Result of FASTA (omim) for
pFN21AE3772
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3772, 1606 aa
1>>>pF1KE3772 1606 - 1606 aa - 1606 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8924+/-0.000605; mu= 15.7522+/- 0.037
mean_var=163.4272+/-34.830, 0's: 0 Z-trim(110.3): 454 B-trim: 591 in 1/49
Lambda= 0.100326
statistics sampled from 18110 (18668) to 18110 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.553), E-opt: 0.2 (0.219), width: 16
Scan time: 17.570
The best scores are: opt bits E(85289)
NP_079146 (OMIM: 612139) phosphatidylinositol 3,4, (1606) 10699 1563.2 0
XP_011515914 (OMIM: 612139) PREDICTED: phosphatidy (1157) 7629 1118.7 0
NP_079446 (OMIM: 612139) phosphatidylinositol 3,4, ( 979) 6060 891.6 0
NP_065871 (OMIM: 606905) phosphatidylinositol 3,4, (1659) 4126 611.9 1.4e-173
XP_011527236 (OMIM: 606905) PREDICTED: phosphatidy (1259) 2368 357.3 4.7e-97
XP_005263745 (OMIM: 605216) PREDICTED: rho guanine ( 483) 675 111.8 1.4e-23
XP_005263746 (OMIM: 605216) PREDICTED: rho guanine ( 483) 675 111.8 1.4e-23
XP_011509579 (OMIM: 605216) PREDICTED: rho guanine ( 483) 675 111.8 1.4e-23
XP_011509578 (OMIM: 605216) PREDICTED: rho guanine ( 483) 675 111.8 1.4e-23
XP_005263744 (OMIM: 605216) PREDICTED: rho guanine ( 567) 675 111.9 1.6e-23
NP_127462 (OMIM: 605216) rho guanine nucleotide ex ( 670) 675 112.0 1.8e-23
NP_056135 (OMIM: 605216) rho guanine nucleotide ex ( 690) 675 112.0 1.8e-23
XP_011509576 (OMIM: 605216) PREDICTED: rho guanine (1870) 675 112.4 3.6e-23
XP_005263738 (OMIM: 605216) PREDICTED: rho guanine (1876) 675 112.4 3.6e-23
NP_001273724 (OMIM: 613324) spermatogenesis-associ ( 574) 651 108.4 1.8e-22
NP_001273723 (OMIM: 613324) spermatogenesis-associ ( 596) 651 108.5 1.8e-22
NP_694568 (OMIM: 613324) spermatogenesis-associate ( 652) 651 108.5 1.9e-22
XP_011529194 (OMIM: 300429,300607) PREDICTED: rho ( 456) 644 107.3 3.1e-22
NP_001159743 (OMIM: 613324) spermatogenesis-associ (1277) 651 108.8 3.1e-22
NP_001166950 (OMIM: 300429,300607) rho guanine nuc ( 463) 644 107.3 3.1e-22
NP_001273721 (OMIM: 613324) spermatogenesis-associ (1339) 651 108.8 3.2e-22
XP_005262308 (OMIM: 300429,300607) PREDICTED: rho ( 495) 644 107.4 3.2e-22
NP_001317424 (OMIM: 300429,300607) rho guanine nuc ( 495) 644 107.4 3.2e-22
XP_016884857 (OMIM: 300429,300607) PREDICTED: rho ( 495) 644 107.4 3.2e-22
XP_016884856 (OMIM: 300429,300607) PREDICTED: rho ( 495) 644 107.4 3.2e-22
XP_005262307 (OMIM: 300429,300607) PREDICTED: rho ( 495) 644 107.4 3.2e-22
XP_011529192 (OMIM: 300429,300607) PREDICTED: rho ( 516) 644 107.4 3.3e-22
XP_016884855 (OMIM: 300429,300607) PREDICTED: rho ( 516) 644 107.4 3.3e-22
XP_016884854 (OMIM: 300429,300607) PREDICTED: rho ( 516) 644 107.4 3.3e-22
NP_056000 (OMIM: 300429,300607) rho guanine nucleo ( 516) 644 107.4 3.3e-22
XP_016884853 (OMIM: 300429,300607) PREDICTED: rho ( 521) 644 107.4 3.4e-22
XP_016884852 (OMIM: 300429,300607) PREDICTED: rho ( 521) 644 107.4 3.4e-22
XP_005262306 (OMIM: 300429,300607) PREDICTED: rho ( 523) 644 107.4 3.4e-22
XP_016884862 (OMIM: 300429,300607) PREDICTED: rho ( 414) 637 106.3 5.8e-22
NP_001166951 (OMIM: 300429,300607) rho guanine nuc ( 414) 637 106.3 5.8e-22
XP_016884869 (OMIM: 300429,300607) PREDICTED: rho ( 305) 625 104.4 1.6e-21
XP_016884868 (OMIM: 300429,300607) PREDICTED: rho ( 344) 625 104.5 1.7e-21
XP_016884866 (OMIM: 300429,300607) PREDICTED: rho ( 365) 625 104.5 1.8e-21
XP_016884864 (OMIM: 300429,300607) PREDICTED: rho ( 385) 625 104.5 1.8e-21
XP_016884867 (OMIM: 300429,300607) PREDICTED: rho ( 362) 618 103.5 3.5e-21
XP_016884865 (OMIM: 300429,300607) PREDICTED: rho ( 375) 618 103.5 3.6e-21
NP_001273722 (OMIM: 613324) spermatogenesis-associ ( 512) 607 102.0 1.4e-20
NP_073620 (OMIM: 612974) DEP domain-containing mTO ( 409) 523 89.8 5.3e-17
XP_016884863 (OMIM: 300429,300607) PREDICTED: rho ( 412) 503 86.9 4e-16
XP_016884861 (OMIM: 300429,300607) PREDICTED: rho ( 451) 503 86.9 4.2e-16
XP_016884860 (OMIM: 300429,300607) PREDICTED: rho ( 451) 503 86.9 4.2e-16
XP_016884859 (OMIM: 300429,300607) PREDICTED: rho ( 472) 503 86.9 4.4e-16
XP_016884858 (OMIM: 300429,300607) PREDICTED: rho ( 479) 503 86.9 4.4e-16
NP_775829 (OMIM: 605091) FYVE, RhoGEF and PH domai ( 655) 365 67.1 5.6e-10
XP_016865918 (OMIM: 605091) PREDICTED: FYVE, RhoGE ( 662) 365 67.1 5.7e-10
>>NP_079146 (OMIM: 612139) phosphatidylinositol 3,4,5-tr (1606 aa)
initn: 10699 init1: 10699 opt: 10699 Z-score: 8378.9 bits: 1563.2 E(85289): 0
Smith-Waterman score: 10699; 100.0% identity (100.0% similar) in 1606 aa overlap (1-1606:1-1606)
10 20 30 40 50 60
pF1KE3 MSEDSRGDSRAESAKDLEKQLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MSEDSRGDSRAESAKDLEKQLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAASK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VDKNVTEETVKMLFSNIEDILAVHKEFLKVVEECLHPEPNAQQEVGTCFLHFKDKFRIYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VDKNVTEETVKMLFSNIEDILAVHKEFLKVVEECLHPEPNAQQEVGTCFLHFKDKFRIYD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EYCSNHEKAQKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EYCSNHEKAQKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KELLKRTPRKHSDYAAVMEALQAMKAVCSNINEAKRQMEKLEVLEEWQSHIEGWEGSNIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KELLKRTPRKHSDYAAVMEALQAMKAVCSNINEAKRQMEKLEVLEEWQSHIEGWEGSNIT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DTCTEMLMCGVLLKISSGNIQERVFFLFDNLLVYCKRKHRRLKNSKASTDGHRYLFRGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DTCTEMLMCGVLLKISSGNIQERVFFLFDNLLVYCKRKHRRLKNSKASTDGHRYLFRGRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 NTEVMEVENVDDGTADFHSSGHIVVNGWKIHNTAKNKWFVCMAKTPEEKHEWFEAILKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 NTEVMEVENVDDGTADFHSSGHIVVNGWKIHNTAKNKWFVCMAKTPEEKHEWFEAILKER
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 ERRKGLKLGMEQDTWVMISEQGEKLYKMMCRQGNLIKDRKRKLTTFPKCFLGSEFVSWLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 ERRKGLKLGMEQDTWVMISEQGEKLYKMMCRQGNLIKDRKRKLTTFPKCFLGSEFVSWLL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 EIGEIHRPEEGVHLGQALLENGIIHHVTDKHQFKPEQMLYRFRYDDGTFYPRNEMQDVIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EIGEIHRPEEGVHLGQALLENGIIHHVTDKHQFKPEQMLYRFRYDDGTFYPRNEMQDVIS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KGVRLYCRLHSLFTPVIRDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFGVGLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KGVRLYCRLHSLFTPVIRDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFGVGLC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DNGFMHHVLEKSEFKDEPLLFRFFSDEEMEGSNMKHRLMKHDLKVVENVIAKSLLIKSNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DNGFMHHVLEKSEFKDEPLLFRFFSDEEMEGSNMKHRLMKHDLKVVENVIAKSLLIKSNE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 GSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEVGKKIFAINGDLVFMRPFNEVDCFLKSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 GSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEVGKKIFAINGDLVFMRPFNEVDCFLKSCL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 NSRKPLRVLVSTKPRETVKIPDSADGLGFQIRGFGPSVVHAVGRGTVAAAAGLHPGQCII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 NSRKPLRVLVSTKPRETVKIPDSADGLGFQIRGFGPSVVHAVGRGTVAAAAGLHPGQCII
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 KVNGINVSKETHASVIAHVTACRKYRRPTKQDSIQWVYNSIESAQEDLQKSHSKPPGDEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KVNGINVSKETHASVIAHVTACRKYRRPTKQDSIQWVYNSIESAQEDLQKSHSKPPGDEA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 GDAFDCKVEEVIDKFNTMAIIDGKKEHVSLTVDNVHLEYGVVYEYDSTAGIKCNVVEKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 GDAFDCKVEEVIDKFNTMAIIDGKKEHVSLTVDNVHLEYGVVYEYDSTAGIKCNVVEKMI
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 EPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIPTDLQSKFSALCSERIEHLCQRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIPTDLQSKFSALCSERIEHLCQRI
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 SSYKKFSRVLKNRAWPTFKQAKSKISPLHSSDFCPTNCHVNVMEVSYPKTSTSLGSAFGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SSYKKFSRVLKNRAWPTFKQAKSKISPLHSSDFCPTNCHVNVMEVSYPKTSTSLGSAFGV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 QLDSRKHNSHDKENKSSEQGKLSPMVYIQHTITTMAAPSGLSLGQQDGHGLRYLLKEEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QLDSRKHNSHDKENKSSEQGKLSPMVYIQHTITTMAAPSGLSLGQQDGHGLRYLLKEEDL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ETQDIYQKLLGKLQTALKEVEMCVCQIDDLLSSITYSPKLERKTSEGIIPTDSDNEKGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 ETQDIYQKLLGKLQTALKEVEMCVCQIDDLLSSITYSPKLERKTSEGIIPTDSDNEKGER
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 NSKRVCFNVAGDEQEDSGHDTISNRDSYSDCNSNRNSIASFTSICSSQCSSYFHSDEMDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 NSKRVCFNVAGDEQEDSGHDTISNRDSYSDCNSNRNSIASFTSICSSQCSSYFHSDEMDS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 GDELPLSVRISHDKQDKIHSCLEHLFSQVDSITNLLKGQAVVRAFDQTKYLTPGRGLQEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 GDELPLSVRISHDKQDKIHSCLEHLFSQVDSITNLLKGQAVVRAFDQTKYLTPGRGLQEF
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 QQEMEPKLSCPKRLRLHIKQDPWNLPSSVRTLAQNIRKFVEEVKCRLLLALLEYSDSETQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QQEMEPKLSCPKRLRLHIKQDPWNLPSSVRTLAQNIRKFVEEVKCRLLLALLEYSDSETQ
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 LRRDMVFCQTLVATVCAFSEQLMAALNQMFDNSKENEMETWEASRRWLDQIANAGVLFHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 LRRDMVFCQTLVATVCAFSEQLMAALNQMFDNSKENEMETWEASRRWLDQIANAGVLFHF
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 QSLLSPNLTDEQAMLEDTLVALFDLEKVSFYFKPSEEEPLVANVPLTYQAEGSRQALKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QSLLSPNLTDEQAMLEDTLVALFDLEKVSFYFKPSEEEPLVANVPLTYQAEGSRQALKVY
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 FYIDSYHFEQLPQRLKNGGGFKIHPVLFAQALESMEGYYYRDNVSVEEFQAQINAASLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 FYIDSYHFEQLPQRLKNGGGFKIHPVLFAQALESMEGYYYRDNVSVEEFQAQINAASLEK
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 VKQYNQKLRAFYLDKSNSPPNSTSKAAYVDKLMRPLNALDELYRLVASFIRSKRTAACAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VKQYNQKLRAFYLDKSNSPPNSTSKAAYVDKLMRPLNALDELYRLVASFIRSKRTAACAN
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 TACSASGVGLLSVSSELCNRLGACHIIMCSSGVHRCTLSVTLEQAIILARSHGLPPRYIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 TACSASGVGLLSVSSELCNRLGACHIIMCSSGVHRCTLSVTLEQAIILARSHGLPPRYIM
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600
pF1KE3 QATDVMRKQGARVQNTAKNLGVRDRTPQSAPRLYKLCEPPPPAGEE
::::::::::::::::::::::::::::::::::::::::::::::
NP_079 QATDVMRKQGARVQNTAKNLGVRDRTPQSAPRLYKLCEPPPPAGEE
1570 1580 1590 1600
>>XP_011515914 (OMIM: 612139) PREDICTED: phosphatidylino (1157 aa)
initn: 7629 init1: 7629 opt: 7629 Z-score: 5979.2 bits: 1118.7 E(85289): 0
Smith-Waterman score: 7629; 100.0% identity (100.0% similar) in 1141 aa overlap (1-1141:1-1141)
10 20 30 40 50 60
pF1KE3 MSEDSRGDSRAESAKDLEKQLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSEDSRGDSRAESAKDLEKQLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAASK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VDKNVTEETVKMLFSNIEDILAVHKEFLKVVEECLHPEPNAQQEVGTCFLHFKDKFRIYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDKNVTEETVKMLFSNIEDILAVHKEFLKVVEECLHPEPNAQQEVGTCFLHFKDKFRIYD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EYCSNHEKAQKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYCSNHEKAQKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KELLKRTPRKHSDYAAVMEALQAMKAVCSNINEAKRQMEKLEVLEEWQSHIEGWEGSNIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KELLKRTPRKHSDYAAVMEALQAMKAVCSNINEAKRQMEKLEVLEEWQSHIEGWEGSNIT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DTCTEMLMCGVLLKISSGNIQERVFFLFDNLLVYCKRKHRRLKNSKASTDGHRYLFRGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTCTEMLMCGVLLKISSGNIQERVFFLFDNLLVYCKRKHRRLKNSKASTDGHRYLFRGRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 NTEVMEVENVDDGTADFHSSGHIVVNGWKIHNTAKNKWFVCMAKTPEEKHEWFEAILKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NTEVMEVENVDDGTADFHSSGHIVVNGWKIHNTAKNKWFVCMAKTPEEKHEWFEAILKER
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 ERRKGLKLGMEQDTWVMISEQGEKLYKMMCRQGNLIKDRKRKLTTFPKCFLGSEFVSWLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERRKGLKLGMEQDTWVMISEQGEKLYKMMCRQGNLIKDRKRKLTTFPKCFLGSEFVSWLL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 EIGEIHRPEEGVHLGQALLENGIIHHVTDKHQFKPEQMLYRFRYDDGTFYPRNEMQDVIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EIGEIHRPEEGVHLGQALLENGIIHHVTDKHQFKPEQMLYRFRYDDGTFYPRNEMQDVIS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KGVRLYCRLHSLFTPVIRDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFGVGLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGVRLYCRLHSLFTPVIRDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFGVGLC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DNGFMHHVLEKSEFKDEPLLFRFFSDEEMEGSNMKHRLMKHDLKVVENVIAKSLLIKSNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNGFMHHVLEKSEFKDEPLLFRFFSDEEMEGSNMKHRLMKHDLKVVENVIAKSLLIKSNE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 GSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEVGKKIFAINGDLVFMRPFNEVDCFLKSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEVGKKIFAINGDLVFMRPFNEVDCFLKSCL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 NSRKPLRVLVSTKPRETVKIPDSADGLGFQIRGFGPSVVHAVGRGTVAAAAGLHPGQCII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSRKPLRVLVSTKPRETVKIPDSADGLGFQIRGFGPSVVHAVGRGTVAAAAGLHPGQCII
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 KVNGINVSKETHASVIAHVTACRKYRRPTKQDSIQWVYNSIESAQEDLQKSHSKPPGDEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVNGINVSKETHASVIAHVTACRKYRRPTKQDSIQWVYNSIESAQEDLQKSHSKPPGDEA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 GDAFDCKVEEVIDKFNTMAIIDGKKEHVSLTVDNVHLEYGVVYEYDSTAGIKCNVVEKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDAFDCKVEEVIDKFNTMAIIDGKKEHVSLTVDNVHLEYGVVYEYDSTAGIKCNVVEKMI
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 EPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIPTDLQSKFSALCSERIEHLCQRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIPTDLQSKFSALCSERIEHLCQRI
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 SSYKKFSRVLKNRAWPTFKQAKSKISPLHSSDFCPTNCHVNVMEVSYPKTSTSLGSAFGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSYKKFSRVLKNRAWPTFKQAKSKISPLHSSDFCPTNCHVNVMEVSYPKTSTSLGSAFGV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 QLDSRKHNSHDKENKSSEQGKLSPMVYIQHTITTMAAPSGLSLGQQDGHGLRYLLKEEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLDSRKHNSHDKENKSSEQGKLSPMVYIQHTITTMAAPSGLSLGQQDGHGLRYLLKEEDL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 ETQDIYQKLLGKLQTALKEVEMCVCQIDDLLSSITYSPKLERKTSEGIIPTDSDNEKGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETQDIYQKLLGKLQTALKEVEMCVCQIDDLLSSITYSPKLERKTSEGIIPTDSDNEKGER
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 NSKRVCFNVAGDEQEDSGHDTISNRDSYSDCNSNRNSIASFTSICSSQCSSYFHSDEMDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSKRVCFNVAGDEQEDSGHDTISNRDSYSDCNSNRNSIASFTSICSSQCSSYFHSDEMDS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 GDELPLSVRISHDKQDKIHSCLEHLFSQVDSITNLLKGQAVVRAFDQTKYLTPGRGLQEF
:
XP_011 GGFNYQSPKRAGCCEGL
1150
>>NP_079446 (OMIM: 612139) phosphatidylinositol 3,4,5-tr (979 aa)
initn: 6055 init1: 6055 opt: 6060 Z-score: 4752.7 bits: 891.6 E(85289): 0
Smith-Waterman score: 6060; 94.5% identity (96.4% similar) in 968 aa overlap (1-967:1-960)
10 20 30 40 50 60
pF1KE3 MSEDSRGDSRAESAKDLEKQLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAASK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MSEDSRGDSRAESAKDLEKQLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAASK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VDKNVTEETVKMLFSNIEDILAVHKEFLKVVEECLHPEPNAQQEVGTCFLHFKDKFRIYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VDKNVTEETVKMLFSNIEDILAVHKEFLKVVEECLHPEPNAQQEVGTCFLHFKDKFRIYD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EYCSNHEKAQKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EYCSNHEKAQKLLLELNKIRTIRTFLLNCMLLGGRKNTDVPLEGYLVTPIQRICKYPLIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KELLKRTPRKHSDYAAVMEALQAMKAVCSNINEAKRQMEKLEVLEEWQSHIEGWEGSNIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KELLKRTPRKHSDYAAVMEALQAMKAVCSNINEAKRQMEKLEVLEEWQSHIEGWEGSNIT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DTCTEMLMCGVLLKISSGNIQERVFFLFDNLLVYCKRKHRRLKNSKASTDGHRYLFRGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DTCTEMLMCGVLLKISSGNIQERVFFLFDNLLVYCKRKHRRLKNSKASTDGHRYLFRGRI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 NTEVMEVENVDDGTADFHSSGHIVVNGWKIHNTAKNKWFVCMAKTPEEKHEWFEAILKER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 NTEVMEVENVDDGTADFHSSGHIVVNGWKIHNTAKNKWFVCMAKTPEEKHEWFEAILKER
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 ERRKGLKLGMEQDTWVMISEQGEKLYKMMCRQGNLIKDRKRKLTTFPKCFLGSEFVSWLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 ERRKGLKLGMEQDTWVMISEQGEKLYKMMCRQGNLIKDRKRKLTTFPKCFLGSEFVSWLL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 EIGEIHRPEEGVHLGQALLENGIIHHVTDKHQFKPEQMLYRFRYDDGTFYPRNEMQDVIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EIGEIHRPEEGVHLGQALLENGIIHHVTDKHQFKPEQMLYRFRYDDGTFYPRNEMQDVIS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KGVRLYCRLHSLFTPVIRDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFGVGLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KGVRLYCRLHSLFTPVIRDKDYHLRTYKSVVMANKLIDWLIAQGDCRTREEAMIFGVGLC
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DNGFMHHVLEKSEFKDEPLLFRFFSDEEMEGSNMKHRLMKHDLKVVENVIAKSLLIKSNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DNGFMHHVLEKSEFKDEPLLFRFFSDEEMEGSNMKHRLMKHDLKVVENVIAKSLLIKSNE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 GSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEVGKKIFAINGDLVFMRPFNEVDCFLKSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 GSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEVGKKIFAINGDLVFMRPFNEVDCFLKSCL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 NSRKPLRVLVSTKPRETVKIPDSADGLGFQIRGFGPSVVHAVGRGTVAAAAGLHPGQCII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 NSRKPLRVLVSTKPRETVKIPDSADGLGFQIRGFGPSVVHAVGRGTVAAAAGLHPGQCII
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 KVNGINVSKETHASVIAHVTACRKYRRPTKQDSIQWVYNSIESAQEDLQKSHSKPPGDEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KVNGINVSKETHASVIAHVTACRKYRRPTKQDSIQWVYNSIESAQEDLQKSHSKPPGDEA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 GDAFDCKVEEVIDKFNTMAIIDGKKEHVSLTVDNVHLEYGVVYEYDSTAGIKCNVVEKMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 GDAFDCKVEEVIDKFNTMAIIDGKKEHVSLTVDNVHLEYGVVYEYDSTAGIKCNVVEKMI
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 EPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIPTDLQSKFSALCSERIEHLCQRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNEVIPTDLQSKFSALCSERIEHLCQRI
850 860 870 880 890 900
910 920 930 940 950
pF1KE3 SSYKKFSRVLKNRAWPTFKQAKSKISPLHS-SDFCPTNCHVNVMEVSYPKTSTSLGSAFG
::::: . . . . . . . ::: :. :. .. . . : .:
NP_079 SSYKKVQASERFYNFTARHAVWEHSFDLHSVSSTFPVPVTMEFLLLPPP--------LLG
910 920 930 940 950
960 970 980 990 1000 1010
pF1KE3 VQLDSRKHNSHDKENKSSEQGKLSPMVYIQHTITTMAAPSGLSLGQQDGHGLRYLLKEED
.. :.:.:
NP_079 ISQDGRQHCIPEDLPSQEMLLAERAPV
960 970
>>NP_065871 (OMIM: 606905) phosphatidylinositol 3,4,5-tr (1659 aa)
initn: 5033 init1: 1608 opt: 4126 Z-score: 3237.1 bits: 611.9 E(85289): 1.4e-173
Smith-Waterman score: 6136; 57.4% identity (80.8% similar) in 1640 aa overlap (5-1600:31-1654)
10 20 30
pF1KE3 MSEDSRGDSRAESAKDLEKQLRLRVCVLSELQKT
: : . .:.. :.:::::.:::.:. :
NP_065 MEAPSGSEPGGDGAGDCAHPDPRAPGAAAPSSGPGPCAAARESERQLRLRLCVLNEILGT
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 ERDYVGTLEFLVSAFLHRMNQCAASKVDKNVTEETVKMLFSNIEDILAVHKEFLKVVEEC
::::::::.:: ::::::. : .:..:.:..:::.::.::::::::: :::.:: ..: :
NP_065 ERDYVGTLRFLQSAFLHRIRQNVADSVEKGLTEENVKVLFSNIEDILEVHKDFLAALEYC
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 LHPEPNAQQEVGTCFLHFKDKFRIYDEYCSNHEKAQKLLLELNKIRTIRTFLLNCMLLGG
:::::..:.:.:. ::.::::: .:.::::::::: .::.::::: :.:.:::.::::::
NP_065 LHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLVELNKIPTVRAFLLSCMLLGG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 RKNTDVPLEGYLVTPIQRICKYPLILKELLKRTPRKHSDYAAVMEALQAMKAVCSNINEA
::.::.::::::..::::::::::.:::: :::: :: :. ::. ::::::.:::::::.
NP_065 RKTTDIPLEGYLLSPIQRICKYPLLLKELAKRTPGKHPDHPAVQSALQAMKTVCSNINET
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE3 KRQMEKLEVLEEWQSHIEGWEGSNITDTCTEMLMCGVLLKISSGNIQERVFFLFDNLLVY
::::::::.::. :::::::::::.:: ::..:. :.:::::.::::::.::::::::::
NP_065 KRQMEKLEALEQLQSHIEGWEGSNLTDICTQLLLQGTLLKISAGNIQERAFFLFDNLLVY
250 260 270 280 290 300
280 290 300 310 320
pF1KE3 CKRKHRRLKNSKAST------DGHRYLFRGRINTEVMEVENVDDGTADFHSSGHIVVNGW
:::: : . .:: :: .: :.:::::::::::::::.:::::.::.:. :.:::
NP_065 CKRKSR-VTGSKKSTKRTKSINGSLYIFRGRINTEVMEVENVEDGTADYHSNGYTVTNGW
310 320 330 340 350
330 340 350 360 370 380
pF1KE3 KIHNTAKNKWFVCMAKTPEEKHEWFEAILKERERRKGLKLGMEQDTWVMISEQGEKLYKM
::::::::::::::::: :::..:..::..:::.:..::::::.:..:::.:.:::::.:
NP_065 KIHNTAKNKWFVCMAKTAEEKQKWLDAIIREREQRESLKLGMERDAYVMIAEKGEKLYHM
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE3 MC-RQGNLIKDRKRKLTTFPKCFLGSEFVSWLLEIGEIHRPEEGVHLGQALLENGIIHHV
: .. ::::::.:::.: ::::::.:::.:::::::: . ::::.::::::::::::::
NP_065 MMNKKVNLIKDRRRKLSTVPKCFLGNEFVAWLLEIGEISKTEEGVNLGQALLENGIIHHV
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE3 TDKHQFKPEQMLYRFRYDDGTFYPRNEMQDVISKGVRLYCRLHSLFTPVIRDKDYHLRTY
.:::::: ::..:::::::::. :.:..:..:::::::::::::.::::.:.::::.::
NP_065 SDKHQFKNEQVMYRFRYDDGTYKARSELEDIMSKGVRLYCRLHSLYTPVIKDRDYHLKTY
480 490 500 510 520 530
510 520 530 540 550 560
pF1KE3 KSVVMANKLIDWLIAQGDCRTREEAMIFGVGLCDNGFMHHVLEKSEFKDEPLLFRFFSDE
:::. ..::.:::.:::::.:::::. .:::::.:::::::::::::.:: ::: .::
NP_065 KSVLPGSKLVDWLLAQGDCQTREEAVALGVGLCNNGFMHHVLEKSEFRDESQYFRFHADE
540 550 560 570 580 590
570 580 590 600 610 620
pF1KE3 EMEGSNMKHRLMKHDLKVVENVIAKSLLIKSNEGSYGFGLEDKNKVPIIKLVEKGSNAEM
::::.. :.. ...:.:.:::..:: ::: .: .::: .:.:::. ..: :..:: ::.
NP_065 EMEGTSSKNKQLRNDFKLVENILAKRLLILPQEEDYGFDIEEKNKAVVVKSVQRGSLAEV
600 610 620 630 640 650
630 640 650 660 670 680
pF1KE3 AGMEVGKKIFAINGDLVFMRPFNEVDCFLKSCLNSRKPLRVLVSTKPRETVKIPDSADGL
::..::.::..:: ::::.:::.::. .:.. . ::.:::.::.:: .: .::::. : :
NP_065 AGLQVGRKIYSINEDLVFLRPFSEVESILNQSFCSRRPLRLLVATKAKEIIKIPDQPDTL
660 670 680 690 700 710
690 700 710 720 730 740
pF1KE3 GFQIRGFGPSVVHAVGRGTVAAAAGLHPGQCIIKVNGINVSKETHASVIAHVTACRKYRR
::::: .: :.:::::. : :::: ::::.:::: :: .. :. : : :. ::
NP_065 CFQIRGAAPPYVYAVGRGSEAMAAGLCAGQCILKVNGSNVMNDGAPEVLEHFQAFRS-RR
720 730 740 750 760 770
750 760 770 780 790 800
pF1KE3 PTKQDSIQWVYNSIESAQE---DLQKSHSKPPGDEAGDAFDCKVEEVIDKFNTMAIIDGK
::.:.. :.::: . . : : :..: . . . ... .
NP_065 EEALGLYQWIYHTHEDAQEARASQEASTEDPSGEQAQEEDQADSAFPLLSLGPRLSLCED
780 790 800 810 820 830
810 820 830 840 850 860
pF1KE3 KEHVSLTVDNVHLEYGVVYEYDSTAGIKCNVVEKMIEPKGFFSLTAKILEALAKSDEHFV
. :.:::::::::.:::::: ::::..:.:.::..::.: :.::::::::.: .: ::
NP_065 SPMVTLTVDNVHLEHGVVYEYVSTAGVRCHVLEKIVEPRGCFGLTAKILEAFAANDSVFV
840 850 860 870 880 890
870 880 890 900 910 920
pF1KE3 QNCTSLNSLNEVIPTDLQSKFSALCSERIEHLCQRISSYKKFSRVLKNRAWPTFKQAKSK
.:: : .:. .: : . .: .:. ..: . :::. :..:. ::.:. : :::: .
NP_065 ENCRRLMALSSAIVTMPHFEFRNICDTKLESIGQRIACYQEFAAQLKSRVSPPFKQAPLE
900 910 920 930 940 950
930 940 950 960 970 980
pF1KE3 ISPLHSSDFCPTNCHVNVMEVSYPKTSTSLGSAFGVQLDSRKHNSHDKENKSSEQGKLSP
:: . ::::::::.:.::::::::. :.: .:.... .:: . . :::.:.:
NP_065 PHPLCGLDFCPTNCHINLMEVSYPKTTPSVGRSFSIRF-GRKPSLIGLD---PEQGHLNP
960 970 980 990 1000 1010
990 1000 1010 1020
pF1KE3 MVYIQHTITTMAAPS--------------GL----------SLGQQDGHGLRYLLKEEDL
: : :: :::::::: :: .:::.: .:: .:::.::
NP_065 MSYTQHCITTMAAPSWKCLPAAEGDPQGQGLHDGSFGPASGTLGQED-RGLSFLLKQEDR
1020 1030 1040 1050 1060 1070
1030 1040 1050 1060 1070
pF1KE3 ETQDIYQKLLGKLQTALKEVEMCVCQIDDLLSSITYSPK--------LERKTSEGIIPTD
: :: : .:. ::..::::... : ::. :::.:: . :. .: .. .
NP_065 EIQDAYLQLFTKLDVALKEMKQYVTQINRLLSTITEPTSGGSCDASLAEEASSLPLVSEE
1080 1090 1100 1110 1120 1130
1080 1090 1100 1110 1120 1130
pF1KE3 SDNEKGERNS-KRVCFNVAGDEQEDSGHDTISNRDSYSDCNSNRNSIASFTSICSSQCSS
:. ....... :.:::.:: ..::::::::.: :::::.:::::.:. :.::. :. ::
NP_065 SEMDRSDHGGIKKVCFKVAEEDQEDSGHDTMSYRDSYSECNSNRDSVLSYTSVRSN--SS
1140 1150 1160 1170 1180 1190
1140 1150 1160 1170 1180 1190
pF1KE3 YFHSDEMDSGDELPLSVRISHDKQDKIHSCLEHLFSQVDSITNLLKGQAVVRAFDQTKYL
:. :::: :::::: ..:: :::::.:.::::::.:::::. :::: .. :::..::..
NP_065 YLGSDEMGSGDELPCDMRIPSDKQDKLHGCLEHLFNQVDSINALLKGPVMSRAFEETKHF
1200 1210 1220 1230 1240 1250
1200 1210 1220 1230 1240 1250
pF1KE3 TPGRGLQEFQQEMEPKLSCPKRLRLHIKQDPWNLPSSVRTLAQNIRKFVEEVKCRLLLAL
...::::.:. : . . ... :..::::::.:..::..::...::. : .:::::
NP_065 PMNHSLQEFKQKEECTIRGRSLIQISIQEDPWNLPNSIKTLVDNIQRYVEDGKNQLLLAL
1260 1270 1280 1290 1300 1310
1260 1270 1280 1290 1300 1310
pF1KE3 LEYSDSETQLRRDMVFCQTLVATVCAFSEQLMAALNQMFDNSKENEMETWEASRRWLDQI
:. .:.: ::::: .:::.:::.::.:::::.:::. ..:. : : . .:::.::.:.
NP_065 LKCTDTELQLRRDAIFCQALVAAVCTFSEQLLAALGYRYNNNGEYEESSRDASRKWLEQV
1320 1330 1340 1350 1360 1370
1320 1330 1340 1350 1360 1370
pF1KE3 ANAGVLFHFQSLLSP-NLTDEQAMLEDTLVALFDLEKVSFYFKPSEEEPLVANVPLTYQA
: .:::.: :::::: .. .:..:::: :.: .:..:.: :: .:. :::. . :.
NP_065 AATGVLLHCQSLLSPATVKEERTMLEDIWVTLSELDNVTFSFKQLDEN-YVANTNVFYHI
1380 1390 1400 1410 1420 1430
1380 1390 1400 1410 1420 1430
pF1KE3 EGSRQALKVYFYIDSYHFEQLPQRLKNGGGFKIHPVLFAQALESMEGYYYRDNVSVEEFQ
::::::::: ::.::::: .::.::..:.....: .::...::..:: . ..:..:
NP_065 EGSRQALKVIFYLDSYHFSKLPSRLEGGASLRLHTALFTKVLENVEGLPSPGSQAAEDLQ
1440 1450 1460 1470 1480 1490
1440 1450 1460 1470 1480 1490
pF1KE3 AQINAASLEKVKQYNQKLRAFYLDKSNSPPNSTSKAAYVDKLMRPLNALDELYRLVASFI
.::: :::::.:: .:::::::..:: : .... :. .:.:.::.:::::: ::. ::.
NP_065 QDINAQSLEKVQQYYRKLRAFYLERSNLPTDASTTAVKIDQLIRPINALDELCRLMKSFV
1500 1510 1520 1530 1540 1550
1500 1510 1520 1530 1540 1550
pF1KE3 RSKRTAACANTACSASGVGLLSVSSELCNRLGACHIIMCSSGVHRCTLSVTLEQAIILAR
. : :: .. :.::. .::::: :::::...::..:..: ::::.:::: ::::
NP_065 HPKPGAA------GSVGAGLIPISSELCYRLGACQMVMCGTGMQRSTLSVSLEQAAILAR
1560 1570 1580 1590 1600
1560 1570 1580 1590 1600
pF1KE3 SHGLPPRYIMQATDVMRKQGARVQNTAKNLGVRDRTPQSAPRLYKLCEPPPPAGEE
:::: :. ::::::.::::: ::. :::: :.:. ::.:::::.::.::
NP_065 SHGLLPKCIMQATDIMRKQGPRVEILAKNLRVKDQMPQGAPRLYRLCQPPVDGDL
1610 1620 1630 1640 1650
>>XP_011527236 (OMIM: 606905) PREDICTED: phosphatidylino (1259 aa)
initn: 3707 init1: 1608 opt: 2368 Z-score: 1863.4 bits: 357.3 E(85289): 4.7e-97
Smith-Waterman score: 4373; 53.6% identity (78.3% similar) in 1269 aa overlap (370-1600:1-1254)
340 350 360 370 380 390
pF1KE3 VCMAKTPEEKHEWFEAILKERERRKGLKLGMEQDTWVMISEQGEKLYKMMC-RQGNLIKD
::.:..:::.:.:::::.:: .. :::::
XP_011 MERDAYVMIAEKGEKLYHMMMNKKVNLIKD
10 20 30
400 410 420 430 440 450
pF1KE3 RKRKLTTFPKCFLGSEFVSWLLEIGEIHRPEEGVHLGQALLENGIIHHVTDKHQFKPEQM
:.:::.: ::::::.:::.:::::::: . ::::.::::::::::::::.:::::: ::.
XP_011 RRRKLSTVPKCFLGNEFVAWLLEIGEISKTEEGVNLGQALLENGIIHHVSDKHQFKNEQV
40 50 60 70 80 90
460 470 480 490 500 510
pF1KE3 LYRFRYDDGTFYPRNEMQDVISKGVRLYCRLHSLFTPVIRDKDYHLRTYKSVVMANKLID
.:::::::::. :.:..:..:::::::::::::.::::.:.::::.:::::. ..::.:
XP_011 MYRFRYDDGTYKARSELEDIMSKGVRLYCRLHSLYTPVIKDRDYHLKTYKSVLPGSKLVD
100 110 120 130 140 150
520 530 540 550 560 570
pF1KE3 WLIAQGDCRTREEAMIFGVGLCDNGFMHHVLEKSEFKDEPLLFRFFSDEEMEGSNMKHRL
::.:::::.:::::. .:::::.:::::::::::::.:: ::: .::::::.. :..
XP_011 WLLAQGDCQTREEAVALGVGLCNNGFMHHVLEKSEFRDESQYFRFHADEEMEGTSSKNKQ
160 170 180 190 200 210
580 590 600 610 620 630
pF1KE3 MKHDLKVVENVIAKSLLIKSNEGSYGFGLEDKNKVPIIKLVEKGSNAEMAGMEVGKKIFA
...:.:.:::..:: ::: .: .::: .:.:::. ..: :..:: ::.::..::.::..
XP_011 LRNDFKLVENILAKRLLILPQEEDYGFDIEEKNKAVVVKSVQRGSLAEVAGLQVGRKIYS
220 230 240 250 260 270
640 650 660 670 680 690
pF1KE3 INGDLVFMRPFNEVDCFLKSCLNSRKPLRVLVSTKPRETVKIPDSADGLGFQIRGFGPSV
:: ::::.:::.::. .:.. . ::.:::.::.:: .: .::::. : : ::::: .:
XP_011 INEDLVFLRPFSEVESILNQSFCSRRPLRLLVATKAKEIIKIPDQPDTLCFQIRGAAPPY
280 290 300 310 320 330
700 710 720 730 740 750
pF1KE3 VHAVGRGTVAAAAGLHPGQCIIKVNGINVSKETHASVIAHVTACRKYRRPTKQDSIQWVY
:.:::::. : :::: ::::.:::: :: .. :. : : :. :: ::.:
XP_011 VYAVGRGSEAMAAGLCAGQCILKVNGSNVMNDGAPEVLEHFQAFRS-RREEALGLYQWIY
340 350 360 370 380
760 770 780 790 800 810
pF1KE3 NSIESAQE---DLQKSHSKPPGDEAGDAFDCKVEEVIDKFNTMAIIDGKKEHVSLTVDNV
.. :.::: . . : : :..: . . . ... . . :.::::::
XP_011 HTHEDAQEARASQEASTEDPSGEQAQEEDQADSAFPLLSLGPRLSLCEDSPMVTLTVDNV
390 400 410 420 430 440
820 830 840 850 860 870
pF1KE3 HLEYGVVYEYDSTAGIKCNVVEKMIEPKGFFSLTAKILEALAKSDEHFVQNCTSLNSLNE
:::.:::::: ::::..:.:.::..::.: :.::::::::.: .: ::.:: : .:.
XP_011 HLEHGVVYEYVSTAGVRCHVLEKIVEPRGCFGLTAKILEAFAANDSVFVENCRRLMALSS
450 460 470 480 490 500
880 890 900 910 920 930
pF1KE3 VIPTDLQSKFSALCSERIEHLCQRISSYKKFSRVLKNRAWPTFKQAKSKISPLHSSDFCP
.: : . .: .:. ..: . :::. :..:. ::.:. : :::: . :: . ::::
XP_011 AIVTMPHFEFRNICDTKLESIGQRIACYQEFAAQLKSRVSPPFKQAPLEPHPLCGLDFCP
510 520 530 540 550 560
940 950 960 970 980 990
pF1KE3 TNCHVNVMEVSYPKTSTSLGSAFGVQLDSRKHNSHDKENKSSEQGKLSPMVYIQHTITTM
::::.:.::::::::. :.: .:.... .:: . . :::.:.:: : :: ::::
XP_011 TNCHINLMEVSYPKTTPSVGRSFSIRF-GRKPSLIGLD---PEQGHLNPMSYTQHCITTM
570 580 590 600 610 620
1000 1010 1020 1030
pF1KE3 AAPS--------------GL----------SLGQQDGHGLRYLLKEEDLETQDIYQKLLG
:::: :: .:::.: .:: .:::.:: : :: : .:.
XP_011 AAPSWKCLPAAEGDPQGQGLHDGSFGPASGTLGQED-RGLSFLLKQEDREIQDAYLQLFT
630 640 650 660 670 680
1040 1050 1060 1070 1080
pF1KE3 KLQTALKEVEMCVCQIDDLLSSITYSPK--------LERKTSEGIIPTDSDNEKGERNS-
::..::::... : ::. :::.:: . :. .: .. .:. .......
XP_011 KLDVALKEMKQYVTQINRLLSTITEPTSGGSCDASLAEEASSLPLVSEESEMDRSDHGGI
690 700 710 720 730 740
1090 1100 1110 1120 1130 1140
pF1KE3 KRVCFNVAGDEQEDSGHDTISNRDSYSDCNSNRNSIASFTSICSSQCSSYFHSDEMDSGD
:.:::.:: ..::::::::.: :::::.:::::.:. :.::. :. :::. :::: :::
XP_011 KKVCFKVAEEDQEDSGHDTMSYRDSYSECNSNRDSVLSYTSVRSN--SSYLGSDEMGSGD
750 760 770 780 790 800
1150 1160 1170 1180 1190 1200
pF1KE3 ELPLSVRISHDKQDKIHSCLEHLFSQVDSITNLLKGQAVVRAFDQTKYLTPGRGLQEFQQ
::: ..:: :::::.:.::::::.:::::. :::: .. :::..::.. ...::::.:
XP_011 ELPCDMRIPSDKQDKLHGCLEHLFNQVDSINALLKGPVMSRAFEETKHFPMNHSLQEFKQ
810 820 830 840 850 860
1210 1220 1230 1240 1250 1260
pF1KE3 EMEPKLSCPKRLRLHIKQDPWNLPSSVRTLAQNIRKFVEEVKCRLLLALLEYSDSETQLR
. : . . ... :..::::::.:..::..::...::. : .::::::. .:.: :::
XP_011 KEECTIRGRSLIQISIQEDPWNLPNSIKTLVDNIQRYVEDGKNQLLLALLKCTDTELQLR
870 880 890 900 910 920
1270 1280 1290 1300 1310 1320
pF1KE3 RDMVFCQTLVATVCAFSEQLMAALNQMFDNSKENEMETWEASRRWLDQIANAGVLFHFQS
:: .:::.:::.::.::.::.:::. ..:. : : . .:::.::.:.: .:::.: ::
XP_011 RDAIFCQALVAAVCTFSKQLLAALGYRYNNNGEYEESSRDASRKWLEQVAATGVLLHCQS
930 940 950 960 970 980
1330 1340 1350 1360 1370 1380
pF1KE3 LLSP-NLTDEQAMLEDTLVALFDLEKVSFYFKPSEEEPLVANVPLTYQAEGSRQALKVYF
:::: .. .:..:::: :.: .:..:.: :: .:. :::. . :. ::::::::: :
XP_011 LLSPATVKEERTMLEDIWVTLSELDNVTFSFKQLDEN-YVANTNVFYHIEGSRQALKVIF
990 1000 1010 1020 1030 1040
1390 1400 1410 1420 1430 1440
pF1KE3 YIDSYHFEQLPQRLKNGGGFKIHPVLFAQALESMEGYYYRDNVSVEEFQAQINAASLEKV
:.::::: .::.::..:.....: .::...::..:: . ..:..: .::: :::::
XP_011 YLDSYHFSKLPSRLEGGASLRLHTALFTKVLENVEGLPSPGSQAAEDLQQDINAQSLEKV
1050 1060 1070 1080 1090 1100
1450 1460 1470 1480 1490 1500
pF1KE3 KQYNQKLRAFYLDKSNSPPNSTSKAAYVDKLMRPLNALDELYRLVASFIRSKRTAACANT
.:: .:::::::..:: : .... :. .:.:.::.:::::: ::. ::.. : ::
XP_011 QQYYRKLRAFYLERSNLPTDASTTAVKIDQLIRPINALDELCRLMKSFVHPKPGAA----
1110 1120 1130 1140 1150
1510 1520 1530 1540 1550 1560
pF1KE3 ACSASGVGLLSVSSELCNRLGACHIIMCSSGVHRCTLSVTLEQAIILARSHGLPPRYIMQ
.. :.::. .::::: :::::...::..:..: ::::.:::: :::::::: :. :::
XP_011 --GSVGAGLIPISSELCYRLGACQMVMCGTGMQRSTLSVSLEQAAILARSHGLLPKCIMQ
1160 1170 1180 1190 1200 1210
1570 1580 1590 1600
pF1KE3 ATDVMRKQGARVQNTAKNLGVRDRTPQSAPRLYKLCEPPPPAGEE
:::.::::: ::. :::: :.:. ::.:::::.::.::
XP_011 ATDIMRKQGPRVEILAKNLRVKDQMPQGAPRLYRLCQPPVDGDL
1220 1230 1240 1250
>>XP_005263745 (OMIM: 605216) PREDICTED: rho guanine nuc (483 aa)
initn: 495 init1: 259 opt: 675 Z-score: 544.2 bits: 111.8 E(85289): 1.4e-23
Smith-Waterman score: 768; 34.4% identity (62.7% similar) in 418 aa overlap (2-411:63-441)
10 20 30
pF1KE3 MSEDSRGDSRAESAKDLEKQLRLRVCVLSEL
.:: : ..:.:.:: ..:. :..:.
XP_005 EGWFPASFVRLRVNQDEPADDDAPLAGNSGAED--GGAEAQSSKD-----QMRTNVINEI
40 50 60 70 80
40 50 60 70 80 90
pF1KE3 QKTERDYVGTLEFLVSAFLHRMNQCAASKVDKNVTEETVKMLFSNIEDILAVHKEFLKVV
.:::::. :. . .... :: : .:: .. .:.::::: .: :.:..
XP_005 LSTERDYIKHLRDICEGYVR---QC--RKRADMFSEEQLRTIFGNIEDIYRCQKAFVKAL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE3 EECLHPEPNAQQEVGTCFLHFKDKFRIYDEYCSNHEKAQKLLLELNKIRTIRTFLLNCML
:. .. : .:.:.:::. . :.::.:::.:: .: : .:.:. :. : :
XP_005 EQRFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRLTKLSKYVYFFEACRL
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE3 LGGRKNTDVPLEGYLVTPIQRICKYPLILKELLKRTPRKHSDYAAVMEALQAMKAVCSNI
: .: :. :.:.:.::.:.:::::: : :::: : .: :. : ::.::: : . :
XP_005 L--QKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLI
210 220 230 240 250
220 230 240 250 260
pF1KE3 NEAKRQMEKLEVLEEWQSHIEGWEGSNITDTCTEMLMCGVLLKISSGNI--QERVFFLFD
:: ::..:... . .::: :: ::: .. .:... : : .... . :.:.:::::
XP_005 NERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIYSGELTRVTQPQAKSQQRMFFLFD
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE3 NLLVYCKRKHRRLKNSKASTDGHRYLFRGRINTEVMEVENVDDGTA-DFHSSGHIVVNGW
. :.:::. : : : .::.. . .:: ...:: :.: : . :..
XP_005 HQLIYCKKDLLR-------RDVLYY--KGRLDMDGLEVVDLEDGKDRDLHVS---IKNAF
320 330 340 350 360
330 340 350 360 370 380
pF1KE3 KIHNTAKNKWFVCMAKTPEEKHEWFEAILKERERRKGLKLGMEQDTWVMISEQGEKLYKM
..: : . . .. ::.:..:..:. .::: .. ..:.: :.:
XP_005 RLHRGATGDSHLLCTRKPEQKQRWLKAFARERE-----QVQLDQETGFSITE--------
370 380 390 400 410
390 400 410 420 430 440
pF1KE3 MCRQGNLIKDRKRKLTTFPK-----CFLGSEFVSWLLEIGEIHRPEEGVHLGQALLENGI
. :. ... :...: :: :.:
XP_005 LQRKQAMLNASKQQVTGKPKAVGRPCYLTRQKHPALPSNRPQQQVLVLAEPRRKPSTFWH
420 430 440 450 460 470
>>XP_005263746 (OMIM: 605216) PREDICTED: rho guanine nuc (483 aa)
initn: 495 init1: 259 opt: 675 Z-score: 544.2 bits: 111.8 E(85289): 1.4e-23
Smith-Waterman score: 768; 34.4% identity (62.7% similar) in 418 aa overlap (2-411:63-441)
10 20 30
pF1KE3 MSEDSRGDSRAESAKDLEKQLRLRVCVLSEL
.:: : ..:.:.:: ..:. :..:.
XP_005 EGWFPASFVRLRVNQDEPADDDAPLAGNSGAED--GGAEAQSSKD-----QMRTNVINEI
40 50 60 70 80
40 50 60 70 80 90
pF1KE3 QKTERDYVGTLEFLVSAFLHRMNQCAASKVDKNVTEETVKMLFSNIEDILAVHKEFLKVV
.:::::. :. . .... :: : .:: .. .:.::::: .: :.:..
XP_005 LSTERDYIKHLRDICEGYVR---QC--RKRADMFSEEQLRTIFGNIEDIYRCQKAFVKAL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE3 EECLHPEPNAQQEVGTCFLHFKDKFRIYDEYCSNHEKAQKLLLELNKIRTIRTFLLNCML
:. .. : .:.:.:::. . :.::.:::.:: .: : .:.:. :. : :
XP_005 EQRFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRLTKLSKYVYFFEACRL
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE3 LGGRKNTDVPLEGYLVTPIQRICKYPLILKELLKRTPRKHSDYAAVMEALQAMKAVCSNI
: .: :. :.:.:.::.:.:::::: : :::: : .: :. : ::.::: : . :
XP_005 L--QKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLI
210 220 230 240 250
220 230 240 250 260
pF1KE3 NEAKRQMEKLEVLEEWQSHIEGWEGSNITDTCTEMLMCGVLLKISSGNI--QERVFFLFD
:: ::..:... . .::: :: ::: .. .:... : : .... . :.:.:::::
XP_005 NERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIYSGELTRVTQPQAKSQQRMFFLFD
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE3 NLLVYCKRKHRRLKNSKASTDGHRYLFRGRINTEVMEVENVDDGTA-DFHSSGHIVVNGW
. :.:::. : : : .::.. . .:: ...:: :.: : . :..
XP_005 HQLIYCKKDLLR-------RDVLYY--KGRLDMDGLEVVDLEDGKDRDLHVS---IKNAF
320 330 340 350 360
330 340 350 360 370 380
pF1KE3 KIHNTAKNKWFVCMAKTPEEKHEWFEAILKERERRKGLKLGMEQDTWVMISEQGEKLYKM
..: : . . .. ::.:..:..:. .::: .. ..:.: :.:
XP_005 RLHRGATGDSHLLCTRKPEQKQRWLKAFARERE-----QVQLDQETGFSITE--------
370 380 390 400 410
390 400 410 420 430 440
pF1KE3 MCRQGNLIKDRKRKLTTFPK-----CFLGSEFVSWLLEIGEIHRPEEGVHLGQALLENGI
. :. ... :...: :: :.:
XP_005 LQRKQAMLNASKQQVTGKPKAVGRPCYLTRQKHPALPSNRPQQQVLVLAEPRRKPSTFWH
420 430 440 450 460 470
>>XP_011509579 (OMIM: 605216) PREDICTED: rho guanine nuc (483 aa)
initn: 495 init1: 259 opt: 675 Z-score: 544.2 bits: 111.8 E(85289): 1.4e-23
Smith-Waterman score: 768; 34.4% identity (62.7% similar) in 418 aa overlap (2-411:63-441)
10 20 30
pF1KE3 MSEDSRGDSRAESAKDLEKQLRLRVCVLSEL
.:: : ..:.:.:: ..:. :..:.
XP_011 EGWFPASFVRLRVNQDEPADDDAPLAGNSGAED--GGAEAQSSKD-----QMRTNVINEI
40 50 60 70 80
40 50 60 70 80 90
pF1KE3 QKTERDYVGTLEFLVSAFLHRMNQCAASKVDKNVTEETVKMLFSNIEDILAVHKEFLKVV
.:::::. :. . .... :: : .:: .. .:.::::: .: :.:..
XP_011 LSTERDYIKHLRDICEGYVR---QC--RKRADMFSEEQLRTIFGNIEDIYRCQKAFVKAL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE3 EECLHPEPNAQQEVGTCFLHFKDKFRIYDEYCSNHEKAQKLLLELNKIRTIRTFLLNCML
:. .. : .:.:.:::. . :.::.:::.:: .: : .:.:. :. : :
XP_011 EQRFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRLTKLSKYVYFFEACRL
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE3 LGGRKNTDVPLEGYLVTPIQRICKYPLILKELLKRTPRKHSDYAAVMEALQAMKAVCSNI
: .: :. :.:.:.::.:.:::::: : :::: : .: :. : ::.::: : . :
XP_011 L--QKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLI
210 220 230 240 250
220 230 240 250 260
pF1KE3 NEAKRQMEKLEVLEEWQSHIEGWEGSNITDTCTEMLMCGVLLKISSGNI--QERVFFLFD
:: ::..:... . .::: :: ::: .. .:... : : .... . :.:.:::::
XP_011 NERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIYSGELTRVTQPQAKSQQRMFFLFD
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE3 NLLVYCKRKHRRLKNSKASTDGHRYLFRGRINTEVMEVENVDDGTA-DFHSSGHIVVNGW
. :.:::. : : : .::.. . .:: ...:: :.: : . :..
XP_011 HQLIYCKKDLLR-------RDVLYY--KGRLDMDGLEVVDLEDGKDRDLHVS---IKNAF
320 330 340 350 360
330 340 350 360 370 380
pF1KE3 KIHNTAKNKWFVCMAKTPEEKHEWFEAILKERERRKGLKLGMEQDTWVMISEQGEKLYKM
..: : . . .. ::.:..:..:. .::: .. ..:.: :.:
XP_011 RLHRGATGDSHLLCTRKPEQKQRWLKAFARERE-----QVQLDQETGFSITE--------
370 380 390 400 410
390 400 410 420 430 440
pF1KE3 MCRQGNLIKDRKRKLTTFPK-----CFLGSEFVSWLLEIGEIHRPEEGVHLGQALLENGI
. :. ... :...: :: :.:
XP_011 LQRKQAMLNASKQQVTGKPKAVGRPCYLTRQKHPALPSNRPQQQVLVLAEPRRKPSTFWH
420 430 440 450 460 470
>>XP_011509578 (OMIM: 605216) PREDICTED: rho guanine nuc (483 aa)
initn: 495 init1: 259 opt: 675 Z-score: 544.2 bits: 111.8 E(85289): 1.4e-23
Smith-Waterman score: 768; 34.4% identity (62.7% similar) in 418 aa overlap (2-411:63-441)
10 20 30
pF1KE3 MSEDSRGDSRAESAKDLEKQLRLRVCVLSEL
.:: : ..:.:.:: ..:. :..:.
XP_011 EGWFPASFVRLRVNQDEPADDDAPLAGNSGAED--GGAEAQSSKD-----QMRTNVINEI
40 50 60 70 80
40 50 60 70 80 90
pF1KE3 QKTERDYVGTLEFLVSAFLHRMNQCAASKVDKNVTEETVKMLFSNIEDILAVHKEFLKVV
.:::::. :. . .... :: : .:: .. .:.::::: .: :.:..
XP_011 LSTERDYIKHLRDICEGYVR---QC--RKRADMFSEEQLRTIFGNIEDIYRCQKAFVKAL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE3 EECLHPEPNAQQEVGTCFLHFKDKFRIYDEYCSNHEKAQKLLLELNKIRTIRTFLLNCML
:. .. : .:.:.:::. . :.::.:::.:: .: : .:.:. :. : :
XP_011 EQRFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRLTKLSKYVYFFEACRL
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE3 LGGRKNTDVPLEGYLVTPIQRICKYPLILKELLKRTPRKHSDYAAVMEALQAMKAVCSNI
: .: :. :.:.:.::.:.:::::: : :::: : .: :. : ::.::: : . :
XP_011 L--QKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLI
210 220 230 240 250
220 230 240 250 260
pF1KE3 NEAKRQMEKLEVLEEWQSHIEGWEGSNITDTCTEMLMCGVLLKISSGNI--QERVFFLFD
:: ::..:... . .::: :: ::: .. .:... : : .... . :.:.:::::
XP_011 NERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIYSGELTRVTQPQAKSQQRMFFLFD
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE3 NLLVYCKRKHRRLKNSKASTDGHRYLFRGRINTEVMEVENVDDGTA-DFHSSGHIVVNGW
. :.:::. : : : .::.. . .:: ...:: :.: : . :..
XP_011 HQLIYCKKDLLR-------RDVLYY--KGRLDMDGLEVVDLEDGKDRDLHVS---IKNAF
320 330 340 350 360
330 340 350 360 370 380
pF1KE3 KIHNTAKNKWFVCMAKTPEEKHEWFEAILKERERRKGLKLGMEQDTWVMISEQGEKLYKM
..: : . . .. ::.:..:..:. .::: .. ..:.: :.:
XP_011 RLHRGATGDSHLLCTRKPEQKQRWLKAFARERE-----QVQLDQETGFSITE--------
370 380 390 400 410
390 400 410 420 430 440
pF1KE3 MCRQGNLIKDRKRKLTTFPK-----CFLGSEFVSWLLEIGEIHRPEEGVHLGQALLENGI
. :. ... :...: :: :.:
XP_011 LQRKQAMLNASKQQVTGKPKAVGRPCYLTRQKHPALPSNRPQQQVLVLAEPRRKPSTFWH
420 430 440 450 460 470
>>XP_005263744 (OMIM: 605216) PREDICTED: rho guanine nuc (567 aa)
initn: 495 init1: 259 opt: 675 Z-score: 543.3 bits: 111.9 E(85289): 1.6e-23
Smith-Waterman score: 768; 34.4% identity (62.7% similar) in 418 aa overlap (2-411:147-525)
10 20 30
pF1KE3 MSEDSRGDSRAESAKDLEKQLRLRVCVLSEL
.:: : ..:.:.:: ..:. :..:.
XP_005 EGWFPASFVRLRVNQDEPADDDAPLAGNSGAED--GGAEAQSSKD-----QMRTNVINEI
120 130 140 150 160
40 50 60 70 80 90
pF1KE3 QKTERDYVGTLEFLVSAFLHRMNQCAASKVDKNVTEETVKMLFSNIEDILAVHKEFLKVV
.:::::. :. . .... :: : .:: .. .:.::::: .: :.:..
XP_005 LSTERDYIKHLRDICEGYVR---QC--RKRADMFSEEQLRTIFGNIEDIYRCQKAFVKAL
170 180 190 200 210 220
100 110 120 130 140 150
pF1KE3 EECLHPEPNAQQEVGTCFLHFKDKFRIYDEYCSNHEKAQKLLLELNKIRTIRTFLLNCML
:. .. : .:.:.:::. . :.::.:::.:: .: : .:.:. :. : :
XP_005 EQRFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRLTKLSKYVYFFEACRL
230 240 250 260 270 280
160 170 180 190 200 210
pF1KE3 LGGRKNTDVPLEGYLVTPIQRICKYPLILKELLKRTPRKHSDYAAVMEALQAMKAVCSNI
: .: :. :.:.:.::.:.:::::: : :::: : .: :. : ::.::: : . :
XP_005 L--QKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLI
290 300 310 320 330 340
220 230 240 250 260
pF1KE3 NEAKRQMEKLEVLEEWQSHIEGWEGSNITDTCTEMLMCGVLLKISSGNI--QERVFFLFD
:: ::..:... . .::: :: ::: .. .:... : : .... . :.:.:::::
XP_005 NERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIYSGELTRVTQPQAKSQQRMFFLFD
350 360 370 380 390 400
270 280 290 300 310 320
pF1KE3 NLLVYCKRKHRRLKNSKASTDGHRYLFRGRINTEVMEVENVDDGTA-DFHSSGHIVVNGW
. :.:::. : : : .::.. . .:: ...:: :.: : . :..
XP_005 HQLIYCKKDLLR-------RDVLYY--KGRLDMDGLEVVDLEDGKDRDLHVS---IKNAF
410 420 430 440 450
330 340 350 360 370 380
pF1KE3 KIHNTAKNKWFVCMAKTPEEKHEWFEAILKERERRKGLKLGMEQDTWVMISEQGEKLYKM
..: : . . .. ::.:..:..:. .::: .. ..:.: :.:
XP_005 RLHRGATGDSHLLCTRKPEQKQRWLKAFARERE-----QVQLDQETGFSITE--------
460 470 480 490
390 400 410 420 430 440
pF1KE3 MCRQGNLIKDRKRKLTTFPK-----CFLGSEFVSWLLEIGEIHRPEEGVHLGQALLENGI
. :. ... :...: :: :.:
XP_005 LQRKQAMLNASKQQVTGKPKAVGRPCYLTRQKHPALPSNRPQQQVLVLAEPRRKPSTFWH
500 510 520 530 540 550
1606 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 19:29:11 2016 done: Mon Nov 7 19:29:13 2016
Total Scan time: 17.570 Total Display time: 0.450
Function used was FASTA [36.3.4 Apr, 2011]