Result of FASTA (omim) for
pFN21AE6445
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6445, 521 aa
1>>>pF1KE6445 521 - 521 aa - 521 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4533+/-0.000383; mu= 18.5155+/- 0.024
mean_var=81.7810+/-16.563, 0's: 0 Z-trim(113.1): 12 B-trim: 0 in 0/51
Lambda= 0.141823
statistics sampled from 22286 (22298) to 22286 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.261), width: 16
Scan time: 7.270
The best scores are: opt bits E(85289)
NP_115970 (OMIM: 610531,610532) hyccin [Homo sapie ( 521) 3412 708.2 1.5e-203
XP_011513891 (OMIM: 610531,610532) PREDICTED: hycc ( 521) 3412 708.2 1.5e-203
XP_011513892 (OMIM: 610531,610532) PREDICTED: hycc ( 370) 2198 459.7 7e-129
XP_005249952 (OMIM: 610531,610532) PREDICTED: hycc ( 406) 2187 457.4 3.6e-128
XP_005249951 (OMIM: 610531,610532) PREDICTED: hycc ( 419) 2187 457.5 3.6e-128
>>NP_115970 (OMIM: 610531,610532) hyccin [Homo sapiens] (521 aa)
initn: 3412 init1: 3412 opt: 3412 Z-score: 3775.2 bits: 708.2 E(85289): 1.5e-203
Smith-Waterman score: 3412; 100.0% identity (100.0% similar) in 521 aa overlap (1-521:1-521)
10 20 30 40 50 60
pF1KE6 MFTSEKGVVEEWLSEFKTLPETSLPNYATNLKDKSSLVSSLYKVIQEPQSELLEPVCHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 MFTSEKGVVEEWLSEFKTLPETSLPNYATNLKDKSSLVSSLYKVIQEPQSELLEPVCHQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FEFYRSGEEQLLQFTLQFLPELIWCYLAVSASRNVHSSGCIEALLLGVYNLEIVDKQGHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 FEFYRSGEEQLLQFTLQFLPELIWCYLAVSASRNVHSSGCIEALLLGVYNLEIVDKQGHT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 KVLSFTIPSLSKPSVYHEPSSIGSMALTESALSQHGLSKVVYSGPHPQREMLTAQNRFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 KVLSFTIPSLSKPSVYHEPSSIGSMALTESALSQHGLSKVVYSGPHPQREMLTAQNRFEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LTFLLLCYNAALTYMPSVSLQSLCQICSRICVCGYPRQHVRKYKGISSRIPVSSGFMVQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LTFLLLCYNAALTYMPSVSLQSLCQICSRICVCGYPRQHVRKYKGISSRIPVSSGFMVQM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 LTGIYFAFYNGEWDLAQKALDDIIYRAQLELYPEPLLVANAIKASLPHGPMKSNKEGTRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LTGIYFAFYNGEWDLAQKALDDIIYRAQLELYPEPLLVANAIKASLPHGPMKSNKEGTRC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 IQVEITPTSSRISRNAVTSMSIRGHRWKRHGNTELTGQEELMEISEVDEGFYSRAASSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 IQVEITPTSSRISRNAVTSMSIRGHRWKRHGNTELTGQEELMEISEVDEGFYSRAASSTS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 QSGLSNSSHNCSNKPSIGKNHRRSGGSKTGGKEKETTGESCKDHFARKQTQRAQSENLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 QSGLSNSSHNCSNKPSIGKNHRRSGGSKTGGKEKETTGESCKDHFARKQTQRAQSENLEL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 LSLKRLTLTTSQSLPKPSSHGLAKTAATVFSKSFEQVSGVTVPHNPSSAVGCGAGTDANR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 LSLKRLTLTTSQSLPKPSSHGLAKTAATVFSKSFEQVSGVTVPHNPSSAVGCGAGTDANR
430 440 450 460 470 480
490 500 510 520
pF1KE6 FSACSLQEEKLIYVSERTELPMKHQSGQQRPPSISITLSTD
:::::::::::::::::::::::::::::::::::::::::
NP_115 FSACSLQEEKLIYVSERTELPMKHQSGQQRPPSISITLSTD
490 500 510 520
>>XP_011513891 (OMIM: 610531,610532) PREDICTED: hyccin i (521 aa)
initn: 3412 init1: 3412 opt: 3412 Z-score: 3775.2 bits: 708.2 E(85289): 1.5e-203
Smith-Waterman score: 3412; 100.0% identity (100.0% similar) in 521 aa overlap (1-521:1-521)
10 20 30 40 50 60
pF1KE6 MFTSEKGVVEEWLSEFKTLPETSLPNYATNLKDKSSLVSSLYKVIQEPQSELLEPVCHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFTSEKGVVEEWLSEFKTLPETSLPNYATNLKDKSSLVSSLYKVIQEPQSELLEPVCHQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FEFYRSGEEQLLQFTLQFLPELIWCYLAVSASRNVHSSGCIEALLLGVYNLEIVDKQGHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEFYRSGEEQLLQFTLQFLPELIWCYLAVSASRNVHSSGCIEALLLGVYNLEIVDKQGHT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 KVLSFTIPSLSKPSVYHEPSSIGSMALTESALSQHGLSKVVYSGPHPQREMLTAQNRFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVLSFTIPSLSKPSVYHEPSSIGSMALTESALSQHGLSKVVYSGPHPQREMLTAQNRFEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LTFLLLCYNAALTYMPSVSLQSLCQICSRICVCGYPRQHVRKYKGISSRIPVSSGFMVQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTFLLLCYNAALTYMPSVSLQSLCQICSRICVCGYPRQHVRKYKGISSRIPVSSGFMVQM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 LTGIYFAFYNGEWDLAQKALDDIIYRAQLELYPEPLLVANAIKASLPHGPMKSNKEGTRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTGIYFAFYNGEWDLAQKALDDIIYRAQLELYPEPLLVANAIKASLPHGPMKSNKEGTRC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 IQVEITPTSSRISRNAVTSMSIRGHRWKRHGNTELTGQEELMEISEVDEGFYSRAASSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQVEITPTSSRISRNAVTSMSIRGHRWKRHGNTELTGQEELMEISEVDEGFYSRAASSTS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 QSGLSNSSHNCSNKPSIGKNHRRSGGSKTGGKEKETTGESCKDHFARKQTQRAQSENLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSGLSNSSHNCSNKPSIGKNHRRSGGSKTGGKEKETTGESCKDHFARKQTQRAQSENLEL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 LSLKRLTLTTSQSLPKPSSHGLAKTAATVFSKSFEQVSGVTVPHNPSSAVGCGAGTDANR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSLKRLTLTTSQSLPKPSSHGLAKTAATVFSKSFEQVSGVTVPHNPSSAVGCGAGTDANR
430 440 450 460 470 480
490 500 510 520
pF1KE6 FSACSLQEEKLIYVSERTELPMKHQSGQQRPPSISITLSTD
:::::::::::::::::::::::::::::::::::::::::
XP_011 FSACSLQEEKLIYVSERTELPMKHQSGQQRPPSISITLSTD
490 500 510 520
>>XP_011513892 (OMIM: 610531,610532) PREDICTED: hyccin i (370 aa)
initn: 2226 init1: 2196 opt: 2198 Z-score: 2434.9 bits: 459.7 E(85289): 7e-129
Smith-Waterman score: 2198; 98.2% identity (99.4% similar) in 338 aa overlap (1-338:1-338)
10 20 30 40 50 60
pF1KE6 MFTSEKGVVEEWLSEFKTLPETSLPNYATNLKDKSSLVSSLYKVIQEPQSELLEPVCHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFTSEKGVVEEWLSEFKTLPETSLPNYATNLKDKSSLVSSLYKVIQEPQSELLEPVCHQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FEFYRSGEEQLLQFTLQFLPELIWCYLAVSASRNVHSSGCIEALLLGVYNLEIVDKQGHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FEFYRSGEEQLLQFTLQFLPELIWCYLAVSASRNVHSSGCIEALLLGVYNLEIVDKQGHT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 KVLSFTIPSLSKPSVYHEPSSIGSMALTESALSQHGLSKVVYSGPHPQREMLTAQNRFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVLSFTIPSLSKPSVYHEPSSIGSMALTESALSQHGLSKVVYSGPHPQREMLTAQNRFEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LTFLLLCYNAALTYMPSVSLQSLCQICSRICVCGYPRQHVRKYKGISSRIPVSSGFMVQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTFLLLCYNAALTYMPSVSLQSLCQICSRICVCGYPRQHVRKYKGISSRIPVSSGFMVQM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 LTGIYFAFYNGEWDLAQKALDDIIYRAQLELYPEPLLVANAIKASLPHGPMKSNKEGTRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTGIYFAFYNGEWDLAQKALDDIIYRAQLELYPEPLLVANAIKASLPHGPMKSNKEGTRC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 IQVEITPTSSRISRNAVTSMSIRGHRWKRHGNTELTGQEELMEISEVDEGFYSRAASSTS
:::::::::::::::::::::::::::::::... . :
XP_011 IQVEITPTSSRISRNAVTSMSIRGHRWKRHGGSKGSRQNSTSNDVDSVSCWNLQSLFKYD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 QSGLSNSSHNCSNKPSIGKNHRRSGGSKTGGKEKETTGESCKDHFARKQTQRAQSENLEL
XP_011 LNCQKIVFKI
370
>>XP_005249952 (OMIM: 610531,610532) PREDICTED: hyccin i (406 aa)
initn: 2185 init1: 2185 opt: 2187 Z-score: 2422.1 bits: 457.4 E(85289): 3.6e-128
Smith-Waterman score: 2187; 92.0% identity (95.3% similar) in 363 aa overlap (1-363:1-363)
10 20 30 40 50 60
pF1KE6 MFTSEKGVVEEWLSEFKTLPETSLPNYATNLKDKSSLVSSLYKVIQEPQSELLEPVCHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MFTSEKGVVEEWLSEFKTLPETSLPNYATNLKDKSSLVSSLYKVIQEPQSELLEPVCHQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FEFYRSGEEQLLQFTLQFLPELIWCYLAVSASRNVHSSGCIEALLLGVYNLEIVDKQGHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FEFYRSGEEQLLQFTLQFLPELIWCYLAVSASRNVHSSGCIEALLLGVYNLEIVDKQGHT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 KVLSFTIPSLSKPSVYHEPSSIGSMALTESALSQHGLSKVVYSGPHPQREMLTAQNRFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVLSFTIPSLSKPSVYHEPSSIGSMALTESALSQHGLSKVVYSGPHPQREMLTAQNRFEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LTFLLLCYNAALTYMPSVSLQSLCQICSRICVCGYPRQHVRKYKGISSRIPVSSGFMVQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTFLLLCYNAALTYMPSVSLQSLCQICSRICVCGYPRQHVRKYKGISSRIPVSSGFMVQM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 LTGIYFAFYNGEWDLAQKALDDIIYRAQLELYPEPLLVANAIKASLPHGPMKSNKEGTRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTGIYFAFYNGEWDLAQKALDDIIYRAQLELYPEPLLVANAIKASLPHGPMKSNKEGTRC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 IQVEITPTSSRISRNAVTSMSIRGHRWKRHGNTELTGQEELMEISEVDEGFYSRAASSTS
:::::::::::::::::::::::::::::: . . ... . : . : . .:. .
XP_005 IQVEITPTSSRISRNAVTSMSIRGHRWKRHEQPDNNNDATELGILVIPEISVTNVAGERT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 QSGLSNSSHNCSNKPSIGKNHRRSGGSKTGGKEKETTGESCKDHFARKQTQRAQSENLEL
.:
XP_005 GNGEKGRTLGEIDAQHIQGVQETATDPRTESKGLPEIRRQKSEIQN
370 380 390 400
>>XP_005249951 (OMIM: 610531,610532) PREDICTED: hyccin i (419 aa)
initn: 2185 init1: 2185 opt: 2187 Z-score: 2421.9 bits: 457.5 E(85289): 3.6e-128
Smith-Waterman score: 2187; 92.0% identity (95.3% similar) in 363 aa overlap (1-363:1-363)
10 20 30 40 50 60
pF1KE6 MFTSEKGVVEEWLSEFKTLPETSLPNYATNLKDKSSLVSSLYKVIQEPQSELLEPVCHQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MFTSEKGVVEEWLSEFKTLPETSLPNYATNLKDKSSLVSSLYKVIQEPQSELLEPVCHQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FEFYRSGEEQLLQFTLQFLPELIWCYLAVSASRNVHSSGCIEALLLGVYNLEIVDKQGHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FEFYRSGEEQLLQFTLQFLPELIWCYLAVSASRNVHSSGCIEALLLGVYNLEIVDKQGHT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 KVLSFTIPSLSKPSVYHEPSSIGSMALTESALSQHGLSKVVYSGPHPQREMLTAQNRFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVLSFTIPSLSKPSVYHEPSSIGSMALTESALSQHGLSKVVYSGPHPQREMLTAQNRFEV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LTFLLLCYNAALTYMPSVSLQSLCQICSRICVCGYPRQHVRKYKGISSRIPVSSGFMVQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTFLLLCYNAALTYMPSVSLQSLCQICSRICVCGYPRQHVRKYKGISSRIPVSSGFMVQM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 LTGIYFAFYNGEWDLAQKALDDIIYRAQLELYPEPLLVANAIKASLPHGPMKSNKEGTRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTGIYFAFYNGEWDLAQKALDDIIYRAQLELYPEPLLVANAIKASLPHGPMKSNKEGTRC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 IQVEITPTSSRISRNAVTSMSIRGHRWKRHGNTELTGQEELMEISEVDEGFYSRAASSTS
:::::::::::::::::::::::::::::: . . ... . : . : . .:. .
XP_005 IQVEITPTSSRISRNAVTSMSIRGHRWKRHEQPDNNNDATELGILVIPEISVTNVAGERT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 QSGLSNSSHNCSNKPSIGKNHRRSGGSKTGGKEKETTGESCKDHFARKQTQRAQSENLEL
.:
XP_005 GNGEKGRTLGEIDAQHIQGVQETATDPRTESKGLPEIRRQKSVRKMMEDGINSPGRVQF
370 380 390 400 410
521 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:22:31 2016 done: Tue Nov 8 13:22:32 2016
Total Scan time: 7.270 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]