Result of FASTA (ccds) for
pFN21AE3041
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3041, 178 aa
1>>>pF1KE3041 178 - 178 aa - 178 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8830+/-0.000616; mu= 16.2526+/- 0.037
mean_var=74.5446+/-14.765, 0's: 0 Z-trim(112.9): 8 B-trim: 83 in 2/49
Lambda= 0.148548
statistics sampled from 13555 (13562) to 13555 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.789), E-opt: 0.2 (0.417), width: 16
Scan time: 2.150
The best scores are: opt bits E(32554)
CCDS462.1 EDN2 gene_id:1907|Hs108|chr1 ( 178) 1242 274.3 2.7e-74
CCDS4522.1 EDN1 gene_id:1906|Hs108|chr6 ( 212) 276 67.4 6.5e-12
CCDS77597.1 EDN3 gene_id:1908|Hs108|chr20 ( 192) 268 65.6 2e-11
CCDS13479.1 EDN3 gene_id:1908|Hs108|chr20 ( 219) 268 65.7 2.2e-11
CCDS13478.1 EDN3 gene_id:1908|Hs108|chr20 ( 224) 268 65.7 2.2e-11
CCDS13477.1 EDN3 gene_id:1908|Hs108|chr20 ( 238) 268 65.7 2.3e-11
>>CCDS462.1 EDN2 gene_id:1907|Hs108|chr1 (178 aa)
initn: 1242 init1: 1242 opt: 1242 Z-score: 1447.2 bits: 274.3 E(32554): 2.7e-74
Smith-Waterman score: 1242; 100.0% identity (100.0% similar) in 178 aa overlap (1-178:1-178)
10 20 30 40 50 60
pF1KE3 MVSVPTTWCSVALALLVALHEGKGQAAATLEQPASSSHAQGTHLRLRRCSCSSWLDKECV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MVSVPTTWCSVALALLVALHEGKGQAAATLEQPASSSHAQGTHLRLRRCSCSSWLDKECV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 YFCHLDIIWVNTPEQTAPYGLGNPPRRRRRSLPRRCQCSSARDPACATFCLRRPWTEAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 YFCHLDIIWVNTPEQTAPYGLGNPPRRRRRSLPRRCQCSSARDPACATFCLRRPWTEAGA
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 VPSRKSPADVFQTGKTGATTGELLQRLRDISTVKSLFAKRQQEAMREPRSTHSRWRKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 VPSRKSPADVFQTGKTGATTGELLQRLRDISTVKSLFAKRQQEAMREPRSTHSRWRKR
130 140 150 160 170
>>CCDS4522.1 EDN1 gene_id:1906|Hs108|chr6 (212 aa)
initn: 341 init1: 254 opt: 276 Z-score: 327.4 bits: 67.4 E(32554): 6.5e-12
Smith-Waterman score: 323; 38.4% identity (56.7% similar) in 164 aa overlap (45-175:49-212)
20 30 40 50 60 70
pF1KE3 LLVALHEGKGQAAATLEQPASSSHAQGTHLRLRRCSCSSWLDKECVYFCHLDIIWVNTPE
: .:::::: .:::::::::::::::::::
CCDS45 PETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMDKECVYFCHLDIIWVNTPE
20 30 40 50 60 70
80 90 100 110
pF1KE3 QTAPYGLGNPPRRR--RRSLPR-------RCQCSSARDPACATFC-----------LRRP
...:::::.: .: . :: ::::.: .: : .:: ...
CCDS45 HVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCWNFCQAGKELRAEDIMEKD
80 90 100 110 120 130
120 130 140 150 160
pF1KE3 WT--EAGAVPSRKSPADVFQTGKTGA----TTGELLQRLRDIS---TVKSLF--AKRQQE
:. . : :. . ..: : .. : :.. :. . .::: : : . .
CCDS45 WNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSETMRNSVKSSFHDPKLKGK
140 150 160 170 180 190
170
pF1KE3 AMREPRSTHSR--WRKR
:: ::.: :
CCDS45 PSRERYVTHNRAHW
200 210
>>CCDS77597.1 EDN3 gene_id:1908|Hs108|chr20 (192 aa)
initn: 288 init1: 233 opt: 268 Z-score: 318.7 bits: 65.6 E(32554): 2e-11
Smith-Waterman score: 291; 45.5% identity (59.8% similar) in 112 aa overlap (22-110:62-173)
10 20 30 40
pF1KE3 MVSVPTTWCSVALALLVALHEGKGQAAATLEQ------PASSSHAQGT--H
:.: .: : : :.. . :.:. :
CCDS77 GVSQAPTAARSEGDCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEGAPEH
40 50 60 70 80 90
50 60 70 80 90
pF1KE3 LRLRRCSCSSWLDKECVYFCHLDIIWVNTPEQTAPYGLGN--PPRRRRRS---LPR----
: :::.: .. ::::::.:::::::.::::::.::::.: : .:: ::
CCDS77 HRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRSAGPLPGNLQL
100 110 120 130 140 150
100 110 120 130 140
pF1KE3 ------RCQCSSARDPACATFCLRRPWTEAGAVPSRKSPADVFQTGKTGATTGELLQRLR
:: : . : :: ::
CCDS77 SHRPHLRCACVGRYDKACLHFCTQTLDVSRLKSRTNKASRL
160 170 180 190
>>CCDS13479.1 EDN3 gene_id:1908|Hs108|chr20 (219 aa)
initn: 288 init1: 233 opt: 268 Z-score: 317.9 bits: 65.7 E(32554): 2.2e-11
Smith-Waterman score: 307; 39.7% identity (58.9% similar) in 151 aa overlap (22-148:62-210)
10 20 30 40
pF1KE3 MVSVPTTWCSVALALLVALHEGKGQAAATLEQ------PASSSHAQGT--H
:.: .: : : :.. . :.:. :
CCDS13 GVSQAPTAARSEGDCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEGAPEH
40 50 60 70 80 90
50 60 70 80 90
pF1KE3 LRLRRCSCSSWLDKECVYFCHLDIIWVNTPEQTAPYGLGN--PPRRRRRS---LPR----
: :::.: .. ::::::.:::::::.::::::.::::.: : .:: ::
CCDS13 HRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRSAGPLPGNLQL
100 110 120 130 140 150
100 110 120 130 140
pF1KE3 ------RCQCSSARDPACATFCLRRPWTEAGAVPSRKSPADVFQTGKT-GATTGELLQRL
:: : . : :: :: . . ... ..:. : . ::. ::. : .::
CCDS13 SHRPHLRCACVGRYDKACLHFCTQTLDVSSNSRTAEKT--DKEEEGKVRGANRGLCQRRL
160 170 180 190 200
150 160 170
pF1KE3 RDISTVKSLFAKRQQEAMREPRSTHSRWRKR
.
CCDS13 KSRTNKASRL
210
>>CCDS13478.1 EDN3 gene_id:1908|Hs108|chr20 (224 aa)
initn: 288 init1: 233 opt: 268 Z-score: 317.8 bits: 65.7 E(32554): 2.2e-11
Smith-Waterman score: 291; 45.5% identity (59.8% similar) in 112 aa overlap (22-110:62-173)
10 20 30 40
pF1KE3 MVSVPTTWCSVALALLVALHEGKGQAAATLEQ------PASSSHAQGT--H
:.: .: : : :.. . :.:. :
CCDS13 GVSQAPTAARSEGDCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEGAPEH
40 50 60 70 80 90
50 60 70 80 90
pF1KE3 LRLRRCSCSSWLDKECVYFCHLDIIWVNTPEQTAPYGLGN--PPRRRRRS---LPR----
: :::.: .. ::::::.:::::::.::::::.::::.: : .:: ::
CCDS13 HRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRSAGPLPGNLQL
100 110 120 130 140 150
100 110 120 130 140
pF1KE3 ------RCQCSSARDPACATFCLRRPWTEAGAVPSRKSPADVFQTGKTGATTGELLQRLR
:: : . : :: ::
CCDS13 SHRPHLRCACVGRYDKACLHFCTQTLDVSRQVEVKDQQSKQALDLHHPKLMPGSGLALAP
160 170 180 190 200 210
>>CCDS13477.1 EDN3 gene_id:1908|Hs108|chr20 (238 aa)
initn: 288 init1: 233 opt: 268 Z-score: 317.5 bits: 65.7 E(32554): 2.3e-11
Smith-Waterman score: 291; 45.5% identity (59.8% similar) in 112 aa overlap (22-110:62-173)
10 20 30 40
pF1KE3 MVSVPTTWCSVALALLVALHEGKGQAAATLEQ------PASSSHAQGT--H
:.: .: : : :.. . :.:. :
CCDS13 GVSQAPTAARSEGDCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEGAPEH
40 50 60 70 80 90
50 60 70 80 90
pF1KE3 LRLRRCSCSSWLDKECVYFCHLDIIWVNTPEQTAPYGLGN--PPRRRRRS---LPR----
: :::.: .. ::::::.:::::::.::::::.::::.: : .:: ::
CCDS13 HRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRSAGPLPGNLQL
100 110 120 130 140 150
100 110 120 130 140
pF1KE3 ------RCQCSSARDPACATFCLRRPWTEAGAVPSRKSPADVFQTGKTGATTGELLQRLR
:: : . : :: ::
CCDS13 SHRPHLRCACVGRYDKACLHFCTQTLDVSSNSRTAEKTDKEEEGKVEVKDQQSKQALDLH
160 170 180 190 200 210
178 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:55:43 2016 done: Sun Nov 6 04:55:44 2016
Total Scan time: 2.150 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]