Result of FASTA (omim) for
pFN21AE2372
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2372, 657 aa
1>>>pF1KE2372 657 - 657 aa - 657 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.1108+/-0.000604; mu= -34.7386+/- 0.037
mean_var=639.6366+/-132.341, 0's: 0 Z-trim(116.8): 33 B-trim: 376 in 1/56
Lambda= 0.050712
statistics sampled from 28309 (28334) to 28309 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.332), width: 16
Scan time: 13.020
The best scores are: opt bits E(85289)
NP_919268 (OMIM: 609321,616402) spindle assembly a ( 657) 4194 322.9 2.3e-87
XP_016855975 (OMIM: 609321,616402) PREDICTED: spin ( 630) 4009 309.3 2.7e-83
NP_001291758 (OMIM: 609321,616402) spindle assembl ( 490) 3095 242.4 3e-63
>>NP_919268 (OMIM: 609321,616402) spindle assembly abnor (657 aa)
initn: 4194 init1: 4194 opt: 4194 Z-score: 1689.3 bits: 322.9 E(85289): 2.3e-87
Smith-Waterman score: 4194; 99.8% identity (100.0% similar) in 657 aa overlap (1-657:1-657)
10 20 30 40 50 60
pF1KE2 MSQVLFHQLVPLQVKCKDCEERRVSIRMSIELQSVSNPVHRKDLVIRLTDDTDPFFLYNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 MSQVLFHQLVPLQVKCKDCEERRVSIRMSIELQSVSNPVHRKDLVIRLTDDTDPFFLYNL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 VISEEDFQSLKFQQGLLVDFLAFPQKFIDLLQQCTQEHAKEIPRFLLQLVSPAAILDNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 VISEEDFQSLKFQQGLLVDFLAFPQKFIDLLQQCTQEHAKEIPRFLLQLVSPAAILDNSP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 AFLNVVETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 AFLNVVETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 TRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 TRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 ILHQQNIHQLQNRLSELEVANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLR
::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
NP_919 ILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 RENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 RENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 KNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 KNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE2 KLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 KLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE2 NQLVRKQDVLGPSTTPPAHSSSNTIRSGISPNLNVVDGRLTYPTCGIGYPVSSAFAFQNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 NQLVRKQDVLGPSTTPPAHSSSNTIRSGISPNLNVVDGRLTYPTCGIGYPVSSAFAFQNT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE2 FPHSISAKNTSHPGSGTKVQFNLQFTKPNASLGDVQSGATISMPCSTDKENGENVGLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 FPHSISAKNTSHPGSGTKVQFNLQFTKPNASLGDVQSGATISMPCSTDKENGENVGLESK
550 560 570 580 590 600
610 620 630 640 650
pF1KE2 YLKKREDSIPLRGLSQNLFSNSDHQRDGTLGALHTSSKPTALPSASSAYFPGQLPNS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_919 YLKKREDSIPLRGLSQNLFSNSDHQRDGTLGALHTSSKPTALPSASSAYFPGQLPNS
610 620 630 640 650
>>XP_016855975 (OMIM: 609321,616402) PREDICTED: spindle (630 aa)
initn: 4009 init1: 4009 opt: 4009 Z-score: 1616.4 bits: 309.3 E(85289): 2.7e-83
Smith-Waterman score: 4009; 99.8% identity (100.0% similar) in 630 aa overlap (28-657:1-630)
10 20 30 40 50 60
pF1KE2 MSQVLFHQLVPLQVKCKDCEERRVSIRMSIELQSVSNPVHRKDLVIRLTDDTDPFFLYNL
:::::::::::::::::::::::::::::::::
XP_016 MSIELQSVSNPVHRKDLVIRLTDDTDPFFLYNL
10 20 30
70 80 90 100 110 120
pF1KE2 VISEEDFQSLKFQQGLLVDFLAFPQKFIDLLQQCTQEHAKEIPRFLLQLVSPAAILDNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VISEEDFQSLKFQQGLLVDFLAFPQKFIDLLQQCTQEHAKEIPRFLLQLVSPAAILDNSP
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 AFLNVVETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFLNVVETNPFKHLTHLSLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDF
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE2 TRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRKTLAEKKQELDKLRNEWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLE
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE2 ILHQQNIHQLQNRLSELEVANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLR
::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
XP_016 ILHQQNIHQLQNRLSELEAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLR
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE2 RENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RENSTLDVECHEKEKHVNQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGE
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE2 KNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNQVQLGKLEATIKSLSAELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEE
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE2 KLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLQKEQKELQDVGQSLRIKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNE
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE2 NQLVRKQDVLGPSTTPPAHSSSNTIRSGISPNLNVVDGRLTYPTCGIGYPVSSAFAFQNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQLVRKQDVLGPSTTPPAHSSSNTIRSGISPNLNVVDGRLTYPTCGIGYPVSSAFAFQNT
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE2 FPHSISAKNTSHPGSGTKVQFNLQFTKPNASLGDVQSGATISMPCSTDKENGENVGLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPHSISAKNTSHPGSGTKVQFNLQFTKPNASLGDVQSGATISMPCSTDKENGENVGLESK
520 530 540 550 560 570
610 620 630 640 650
pF1KE2 YLKKREDSIPLRGLSQNLFSNSDHQRDGTLGALHTSSKPTALPSASSAYFPGQLPNS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLKKREDSIPLRGLSQNLFSNSDHQRDGTLGALHTSSKPTALPSASSAYFPGQLPNS
580 590 600 610 620 630
>>NP_001291758 (OMIM: 609321,616402) spindle assembly ab (490 aa)
initn: 3095 init1: 3095 opt: 3095 Z-score: 1256.6 bits: 242.4 E(85289): 3e-63
Smith-Waterman score: 3095; 99.8% identity (100.0% similar) in 490 aa overlap (168-657:1-490)
140 150 160 170 180 190
pF1KE2 SLKLLPGNDVEIKKFLAGCLKCSKEEKLSLMQSLDDATKQLDFTRKTLAEKKQELDKLRN
::::::::::::::::::::::::::::::
NP_001 MQSLDDATKQLDFTRKTLAEKKQELDKLRN
10 20 30
200 210 220 230 240 250
pF1KE2 EWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EWASHTAALTNKHSQELTNEKEKALQAQVQYQQQHEQQKKDLEILHQQNIHQLQNRLSEL
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE2 EVANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHV
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EAANKDLTERKYKGDSTIRELKAKLSGVEEELQRTKQEVLSLRRENSTLDVECHEKEKHV
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE2 NQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQLQTKVAVLEQEIKDKDQLVLRTKEAFDTIQEQKVVLEENGEKNQVQLGKLEATIKSLS
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE2 AELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AELLKANEIIKKLQGDLKTLMGKLKLKNTVTIQQEKLLAEKEEKLQKEQKELQDVGQSLR
220 230 240 250 260 270
440 450 460 470 480 490
pF1KE2 IKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQDVLGPSTTPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKEQEVCKLQEQLEATVKKLEESKQLLKNNEKLITWLNKELNENQLVRKQDVLGPSTTPP
280 290 300 310 320 330
500 510 520 530 540 550
pF1KE2 AHSSSNTIRSGISPNLNVVDGRLTYPTCGIGYPVSSAFAFQNTFPHSISAKNTSHPGSGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHSSSNTIRSGISPNLNVVDGRLTYPTCGIGYPVSSAFAFQNTFPHSISAKNTSHPGSGT
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE2 KVQFNLQFTKPNASLGDVQSGATISMPCSTDKENGENVGLESKYLKKREDSIPLRGLSQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVQFNLQFTKPNASLGDVQSGATISMPCSTDKENGENVGLESKYLKKREDSIPLRGLSQN
400 410 420 430 440 450
620 630 640 650
pF1KE2 LFSNSDHQRDGTLGALHTSSKPTALPSASSAYFPGQLPNS
::::::::::::::::::::::::::::::::::::::::
NP_001 LFSNSDHQRDGTLGALHTSSKPTALPSASSAYFPGQLPNS
460 470 480 490
657 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 19:12:17 2016 done: Sun Nov 6 19:12:19 2016
Total Scan time: 13.020 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]