Result of FASTA (omim) for
pFN21AE2616
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2616, 450 aa
1>>>pF1KE2616 450 - 450 aa - 450 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.1929+/-0.000315; mu= 5.4627+/- 0.020
mean_var=168.4214+/-34.464, 0's: 0 Z-trim(121.8): 44 B-trim: 430 in 2/55
Lambda= 0.098827
statistics sampled from 38876 (38920) to 38876 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.779), E-opt: 0.2 (0.456), width: 16
Scan time: 7.020
The best scores are: opt bits E(85289)
NP_001119713 (OMIM: 601990) tumor protein p73 isof ( 450) 3096 453.1 6.9e-127
NP_001119712 (OMIM: 601990) tumor protein p73 isof ( 587) 3051 446.8 7.4e-125
NP_001191113 (OMIM: 601990) tumor protein p73 isof ( 499) 3008 440.6 4.5e-123
NP_005418 (OMIM: 601990) tumor protein p73 isoform ( 636) 2963 434.2 4.7e-121
NP_001191121 (OMIM: 601990) tumor protein p73 isof ( 565) 2911 426.8 7.3e-119
NP_001119714 (OMIM: 601990) tumor protein p73 isof ( 426) 2386 351.9 2e-96
NP_001191119 (OMIM: 601990) tumor protein p73 isof ( 506) 2386 351.9 2.3e-96
NP_001191118 (OMIM: 601990) tumor protein p73 isof ( 354) 2371 349.7 7.5e-96
NP_001191120 (OMIM: 601990) tumor protein p73 isof ( 491) 2369 349.5 1.2e-95
NP_001191114 (OMIM: 601990) tumor protein p73 isof ( 475) 2298 339.3 1.3e-92
NP_001191116 (OMIM: 601990) tumor protein p73 isof ( 555) 2298 339.4 1.5e-92
NP_001191115 (OMIM: 601990) tumor protein p73 isof ( 403) 2283 337.2 5e-92
NP_001191117 (OMIM: 601990) tumor protein p73 isof ( 540) 2281 336.9 7.7e-92
NP_001108453 (OMIM: 103285,106260,129400,603273,60 ( 461) 1870 278.3 3e-74
NP_001108450 (OMIM: 103285,106260,129400,603273,60 ( 555) 1864 277.5 6.2e-74
NP_001108452 (OMIM: 103285,106260,129400,603273,60 ( 586) 1849 275.4 2.9e-73
XP_005247901 (OMIM: 103285,106260,129400,603273,60 ( 663) 1843 274.6 5.7e-73
NP_001316893 (OMIM: 103285,106260,129400,603273,60 ( 678) 1843 274.6 5.8e-73
XP_011511553 (OMIM: 103285,106260,129400,603273,60 ( 679) 1843 274.6 5.8e-73
NP_003713 (OMIM: 103285,106260,129400,603273,60354 ( 680) 1843 274.6 5.8e-73
XP_016862876 (OMIM: 103285,106260,129400,603273,60 ( 582) 1822 271.5 4.1e-72
NP_001316077 (OMIM: 103285,106260,129400,603273,60 ( 676) 1816 270.7 8.4e-72
NP_001316074 (OMIM: 103285,106260,129400,603273,60 ( 416) 1748 260.9 4.7e-69
NP_001316073 (OMIM: 103285,106260,129400,603273,60 ( 510) 1742 260.1 1e-68
NP_001316078 (OMIM: 103285,106260,129400,603273,60 ( 412) 1721 257.0 6.7e-68
NP_001108454 (OMIM: 103285,106260,129400,603273,60 ( 393) 1629 243.9 5.7e-64
NP_001108451 (OMIM: 103285,106260,129400,603273,60 ( 487) 1623 243.1 1.2e-63
NP_001316075 (OMIM: 103285,106260,129400,603273,60 ( 501) 1494 224.7 4.3e-58
NP_001316079 (OMIM: 103285,106260,129400,603273,60 ( 327) 1366 206.3 9.6e-53
NP_001263690 (OMIM: 114480,114500,114550,137800,15 ( 354) 935 144.9 3.2e-34
NP_001263689 (OMIM: 114480,114500,114550,137800,15 ( 354) 935 144.9 3.2e-34
NP_001119590 (OMIM: 114480,114500,114550,137800,15 ( 354) 935 144.9 3.2e-34
NP_000537 (OMIM: 114480,114500,114550,137800,15162 ( 393) 935 144.9 3.5e-34
NP_001119584 (OMIM: 114480,114500,114550,137800,15 ( 393) 935 144.9 3.5e-34
NP_001263624 (OMIM: 114480,114500,114550,137800,15 ( 307) 861 134.3 4.3e-31
NP_001263625 (OMIM: 114480,114500,114550,137800,15 ( 302) 860 134.2 4.7e-31
NP_001119585 (OMIM: 114480,114500,114550,137800,15 ( 346) 861 134.4 4.7e-31
NP_001119586 (OMIM: 114480,114500,114550,137800,15 ( 341) 860 134.2 5.2e-31
NP_001119587 (OMIM: 114480,114500,114550,137800,15 ( 261) 798 125.3 1.9e-28
NP_001119589 (OMIM: 114480,114500,114550,137800,15 ( 214) 724 114.7 2.4e-25
NP_001119588 (OMIM: 114480,114500,114550,137800,15 ( 209) 723 114.5 2.6e-25
NP_001263626 (OMIM: 114480,114500,114550,137800,15 ( 234) 657 105.2 2e-22
NP_001263628 (OMIM: 114480,114500,114550,137800,15 ( 187) 583 94.6 2.5e-19
NP_001263627 (OMIM: 114480,114500,114550,137800,15 ( 182) 582 94.4 2.7e-19
>>NP_001119713 (OMIM: 601990) tumor protein p73 isoform (450 aa)
initn: 3096 init1: 3096 opt: 3096 Z-score: 2399.0 bits: 453.1 E(85289): 6.9e-127
Smith-Waterman score: 3096; 100.0% identity (100.0% similar) in 450 aa overlap (1-450:1-450)
10 20 30 40 50 60
pF1KE2 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 FEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 GDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 VLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSS
370 380 390 400 410 420
430 440 450
pF1KE2 HSAQSMVSGSHCTPPPPYHADPSLVRTWGP
::::::::::::::::::::::::::::::
NP_001 HSAQSMVSGSHCTPPPPYHADPSLVRTWGP
430 440 450
>>NP_001119712 (OMIM: 601990) tumor protein p73 isoform (587 aa)
initn: 3051 init1: 3051 opt: 3051 Z-score: 2362.6 bits: 446.8 E(85289): 7.4e-125
Smith-Waterman score: 3051; 100.0% identity (100.0% similar) in 445 aa overlap (1-445:1-445)
10 20 30 40 50 60
pF1KE2 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 FEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 GDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 VLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSS
370 380 390 400 410 420
430 440 450
pF1KE2 HSAQSMVSGSHCTPPPPYHADPSLVRTWGP
:::::::::::::::::::::::::
NP_001 HSAQSMVSGSHCTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQGLQSIYHLQNLTIEDLG
430 440 450 460 470 480
>>NP_001191113 (OMIM: 601990) tumor protein p73 isoform (499 aa)
initn: 3008 init1: 3008 opt: 3008 Z-score: 2330.5 bits: 440.6 E(85289): 4.5e-123
Smith-Waterman score: 3008; 100.0% identity (100.0% similar) in 437 aa overlap (14-450:63-499)
10 20 30 40
pF1KE2 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAAS
::::::::::::::::::::::::::::::
NP_001 QSSRGNNEVVGGTDSSMDVFHLEGMTTSVMAQFNLLSSTMDQMSSRAASASPYTPEHAAS
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE2 VPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLY
100 110 120 130 140 150
110 120 130 140 150 160
pF1KE2 CQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPAS
160 170 180 190 200 210
170 180 190 200 210 220
pF1KE2 HLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPIL
220 230 240 250 260 270
230 240 250 260 270 280
pF1KE2 IIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQ
280 290 300 310 320 330
290 300 310 320 330 340
pF1KE2 SPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQ
340 350 360 370 380 390
350 360 370 380 390 400
pF1KE2 QQLLQRPSHLQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQLLQRPSHLQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGM
400 410 420 430 440 450
410 420 430 440 450
pF1KE2 LNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVRTWGP
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVRTWGP
460 470 480 490
>>NP_005418 (OMIM: 601990) tumor protein p73 isoform a [ (636 aa)
initn: 2963 init1: 2963 opt: 2963 Z-score: 2294.3 bits: 434.2 E(85289): 4.7e-121
Smith-Waterman score: 2963; 100.0% identity (100.0% similar) in 432 aa overlap (14-445:63-494)
10 20 30 40
pF1KE2 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAAS
::::::::::::::::::::::::::::::
NP_005 QSSRGNNEVVGGTDSSMDVFHLEGMTTSVMAQFNLLSSTMDQMSSRAASASPYTPEHAAS
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE2 VPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLY
100 110 120 130 140 150
110 120 130 140 150 160
pF1KE2 CQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPAS
160 170 180 190 200 210
170 180 190 200 210 220
pF1KE2 HLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 HLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPIL
220 230 240 250 260 270
230 240 250 260 270 280
pF1KE2 IIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQ
280 290 300 310 320 330
290 300 310 320 330 340
pF1KE2 SPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQ
340 350 360 370 380 390
350 360 370 380 390 400
pF1KE2 QQLLQRPSHLQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QQLLQRPSHLQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGM
400 410 420 430 440 450
410 420 430 440 450
pF1KE2 LNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVRTWGP
::::::::::::::::::::::::::::::::::::::::::
NP_005 LNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQ
460 470 480 490 500 510
NP_005 GLQSIYHLQNLTIEDLGALKIPEQYRMTIWRGLQDLKQGHDYSTAQQLLRSSNAATISIG
520 530 540 550 560 570
>>NP_001191121 (OMIM: 601990) tumor protein p73 isoform (565 aa)
initn: 2911 init1: 2911 opt: 2911 Z-score: 2255.0 bits: 426.8 E(85289): 7.3e-119
Smith-Waterman score: 2911; 100.0% identity (100.0% similar) in 423 aa overlap (23-445:1-423)
10 20 30 40 50 60
pF1KE2 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTM
::::::::::::::::::::::::::::::::::::::
NP_001 MDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTM
10 20 30
70 80 90 100 110 120
pF1KE2 SPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPP
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE2 PPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDP
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE2 VTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRS
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE2 FEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRH
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE2 GDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGP
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE2 VLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSS
340 350 360 370 380 390
430 440 450
pF1KE2 HSAQSMVSGSHCTPPPPYHADPSLVRTWGP
:::::::::::::::::::::::::
NP_001 HSAQSMVSGSHCTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQGLQSIYHLQNLTIEDLG
400 410 420 430 440 450
>>NP_001119714 (OMIM: 601990) tumor protein p73 isoform (426 aa)
initn: 2369 init1: 2369 opt: 2386 Z-score: 1852.2 bits: 351.9 E(85289): 2e-96
Smith-Waterman score: 2386; 91.9% identity (93.7% similar) in 394 aa overlap (1-387:1-394)
10 20 30 40 50 60
pF1KE2 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 FEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRH
250 260 270 280 290 300
310 320 330 340 350
pF1KE2 GDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSH--LQP-PS
:::::::::::::::::::::::::::::::::::::::::::::::::: . :: :
NP_001 GDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPPRDAQQPWPR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE2 YGPV----LSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPA
. .:. ::: : :.. : .: :
NP_001 SASQRRDEQQPQRPVHGLGVPLHSATPLPRRPQPRQFFNRIGVSKLHRVFHLPRVTEHLP
370 380 390 400 410 420
420 430 440 450
pF1KE2 NGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVRTWGP
NP_001 PAEPDH
>>NP_001191119 (OMIM: 601990) tumor protein p73 isoform (506 aa)
initn: 2369 init1: 2369 opt: 2386 Z-score: 1851.1 bits: 351.9 E(85289): 2.3e-96
Smith-Waterman score: 2389; 83.6% identity (89.2% similar) in 444 aa overlap (1-430:1-444)
10 20 30 40 50 60
pF1KE2 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 FEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRH
250 260 270 280 290 300
310 320 330 340 350
pF1KE2 GDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSH--LQP-PS
:::::::::::::::::::::::::::::::::::::::::::::::::: . :: :
NP_001 GDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPPRDAQQPWPR
310 320 330 340 350 360
360 370 380 390 400
pF1KE2 YGPV----LSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGP-----VGPGMLN-NH
. .:. ::: : :.. : .: :... .. .. . :. . ..
NP_001 SASQRRDEQQPQRPVHGLGVPLHSATPLPRRPQPRQDLGALKIPEQYRMTIWRGLQDLKQ
370 380 390 400 410 420
410 420 430 440 450
pF1KE2 GHAVP-ANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVRTWGP
:: :. . ::..: ..::
NP_001 GHDYSTAQQLLRSSNAATISIGGSGELQRQRVMEAVHFRVRHTITIPNRGGPGGGPDEWA
430 440 450 460 470 480
>>NP_001191118 (OMIM: 601990) tumor protein p73 isoform (354 aa)
initn: 2427 init1: 2371 opt: 2371 Z-score: 1841.8 bits: 349.7 E(85289): 7.5e-96
Smith-Waterman score: 2371; 99.7% identity (100.0% similar) in 351 aa overlap (1-351:1-351)
10 20 30 40 50 60
pF1KE2 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 FEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 GDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGP
::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_001 GDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPTWGP
310 320 330 340 350
370 380 390 400 410 420
pF1KE2 VLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSS
>>NP_001191120 (OMIM: 601990) tumor protein p73 isoform (491 aa)
initn: 2369 init1: 2369 opt: 2369 Z-score: 1838.2 bits: 349.5 E(85289): 1.2e-95
Smith-Waterman score: 2369; 100.0% identity (100.0% similar) in 350 aa overlap (1-350:1-350)
10 20 30 40 50 60
pF1KE2 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 SPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 PPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 VTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 FEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 GDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGP
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPFLTGLGCPNC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 VLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSS
NP_001 IEYFTSQGLQSIYHLQNLTIEDLGALKIPEQYRMTIWRGLQDLKQGHDYSTAQQLLRSSN
370 380 390 400 410 420
>>NP_001191114 (OMIM: 601990) tumor protein p73 isoform (475 aa)
initn: 2281 init1: 2281 opt: 2298 Z-score: 1783.7 bits: 339.3 E(85289): 1.3e-92
Smith-Waterman score: 2298; 91.6% identity (93.4% similar) in 381 aa overlap (14-387:63-443)
10 20 30 40
pF1KE2 MLYVGDPARHLATAQFNLLSSTMDQMSSRAASASPYTPEHAAS
::::::::::::::::::::::::::::::
NP_001 QSSRGNNEVVGGTDSSMDVFHLEGMTTSVMAQFNLLSSTMDQMSSRAASASPYTPEHAAS
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE2 VPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLY
100 110 120 130 140 150
110 120 130 140 150 160
pF1KE2 CQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPAS
160 170 180 190 200 210
170 180 190 200 210 220
pF1KE2 HLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPIL
220 230 240 250 260 270
230 240 250 260 270 280
pF1KE2 IIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQ
280 290 300 310 320 330
290 300 310 320 330 340
pF1KE2 SPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQ
340 350 360 370 380 390
350 360 370 380 390
pF1KE2 QQLLQRPSH--LQP-PSYGPV----LSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNL
::::::: . :: : . .:. ::: : :.. : .: :
NP_001 QQLLQRPPRDAQQPWPRSASQRRDEQQPQRPVHGLGVPLHSATPLPRRPQPRQFFNRIGV
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE2 GPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVRTWGP
NP_001 SKLHRVFHLPRVTEHLPPAEPDH
460 470
450 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 17:10:09 2016 done: Tue Nov 8 17:10:10 2016
Total Scan time: 7.020 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]