Result of FASTA (omim) for
pFN21AE3317
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3317, 879 aa
1>>>pF1KE3317 879 - 879 aa - 879 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 16.3282+/-0.000666; mu= -34.9215+/- 0.040
mean_var=977.7311+/-218.977, 0's: 0 Z-trim(113.8): 614 B-trim: 1381 in 1/56
Lambda= 0.041017
statistics sampled from 22687 (23307) to 22687 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.273), width: 16
Scan time: 10.370
The best scores are: opt bits E(85289)
NP_001165774 (OMIM: 188000,608221) serine/threonin ( 879) 5837 363.2 3.1e-99
NP_116233 (OMIM: 188000,608221) serine/threonine-p ( 878) 5818 362.1 6.7e-99
NP_001307686 (OMIM: 188000,608221) serine/threonin ( 884) 5817 362.0 7e-99
NP_001307685 (OMIM: 188000,608221) serine/threonin ( 883) 5798 360.9 1.5e-98
XP_016872342 (OMIM: 188000,608221) PREDICTED: seri ( 835) 5409 337.8 1.3e-91
XP_016872343 (OMIM: 188000,608221) PREDICTED: seri ( 798) 5261 329.1 5.3e-89
XP_016872344 (OMIM: 188000,608221) PREDICTED: seri ( 797) 5242 327.9 1.1e-88
XP_006717583 (OMIM: 188000,608221) PREDICTED: seri ( 803) 5241 327.9 1.2e-88
XP_016872341 (OMIM: 188000,608221) PREDICTED: seri ( 844) 5238 327.7 1.4e-88
XP_006717582 (OMIM: 188000,608221) PREDICTED: seri ( 850) 5237 327.7 1.5e-88
XP_005252689 (OMIM: 188000,608221) PREDICTED: seri ( 807) 4993 313.2 3.2e-84
XP_005252688 (OMIM: 188000,608221) PREDICTED: seri ( 841) 4976 312.2 6.5e-84
NP_001165775 (OMIM: 188000,608221) serine/threonin ( 840) 4957 311.1 1.4e-83
XP_016872345 (OMIM: 188000,608221) PREDICTED: seri ( 709) 4654 293.1 3.2e-78
XP_011518053 (OMIM: 188000,608221) PREDICTED: seri ( 547) 3622 231.9 6.4e-60
XP_016865715 (OMIM: 606964) PREDICTED: serine/thre ( 439) 466 45.0 0.00092
XP_006715051 (OMIM: 606964) PREDICTED: serine/thre ( 465) 466 45.1 0.00096
NP_001292031 (OMIM: 606964) serine/threonine-prote ( 465) 466 45.1 0.00096
XP_006715052 (OMIM: 606964) PREDICTED: serine/thre ( 465) 466 45.1 0.00096
NP_009202 (OMIM: 606964) serine/threonine-protein ( 465) 466 45.1 0.00096
XP_006719122 (OMIM: 615836) PREDICTED: serine/thre ( 412) 462 44.8 0.001
XP_006719121 (OMIM: 615836) PREDICTED: serine/thre ( 464) 462 44.8 0.0011
NP_055815 (OMIM: 615836) serine/threonine-protein ( 464) 462 44.8 0.0011
XP_016874525 (OMIM: 615836) PREDICTED: serine/thre ( 464) 462 44.8 0.0011
XP_011526107 (OMIM: 612256) PREDICTED: microtubule (1566) 478 46.3 0.0013
NP_055790 (OMIM: 612256) microtubule-associated se (1570) 478 46.3 0.0013
XP_006722761 (OMIM: 612258) PREDICTED: microtubule (1243) 463 45.3 0.0021
XP_016882003 (OMIM: 612258) PREDICTED: microtubule (1243) 463 45.3 0.0021
XP_016882004 (OMIM: 612258) PREDICTED: microtubule (1243) 463 45.3 0.0021
NP_055831 (OMIM: 612258) microtubule-associated se (1309) 463 45.4 0.0022
XP_006722763 (OMIM: 612258) PREDICTED: microtubule (1314) 463 45.4 0.0022
XP_011539371 (OMIM: 612257) PREDICTED: microtubule (1397) 464 45.5 0.0022
XP_005259884 (OMIM: 612258) PREDICTED: microtubule (1315) 463 45.4 0.0022
XP_016882002 (OMIM: 612258) PREDICTED: microtubule (1317) 463 45.4 0.0022
XP_016882001 (OMIM: 612258) PREDICTED: microtubule (1318) 463 45.4 0.0022
XP_005259883 (OMIM: 612258) PREDICTED: microtubule (1323) 463 45.4 0.0022
XP_005259882 (OMIM: 612258) PREDICTED: microtubule (1324) 463 45.4 0.0022
XP_005259881 (OMIM: 612258) PREDICTED: microtubule (1325) 463 45.4 0.0022
XP_005259880 (OMIM: 612258) PREDICTED: microtubule (1331) 463 45.4 0.0022
XP_016882000 (OMIM: 612258) PREDICTED: microtubule (1347) 463 45.4 0.0022
XP_011526125 (OMIM: 612258) PREDICTED: microtubule (1355) 463 45.4 0.0022
XP_016881999 (OMIM: 612258) PREDICTED: microtubule (1403) 463 45.4 0.0023
XP_016882005 (OMIM: 612258) PREDICTED: microtubule (1409) 463 45.4 0.0023
XP_016881998 (OMIM: 612258) PREDICTED: microtubule (1410) 463 45.4 0.0023
XP_016881997 (OMIM: 612258) PREDICTED: microtubule (1411) 463 45.4 0.0023
XP_016881996 (OMIM: 612258) PREDICTED: microtubule (1412) 463 45.4 0.0023
XP_016881995 (OMIM: 612258) PREDICTED: microtubule (1418) 463 45.4 0.0023
XP_006722762 (OMIM: 612258) PREDICTED: microtubule (1419) 463 45.4 0.0023
XP_011523404 (OMIM: 608938) PREDICTED: ribosomal p ( 391) 441 43.5 0.0024
XP_011539370 (OMIM: 612257) PREDICTED: microtubule (1636) 464 45.5 0.0024
>>NP_001165774 (OMIM: 188000,608221) serine/threonine-pr (879 aa)
initn: 5837 init1: 5837 opt: 5837 Z-score: 1902.6 bits: 363.2 E(85289): 3.1e-99
Smith-Waterman score: 5837; 99.9% identity (99.9% similar) in 879 aa overlap (1-879:1-879)
10 20 30 40 50 60
pF1KE3 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 ESNIEDPLIVTPDCQEKTSAKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 ESNIEDPLIVTPDCQEKTSPKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQQTPNQIKSGTPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQQTPNQIKSGTPY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFND
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 ETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVEILLTIDDTKRAGMKELKRHPLFSDVDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVEILLTIDDTKRAGMKELKRHPLFSDVDW
790 800 810 820 830 840
850 860 870
pF1KE3 ENLQHQTMPFIPQPDDETDTSYFEARNTAQHLTVSGFSL
:::::::::::::::::::::::::::::::::::::::
NP_001 ENLQHQTMPFIPQPDDETDTSYFEARNTAQHLTVSGFSL
850 860 870
>>NP_116233 (OMIM: 188000,608221) serine/threonine-prote (878 aa)
initn: 4654 init1: 4654 opt: 5818 Z-score: 1896.5 bits: 362.1 E(85289): 6.7e-99
Smith-Waterman score: 5818; 99.8% identity (99.8% similar) in 879 aa overlap (1-879:1-878)
10 20 30 40 50 60
pF1KE3 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 ESNIEDPLIVTPDCQEKTSAKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_116 ESNIEDPLIVTPDCQEKTSPKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQQTPNQIKSGTPY
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
NP_116 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQ-TPNQIKSGTPY
670 680 690 700 710
730 740 750 760 770 780
pF1KE3 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFND
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE3 ETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVEILLTIDDTKRAGMKELKRHPLFSDVDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_116 ETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVEILLTIDDTKRAGMKELKRHPLFSDVDW
780 790 800 810 820 830
850 860 870
pF1KE3 ENLQHQTMPFIPQPDDETDTSYFEARNTAQHLTVSGFSL
:::::::::::::::::::::::::::::::::::::::
NP_116 ENLQHQTMPFIPQPDDETDTSYFEARNTAQHLTVSGFSL
840 850 860 870
>>NP_001307686 (OMIM: 188000,608221) serine/threonine-pr (884 aa)
initn: 4981 init1: 4981 opt: 5817 Z-score: 1896.2 bits: 362.0 E(85289): 7e-99
Smith-Waterman score: 5817; 99.3% identity (99.3% similar) in 884 aa overlap (1-879:1-884)
10 20 30 40 50 60
pF1KE3 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 ESNIEDPLIVTPDCQEKTSAKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 ESNIEDPLIVTPDCQEKTSPKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQQTPNQIKSGTPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQQTPNQIKSGTPY
670 680 690 700 710 720
730 740 750 760 770
pF1KE3 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHG-----PAVDWWALGVCLFEFLTGI
:::::::::::::::::::::::::::::::::::: :::::::::::::::::::
NP_001 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGFLTSGPAVDWWALGVCLFEFLTGI
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE3 PPFNDETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVEILLTIDDTKRAGMKELKRHPLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPFNDETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVEILLTIDDTKRAGMKELKRHPLF
790 800 810 820 830 840
840 850 860 870
pF1KE3 SDVDWENLQHQTMPFIPQPDDETDTSYFEARNTAQHLTVSGFSL
::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDVDWENLQHQTMPFIPQPDDETDTSYFEARNTAQHLTVSGFSL
850 860 870 880
>>NP_001307685 (OMIM: 188000,608221) serine/threonine-pr (883 aa)
initn: 5504 init1: 4654 opt: 5798 Z-score: 1890.1 bits: 360.9 E(85289): 1.5e-98
Smith-Waterman score: 5798; 99.2% identity (99.2% similar) in 884 aa overlap (1-879:1-883)
10 20 30 40 50 60
pF1KE3 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 ESNIEDPLIVTPDCQEKTSAKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 ESNIEDPLIVTPDCQEKTSPKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQQTPNQIKSGTPY
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
NP_001 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQ-TPNQIKSGTPY
670 680 690 700 710
730 740 750 760 770
pF1KE3 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHG-----PAVDWWALGVCLFEFLTGI
:::::::::::::::::::::::::::::::::::: :::::::::::::::::::
NP_001 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGFLTSGPAVDWWALGVCLFEFLTGI
720 730 740 750 760 770
780 790 800 810 820 830
pF1KE3 PPFNDETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVEILLTIDDTKRAGMKELKRHPLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPFNDETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVEILLTIDDTKRAGMKELKRHPLF
780 790 800 810 820 830
840 850 860 870
pF1KE3 SDVDWENLQHQTMPFIPQPDDETDTSYFEARNTAQHLTVSGFSL
::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDVDWENLQHQTMPFIPQPDDETDTSYFEARNTAQHLTVSGFSL
840 850 860 870 880
>>XP_016872342 (OMIM: 188000,608221) PREDICTED: serine/t (835 aa)
initn: 4573 init1: 4573 opt: 5409 Z-score: 1766.0 bits: 337.8 E(85289): 1.3e-91
Smith-Waterman score: 5409; 99.3% identity (99.3% similar) in 822 aa overlap (63-879:14-835)
40 50 60 70 80 90
pF1KE3 EEFSIVKPISRGAFGKVYLGQKGGKLYAVKVVKKADMINKNMTHQVQAERDALALSKSPF
::::::::::::::::::::::::::::::
XP_016 MMSVGPRSPPTKSVVKKADMINKNMTHQVQAERDALALSKSPF
10 20 30 40
100 110 120 130 140 150
pF1KE3 IVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHRHGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVHLYYSLQSANNVYLVMEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHRHGI
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE3 IHRDLKPDNMLISNEGHIKLTDFGLSKVTLNRDINMMDILTTPSMAKPRQDYSRTPGQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IHRDLKPDNMLISNEGHIKLTDFGLSKVTLNRDINMMDILTTPSMAKPRQDYSRTPGQVL
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE3 SLISSLGFNTPIAEKNQDPANILSACLSETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLISSLGFNTPIAEKNQDPANILSACLSETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCL
170 180 190 200 210 220
280 290 300 310 320 330
pF1KE3 ETVASNPGMPVKCLTSNLLQSRKRLATSSASSQSHTFISSVESECHSSPKWEKDCQESDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETVASNPGMPVKCLTSNLLQSRKRLATSSASSQSHTFISSVESECHSSPKWEKDCQESDE
230 240 250 260 270 280
340 350 360 370 380 390
pF1KE3 ALGPTMMSWNAVEKLCAKSANAIETKGFNKKDLELALSPIHNSSALPTTGRSCVNLAKKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALGPTMMSWNAVEKLCAKSANAIETKGFNKKDLELALSPIHNSSALPTTGRSCVNLAKKC
290 300 310 320 330 340
400 410 420 430 440 450
pF1KE3 FSGEVSWEAVELDVNNINMDTDTSQLGFHQSNQWAVDSGGISEEHLGKRSLKRNFELVDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSGEVSWEAVELDVNNINMDTDTSQLGFHQSNQWAVDSGGISEEHLGKRSLKRNFELVDS
350 360 370 380 390 400
460 470 480 490 500 510
pF1KE3 SPCKKIIQNKKTCVEYKHNEMTNCYTNQNTGLTVEVQDLKLSVHKSQQNDCANKENIVNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPCKKIIQNKKTCVEYKHNEMTNCYTNQNTGLTVEVQDLKLSVHKSQQNDCANKENIVNS
410 420 430 440 450 460
520 530 540 550 560 570
pF1KE3 FTDKQQTPEKLPIPMIAKNLMCELDEDCEKNSKRDYLSSSFLCSDDDRASKNISMNSDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FTDKQQTPEKLPIPMIAKNLMCELDEDCEKNSKRDYLSSSFLCSDDDRASKNISMNSDSS
470 480 490 500 510 520
580 590 600 610 620 630
pF1KE3 FPGISIMESPLESQPLDSDRSIKESSFEESNIEDPLIVTPDCQEKTSAKGVENPAVQESN
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_016 FPGISIMESPLESQPLDSDRSIKESSFEESNIEDPLIVTPDCQEKTSPKGVENPAVQESN
530 540 550 560 570 580
640 650 660 670 680 690
pF1KE3 QKMLGPPLEVLKTLASKRNAVAFRSFNSHINASNNSEPSRMNMTSLDAMDISCAYSGSYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKMLGPPLEVLKTLASKRNAVAFRSFNSHINASNNSEPSRMNMTSLDAMDISCAYSGSYP
590 600 610 620 630 640
700 710 720 730 740 750
pF1KE3 MAITPTQKRRSCMPHQQTPNQIKSGTPYRTPKSVRRGVAPVDDGRILGTPDYLAPELLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAITPTQKRRSCMPHQQTPNQIKSGTPYRTPKSVRRGVAPVDDGRILGTPDYLAPELLLG
650 660 670 680 690 700
760 770 780 790 800
pF1KE3 RAHG-----PAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEEKLSDN
:::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAHGFLTSGPAVDWWALGVCLFEFLTGIPPFNDETPQQVFQNILKRDIPWPEGEEKLSDN
710 720 730 740 750 760
810 820 830 840 850 860
pF1KE3 AQSAVEILLTIDDTKRAGMKELKRHPLFSDVDWENLQHQTMPFIPQPDDETDTSYFEARN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQSAVEILLTIDDTKRAGMKELKRHPLFSDVDWENLQHQTMPFIPQPDDETDTSYFEARN
770 780 790 800 810 820
870
pF1KE3 TAQHLTVSGFSL
::::::::::::
XP_016 TAQHLTVSGFSL
830
>>XP_016872343 (OMIM: 188000,608221) PREDICTED: serine/t (798 aa)
initn: 5261 init1: 5261 opt: 5261 Z-score: 1718.9 bits: 329.1 E(85289): 5.3e-89
Smith-Waterman score: 5261; 99.9% identity (99.9% similar) in 794 aa overlap (1-794:1-794)
10 20 30 40 50 60
pF1KE3 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 ESNIEDPLIVTPDCQEKTSAKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_016 ESNIEDPLIVTPDCQEKTSPKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQQTPNQIKSGTPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQQTPNQIKSGTPY
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFND
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 ETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVEILLTIDDTKRAGMKELKRHPLFSDVDW
::::::::::::::
XP_016 ETPQQVFQNILKRDGEYL
790
>>XP_016872344 (OMIM: 188000,608221) PREDICTED: serine/t (797 aa)
initn: 4654 init1: 4654 opt: 5242 Z-score: 1712.8 bits: 327.9 E(85289): 1.1e-88
Smith-Waterman score: 5242; 99.7% identity (99.7% similar) in 794 aa overlap (1-794:1-793)
10 20 30 40 50 60
pF1KE3 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 ESNIEDPLIVTPDCQEKTSAKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_016 ESNIEDPLIVTPDCQEKTSPKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQQTPNQIKSGTPY
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQ-TPNQIKSGTPY
670 680 690 700 710
730 740 750 760 770 780
pF1KE3 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFND
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE3 ETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVEILLTIDDTKRAGMKELKRHPLFSDVDW
::::::::::::::
XP_016 ETPQQVFQNILKRDGEYL
780 790
>>XP_006717583 (OMIM: 188000,608221) PREDICTED: serine/t (803 aa)
initn: 4981 init1: 4981 opt: 5241 Z-score: 1712.5 bits: 327.9 E(85289): 1.2e-88
Smith-Waterman score: 5241; 99.2% identity (99.2% similar) in 799 aa overlap (1-794:1-799)
10 20 30 40 50 60
pF1KE3 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 ESNIEDPLIVTPDCQEKTSAKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_006 ESNIEDPLIVTPDCQEKTSPKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQQTPNQIKSGTPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQQTPNQIKSGTPY
670 680 690 700 710 720
730 740 750 760 770
pF1KE3 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHG-----PAVDWWALGVCLFEFLTGI
:::::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_006 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGFLTSGPAVDWWALGVCLFEFLTGI
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE3 PPFNDETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVEILLTIDDTKRAGMKELKRHPLF
:::::::::::::::::::
XP_006 PPFNDETPQQVFQNILKRDGEYL
790 800
>>XP_016872341 (OMIM: 188000,608221) PREDICTED: serine/t (844 aa)
initn: 5243 init1: 4654 opt: 5238 Z-score: 1711.3 bits: 327.7 E(85289): 1.4e-88
Smith-Waterman score: 5517; 95.9% identity (95.9% similar) in 879 aa overlap (1-879:1-844)
10 20 30 40 50 60
pF1KE3 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 ESNIEDPLIVTPDCQEKTSAKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_016 ESNIEDPLIVTPDCQEKTSPKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQQTPNQIKSGTPY
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_016 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQ-TPNQIKSGTPY
670 680 690 700 710
730 740 750 760 770 780
pF1KE3 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGPAVDWWALGVCLFEFLTGIPPFND
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE3 ETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVEILLTIDDTKRAGMKELKRHPLFSDVDW
::::::::::::: :::::::::::::
XP_016 ETPQQVFQNILKR----------------------------------ELKRHPLFSDVDW
780 790 800
850 860 870
pF1KE3 ENLQHQTMPFIPQPDDETDTSYFEARNTAQHLTVSGFSL
:::::::::::::::::::::::::::::::::::::::
XP_016 ENLQHQTMPFIPQPDDETDTSYFEARNTAQHLTVSGFSL
810 820 830 840
>>XP_006717582 (OMIM: 188000,608221) PREDICTED: serine/t (850 aa)
initn: 5331 init1: 4981 opt: 5237 Z-score: 1710.9 bits: 327.7 E(85289): 1.5e-88
Smith-Waterman score: 5516; 95.5% identity (95.5% similar) in 884 aa overlap (1-879:1-850)
10 20 30 40 50 60
pF1KE3 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MDPTAGSKKEPGGGAATEEGVNRIAVPKPPSIEEFSIVKPISRGAFGKVYLGQKGGKLYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VKVVKKADMINKNMTHQVQAERDALALSKSPFIVHLYYSLQSANNVYLVMEYLIGGDVKS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGHIKLTDFGLSKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TLNRDINMMDILTTPSMAKPRQDYSRTPGQVLSLISSLGFNTPIAEKNQDPANILSACLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETSQLSQGLVCPMSVDQKDTTPYSSKLLKSCLETVASNPGMPVKCLTSNLLQSRKRLATS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SASSQSHTFISSVESECHSSPKWEKDCQESDEALGPTMMSWNAVEKLCAKSANAIETKGF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKKDLELALSPIHNSSALPTTGRSCVNLAKKCFSGEVSWEAVELDVNNINMDTDTSQLGF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HQSNQWAVDSGGISEEHLGKRSLKRNFELVDSSPCKKIIQNKKTCVEYKHNEMTNCYTNQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NTGLTVEVQDLKLSVHKSQQNDCANKENIVNSFTDKQQTPEKLPIPMIAKNLMCELDEDC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKNSKRDYLSSSFLCSDDDRASKNISMNSDSSFPGISIMESPLESQPLDSDRSIKESSFE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 ESNIEDPLIVTPDCQEKTSAKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
XP_006 ESNIEDPLIVTPDCQEKTSPKGVENPAVQESNQKMLGPPLEVLKTLASKRNAVAFRSFNS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQQTPNQIKSGTPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HINASNNSEPSRMNMTSLDAMDISCAYSGSYPMAITPTQKRRSCMPHQQTPNQIKSGTPY
670 680 690 700 710 720
730 740 750 760 770
pF1KE3 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHG-----PAVDWWALGVCLFEFLTGI
:::::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_006 RTPKSVRRGVAPVDDGRILGTPDYLAPELLLGRAHGFLTSGPAVDWWALGVCLFEFLTGI
730 740 750 760 770 780
780 790 800 810 820 830
pF1KE3 PPFNDETPQQVFQNILKRDIPWPEGEEKLSDNAQSAVEILLTIDDTKRAGMKELKRHPLF
:::::::::::::::::: ::::::::
XP_006 PPFNDETPQQVFQNILKR----------------------------------ELKRHPLF
790 800
840 850 860 870
pF1KE3 SDVDWENLQHQTMPFIPQPDDETDTSYFEARNTAQHLTVSGFSL
::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDVDWENLQHQTMPFIPQPDDETDTSYFEARNTAQHLTVSGFSL
810 820 830 840 850
879 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 02:15:15 2016 done: Tue Nov 8 02:15:17 2016
Total Scan time: 10.370 Total Display time: 0.260
Function used was FASTA [36.3.4 Apr, 2011]