Result of FASTA (ccds) for
pFN21AB0472
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB0472, 993 aa
1>>>pF1KB0472 993 - 993 aa - 993 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.2898+/-0.00107; mu= 5.4211+/- 0.065
mean_var=225.3272+/-44.868, 0's: 0 Z-trim(111.7): 23 B-trim: 82 in 2/49
Lambda= 0.085441
statistics sampled from 12579 (12597) to 12579 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.387), width: 16
Scan time: 4.610
The best scores are: opt bits E(32554)
CCDS8187.1 IGHMBP2 gene_id:3508|Hs108|chr11 ( 993) 6438 807.1 0
CCDS12386.1 UPF1 gene_id:5976|Hs108|chr19 (1118) 496 74.7 1.2e-12
CCDS74315.1 UPF1 gene_id:5976|Hs108|chr19 (1129) 496 74.7 1.2e-12
>>CCDS8187.1 IGHMBP2 gene_id:3508|Hs108|chr11 (993 aa)
initn: 6438 init1: 6438 opt: 6438 Z-score: 4300.0 bits: 807.1 E(32554): 0
Smith-Waterman score: 6438; 99.8% identity (99.9% similar) in 993 aa overlap (1-993:1-993)
10 20 30 40 50 60
pF1KB0 MASAAVESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKLQVSSQRTGLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 MASAAVESFVTKQLDLLELERDAEVEERRSWQENISLKELQSRGVCLLKLQVSSQRTGLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB0 GRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVTVAFDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 GRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVTVAFDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB0 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSAPSPAS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB0 EIHPLTFFNTCLDTSQKEAVSFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC
:::::::::::::::::::: :::::::::::::::::::::::::::::::::::::::
CCDS81 EIHPLTFFNTCLDTSQKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLKVLC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB0 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 CAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSAQIVADIRKDI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB0 DQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 DQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLATNTGASADGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB0 LKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 LKLLPESYFDVVVIDECAQALEASCWIPLLKARKCILAGDHKQLPPTTVSHKAALAGLSL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB0 SLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 SLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVARHLLRDLPGVAA
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB0 TEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 TEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQALVDAGVPARDIAVVSP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB0 YNLQVDLLRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 YNLQVDLLRQSLVHRHPELEIKSVDGFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB0 VTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB0 HAATKPQGPAASTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGV
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 HAATKPQGPATSTRTGSQRQEGGQEAAAPARQGRKKPAGKSLASEAPSQPSLNGGSPEGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB0 ESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 ESQDGVDHFRAMIVEFMASKKMQLEFPPSLNSHDRLRVHQIAEEHGLRHDSSGEGKRRFI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB0 TVSKRAPRPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 TVSKRAPRPRAALGPPAGTGGPAPLQPVPPTPAQTEQPPREQRGPDQPDLRTLHLERLQR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB0 VRSAQGQPASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 VRSAQGQPASKEQQASGQQKLPEKKKKKAKGHPATDLPTEEDFEALVSAAVKADNTCGFA
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB0 KCTAGVTTLGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS81 KCTAGVTTLGQFCQLCSRRYCLSHHLPEIHGCGERARAHARQRISREGVLYAGSGTKNGS
910 920 930 940 950 960
970 980 990
pF1KB0 LDPAKRAQLQRRLDKKLSELSNQRTSRRKERGT
:::::::::::::::::::::::::::::::::
CCDS81 LDPAKRAQLQRRLDKKLSELSNQRTSRRKERGT
970 980 990
>>CCDS12386.1 UPF1 gene_id:5976|Hs108|chr19 (1118 aa)
initn: 382 init1: 221 opt: 496 Z-score: 340.8 bits: 74.7 E(32554): 1.2e-12
Smith-Waterman score: 690; 29.8% identity (58.8% similar) in 638 aa overlap (17-633:312-895)
10 20 30 40
pF1KB0 MASAAVESFVTKQLDLLELERDAEVEERRSWQENISLKE---LQSR
:: . : ...: .. :.::... :...
CCDS12 KPGVDEEPQHVLLRYEDAYQYQNIFGPLVKLEADYDKKLKESQT-QDNITVRWDLGLNKK
290 300 310 320 330 340
50 60 70 80 90 100
pF1KB0 GVCLLKL-QVSSQRTGLYGRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLA
. . : ...:. . : . : :. : : .. : .. . : : :...:
CCDS12 RIAYFTLPKTDSDMRLMQGDEICL---RYKGDLAPLWKGI---GHVIKVPD--NYGDEIA
350 360 370 380 390
110 120 130 140 150 160
pF1KB0 TGILTRVTQKSVTVAFDESHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGP
. ..:: . . .:.::... . ..... :...:: .. ...
CCDS12 IEL-----RSSVGAPVEVTHNFQVDF----------VWKSTSFDRMQSALKTFAVDETSV
400 410 420 430
170 180 190 200 210
pF1KB0 ASSLIEVLFGRSAPSPASEIH-PLTFFNTCL---DTSQKEAVSFALSQKELAIIHGPPGT
.. . . :.:. . . . . : : : . :: ::. .: :. :..:.:::::
CCDS12 SGYIYHKLLGHEVEDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVL-QRPLSLIQGPPGT
440 450 460 470 480 490
220 230 240 250 260 270
pF1KB0 GKTTTVVEIILQAVKQGL-KVLCCAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQ
:::.: . :. . ..:: :: :::::::::.:.:.. ...:: .: :.:.
CCDS12 GKTVTSATIVYHLARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSR--EAID-
500 510 520 530 540 550
280 290 300 310 320 330
pF1KB0 HSLDAVLARSDSAQIVADIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAA
: . :: . :: ...:.. .: : : : ... . . . ::. :
CCDS12 -SPVSFLALHN--QI-----RNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAER-
560 570 580 590 600
340 350 360 370 380 390
pF1KB0 MLESLTSANVVLATNTGASADGPLKLLPESYFDVVVIDECAQALEASCWIPL-LKARKCI
: : .:.:. : .:: : .: . : ..::: .:: : : .:. : :.. :
CCDS12 --ELLMNADVICCTCVGA---GDPRL-AKMQFRSILIDESTQATEPECMVPVVLGAKQLI
610 620 630 640 650
400 410 420 430 440 450
pF1KB0 LAGDHKQLPPTTVSHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTM
:.::: :: :... .::: :::: ::.:::. : : .: : :::::: :. . :. .
CCDS12 LVGDHCQLGPVVMCKKAAKAGLSQSLFERLVV-LGIRPIR-LQVQYRMHPALSAFPSNIF
660 670 680 690 700 710
460 470 480 490 500 510
pF1KB0 YLGQLTAHSSVARHLLRDLPGVAATEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVR
: :.: ..: .. . . . :... : : .:. :.:. :
CCDS12 YEGSLQNGVTAADRVKKGFD--FQWPQPDKPMFFYVTQG-------QEEIASSGTSYLNR
720 730 740 750 760
520 530 540 550 560
pF1KB0 LVSLHIQA----LVDAGVPARDIAVVSPYNLQVDLLRQSL-----VHR--HPELEIKSVD
. ... :. ::. .:....::. : . : : . .: . :.:: :::
CCDS12 TEAANVEKITTKLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVD
770 780 790 800 810 820
570 580 590 600 610 620
pF1KB0 GFQGREKEAVILSFVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAFLKT
.::::::. .::: ::.:.. .::: . ::.:::.:::: : .. . ...... . .
CCDS12 AFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNH
830 840 850 860 870 880
630 640 650 660 670 680
pF1KB0 LVEYFTQHGEVRTAFEYLDDIVPENYSHENSQGSSHAATKPQGPAASTRTGSQRQEGGQE
:..:. ..
CCDS12 LLNYYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAIIPGSVY
890 900 910 920 930 940
>>CCDS74315.1 UPF1 gene_id:5976|Hs108|chr19 (1129 aa)
initn: 382 init1: 221 opt: 496 Z-score: 340.7 bits: 74.7 E(32554): 1.2e-12
Smith-Waterman score: 681; 31.0% identity (59.5% similar) in 565 aa overlap (86-633:389-906)
60 70 80 90 100 110
pF1KB0 RTGLYGRLLVTFEPRRYGSAAALPSNSFTSGDIVGLYDAANEGSQLATGILTRVTQKSVT
: .. . : : :...: . ..::
CCDS74 IIWLRDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPD--NYGDEIAIEL-----RSSVG
360 370 380 390 400 410
120 130 140 150 160 170
pF1KB0 VAFDESHDFQLSLDRENSYRLLKLANDVTYRRLKKALIALKKYHSGPASSLIEVLFGRSA
. . .:.::... . ..... :...:: .. ... .. . . :.:. .
CCDS74 APVEVTHNFQVDF----------VWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEV
420 430 440 450 460
180 190 200 210 220 230
pF1KB0 PSPASEIH-PLTFFNTCL---DTSQKEAVSFALSQKELAIIHGPPGTGKTTTVVEIILQA
. . . : : : . :: ::. .: :. :..:.::::::::.: . :. .
CCDS74 EDVIIKCQLPKRFTAQGLPDLNHSQVYAVKTVL-QRPLSLIQGPPGTGKTVTSATIVYHL
470 480 490 500 510 520
240 250 260 270 280 290
pF1KB0 VKQGL-KVLCCAPSNIAVDNLVERLALCKQRILRLGHPARLLESIQQHSLDAVLARSDSA
..:: :: :::::::::.:.:.. ...:: .: :.:. : . :: .
CCDS74 ARQGNGPVLVCAPSNIAVDQLTEKIHQTGLKVVRLCAKSR--EAID--SPVSFLALHN--
530 540 550 560 570
300 310 320 330 340 350
pF1KB0 QIVADIRKDIDQVFVKNKKTQDKREKSNFRNEIKLLRKELKEREEAAMLESLTSANVVLA
:: ...:.. .: : : : ... . . . ::. : : : .:.:.
CCDS74 QI-----RNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAER---ELLMNADVICC
580 590 600 610 620
360 370 380 390 400
pF1KB0 TNTGASADGPLKLLPESYFDVVVIDECAQALEASCWIPL-LKARKCILAGDHKQLPPTTV
: .:: : .: . : ..::: .:: : : .:. : :.. ::.::: :: :...
CCDS74 TCVGA---GDPRL-AKMQFRSILIDESTQATEPECMVPVVLGAKQLILVGDHCQLGPVVM
630 640 650 660 670 680
410 420 430 440 450 460
pF1KB0 SHKAALAGLSLSLMERLAEEYGARVVRTLTVQYRMHQAIMRWASDTMYLGQLTAHSSVAR
.::: :::: ::.:::. : : .: : :::::: :. . :. .: :.: ..:
CCDS74 CKKAAKAGLSQSLFERLVV-LGIRPIR-LQVQYRMHPALSAFPSNIFYEGSLQNGVTAAD
690 700 710 720 730 740
470 480 490 500 510 520
pF1KB0 HLLRDLPGVAATEETGVPLLLVDTAGCGLFELEEEDEQSKGNPGEVRLVSLHIQA----L
.. . . . :... : : .:. :.:. : . ... :
CCDS74 RVKKGFD--FQWPQPDKPMFFYVTQG-------QEEIASSGTSYLNRTEAANVEKITTKL
750 760 770 780 790
530 540 550 560 570
pF1KB0 VDAGVPARDIAVVSPYNLQVDLLRQSL-----VHR--HPELEIKSVDGFQGREKEAVILS
. ::. .:....::. : . : : . .: . :.:: :::.::::::. .:::
CCDS74 LKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQEVEIASVDAFQGREKDFIILS
800 810 820 830 840 850
580 590 600 610 620 630
pF1KB0 FVRSNRKGEVGFLAEDRRINVAVTRARRHVAVICDSRTVNNHAFLKTLVEYFTQHGEVRT
::.:.. .::: . ::.:::.:::: : .. . ...... . . :..:. ..
CCDS74 CVRANEHQGIGFLNDPRRLNVALTRARYGVIIVGNPKALSKQPLWNHLLNYYKEQKVLVE
860 870 880 890 900 910
640 650 660 670 680 690
pF1KB0 AFEYLDDIVPENYSHENSQGSSHAATKPQGPAASTRTGSQRQEGGQEAAAPARQGRKKPA
CCDS74 GPLNNLRESLMQFSKPRKLVNTINPGARFMTTAMYDAREAIIPGSVYDRSSQGRPSSMYF
920 930 940 950 960 970
993 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 18:50:15 2016 done: Mon Nov 7 18:50:16 2016
Total Scan time: 4.610 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]