Result of FASTA (ccds) for
pFN21AE6374
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6374, 439 aa
1>>>pF1KE6374 439 - 439 aa - 439 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5262+/-0.000863; mu= 16.8675+/- 0.052
mean_var=85.2541+/-16.766, 0's: 0 Z-trim(108.3): 59 B-trim: 3 in 1/51
Lambda= 0.138905
statistics sampled from 10073 (10132) to 10073 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.684), E-opt: 0.2 (0.311), width: 16
Scan time: 2.300
The best scores are: opt bits E(32554)
CCDS6485.1 ADAMTSL1 gene_id:92949|Hs108|chr9 ( 525) 2558 522.6 3.5e-148
CCDS47954.1 ADAMTSL1 gene_id:92949|Hs108|chr9 (1762) 2558 523.0 8.9e-148
CCDS73773.1 ADAMTSL3 gene_id:57188|Hs108|chr15 (1682) 1812 373.5 8.7e-103
CCDS10326.1 ADAMTSL3 gene_id:57188|Hs108|chr15 (1691) 1812 373.5 8.7e-103
CCDS12206.1 ADAMTS10 gene_id:81794|Hs108|chr19 (1103) 938 198.2 3.3e-50
CCDS43299.1 ADAMTS16 gene_id:170690|Hs108|chr5 (1224) 757 162.0 3e-39
CCDS34140.1 ADAMTS12 gene_id:81792|Hs108|chr5 (1594) 660 142.6 2.6e-33
CCDS32303.1 ADAMTS7 gene_id:11173|Hs108|chr15 (1686) 658 142.3 3.6e-33
CCDS3983.2 ADAMTS6 gene_id:11174|Hs108|chr5 (1117) 654 141.3 4.6e-33
CCDS62529.1 ADAMTS10 gene_id:81794|Hs108|chr19 ( 590) 641 138.5 1.7e-32
CCDS10926.1 ADAMTS18 gene_id:170692|Hs108|chr16 (1221) 617 133.9 8.3e-31
CCDS4146.1 ADAMTS19 gene_id:171019|Hs108|chr5 (1207) 572 124.9 4.3e-28
CCDS12071.1 ADAMTSL5 gene_id:339366|Hs108|chr19 ( 471) 539 118.0 2e-26
CCDS30852.1 ADAMTSL4 gene_id:54507|Hs108|chr1 ( 877) 538 118.0 3.8e-26
CCDS955.1 ADAMTSL4 gene_id:54507|Hs108|chr1 (1074) 538 118.1 4.4e-26
CCDS32114.1 PAPLN gene_id:89932|Hs108|chr14 (1251) 535 117.5 7.5e-26
CCDS10383.1 ADAMTS17 gene_id:170691|Hs108|chr15 (1095) 516 113.7 9.5e-25
CCDS33524.1 ADAMTS1 gene_id:9510|Hs108|chr21 ( 967) 462 102.8 1.6e-21
CCDS1223.1 ADAMTS4 gene_id:9507|Hs108|chr1 ( 837) 457 101.8 2.8e-21
CCDS13579.1 ADAMTS5 gene_id:11096|Hs108|chr21 ( 930) 451 100.6 7e-21
CCDS4444.1 ADAMTS2 gene_id:9509|Hs108|chr5 (1211) 449 100.3 1.1e-20
CCDS7306.1 ADAMTS14 gene_id:140766|Hs108|chr10 (1223) 438 98.1 5.2e-20
CCDS7307.1 ADAMTS14 gene_id:140766|Hs108|chr10 (1226) 438 98.1 5.3e-20
CCDS31778.2 ADAMTS20 gene_id:80070|Hs108|chr12 (1910) 439 98.4 6.4e-20
CCDS10238.2 THSD4 gene_id:79875|Hs108|chr15 (1018) 435 97.4 6.9e-20
CCDS8488.1 ADAMTS15 gene_id:170689|Hs108|chr11 ( 950) 432 96.8 9.9e-20
CCDS41732.1 ADAMTS8 gene_id:11095|Hs108|chr11 ( 889) 420 94.4 5e-19
CCDS82801.1 ADAMTS9 gene_id:56999|Hs108|chr3 (1907) 424 95.4 5.2e-19
CCDS2903.1 ADAMTS9 gene_id:56999|Hs108|chr3 (1935) 424 95.4 5.2e-19
CCDS72908.1 ADAMTSL4 gene_id:54507|Hs108|chr1 (1097) 410 92.4 2.4e-18
CCDS6976.1 ADAMTSL2 gene_id:9719|Hs108|chr9 ( 951) 397 89.8 1.3e-17
CCDS66817.1 THSD4 gene_id:79875|Hs108|chr15 ( 658) 325 75.2 2.1e-13
>>CCDS6485.1 ADAMTSL1 gene_id:92949|Hs108|chr9 (525 aa)
initn: 3082 init1: 2558 opt: 2558 Z-score: 2773.7 bits: 522.6 E(32554): 3.5e-148
Smith-Waterman score: 3052; 96.0% identity (96.0% similar) in 450 aa overlap (1-433:1-450)
10 20 30 40 50 60
pF1KE6 MECCRRATPGTLLLFLAFLLLSSRTARSEEDRDGLWDAWGPWSECSRTCGGGASYSLRRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 MECCRRATPGTLLLFLAFLLLSSRTARSEEDRDGLWDAWGPWSECSRTCGGGASYSLRRC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LSSKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDVKHHGQFYEWLPVSNDPDNPCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 LSSKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDVKHHGQFYEWLPVSNDPDNPCS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LKCQAKGTTLVVELAPKVLDGTRCYTESLDMCISGLCQIVGCDHQLGSTVKEDNCGVCNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 LKCQAKGTTLVVELAPKVLDGTRCYTESLDMCISGLCQIVGCDHQLGSTVKEDNCGVCNG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DGSTCRLVRGQYKSQLSATKSDDTVVAIPYGSRHIRLVLKGPDHLYLETKTLQGTKGENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 DGSTCRLVRGQYKSQLSATKSDDTVVAIPYGSRHIRLVLKGPDHLYLETKTLQGTKGENS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 LSSTGTFLVDNSSVDFQKFPDKEILRMAGPLTADFIVKIRNSGSADSTVQFIFYQPIIHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 LSSTGTFLVDNSSVDFQKFPDKEILRMAGPLTADFIVKIRNSGSADSTVQFIFYQPIIHR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 WRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 WRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPCP
310 320 330 340 350 360
370 380 390 400
pF1KE6 A-----------------RWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWKC
: ::::::::::::::::::::::::::::::::::::::::::
CCDS64 ASDGYKQIMPYDLYHPLPRWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWKC
370 380 390 400 410 420
410 420 430
pF1KE6 MYTPKMPIAQPCNIFDCPKWLAQEWSPVTVPSFFVH
::::::::::::::::::::::::::: ::
CCDS64 MYTPKMPIAQPCNIFDCPKWLAQEWSPCTVTCGQGLRYRVVLCIDHRGMHTGGCSPKTKP
430 440 450 460 470 480
>>CCDS47954.1 ADAMTSL1 gene_id:92949|Hs108|chr9 (1762 aa)
initn: 3082 init1: 2558 opt: 2558 Z-score: 2766.5 bits: 523.0 E(32554): 8.9e-148
Smith-Waterman score: 3052; 96.0% identity (96.0% similar) in 450 aa overlap (1-433:1-450)
10 20 30 40 50 60
pF1KE6 MECCRRATPGTLLLFLAFLLLSSRTARSEEDRDGLWDAWGPWSECSRTCGGGASYSLRRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 MECCRRATPGTLLLFLAFLLLSSRTARSEEDRDGLWDAWGPWSECSRTCGGGASYSLRRC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LSSKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDVKHHGQFYEWLPVSNDPDNPCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LSSKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDVKHHGQFYEWLPVSNDPDNPCS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LKCQAKGTTLVVELAPKVLDGTRCYTESLDMCISGLCQIVGCDHQLGSTVKEDNCGVCNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LKCQAKGTTLVVELAPKVLDGTRCYTESLDMCISGLCQIVGCDHQLGSTVKEDNCGVCNG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DGSTCRLVRGQYKSQLSATKSDDTVVAIPYGSRHIRLVLKGPDHLYLETKTLQGTKGENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 DGSTCRLVRGQYKSQLSATKSDDTVVAIPYGSRHIRLVLKGPDHLYLETKTLQGTKGENS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 LSSTGTFLVDNSSVDFQKFPDKEILRMAGPLTADFIVKIRNSGSADSTVQFIFYQPIIHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 LSSTGTFLVDNSSVDFQKFPDKEILRMAGPLTADFIVKIRNSGSADSTVQFIFYQPIIHR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 WRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPCP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS47 WRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPCP
310 320 330 340 350 360
370 380 390 400
pF1KE6 A-----------------RWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWKC
: ::::::::::::::::::::::::::::::::::::::::::
CCDS47 ASDGYKQIMPYDLYHPLPRWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWKC
370 380 390 400 410 420
410 420 430
pF1KE6 MYTPKMPIAQPCNIFDCPKWLAQEWSPVTVPSFFVH
::::::::::::::::::::::::::: ::
CCDS47 MYTPKMPIAQPCNIFDCPKWLAQEWSPCTVTCGQGLRYRVVLCIDHRGMHTGGCSPKTKP
430 440 450 460 470 480
>>CCDS73773.1 ADAMTSL3 gene_id:57188|Hs108|chr15 (1682 aa)
initn: 2181 init1: 1806 opt: 1812 Z-score: 1958.8 bits: 373.5 E(32554): 8.7e-103
Smith-Waterman score: 2157; 63.4% identity (84.0% similar) in 443 aa overlap (8-433:50-492)
10 20 30
pF1KE6 MECCRRATPGTLLLFLAFLLLSSRTARSEEDRDGLWD
: : .: . .::..::.::.:: ::
CCDS73 PLPQTTAEKSPGAYFLPEFALSPQGSFLEDTTGEQFLTYRYDDQTSRNTRSDEDKDGNWD
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE6 AWGPWSECSRTCGGGASYSLRRCLSSKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHN
::: ::.:::::::::::::::::....:::.::::.:::: ::::.: :::::::::.:
CCDS73 AWGDWSDCSRTCGGGASYSLRRCLTGRNCEGQNIRYKTCSNHDCPPDAEDFRAQQCSAYN
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE6 DVKHHGQFYEWLPVSNDPDNPCSLKCQAKGTTLVVELAPKVLDGTRCYTESLDMCISGLC
::...:..::::: ::: ::.:::.:.: .::::::::::::::: :.::::::::.:
CCDS73 DVQYQGHYYEWLPRYNDPAAPCALKCHAQGQNLVVELAPKVLDGTRCNTDSLDMCISGIC
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE6 QIVGCDHQLGSTVKEDNCGVCNGDGSTCRLVRGQYKSQLSATKSDDTVVAIPYGSRHIRL
: ::::.::::..:::::::: :::::::::::: ::..: : ...:.:.: ::: .:.
CCDS73 QAVGCDRQLGSNAKEDNCGVCAGDGSTCRLVRGQSKSHVSPEKREENVIAVPLGSRSVRI
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE6 VLKGPDHLYLETKTLQGTKGENSLSSTGTFLVDNSSVDFQKFPDKEILRMAGPLTADFIV
..::: ::..:.:::::.:::.:..: :.:::.:..:.::. ... ... ::: ::::
CCDS73 TVKGPAHLFIESKTLQGSKGEHSFNSPGVFLVENTTVEFQRGSERQTFKIPGPLMADFIF
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE6 KIRNSGSADSTVQFIFYQPIIHRWRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQY
: : ... ::.:::.::::: :.::.::::::..::::::::.:::: :.: .::: :.:
CCDS73 KTRYTAAKDSVVQFFFYQPISHQWRQTDFFPCTVTCGGGYQLNSAECVDIRLKRVVPDHY
320 330 340 350 360 370
340 350 360 370 380
pF1KE6 CHYYPENIKPKPKLQECNLDPCPA-----------------RWEATPWTACSSSCGGGIQ
:::::::.::::::.::..::::. ::: .:::::: :::::::
CCDS73 CHYYPENVKPKPKLKECSMDPCPSSDGFKEIMPYDHFQPLPRWEHNPWTACSVSCGGGIQ
380 390 400 410 420 430
390 400 410 420 430
pF1KE6 SRAVSCVEEDIQGHVTSVEEWKCMYTPKMPIAQPCNIFDCPKWLAQEWSPVTVPSFFVH
:. ::::...:.. .::::::::.:: . : ::.::::::.:.::: ::
CCDS73 RRSFVCVEESMHGEILQVEEWKCMYAPKPKVMQTCNLFDCPKWIAMEWSQCTVTCGRGLR
440 450 460 470 480 490
CCDS73 YRVVLCINHRGEHVGGCNPQLKLHIKEECVIPIPCYKPKEKSPVEAKLPWLKQAQELEET
500 510 520 530 540 550
>>CCDS10326.1 ADAMTSL3 gene_id:57188|Hs108|chr15 (1691 aa)
initn: 2181 init1: 1806 opt: 1812 Z-score: 1958.8 bits: 373.5 E(32554): 8.7e-103
Smith-Waterman score: 2157; 63.4% identity (84.0% similar) in 443 aa overlap (8-433:50-492)
10 20 30
pF1KE6 MECCRRATPGTLLLFLAFLLLSSRTARSEEDRDGLWD
: : .: . .::..::.::.:: ::
CCDS10 PLPQTTAEKSPGAYFLPEFALSPQGSFLEDTTGEQFLTYRYDDQTSRNTRSDEDKDGNWD
20 30 40 50 60 70
40 50 60 70 80 90
pF1KE6 AWGPWSECSRTCGGGASYSLRRCLSSKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHN
::: ::.:::::::::::::::::....:::.::::.:::: ::::.: :::::::::.:
CCDS10 AWGDWSDCSRTCGGGASYSLRRCLTGRNCEGQNIRYKTCSNHDCPPDAEDFRAQQCSAYN
80 90 100 110 120 130
100 110 120 130 140 150
pF1KE6 DVKHHGQFYEWLPVSNDPDNPCSLKCQAKGTTLVVELAPKVLDGTRCYTESLDMCISGLC
::...:..::::: ::: ::.:::.:.: .::::::::::::::: :.::::::::.:
CCDS10 DVQYQGHYYEWLPRYNDPAAPCALKCHAQGQNLVVELAPKVLDGTRCNTDSLDMCISGIC
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE6 QIVGCDHQLGSTVKEDNCGVCNGDGSTCRLVRGQYKSQLSATKSDDTVVAIPYGSRHIRL
: ::::.::::..:::::::: :::::::::::: ::..: : ...:.:.: ::: .:.
CCDS10 QAVGCDRQLGSNAKEDNCGVCAGDGSTCRLVRGQSKSHVSPEKREENVIAVPLGSRSVRI
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE6 VLKGPDHLYLETKTLQGTKGENSLSSTGTFLVDNSSVDFQKFPDKEILRMAGPLTADFIV
..::: ::..:.:::::.:::.:..: :.:::.:..:.::. ... ... ::: ::::
CCDS10 TVKGPAHLFIESKTLQGSKGEHSFNSPGVFLVENTTVEFQRGSERQTFKIPGPLMADFIF
260 270 280 290 300 310
280 290 300 310 320 330
pF1KE6 KIRNSGSADSTVQFIFYQPIIHRWRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQY
: : ... ::.:::.::::: :.::.::::::..::::::::.:::: :.: .::: :.:
CCDS10 KTRYTAAKDSVVQFFFYQPISHQWRQTDFFPCTVTCGGGYQLNSAECVDIRLKRVVPDHY
320 330 340 350 360 370
340 350 360 370 380
pF1KE6 CHYYPENIKPKPKLQECNLDPCPA-----------------RWEATPWTACSSSCGGGIQ
:::::::.::::::.::..::::. ::: .:::::: :::::::
CCDS10 CHYYPENVKPKPKLKECSMDPCPSSDGFKEIMPYDHFQPLPRWEHNPWTACSVSCGGGIQ
380 390 400 410 420 430
390 400 410 420 430
pF1KE6 SRAVSCVEEDIQGHVTSVEEWKCMYTPKMPIAQPCNIFDCPKWLAQEWSPVTVPSFFVH
:. ::::...:.. .::::::::.:: . : ::.::::::.:.::: ::
CCDS10 RRSFVCVEESMHGEILQVEEWKCMYAPKPKVMQTCNLFDCPKWIAMEWSQCTVTCGRGLR
440 450 460 470 480 490
CCDS10 YRVVLCINHRGEHVGGCNPQLKLHIKEECVIPIPCYKPKEKSPVEAKLPWLKQAQELEET
500 510 520 530 540 550
>>CCDS12206.1 ADAMTS10 gene_id:81794|Hs108|chr19 (1103 aa)
initn: 851 init1: 431 opt: 938 Z-score: 1014.8 bits: 198.2 E(32554): 3.3e-50
Smith-Waterman score: 953; 35.6% identity (60.2% similar) in 430 aa overlap (30-435:544-959)
10 20 30 40 50
pF1KE6 MECCRRATPGTLLLFLAFLLLSSRTARSEEDRDGLWDAWGPWSECSRTCGGGASYSLRR
: :: : : ::..::::::::.: : :.
CCDS12 PAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRH
520 530 540 550 560 570
60 70 80 90 100 110
pF1KE6 C------LSSKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDVKHHGQFYEWLPVSN
: ...: : :. :.:.:.. :::: . ::: ::: ... .:.::.: .
CCDS12 CDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREVQCSEFDSIPFRGKFYKWKTYRG
580 590 600 610 620 630
120 130 140 150 160 170
pF1KE6 DPDNPCSLKCQAKGTTLVVELAPKVLDGTRCYTESLDMCISGLCQIVGCDHQLGSTVKED
. ::: : :.: .. .: : :.::: : ...:.:.:: :. ::::. ::: ..::
CCDS12 GGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLRED
640 650 660 670 680 690
180 190 200 210 220
pF1KE6 NCGVCNGDGSTCRLVRGQYKSQLSATKSDDTVVAIPYGSRHI----------RLVLKGPD
.: ::.::::.:. ..: . : : . . :: :: :: :: .:.::: :
CCDS12 KCRVCGGDGSACETIEGVF-SPASPGAGYEDVVWIPKGSVHIFIQDLNLSLSHLALKG-D
700 710 720 730 740 750
230 240 250 260 270 280
pF1KE6 HLYLETKTLQGTKGENSLSSTGTFLVDNSSVDFQKFPDK-EILRMAGPLTADFIVKIRNS
. : . : :: . : .:: . .... ::. . :. ::..:..:: .
CCDS12 QESLLLEGLPGTPQPHRLPLAGT------TFQLRQGPDQVQSLEALGPINASLIVMVLAR
760 770 780 790 800
290 300 310 320 330
pF1KE6 GSADSTVQFIFYQPII------HRWRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQ
. .... : :: . :. . . ::: :.:: :. ..:: . .. .:: .
CCDS12 -TELPALRYRFNAPIARDSLPPYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPH
810 820 830 840 850 860
340 350 360 370 380 390
pF1KE6 YCHYYPENIKPKPKLQECNLDPCPARWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVT
:: . . :: . . :: .::: : . :. :: :: .:..::.: : .. ..
CCDS12 YCSAHSK--LPK-RQRACNTEPCPPDWVVGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEK
870 880 890 900 910 920
400 410 420 430
pF1KE6 SVEEWKCMYTPKMPIAQPCNIFDCP-KWLAQEWSPVTVPSFFVH
.... : :. :. . :. :: .: : .:: : ::
CCDS12 ALDDSACPQ-PRPPVLEACHGPTCPPEWAALDWSECT-PSCGPGLRHRVVLCKSADHRAT
930 940 950 960 970
CCDS12 LPPAHCSPAAKPPATMRCNLRRCPPARWVAGEWGECSAQCGVGQRQRSVRCTSHTGQASH
980 990 1000 1010 1020 1030
>>CCDS43299.1 ADAMTS16 gene_id:170690|Hs108|chr5 (1224 aa)
initn: 693 init1: 231 opt: 757 Z-score: 818.1 bits: 162.0 E(32554): 3e-39
Smith-Waterman score: 823; 33.6% identity (58.1% similar) in 420 aa overlap (34-429:587-996)
10 20 30 40 50 60
pF1KE6 CRRATPGTLLLFLAFLLLSSRTARSEEDRDGLWDAWGPWSECSRTCGGGASYSLRRCLSS
: :. :. :: ::::::::.:. : : .
CCDS43 AAEGTICGHDMWCRGGQCVKYGDEGPKPTHGHWSDWSSWSPCSRTCGGGVSHRSRLCTNP
560 570 580 590 600 610
70 80 90 100 110
pF1KE6 KS------CEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDVKHHGQFYEWLPVSNDPDN
: ::: . . :.. :: .. :::: ::. ::. . .:. :.: : .. :.
CCDS43 KPSHGGKFCEGSTRTLKLCNSQKCPRDSVDFRAAQCAEHNSRRFRGRHYKWKPYTQVEDQ
620 630 640 650 660 670
120 130 140 150 160 170
pF1KE6 P-CSLKCQAKGTTLVVELAPKVLDGTRCYTESLDMCISGLCQIVGCDHQLGSTVKEDNCG
:.: : :.: . :. :: ::: : .: ..::.:.:. ::::. ::: . :: ::
CCDS43 DLCKLYCIAEGFDFFFSLSNKVKDGTPCSEDSRNVCIDGICERVGCDNVLGSDAVEDVCG
680 690 700 710 720 730
180 190 200 210 220 230
pF1KE6 VCNGDGSTCRLVRGQYKSQLSATKSDDTVVAIPYGSRHIRLVLKGPDHLYLETKTL---Q
::::..:.: . :: : .. :.. .:.:: :.: ::. . . :. ...
CCDS43 VCNGNNSACTIHRGLY-TKHHHTNQYYHMVTIPSGARSIRIYEMNVSTSYISVRNALRRY
740 750 760 770 780 790
240 250 260 270 280 290
pF1KE6 GTKGENSLSSTGTFLVDNSSVDFQK-FPDKEILRMAGPLTADFIVKIRNSGSADSTVQFI
.:. ... : . .... :... . . : : .:: . .::.. .: . : .
CCDS43 YLNGHWTVDWPGRYKFSGTTFDYRRSYNEPENLIATGPTNETLIVELLFQGR-NPGVAWE
800 810 820 830 840 850
300 310 320 330 340
pF1KE6 FYQPIIHRWRETDFFP----------CSATCGGGYQLTSAE-CY-DLRSNRVVADQYCHY
. .: . .. : ::..:::: :.: : :: ::. . : ..:.
CCDS43 YSMPRLGTEKQPPAQPSYTWAIVRSECSVSCGGG-QMTVREGCYRDLKFQ--VNMSFCN-
860 870 880 890 900 910
350 360 370 380 390 400
pF1KE6 YPENIKPKPKLQECNLDPCPARWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEE
:.. .: : :... :: : . :.::: .:::: ::: :.:... .. :
CCDS43 -PKT-RPVTGLVPCKVSACPPSWSVGNWSACSRTCGGGAQSRPVQCTRR-VHYDSEPVPA
920 930 940 950 960
410 420 430
pF1KE6 WKCMYTPKMPIAQPCNIFDCPK-WLAQEWSPVTVPSFFVH
: : : :: .:: : : :.
CCDS43 SLCPQ-PAPSSRQACNSQSCPPAWSAGPWAECSHTCGKGWRKRAVACKSTNPSARAQLLP
970 980 990 1000 1010 1020
>>CCDS34140.1 ADAMTS12 gene_id:81792|Hs108|chr5 (1594 aa)
initn: 530 init1: 208 opt: 660 Z-score: 711.5 bits: 142.6 E(32554): 2.6e-33
Smith-Waterman score: 787; 30.6% identity (59.7% similar) in 434 aa overlap (27-433:536-958)
10 20 30 40 50
pF1KE6 MECCRRATPGTLLLFLAFLLLSSRTARSEEDRDGLWDAWGPWSECSRTCGGGASYS
.. :. : : :.:::.::::::.:.. .
CCDS34 FCRSKLDAAADGTQCGEKKWCMAGKCITVGKKPESIPGGWGRWSPWSHCSRTCGAGVQSA
510 520 530 540 550 560
60 70 80 90 100 110
pF1KE6 LRRC------LSSKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDVKHHGQFYEWLP
: : ...: : :. ::: :. : :: :: .::: . : .....:.:.:
CCDS34 ERLCNNPEPKFGGKYCTGERKRYRLCNVHPCRSEAPTFRQMQCSEFDTVPYKNELYHWFP
570 580 590 600 610 620
120 130 140 150 160
pF1KE6 VSNDPDNPCSLKCQAKGTTLVVELAPKVLDGTRCYT--ESLDMCISGLCQIVGCDHQLGS
. : : .:: : :. . .. :.::: :. .: ..::.:.:..::::... :
CCDS34 IFN-PAHPCELYCRPIDGQFSEKMLDAVIDGTPCFEGGNSRNVCINGICKMVGCDYEIDS
630 640 650 660 670 680
170 180 190 200 210 220
pF1KE6 TVKEDNCGVCNGDGSTCRLVRGQYKSQLSATKSDDTVVAIPYGSRHIRLV-LKGPDHLYL
.. :: :::: ::::.:. :: ..:.. .. : . :: :.: ::.. ..: . .:
CCDS34 NATEDRCGVCLGDGSSCQTVRKMFKQKEGSGYVD--IGLIPKGARDIRVMEIEGAGN-FL
690 700 710 720 730 740
230 240 250 260 270
pF1KE6 ETKTLQGTK----GENSLSSTGTFLVDNSSVDFQKFPDKEILRMAGPLTAD----FIVKI
.. . : : .. .:.. . .. .... : : : .:: . . .. ..
CCDS34 AIRSEDPEKYYLNGGFIIQWNGNYKLAGTVFQYDRKGDLEKLMATGPTNESVWIQLLFQV
750 760 770 780 790 800
280 290 300 310 320 330
pF1KE6 RNSG-SADSTVQFIFYQPIIHR----WRETDFFPCSATCGGGYQLTSAECYDLRSNR-VV
: : . . :.: . ... :. . ::.::: : . .:.: ....: .:
CCDS34 TNPGIKYEYTIQKDGLDNDVEQQMYFWQYGHWTECSVTCGTGIRRQTAHC--IKKGRGMV
810 820 830 840 850
340 350 360 370 380 390
pF1KE6 ADQYCHYYPENIKPKPKLQECNLDPCPARWEATPWTACSSSCGG-GIQSRAVSCVEEDIQ
.: ::. .:. . ..:. :: :: : : :::..:: : ..:.: :.. ..
CCDS34 KATFCD--PET-QPNGRQKKCHEKACPPRWWAGEWEACSATCGPHGEKKRTVLCIQTMVS
860 870 880 890 900 910
400 410 420 430
pF1KE6 GHVTSVEEWKCMYTPKMPIAQPCN--IFDCPK-WLAQEWSPVTVPSFFVH
. .. :.. : :: :. ::. : . .:: .:
CCDS34 DE-QALPPTDCQHLLKPKTLLSCNRDIL-CPSDWTVGNWSECSVSCGGGVRIRSVTCAKN
920 930 940 950 960 970
CCDS34 HDEPCDVTRKPNSRALCGLQQCPSSRRVLKPNKGTISNGKNPPTLKPVPPPTSRPRMLTT
980 990 1000 1010 1020 1030
>>CCDS32303.1 ADAMTS7 gene_id:11173|Hs108|chr15 (1686 aa)
initn: 606 init1: 187 opt: 658 Z-score: 709.0 bits: 142.3 E(32554): 3.6e-33
Smith-Waterman score: 832; 31.9% identity (56.9% similar) in 429 aa overlap (30-433:535-956)
10 20 30 40 50
pF1KE6 MECCRRATPGTLLLFLAFLLLSSRTARSEEDRDGLWDAWGPWSECSRTCGGGASYSLRR
: :: :..:. :: :::.:: :.. . :.
CCDS32 SKLDAAVDGTRCGENKWCLSGECVPVGFRPEAVDGGWSGWSAWSICSRSCGMGVQSAERQ
510 520 530 540 550 560
60 70 80 90 100 110
pF1KE6 CLS------SKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDVKHHGQFYEWLPVSN
: . .. : :. :.: :. :: .:: ::: . . ..::.. :.:: :
CCDS32 CTQPTPKYKGRYCVGERKRFRLCNLQACPAGRPSFRHVQCSHFDAMLYKGQLHTWVPVVN
570 580 590 600 610 620
120 130 140 150 160 170
pF1KE6 DPDNPCSLKCQAKGTTLVVELAPKVLDGTRCYT--ESLDMCISGLCQIVGCDHQLGSTVK
: ::: :.:. . .. .: :.::: :: : :.::.:.:. :::: .. : .
CCDS32 DV-NPCELHCRPANEYFAEKLRDAVVDGTPCYQVRASRDLCINGICKNVGCDFEIDSGAM
630 640 650 660 670 680
180 190 200 210 220
pF1KE6 EDNCGVCNGDGSTCRLVRGQYKSQLSATKSDDTVVAIPYGSRHIRL--VLKGPDHLYLET
:: ::::.:.::::. : : .. . : : :: :.:.::. : .. . : :..
CCDS32 EDRCGVCHGNGSTCHTVSGTFEEAEGLGYVD--VGLIPAGAREIRIQEVAEAANFLALRS
690 700 710 720 730 740
230 240 250 260 270 280
pF1KE6 KTLQG--TKGENSLSSTGTFLVDNSSVDFQKFPDKEILRMAGPLTADFIVKIRNSGSADS
. . .: ... .: . : ... . . . : : :: ... . : .
CCDS32 EDPEKYFLNGGWTIQWNGDYQVAGTTFTYARRGNWENLTSPGPTKEPVWIQLLFQESNPG
750 760 770 780 790 800
290 300 310 320 330
pF1KE6 T-VQFIFYQ---------PIIHRWRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQY
. .. ... : . :. . :..::: : : .. : . :. : ...
CCDS32 VHYEYTIHREAGGHDEVPPPVFSWHYGPWTKCTVTCGRGVQRQNVYCLE-RQAGPVDEEH
810 820 830 840 850 860
340 350 360 370 380 390
pF1KE6 CHYYPENIKPKPKLQECNLDPCPARWEATPWTACSSSCG-GGIQSRAVSCVEEDIQGHVT
: : . .: . ..:. .:::::: : : :::::: ::.. ::: :.. . .
CCDS32 CD--PLG-RPDDQQRKCSEQPCPARWWAGEWQLCSSSCGPGGLSRRAVLCIRSVGLDEQS
870 880 890 900 910
400 410 420 430
pF1KE6 SVEEWKCMYTPKMPIAQPCNIF-DCPK-WLAQEWSPVTVPSFFVH
..: : . :. : ::: :: : . .:: .:
CCDS32 ALEPPACEHLPRPPTETPCNRHVPCPATWAVGNWSQCSVTCGEGTQRRNVLCTNDTGVPC
920 930 940 950 960 970
CCDS32 DEAQQPASEVTCSLPLCRWPLGTLGPEGSGSGSSSHELFNEADFIPHHLAPRPSPASSPK
980 990 1000 1010 1020 1030
>>CCDS3983.2 ADAMTS6 gene_id:11174|Hs108|chr5 (1117 aa)
initn: 888 init1: 467 opt: 654 Z-score: 707.1 bits: 141.3 E(32554): 4.6e-33
Smith-Waterman score: 961; 35.9% identity (60.6% similar) in 437 aa overlap (33-436:558-979)
10 20 30 40 50 60
pF1KE6 CCRRATPGTLLLFLAFLLLSSRTARSEEDRDGLWDAWGPWSECSRTCGGGASYSLRRCLS
:: : :. :.:::::::::.: :::.: :
CCDS39 EGTLCQTGNIEKGWCYQGDCVPFGTWPQSIDGGWGPWSLWGECSRTCGGGVSSSLRHCDS
530 540 550 560 570 580
70 80 90 100 110
pF1KE6 ------SKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDVKHHGQFYEWLPVSNDPD
.: : :. :::.:.. :: . ::: .::. ... .:..:.: : ..
CCDS39 PAPSGGGKYCLGERKRYRSCNTDPCPLGSRDFREKQCADFDNMPFRGKYYNWKPYTGGGV
590 600 610 620 630 640
120 130 140 150 160 170
pF1KE6 NPCSLKCQAKGTTLVVELAPKVLDGTRCYTESLDMCISGLCQIVGCDHQLGSTVKEDNCG
.::.:.: :.: .. .: :: :.:::.: ..:::.::.: :. ::::. ::: ..:: :
CCDS39 KPCALNCLAEGYNFYTERAPAVIDGTQCNADSLDICINGECKHVGCDNILGSDAREDRCR
650 660 670 680 690 700
180 190 200 210 220 230
pF1KE6 VCNGDGSTCRLVRGQYKSQLSATKSDDTVVAIPYGSRHI--RLVLKGPDHLYLETKTLQG
::.:::::: ..: ....: . :: :: :: :: : : . ... :... .
CCDS39 VCGGDGSTCDAIEGFFNDSLPRGGYME-VVQIPRGSVHIEVREVAMSKNYIALKSEGDDY
710 720 730 740 750 760
240 250 260 270
pF1KE6 -TKGENSLSSTGTFLVDNSSVDFQKFPDK-EILRMAGPLTADFIV---------------
.: ... : : ... ... :. : :. :: . ..::
CCDS39 YINGAWTIDWPRKFDVAGTAFHYKRPTDEPESLEALGPTSENLIVMVLLQEQNLGIRYKF
770 780 790 800 810 820
280 290 300 310 320 330
pF1KE6 --KIRNSGSADSTVQFIF-YQPIIHRWRETDFFPCSATCGGGYQLTSAECYDLRSNRVVA
: .::.:. : : . .:: : : :::::.:: : . : : .: .:
CCDS39 NVPITRTGSGDNEVGFTWNHQP----WSE-----CSATCAGGVQRQEVVCKRLDDNSIVQ
830 840 850 860 870
340 350 360 370 380 390
pF1KE6 DQYCHYYPENIKPKPKLQECNLDPCPARWEATPWTACSSSCGGGIQSRAVSCVEEDIQGH
..:: :.. :: . . :: .::: .: : ::..: ::...::: :... ..
CCDS39 NNYCD--PDS-KPPENQRACNTEPCPPEWFIGDWLECSKTCDGGMRTRAVLCIRKIGPSE
880 890 900 910 920 930
400 410 420 430
pF1KE6 VTSVEEWKCMYTPKMPIAQ-PCNIFDCP-KWLAQEWS---PVTVPSFFVH
... :. . :. . ::: .:: .:.: .:: : :.:
CCDS39 EETLDYSGCL--THRPVEKEPCNNQSCPPQWVALDWSECTPKCGPGFKHRIVLCKSSDLS
940 950 960 970 980 990
CCDS39 KTFPAAQCPEESKPPVRIRCSLGRCPPPRWVTGDWGQCSAQCGLGQQMRTVQCLSYTGQA
1000 1010 1020 1030 1040 1050
>>CCDS62529.1 ADAMTS10 gene_id:81794|Hs108|chr19 (590 aa)
initn: 564 init1: 292 opt: 641 Z-score: 696.9 bits: 138.5 E(32554): 1.7e-32
Smith-Waterman score: 656; 34.0% identity (59.4% similar) in 335 aa overlap (119-435:126-446)
90 100 110 120 130 140
pF1KE6 RAQQCSAHNDVKHHGQFYEWLPVSNDPDNPCSLKCQAKGTTLVVELAPKVLDGTRCYTES
::: : :.: .. .: : :.::: : ..
CCDS62 PRTSEKCSVLNLTASLSVGNSTSGKRTGEACSLTCLAEGFNFYTERAAAVVDGTPCRPDT
100 110 120 130 140 150
150 160 170 180 190 200
pF1KE6 LDMCISGLCQIVGCDHQLGSTVKEDNCGVCNGDGSTCRLVRGQYKSQLSATKSDDTVVAI
.:.:.:: :. ::::. ::: ..::.: ::.::::.:. ..: . : : . . :: :
CCDS62 VDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVF-SPASPGAGYEDVVWI
160 170 180 190 200 210
210 220 230 240 250
pF1KE6 PYGSRHI----------RLVLKGPDHLYLETKTLQGTKGENSLSSTGTFLVDNSSVDFQK
: :: :: .:.::: :. : . : :: . : .:: . ....
CCDS62 PKGSVHIFIQDLNLSLSHLALKG-DQESLLLEGLPGTPQPHRLPLAGT------TFQLRQ
220 230 240 250 260
260 270 280 290 300 310
pF1KE6 FPDK-EILRMAGPLTADFIVKIRNSGSADSTVQFIFYQPII------HRWRETDFFPCSA
::. . :. ::..:..:: . . .... : :: . :. . . :::
CCDS62 GPDQVQSLEALGPINASLIVMVLAR-TELPALRYRFNAPIARDSLPPYSWHYAPWTKCSA
270 280 290 300 310 320
320 330 340 350 360 370
pF1KE6 TCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPCPARWEATPWTAC
:.:: :. ..:: . .. .:: .:: . . :: . . :: .::: : . :. :
CCDS62 QCAGGSQVQAVECRNQLDSSAVAPHYCSAHSK--LPK-RQRACNTEPCPPDWVVGNWSLC
330 340 350 360 370 380
380 390 400 410 420 430
pF1KE6 SSSCGGGIQSRAVSCVEEDIQGHVTSVEEWKCMYTPKMPIAQPCNIFDCP-KWLAQEWSP
: :: .:..::.: : .. .. .... : :. :. . :. :: .: : .::
CCDS62 SRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQ-PRPPVLEACHGPTCPPEWAALDWSE
390 400 410 420 430 440
pF1KE6 VTVPSFFVH
: ::
CCDS62 CT-PSCGPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCNLRRCPPARWVAGEWGE
450 460 470 480 490 500
439 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:42:06 2016 done: Tue Nov 8 12:42:07 2016
Total Scan time: 2.300 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]