Result of FASTA (omim) for
pFN21AE5184
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5184, 72 aa
1>>>pF1KE5184 72 - 72 aa - 72 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8463+/-0.000306; mu= 7.9915+/- 0.019
mean_var=42.1145+/- 8.501, 0's: 0 Z-trim(114.8): 35 B-trim: 0 in 0/51
Lambda= 0.197633
statistics sampled from 24808 (24855) to 24808 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.291), width: 16
Scan time: 2.830
The best scores are: opt bits E(85289)
NP_001269544 (OMIM: 607337) bestrophin-3 isoform 5 ( 72) 460 137.9 1.3e-33
NP_001269545 (OMIM: 607337) bestrophin-3 isoform 5 ( 72) 460 137.9 1.3e-33
XP_016874354 (OMIM: 607337) PREDICTED: bestrophin- ( 178) 460 138.0 3.2e-33
NP_001269543 (OMIM: 607337) bestrophin-3 isoform 4 ( 398) 340 103.8 1.4e-22
XP_006719319 (OMIM: 607337) PREDICTED: bestrophin- ( 410) 340 103.8 1.4e-22
NP_001269542 (OMIM: 607337) bestrophin-3 isoform 3 ( 562) 340 103.8 1.9e-22
XP_011536263 (OMIM: 607337) PREDICTED: bestrophin- ( 562) 340 103.8 1.9e-22
NP_116124 (OMIM: 607337) bestrophin-3 isoform 1 [H ( 668) 340 103.8 2.3e-22
XP_016856512 (OMIM: 607336) PREDICTED: bestrophin- ( 473) 248 77.6 1.3e-14
NP_695006 (OMIM: 607336) bestrophin-4 [Homo sapien ( 473) 248 77.6 1.3e-14
XP_016856511 (OMIM: 607336) PREDICTED: bestrophin- ( 473) 248 77.6 1.3e-14
XP_016856510 (OMIM: 607336) PREDICTED: bestrophin- ( 475) 248 77.6 1.3e-14
XP_016856509 (OMIM: 607336) PREDICTED: bestrophin- ( 475) 248 77.6 1.3e-14
XP_005260020 (OMIM: 607335) PREDICTED: bestrophin- ( 509) 248 77.6 1.4e-14
NP_060152 (OMIM: 607335) bestrophin-2 [Homo sapien ( 509) 248 77.6 1.4e-14
XP_005274278 (OMIM: 153700,193220,607854,611809,61 ( 270) 232 73.0 1.8e-13
XP_005274276 (OMIM: 153700,193220,607854,611809,61 ( 321) 232 73.0 2.1e-13
XP_016873719 (OMIM: 153700,193220,607854,611809,61 ( 329) 232 73.0 2.1e-13
XP_005274273 (OMIM: 153700,193220,607854,611809,61 ( 375) 232 73.0 2.4e-13
XP_016873718 (OMIM: 153700,193220,607854,611809,61 ( 435) 232 73.0 2.8e-13
XP_005274272 (OMIM: 153700,193220,607854,611809,61 ( 479) 232 73.0 3.1e-13
NP_001287715 (OMIM: 153700,193220,607854,611809,61 ( 498) 232 73.0 3.2e-13
NP_001287716 (OMIM: 153700,193220,607854,611809,61 ( 525) 232 73.0 3.3e-13
XP_016873717 (OMIM: 153700,193220,607854,611809,61 ( 558) 232 73.0 3.5e-13
NP_004174 (OMIM: 153700,193220,607854,611809,61319 ( 585) 232 73.0 3.7e-13
NP_001132915 (OMIM: 153700,193220,607854,611809,61 ( 604) 232 73.0 3.8e-13
XP_011543532 (OMIM: 153700,193220,607854,611809,61 ( 633) 232 73.0 4e-13
XP_011543531 (OMIM: 153700,193220,607854,611809,61 ( 664) 232 73.0 4.2e-13
XP_005274267 (OMIM: 153700,193220,607854,611809,61 ( 664) 232 73.0 4.2e-13
>>NP_001269544 (OMIM: 607337) bestrophin-3 isoform 5 [Ho (72 aa)
initn: 460 init1: 460 opt: 460 Z-score: 724.2 bits: 137.9 E(85289): 1.3e-33
Smith-Waterman score: 460; 100.0% identity (100.0% similar) in 72 aa overlap (1-72:1-72)
10 20 30 40 50 60
pF1KE5 MFLISSSVHGSDEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAERTGMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFLISSSVHGSDEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAERTGMK
10 20 30 40 50 60
70
pF1KE5 PILPSSFEMQSF
::::::::::::
NP_001 PILPSSFEMQSF
70
>>NP_001269545 (OMIM: 607337) bestrophin-3 isoform 5 [Ho (72 aa)
initn: 460 init1: 460 opt: 460 Z-score: 724.2 bits: 137.9 E(85289): 1.3e-33
Smith-Waterman score: 460; 100.0% identity (100.0% similar) in 72 aa overlap (1-72:1-72)
10 20 30 40 50 60
pF1KE5 MFLISSSVHGSDEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAERTGMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFLISSSVHGSDEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAERTGMK
10 20 30 40 50 60
70
pF1KE5 PILPSSFEMQSF
::::::::::::
NP_001 PILPSSFEMQSF
70
>>XP_016874354 (OMIM: 607337) PREDICTED: bestrophin-3 is (178 aa)
initn: 460 init1: 460 opt: 460 Z-score: 717.4 bits: 138.0 E(85289): 3.2e-33
Smith-Waterman score: 460; 100.0% identity (100.0% similar) in 72 aa overlap (1-72:107-178)
10 20 30
pF1KE5 MFLISSSVHGSDEHGRLLRRTLMRYVNLTS
::::::::::::::::::::::::::::::
XP_016 PVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDEHGRLLRRTLMRYVNLTS
80 90 100 110 120 130
40 50 60 70
pF1KE5 LLIFRSVSTAVYKRFPTMDHVVEAERTGMKPILPSSFEMQSF
::::::::::::::::::::::::::::::::::::::::::
XP_016 LLIFRSVSTAVYKRFPTMDHVVEAERTGMKPILPSSFEMQSF
140 150 160 170
>>NP_001269543 (OMIM: 607337) bestrophin-3 isoform 4 [Ho (398 aa)
initn: 340 init1: 340 opt: 340 Z-score: 526.5 bits: 103.8 E(85289): 1.4e-22
Smith-Waterman score: 340; 100.0% identity (100.0% similar) in 54 aa overlap (1-54:107-160)
10 20 30
pF1KE5 MFLISSSVHGSDEHGRLLRRTLMRYVNLTS
::::::::::::::::::::::::::::::
NP_001 PVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDEHGRLLRRTLMRYVNLTS
80 90 100 110 120 130
40 50 60 70
pF1KE5 LLIFRSVSTAVYKRFPTMDHVVEAERTGMKPILPSSFEMQSF
::::::::::::::::::::::::
NP_001 LLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHLKSPHLKYWVPFIWFGNLATKAR
140 150 160 170 180 190
>>XP_006719319 (OMIM: 607337) PREDICTED: bestrophin-3 is (410 aa)
initn: 340 init1: 340 opt: 340 Z-score: 526.3 bits: 103.8 E(85289): 1.4e-22
Smith-Waterman score: 340; 100.0% identity (100.0% similar) in 54 aa overlap (1-54:107-160)
10 20 30
pF1KE5 MFLISSSVHGSDEHGRLLRRTLMRYVNLTS
::::::::::::::::::::::::::::::
XP_006 PVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDEHGRLLRRTLMRYVNLTS
80 90 100 110 120 130
40 50 60 70
pF1KE5 LLIFRSVSTAVYKRFPTMDHVVEAERTGMKPILPSSFEMQSF
::::::::::::::::::::::::
XP_006 LLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHLKSPHLKYWVPFIWFGNLATKAR
140 150 160 170 180 190
>>NP_001269542 (OMIM: 607337) bestrophin-3 isoform 3 [Ho (562 aa)
initn: 340 init1: 340 opt: 340 Z-score: 523.9 bits: 103.8 E(85289): 1.9e-22
Smith-Waterman score: 340; 100.0% identity (100.0% similar) in 54 aa overlap (1-54:1-54)
10 20 30 40 50 60
pF1KE5 MFLISSSVHGSDEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAERTGMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFLISSSVHGSDEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTD
10 20 30 40 50 60
70
pF1KE5 PILPSSFEMQSF
NP_001 ERKLFNHLKSPHLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFG
70 80 90 100 110 120
>>XP_011536263 (OMIM: 607337) PREDICTED: bestrophin-3 is (562 aa)
initn: 340 init1: 340 opt: 340 Z-score: 523.9 bits: 103.8 E(85289): 1.9e-22
Smith-Waterman score: 340; 100.0% identity (100.0% similar) in 54 aa overlap (1-54:1-54)
10 20 30 40 50 60
pF1KE5 MFLISSSVHGSDEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAERTGMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFLISSSVHGSDEHGRLLRRTLMRYVNLTSLLIFRSVSTAVYKRFPTMDHVVEAGFMTTD
10 20 30 40 50 60
70
pF1KE5 PILPSSFEMQSF
XP_011 ERKLFNHLKSPHLKYWVPFIWFGNLATKARNEGRIRDSVDLQSLMTEMNRYRSWCSLLFG
70 80 90 100 110 120
>>NP_116124 (OMIM: 607337) bestrophin-3 isoform 1 [Homo (668 aa)
initn: 340 init1: 340 opt: 340 Z-score: 522.6 bits: 103.8 E(85289): 2.3e-22
Smith-Waterman score: 340; 100.0% identity (100.0% similar) in 54 aa overlap (1-54:107-160)
10 20 30
pF1KE5 MFLISSSVHGSDEHGRLLRRTLMRYVNLTS
::::::::::::::::::::::::::::::
NP_116 PVTFVLGFYVTLVVNRWWNQFVNLPWPDRLMFLISSSVHGSDEHGRLLRRTLMRYVNLTS
80 90 100 110 120 130
40 50 60 70
pF1KE5 LLIFRSVSTAVYKRFPTMDHVVEAERTGMKPILPSSFEMQSF
::::::::::::::::::::::::
NP_116 LLIFRSVSTAVYKRFPTMDHVVEAGFMTTDERKLFNHLKSPHLKYWVPFIWFGNLATKAR
140 150 160 170 180 190
>>XP_016856512 (OMIM: 607336) PREDICTED: bestrophin-4 is (473 aa)
initn: 258 init1: 242 opt: 248 Z-score: 383.5 bits: 77.6 E(85289): 1.3e-14
Smith-Waterman score: 248; 70.4% identity (92.6% similar) in 54 aa overlap (1-54:107-160)
10 20 30
pF1KE5 MFLISSSVHGSDEHGRLLRRTLMRYVNLTS
: .::.:::: :..::::::::.::.::.:
XP_016 PLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQRGRLLRRTLIRYANLAS
80 90 100 110 120 130
40 50 60 70
pF1KE5 LLIFRSVSTAVYKRFPTMDHVVEAERTGMKPILPSSFEMQSF
.:..::::: : ::::::.:::.:
XP_016 VLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESLKSDFNKYWVPCVWFTNLAAQAR
140 150 160 170 180 190
>>NP_695006 (OMIM: 607336) bestrophin-4 [Homo sapiens] (473 aa)
initn: 258 init1: 242 opt: 248 Z-score: 383.5 bits: 77.6 E(85289): 1.3e-14
Smith-Waterman score: 248; 70.4% identity (92.6% similar) in 54 aa overlap (1-54:107-160)
10 20 30
pF1KE5 MFLISSSVHGSDEHGRLLRRTLMRYVNLTS
: .::.:::: :..::::::::.::.::.:
NP_695 PLSFVLGFYVTLVVNRWWSQYTSIPLPDQLMCVISASVHGVDQRGRLLRRTLIRYANLAS
80 90 100 110 120 130
40 50 60 70
pF1KE5 LLIFRSVSTAVYKRFPTMDHVVEAERTGMKPILPSSFEMQSF
.:..::::: : ::::::.:::.:
NP_695 VLVLRSVSTRVLKRFPTMEHVVDAGFMSQEERKKFESLKSDFNKYWVPCVWFTNLAAQAR
140 150 160 170 180 190
72 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 22:22:50 2016 done: Mon Nov 7 22:22:51 2016
Total Scan time: 2.830 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]