Result of FASTA (omim) for
pFN21AE1638
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1638, 152 aa
1>>>pF1KE1638 152 - 152 aa - 152 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8144+/-0.00034; mu= 13.8299+/- 0.021
mean_var=55.2959+/-11.278, 0's: 0 Z-trim(114.1): 18 B-trim: 50 in 1/52
Lambda= 0.172476
statistics sampled from 23785 (23802) to 23785 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.279), width: 16
Scan time: 4.500
The best scores are: opt bits E(85289)
XP_005245231 (OMIM: 604564) PREDICTED: microsomal ( 152) 1030 264.0 6.6e-71
NP_004519 (OMIM: 604564) microsomal glutathione S- ( 152) 1030 264.0 6.6e-71
NP_002404 (OMIM: 601733) microsomal glutathione S- ( 147) 209 59.7 2e-09
XP_016863702 (OMIM: 601733) PREDICTED: microsomal ( 147) 209 59.7 2e-09
XP_016863701 (OMIM: 601733) PREDICTED: microsomal ( 147) 209 59.7 2e-09
XP_016863700 (OMIM: 601733) PREDICTED: microsomal ( 147) 209 59.7 2e-09
NP_001191295 (OMIM: 601733) microsomal glutathione ( 147) 209 59.7 2e-09
NP_665874 (OMIM: 246530,614037) leukotriene C4 syn ( 150) 135 41.3 0.00072
>>XP_005245231 (OMIM: 604564) PREDICTED: microsomal glut (152 aa)
initn: 1030 init1: 1030 opt: 1030 Z-score: 1394.0 bits: 264.0 E(85289): 6.6e-71
Smith-Waterman score: 1030; 100.0% identity (100.0% similar) in 152 aa overlap (1-152:1-152)
10 20 30 40 50 60
pF1KE1 MAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCIQRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCIQRA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 HQNTLEVYPPFLFFLAVGGVYHPRIASGLGLAWIVGRVLYAYGYYTGEPSKRSRGALGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HQNTLEVYPPFLFFLAVGGVYHPRIASGLGLAWIVGRVLYAYGYYTGEPSKRSRGALGSI
70 80 90 100 110 120
130 140 150
pF1KE1 ALLGLVGTTVCSAFQHLGWVKSGLGSGPKCCH
::::::::::::::::::::::::::::::::
XP_005 ALLGLVGTTVCSAFQHLGWVKSGLGSGPKCCH
130 140 150
>>NP_004519 (OMIM: 604564) microsomal glutathione S-tran (152 aa)
initn: 1030 init1: 1030 opt: 1030 Z-score: 1394.0 bits: 264.0 E(85289): 6.6e-71
Smith-Waterman score: 1030; 100.0% identity (100.0% similar) in 152 aa overlap (1-152:1-152)
10 20 30 40 50 60
pF1KE1 MAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCIQRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCIQRA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 HQNTLEVYPPFLFFLAVGGVYHPRIASGLGLAWIVGRVLYAYGYYTGEPSKRSRGALGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HQNTLEVYPPFLFFLAVGGVYHPRIASGLGLAWIVGRVLYAYGYYTGEPSKRSRGALGSI
70 80 90 100 110 120
130 140 150
pF1KE1 ALLGLVGTTVCSAFQHLGWVKSGLGSGPKCCH
::::::::::::::::::::::::::::::::
NP_004 ALLGLVGTTVCSAFQHLGWVKSGLGSGPKCCH
130 140 150
>>NP_002404 (OMIM: 601733) microsomal glutathione S-tran (147 aa)
initn: 141 init1: 77 opt: 209 Z-score: 290.1 bits: 59.7 E(85289): 2e-09
Smith-Waterman score: 209; 38.9% identity (65.9% similar) in 126 aa overlap (9-127:3-122)
10 20 30 40 50
pF1KE1 MAVLSKEYGFVLLTGAASFIMV---AHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCI
: .: .:.:.. . ...:..:.::: :::: : . . .:: ..:
NP_002 MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAV-TGSPEFERVF---
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 QRAHQNTLEVYPPFLFFLAVGGVYHPRI-ASGLGLAWIVGRVLYAYGYYTGEPSKRSRG-
::.:: .: :: :.. : ..: : .. :. :::..: :: :: .:: . .:: :
NP_002 -RAQQNCVEFYPIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGY-SEAAKKRITGF
60 70 80 90 100
120 130 140 150
pF1KE1 --ALGSIALLGLVGTTVCSAFQHLGWVKSGLGSGPKCCH
.:: .::: :.:
NP_002 RLSLGILALLTLLGALGIANSFLDEYLDLNIAKKLRRQF
110 120 130 140
>>XP_016863702 (OMIM: 601733) PREDICTED: microsomal glut (147 aa)
initn: 141 init1: 77 opt: 209 Z-score: 290.1 bits: 59.7 E(85289): 2e-09
Smith-Waterman score: 209; 38.9% identity (65.9% similar) in 126 aa overlap (9-127:3-122)
10 20 30 40 50
pF1KE1 MAVLSKEYGFVLLTGAASFIMV---AHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCI
: .: .:.:.. . ...:..:.::: :::: : . . .:: ..:
XP_016 MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAV-TGSPEFERVF---
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 QRAHQNTLEVYPPFLFFLAVGGVYHPRI-ASGLGLAWIVGRVLYAYGYYTGEPSKRSRG-
::.:: .: :: :.. : ..: : .. :. :::..: :: :: .:: . .:: :
XP_016 -RAQQNCVEFYPIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGY-SEAAKKRITGF
60 70 80 90 100
120 130 140 150
pF1KE1 --ALGSIALLGLVGTTVCSAFQHLGWVKSGLGSGPKCCH
.:: .::: :.:
XP_016 RLSLGILALLTLLGALGIANSFLDEYLDLNIAKKLRRQF
110 120 130 140
>>XP_016863701 (OMIM: 601733) PREDICTED: microsomal glut (147 aa)
initn: 141 init1: 77 opt: 209 Z-score: 290.1 bits: 59.7 E(85289): 2e-09
Smith-Waterman score: 209; 38.9% identity (65.9% similar) in 126 aa overlap (9-127:3-122)
10 20 30 40 50
pF1KE1 MAVLSKEYGFVLLTGAASFIMV---AHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCI
: .: .:.:.. . ...:..:.::: :::: : . . .:: ..:
XP_016 MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAV-TGSPEFERVF---
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 QRAHQNTLEVYPPFLFFLAVGGVYHPRI-ASGLGLAWIVGRVLYAYGYYTGEPSKRSRG-
::.:: .: :: :.. : ..: : .. :. :::..: :: :: .:: . .:: :
XP_016 -RAQQNCVEFYPIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGY-SEAAKKRITGF
60 70 80 90 100
120 130 140 150
pF1KE1 --ALGSIALLGLVGTTVCSAFQHLGWVKSGLGSGPKCCH
.:: .::: :.:
XP_016 RLSLGILALLTLLGALGIANSFLDEYLDLNIAKKLRRQF
110 120 130 140
>>XP_016863700 (OMIM: 601733) PREDICTED: microsomal glut (147 aa)
initn: 141 init1: 77 opt: 209 Z-score: 290.1 bits: 59.7 E(85289): 2e-09
Smith-Waterman score: 209; 38.9% identity (65.9% similar) in 126 aa overlap (9-127:3-122)
10 20 30 40 50
pF1KE1 MAVLSKEYGFVLLTGAASFIMV---AHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCI
: .: .:.:.. . ...:..:.::: :::: : . . .:: ..:
XP_016 MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAV-TGSPEFERVF---
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 QRAHQNTLEVYPPFLFFLAVGGVYHPRI-ASGLGLAWIVGRVLYAYGYYTGEPSKRSRG-
::.:: .: :: :.. : ..: : .. :. :::..: :: :: .:: . .:: :
XP_016 -RAQQNCVEFYPIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGY-SEAAKKRITGF
60 70 80 90 100
120 130 140 150
pF1KE1 --ALGSIALLGLVGTTVCSAFQHLGWVKSGLGSGPKCCH
.:: .::: :.:
XP_016 RLSLGILALLTLLGALGIANSFLDEYLDLNIAKKLRRQF
110 120 130 140
>>NP_001191295 (OMIM: 601733) microsomal glutathione S-t (147 aa)
initn: 141 init1: 77 opt: 209 Z-score: 290.1 bits: 59.7 E(85289): 2e-09
Smith-Waterman score: 209; 38.9% identity (65.9% similar) in 126 aa overlap (9-127:3-122)
10 20 30 40 50
pF1KE1 MAVLSKEYGFVLLTGAASFIMV---AHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCI
: .: .:.:.. . ...:..:.::: :::: : . . .:: ..:
NP_001 MAGNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAV-TGSPEFERVF---
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 QRAHQNTLEVYPPFLFFLAVGGVYHPRI-ASGLGLAWIVGRVLYAYGYYTGEPSKRSRG-
::.:: .: :: :.. : ..: : .. :. :::..: :: :: .:: . .:: :
NP_001 -RAQQNCVEFYPIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGY-SEAAKKRITGF
60 70 80 90 100
120 130 140 150
pF1KE1 --ALGSIALLGLVGTTVCSAFQHLGWVKSGLGSGPKCCH
.:: .::: :.:
NP_001 RLSLGILALLTLLGALGIANSFLDEYLDLNIAKKLRRQF
110 120 130 140
>>NP_665874 (OMIM: 246530,614037) leukotriene C4 synthas (150 aa)
initn: 75 init1: 48 opt: 135 Z-score: 190.5 bits: 41.3 E(85289): 0.00072
Smith-Waterman score: 137; 29.1% identity (58.1% similar) in 148 aa overlap (11-144:5-147)
10 20 30 40 50
pF1KE1 MAVLSKEYGFVLLTGAASFIMV---AHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCI
: : .:.... : :.....: .::. ..: :. .: : . :. .
NP_665 MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPL--TTGPPE---FERV
10 20 30 40
60 70 80 90 100
pF1KE1 QRAHQNTLEVYPPFLFFLAVGGVY-HPRIASGLGLAWIVGRVLYAYGYYTGE-----P--
::. : : .: :: : :.:.. : :. ::... .:. : :: . :
NP_665 YRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLY
50 60 70 80 90 100
110 120 130 140 150
pF1KE1 -SKRSRGALGSIALLGLVGTTVCSAFQH--LGWVKSGLGSGPKCCH
: :. : ..: :::.. . .:.. :: ... :
NP_665 ASARALWLLVALAALGLLAHFLPAALRAALLGRLRTLLPWA
110 120 130 140 150
152 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 18:50:14 2016 done: Sun Nov 6 18:50:15 2016
Total Scan time: 4.500 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]