Result of FASTA (ccds) for
pFN21AE6769
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6769, 534 aa
1>>>pF1KE6769 534 - 534 aa - 534 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8022+/-0.00104; mu= 15.0685+/- 0.062
mean_var=62.9713+/-12.453, 0's: 0 Z-trim(103.0): 47 B-trim: 2 in 1/50
Lambda= 0.161623
statistics sampled from 7166 (7210) to 7166 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.577), E-opt: 0.2 (0.221), width: 16
Scan time: 2.310
The best scores are: opt bits E(32554)
CCDS33405.1 UGT1A4 gene_id:54657|Hs108|chr2 ( 534) 3596 847.6 0
CCDS2509.1 UGT1A3 gene_id:54659|Hs108|chr2 ( 534) 3359 792.3 0
CCDS33404.1 UGT1A5 gene_id:54579|Hs108|chr2 ( 534) 3357 791.9 0
CCDS2510.1 UGT1A1 gene_id:54658|Hs108|chr2 ( 533) 2605 616.5 2.4e-176
CCDS2505.1 UGT1A9 gene_id:54600|Hs108|chr2 ( 530) 2402 569.2 4.2e-162
CCDS33402.1 UGT1A8 gene_id:54576|Hs108|chr2 ( 530) 2396 567.8 1.1e-161
CCDS2507.1 UGT1A6 gene_id:54578|Hs108|chr2 ( 532) 2379 563.8 1.7e-160
CCDS2506.1 UGT1A7 gene_id:54577|Hs108|chr2 ( 530) 2343 555.4 5.8e-158
CCDS33403.1 UGT1A10 gene_id:54575|Hs108|chr2 ( 530) 2339 554.5 1.1e-157
CCDS2508.1 UGT1A6 gene_id:54578|Hs108|chr2 ( 265) 1751 417.3 1.1e-116
CCDS3523.1 UGT2B17 gene_id:7367|Hs108|chr4 ( 530) 1509 361.0 2e-99
CCDS43234.1 UGT2B4 gene_id:7363|Hs108|chr4 ( 528) 1493 357.2 2.6e-98
CCDS75136.1 UGT2B10 gene_id:7365|Hs108|chr4 ( 528) 1485 355.4 9.6e-98
CCDS56331.1 UGT2A2 gene_id:574537|Hs108|chr4 ( 536) 1477 353.5 3.6e-97
CCDS3529.1 UGT2A1 gene_id:10941|Hs108|chr4 ( 527) 1466 350.9 2.1e-96
CCDS3524.1 UGT2B15 gene_id:7366|Hs108|chr4 ( 530) 1466 350.9 2.1e-96
CCDS3526.1 UGT2B7 gene_id:7364|Hs108|chr4 ( 529) 1428 342.1 9.7e-94
CCDS3527.1 UGT2B11 gene_id:10720|Hs108|chr4 ( 529) 1427 341.9 1.1e-93
CCDS3528.1 UGT2B28 gene_id:54490|Hs108|chr4 ( 529) 1412 338.4 1.3e-92
CCDS3525.1 UGT2A3 gene_id:79799|Hs108|chr4 ( 527) 1411 338.1 1.5e-92
CCDS75135.1 UGT2B10 gene_id:7365|Hs108|chr4 ( 444) 1159 279.3 6.2e-75
CCDS58901.1 UGT2A1 gene_id:10941|Hs108|chr4 ( 527) 1099 265.4 1.2e-70
CCDS3705.1 UGT8 gene_id:7368|Hs108|chr4 ( 541) 993 240.7 3.4e-63
CCDS77925.1 UGT2A1 gene_id:10941|Hs108|chr4 ( 483) 858 209.2 9.1e-54
CCDS77924.1 UGT2A2 gene_id:574537|Hs108|chr4 ( 492) 858 209.2 9.2e-54
CCDS58902.1 UGT2A1 gene_id:10941|Hs108|chr4 ( 693) 858 209.2 1.3e-53
CCDS3914.1 UGT3A2 gene_id:167127|Hs108|chr5 ( 523) 841 205.2 1.5e-52
CCDS3913.1 UGT3A1 gene_id:133688|Hs108|chr5 ( 523) 811 198.2 1.9e-50
CCDS54842.1 UGT3A2 gene_id:167127|Hs108|chr5 ( 489) 802 196.1 7.8e-50
CCDS75137.1 UGT2B4 gene_id:7363|Hs108|chr4 ( 369) 784 191.9 1.1e-48
CCDS82930.1 UGT2B7 gene_id:7364|Hs108|chr4 ( 369) 720 177.0 3.4e-44
CCDS56330.1 UGT2B28 gene_id:54490|Hs108|chr4 ( 335) 618 153.2 4.5e-37
CCDS54841.1 UGT3A1 gene_id:133688|Hs108|chr5 ( 252) 270 72.0 9.2e-13
>>CCDS33405.1 UGT1A4 gene_id:54657|Hs108|chr2 (534 aa)
initn: 3596 init1: 3596 opt: 3596 Z-score: 4528.4 bits: 847.6 E(32554): 0
Smith-Waterman score: 3596; 100.0% identity (100.0% similar) in 534 aa overlap (1-534:1-534)
10 20 30 40 50 60
pF1KE6 MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 SLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 DFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 REVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 REVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
430 440 450 460 470 480
490 500 510 520 530
pF1KE6 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
490 500 510 520 530
>>CCDS2509.1 UGT1A3 gene_id:54659|Hs108|chr2 (534 aa)
initn: 3359 init1: 3359 opt: 3359 Z-score: 4229.8 bits: 792.3 E(32554): 0
Smith-Waterman score: 3359; 93.3% identity (97.4% similar) in 534 aa overlap (1-534:1-534)
10 20 30 40 50 60
pF1KE6 MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVV
:: ::::::: :::::::::::::::::::::::: ::: ::::::.:::::::::::::
CCDS25 MATGLQVPLPWLATGLLLLLSVQPWAESGKVLVVPIDGSHWLSMREVLRELHARGHQAVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNV
::::::::::::.:::::.::. ::: :::: .::.:: .:::::.::.. ::::..::.
CCDS25 LTPEVNMHIKEENFFTLTTYAISWTQDEFDRHVLGHTQLYFETEHFLKKFFRSMAMLNNM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDL
::. :: ::::::::::::::::::::::::::::::.::::::::::.::: : :::::
CCDS25 SLVYHRSCVELLHNEALIRHLNATSFDVVLTDPVNLCAAVLAKYLSIPTVFFLRNIPCDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQ
:::::::::::::::.:::::::::::.:::::::::::::::::.::::::::::::::
CCDS25 DFKGTQCPNPSSYIPRLLTTNSDHMTFMQRVKNMLYPLALSYICHAFSAPYASLASELFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 REVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
:::::::..:.:::::::::::::::::::::::::::::::: ::::::::::::::::
CCDS25 REVSVVDILSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANRKPLSQEFEAYINASGE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
430 440 450 460 470 480
490 500 510 520 530
pF1KE6 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
490 500 510 520 530
>>CCDS33404.1 UGT1A5 gene_id:54579|Hs108|chr2 (534 aa)
initn: 3357 init1: 3357 opt: 3357 Z-score: 4227.2 bits: 791.9 E(32554): 0
Smith-Waterman score: 3357; 93.4% identity (97.4% similar) in 534 aa overlap (1-534:1-534)
10 20 30 40 50 60
pF1KE6 MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVV
:: :::::::.:::::::::::::::::::::::::::: :::::::::.:::::::.::
CCDS33 MATGLQVPLPQLATGLLLLLSVQPWAESGKVLVVPTDGSHWLSMREALRDLHARGHQVVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNV
:: ::::.::::.:::::.::. ::: ::::. ::.::.:::::::: ..:: ::::::.
CCDS33 LTLEVNMYIKEENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLMKFSRRMAIMNNM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDL
:: .:: ::::::::::::::.::::::::::: .::.:::::::::::::: : :::::
CCDS33 SLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQ
:::::::::::::::.::::::::::::::::::::::::::.::. :::::::::::::
CCDS33 DFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 REVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 REVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
430 440 450 460 470 480
490 500 510 520 530
pF1KE6 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
490 500 510 520 530
>>CCDS2510.1 UGT1A1 gene_id:54658|Hs108|chr2 (533 aa)
initn: 2605 init1: 2605 opt: 2605 Z-score: 3279.6 bits: 616.5 E(32554): 2.4e-176
Smith-Waterman score: 2605; 73.0% identity (88.5% similar) in 523 aa overlap (12-534:11-533)
10 20 30 40 50 60
pF1KE6 MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVV
:. :::: . ...::.:..:.::: :::: :...:. :::. ::
CCDS25 MAVESQGGRPLVLGLLLCVLGPVVSHAGKILLIPVDGSHWLSMLGAIQQLQQRGHEIVV
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 LTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNV
:.:.....:.. :.:: .: ::. ... . .. .. ::.. .:.: ... ...
CCDS25 LAPDASLYIRDGAFYTLKTYPVPFQREDVKESFVSLGHNVFENDSFLQRVIKTYKKIKKD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 SLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDL
: : : .::::. :. : .::::.:::: :. ..:.:::.:.::: . .::.:
CCDS25 SAMLLSGCSHLLHNKELMASLAESSFDVMLTDPFLPCSPIVAQYLSLPTVFFLHALPCSL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 DFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQ
.:..:::::: ::.:. :...:::::::::::::: .. ...: . .:::.::::..:
CCDS25 EFEATQCPNPFSYVPRPLSSHSDHMTFLQRVKNMLIAFSQNFLCDVVYSPYATLASEFLQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 REVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
:::.: ::.: :::::::.::: ::::::::::::.::::: . .:::::::::::::::
CCDS25 REVTVQDLLSSASVWLFRSDFVKDYPRPIMPNMVFVGGINCLHQNPLSQEFEAYINASGE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE6 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE6 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE6 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
420 430 440 450 460 470
490 500 510 520 530
pF1KE6 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>CCDS2505.1 UGT1A9 gene_id:54600|Hs108|chr2 (530 aa)
initn: 2386 init1: 2209 opt: 2402 Z-score: 3023.8 bits: 569.2 E(32554): 4.2e-162
Smith-Waterman score: 2402; 68.2% identity (83.8% similar) in 531 aa overlap (4-534:5-530)
10 20 30 40 50
pF1KE6 MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAV
: ::: : . ::: . .::.::.:::: ::: :..:: ....: :::..:
CCDS25 MACTGWTSPLP-LCVCLLLTCG---FAEAGKLLVVPMDGSHWFTMRSVVEKLILRGHEVV
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 VLTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNN
:. :::. .. . :. .:.. .: ...:: ..... .... . . :: :. .:.
CCDS25 VVMPEVSWQLGRSLNCTVKTYSTSYTLEDLDREFKAFAHAQWKAQ-VRSIYSLLMGSYND
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 VSLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCD
. . : :.... :...:. .:::.:. :: . :: ..:::.:.:.: : : : :
CCDS25 IFDLFFSNCRSLFKDKKLVEYLKESSFDAVFLDPFDNCGLIVAKYFSLPSVVFARGILCH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 LDFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELF
.:.::: : ::.:..: :: ::: .::.: .. : .:: : .:::..
CCDS25 YLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLLCHRFFKNALEIASEIL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 QREVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASG
: :. :: :..:.::.: :::.:::.:.::::.::::::: .:::: .::::::::::
CCDS25 QTPVTEYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>CCDS33402.1 UGT1A8 gene_id:54576|Hs108|chr2 (530 aa)
initn: 2386 init1: 2213 opt: 2396 Z-score: 3016.3 bits: 567.8 E(32554): 1.1e-161
Smith-Waterman score: 2396; 67.5% identity (83.9% similar) in 535 aa overlap (1-534:1-530)
10 20 30 40 50
pF1KE6 MAR-GLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAV
::: : :.: : ..::: . .::.::.:::: ::: :..:. ....: :::..:
CCDS33 MARTGWTSPIP-LCVSLLLTCG---FAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVV
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 VLTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNN
:. :::. .. . :. .:.. .: ...:: . .... .... . . .: .. :.
CCDS33 VVMPEVSWQLGKSLNCTVKTYSTSYTLEDLDREFMDFADAQWKAQ-VRSLFSLFLSSSNG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 VSLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCD
. : :.... :...:. .:::.:. :: . :: ..:::.:.:.: : : : :
CCDS33 FFNLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDACGLIVAKYFSLPSVVFARGIACH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 LDFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELF
.:.::: : ::.:..: :: ::: .::.: .. : .:. :: .:::..
CCDS33 YLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLFCQYFSKNALEIASEIL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 QREVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASG
: :.. :: :..:.::.: :::.:::.:.::::.::::::: .:::: .::::::::::
CCDS33 QTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>CCDS2507.1 UGT1A6 gene_id:54578|Hs108|chr2 (532 aa)
initn: 2363 init1: 2363 opt: 2379 Z-score: 2994.8 bits: 563.8 E(32554): 1.7e-160
Smith-Waterman score: 2379; 68.2% identity (84.2% similar) in 525 aa overlap (11-534:10-532)
10 20 30 40 50 60
pF1KE6 MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVV
:...:...: .. . . :.:::: ::: ::::.. .. : :::. ::
CCDS25 MACLLRSFQRISAGVFFL-ALWGMVVGDKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVV
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 LTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNV
..::::. .:: :..: : ::. :.:. .. .. : . .: .. : .
CCDS25 VVPEVNLLLKESKYYTRKIYPVPYDQEELKNRYQSFGNNHFAERSFLTA-PQTEYRNNMI
60 70 80 90 100 110
130 140 150 160 170
pF1KE6 SLALHRC-CVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCD
..:. : ::... . .. ..::...:::. ::..::.::..:.:...: .::.
CCDS25 VIGLYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPCS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 LDFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELF
:. .. :.: ::::. : :::::: ::: :.: : :. . . . : ::: ..
CCDS25 LEHTFSRSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELASAVL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 QREVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASG
.:.:... : . .::::.: :::..::::.:::::::::::: . : :::::::::::::
CCDS25 KRDVDIITLYQKVSVWLLRYDFVLEYPRPVMPNMVFIGGINCKKRKDLSQEFEAYINASG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>CCDS2506.1 UGT1A7 gene_id:54577|Hs108|chr2 (530 aa)
initn: 2342 init1: 2181 opt: 2343 Z-score: 2949.5 bits: 555.4 E(32554): 5.8e-158
Smith-Waterman score: 2343; 66.9% identity (82.4% similar) in 534 aa overlap (1-534:1-530)
10 20 30 40 50 60
pF1KE6 MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVV
:::. . : : . ::: . .:..::.:::: ::: :..:. ....: :::..::
CCDS25 MARAGWTGLLPLYVCLLLTCG---FAKAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVVV
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 LTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNV
. :::. .. . :. .:.. .: .. :: . .... . : : . .: . :..
CCDS25 VMPEVSWQLGRSLNCTVKTYSTSYTLEDQDREFMVFADARW-TAPLRSAFSLLTSSSNGI
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 SLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDL
. : :.... :...:. . ::.:. :: . :: ..:::.:.:.: : : : :
CCDS25 FDLFFSNCRSLFNDRKLVEYLKESCFDAVFLDPFDACGLIVAKYFSLPSVVFARGIFCHY
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 DFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQ
.:.::: : ::.:.:: :: ::: .:: : .. : .: : .:::..:
CCDS25 LEEGAQCPAPLSYVPRLLLGFSDAMTFKERVWNHIMHLEEHLFCPYFFKNVLEIASEILQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 REVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
:.. :: :..:.::.: :::..::.:.::::.::::::: .:::. .:::::::::::
CCDS25 TPVTAYDLYSHTSIWLLRTDFVLEYPKPVMPNMIFIGGINCHQGKPVPMEFEAYINASGE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE6 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE6 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE6 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
420 430 440 450 460 470
490 500 510 520 530
pF1KE6 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>CCDS33403.1 UGT1A10 gene_id:54575|Hs108|chr2 (530 aa)
initn: 2339 init1: 2176 opt: 2339 Z-score: 2944.4 bits: 554.5 E(32554): 1.1e-157
Smith-Waterman score: 2339; 66.9% identity (82.8% similar) in 535 aa overlap (1-534:1-530)
10 20 30 40 50
pF1KE6 MAR-GLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAV
::: : :.: : . ::: . .::.::.:::: ::: :..:. ....: :::..:
CCDS33 MARAGWTSPVP-LCVCLLLTCG---FAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVV
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 VLTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNN
:. :::. .... :. .:.. .: .. .: . .... .... . .: :. ..
CCDS33 VVMPEVSWQLERSLNCTVKTYSTSYTLEDQNREFMVFAHAQWKAQAQ-SIFSLLMSSSSG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 VSLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCD
. : :.... :...:. .:::.:. :: . :: ..:::.:.:.: : : : :
CCDS33 FLDLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDTCGLIVAKYFSLPSVVFTRGIFCH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 LDFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELF
.:.::: : ::.:. : :: ::: .:: : . : .:. . .:::..
CCDS33 HLEEGAQCPAPLSYVPNDLLGFSDAMTFKERVWNHIVHLEDHLFCQYLFRNALEIASEIL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 QREVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASG
: :.. :: :..:.::.: :::.:::.:.::::.::::::: .:::: .::::::::::
CCDS33 QTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>CCDS2508.1 UGT1A6 gene_id:54578|Hs108|chr2 (265 aa)
initn: 1751 init1: 1751 opt: 1751 Z-score: 2208.5 bits: 417.3 E(32554): 1.1e-116
Smith-Waterman score: 1751; 98.5% identity (98.9% similar) in 265 aa overlap (270-534:1-265)
240 250 260 270 280 290
pF1KE6 QREVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASG
:::::::::::: . : :::::::::::::
CCDS25 MPNMVFIGGINCKKRKDLSQEFEAYINASG
10 20 30
300 310 320 330 340 350
pF1KE6 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
40 50 60 70 80 90
360 370 380 390 400 410
pF1KE6 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
100 110 120 130 140 150
420 430 440 450 460 470
pF1KE6 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
160 170 180 190 200 210
480 490 500 510 520 530
pF1KE6 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS25 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
220 230 240 250 260
534 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:11:53 2016 done: Tue Nov 8 16:11:54 2016
Total Scan time: 2.310 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]