Result of FASTA (omim) for
pFN21AE3393
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3393, 1188 aa
1>>>pF1KE3393 1188 - 1188 aa - 1188 aa
Library: /omim/omim.rfq.tfa
63214209 residues in 88908 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.3074+/-0.000493; mu= -0.9575+/- 0.031
mean_var=298.4263+/-60.138, 0's: 0 Z-trim(118.3): 110 B-trim: 856 in 2/55
Lambda= 0.074243
statistics sampled from 31707 (31840) to 31707 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.358), width: 16
Scan time: 14.890
The best scores are: opt bits E(88908)
NP_075377 (OMIM: 180201) AT-rich interactive domai (1188) 7675 837.1 0
NP_075376 (OMIM: 180201) AT-rich interactive domai (1203) 7159 781.8 0
NP_002883 (OMIM: 180201) AT-rich interactive domai (1257) 7153 781.2 0
XP_016877051 (OMIM: 180201) PREDICTED: AT-rich int (1264) 7129 778.6 0
XP_016877054 (OMIM: 180201) PREDICTED: AT-rich int ( 935) 5081 559.2 4.6e-158
XP_005268022 (OMIM: 180201) PREDICTED: AT-rich int (1208) 4552 502.6 6.4e-141
XP_016877052 (OMIM: 180201) PREDICTED: AT-rich int (1215) 4552 502.6 6.5e-141
XP_005268021 (OMIM: 180201) PREDICTED: AT-rich int (1277) 4552 502.6 6.7e-141
XP_016877049 (OMIM: 180201) PREDICTED: AT-rich int (1284) 4552 502.6 6.7e-141
XP_016877050 (OMIM: 180201) PREDICTED: AT-rich int (1284) 4552 502.6 6.7e-141
XP_016877053 (OMIM: 180201) PREDICTED: AT-rich int (1137) 3588 399.3 7.4e-110
XP_011542514 (OMIM: 609696) PREDICTED: AT-rich int (1312) 2442 276.6 7.4e-73
NP_057458 (OMIM: 609696) AT-rich interactive domai (1312) 2442 276.6 7.4e-73
NP_001193723 (OMIM: 609696) AT-rich interactive do (1312) 2442 276.6 7.4e-73
XP_016856957 (OMIM: 609696) PREDICTED: AT-rich int (1314) 2429 275.2 1.9e-72
XP_006711844 (OMIM: 609696) PREDICTED: AT-rich int (1276) 2224 253.3 7.7e-66
XP_016856958 (OMIM: 609696) PREDICTED: AT-rich int (1278) 2211 251.9 2e-65
NP_112739 (OMIM: 609696) AT-rich interactive domai (1226) 1937 222.5 1.3e-56
XP_016856959 (OMIM: 609696) PREDICTED: AT-rich int (1228) 1924 221.1 3.5e-56
XP_016856960 (OMIM: 609696) PREDICTED: AT-rich int (1057) 1917 220.3 5.3e-56
XP_016856961 (OMIM: 609696) PREDICTED: AT-rich int (1019) 1204 143.9 5e-33
NP_006456 (OMIM: 612457) AT-rich interactive domai ( 560) 288 45.6 0.0011
NP_001294868 (OMIM: 612457) AT-rich interactive do ( 561) 288 45.6 0.0011
XP_011538564 (OMIM: 608538) PREDICTED: AT-rich int (1111) 276 44.6 0.0045
NP_001231567 (OMIM: 608538) AT-rich interactive do ( 945) 266 43.4 0.0083
NP_115575 (OMIM: 608538) AT-rich interactive domai (1188) 266 43.5 0.0099
>>NP_075377 (OMIM: 180201) AT-rich interactive domain-co (1188 aa)
initn: 7675 init1: 7675 opt: 7675 Z-score: 4459.1 bits: 837.1 E(88908): 0
Smith-Waterman score: 7675; 100.0% identity (100.0% similar) in 1188 aa overlap (1-1188:1-1188)
10 20 30 40 50 60
pF1KE3 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 LEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 EQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 EQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 EVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 EVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 SESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 SESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 GLMAKKQKRTPKRTSAAAKNEKNGTDELDNMNSTERISFLQEKLQEIRKYYMSLKSEVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 GLMAKKQKRTPKRTSAAAKNEKNGTDELDNMNSTERISFLQEKLQEIRKYYMSLKSEVAT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180
pF1KE3 IDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVECR
::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 IDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVECR
1150 1160 1170 1180
>>NP_075376 (OMIM: 180201) AT-rich interactive domain-co (1203 aa)
initn: 7245 init1: 7153 opt: 7159 Z-score: 4160.4 bits: 781.8 E(88908): 0
Smith-Waterman score: 7629; 98.7% identity (98.8% similar) in 1203 aa overlap (1-1188:1-1203)
10 20 30 40 50 60
pF1KE3 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 LEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 EQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 EQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 EVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 EVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 SESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 SESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120
pF1KE3 GLMAKKQKRTPKRTSAAAKNEKNGT---------------DELDNMNSTERISFLQEKLQ
::::::::::::::::::::::::: .:::::::::::::::::::
NP_075 GLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNSNELDNMNSTERISFLQEKLQ
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KE3 EIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 EIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAV
1150 1160 1170 1180 1190 1200
pF1KE3 ECR
:::
NP_075 ECR
>>NP_002883 (OMIM: 180201) AT-rich interactive domain-co (1257 aa)
initn: 7153 init1: 7153 opt: 7153 Z-score: 4156.6 bits: 781.2 E(88908): 0
Smith-Waterman score: 7282; 94.3% identity (94.3% similar) in 1220 aa overlap (1-1151:1-1220)
10 20 30 40 50 60
pF1KE3 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 EQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 EVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 SESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQKRPSDGNS
1030 1040 1050 1060 1070 1080
1090 1100
pF1KE3 GLMAKKQKRTPKRTSAAAKNEKNGT-----------------------------------
:::::::::::::::::::::::::
NP_002 GLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNSSKCTPVKHLNVSKPQKLARS
1090 1100 1110 1120 1130 1140
1110 1120 1130
pF1KE3 ----------------------------------DELDNMNSTERISFLQEKLQEIRKYY
.:::::::::::::::::::::::::
NP_002 PARISPHIKDGEKDKHREKHPNSSPRTYKWSFQLNELDNMNSTERISFLQEKLQEIRKYY
1150 1160 1170 1180 1190 1200
1140 1150 1160 1170 1180
pF1KE3 MSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVECR
::::::::::::::::::::
NP_002 MSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVECR
1210 1220 1230 1240 1250
>>XP_016877051 (OMIM: 180201) PREDICTED: AT-rich interac (1264 aa)
initn: 7498 init1: 6936 opt: 7129 Z-score: 4142.7 bits: 778.6 E(88908): 0
Smith-Waterman score: 7215; 93.7% identity (93.8% similar) in 1220 aa overlap (1-1144:1-1220)
10 20 30 40 50 60
pF1KE3 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGNKMEKTE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSSLDNKNFSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGSEGMKNLNF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 EQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLIGPETLVCH
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 EVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLSQDESRSVK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KE3 SESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKG-------QK
::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 SESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGKDFLGKSQK
1030 1040 1050 1060 1070 1080
1080 1090 1100
pF1KE3 RPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGT----------------------------
::::::::::::::::::::::::::::::::
XP_016 RPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNSSKCTPVKHLNVSK
1090 1100 1110 1120 1130 1140
1110 1120
pF1KE3 -----------------------------------------DELDNMNSTERISFLQEKL
.::::::::::::::::::
XP_016 PQKLARSPARISPHIKDGEKDKHREKHPNSSPRTYKWSFQLNELDNMNSTERISFLQEKL
1150 1160 1170 1180 1190 1200
1130 1140 1150 1160 1170 1180
pF1KE3 QEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLA
::::::::::::::::::::
XP_016 QEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLA
1210 1220 1230 1240 1250 1260
>>XP_016877054 (OMIM: 180201) PREDICTED: AT-rich interac (935 aa)
initn: 5081 init1: 5081 opt: 5081 Z-score: 2959.0 bits: 559.2 E(88908): 4.6e-158
Smith-Waterman score: 5210; 92.2% identity (92.3% similar) in 898 aa overlap (323-1151:1-898)
300 310 320 330 340 350
pF1KE3 KEAKKTEEEVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYH
::::::::::::::::::::::::::::::
XP_016 MEDRGTPINKPPVLGYKDLNLFKLFRLVYH
10 20 30
360 370 380 390 400 410
pF1KE3 QGGCDNIDSGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGGCDNIDSGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHH
40 50 60 70 80 90
420 430 440 450 460 470
pF1KE3 HEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEPKVKEEKKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRR
100 110 120 130 140 150
480 490 500 510 520 530
pF1KE3 IARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IARDVNSIKKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKI
160 170 180 190 200 210
540 550 560 570 580 590
pF1KE3 KKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKQEDSDKDSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIY
220 230 240 250 260 270
600 610 620 630 640 650
pF1KE3 EASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EASIKSTEIDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSE
280 290 300 310 320 330
660 670 680 690 700 710
pF1KE3 KDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDEKRDEERQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLIN
340 350 360 370 380 390
720 730 740 750 760 770
pF1KE3 EELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIF
400 410 420 430 440 450
780 790 800 810 820 830
pF1KE3 GNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSEPHIEAHSLELSS
460 470 480 490 500 510
840 850 860 870 880 890
pF1KE3 LDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSDCIGS
520 530 540 550 560 570
900 910 920 930 940 950
pF1KE3 EGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDAMPLI
580 590 600 610 620 630
960 970 980 990 1000 1010
pF1KE3 GPETLVCHEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPETLVCHEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQHNFSVASPLTLS
640 650 660 670 680 690
1020 1030 1040 1050 1060 1070
pF1KE3 QDESRSVKSESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDESRSVKSESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSIIVQERESREKGQ
700 710 720 730 740 750
1080 1090 1100
pF1KE3 KRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGT---------------------------
:::::::::::::::::::::::::::::::::
XP_016 KRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNSSKCTPVKHLNVS
760 770 780 790 800 810
1110 1120
pF1KE3 ------------------------------------------DELDNMNSTERISFLQEK
.:::::::::::::::::
XP_016 KPQKLARSPARISPHIKDGEKDKHREKHPNSSPRTYKWSFQLNELDNMNSTERISFLQEK
820 830 840 850 860 870
1130 1140 1150 1160 1170 1180
pF1KE3 LQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVL
::::::::::::::::::::::::::::
XP_016 LQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVL
880 890 900 910 920 930
>>XP_005268022 (OMIM: 180201) PREDICTED: AT-rich interac (1208 aa)
initn: 4541 init1: 4541 opt: 4552 Z-score: 2651.2 bits: 502.6 E(88908): 6.4e-141
Smith-Waterman score: 7625; 98.3% identity (98.3% similar) in 1208 aa overlap (1-1188:1-1208)
10 20 30 40 50 60
pF1KE3 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
610 620 630 640 650 660
670 680 690 700
pF1KE3 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKS--------------------DSCSSDS
::::::::::::::::::::::::::::::::: :::::::
XP_005 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSGTRSARSNIPDSSPLSNGMEDSCSSDS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE3 ETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKL
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE3 EVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSE
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE3 PHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNT
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 VSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNI
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 PLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQ
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 HNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSI
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE3 IVQERESREKGQKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTDELDNMNSTERISFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVQERESREKGQKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTDELDNMNSTERISFL
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KE3 QEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQ
1150 1160 1170 1180 1190 1200
pF1KE3 NVLAVECR
::::::::
XP_005 NVLAVECR
>>XP_016877052 (OMIM: 180201) PREDICTED: AT-rich interac (1215 aa)
initn: 6945 init1: 4541 opt: 4552 Z-score: 2651.2 bits: 502.6 E(88908): 6.5e-141
Smith-Waterman score: 7601; 97.8% identity (97.8% similar) in 1215 aa overlap (1-1188:1-1215)
10 20 30 40 50 60
pF1KE3 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
610 620 630 640 650 660
670 680 690 700
pF1KE3 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKS--------------------DSCSSDS
::::::::::::::::::::::::::::::::: :::::::
XP_016 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSGTRSARSNIPDSSPLSNGMEDSCSSDS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE3 ETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKL
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE3 EVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSE
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE3 PHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNT
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 VSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNI
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 PLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQ
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 HNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSI
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110
pF1KE3 IVQERESREKG-------QKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTDELDNMNS
::::::::::: ::::::::::::::::::::::::::::::::::::::::::
XP_016 IVQERESREKGKDFLGKSQKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTDELDNMNS
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
pF1KE3 TERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSP
1150 1160 1170 1180 1190 1200
1180
pF1KE3 SSSSPPQNVLAVECR
:::::::::::::::
XP_016 SSSSPPQNVLAVECR
1210
>>XP_005268021 (OMIM: 180201) PREDICTED: AT-rich interac (1277 aa)
initn: 5044 init1: 4541 opt: 4552 Z-score: 2650.9 bits: 502.6 E(88908): 6.7e-141
Smith-Waterman score: 7113; 92.6% identity (92.7% similar) in 1220 aa overlap (1-1131:1-1220)
10 20 30 40 50 60
pF1KE3 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
610 620 630 640 650 660
670 680 690 700
pF1KE3 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKS--------------------DSCSSDS
::::::::::::::::::::::::::::::::: :::::::
XP_005 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSGTRSARSNIPDSSPLSNGMEDSCSSDS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE3 ETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKL
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE3 EVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSE
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE3 PHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNT
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 VSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNI
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 PLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQ
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 HNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSI
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100
pF1KE3 IVQERESREKGQKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGT---------------
:::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVQERESREKGQKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSEDLPVLDNS
1090 1100 1110 1120 1130 1140
1110
pF1KE3 ------------------------------------------------------DELDNM
.:::::
XP_005 SKCTPVKHLNVSKPQKLARSPARISPHIKDGEKDKHREKHPNSSPRTYKWSFQLNELDNM
1150 1160 1170 1180 1190 1200
1120 1130 1140 1150 1160 1170
pF1KE3 NSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGM
::::::::::::::::::::
XP_005 NSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGM
1210 1220 1230 1240 1250 1260
>--
initn: 358 init1: 358 opt: 358 Z-score: 223.1 bits: 53.4 E(88908): 1.1e-05
Smith-Waterman score: 358; 100.0% identity (100.0% similar) in 57 aa overlap (1132-1188:1221-1277)
1110 1120 1130 1140 1150 1160
pF1KE3 KNGTDELDNMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGAS
::::::::::::::::::::::::::::::
XP_005 SFQLNELDNMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGAS
1200 1210 1220 1230 1240 1250
1170 1180
pF1KE3 MSSASSDTGMSPSSSSPPQNVLAVECR
:::::::::::::::::::::::::::
XP_005 MSSASSDTGMSPSSSSPPQNVLAVECR
1260 1270
>>XP_016877049 (OMIM: 180201) PREDICTED: AT-rich interac (1284 aa)
initn: 7448 init1: 4541 opt: 4552 Z-score: 2650.9 bits: 502.6 E(88908): 6.7e-141
Smith-Waterman score: 7082; 93.6% identity (95.2% similar) in 1189 aa overlap (1-1152:1-1189)
10 20 30 40 50 60
pF1KE3 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
610 620 630 640 650 660
670 680 690 700
pF1KE3 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKS--------------------DSCSSDS
::::::::::::::::::::::::::::::::: :::::::
XP_016 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSGTRSARSNIPDSSPLSNGMEDSCSSDS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE3 ETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKL
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE3 EVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSE
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE3 PHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNT
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 VSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNI
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 PLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQ
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 HNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSI
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100
pF1KE3 IVQERESREKG-------QKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTDE------
::::::::::: :::::::::::::::::::::::::::::::::: .
XP_016 IVQERESREKGKDFLGKSQKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSED
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KE3 ---LDNMNSTERISFLQ-EKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMS
::: .. .. :. : :.. . .. .. .. ..: :. .
XP_016 LPVLDNSSKCTPVKHLNVSKPQKLARSPARISPHIKDGEKDKHREKHPNSSPRTYKWSFQ
1150 1160 1170 1180 1190 1200
1170 1180
pF1KE3 SASSDTGMSPSSSSPPQNVLAVECR
XP_016 LNELDNMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSS
1210 1220 1230 1240 1250 1260
>--
initn: 529 init1: 517 opt: 517 Z-score: 315.1 bits: 70.4 E(88908): 8.5e-11
Smith-Waterman score: 517; 98.8% identity (100.0% similar) in 83 aa overlap (1106-1188:1202-1284)
1080 1090 1100 1110 1120 1130
pF1KE3 SDGNSGLMAKKQKRTPKRTSAAAKNEKNGTDELDNMNSTERISFLQEKLQEIRKYYMSLK
.:::::::::::::::::::::::::::::
XP_016 SPHIKDGEKDKHREKHPNSSPRTYKWSFQLNELDNMNSTERISFLQEKLQEIRKYYMSLK
1180 1190 1200 1210 1220 1230
1140 1150 1160 1170 1180
pF1KE3 SEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVECR
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVECR
1240 1250 1260 1270 1280
>>XP_016877050 (OMIM: 180201) PREDICTED: AT-rich interac (1284 aa)
initn: 7448 init1: 4541 opt: 4552 Z-score: 2650.9 bits: 502.6 E(88908): 6.7e-141
Smith-Waterman score: 7082; 93.6% identity (95.2% similar) in 1189 aa overlap (1-1152:1-1189)
10 20 30 40 50 60
pF1KE3 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKAADEPAYLTVGTDVSAKYRGAFCEAKIKTVKRLVKVKVLLKQDNTTQLVQDDQVKGPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVGAIVETRTSDGSFQEAIISKLTDASWYTVVFDDGDERTLRRTSLCLKGERHFAESETL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DQLPLTNPEHFGTPVIAKKTNRGRRSSLPVTEDEKEEESSEEEDEDKRRLNDELLGKVVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVSATERTEWYPALVISPSCNDDITVKKDQCLVRSFIDSKFYSIARKDIKEVDILNLPES
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELSTKPGLQKASIFLKTRVVPDNWKMDISEILESSSSDDEDGPAEENDEEKEKEAKKTEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVPEEELDPEERDNFLQQLYKFMEDRGTPINKPPVLGYKDLNLFKLFRLVYHQGGCDNID
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGAVWKQIYMDLGIPILNSAASYNVKTAYRKYLYGFEEYCRSANIQFRTVHHHEPKVKEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKDLEESMEEALKLDQEMPLTEVKSEPEENIDSNSESEREEIELKSPRGRRRIARDVNSI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKEIEEEKTEDKLKDNDTENKDVDDDYETAEKKENELLLGRKNTPKQKEKKIKKQEDSDK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSDEEEEKSQEREETESKCDSEGEEDEEDMEPCLTGTKVKVKYGRGKTQKIYEASIKSTE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IDDGEVLYLVHYYGWNVRYDEWVKADRIIWPLDKGGPKKKQKKKAKNKEDSEKDEKRDEE
610 620 630 640 650 660
670 680 690 700
pF1KE3 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKS--------------------DSCSSDS
::::::::::::::::::::::::::::::::: :::::::
XP_016 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSGTRSARSNIPDSSPLSNGMEDSCSSDS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE3 ETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETEDALEKNLINEELSLKDELEKNENLNDDKLDEENPKISAHILKENDRTQMQPLETLKL
730 740 750 760 770 780
770 780 790 800 810 820
pF1KE3 EVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVGENEQIVQIFGNKMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEIIKISSFGQNEAGSE
790 800 810 820 830 840
830 840 850 860 870 880
pF1KE3 PHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PHIEAHSLELSSLDNKNFSSATEDEIDQCVKEKKLKRKILGQSSPEKKIRIENGMEMTNT
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 VSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSQERTSDCIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNI
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 PLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLKEDEDAMPLIGPETLVCHEVDLDDLDEKDKTSIEDVAVESSESNSLVSIPPALPPVVQ
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 HNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HNFSVASPLTLSQDESRSVKSESDITIEVDSIAEESQEGLCERESANGFETNVASGTCSI
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100
pF1KE3 IVQERESREKG-------QKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTDE------
::::::::::: :::::::::::::::::::::::::::::::::: .
XP_016 IVQERESREKGKDFLGKSQKRPSDGNSGLMAKKQKRTPKRTSAAAKNEKNGTGQSSDSED
1090 1100 1110 1120 1130 1140
1110 1120 1130 1140 1150 1160
pF1KE3 ---LDNMNSTERISFLQ-EKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMS
::: .. .. :. : :.. . .. .. .. ..: :. .
XP_016 LPVLDNSSKCTPVKHLNVSKPQKLARSPARISPHIKDGEKDKHREKHPNSSPRTYKWSFQ
1150 1160 1170 1180 1190 1200
1170 1180
pF1KE3 SASSDTGMSPSSSSPPQNVLAVECR
XP_016 LNELDNMNSTERISFLQEKLQEIRKYYMSLKSEVATIDRRRKRLKKKDREVSHAGASMSS
1210 1220 1230 1240 1250 1260
>--
initn: 529 init1: 517 opt: 517 Z-score: 315.1 bits: 70.4 E(88908): 8.5e-11
Smith-Waterman score: 517; 98.8% identity (100.0% similar) in 83 aa overlap (1106-1188:1202-1284)
1080 1090 1100 1110 1120 1130
pF1KE3 SDGNSGLMAKKQKRTPKRTSAAAKNEKNGTDELDNMNSTERISFLQEKLQEIRKYYMSLK
.:::::::::::::::::::::::::::::
XP_016 SPHIKDGEKDKHREKHPNSSPRTYKWSFQLNELDNMNSTERISFLQEKLQEIRKYYMSLK
1180 1190 1200 1210 1220 1230
1140 1150 1160 1170 1180
pF1KE3 SEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVECR
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEVATIDRRRKRLKKKDREVSHAGASMSSASSDTGMSPSSSSPPQNVLAVECR
1240 1250 1260 1270 1280
1188 residues in 1 query sequences
63214209 residues in 88908 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Sep 21 11:29:38 2017 done: Thu Sep 21 11:29:41 2017
Total Scan time: 14.890 Total Display time: 0.500
Function used was FASTA [36.3.4 Apr, 2011]