Result of FASTA (omim) for
pFN21AE5005
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5005, 467 aa
1>>>pF1KE5005 467 - 467 aa - 467 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.0560+/-0.000523; mu= -3.9408+/- 0.032
mean_var=473.8758+/-105.354, 0's: 0 Z-trim(118.3): 232 B-trim: 1850 in 1/56
Lambda= 0.058917
statistics sampled from 30782 (31080) to 30782 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.364), width: 16
Scan time: 8.090
The best scores are: opt bits E(85289)
NP_003983 (OMIM: 602990) dual specificity protein ( 490) 2207 202.7 1.8e-51
XP_016877399 (OMIM: 602990) PREDICTED: dual specif ( 490) 2207 202.7 1.8e-51
XP_016877398 (OMIM: 602990) PREDICTED: dual specif ( 490) 2207 202.7 1.8e-51
NP_001123500 (OMIM: 602990) dual specificity prote ( 638) 2207 202.9 2.1e-51
XP_016877396 (OMIM: 602990) PREDICTED: dual specif ( 655) 2207 202.9 2.2e-51
XP_005254208 (OMIM: 602990) PREDICTED: dual specif ( 652) 2187 201.2 7.1e-51
XP_016877395 (OMIM: 602990) PREDICTED: dual specif ( 669) 2187 201.2 7.2e-51
XP_011519508 (OMIM: 602990) PREDICTED: dual specif ( 642) 1822 170.2 1.5e-41
XP_011519511 (OMIM: 602990) PREDICTED: dual specif ( 659) 1822 170.2 1.6e-41
XP_016877397 (OMIM: 602990) PREDICTED: dual specif ( 508) 1802 168.3 4.3e-41
XP_011519507 (OMIM: 602990) PREDICTED: dual specif ( 656) 1802 168.5 5e-41
XP_016877394 (OMIM: 602990) PREDICTED: dual specif ( 673) 1802 168.5 5.1e-41
XP_011507445 (OMIM: 602989) PREDICTED: dual specif ( 498) 1628 153.5 1.2e-36
NP_001281267 (OMIM: 602989) dual specificity prote ( 499) 1625 153.3 1.4e-36
XP_005244935 (OMIM: 602989) PREDICTED: dual specif ( 497) 1615 152.4 2.6e-36
NP_003984 (OMIM: 602989) dual specificity protein ( 498) 1614 152.3 2.8e-36
NP_001281268 (OMIM: 602989) dual specificity prote ( 271) 1379 132.0 2e-30
NP_065717 (OMIM: 607969) dual specificity protein ( 481) 1376 132.1 3.3e-30
NP_004062 (OMIM: 601951) dual specificity protein ( 484) 1330 128.2 5e-29
NP_001155879 (OMIM: 601951) dual specificity prote ( 526) 1330 128.2 5.3e-29
XP_011507449 (OMIM: 602989) PREDICTED: dual specif ( 252) 940 94.6 3.2e-19
XP_016855730 (OMIM: 602989) PREDICTED: dual specif ( 252) 940 94.6 3.2e-19
XP_016855731 (OMIM: 602989) PREDICTED: dual specif ( 252) 940 94.6 3.2e-19
XP_016855732 (OMIM: 602989) PREDICTED: dual specif ( 252) 940 94.6 3.2e-19
XP_016855733 (OMIM: 602989) PREDICTED: dual specif ( 252) 940 94.6 3.2e-19
XP_011507446 (OMIM: 602989) PREDICTED: dual specif ( 279) 525 59.4 1.4e-08
NP_003574 (OMIM: 603496) dual specificity tyrosine ( 528) 339 44.0 0.0012
XP_016875521 (OMIM: 603496) PREDICTED: dual specif ( 528) 339 44.0 0.0012
NP_006473 (OMIM: 603496) dual specificity tyrosine ( 601) 339 44.1 0.0013
NP_003836 (OMIM: 609181) dual specificity tyrosine ( 520) 328 43.0 0.0023
XP_011508363 (OMIM: 603497) PREDICTED: dual specif ( 553) 318 42.2 0.0043
XP_005273372 (OMIM: 603497) PREDICTED: dual specif ( 568) 318 42.2 0.0043
NP_001004023 (OMIM: 603497) dual specificity tyros ( 568) 318 42.2 0.0043
NP_003573 (OMIM: 603497) dual specificity tyrosine ( 588) 318 42.3 0.0044
>>NP_003983 (OMIM: 602990) dual specificity protein kina (490 aa)
initn: 2138 init1: 2138 opt: 2207 Z-score: 1044.9 bits: 202.7 E(85289): 1.8e-51
Smith-Waterman score: 3217; 95.3% identity (95.3% similar) in 490 aa overlap (1-467:1-490)
10 20 30 40 50 60
pF1KE5 MHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSHDRLPYQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSHDRLPYQRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 YRERRDSDTYRCEERSPSFGEDYYGPSRSRHRRRSRERGPYRTRKHAHHCHKRRTRSCSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YRERRDSDTYRCEERSPSFGEDYYGPSRSRHRRRSRERGPYRTRKHAHHCHKRRTRSCSS
70 80 90 100 110 120
130 140 150
pF1KE5 ASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYE-----------------------
:::::::::::::::::::::::::::::::::::::
NP_003 ASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE5 SQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLG
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE5 KNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLY
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE5 NEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSI
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE5 GCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSD
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE5 GRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEER
430 440 450 460 470 480
460
pF1KE5 SFHTSRNPSR
::::::::::
NP_003 SFHTSRNPSR
490
>>XP_016877399 (OMIM: 602990) PREDICTED: dual specificit (490 aa)
initn: 2138 init1: 2138 opt: 2207 Z-score: 1044.9 bits: 202.7 E(85289): 1.8e-51
Smith-Waterman score: 3217; 95.3% identity (95.3% similar) in 490 aa overlap (1-467:1-490)
10 20 30 40 50 60
pF1KE5 MHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSHDRLPYQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSHDRLPYQRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 YRERRDSDTYRCEERSPSFGEDYYGPSRSRHRRRSRERGPYRTRKHAHHCHKRRTRSCSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRERRDSDTYRCEERSPSFGEDYYGPSRSRHRRRSRERGPYRTRKHAHHCHKRRTRSCSS
70 80 90 100 110 120
130 140 150
pF1KE5 ASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYE-----------------------
:::::::::::::::::::::::::::::::::::::
XP_016 ASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE5 SQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLG
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE5 KNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLY
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE5 NEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSI
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE5 GCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSD
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE5 GRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEER
430 440 450 460 470 480
460
pF1KE5 SFHTSRNPSR
::::::::::
XP_016 SFHTSRNPSR
490
>>XP_016877398 (OMIM: 602990) PREDICTED: dual specificit (490 aa)
initn: 2138 init1: 2138 opt: 2207 Z-score: 1044.9 bits: 202.7 E(85289): 1.8e-51
Smith-Waterman score: 3217; 95.3% identity (95.3% similar) in 490 aa overlap (1-467:1-490)
10 20 30 40 50 60
pF1KE5 MHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSHDRLPYQRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSHDRLPYQRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 YRERRDSDTYRCEERSPSFGEDYYGPSRSRHRRRSRERGPYRTRKHAHHCHKRRTRSCSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRERRDSDTYRCEERSPSFGEDYYGPSRSRHRRRSRERGPYRTRKHAHHCHKRRTRSCSS
70 80 90 100 110 120
130 140 150
pF1KE5 ASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYE-----------------------
:::::::::::::::::::::::::::::::::::::
XP_016 ASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE5 SQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLG
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE5 KNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLY
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE5 NEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSI
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE5 GCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSD
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE5 GRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEER
430 440 450 460 470 480
460
pF1KE5 SFHTSRNPSR
::::::::::
XP_016 SFHTSRNPSR
490
>>NP_001123500 (OMIM: 602990) dual specificity protein k (638 aa)
initn: 2214 init1: 2138 opt: 2207 Z-score: 1043.7 bits: 202.9 E(85289): 2.1e-51
Smith-Waterman score: 3217; 95.3% identity (95.3% similar) in 490 aa overlap (1-467:149-638)
10 20 30
pF1KE5 MHHCKRYRSPEPDPYLSYRWKRRRSYSREH
::::::::::::::::::::::::::::::
NP_001 GLPRAEVAAGSGRGARSGEWGLAAAGAWETMHHCKRYRSPEPDPYLSYRWKRRRSYSREH
120 130 140 150 160 170
40 50 60 70 80 90
pF1KE5 EGRLRYPSRREPPPRRSRSRSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGRLRYPSRREPPPRRSRSRSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSR
180 190 200 210 220 230
100 110 120 130 140 150
pF1KE5 HRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGD
240 250 260 270 280 290
160 170 180
pF1KE5 WLQERYE-----------------------SQVALKIIRNVGKYREAARLEINVLKKIKE
::::::: ::::::::::::::::::::::::::::::
NP_001 WLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKE
300 310 320 330 340 350
190 200 210 220 230 240
pF1KE5 KDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHA
360 370 380 390 400 410
250 260 270 280 290 300
pF1KE5 LRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEH
420 430 440 450 460 470
310 320 330 340 350 360
pF1KE5 HTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKIL
480 490 500 510 520 530
370 380 390 400 410 420
pF1KE5 GPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMR
540 550 560 570 580 590
430 440 450 460
pF1KE5 RMLEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR
::::::::::::::::::::::::::::::::::::::::
NP_001 RMLEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR
600 610 620 630
>>XP_016877396 (OMIM: 602990) PREDICTED: dual specificit (655 aa)
initn: 2254 init1: 2138 opt: 2207 Z-score: 1043.6 bits: 202.9 E(85289): 2.2e-51
Smith-Waterman score: 3217; 95.3% identity (95.3% similar) in 490 aa overlap (1-467:166-655)
10 20 30
pF1KE5 MHHCKRYRSPEPDPYLSYRWKRRRSYSREH
::::::::::::::::::::::::::::::
XP_016 GEWGLAAAGAWETVSVGWGPRRRQRRRRPGMHHCKRYRSPEPDPYLSYRWKRRRSYSREH
140 150 160 170 180 190
40 50 60 70 80 90
pF1KE5 EGRLRYPSRREPPPRRSRSRSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGRLRYPSRREPPPRRSRSRSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSR
200 210 220 230 240 250
100 110 120 130 140 150
pF1KE5 HRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGD
260 270 280 290 300 310
160 170 180
pF1KE5 WLQERYE-----------------------SQVALKIIRNVGKYREAARLEINVLKKIKE
::::::: ::::::::::::::::::::::::::::::
XP_016 WLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKE
320 330 340 350 360 370
190 200 210 220 230 240
pF1KE5 KDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHA
380 390 400 410 420 430
250 260 270 280 290 300
pF1KE5 LRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEH
440 450 460 470 480 490
310 320 330 340 350 360
pF1KE5 HTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKIL
500 510 520 530 540 550
370 380 390 400 410 420
pF1KE5 GPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMR
560 570 580 590 600 610
430 440 450 460
pF1KE5 RMLEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR
::::::::::::::::::::::::::::::::::::::::
XP_016 RMLEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR
620 630 640 650
>>XP_005254208 (OMIM: 602990) PREDICTED: dual specificit (652 aa)
initn: 2514 init1: 2138 opt: 2187 Z-score: 1034.4 bits: 201.2 E(85289): 7.1e-51
Smith-Waterman score: 3133; 92.6% identity (92.6% similar) in 499 aa overlap (6-467:154-652)
10 20 30
pF1KE5 MHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLR
::::::::::::::::::::::::::::::
XP_005 EVAAGSGRGARSGEWGLAAAGAWETMHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLR
130 140 150 160 170 180
40 50 60 70 80
pF1KE5 YPSRREPPPRRSRSRS--------------HDRLPYQRRYRERRDSDTYRCEERSPSFGE
:::::::::::::::: ::::::::::::::::::::::::::::::
XP_005 YPSRREPPPRRSRSRSKDPADQRPHPPFGSHDRLPYQRRYRERRDSDTYRCEERSPSFGE
190 200 210 220 230 240
90 100 110 120 130 140
pF1KE5 DYYGPSRSRHRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DYYGPSRSRHRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKE
250 260 270 280 290 300
150 160 170
pF1KE5 GHLVCRIGDWLQERYE-----------------------SQVALKIIRNVGKYREAARLE
:::::::::::::::: :::::::::::::::::::::
XP_005 GHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLE
310 320 330 340 350 360
180 190 200 210 220 230
pF1KE5 INVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 INVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVR
370 380 390 400 410 420
240 250 260 270 280 290
pF1KE5 HMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADF
430 440 450 460 470 480
300 310 320 330 340 350
pF1KE5 GSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENRE
490 500 510 520 530 540
360 370 380 390 400 410
pF1KE5 HLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLE
550 560 570 580 590 600
420 430 440 450 460
pF1KE5 HVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR
610 620 630 640 650
>>XP_016877395 (OMIM: 602990) PREDICTED: dual specificit (669 aa)
initn: 2514 init1: 2138 opt: 2187 Z-score: 1034.3 bits: 201.2 E(85289): 7.2e-51
Smith-Waterman score: 3133; 92.6% identity (92.6% similar) in 499 aa overlap (6-467:171-669)
10 20 30
pF1KE5 MHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLR
::::::::::::::::::::::::::::::
XP_016 AAAGAWETVSVGWGPRRRQRRRRPGMHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLR
150 160 170 180 190 200
40 50 60 70 80
pF1KE5 YPSRREPPPRRSRSRS--------------HDRLPYQRRYRERRDSDTYRCEERSPSFGE
:::::::::::::::: ::::::::::::::::::::::::::::::
XP_016 YPSRREPPPRRSRSRSKDPADQRPHPPFGSHDRLPYQRRYRERRDSDTYRCEERSPSFGE
210 220 230 240 250 260
90 100 110 120 130 140
pF1KE5 DYYGPSRSRHRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYYGPSRSRHRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKE
270 280 290 300 310 320
150 160 170
pF1KE5 GHLVCRIGDWLQERYE-----------------------SQVALKIIRNVGKYREAARLE
:::::::::::::::: :::::::::::::::::::::
XP_016 GHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLE
330 340 350 360 370 380
180 190 200 210 220 230
pF1KE5 INVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVR
390 400 410 420 430 440
240 250 260 270 280 290
pF1KE5 HMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADF
450 460 470 480 490 500
300 310 320 330 340 350
pF1KE5 GSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENRE
510 520 530 540 550 560
360 370 380 390 400 410
pF1KE5 HLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLE
570 580 590 600 610 620
420 430 440 450 460
pF1KE5 HVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR
630 640 650 660
>>XP_011519508 (OMIM: 602990) PREDICTED: dual specificit (642 aa)
initn: 1828 init1: 1752 opt: 1822 Z-score: 866.8 bits: 170.2 E(85289): 1.5e-41
Smith-Waterman score: 2832; 94.1% identity (94.3% similar) in 437 aa overlap (1-413:149-585)
10 20 30
pF1KE5 MHHCKRYRSPEPDPYLSYRWKRRRSYSREH
::::::::::::::::::::::::::::::
XP_011 GLPRAEVAAGSGRGARSGEWGLAAAGAWETMHHCKRYRSPEPDPYLSYRWKRRRSYSREH
120 130 140 150 160 170
40 50 60 70 80 90
pF1KE5 EGRLRYPSRREPPPRRSRSRSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGRLRYPSRREPPPRRSRSRSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSR
180 190 200 210 220 230
100 110 120 130 140 150
pF1KE5 HRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGD
240 250 260 270 280 290
160 170 180
pF1KE5 WLQERYE-----------------------SQVALKIIRNVGKYREAARLEINVLKKIKE
::::::: ::::::::::::::::::::::::::::::
XP_011 WLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKE
300 310 320 330 340 350
190 200 210 220 230 240
pF1KE5 KDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHA
360 370 380 390 400 410
250 260 270 280 290 300
pF1KE5 LRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEH
420 430 440 450 460 470
310 320 330 340 350 360
pF1KE5 HTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKIL
480 490 500 510 520 530
370 380 390 400 410 420
pF1KE5 GPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLK-SYMLQDSLEHVQLFDLM
:::::::::::::::::::::::::::::::::::::::::: :. :
XP_011 GPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKVSFWLPPAELMPRRDPRH
540 550 560 570 580 590
430 440 450 460
pF1KE5 RRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR
XP_011 WADIQQRQARPLKAASLIQLYGRRHPRLLGAGNGASCKLPQRGP
600 610 620 630 640
>>XP_011519511 (OMIM: 602990) PREDICTED: dual specificit (659 aa)
initn: 1868 init1: 1752 opt: 1822 Z-score: 866.7 bits: 170.2 E(85289): 1.6e-41
Smith-Waterman score: 2832; 94.1% identity (94.3% similar) in 437 aa overlap (1-413:166-602)
10 20 30
pF1KE5 MHHCKRYRSPEPDPYLSYRWKRRRSYSREH
::::::::::::::::::::::::::::::
XP_011 GEWGLAAAGAWETVSVGWGPRRRQRRRRPGMHHCKRYRSPEPDPYLSYRWKRRRSYSREH
140 150 160 170 180 190
40 50 60 70 80 90
pF1KE5 EGRLRYPSRREPPPRRSRSRSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGRLRYPSRREPPPRRSRSRSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSR
200 210 220 230 240 250
100 110 120 130 140 150
pF1KE5 HRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGD
260 270 280 290 300 310
160 170 180
pF1KE5 WLQERYE-----------------------SQVALKIIRNVGKYREAARLEINVLKKIKE
::::::: ::::::::::::::::::::::::::::::
XP_011 WLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKE
320 330 340 350 360 370
190 200 210 220 230 240
pF1KE5 KDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHA
380 390 400 410 420 430
250 260 270 280 290 300
pF1KE5 LRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEH
440 450 460 470 480 490
310 320 330 340 350 360
pF1KE5 HTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKIL
500 510 520 530 540 550
370 380 390 400 410 420
pF1KE5 GPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLK-SYMLQDSLEHVQLFDLM
:::::::::::::::::::::::::::::::::::::::::: :. :
XP_011 GPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKVSFWLPPAELMPRRDPRH
560 570 580 590 600 610
430 440 450 460
pF1KE5 RRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR
XP_011 WADIQQRQARPLKAASLIQLYGRRHPRLLGAGNGASCKLPQRGP
620 630 640 650
>>XP_016877397 (OMIM: 602990) PREDICTED: dual specificit (508 aa)
initn: 2154 init1: 1752 opt: 1802 Z-score: 858.7 bits: 168.3 E(85289): 4.3e-41
Smith-Waterman score: 2748; 91.0% identity (91.3% similar) in 446 aa overlap (6-413:6-451)
10 20 30 40 50
pF1KE5 MHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRS---------
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSKDPADQRPH
10 20 30 40 50 60
60 70 80 90 100
pF1KE5 -----HDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSRHRRRSRERGPYRTRKH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPFGSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSRHRRRSRERGPYRTRKH
70 80 90 100 110 120
110 120 130 140 150
pF1KE5 AHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYE---------
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGT
130 140 150 160 170 180
160 170 180 190 200
pF1KE5 --------------SQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWF
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWF
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE5 NFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKP
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE5 ENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVI
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE5 LELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKY
370 380 390 400 410 420
390 400 410 420 430 440
pF1KE5 FYKGGLVWDENSSDGRYVKENCKPLK-SYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAE
:::::::::::::::::::::::::: :. :
XP_016 FYKGGLVWDENSSDGRYVKENCKPLKVSFWLPPAELMPRRDPRHWADIQQRQARPLKAAS
430 440 450 460 470 480
450 460
pF1KE5 ALLHPFFAGLTPEERSFHTSRNPSR
XP_016 LIQLYGRRHPRLLGAGNGASCKLPQRGP
490 500
467 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 04:04:59 2016 done: Tue Nov 8 04:05:00 2016
Total Scan time: 8.090 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]