FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE9283, 192 aa
  1>>>pF1KE9283 192 - 192 aa - 192 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.8976+/-0.000323; mu= 14.8815+/- 0.020
 mean_var=58.5608+/-11.406, 0's: 0 Z-trim(114.7): 15  B-trim: 0 in 0/54
 Lambda= 0.167599
 statistics sampled from 24702 (24706) to 24702 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.29), width:  16
 Scan time:  5.370

The best scores are:                                      opt bits E(85289)
NP_006547 (OMIM: 175800,607622) phosphomevalonate  ( 192) 1299 322.1 3.5e-88
NP_001309940 (OMIM: 175800,607622) phosphomevalona ( 178) 1112 276.8 1.4e-74
NP_001309941 (OMIM: 175800,607622) phosphomevalona ( 117)  811 203.9 7.8e-53


>>NP_006547 (OMIM: 175800,607622) phosphomevalonate kina  (192 aa)
 initn: 1299 init1: 1299 opt: 1299  Z-score: 1704.1  bits: 322.1 E(85289): 3.5e-88
Smith-Waterman score: 1299; 100.0% identity (100.0% similar) in 192 aa overlap (1-192:1-192)

               10        20        30        40        50        60
pF1KE9 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE9 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE9 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
              130       140       150       160       170       180

              190  
pF1KE9 LENLIEFIRSRL
       ::::::::::::
NP_006 LENLIEFIRSRL
              190  

>>NP_001309940 (OMIM: 175800,607622) phosphomevalonate k  (178 aa)
 initn: 1112 init1: 1112 opt: 1112  Z-score: 1460.2  bits: 276.8 E(85289): 1.4e-74
Smith-Waterman score: 1112; 96.4% identity (98.2% similar) in 169 aa overlap (24-192:10-178)

               10        20        30        40        50        60
pF1KE9 MAPLGGAPRLVLLFSGKRKSGKDFVTEALQSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
                              .. :  .::::::::::::::::::::::::::::::
NP_001               MPPLHKTVVYTGEPQRSRLGADVCAVLRLSGPLKEQYAQEHGLNFQ
                             10        20        30        40      

               70        80        90       100       110       120
pF1KE9 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWLVSDTRRVSDIQWFRE
         50        60        70        80        90       100      

              130       140       150       160       170       180
pF1KE9 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFDWVIENHGVEQRLEEQ
        110       120       130       140       150       160      

              190  
pF1KE9 LENLIEFIRSRL
       ::::::::::::
NP_001 LENLIEFIRSRL
        170        

>>NP_001309941 (OMIM: 175800,607622) phosphomevalonate k  (117 aa)
 initn: 811 init1: 811 opt: 811  Z-score: 1069.5  bits: 203.9 E(85289): 7.8e-53
Smith-Waterman score: 811; 100.0% identity (100.0% similar) in 117 aa overlap (76-192:1-117)

          50        60        70        80        90       100     
pF1KE9 PLKEQYAQEHGLNFQRLLDTSTYKEAFRKDMIRWGEEKRQADPGFFCRKIVEGISQPIWL
                                     ::::::::::::::::::::::::::::::
NP_001                               MIRWGEEKRQADPGFFCRKIVEGISQPIWL
                                             10        20        30

         110       120       130       140       150       160     
pF1KE9 VSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSDTRRVSDIQWFREAYGAVTQTVRVVALEQSRQQRGWVFTPGVDDAESECGLDNFGDFD
               40        50        60        70        80        90

         170       180       190  
pF1KE9 WVIENHGVEQRLEEQLENLIEFIRSRL
       :::::::::::::::::::::::::::
NP_001 WVIENHGVEQRLEEQLENLIEFIRSRL
              100       110       




192 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 10:19:44 2016 done: Tue Nov  8 10:19:45 2016
 Total Scan time:  5.370 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]