Result of FASTA (omim) for
pFN21AE5261
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5261, 186 aa
1>>>pF1KE5261 186 - 186 aa - 186 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6270+/-0.000396; mu= 16.5341+/- 0.024
mean_var=63.7109+/-13.534, 0's: 0 Z-trim(111.9): 241 B-trim: 815 in 1/53
Lambda= 0.160682
statistics sampled from 20292 (20581) to 20292 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.611), E-opt: 0.2 (0.241), width: 16
Scan time: 5.720
The best scores are: opt bits E(85289)
NP_001158268 (OMIM: 611037,616794) S-adenosylmethi ( 186) 1216 290.4 1.1e-78
XP_011531629 (OMIM: 611037,616794) PREDICTED: S-ad ( 186) 1216 290.4 1.1e-78
NP_775742 (OMIM: 611037,616794) S-adenosylmethioni ( 274) 1216 290.6 1.5e-78
XP_016861161 (OMIM: 611037,616794) PREDICTED: S-ad ( 198) 824 199.6 2.6e-51
XP_016861162 (OMIM: 611037,616794) PREDICTED: S-ad ( 198) 824 199.6 2.6e-51
XP_016861160 (OMIM: 611037,616794) PREDICTED: S-ad ( 286) 824 199.7 3.5e-51
XP_016861163 (OMIM: 611037,616794) PREDICTED: S-ad ( 171) 720 175.4 4.3e-44
XP_006713019 (OMIM: 611037,616794) PREDICTED: S-ad ( 259) 720 175.6 5.8e-44
XP_011531630 (OMIM: 611037,616794) PREDICTED: S-ad ( 162) 407 102.8 2.9e-22
XP_011510372 (OMIM: 603667,612949) PREDICTED: calc ( 587) 258 68.8 1.9e-11
NP_003696 (OMIM: 603667,612949) calcium-binding mi ( 678) 258 68.8 2.1e-11
XP_016867154 (OMIM: 603471,603859,605814) PREDICTE ( 391) 244 65.4 1.3e-10
XP_016867153 (OMIM: 603471,603859,605814) PREDICTE ( 391) 244 65.4 1.3e-10
XP_016867152 (OMIM: 603471,603859,605814) PREDICTE ( 672) 244 65.6 2e-10
NP_055066 (OMIM: 603471,603859,605814) calcium-bin ( 675) 244 65.6 2e-10
NP_001153682 (OMIM: 603471,603859,605814) calcium- ( 676) 244 65.6 2e-10
XP_006715894 (OMIM: 603471,603859,605814) PREDICTE ( 686) 244 65.6 2e-10
XP_011535591 (OMIM: 607571) PREDICTED: mitochondri ( 267) 233 62.7 5.8e-10
XP_011535590 (OMIM: 607571) PREDICTED: mitochondri ( 269) 233 62.7 5.8e-10
NP_001164641 (OMIM: 607571) mitochondrial 2-oxodic ( 298) 233 62.7 6.3e-10
NP_085134 (OMIM: 607571) mitochondrial 2-oxodicarb ( 299) 233 62.7 6.3e-10
XP_011535589 (OMIM: 607571) PREDICTED: mitochondri ( 303) 233 62.7 6.3e-10
XP_016884461 (OMIM: 609303) PREDICTED: mitochondri ( 272) 229 61.8 1.1e-09
XP_016884460 (OMIM: 609303) PREDICTED: mitochondri ( 272) 229 61.8 1.1e-09
XP_016884463 (OMIM: 609303) PREDICTED: mitochondri ( 272) 229 61.8 1.1e-09
XP_016884459 (OMIM: 609303) PREDICTED: mitochondri ( 272) 229 61.8 1.1e-09
XP_016884464 (OMIM: 609303) PREDICTED: mitochondri ( 272) 229 61.8 1.1e-09
XP_016884458 (OMIM: 609303) PREDICTED: mitochondri ( 272) 229 61.8 1.1e-09
XP_016884462 (OMIM: 609303) PREDICTED: mitochondri ( 272) 229 61.8 1.1e-09
NP_113669 (OMIM: 609303) mitochondrial glutamate c ( 315) 229 61.8 1.2e-09
XP_011544455 (OMIM: 609303) PREDICTED: mitochondri ( 315) 229 61.8 1.2e-09
NP_001290413 (OMIM: 609303) mitochondrial glutamat ( 315) 229 61.8 1.2e-09
XP_016884457 (OMIM: 609303) PREDICTED: mitochondri ( 315) 229 61.8 1.2e-09
XP_011544454 (OMIM: 609303) PREDICTED: mitochondri ( 315) 229 61.8 1.2e-09
XP_011544456 (OMIM: 609303) PREDICTED: mitochondri ( 315) 229 61.8 1.2e-09
XP_011544453 (OMIM: 609303) PREDICTED: mitochondri ( 315) 229 61.8 1.2e-09
XP_011544452 (OMIM: 609303) PREDICTED: mitochondri ( 366) 229 61.9 1.4e-09
XP_011544451 (OMIM: 609303) PREDICTED: mitochondri ( 410) 229 61.9 1.5e-09
XP_006716415 (OMIM: 610387) PREDICTED: mitoferrin- ( 266) 223 60.4 2.9e-09
NP_001304743 (OMIM: 610387) mitoferrin-1 isoform 3 ( 266) 223 60.4 2.9e-09
XP_011542855 (OMIM: 610387) PREDICTED: mitoferrin- ( 266) 223 60.4 2.9e-09
NP_001304742 (OMIM: 610387) mitoferrin-1 isoform 3 ( 266) 223 60.4 2.9e-09
XP_016869021 (OMIM: 610387) PREDICTED: mitoferrin- ( 266) 223 60.4 2.9e-09
XP_011542852 (OMIM: 610387) PREDICTED: mitoferrin- ( 272) 223 60.4 2.9e-09
NP_057696 (OMIM: 610387) mitoferrin-1 isoform 1 [H ( 338) 223 60.4 3.4e-09
XP_011518671 (OMIM: 609302,609304) PREDICTED: mito ( 323) 221 60.0 4.6e-09
NP_001177990 (OMIM: 609302,609304) mitochondrial g ( 323) 221 60.0 4.6e-09
XP_011518673 (OMIM: 609302,609304) PREDICTED: mito ( 323) 221 60.0 4.6e-09
NP_001177989 (OMIM: 609302,609304) mitochondrial g ( 323) 221 60.0 4.6e-09
NP_078974 (OMIM: 609302,609304) mitochondrial glut ( 323) 221 60.0 4.6e-09
>>NP_001158268 (OMIM: 611037,616794) S-adenosylmethionin (186 aa)
initn: 1216 init1: 1216 opt: 1216 Z-score: 1533.5 bits: 290.4 E(85289): 1.1e-78
Smith-Waterman score: 1216; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:1-186)
10 20 30 40 50 60
pF1KE5 MKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQGLYRGYKSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQGLYRGYKSTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LREIPFSLVQFPLWESLKALWSWRQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LREIPFSLVQFPLWESLKALWSWRQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRIT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LAKAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAISLGGFIFLGAYDRTHSLLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAKAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAISLGGFIFLGAYDRTHSLLLE
130 140 150 160 170 180
pF1KE5 VGRKSP
::::::
NP_001 VGRKSP
>>XP_011531629 (OMIM: 611037,616794) PREDICTED: S-adenos (186 aa)
initn: 1216 init1: 1216 opt: 1216 Z-score: 1533.5 bits: 290.4 E(85289): 1.1e-78
Smith-Waterman score: 1216; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:1-186)
10 20 30 40 50 60
pF1KE5 MKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQGLYRGYKSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQGLYRGYKSTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LREIPFSLVQFPLWESLKALWSWRQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREIPFSLVQFPLWESLKALWSWRQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRIT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE5 LAKAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAISLGGFIFLGAYDRTHSLLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAISLGGFIFLGAYDRTHSLLLE
130 140 150 160 170 180
pF1KE5 VGRKSP
::::::
XP_011 VGRKSP
>>NP_775742 (OMIM: 611037,616794) S-adenosylmethionine m (274 aa)
initn: 1216 init1: 1216 opt: 1216 Z-score: 1531.3 bits: 290.6 E(85289): 1.5e-78
Smith-Waterman score: 1216; 100.0% identity (100.0% similar) in 186 aa overlap (1-186:89-274)
10 20 30
pF1KE5 MKHMLAASAGEVVACLIRVPSEVVKQRAQV
::::::::::::::::::::::::::::::
NP_775 GSFPNAAAFFITYEYVKWFLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVKQRAQV
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE5 SASTRTFQIFSNILYEEGIQGLYRGYKSTVLREIPFSLVQFPLWESLKALWSWRQDHVVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 SASTRTFQIFSNILYEEGIQGLYRGYKSTVLREIPFSLVQFPLWESLKALWSWRQDHVVD
120 130 140 150 160 170
100 110 120 130 140 150
pF1KE5 SWQSAVCGAFAGGFAAAVTTPLDVAKTRITLAKAGSSTADGNVLSVLHGVWRSQGLAGLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 SWQSAVCGAFAGGFAAAVTTPLDVAKTRITLAKAGSSTADGNVLSVLHGVWRSQGLAGLF
180 190 200 210 220 230
160 170 180
pF1KE5 AGVFPRMAAISLGGFIFLGAYDRTHSLLLEVGRKSP
::::::::::::::::::::::::::::::::::::
NP_775 AGVFPRMAAISLGGFIFLGAYDRTHSLLLEVGRKSP
240 250 260 270
>>XP_016861161 (OMIM: 611037,616794) PREDICTED: S-adenos (198 aa)
initn: 1202 init1: 824 opt: 824 Z-score: 1042.0 bits: 199.6 E(85289): 2.6e-51
Smith-Waterman score: 1182; 93.9% identity (93.9% similar) in 198 aa overlap (1-186:1-198)
10 20 30 40 50 60
pF1KE5 MKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQGLYRGYKSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQGLYRGYKSTV
10 20 30 40 50 60
70 80 90 100
pF1KE5 LRE------------IPFSLVQFPLWESLKALWSWRQDHVVDSWQSAVCGAFAGGFAAAV
::: :::::::::::::::::::::::::::::::::::::::::::::
XP_016 LREGRNAGMGLLGHVIPFSLVQFPLWESLKALWSWRQDHVVDSWQSAVCGAFAGGFAAAV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE5 TTPLDVAKTRITLAKAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAISLGGFIFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTPLDVAKTRITLAKAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAISLGGFIFL
130 140 150 160 170 180
170 180
pF1KE5 GAYDRTHSLLLEVGRKSP
::::::::::::::::::
XP_016 GAYDRTHSLLLEVGRKSP
190
>>XP_016861162 (OMIM: 611037,616794) PREDICTED: S-adenos (198 aa)
initn: 1202 init1: 824 opt: 824 Z-score: 1042.0 bits: 199.6 E(85289): 2.6e-51
Smith-Waterman score: 1182; 93.9% identity (93.9% similar) in 198 aa overlap (1-186:1-198)
10 20 30 40 50 60
pF1KE5 MKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQGLYRGYKSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQGLYRGYKSTV
10 20 30 40 50 60
70 80 90 100
pF1KE5 LRE------------IPFSLVQFPLWESLKALWSWRQDHVVDSWQSAVCGAFAGGFAAAV
::: :::::::::::::::::::::::::::::::::::::::::::::
XP_016 LREGRNAGMGLLGHVIPFSLVQFPLWESLKALWSWRQDHVVDSWQSAVCGAFAGGFAAAV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE5 TTPLDVAKTRITLAKAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAISLGGFIFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTPLDVAKTRITLAKAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAISLGGFIFL
130 140 150 160 170 180
170 180
pF1KE5 GAYDRTHSLLLEVGRKSP
::::::::::::::::::
XP_016 GAYDRTHSLLLEVGRKSP
190
>>XP_016861160 (OMIM: 611037,616794) PREDICTED: S-adenos (286 aa)
initn: 1202 init1: 824 opt: 824 Z-score: 1039.9 bits: 199.7 E(85289): 3.5e-51
Smith-Waterman score: 1182; 93.9% identity (93.9% similar) in 198 aa overlap (1-186:89-286)
10 20 30
pF1KE5 MKHMLAASAGEVVACLIRVPSEVVKQRAQV
::::::::::::::::::::::::::::::
XP_016 GSFPNAAAFFITYEYVKWFLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVKQRAQV
60 70 80 90 100 110
40 50 60 70
pF1KE5 SASTRTFQIFSNILYEEGIQGLYRGYKSTVLRE------------IPFSLVQFPLWESLK
::::::::::::::::::::::::::::::::: :::::::::::::::
XP_016 SASTRTFQIFSNILYEEGIQGLYRGYKSTVLREGRNAGMGLLGHVIPFSLVQFPLWESLK
120 130 140 150 160 170
80 90 100 110 120 130
pF1KE5 ALWSWRQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRITLAKAGSSTADGNVLSVLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALWSWRQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRITLAKAGSSTADGNVLSVLH
180 190 200 210 220 230
140 150 160 170 180
pF1KE5 GVWRSQGLAGLFAGVFPRMAAISLGGFIFLGAYDRTHSLLLEVGRKSP
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVWRSQGLAGLFAGVFPRMAAISLGGFIFLGAYDRTHSLLLEVGRKSP
240 250 260 270 280
>>XP_016861163 (OMIM: 611037,616794) PREDICTED: S-adenos (171 aa)
initn: 720 init1: 720 opt: 720 Z-score: 912.6 bits: 175.4 E(85289): 4.3e-44
Smith-Waterman score: 1071; 91.9% identity (91.9% similar) in 186 aa overlap (1-186:1-171)
10 20 30 40 50 60
pF1KE5 MKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQGLYRGYKSTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFSNILYEEGIQGLYRGYKSTV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE5 LREIPFSLVQFPLWESLKALWSWRQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRIT
::: ::::::::::::::::::::::::::::::::::::::::::
XP_016 LRE---------------ALWSWRQDHVVDSWQSAVCGAFAGGFAAAVTTPLDVAKTRIT
70 80 90 100
130 140 150 160 170 180
pF1KE5 LAKAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAISLGGFIFLGAYDRTHSLLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAKAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAISLGGFIFLGAYDRTHSLLLE
110 120 130 140 150 160
pF1KE5 VGRKSP
::::::
XP_016 VGRKSP
170
>>XP_006713019 (OMIM: 611037,616794) PREDICTED: S-adenos (259 aa)
initn: 720 init1: 720 opt: 720 Z-score: 910.2 bits: 175.6 E(85289): 5.8e-44
Smith-Waterman score: 1071; 91.9% identity (91.9% similar) in 186 aa overlap (1-186:89-259)
10 20 30
pF1KE5 MKHMLAASAGEVVACLIRVPSEVVKQRAQV
::::::::::::::::::::::::::::::
XP_006 GSFPNAAAFFITYEYVKWFLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVKQRAQV
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE5 SASTRTFQIFSNILYEEGIQGLYRGYKSTVLREIPFSLVQFPLWESLKALWSWRQDHVVD
::::::::::::::::::::::::::::::::: ::::::::::::
XP_006 SASTRTFQIFSNILYEEGIQGLYRGYKSTVLRE---------------ALWSWRQDHVVD
120 130 140 150 160
100 110 120 130 140 150
pF1KE5 SWQSAVCGAFAGGFAAAVTTPLDVAKTRITLAKAGSSTADGNVLSVLHGVWRSQGLAGLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SWQSAVCGAFAGGFAAAVTTPLDVAKTRITLAKAGSSTADGNVLSVLHGVWRSQGLAGLF
170 180 190 200 210 220
160 170 180
pF1KE5 AGVFPRMAAISLGGFIFLGAYDRTHSLLLEVGRKSP
::::::::::::::::::::::::::::::::::::
XP_006 AGVFPRMAAISLGGFIFLGAYDRTHSLLLEVGRKSP
230 240 250
>>XP_011531630 (OMIM: 611037,616794) PREDICTED: S-adenos (162 aa)
initn: 397 init1: 397 opt: 407 Z-score: 520.8 bits: 102.8 E(85289): 2.9e-22
Smith-Waterman score: 407; 94.4% identity (97.2% similar) in 71 aa overlap (1-71:89-158)
10 20 30
pF1KE5 MKHMLAASAGEVVACLIRVPSEVVKQRAQV
::::::::::::::::::::::::::::::
XP_011 GSFPNAAAFFITYEYVKWFLHADSSSYLTPMKHMLAASAGEVVACLIRVPSEVVKQRAQV
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE5 SASTRTFQIFSNILYEEGIQGLYRGYKSTVLREIPFSLVQFPLWESLKALWSWRQDHVVD
:::::::::::::::::::::::::::::::::: ::..:
XP_011 SASTRTFQIFSNILYEEGIQGLYRGYKSTVLREIN-SLIEFFSKS
120 130 140 150 160
100 110 120 130 140 150
pF1KE5 SWQSAVCGAFAGGFAAAVTTPLDVAKTRITLAKAGSSTADGNVLSVLHGVWRSQGLAGLF
>>XP_011510372 (OMIM: 603667,612949) PREDICTED: calcium- (587 aa)
initn: 233 init1: 135 opt: 258 Z-score: 326.6 bits: 68.8 E(85289): 1.9e-11
Smith-Waterman score: 258; 37.6% identity (65.2% similar) in 141 aa overlap (20-157:355-493)
10 20 30 40
pF1KE5 MKHMLAASAGEVVACLIRVPSEVVKQRAQVSASTRTFQIFS--NILYEE
: :.:: : ::.. : : :.: .
XP_011 KFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDL
330 340 350 360 370 380
50 60 70 80 90 100
pF1KE5 GIQGLYRGYKSTVLREIPFSLVQFPLWESLKALWSWRQDHVVDSWQSAVCGAFAGGFAAA
:: :::.: :. ::.:::: . ::.. : : . .. :: . . . ::.:: ::.
XP_011 GIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHV-GGLNLLAAGAMAGVPAAS
390 400 410 420 430 440
110 120 130 140 150 160
pF1KE5 VTTPLDVAKTRITLA-KAGSSTADGNVLSVLHGVWRSQGLAGLFAGVFPRMAAISLGGFI
..:: :: :::. .: .::..: .: :.. .. . : .: .... :. :.
XP_011 LVTPADVIKTRLQVAARAGQTTYSG-VIDCFRKILREEGPSAFWKGTAARVFRSSPQFGV
450 460 470 480 490 500
170 180
pF1KE5 FLGAYDRTHSLLLEVGRKSP
XP_011 TLVTYELLQRWFYIDFGGLKPAGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKF
510 520 530 540 550 560
186 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:58:37 2016 done: Mon Nov 7 22:58:38 2016
Total Scan time: 5.720 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]