Result of FASTA (omim) for
pFN21AE5021
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5021, 430 aa
1>>>pF1KE5021 430 - 430 aa - 430 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6328+/-0.000308; mu= 22.1110+/- 0.019
mean_var=75.9278+/-15.702, 0's: 0 Z-trim(117.8): 61 B-trim: 1124 in 1/50
Lambda= 0.147188
statistics sampled from 30057 (30146) to 30057 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.702), E-opt: 0.2 (0.353), width: 16
Scan time: 8.590
The best scores are: opt bits E(85289)
NP_071338 (OMIM: 607366) potassium channel subfami ( 430) 2893 623.5 3.2e-178
NP_071337 (OMIM: 607367) potassium channel subfami ( 408) 1732 376.9 5.1e-104
XP_011507826 (OMIM: 603219) PREDICTED: potassium c ( 370) 254 63.0 1.4e-09
XP_011507824 (OMIM: 603219) PREDICTED: potassium c ( 370) 254 63.0 1.4e-09
XP_011507825 (OMIM: 603219) PREDICTED: potassium c ( 370) 254 63.0 1.4e-09
NP_055032 (OMIM: 603219) potassium channel subfami ( 411) 254 63.1 1.5e-09
XP_016856738 (OMIM: 603219) PREDICTED: potassium c ( 412) 254 63.1 1.5e-09
XP_016856737 (OMIM: 603219) PREDICTED: potassium c ( 422) 254 63.1 1.6e-09
NP_001017424 (OMIM: 603219) potassium channel subf ( 422) 254 63.1 1.6e-09
NP_001017425 (OMIM: 603219) potassium channel subf ( 426) 254 63.1 1.6e-09
NP_002236 (OMIM: 601745) potassium channel subfami ( 336) 248 61.7 3.2e-09
NP_001128579 (OMIM: 607369) potassium channel subf ( 262) 245 61.0 4.3e-09
XP_016866835 (OMIM: 607369) PREDICTED: potassium c ( 262) 245 61.0 4.3e-09
NP_001128578 (OMIM: 607369) potassium channel subf ( 294) 245 61.0 4.6e-09
NP_115491 (OMIM: 607369) potassium channel subfami ( 309) 245 61.0 4.8e-09
NP_001128577 (OMIM: 607369) potassium channel subf ( 322) 245 61.1 4.9e-09
NP_001304019 (OMIM: 605720) potassium channel subf ( 393) 240 60.1 1.2e-08
NP_201567 (OMIM: 605720) potassium channel subfami ( 393) 240 60.1 1.2e-08
NP_066984 (OMIM: 605873) potassium channel subfami ( 538) 241 60.4 1.3e-08
NP_612190 (OMIM: 605873) potassium channel subfami ( 543) 241 60.5 1.3e-08
NP_612191 (OMIM: 605873) potassium channel subfami ( 543) 241 60.5 1.3e-08
NP_002237 (OMIM: 603220,615344) potassium channel ( 394) 236 59.2 2.1e-08
NP_001269463 (OMIM: 605874,612292) potassium chann ( 374) 212 54.1 7e-07
XP_011515404 (OMIM: 605874,612292) PREDICTED: pota ( 374) 212 54.1 7e-07
NP_004814 (OMIM: 603939) potassium channel subfami ( 313) 211 53.8 7.2e-07
XP_011515403 (OMIM: 605874,612292) PREDICTED: pota ( 401) 212 54.2 7.3e-07
NP_071753 (OMIM: 607368) potassium channel subfami ( 330) 210 53.6 8.6e-07
NP_258416 (OMIM: 603940) potassium channel subfami ( 252) 205 52.5 1.5e-06
NP_203134 (OMIM: 603940) potassium channel subfami ( 252) 205 52.5 1.5e-06
NP_005705 (OMIM: 603940) potassium channel subfami ( 257) 205 52.5 1.5e-06
NP_203133 (OMIM: 603940) potassium channel subfami ( 307) 205 52.5 1.7e-06
XP_016869020 (OMIM: 605874,612292) PREDICTED: pota ( 264) 195 50.4 6.7e-06
XP_016869019 (OMIM: 605874,612292) PREDICTED: pota ( 264) 195 50.4 6.7e-06
XP_011515405 (OMIM: 605874,612292) PREDICTED: pota ( 291) 195 50.4 7.2e-06
XP_005264350 (OMIM: 603220,615344) PREDICTED: pota ( 284) 193 50.0 9.5e-06
XP_011513237 (OMIM: 607369) PREDICTED: potassium c ( 197) 185 48.1 2.4e-05
XP_011525828 (OMIM: 603939) PREDICTED: potassium c ( 179) 177 46.4 7.3e-05
NP_113648 (OMIM: 607370) potassium channel subfami ( 332) 179 47.1 8.3e-05
XP_011542486 (OMIM: 601745) PREDICTED: potassium c ( 268) 171 45.3 0.00023
XP_011535142 (OMIM: 605873) PREDICTED: potassium c ( 410) 169 45.0 0.00042
XP_006715298 (OMIM: 603493) PREDICTED: potassium c ( 317) 161 43.2 0.0011
XP_005249513 (OMIM: 603493) PREDICTED: potassium c ( 496) 163 43.8 0.0011
NP_003731 (OMIM: 603493) potassium channel subfami ( 499) 163 43.8 0.0012
XP_016883492 (OMIM: 607368) PREDICTED: potassium c ( 218) 147 40.1 0.0069
>>NP_071338 (OMIM: 607366) potassium channel subfamily K (430 aa)
initn: 2893 init1: 2893 opt: 2893 Z-score: 3320.6 bits: 623.5 E(85289): 3.2e-178
Smith-Waterman score: 2893; 100.0% identity (100.0% similar) in 430 aa overlap (1-430:1-430)
10 20 30 40 50 60
pF1KE5 MSSRSPRPPPRRSRRRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MSSRSPRPPPRRSRRRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSAL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 ESPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALAAGVRADALRPRWDFPGAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 ESPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALAAGVRADALRPRWDFPGAF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 YFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 YFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 ERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 ERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 WDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 WDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 LIKQVLNWMLRKLSCRCCARCCPAPGAPLARRNAITPGSRLRRRLAALGADPAARDSDAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LIKQVLNWMLRKLSCRCCARCCPAPGAPLARRNAITPGSRLRRRLAALGADPAARDSDAE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 GRRLSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GRRLSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMN
370 380 390 400 410 420
430
pF1KE5 NRLAETSASR
::::::::::
NP_071 NRLAETSASR
430
>>NP_071337 (OMIM: 607367) potassium channel subfamily K (408 aa)
initn: 1794 init1: 1392 opt: 1732 Z-score: 1988.5 bits: 376.9 E(85289): 5.1e-104
Smith-Waterman score: 1732; 65.5% identity (84.5% similar) in 400 aa overlap (31-430:12-408)
10 20 30 40 50 60
pF1KE5 MSSRSPRPPPRRSRRRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSAL
:::::..::.:::::: :::..::.:::::
NP_071 MAGRGFSWGPGHLNEDNARFLLLAALIVLYLLGGAAVFSAL
10 20 30 40
70 80 90 100 110 120
pF1KE5 ESPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALAAGVRADALRPRWDFPGAF
: : .:. :: : ::: .:.... :::.:::::: : ::.:.: .:::::: :::
NP_071 ELAHERQAKQRWEERLANFSRGHNLSRDELRGFLRHYEEATRAGIRVDNVRPRWDFTGAF
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 YFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACR
::::::::::::::::::::::: ::: ::: ::..:::::::::::.:...:.::..:.
NP_071 YFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMKSCH
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE5 ERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEG
.::::: : :: . .. :.:::::::::::.:.::: ..:.::::::::: .::
NP_071 QRQLRRRGALPQESLKDAGQCEVDSLAGWKPSVYYVMLILCTASILISCCASAMYTPIEG
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE5 WDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISI
:.: ::::::::.:::::::::::::.: :..:::::..::.:::.::::::::::::::
NP_071 WSYFDSLYFCFVAFSTIGFGDLVSSQNAHYESQGLYRFANFVFILMGVCCIYSLFNVISI
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE5 LIKQVLNWMLRKLSCRCCARCCPAPGAPLARRNAITPGSRLRRRLAALGADPAARDSDAE
:::: :::.:::.. :: .: : .:::.. ::: : .. .: .: .::..
NP_071 LIKQSLNWILRKMDSGCCPQC--QRGLLRSRRNVVMPGSVRNRCNISIETDGVA-ESDTD
290 300 310 320 330
370 380 390 400 410 420
pF1KE5 GRRLSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMN
:::::::.:::.:: :.::.:::.::::::: ::: :... . .:.: :::::::..:::
NP_071 GRRLSGEMISMKDLLAANKASLAILQKQLSEMANGCPHQTSTLARDNEFSGGVGAFAIMN
340 350 360 370 380 390
430
pF1KE5 NRLAETSASR
:::::::..:
NP_071 NRLAETSGDR
400
>>XP_011507826 (OMIM: 603219) PREDICTED: potassium chann (370 aa)
initn: 380 init1: 163 opt: 254 Z-score: 292.8 bits: 63.0 E(85289): 1.4e-09
Smith-Waterman score: 380; 28.4% identity (56.1% similar) in 335 aa overlap (45-368:12-313)
20 30 40 50 60 70
pF1KE5 RRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGA
.. :::. :::::.:::.: : :.
XP_011 MKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVI
10 20 30 40
80 90 100 110 120
pF1KE5 TLRNFSAAHG-VAEPELRAFLRHYEAALAAGV----RADALRPRWDFPGAFYFVGTVVST
..: . :. : :: .... ::. ::. .. .::. ..:.:.:::..:
XP_011 QKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 IGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGL
:::: .: : ::: : : :.:.: : :..:.. . ..
XP_011 IGFGNISPRTEGGKIFCIIYALLG---------------IPLFGFLLAGVGDQ-------
110 120 130
190 200 210 220 230 240
pF1KE5 LPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCC-----ASAMYTSVEGWDYV
: . : .: : : :.. :. : .. .: .. .:..: . .. .:::. .
XP_011 LGTIFGKGIAKVE-DTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSAL
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE5 DSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQ
:..:: .:..:::::: :.. . . .:. ...::.:. . .....:.
XP_011 DAIYFVVITLTTIGFGDYVAGG-SDIEYLDFYKPVVWFWILVGLAYFAAVLSMIG-----
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE5 VLNWMLRKLSCRCCARCCP-APGAPLARRNAITPGSRLRRRLAALGADPAARDSDAEGRR
.: :: .: . . : :. . .. ::::.. : : .. . :.
XP_011 --DW-LRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIK-RK
260 270 280 290 300
370 380 390 400 410 420
pF1KE5 LSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMNNRL
::.::
XP_011 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN
310 320 330 340 350 360
>>XP_011507824 (OMIM: 603219) PREDICTED: potassium chann (370 aa)
initn: 380 init1: 163 opt: 254 Z-score: 292.8 bits: 63.0 E(85289): 1.4e-09
Smith-Waterman score: 380; 28.4% identity (56.1% similar) in 335 aa overlap (45-368:12-313)
20 30 40 50 60 70
pF1KE5 RRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGA
.. :::. :::::.:::.: : :.
XP_011 MKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVI
10 20 30 40
80 90 100 110 120
pF1KE5 TLRNFSAAHG-VAEPELRAFLRHYEAALAAGV----RADALRPRWDFPGAFYFVGTVVST
..: . :. : :: .... ::. ::. .. .::. ..:.:.:::..:
XP_011 QKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 IGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGL
:::: .: : ::: : : :.:.: : :..:.. . ..
XP_011 IGFGNISPRTEGGKIFCIIYALLG---------------IPLFGFLLAGVGDQ-------
110 120 130
190 200 210 220 230 240
pF1KE5 LPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCC-----ASAMYTSVEGWDYV
: . : .: : : :.. :. : .. .: .. .:..: . .. .:::. .
XP_011 LGTIFGKGIAKVE-DTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSAL
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE5 DSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQ
:..:: .:..:::::: :.. . . .:. ...::.:. . .....:.
XP_011 DAIYFVVITLTTIGFGDYVAGG-SDIEYLDFYKPVVWFWILVGLAYFAAVLSMIG-----
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE5 VLNWMLRKLSCRCCARCCP-APGAPLARRNAITPGSRLRRRLAALGADPAARDSDAEGRR
.: :: .: . . : :. . .. ::::.. : : .. . :.
XP_011 --DW-LRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIK-RK
260 270 280 290 300
370 380 390 400 410 420
pF1KE5 LSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMNNRL
::.::
XP_011 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN
310 320 330 340 350 360
>>XP_011507825 (OMIM: 603219) PREDICTED: potassium chann (370 aa)
initn: 380 init1: 163 opt: 254 Z-score: 292.8 bits: 63.0 E(85289): 1.4e-09
Smith-Waterman score: 380; 28.4% identity (56.1% similar) in 335 aa overlap (45-368:12-313)
20 30 40 50 60 70
pF1KE5 RRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGA
.. :::. :::::.:::.: : :.
XP_011 MKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVI
10 20 30 40
80 90 100 110 120
pF1KE5 TLRNFSAAHG-VAEPELRAFLRHYEAALAAGV----RADALRPRWDFPGAFYFVGTVVST
..: . :. : :: .... ::. ::. .. .::. ..:.:.:::..:
XP_011 QKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE5 IGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGL
:::: .: : ::: : : :.:.: : :..:.. . ..
XP_011 IGFGNISPRTEGGKIFCIIYALLG---------------IPLFGFLLAGVGDQ-------
110 120 130
190 200 210 220 230 240
pF1KE5 LPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCC-----ASAMYTSVEGWDYV
: . : .: : : :.. :. : .. .: .. .:..: . .. .:::. .
XP_011 LGTIFGKGIAKVE-DTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSAL
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE5 DSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQ
:..:: .:..:::::: :.. . . .:. ...::.:. . .....:.
XP_011 DAIYFVVITLTTIGFGDYVAGG-SDIEYLDFYKPVVWFWILVGLAYFAAVLSMIG-----
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE5 VLNWMLRKLSCRCCARCCP-APGAPLARRNAITPGSRLRRRLAALGADPAARDSDAEGRR
.: :: .: . . : :. . .. ::::.. : : .. . :.
XP_011 --DW-LRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIK-RK
260 270 280 290 300
370 380 390 400 410 420
pF1KE5 LSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMNNRL
::.::
XP_011 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN
310 320 330 340 350 360
>>NP_055032 (OMIM: 603219) potassium channel subfamily K (411 aa)
initn: 380 init1: 163 opt: 254 Z-score: 292.2 bits: 63.1 E(85289): 1.5e-09
Smith-Waterman score: 380; 28.4% identity (56.1% similar) in 335 aa overlap (45-368:53-354)
20 30 40 50 60 70
pF1KE5 RRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGA
.. :::. :::::.:::.: : :.
NP_055 STKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVI
30 40 50 60 70 80
80 90 100 110 120
pF1KE5 TLRNFSAAHG-VAEPELRAFLRHYEAALAAGV----RADALRPRWDFPGAFYFVGTVVST
..: . :. : :: .... ::. ::. .. .::. ..:.:.:::..:
NP_055 QKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITT
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE5 IGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGL
:::: .: : ::: : : :.:.: : :..:.. . ..
NP_055 IGFGNISPRTEGGKIFCIIYALLG---------------IPLFGFLLAGVGDQ-------
150 160 170 180
190 200 210 220 230 240
pF1KE5 LPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCC-----ASAMYTSVEGWDYV
: . : .: : : :.. :. : .. .: .. .:..: . .. .:::. .
NP_055 LGTIFGKGIAKVE-DTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSAL
190 200 210 220 230
250 260 270 280 290 300
pF1KE5 DSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQ
:..:: .:..:::::: :.. . . .:. ...::.:. . .....:.
NP_055 DAIYFVVITLTTIGFGDYVAGG-SDIEYLDFYKPVVWFWILVGLAYFAAVLSMIG-----
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE5 VLNWMLRKLSCRCCARCCP-APGAPLARRNAITPGSRLRRRLAALGADPAARDSDAEGRR
.: :: .: . . : :. . .. ::::.. : : .. . :.
NP_055 --DW-LRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIK-RK
300 310 320 330 340
370 380 390 400 410 420
pF1KE5 LSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMNNRL
::.::
NP_055 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN
350 360 370 380 390 400
>>XP_016856738 (OMIM: 603219) PREDICTED: potassium chann (412 aa)
initn: 380 init1: 163 opt: 254 Z-score: 292.2 bits: 63.1 E(85289): 1.5e-09
Smith-Waterman score: 380; 28.4% identity (56.1% similar) in 335 aa overlap (45-368:54-355)
20 30 40 50 60 70
pF1KE5 RRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGA
.. :::. :::::.:::.: : :.
XP_016 STKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVI
30 40 50 60 70 80
80 90 100 110 120
pF1KE5 TLRNFSAAHG-VAEPELRAFLRHYEAALAAGV----RADALRPRWDFPGAFYFVGTVVST
..: . :. : :: .... ::. ::. .. .::. ..:.:.:::..:
XP_016 QKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITT
90 100 110 120 130 140
130 140 150 160 170 180
pF1KE5 IGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGL
:::: .: : ::: : : :.:.: : :..:.. . ..
XP_016 IGFGNISPRTEGGKIFCIIYALLG---------------IPLFGFLLAGVGDQ-------
150 160 170 180
190 200 210 220 230 240
pF1KE5 LPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCC-----ASAMYTSVEGWDYV
: . : .: : : :.. :. : .. .: .. .:..: . .. .:::. .
XP_016 LGTIFGKGIAKVE-DTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 DSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQ
:..:: .:..:::::: :.. . . .:. ...::.:. . .....:.
XP_016 DAIYFVVITLTTIGFGDYVAGG-SDIEYLDFYKPVVWFWILVGLAYFAAVLSMIG-----
250 260 270 280 290
310 320 330 340 350 360
pF1KE5 VLNWMLRKLSCRCCARCCP-APGAPLARRNAITPGSRLRRRLAALGADPAARDSDAEGRR
.: :: .: . . : :. . .. ::::.. : : .. . :.
XP_016 --DW-LRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIK-RK
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE5 LSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMNNRL
::.::
XP_016 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN
360 370 380 390 400 410
>>XP_016856737 (OMIM: 603219) PREDICTED: potassium chann (422 aa)
initn: 380 init1: 163 opt: 254 Z-score: 292.1 bits: 63.1 E(85289): 1.6e-09
Smith-Waterman score: 380; 28.4% identity (56.1% similar) in 335 aa overlap (45-368:64-365)
20 30 40 50 60 70
pF1KE5 RRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGA
.. :::. :::::.:::.: : :.
XP_016 STKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVI
40 50 60 70 80 90
80 90 100 110 120
pF1KE5 TLRNFSAAHG-VAEPELRAFLRHYEAALAAGV----RADALRPRWDFPGAFYFVGTVVST
..: . :. : :: .... ::. ::. .. .::. ..:.:.:::..:
XP_016 QKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITT
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE5 IGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGL
:::: .: : ::: : : :.:.: : :..:.. . ..
XP_016 IGFGNISPRTEGGKIFCIIYALLG---------------IPLFGFLLAGVGDQ-------
160 170 180 190
190 200 210 220 230 240
pF1KE5 LPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCC-----ASAMYTSVEGWDYV
: . : .: : : :.. :. : .. .: .. .:..: . .. .:::. .
XP_016 LGTIFGKGIAKVE-DTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSAL
200 210 220 230 240 250
250 260 270 280 290 300
pF1KE5 DSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQ
:..:: .:..:::::: :.. . . .:. ...::.:. . .....:.
XP_016 DAIYFVVITLTTIGFGDYVAGG-SDIEYLDFYKPVVWFWILVGLAYFAAVLSMIG-----
260 270 280 290 300
310 320 330 340 350 360
pF1KE5 VLNWMLRKLSCRCCARCCP-APGAPLARRNAITPGSRLRRRLAALGADPAARDSDAEGRR
.: :: .: . . : :. . .. ::::.. : : .. . :.
XP_016 --DW-LRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIK-RK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 LSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMNNRL
::.::
XP_016 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN
370 380 390 400 410 420
>>NP_001017424 (OMIM: 603219) potassium channel subfamil (422 aa)
initn: 380 init1: 163 opt: 254 Z-score: 292.1 bits: 63.1 E(85289): 1.6e-09
Smith-Waterman score: 380; 28.4% identity (56.1% similar) in 335 aa overlap (45-368:64-365)
20 30 40 50 60 70
pF1KE5 RRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGA
.. :::. :::::.:::.: : :.
NP_001 STKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVI
40 50 60 70 80 90
80 90 100 110 120
pF1KE5 TLRNFSAAHG-VAEPELRAFLRHYEAALAAGV----RADALRPRWDFPGAFYFVGTVVST
..: . :. : :: .... ::. ::. .. .::. ..:.:.:::..:
NP_001 QKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITT
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE5 IGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGL
:::: .: : ::: : : :.:.: : :..:.. . ..
NP_001 IGFGNISPRTEGGKIFCIIYALLG---------------IPLFGFLLAGVGDQ-------
160 170 180 190
190 200 210 220 230 240
pF1KE5 LPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCC-----ASAMYTSVEGWDYV
: . : .: : : :.. :. : .. .: .. .:..: . .. .:::. .
NP_001 LGTIFGKGIAKVE-DTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSAL
200 210 220 230 240 250
250 260 270 280 290 300
pF1KE5 DSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQ
:..:: .:..:::::: :.. . . .:. ...::.:. . .....:.
NP_001 DAIYFVVITLTTIGFGDYVAGG-SDIEYLDFYKPVVWFWILVGLAYFAAVLSMIG-----
260 270 280 290 300
310 320 330 340 350 360
pF1KE5 VLNWMLRKLSCRCCARCCP-APGAPLARRNAITPGSRLRRRLAALGADPAARDSDAEGRR
.: :: .: . . : :. . .. ::::.. : : .. . :.
NP_001 --DW-LRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIK-RK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 LSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMNNRL
::.::
NP_001 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN
370 380 390 400 410 420
>>NP_001017425 (OMIM: 603219) potassium channel subfamil (426 aa)
initn: 380 init1: 163 opt: 254 Z-score: 292.0 bits: 63.1 E(85289): 1.6e-09
Smith-Waterman score: 380; 28.4% identity (56.1% similar) in 335 aa overlap (45-368:68-369)
20 30 40 50 60 70
pF1KE5 RRLPRPSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGA
.. :::. :::::.:::.: : :.
NP_001 STKPTVLASRVESDTTINVMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVI
40 50 60 70 80 90
80 90 100 110 120
pF1KE5 TLRNFSAAHG-VAEPELRAFLRHYEAALAAGV----RADALRPRWDFPGAFYFVGTVVST
..: . :. : :: .... ::. ::. .. .::. ..:.:.:::..:
NP_001 QKQTFISQHSCVNSTELDELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITT
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE5 IGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGL
:::: .: : ::: : : :.:.: : :..:.. . ..
NP_001 IGFGNISPRTEGGKIFCIIYALLG---------------IPLFGFLLAGVGDQ-------
160 170 180 190
190 200 210 220 230 240
pF1KE5 LPATFRRGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCC-----ASAMYTSVEGWDYV
: . : .: : : :.. :. : .. .: .. .:..: . .. .:::. .
NP_001 LGTIFGKGIAKVE-DTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIFKHIEGWSAL
200 210 220 230 240 250
250 260 270 280 290 300
pF1KE5 DSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQ
:..:: .:..:::::: :.. . . .:. ...::.:. . .....:.
NP_001 DAIYFVVITLTTIGFGDYVAGG-SDIEYLDFYKPVVWFWILVGLAYFAAVLSMIG-----
260 270 280 290 300
310 320 330 340 350 360
pF1KE5 VLNWMLRKLSCRCCARCCP-APGAPLARRNAITPGSRLRRRLAALGADPAARDSDAEGRR
.: :: .: . . : :. . .. ::::.. : : .. . :.
NP_001 --DW-LRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSIK-RK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 LSGELISMRDLTASNKVSLALLQKQLSETANGYPRSVCVNTRQNGFSGGVGALGIMNNRL
::.::
NP_001 LSAELAGNHNQELTPCRRTLSVNHLTSERDVLPPLLKTESIYLNGLTPHCAGEEIAVIEN
370 380 390 400 410 420
430 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:14:30 2016 done: Tue Nov 8 04:14:32 2016
Total Scan time: 8.590 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]