490 500 510 520 530
110 120 130 140 150 160
pF1KE6 HFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCLPLQTPDRCDPKDFLASHA
::: .::.: .::. : :. :: . :.. :: . :. :
NP_963 GFTGSHCEKDI--DECALRTHTCWNDSACI---NLAGGFDCLCPSGPS-CSGDCPHEGGL
540 550 560 570 580 590
170 180 190 200 210 220
pF1KE6 HGPSAGGAPSLLLLLPCALLHRLLRPDAPAHPRSLVPSVLQRERRPCGRPGLGHRL
NP_963 KHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSADLFCCPECDTRVTSQCLDQNGH
600 610 620 630 640 650
223 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 15:06:18 2016 done: Tue Nov 8 15:06:19 2016
Total Scan time: 5.330 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]