Result of FASTA (ccds) for
pFN21AE1718
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1718, 224 aa
1>>>pF1KE1718 224 - 224 aa - 224 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4401+/-0.000908; mu= 12.2397+/- 0.054
mean_var=54.6415+/-11.305, 0's: 0 Z-trim(103.8): 21 B-trim: 0 in 0/48
Lambda= 0.173505
statistics sampled from 7588 (7602) to 7588 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.234), width: 16
Scan time: 2.010
The best scores are: opt bits E(32554)
CCDS30911.1 CRP gene_id:1401|Hs108|chr1 ( 224) 1502 384.1 3.9e-107
CCDS1186.1 APCS gene_id:325|Hs108|chr1 ( 223) 777 202.6 1.7e-52
CCDS32762.1 NPTX1 gene_id:4884|Hs108|chr17 ( 432) 304 84.3 1.4e-16
CCDS32362.1 PTX4 gene_id:390667|Hs108|chr16 ( 473) 289 80.5 2e-15
CCDS33647.1 NPTXR gene_id:23467|Hs108|chr22 ( 500) 281 78.5 8.4e-15
CCDS5657.1 NPTX2 gene_id:4885|Hs108|chr7 ( 431) 277 77.5 1.5e-14
CCDS48004.1 SVEP1 gene_id:79987|Hs108|chr9 (3571) 266 74.9 7.3e-13
CCDS3180.1 PTX3 gene_id:5806|Hs108|chr3 ( 381) 250 70.7 1.4e-12
>>CCDS30911.1 CRP gene_id:1401|Hs108|chr1 (224 aa)
initn: 1502 init1: 1502 opt: 1502 Z-score: 2036.9 bits: 384.1 E(32554): 3.9e-107
Smith-Waterman score: 1502; 100.0% identity (100.0% similar) in 224 aa overlap (1-224:1-224)
10 20 30 40 50 60
pF1KE1 MEKLLCFLVLTSLSHAFGQTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLHFYTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 MEKLLCFLVLTSLSHAFGQTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLHFYTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 LSSTRGYSIFSYATKRQDNEILIFWSKDIGYSFTVGGSEILFEVPEVTVAPVHICTSWES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 LSSTRGYSIFSYATKRQDNEILIFWSKDIGYSFTVGGSEILFEVPEVTVAPVHICTSWES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 ASGIVEFWVDGKPRVRKSLKKGYTVGAEASIILGQEQDSFGGNFEGSQSLVGDIGNVNMW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 ASGIVEFWVDGKPRVRKSLKKGYTVGAEASIILGQEQDSFGGNFEGSQSLVGDIGNVNMW
130 140 150 160 170 180
190 200 210 220
pF1KE1 DFVLSPDEINTIYLGGPFSPNVLNWRALKYEVQGEVFTKPQLWP
::::::::::::::::::::::::::::::::::::::::::::
CCDS30 DFVLSPDEINTIYLGGPFSPNVLNWRALKYEVQGEVFTKPQLWP
190 200 210 220
>>CCDS1186.1 APCS gene_id:325|Hs108|chr1 (223 aa)
initn: 769 init1: 582 opt: 777 Z-score: 1056.1 bits: 202.6 E(32554): 1.7e-52
Smith-Waterman score: 777; 51.3% identity (79.5% similar) in 224 aa overlap (1-223:1-222)
10 20 30 40 50
pF1KE1 MEKLLCFL-VLTSLSHAFGQTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLHFYT
:.: : .. ::::: .::..::.: :.::::.:: :..:.: .:: :::. ::.:.. :.
CCDS11 MNKPLLWISVLTSLLEAFAHTDLSGKVFVFPRESVTDHVNLITPLEKPLQNFTLCFRAYS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 ELSSTRGYSIFSYATKRQDNEILIFWSKDIGYSFTVGGSEILFEVPEVTVAPVHICTSWE
.:: :.::.::: :. .:::.:.. . ::. .: .. .: : ::::::.:::
CCDS11 DLS--RAYSLFSYNTQGRDNELLVYKERVGEYSLYIGRHKVTSKVIEKFPAPVHICVSWE
70 80 90 100 110
120 130 140 150 160 170
pF1KE1 SASGIVEFWVDGKPRVRKSLKKGYTVGAEASIILGQEQDSFGGNFEGSQSLVGDIGNVNM
:.:::.:::..: : :.:.:..:: : :. .:.:::::::.::.:. :::.::.::.. :
CCDS11 SSSGIAEFWINGTPLVKKGLRQGYFVEAQPKIVLGQEQDSYGGKFDRSQSFVGEIGDLYM
120 130 140 150 160 170
180 190 200 210 220
pF1KE1 WDFVLSPDEINTIYLGGPFSPNVLNWRALKYEVQGEVFTKPQLWP
:: :: :..: . : : :. :.:.:.::.::..: :. :: .:
CCDS11 WDSVLPPENILSAYQGTPLPANILDWQALNYEIRGYVIIKPLVWV
180 190 200 210 220
>>CCDS32762.1 NPTX1 gene_id:4884|Hs108|chr17 (432 aa)
initn: 223 init1: 138 opt: 304 Z-score: 411.4 bits: 84.3 E(32554): 1.4e-16
Smith-Waterman score: 304; 29.5% identity (61.4% similar) in 207 aa overlap (18-214:218-418)
10 20 30 40
pF1KE1 MEKLLCFLVLTSLSHAFGQTDM---SRKAFVFPKESDTSYVSLKAPL
:: : .. ..:: ... :...: :
CCDS32 KGGPRNDTEERVKIETALTSLHQRISELEKGQKDNRPGDKFQLTFPLRTNYMYAKVKKSL
190 200 210 220 230 240
50 60 70 80 90 100
pF1KE1 TKPLKAFTVCLHFYTELSSTRGYSI-FSYATKRQDNE-ILIFWSKDIGYSFTVGGSEILF
. . :::::. . . :.: : . ::::. : :: .:: :... . . .. .
CCDS32 PE-MYAFTVCM--WLKSSATPGVGTPFSYAVPGQANELVLIEWGNN---PMEILINDKVA
250 260 270 280 290 300
110 120 130 140 150
pF1KE1 EVPEVTVAPV--HICTSWESASGIVEFWVDG-KPRVRKSLKKGYTVGAEASIILGQEQDS
..: : :::..: . .:. : . :: . ..: . . .. ..::::::.
CCDS32 KLPFVINDGKWHHICVTWTTRDGVWEAYQDGTQGGSGENLAPYHPIKPQGVLVLGQEQDT
310 320 330 340 350 360
160 170 180 190 200 210
pF1KE1 FGGNFEGSQSLVGDIGNVNMWDFVLSPDEINTIYLGGP--FSPNVLNWRALKYEVQGEVF
.::.:...:..::.... :.:: :.: :. .. . .: ::. : . :. :
CCDS32 LGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCSTKALSGNVIAWAESHIEIYGGAT
370 380 390 400 410 420
220
pF1KE1 TKPQLWP
CCDS32 KWTFEACRQIN
430
>>CCDS32362.1 PTX4 gene_id:390667|Hs108|chr16 (473 aa)
initn: 247 init1: 177 opt: 289 Z-score: 390.4 bits: 80.5 E(32554): 2e-15
Smith-Waterman score: 289; 30.4% identity (63.0% similar) in 181 aa overlap (27-198:268-443)
10 20 30 40 50
pF1KE1 MEKLLCFLVLTSLSHAFGQTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLH
.:::. : . : :. .. :.:.. :
CCDS32 RVLSGTAPKDPRQQAWSPQVPGEICGVGPTLVFPNASTRNVVFLSPGFVTALRALSFCS-
240 250 260 270 280 290
60 70 80 90 100 110
pF1KE1 FYTELSSTRGYSIFSYATKRQDNEILIFWSKDI---GYSFTVGGSEILFEVPEVTVAPV-
... .: : ...::::. .::. :.. ..: : : :. . :.: .
CCDS32 -WVRTASGRLGTLLSYATEDNDNK-LVLHGRDSLLPGSIHFVIGDPAFRELPLQLLLDGQ
300 310 320 330 340 350
120 130 140 150 160
pF1KE1 --HICTSWESASGIVEFWVDGKPRVRKS---LKKGYTVGAEASIILGQEQDSFGGNFEGS
:::. : :..: ..:. :. . ...:: . .:..::::::: ::.:..:
CCDS32 WHHICVIWTSTQG--RYWLHVDRRLVATGSRFREGYEIPPGGSLVLGQEQDSVGGGFDSS
360 370 380 390 400 410
170 180 190 200 210 220
pF1KE1 QSLVGDIGNVNMWDFVLSPDEINTIYLGGPFSPNVLNWRALKYEVQGEVFTKPQLWP
...::..... .:: .: : :. .. .: :
CCDS32 EAFVGSMSGLAIWDRALVPGEVANLAIGKEFPTGAILTLANAALAGGFVQGANCTCLERC
420 430 440 450 460 470
CCDS32 P
>>CCDS33647.1 NPTXR gene_id:23467|Hs108|chr22 (500 aa)
initn: 255 init1: 165 opt: 281 Z-score: 379.2 bits: 78.5 E(32554): 8.4e-15
Smith-Waterman score: 281; 27.6% identity (59.6% similar) in 203 aa overlap (14-214:285-484)
10 20 30 40
pF1KE1 MEKLLCFLVLTSLSHAFGQTDMSRKAFVFPKESDTSYVSLKAP
: :.. : . . .: ... :. ..
CCDS33 ALSHSSRRQRQEVEKELDVLQGRVAELEHGSSAYSPPDAFKIS--IPIRNNYMYARVRKA
260 270 280 290 300 310
50 60 70 80 90 100
pF1KE1 LTKPLKAFTVCLHFYTELSSTRGYSIFSYATKRQDNEILIFWSKDIGYSFTVGGSEILFE
: . : :::.:. . .. :.: . :::.. : :::... . . . .. . .
CCDS33 LPE-LYAFTACMWLRSRSSGTGQGTPFSYSVPGQANEIVLLEAGHEPMELLINDKVAQLP
320 330 340 350 360 370
110 120 130 140 150 160
pF1KE1 VPEVTVAPVHICTSWESASGIVEFWVDGKPRVR-KSLKKGYTVGAEASIILGQEQDSFGG
. . ::: .: . .:. . ::. . ..: . . .. .:::::::..::
CCDS33 LSLKDNGWHHICIAWTTRDGLWSAYQDGELQGSGENLAAWHPIKPHGILILGQEQDTLGG
380 390 400 410 420 430
170 180 190 200 210 220
pF1KE1 NFEGSQSLVGDIGNVNMWDFVLSPDEINTIY-LGGPFSPNVLNWRALKYEVQGEVFTKPQ
:...:..::::.. :.:: .:.: .. : .:. ::: :. :. :
CCDS33 RFDATQAFVGDIAQFNLWDHALTPAQVLGIANCTAPLLGNVLPWEDKLVEAFGGATKAAF
440 450 460 470 480 490
pF1KE1 LWP
CCDS33 DVCKGRAKA
500
>>CCDS5657.1 NPTX2 gene_id:4885|Hs108|chr7 (431 aa)
initn: 244 init1: 149 opt: 277 Z-score: 374.9 bits: 77.5 E(32554): 1.5e-14
Smith-Waterman score: 277; 30.4% identity (57.9% similar) in 214 aa overlap (16-224:218-420)
10 20 30 40
pF1KE1 MEKLLCFLVLTSLSHAFGQTDMSRKAFVFPKESDTSYVSLKAPLT
:: . : . . .: ... : ..: :
CCDS56 HNETSAHRQKTESTLNALLQRVTELERGNSAFKSPDAFKVS--LPLRTNYLYGKIKKTLP
190 200 210 220 230 240
50 60 70 80 90 100
pF1KE1 KPLKAFTVCLHFYTELSSTRGYSIFSYATKRQDNEI-LIFWSKDIGYSFTVGGSEILFEV
. : :::.:: . . : : . ::::. : ::: :: :... . . .. . ..
CCDS56 E-LYAFTICLWLRSSASPGIG-TPFSYAVPGQANEIVLIEWGNN---PIELLINDKVAQL
250 260 270 280 290 300
110 120 130 140 150 160
pF1KE1 PEVTVAPV--HICTSWESASGIVEFWVDG-KPRVRKSLKKGYTVGAEASIILGQEQDSFG
: . :::..: . .:. : . :: : . ..: . . . .:::::::. :
CCDS56 PLFVSDGKWHHICVTWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQEQDTVG
310 320 330 340 350 360
170 180 190 200 210 220
pF1KE1 GNFEGSQSLVGDIGNVNMWDFVLSPDEINTIYLGGPFSP-NVLNWRALKYEVQGEVFTKP
: :...:..::.... :.:: :: .:: .: . : :.. : . . .::
CCDS56 GRFDATQAFVGELSQFNIWDRVLRAQEIVNIANCSTNMPGNIIPW----VDNNVDVFGGA
370 380 390 400 410
pF1KE1 QLWP
. ::
CCDS56 SKWPVETCEERLLDL
420 430
>>CCDS48004.1 SVEP1 gene_id:79987|Hs108|chr9 (3571 aa)
initn: 211 init1: 147 opt: 266 Z-score: 344.4 bits: 74.9 E(32554): 7.3e-13
Smith-Waterman score: 266; 31.7% identity (64.0% similar) in 186 aa overlap (37-216:1438-1619)
10 20 30 40 50 60
pF1KE1 FLVLTSLSHAFGQTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLHFYTELSSTRG
:: : . : . :.:.: : :. . :. .
CCDS48 KCQPGFSGKRCETEQSTGFNLDFEVSGIYGYVMLDGMLPS-LHALT-CT-FWMKSSDDMN
1410 1420 1430 1440 1450 1460
70 80 90 100 110 120
pF1KE1 YSI-FSYATKRQDNEILIFWSKDIGYSFTVGGSEILFEVPEVTVAPVH-ICTSWESASGI
:. .:::. ... :.. . . :. . :.: : . . : :. . : : .: ::.::
CCDS48 YGTPISYAVDNGSDNTLLLTDYN-GWVLYVNGREKITNCPSVNDGRWHHIAITWTSANGI
1470 1480 1490 1500 1510 1520
130 140 150 160 170 180
pF1KE1 VEFWVDGK-PRVRKSLKKGYTVGAEASIILGQEQDSFGGNFEGSQSLVGDIGNVNMWDFV
. ..::: .:. : . . ....::::::. : .: ..:.::.:...:.::.:
CCDS48 WKVYIDGKLSDGGAGLSVGLPIPGGGALVLGQEQDKKGEGFSPAESFVGSISQLNLWDYV
1530 1540 1550 1560 1570 1580
190 200 210 220
pF1KE1 LSPDEINTIYLGGPF---SPNVLNWRALKYEVQGEVFTKPQLWP
:::...... . : . ::: : . . :.:
CCDS48 LSPQQVKSLATSCPEELSKGNVLAWPDFLSGIVGKVKIDSKSIFCSDCPRLGGSVPHLRT
1590 1600 1610 1620 1630 1640
CCDS48 ASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSA
1650 1660 1670 1680 1690 1700
>>CCDS3180.1 PTX3 gene_id:5806|Hs108|chr3 (381 aa)
initn: 125 init1: 83 opt: 250 Z-score: 339.3 bits: 70.7 E(32554): 1.4e-12
Smith-Waterman score: 250; 28.5% identity (60.0% similar) in 200 aa overlap (26-214:182-375)
10 20 30 40 50
pF1KE1 MEKLLCFLVLTSLSHAFGQTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCL
:..:: .: . :.. :..:..:.
CCDS31 VLEELRQTRADLHAVQGWAARSWLPAGCETAILFPMRSKKIFGSVHPVRPMRLESFSACI
160 170 180 190 200 210
60 70 80 90 100 110
pF1KE1 HFYTELSSTRGYSI-FSYATKRQDNEILIFWSKDIGYSFTVGGSEILFEVPEVTVAP---
... ... . .: :::.:::. :: .. : . . :.::: : . : :. :.
CCDS31 --WVKATDVLNKTILFSYGTKRNPYEIQLYLSYQ-SIVFVVGGEENKL-VAEAMVSLGRW
220 230 240 250 260
120 130 140 150 160
pF1KE1 VHICTSWESASGIVEFWVDGK-PRVRKSLKKGYTVGAEASIILGQEQDS--FGGNFEGSQ
.:.: .:.: :.. .::.:. . . :. : . . .:::... ::.:. .
CCDS31 THLCGTWNSEEGLTSLWVNGELAATTVEMATGHIVPEGGILQIGQEKNGCCVGGGFDETL
270 280 290 300 310 320
170 180 190 200 210 220
pF1KE1 SLVGDIGNVNMWDFVLSPDEINTIYLGGPFS----PNVLNWRALKYEVQGEVFTKPQLWP
.. : . . :.:: ::: .:: :: : :...: . . . .:
CCDS31 AFSGRLTGFNIWDSVLSNEEIRE--TGGAESCHIRGNIVGWGVTEIQPHGGAQYVS
330 340 350 360 370 380
224 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 23:25:22 2016 done: Mon Nov 7 23:25:22 2016
Total Scan time: 2.010 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]