Result of FASTA (omim) for
pFN21AE5460
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5460, 334 aa
1>>>pF1KE5460 334 - 334 aa - 334 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9464+/-0.000444; mu= 18.0208+/- 0.027
mean_var=65.3756+/-13.237, 0's: 0 Z-trim(109.1): 44 B-trim: 536 in 1/55
Lambda= 0.158623
statistics sampled from 17219 (17249) to 17219 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.554), E-opt: 0.2 (0.202), width: 16
Scan time: 7.400
The best scores are: opt bits E(85289)
NP_005908 (OMIM: 154200) malate dehydrogenase, cyt ( 334) 2155 502.4 5.6e-142
NP_001303303 (OMIM: 154200) malate dehydrogenase, ( 353) 2155 502.4 5.9e-142
NP_001186040 (OMIM: 154200) malate dehydrogenase, ( 352) 2148 500.8 1.8e-141
NP_001186041 (OMIM: 154200) malate dehydrogenase, ( 245) 1594 373.9 2e-103
NP_002291 (OMIM: 150100,614128) L-lactate dehydrog ( 334) 220 59.5 1.1e-08
NP_001167568 (OMIM: 150100,614128) L-lactate dehyd ( 334) 220 59.5 1.1e-08
NP_001302466 (OMIM: 150100,614128) L-lactate dehyd ( 341) 220 59.6 1.1e-08
XP_006719137 (OMIM: 150100,614128) PREDICTED: L-la ( 353) 199 54.8 3.3e-07
NP_005557 (OMIM: 150000,612933) L-lactate dehydrog ( 332) 187 52.0 2.1e-06
NP_001158886 (OMIM: 150000,612933) L-lactate dehyd ( 361) 187 52.0 2.2e-06
NP_059144 (OMIM: 150150) L-lactate dehydrogenase C ( 332) 186 51.8 2.5e-06
NP_002292 (OMIM: 150150) L-lactate dehydrogenase C ( 332) 186 51.8 2.5e-06
NP_005909 (OMIM: 154100) malate dehydrogenase, mit ( 338) 182 50.9 4.7e-06
NP_001158887 (OMIM: 150000,612933) L-lactate dehyd ( 274) 179 50.1 6.4e-06
NP_001158888 (OMIM: 150000,612933) L-lactate dehyd ( 241) 160 45.7 0.00012
NP_001269332 (OMIM: 154100) malate dehydrogenase, ( 296) 140 41.2 0.0033
>>NP_005908 (OMIM: 154200) malate dehydrogenase, cytopla (334 aa)
initn: 2155 init1: 2155 opt: 2155 Z-score: 2669.9 bits: 502.4 E(85289): 5.6e-142
Smith-Waterman score: 2155; 100.0% identity (100.0% similar) in 334 aa overlap (1-334:1-334)
10 20 30 40 50 60
pF1KE5 MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 KKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAAVIKARKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAAVIKARKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 SSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKFV
250 260 270 280 290 300
310 320 330
pF1KE5 EGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
::::::::::::::::::::::::::::::::::
NP_005 EGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
310 320 330
>>NP_001303303 (OMIM: 154200) malate dehydrogenase, pero (353 aa)
initn: 2155 init1: 2155 opt: 2155 Z-score: 2669.5 bits: 502.4 E(85289): 5.9e-142
Smith-Waterman score: 2155; 100.0% identity (100.0% similar) in 334 aa overlap (1-334:1-334)
10 20 30 40 50 60
pF1KE5 MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 KKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 VIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAAVIKARKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAAVIKARKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 SSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKFV
250 260 270 280 290 300
310 320 330
pF1KE5 EGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
::::::::::::::::::::::::::::::::::
NP_001 EGLPINDFSREKMDLTAKELTEEKESAFEFLSSAXLDNDVTKCFKAEESKCRL
310 320 330 340 350
>>NP_001186040 (OMIM: 154200) malate dehydrogenase, cyto (352 aa)
initn: 2148 init1: 2148 opt: 2148 Z-score: 2660.9 bits: 500.8 E(85289): 1.8e-141
Smith-Waterman score: 2148; 100.0% identity (100.0% similar) in 333 aa overlap (2-334:20-352)
10 20 30 40
pF1KE5 MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLD
:::::::::::::::::::::::::::::::::::::::::
NP_001 MRRCSYFPKDVTVFDKDDKSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLD
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 ITPMMGVLDGVLMELQDCALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITPMMGVLDGVLMELQDCALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLL
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE5 KANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNR
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE5 AKAQIALKLGVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKAQIALKLGVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGE
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE5 FVTTVQQRGAAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVTTVQQRGAAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPD
250 260 270 280 290 300
290 300 310 320 330
pF1KE5 DLLYSFPVVIKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLLYSFPVVIKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
310 320 330 340 350
>>NP_001186041 (OMIM: 154200) malate dehydrogenase, cyto (245 aa)
initn: 1594 init1: 1594 opt: 1594 Z-score: 1977.9 bits: 373.9 E(85289): 2e-103
Smith-Waterman score: 1594; 100.0% identity (100.0% similar) in 245 aa overlap (90-334:1-245)
60 70 80 90 100 110
pF1KE5 CALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKY
::::::::::::::::::::::::::::::
NP_001 MPRREGMERKDLLKANVKIFKSQGAALDKY
10 20 30
120 130 140 150 160 170
pF1KE5 AKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVK
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE5 NVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAAVIKARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAAVIKARK
100 110 120 130 140 150
240 250 260 270 280 290
pF1KE5 LSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIKNKTWKF
160 170 180 190 200 210
300 310 320 330
pF1KE5 VEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
:::::::::::::::::::::::::::::::::::
NP_001 VEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
220 230 240
>>NP_002291 (OMIM: 150100,614128) L-lactate dehydrogenas (334 aa)
initn: 114 init1: 114 opt: 220 Z-score: 276.7 bits: 59.5 E(85289): 1.1e-08
Smith-Waterman score: 220; 24.1% identity (55.9% similar) in 324 aa overlap (6-320:23-324)
10 20 30 40
pF1KE5 MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDI
.. :.:. ::.... :: .::. :.:.:.
NP_002 MATLKEKLIAPVAEEEATVPNNKITVVGV-GQVGMACAISI-----LGKSLADELALVDV
10 20 30 40 50
50 60 70 80 90 100
pF1KE5 TPMMGVLDGVLMELQDCALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLK
. : : .:.:: .: : :..::. . . ........ ..:: : .:..
NP_002 --LEDKLKGEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQ
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE5 ANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENF---SCLTRLDH
::..:: . ::. . .:::.::.. .. : . ..::. .: ::
NP_002 RNVNVFKFIIPQIVKYSPDCI-IIVVSNPVDILTYVTWKLS-GLPKHRVIGSGC--NLDS
120 130 140 150 160
170 180 190 200 210
pF1KE5 NRAKAQIALKLGVTANDVKNVIIWGNHSSTQ---YPDVNHAKVKLQGKEVGVYEALKDDS
: . .: :::. .. .. :. :.:.... . :: : :.:: :.. . .::
NP_002 ARFRYLMAEKLGIHPSSCHGWIL-GEHGDSSVAVWSGVNVAGVSLQ--ELNPEMGTDNDS
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE5 WLKGEFVTTVQQRGAAVIKARKLSS---AMSAAKAICDHVRDIWFGTPEGEFVSMGVISD
: : . . ::: . .. ..:.: : . .... : . .:. :.
NP_002 ENWKEVHKMVVESAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVK-GM---
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE5 GNSYGVPDDLLYSFPVVIKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
::. .... :.: ... . : . ..: .. .: :
NP_002 ---YGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQLKKSADTLWDIQKDLKDL
290 300 310 320 330
>>NP_001167568 (OMIM: 150100,614128) L-lactate dehydroge (334 aa)
initn: 114 init1: 114 opt: 220 Z-score: 276.7 bits: 59.5 E(85289): 1.1e-08
Smith-Waterman score: 220; 24.1% identity (55.9% similar) in 324 aa overlap (6-320:23-324)
10 20 30 40
pF1KE5 MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDI
.. :.:. ::.... :: .::. :.:.:.
NP_001 MATLKEKLIAPVAEEEATVPNNKITVVGV-GQVGMACAISI-----LGKSLADELALVDV
10 20 30 40 50
50 60 70 80 90 100
pF1KE5 TPMMGVLDGVLMELQDCALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLK
. : : .:.:: .: : :..::. . . ........ ..:: : .:..
NP_001 --LEDKLKGEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQ
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE5 ANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENF---SCLTRLDH
::..:: . ::. . .:::.::.. .. : . ..::. .: ::
NP_001 RNVNVFKFIIPQIVKYSPDCI-IIVVSNPVDILTYVTWKLS-GLPKHRVIGSGC--NLDS
120 130 140 150 160
170 180 190 200 210
pF1KE5 NRAKAQIALKLGVTANDVKNVIIWGNHSSTQ---YPDVNHAKVKLQGKEVGVYEALKDDS
: . .: :::. .. .. :. :.:.... . :: : :.:: :.. . .::
NP_001 ARFRYLMAEKLGIHPSSCHGWIL-GEHGDSSVAVWSGVNVAGVSLQ--ELNPEMGTDNDS
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE5 WLKGEFVTTVQQRGAAVIKARKLSS---AMSAAKAICDHVRDIWFGTPEGEFVSMGVISD
: : . . ::: . .. ..:.: : . .... : . .:. :.
NP_001 ENWKEVHKMVVESAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVK-GM---
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE5 GNSYGVPDDLLYSFPVVIKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
::. .... :.: ... . : . ..: .. .: :
NP_001 ---YGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQLKKSADTLWDIQKDLKDL
290 300 310 320 330
>>NP_001302466 (OMIM: 150100,614128) L-lactate dehydroge (341 aa)
initn: 114 init1: 114 opt: 220 Z-score: 276.6 bits: 59.6 E(85289): 1.1e-08
Smith-Waterman score: 220; 24.1% identity (55.9% similar) in 324 aa overlap (6-320:23-324)
10 20 30 40
pF1KE5 MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDI
.. :.:. ::.... :: .::. :.:.:.
NP_001 MATLKEKLIAPVAEEEATVPNNKITVVGV-GQVGMACAISI-----LGKSLADELALVDV
10 20 30 40 50
50 60 70 80 90 100
pF1KE5 TPMMGVLDGVLMELQDCALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLK
. : : .:.:: .: : :..::. . . ........ ..:: : .:..
NP_001 --LEDKLKGEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQ
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE5 ANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENF---SCLTRLDH
::..:: . ::. . .:::.::.. .. : . ..::. .: ::
NP_001 RNVNVFKFIIPQIVKYSPDCI-IIVVSNPVDILTYVTWKLS-GLPKHRVIGSGC--NLDS
120 130 140 150 160
170 180 190 200 210
pF1KE5 NRAKAQIALKLGVTANDVKNVIIWGNHSSTQ---YPDVNHAKVKLQGKEVGVYEALKDDS
: . .: :::. .. .. :. :.:.... . :: : :.:: :.. . .::
NP_001 ARFRYLMAEKLGIHPSSCHGWIL-GEHGDSSVAVWSGVNVAGVSLQ--ELNPEMGTDNDS
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE5 WLKGEFVTTVQQRGAAVIKARKLSS---AMSAAKAICDHVRDIWFGTPEGEFVSMGVISD
: : . . ::: . .. ..:.: : . .... : . .:. :.
NP_001 ENWKEVHKMVVESAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVK-GM---
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE5 GNSYGVPDDLLYSFPVVIKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
::. .... :.: ... . : . ..: .. .: :
NP_001 ---YGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQLKKSADTLWDIQKDLKDLXLVS
290 300 310 320 330
NP_001 SRL
340
>>XP_006719137 (OMIM: 150100,614128) PREDICTED: L-lactat (353 aa)
initn: 114 init1: 114 opt: 199 Z-score: 250.4 bits: 54.8 E(85289): 3.3e-07
Smith-Waterman score: 199; 25.7% identity (57.5% similar) in 261 aa overlap (6-257:23-268)
10 20 30 40
pF1KE5 MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDI
.. :.:. ::.... :: .::. :.:.:.
XP_006 MATLKEKLIAPVAEEEATVPNNKITVVGV-GQVGMACAISI-----LGKSLADELALVDV
10 20 30 40 50
50 60 70 80 90 100
pF1KE5 TPMMGVLDGVLMELQDCALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLK
. : : .:.:: .: : :..::. . . ........ ..:: : .:..
XP_006 --LEDKLKGEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQ
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE5 ANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENF---SCLTRLDH
::..:: . ::. . .:::.::.. .. : . ..::. .: ::
XP_006 RNVNVFKFIIPQIVKYSPDCI-IIVVSNPVDILTYVTWKLS-GLPKHRVIGSGC--NLDS
120 130 140 150 160
170 180 190 200 210
pF1KE5 NRAKAQIALKLGVTANDVKNVIIWGNHSSTQ---YPDVNHAKVKLQGKEVGVYEALKDDS
: . .: :::. .. .. :. :.:.... . :: : :.:: :.. . .::
XP_006 ARFRYLMAEKLGIHPSSCHGWIL-GEHGDSSVAVWSGVNVAGVSLQ--ELNPEMGTDNDS
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE5 WLKGEFVTTVQQRGAAVIKARKLSS---AMSAAKAICDHVRDIWFGTPEGEFVSMGVISD
: : . . ::: . .. ..:.: : . ....
XP_006 ENWKEVHKMVVESAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKVRQTTT
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE5 GNSYGVPDDLLYSFPVVIKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
XP_006 KCNMISRIVFYKKIHLKRLRPDKIIVQGYFCLSKFYVNYSHFPTEVLDSKGRKLRESKTF
290 300 310 320 330 340
>>NP_005557 (OMIM: 150000,612933) L-lactate dehydrogenas (332 aa)
initn: 156 init1: 63 opt: 187 Z-score: 235.9 bits: 52.0 E(85289): 2.1e-06
Smith-Waterman score: 191; 24.3% identity (54.9% similar) in 304 aa overlap (28-327:38-320)
10 20 30 40 50
pF1KE5 MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMEL
:.. :: :.:.:. . : : .:.:
NP_005 LIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDV--IEDKLKGEMMDL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 QDCALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALD
: .: : :.. :. . . ..:.... ..:: : .:.. ::.::: .
NP_005 QHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 KYAKKSVKVIVVGNPANTNCLTASKSAPSIPKEN-FSCLTRLDHNRAKAQIALKLGVTAN
::. . :...:.::.. .: : ..::. .. :: : . .. .:::
NP_005 KYSP-NCKLLIVSNPVDILTYVAWK-ISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE5 DVKNVIIWGNHSSTQYP---DVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAA
. .. .. :.:.... : .: : :.:. . . ..: : : . .
NP_005 SCHGWVL-GEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQW--KEVHKQVVESAYE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE5 VIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIK
::: . .: . . .. : ...: . . . :: . . ::. ::.. : : ..
NP_005 VIKLKGYTS-WAIGLSVADLAESIMKNLRRVHPVSTMI---KGLYGIKDDVFLSVPCILG
250 260 270 280 290
300 310 320 330
pF1KE5 NKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
.. :.:. :. ::..: .. :.::
NP_005 QNG--------ISDLV--KVTLTSEEEARLKKSADTLWGIQKELQF
300 310 320 330
>>NP_001158886 (OMIM: 150000,612933) L-lactate dehydroge (361 aa)
initn: 156 init1: 63 opt: 187 Z-score: 235.4 bits: 52.0 E(85289): 2.2e-06
Smith-Waterman score: 191; 24.3% identity (54.9% similar) in 304 aa overlap (28-327:67-349)
10 20 30 40 50
pF1KE5 MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMEL
:.. :: :.:.:. . : : .:.:
NP_001 LIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDV--IEDKLKGEMMDL
40 50 60 70 80 90
60 70 80 90 100 110
pF1KE5 QDCALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALD
: .: : :.. :. . . ..:.... ..:: : .:.. ::.::: .
NP_001 QHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVV
100 110 120 130 140 150
120 130 140 150 160 170
pF1KE5 KYAKKSVKVIVVGNPANTNCLTASKSAPSIPKEN-FSCLTRLDHNRAKAQIALKLGVTAN
::. . :...:.::.. .: : ..::. .. :: : . .. .:::
NP_001 KYSP-NCKLLIVSNPVDILTYVAWK-ISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPL
160 170 180 190 200 210
180 190 200 210 220 230
pF1KE5 DVKNVIIWGNHSSTQYP---DVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAA
. .. .. :.:.... : .: : :.:. . . ..: : : . .
NP_001 SCHGWVL-GEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQW--KEVHKQVVESAYE
220 230 240 250 260
240 250 260 270 280 290
pF1KE5 VIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVIK
::: . .: . . .. : ...: . . . :: . . ::. ::.. : : ..
NP_001 VIKLKGYTS-WAIGLSVADLAESIMKNLRRVHPVSTMI---KGLYGIKDDVFLSVPCILG
270 280 290 300 310 320
300 310 320 330
pF1KE5 NKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA
.. :.:. :. ::..: .. :.::
NP_001 QNG--------ISDLV--KVTLTSEEEARLKKSADTLWGIQKELQF
330 340 350 360
334 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 00:59:30 2016 done: Tue Nov 8 00:59:31 2016
Total Scan time: 7.400 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]