Result of FASTA (omim) for
pFN21AE6195
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6195, 134 aa
1>>>pF1KE6195 134 - 134 aa - 134 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1957+/-0.00032; mu= 11.0439+/- 0.020
mean_var=58.4221+/-11.980, 0's: 0 Z-trim(114.4): 9 B-trim: 0 in 0/57
Lambda= 0.167798
statistics sampled from 24150 (24158) to 24150 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.283), width: 16
Scan time: 3.060
The best scores are: opt bits E(85289)
NP_115497 (OMIM: 300715,300853) magnesium transpor ( 367) 881 221.4 9.4e-58
NP_839952 (OMIM: 601385,611093) tumor suppressor c ( 347) 560 143.7 2.2e-34
NP_006756 (OMIM: 601385,611093) tumor suppressor c ( 348) 560 143.7 2.2e-34
XP_011542956 (OMIM: 601385,611093) PREDICTED: tumo ( 258) 482 124.8 8.2e-29
XP_011542954 (OMIM: 601385,611093) PREDICTED: tumo ( 292) 482 124.8 9.2e-29
XP_016869350 (OMIM: 601385,611093) PREDICTED: tumo ( 292) 482 124.8 9.2e-29
XP_011542953 (OMIM: 601385,611093) PREDICTED: tumo ( 303) 482 124.8 9.5e-29
XP_016869349 (OMIM: 601385,611093) PREDICTED: tumo ( 305) 482 124.8 9.5e-29
>>NP_115497 (OMIM: 300715,300853) magnesium transporter (367 aa)
initn: 881 init1: 881 opt: 881 Z-score: 1157.9 bits: 221.4 E(85289): 9.4e-58
Smith-Waterman score: 881; 97.7% identity (100.0% similar) in 133 aa overlap (1-133:33-165)
10 20 30
pF1KE6 MAARWRFWCVSVTMVVALLIVCDVPSASAQ
::::::::::::::::::::::::::::::
NP_115 KGKGPICLFSRPTLRPSRSKVSLIEGRGANMAARWRFWCVSVTMVVALLIVCDVPSASAQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 RKKEMVLSEKVSQLMEWTNKRPVIRMNGDKFRRLVKAPPRNYSVIVMFTALQLHRQCVVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_115 RKKEMVLSEKVSQLMEWTNKRPVIRMNGDKFRRLVKAPPRNYSVIVMFTALQLHRQCVVC
70 80 90 100 110 120
100 110 120 130
pF1KE6 KQADEEFQILANSWRYSSAFTNRIFFAMVDFDEGSDVFQMFQVF
::::::::::::::::::::::::::::::::::::::::...
NP_115 KQADEEFQILANSWRYSSAFTNRIFFAMVDFDEGSDVFQMLNMNSAPTFINFPAKGKPKR
130 140 150 160 170 180
NP_115 GDTYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAGPLMLGLLLAVIGGLVYLRRSNM
190 200 210 220 230 240
>>NP_839952 (OMIM: 601385,611093) tumor suppressor candi (347 aa)
initn: 550 init1: 550 opt: 560 Z-score: 738.3 bits: 143.7 E(85289): 2.2e-34
Smith-Waterman score: 560; 62.6% identity (90.2% similar) in 123 aa overlap (11-133:24-145)
10 20 30 40
pF1KE6 MAARWRFWCVSVTMVVALLIVCDVPSASAQRKKEMVLSEKVSQLMEW
: ... ::..: . ...:.::: .:.::: :::::
NP_839 MGARGAPSRRRQAGRRLRYLPTGSFPFLLLLLLLC-IQLGGGQKKKENLLAEKVEQLMEW
10 20 30 40 50
50 60 70 80 90 100
pF1KE6 TNKRPVIRMNGDKFRRLVKAPPRNYSVIVMFTALQLHRQCVVCKQADEEFQILANSWRYS
...: ..::::::::...::::::::.:::::::: .::: ::.::.::.::::::::::
NP_839 SSRRSIFRMNGDKFRKFIKAPPRNYSMIVMFTALQPQRQCSVCRQANEEYQILANSWRYS
60 70 80 90 100 110
110 120 130
pF1KE6 SAFTNRIFFAMVDFDEGSDVFQMFQVF
::: :..::.:::.:::.::::....
NP_839 SAFCNKLFFSMVDYDEGTDVFQQLNMNSAPTFMHFPPKGRPKRADTFDLQRIGFAAEQLA
120 130 140 150 160 170
>>NP_006756 (OMIM: 601385,611093) tumor suppressor candi (348 aa)
initn: 550 init1: 550 opt: 560 Z-score: 738.3 bits: 143.7 E(85289): 2.2e-34
Smith-Waterman score: 560; 62.6% identity (90.2% similar) in 123 aa overlap (11-133:24-145)
10 20 30 40
pF1KE6 MAARWRFWCVSVTMVVALLIVCDVPSASAQRKKEMVLSEKVSQLMEW
: ... ::..: . ...:.::: .:.::: :::::
NP_006 MGARGAPSRRRQAGRRLRYLPTGSFPFLLLLLLLC-IQLGGGQKKKENLLAEKVEQLMEW
10 20 30 40 50
50 60 70 80 90 100
pF1KE6 TNKRPVIRMNGDKFRRLVKAPPRNYSVIVMFTALQLHRQCVVCKQADEEFQILANSWRYS
...: ..::::::::...::::::::.:::::::: .::: ::.::.::.::::::::::
NP_006 SSRRSIFRMNGDKFRKFIKAPPRNYSMIVMFTALQPQRQCSVCRQANEEYQILANSWRYS
60 70 80 90 100 110
110 120 130
pF1KE6 SAFTNRIFFAMVDFDEGSDVFQMFQVF
::: :..::.:::.:::.::::....
NP_006 SAFCNKLFFSMVDYDEGTDVFQQLNMNSAPTFMHFPPKGRPKRADTFDLQRIGFAAEQLA
120 130 140 150 160 170
>>XP_011542956 (OMIM: 601385,611093) PREDICTED: tumor su (258 aa)
initn: 482 init1: 482 opt: 482 Z-score: 638.2 bits: 124.8 E(85289): 8.2e-29
Smith-Waterman score: 482; 70.8% identity (95.5% similar) in 89 aa overlap (45-133:1-89)
20 30 40 50 60 70
pF1KE6 VVALLIVCDVPSASAQRKKEMVLSEKVSQLMEWTNKRPVIRMNGDKFRRLVKAPPRNYSV
:::...: ..::::::::...::::::::.
XP_011 MEWSSRRSIFRMNGDKFRKFIKAPPRNYSM
10 20 30
80 90 100 110 120 130
pF1KE6 IVMFTALQLHRQCVVCKQADEEFQILANSWRYSSAFTNRIFFAMVDFDEGSDVFQMFQVF
:::::::: .::: ::.::.::.::::::::::::: :..::.:::.:::.::::....
XP_011 IVMFTALQPQRQCSVCRQANEEYQILANSWRYSSAFCNKLFFSMVDYDEGTDVFQQLNMN
40 50 60 70 80 90
XP_011 SAPTFMHFPPKGRPKRADTFDLQRIGFAAEQLAKWIADRTDVHIRVFRPPNYSGTIALAL
100 110 120 130 140 150
>>XP_011542954 (OMIM: 601385,611093) PREDICTED: tumor su (292 aa)
initn: 482 init1: 482 opt: 482 Z-score: 637.4 bits: 124.8 E(85289): 9.2e-29
Smith-Waterman score: 482; 70.8% identity (95.5% similar) in 89 aa overlap (45-133:1-89)
20 30 40 50 60 70
pF1KE6 VVALLIVCDVPSASAQRKKEMVLSEKVSQLMEWTNKRPVIRMNGDKFRRLVKAPPRNYSV
:::...: ..::::::::...::::::::.
XP_011 MEWSSRRSIFRMNGDKFRKFIKAPPRNYSM
10 20 30
80 90 100 110 120 130
pF1KE6 IVMFTALQLHRQCVVCKQADEEFQILANSWRYSSAFTNRIFFAMVDFDEGSDVFQMFQVF
:::::::: .::: ::.::.::.::::::::::::: :..::.:::.:::.::::....
XP_011 IVMFTALQPQRQCSVCRQANEEYQILANSWRYSSAFCNKLFFSMVDYDEGTDVFQQLNMN
40 50 60 70 80 90
XP_011 SAPTFMHFPPKGRPKRADTFDLQRIGFAAEQLAKWIADRTDVHIRVFRPPNYSGTIALAL
100 110 120 130 140 150
>>XP_016869350 (OMIM: 601385,611093) PREDICTED: tumor su (292 aa)
initn: 482 init1: 482 opt: 482 Z-score: 637.4 bits: 124.8 E(85289): 9.2e-29
Smith-Waterman score: 482; 70.8% identity (95.5% similar) in 89 aa overlap (45-133:1-89)
20 30 40 50 60 70
pF1KE6 VVALLIVCDVPSASAQRKKEMVLSEKVSQLMEWTNKRPVIRMNGDKFRRLVKAPPRNYSV
:::...: ..::::::::...::::::::.
XP_016 MEWSSRRSIFRMNGDKFRKFIKAPPRNYSM
10 20 30
80 90 100 110 120 130
pF1KE6 IVMFTALQLHRQCVVCKQADEEFQILANSWRYSSAFTNRIFFAMVDFDEGSDVFQMFQVF
:::::::: .::: ::.::.::.::::::::::::: :..::.:::.:::.::::....
XP_016 IVMFTALQPQRQCSVCRQANEEYQILANSWRYSSAFCNKLFFSMVDYDEGTDVFQQLNMN
40 50 60 70 80 90
XP_016 SAPTFMHFPPKGRPKRADTFDLQRIGFAAEQLAKWIADRTDVHIRVFRPPNYSGTIALAL
100 110 120 130 140 150
>>XP_011542953 (OMIM: 601385,611093) PREDICTED: tumor su (303 aa)
initn: 482 init1: 482 opt: 482 Z-score: 637.2 bits: 124.8 E(85289): 9.5e-29
Smith-Waterman score: 482; 70.8% identity (95.5% similar) in 89 aa overlap (45-133:1-89)
20 30 40 50 60 70
pF1KE6 VVALLIVCDVPSASAQRKKEMVLSEKVSQLMEWTNKRPVIRMNGDKFRRLVKAPPRNYSV
:::...: ..::::::::...::::::::.
XP_011 MEWSSRRSIFRMNGDKFRKFIKAPPRNYSM
10 20 30
80 90 100 110 120 130
pF1KE6 IVMFTALQLHRQCVVCKQADEEFQILANSWRYSSAFTNRIFFAMVDFDEGSDVFQMFQVF
:::::::: .::: ::.::.::.::::::::::::: :..::.:::.:::.::::....
XP_011 IVMFTALQPQRQCSVCRQANEEYQILANSWRYSSAFCNKLFFSMVDYDEGTDVFQQLNMN
40 50 60 70 80 90
XP_011 SAPTFMHFPPKGRPKRADTFDLQRIGFAAEQLAKWIADRTDVHIRVFRPPNYSGTIALAL
100 110 120 130 140 150
>>XP_016869349 (OMIM: 601385,611093) PREDICTED: tumor su (305 aa)
initn: 482 init1: 482 opt: 482 Z-score: 637.1 bits: 124.8 E(85289): 9.5e-29
Smith-Waterman score: 482; 70.8% identity (95.5% similar) in 89 aa overlap (45-133:1-89)
20 30 40 50 60 70
pF1KE6 VVALLIVCDVPSASAQRKKEMVLSEKVSQLMEWTNKRPVIRMNGDKFRRLVKAPPRNYSV
:::...: ..::::::::...::::::::.
XP_016 MEWSSRRSIFRMNGDKFRKFIKAPPRNYSM
10 20 30
80 90 100 110 120 130
pF1KE6 IVMFTALQLHRQCVVCKQADEEFQILANSWRYSSAFTNRIFFAMVDFDEGSDVFQMFQVF
:::::::: .::: ::.::.::.::::::::::::: :..::.:::.:::.::::....
XP_016 IVMFTALQPQRQCSVCRQANEEYQILANSWRYSSAFCNKLFFSMVDYDEGTDVFQQLNMN
40 50 60 70 80 90
XP_016 SAPTFMHFPPKGRPKRADTFDLQRIGFAAEQLAKWIADRTDVHIRVFRPPNYSGTIALAL
100 110 120 130 140 150
134 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 10:15:05 2016 done: Tue Nov 8 10:15:06 2016
Total Scan time: 3.060 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]