Result of FASTA (ccds) for
pFN21AE5745
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5745, 640 aa
1>>>pF1KE5745 640 - 640 aa - 640 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6735+/-0.000926; mu= 8.8533+/- 0.055
mean_var=140.2877+/-27.948, 0's: 0 Z-trim(110.3): 47 B-trim: 655 in 2/49
Lambda= 0.108284
statistics sampled from 11478 (11519) to 11478 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.354), width: 16
Scan time: 3.980
The best scores are: opt bits E(32554)
CCDS4861.1 USP49 gene_id:25862|Hs108|chr6 ( 640) 4375 695.3 6.5e-200
CCDS69111.1 USP49 gene_id:25862|Hs108|chr6 ( 688) 4274 679.6 3.9e-195
CCDS9053.1 USP44 gene_id:84101|Hs108|chr12 ( 712) 1796 292.4 1.4e-78
CCDS58370.1 USP3 gene_id:9960|Hs108|chr15 ( 476) 535 95.4 2e-19
>>CCDS4861.1 USP49 gene_id:25862|Hs108|chr6 (640 aa)
initn: 4375 init1: 4375 opt: 4375 Z-score: 3702.5 bits: 695.3 E(32554): 6.5e-200
Smith-Waterman score: 4375; 100.0% identity (100.0% similar) in 640 aa overlap (1-640:1-640)
10 20 30 40 50 60
pF1KE5 MDRCKHVGRLRLAQDHSILNPQKWCCLECATTESVWACLKCSHVACGRYIEDHALKHFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 MDRCKHVGRLRLAQDHSILNPQKWCCLECATTESVWACLKCSHVACGRYIEDHALKHFEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TGHPLAMEVRDLYVFCYLCKDYVLNDNPEGDLKLLRSSLLAVRGQKQDTPVRRGRTLRSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 TGHPLAMEVRDLYVFCYLCKDYVLNDNPEGDLKLLRSSLLAVRGQKQDTPVRRGRTLRSM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ASGEDVVLPQRAPQGQPQMLTALWYRRQRLLARTLRLWFEKSSRGQAKLEQRRQEEALER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 ASGEDVVLPQRAPQGQPQMLTALWYRRQRLLARTLRLWFEKSSRGQAKLEQRRQEEALER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 KKEEARRRRREVKRRLLEELASTPPRKSARLLLHTPRDAGPAASRPAALPTSRRVPAATL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 KKEEARRRRREVKRRLLEELASTPPRKSARLLLHTPRDAGPAASRPAALPTSRRVPAATL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 KLRRQPAMAPGVTGLRNLGNTCYMNSILQVLSHLQKFRECFLNLDPSKTEHLFPKATNGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 KLRRQPAMAPGVTGLRNLGNTCYMNSILQVLSHLQKFRECFLNLDPSKTEHLFPKATNGK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 TQLSGKPTNSSATELSLRNDRAEACEREGFCWNGRASISRSLELIQNKEPSSKHISLCRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 TQLSGKPTNSSATELSLRNDRAEACEREGFCWNGRASISRSLELIQNKEPSSKHISLCRE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 LHTLFRVMWSGKWALVSPFAMLHSVWSLIPAFRGYDQQDAQEFLCELLHKVQQELESEGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 LHTLFRVMWSGKWALVSPFAMLHSVWSLIPAFRGYDQQDAQEFLCELLHKVQQELESEGT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 TRRILIPFSQRKLTKQVLKVVNTIFHGQLLSQVTCISCNYKSNTIEPFWDLSLEFPERYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 TRRILIPFSQRKLTKQVLKVVNTIFHGQLLSQVTCISCNYKSNTIEPFWDLSLEFPERYH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 CIEKGFVPLNQTECLLTEMLAKFTETEALEGRIYACDQCNSKRRKSNPKPLVLSEARKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 CIEKGFVPLNQTECLLTEMLAKFTETEALEGRIYACDQCNSKRRKSNPKPLVLSEARKQL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 MIYRLPQVLRLHLKRFRWSGRNHREKIGVHVVFDQVLTMEPYCCRDMLSSLDKETFAYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 MIYRLPQVLRLHLKRFRWSGRNHREKIGVHVVFDQVLTMEPYCCRDMLSSLDKETFAYDL
550 560 570 580 590 600
610 620 630 640
pF1KE5 SAVVMHHGKGFGSGHYTAYCYNTEGGACALLCGVGDTERG
::::::::::::::::::::::::::::::::::::::::
CCDS48 SAVVMHHGKGFGSGHYTAYCYNTEGGACALLCGVGDTERG
610 620 630 640
>>CCDS69111.1 USP49 gene_id:25862|Hs108|chr6 (688 aa)
initn: 4274 init1: 4274 opt: 4274 Z-score: 3616.8 bits: 679.6 E(32554): 3.9e-195
Smith-Waterman score: 4274; 100.0% identity (100.0% similar) in 626 aa overlap (1-626:1-626)
10 20 30 40 50 60
pF1KE5 MDRCKHVGRLRLAQDHSILNPQKWCCLECATTESVWACLKCSHVACGRYIEDHALKHFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 MDRCKHVGRLRLAQDHSILNPQKWCCLECATTESVWACLKCSHVACGRYIEDHALKHFEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 TGHPLAMEVRDLYVFCYLCKDYVLNDNPEGDLKLLRSSLLAVRGQKQDTPVRRGRTLRSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 TGHPLAMEVRDLYVFCYLCKDYVLNDNPEGDLKLLRSSLLAVRGQKQDTPVRRGRTLRSM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 ASGEDVVLPQRAPQGQPQMLTALWYRRQRLLARTLRLWFEKSSRGQAKLEQRRQEEALER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 ASGEDVVLPQRAPQGQPQMLTALWYRRQRLLARTLRLWFEKSSRGQAKLEQRRQEEALER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 KKEEARRRRREVKRRLLEELASTPPRKSARLLLHTPRDAGPAASRPAALPTSRRVPAATL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 KKEEARRRRREVKRRLLEELASTPPRKSARLLLHTPRDAGPAASRPAALPTSRRVPAATL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 KLRRQPAMAPGVTGLRNLGNTCYMNSILQVLSHLQKFRECFLNLDPSKTEHLFPKATNGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 KLRRQPAMAPGVTGLRNLGNTCYMNSILQVLSHLQKFRECFLNLDPSKTEHLFPKATNGK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 TQLSGKPTNSSATELSLRNDRAEACEREGFCWNGRASISRSLELIQNKEPSSKHISLCRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 TQLSGKPTNSSATELSLRNDRAEACEREGFCWNGRASISRSLELIQNKEPSSKHISLCRE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 LHTLFRVMWSGKWALVSPFAMLHSVWSLIPAFRGYDQQDAQEFLCELLHKVQQELESEGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 LHTLFRVMWSGKWALVSPFAMLHSVWSLIPAFRGYDQQDAQEFLCELLHKVQQELESEGT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 TRRILIPFSQRKLTKQVLKVVNTIFHGQLLSQVTCISCNYKSNTIEPFWDLSLEFPERYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 TRRILIPFSQRKLTKQVLKVVNTIFHGQLLSQVTCISCNYKSNTIEPFWDLSLEFPERYH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE5 CIEKGFVPLNQTECLLTEMLAKFTETEALEGRIYACDQCNSKRRKSNPKPLVLSEARKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 CIEKGFVPLNQTECLLTEMLAKFTETEALEGRIYACDQCNSKRRKSNPKPLVLSEARKQL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE5 MIYRLPQVLRLHLKRFRWSGRNHREKIGVHVVFDQVLTMEPYCCRDMLSSLDKETFAYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS69 MIYRLPQVLRLHLKRFRWSGRNHREKIGVHVVFDQVLTMEPYCCRDMLSSLDKETFAYDL
550 560 570 580 590 600
610 620 630 640
pF1KE5 SAVVMHHGKGFGSGHYTAYCYNTEGGACALLCGVGDTERG
::::::::::::::::::::::::::
CCDS69 SAVVMHHGKGFGSGHYTAYCYNTEGGFWVHCNDSKLNVCSVEEVCKTQAYILFYTQRTVQ
610 620 630 640 650 660
>>CCDS9053.1 USP44 gene_id:84101|Hs108|chr12 (712 aa)
initn: 2554 init1: 803 opt: 1796 Z-score: 1524.4 bits: 292.4 E(32554): 1.4e-78
Smith-Waterman score: 2582; 59.9% identity (79.1% similar) in 654 aa overlap (1-626:4-647)
10 20 30 40 50
pF1KE5 MDRCKHVGRLRLAQDHSILNPQKWCCLECATTESVWACLKCSHVACGRYIEDHALKH
:: :::::.:.:::::: :::::: :..: ::::.::::.:::::::::::.:::::
CCDS90 MLAMDTCKHVGQLQLAQDHSSLNPQKWHCVDCNTTESIWACLSCSHVACGRYIEEHALKH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE5 FEETGHPLAMEVRDLYVFCYLCKDYVLNDNPEGDLKLLRSSLLAVRGQKQDTPVRRGRTL
:.:..::.:.:: ..::::::: ::::::: ::::::: .: :...:. .: :: :
CCDS90 FQESSHPVALEVNEMYVFCYLCDDYVLNDNTTGDLKLLRRTLSAIKSQNYHCTTRSGRFL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE5 RSMASGEDVVL----PQRAPQGQPQMLTALWYRRQRLLARTLRLWFEKSSRGQAKLEQRR
:::..:.: . : :.. :. ::::.::. :... .: :::.: :. : :.
CCDS90 RSMGTGDDSYFLHDGAQSLLQSEDQLYTALWHRRRILMGKIFRTWFEQSPIGRKKQEEPF
130 140 150 160 170 180
180 190 200 210 220
pF1KE5 QEEALERKKEEARRRRREVKRRLLEELASTPPRKSARLL------------LHTPRDAGP
::. . :.:...::.:.. .. :: : ::::: :: ...: ..
CCDS90 QEKIV--VKREVKKRRQELEYQVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPA
190 200 210 220 230
230 240 250 260 270
pF1KE5 AASRPAALPTS-----RRVPAATLKLRRQPAMAPGVTGLRNLGNTCYMNSILQVLSHLQK
. .. .: :: ..: ...: :.: ..:::::::::::::::::.:::::::
CCDS90 SPAKDKVLSTSENEISQKVSDSSVK--RRPIVTPGVTGLRNLGNTCYMNSVLQVLSHLLI
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE5 FRECFLNLDPSKTEHLFPKATNGKTQLSGKP--TNSSATELS--LRNDRAEACEREGFC-
::.:::.:: .. . ... ::. .: :.. . ... ..: . .: :..
CCDS90 FRQCFLKLD---LNQWLAMTASEKTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLS
300 310 320 330 340 350
340 350 360 370 380
pF1KE5 --WNGRASISRSLELIQNKEPSSKHISLCRELHTLFRVMWSGKWALVSPFAMLHSVWSLI
.: :: .:..:::: :::.:..::::.::::::.:::::::::::::::::::: ::
CCDS90 SGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLI
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE5 PAFRGYDQQDAQEFLCELLHKVQQELESEGTTRRILIPFSQRKLTKQVLKVVNTIFHGQL
:::::: :::::::::::: :.:.:::. ::. ::: ::::: ::::.:::.::::::
CCDS90 PAFRGYAQQDAQEFLCELLDKIQRELETTGTSLPALIPTSQRKLIKQVLNVVNNIFHGQL
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE5 LSQVTCISCNYKSNTIEPFWDLSLEFPERYHCIEKGFVPLNQTECLLTEMLAKFTETEAL
::::::..:. :::::::::::::::::::.: : . . ::.:::::::::::::
CCDS90 LSQVTCLACDNKSNTIEPFWDLSLEFPERYQCSGKD---IASQPCLVTEMLAKFTETEAL
480 490 500 510 520 530
510 520 530 540 550 560
pF1KE5 EGRIYACDQCNSKRRKSNPKPLVLSEARKQLMIYRLPQVLRLHLKRFRWSGRNHREKIGV
::.::.:::::::::. . ::.::.::.::::: .::::::::::::::::::.::::::
CCDS90 EGKIYVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGV
540 550 560 570 580 590
570 580 590 600 610 620
pF1KE5 HVVFDQVLTMEPYCCRDMLSSLDKETFAYDLSAVVMHHGKGFGSGHYTAYCYNTEGGACA
:: :...:.:::::::. :.:: : : :::::::::::::::::::::::::.:::
CCDS90 HVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWV
600 610 620 630 640 650
630 640
pF1KE5 LLCGVGDTERG
CCDS90 HCNDSKLSMCTMDEVCKAQAYILFYTQRVTENGHSKLLPPELLLGSQHPNEDADTSSNEI
660 670 680 690 700 710
>>CCDS58370.1 USP3 gene_id:9960|Hs108|chr15 (476 aa)
initn: 713 init1: 175 opt: 535 Z-score: 462.4 bits: 95.4 E(32554): 2e-19
Smith-Waterman score: 583; 32.6% identity (60.2% similar) in 377 aa overlap (253-619:115-431)
230 240 250 260 270 280
pF1KE5 ASRPAALPTSRRVPAATLKLRRQPAMAPGVTGLRNLGNTCYMNSILQVLSHLQKFRECFL
::::::::::.::.::: ::....: :..
CCDS58 DRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQF-CCYF
90 100 110 120 130 140
290 300 310 320 330 340
pF1KE5 NLDPSKTEHLFPKATNGKTQLSGKPTNSSATELSLRNDRAEACEREGFCWNGRASISRSL
. : :.:: ::... :.
CCDS58 KELP-------------------------AVELR----------------NGKTAGRRTY
150 160
350 360 370 380 390 400
pF1KE5 ELIQNKEPSSKHISLCRELHTLFRVMWSGKWALVSPFAMLHSVWSLIPAFRGYDQQDAQE
... .....:: .:.. . ..:.:. . :: .... ::...: ::::.::::.:
CCDS58 ---HTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHE
170 180 190 200 210
410 420 430 440 450
pF1KE5 FLCELLHKVQQELES--EGTTRRILIPF------SQRKLTKQVLKVVNTIFHGQLLSQVT
:. :: ... ::.. .:..: .. :.. . . ::..:: : : ..:.
CCDS58 FMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNEVN
220 230 240 250 260 270
460 470 480 490 500 510
pF1KE5 CISCNYKSNTIEPFWDLSLEFPERYHCIEKGFVPLNQTECLLTEMLAKFTETEAL-EGRI
:. :. .: ..:: ::::..: ... ... : : : . : .::. : : : ..
CCDS58 CLICGTESRKFDPFLDLSLDIPSQFRS-KRSKNQENGPVCSLRDCLRSFTDLEELDETEL
280 290 300 310 320 330
520 530 540 550 560 570
pF1KE5 YACDQCNSKRRKSNPKPLVLSEARKQLMIYRLPQVLRLHLKRFRWSGRNHREKIGVHVVF
: : .:..:.... :.. : .::.:: ::::::.:.. :.:. ..: :
CCDS58 YMCHKCKKKQKST-----------KKFWIQKLPKVLCLHLKRFHWTAY-LRNKVDTYVEF
340 350 360 370 380
580 590 600 610 620 630
pF1KE5 D-QVLTMEPYCCRDMLSSLDKETFAYDLSAVVMHHGKGFGSGHYTAYCYNTEGGACALLC
. : :. : . :. :. :::.:::.:::.: ::::::::
CCDS58 PLRGLDMKCYLLEPENSG--PESCLYDLAAVVVHHGSGVGSGHYTAYATHEGRWFHFNDS
390 400 410 420 430 440
640
pF1KE5 GVGDTERG
CCDS58 TVTLTDEETVVKAKAYILFYVEHQAKAGSDKL
450 460 470
640 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 06:19:01 2016 done: Tue Nov 8 06:19:02 2016
Total Scan time: 3.980 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]