Result of FASTA (ccds) for
pFN21AE5646
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5646, 492 aa
1>>>pF1KE5646 492 - 492 aa - 492 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2423+/-0.00123; mu= 5.2914+/- 0.074
mean_var=233.5669+/-50.309, 0's: 0 Z-trim(109.1): 113 B-trim: 652 in 1/50
Lambda= 0.083921
statistics sampled from 10556 (10666) to 10556 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.676), E-opt: 0.2 (0.328), width: 16
Scan time: 3.130
The best scores are: opt bits E(32554)
CCDS34550.1 PPIL4 gene_id:85313|Hs108|chr6 ( 492) 3319 415.3 7.4e-116
CCDS2333.1 PPIL3 gene_id:53938|Hs108|chr2 ( 161) 461 68.8 5e-12
CCDS3982.2 CWC27 gene_id:10283|Hs108|chr5 ( 472) 446 67.5 3.7e-11
CCDS75252.1 CWC27 gene_id:10283|Hs108|chr5 ( 381) 442 66.9 4.4e-11
>>CCDS34550.1 PPIL4 gene_id:85313|Hs108|chr6 (492 aa)
initn: 3319 init1: 3319 opt: 3319 Z-score: 2193.5 bits: 415.3 E(32554): 7.4e-116
Smith-Waterman score: 3319; 100.0% identity (100.0% similar) in 492 aa overlap (1-492:1-492)
10 20 30 40 50 60
pF1KE5 MAVLLETTLGDVVIDLYTEERPRACLNFLKLCKIKYYNYCLIHNVQRDFIIQTGDPTGTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MAVLLETTLGDVVIDLYTEERPRACLNFLKLCKIKYYNYCLIHNVQRDFIIQTGDPTGTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 RGGESIFGQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNGSDQHGSQFLITTGENLDYLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 RGGESIFGQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNGSDQHGSQFLITTGENLDYLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 GVHTVFGEVTEGMDIIKKINETFVDKDFVPYQDIRINHTVILDDPFDDPPDLLIPDRSPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 GVHTVFGEVTEGMDIIKKINETFVDKDFVPYQDIRINHTVILDDPFDDPPDLLIPDRSPE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE5 PTREQLDSGRIGADEEIDDFKGRSAEEVEEIKAEKEAKTQAILLEMVGDLPDADIKPPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 PTREQLDSGRIGADEEIDDFKGRSAEEVEEIKAEKEAKTQAILLEMVGDLPDADIKPPEN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE5 VLFVCKLNPVTTDEDLEIIFSRFGPIRSCEVIRDWKTGESLCYAFIEFEKEEDCEKAFFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 VLFVCKLNPVTTDEDLEIIFSRFGPIRSCEVIRDWKTGESLCYAFIEFEKEEDCEKAFFK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE5 MDNVLIDDRRIHVDFSQSVAKVKWKGKGGKYTKSDFKEYEKEQDKPPNLVLKDKVKPKQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 MDNVLIDDRRIHVDFSQSVAKVKWKGKGGKYTKSDFKEYEKEQDKPPNLVLKDKVKPKQD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE5 TKYDLILDEQAEDSKSSHSHTSKKHKKKTHHCSEEKEDEDYMPIKNTNQDIYREMGFGHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 TKYDLILDEQAEDSKSSHSHTSKKHKKKTHHCSEEKEDEDYMPIKNTNQDIYREMGFGHY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE5 EEEESCWEKQKSEKRDRTQNRSRSRSRERDGHYSNSHKSKYQTDLYERERSKKRDRSRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS34 EEEESCWEKQKSEKRDRTQNRSRSRSRERDGHYSNSHKSKYQTDLYERERSKKRDRSRSP
430 440 450 460 470 480
490
pF1KE5 KKSKDKEKSKYR
::::::::::::
CCDS34 KKSKDKEKSKYR
490
>>CCDS2333.1 PPIL3 gene_id:53938|Hs108|chr2 (161 aa)
initn: 342 init1: 264 opt: 461 Z-score: 329.5 bits: 68.8 E(32554): 5e-12
Smith-Waterman score: 461; 41.9% identity (72.5% similar) in 167 aa overlap (1-166:1-159)
10 20 30 40 50 60
pF1KE5 MAVLLETTLGDVVIDLYTEERPRACLNFLKLCKIKYYNYCLIHNVQRDFIIQTGDPTGTG
:.: :.: .::. :... :. :..: ::: :: .::: :..: . :..:::::::::
CCDS23 MSVTLHTDVGDIKIEVFCERTPKTCENFLALCASNYYNGCIFHRNIKGFMVQTGDPTGTG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 RGGESIFGQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNGSDQHGSQFLITTGENLDYLD
:::.::.:. . :. : . .::. .:.:::.::: . .::::.:: :.. .::
CCDS23 RGGNSIWGKKFEDEYSEY-------LKHNVRGVVSMANNGPNTNGSQFFITYGKQ-PHLD
70 80 90 100 110
130 140 150 160 170
pF1KE5 GVHTVFGEVTEGMDIIKKINETFVD-KDFVPYQDIRINHTVILDDPFDDPPDLLIPDRSP
.::::.: .:.. . .... :. : . : .:..:. .: .::
CCDS23 MKYTVFGKVIDGLETLDELEKLPVNEKTYRPLNDVHIKDITIHANPFAQ
120 130 140 150 160
180 190 200 210 220 230
pF1KE5 EPTREQLDSGRIGADEEIDDFKGRSAEEVEEIKAEKEAKTQAILLEMVGDLPDADIKPPE
>>CCDS3982.2 CWC27 gene_id:10283|Hs108|chr5 (472 aa)
initn: 459 init1: 266 opt: 446 Z-score: 313.9 bits: 67.5 E(32554): 3.7e-11
Smith-Waterman score: 450; 26.6% identity (55.1% similar) in 497 aa overlap (3-474:15-472)
10 20 30 40
pF1KE5 MAVLLETTLGDVVIDLYTEERPRACLNFLKLCKIKYYNYCLIHNVQRD
:::.:: ::. :.:...: :.:: ::..:: ::. ..: :
CCDS39 MSNIYIQEPPTNGKVLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVPG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 FIIQTGDPTGTGRGGESIFGQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNGSDQHGSQF
::.: ::::::: :::::.: . :. :.. :.. ...: :.:.: :: ..::::
CCDS39 FIVQGGDPTGTGSGGESIYGAPFKDE---FHS----RLRFNRRGLVAMANAGSHDNGSQF
70 80 90 100 110
110 120 130 140 150 160
pF1KE5 LITTGENLDYLDGVHTVFGEVT-EGMDIIKKINETFVDKDFVPYQDIRINHTVILDDPFD
..: :. : :.. ::.::.:: . . . ...:. .: : :.. .:. .: .:::
CCDS39 FFTLGRA-DELNNKHTIFGKVTGDTVYNMLRLSEVDIDDDERPHNPHKIKSCEVLFNPFD
120 130 140 150 160 170
170 180 190 200
pF1KE5 D--P----------PDLLIPDRSPEPTRE--QLDSGRIGADEEID------DFKGRSAEE
: : :. . .:. :.. :. :. . .:: . ..::.:
CCDS39 DIIPREIKRLKKEKPEEEVKKLKPKGTKNFSLLSFGEEAEEEEEEVNRVSQSMKGKSKSS
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE5 VEEIKAEKEAKTQAILLEMVGDLPDADIKPPENVLFVCKLNPVTTDEDLEIIFSRFGPIR
. .: . . .. .. :: :: . :. . : : : . .
CCDS39 HDLLKDDPHLSSVPVVESEKGDAPDL-VDDGED----------ESAEHDEYIDGDEKNLM
240 250 260 270 280
270 280 290 300 310 320
pF1KE5 SCEVIRDWKTGESLCYAFIEFEKEEDCEKAFFKMDNVLIDDRRIHVDFSQSVAKVKWKGK
.. . : : : .. : . :: . .. : . : .... . .: : :
CCDS39 RERIAKKLKKDTS---ANVKSAGEGEVEKKSVSRSEELRKEAR---QLKRELLAAKQK-K
290 300 310 320 330
330 340 350 360 370 380
pF1KE5 GGKYTKSDFKEYEKEQDKPPNLVLKDKVKPKQDTKYDLILDEQAEDSKSSHSHTS---KK
. .:. :. : :.. ::. .. . . :: ::. . .:.. . : ...: ..
CCDS39 VENAAKQAEKRSE-EEEAPPDGAVAEYRREKQ--KYEALRKQQSKKGTSREDQTLALLNQ
340 350 360 370 380 390
390 400 410 420 430 440
pF1KE5 HKKKTHHCSEEKEDEDYMPIKNTNQDIYREMGFGHYEEEESCWEKQKSEKRDRTQNRSRS
:.: . : ..: .: ....: : ..: . : .:... : :. :
CCDS39 FKSKLTQAIAETPEND-IPETEVEDD---EGWMSHVLQFE---DKSRKVKDASMQD---S
400 410 420 430 440
450 460 470 480 490
pF1KE5 RSRE-RDGHYSNSHKSKYQTDLYERERSKKRDRSRSPKKSKDKEKSKYR
. : : . ... . .. ::....:
CCDS39 DTFEIYDPRNPVNKRRREESKKLMREKKERR
450 460 470
>>CCDS75252.1 CWC27 gene_id:10283|Hs108|chr5 (381 aa)
initn: 425 init1: 266 opt: 442 Z-score: 312.4 bits: 66.9 E(32554): 4.4e-11
Smith-Waterman score: 445; 34.3% identity (62.2% similar) in 251 aa overlap (3-232:15-257)
10 20 30 40
pF1KE5 MAVLLETTLGDVVIDLYTEERPRACLNFLKLCKIKYYNYCLIHNVQRD
:::.:: ::. :.:...: :.:: ::..:: ::. ..: :
CCDS75 MSNIYIQEPPTNGKVLLKTTAGDIDIELWSKEAPKACRNFIQLCLEAYYDNTIFHRVVPG
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE5 FIIQTGDPTGTGRGGESIFGQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNGSDQHGSQF
::.: ::::::: :::::.: . :. :.. :.. ...: :.:.: :: ..::::
CCDS75 FIVQGGDPTGTGSGGESIYGAPFKDE---FHS----RLRFNRRGLVAMANAGSHDNGSQF
70 80 90 100 110
110 120 130 140 150 160
pF1KE5 LITTGENLDYLDGVHTVFGEVT-EGMDIIKKINETFVDKDFVPYQDIRINHTVILDDPFD
..: :. : :.. ::.::.:: . . . ...:. .: : :.. .:. .: .:::
CCDS75 FFTLGRA-DELNNKHTIFGKVTGDTVYNMLRLSEVDIDDDERPHNPHKIKSCEVLFNPFD
120 130 140 150 160 170
170 180 190 200
pF1KE5 D--P----------PDLLIPDRSPEPTRE--QLDSGRIGADEEID------DFKGRSAEE
: : :. . .:. :.. :. :. . .:: . ..::.:
CCDS75 DIIPREIKRLKKEKPEEEVKKLKPKGTKNFSLLSFGEEAEEEEEEVNRVSQSMKGKSKSS
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE5 VEEIKAEKEAKTQAILLEMVGDLPDADIKPPENVLFVCKLNPVTTDEDLEIIFSRFGPIR
. .: . . .. .. :: ::
CCDS75 HDLLKDDPHLSSVPVVESEKGDAPDLVDDGEDESAEHDEYIDGDEKNLMRERIAKKLKKD
240 250 260 270 280 290
492 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 05:30:52 2016 done: Tue Nov 8 05:30:53 2016
Total Scan time: 3.130 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]