Result of FASTA (omim) for
pFN21AE0662
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0662, 387 aa
1>>>pF1KE0662 387 - 387 aa - 387 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.0904+/-0.000844; mu= -17.5556+/- 0.048
mean_var=775.2077+/-176.606, 0's: 0 Z-trim(112.6): 1608 B-trim: 0 in 0/49
Lambda= 0.046064
statistics sampled from 19572 (21610) to 19572 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.613), E-opt: 0.2 (0.253), width: 16
Scan time: 7.870
The best scores are: opt bits E(85289)
NP_006204 (OMIM: 172470) phosphorylase b kinase ga ( 387) 2583 188.0 3.2e-47
NP_001245389 (OMIM: 172470) phosphorylase b kinase ( 378) 2004 149.5 1.2e-35
XP_005271829 (OMIM: 172470) PREDICTED: phosphoryla ( 309) 1896 142.2 1.5e-33
NP_001245388 (OMIM: 172470) phosphorylase b kinase ( 419) 1891 142.1 2.3e-33
NP_000285 (OMIM: 172471,613027) phosphorylase b ki ( 406) 1717 130.5 6.9e-30
NP_001165903 (OMIM: 172471,613027) phosphorylase b ( 374) 1640 125.4 2.3e-28
XP_016867816 (OMIM: 172470) PREDICTED: phosphoryla ( 326) 1396 109.0 1.6e-23
XP_016867815 (OMIM: 172470) PREDICTED: phosphoryla ( 354) 1396 109.1 1.7e-23
XP_016867814 (OMIM: 172470) PREDICTED: phosphoryla ( 378) 1396 109.1 1.7e-23
XP_016867813 (OMIM: 172470) PREDICTED: phosphoryla ( 432) 1396 109.2 1.9e-23
NP_003647 (OMIM: 604998) calcium/calmodulin-depend ( 370) 631 58.3 3.5e-08
XP_005265573 (OMIM: 604998) PREDICTED: calcium/cal ( 413) 631 58.4 3.7e-08
NP_001339 (OMIM: 603289) death-associated protein ( 454) 627 58.2 4.7e-08
XP_005259565 (OMIM: 603289) PREDICTED: death-assoc ( 454) 627 58.2 4.7e-08
XP_016862843 (OMIM: 604998) PREDICTED: calcium/cal ( 326) 614 57.1 7.1e-08
XP_005265574 (OMIM: 604998) PREDICTED: calcium/cal ( 369) 614 57.2 7.6e-08
XP_006717546 (OMIM: 607957) PREDICTED: calcium/cal ( 355) 610 56.9 8.9e-08
NP_065130 (OMIM: 607957) calcium/calmodulin-depend ( 357) 610 56.9 8.9e-08
XP_006717545 (OMIM: 607957) PREDICTED: calcium/cal ( 362) 610 56.9 9e-08
XP_006717544 (OMIM: 607957) PREDICTED: calcium/cal ( 366) 610 56.9 9.1e-08
XP_011517893 (OMIM: 607957) PREDICTED: calcium/cal ( 372) 610 56.9 9.1e-08
NP_705718 (OMIM: 607957) calcium/calmodulin-depend ( 385) 610 56.9 9.3e-08
NP_001310304 (OMIM: 114080) calcium/calmodulin-dep ( 473) 600 56.4 1.7e-07
NP_001735 (OMIM: 114080) calcium/calmodulin-depend ( 473) 600 56.4 1.7e-07
NP_001310303 (OMIM: 114080) calcium/calmodulin-dep ( 473) 600 56.4 1.7e-07
XP_016884768 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 594 55.8 1.8e-07
XP_011529409 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 594 55.8 1.8e-07
XP_011529413 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 594 55.8 1.8e-07
XP_006724872 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 594 55.8 1.8e-07
XP_005274708 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 594 55.8 1.8e-07
XP_016884767 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 594 55.8 1.8e-07
XP_011529414 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 594 55.8 1.8e-07
XP_011529412 (OMIM: 300680) PREDICTED: calcium/cal ( 343) 594 55.8 1.8e-07
XP_016884050 (OMIM: 114480,176807,259500,604373,60 ( 322) 593 55.7 1.8e-07
XP_011528147 (OMIM: 114480,176807,259500,604373,60 ( 322) 593 55.7 1.8e-07
NP_001244316 (OMIM: 114480,176807,259500,604373,60 ( 322) 593 55.7 1.8e-07
NP_001129212 (OMIM: 300680) calcium/calmodulin-dep ( 360) 594 55.8 1.9e-07
XP_011529410 (OMIM: 300680) PREDICTED: calcium/cal ( 361) 594 55.8 1.9e-07
XP_016884766 (OMIM: 300680) PREDICTED: calcium/cal ( 426) 594 55.9 2.1e-07
NP_001034671 (OMIM: 300680) calcium/calmodulin-dep ( 426) 594 55.9 2.1e-07
XP_016857355 (OMIM: 614994) PREDICTED: calcium/cal ( 476) 595 56.1 2.1e-07
NP_065172 (OMIM: 614994) calcium/calmodulin-depend ( 476) 595 56.1 2.1e-07
NP_009125 (OMIM: 114480,176807,259500,604373,60926 ( 543) 596 56.2 2.2e-07
XP_016884049 (OMIM: 114480,176807,259500,604373,60 ( 584) 596 56.3 2.2e-07
NP_001005735 (OMIM: 114480,176807,259500,604373,60 ( 586) 596 56.3 2.2e-07
XP_011528141 (OMIM: 114480,176807,259500,604373,60 ( 596) 596 56.3 2.3e-07
XP_011532469 (OMIM: 613167) PREDICTED: serine/thre ( 648) 595 56.3 2.5e-07
NP_208382 (OMIM: 613167) serine/threonine-protein ( 648) 595 56.3 2.5e-07
XP_005251814 (OMIM: 600831) PREDICTED: death-assoc ( 839) 597 56.6 2.6e-07
XP_016877533 (OMIM: 616567) PREDICTED: death-assoc ( 350) 586 55.3 2.7e-07
>>NP_006204 (OMIM: 172470) phosphorylase b kinase gamma (387 aa)
initn: 2583 init1: 2583 opt: 2583 Z-score: 968.9 bits: 188.0 E(85289): 3.2e-47
Smith-Waterman score: 2583; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:1-387)
10 20 30 40 50 60
pF1KE0 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 TLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 LREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 MIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 PRGKFKVIALTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PRGKFKVIALTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVK
310 320 330 340 350 360
370 380
pF1KE0 KGQQQNRAALFENTPKAVLLSLAEEDY
:::::::::::::::::::::::::::
NP_006 KGQQQNRAALFENTPKAVLLSLAEEDY
370 380
>>NP_001245389 (OMIM: 172470) phosphorylase b kinase gam (378 aa)
initn: 2003 init1: 2003 opt: 2004 Z-score: 761.0 bits: 149.5 E(85289): 1.2e-35
Smith-Waterman score: 2493; 97.7% identity (97.7% similar) in 387 aa overlap (1-387:1-378)
10 20 30 40 50 60
pF1KE0 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKV
:::::::::::::::::::: :::::::::::::::::::::::::::::::
NP_001 PEEVRELREATLKEVDILRK---------LKDTYETNTFFFLVFDLMKRGELFDYLTEKV
70 80 90 100 110
130 140 150 160 170 180
pF1KE0 TLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE0 LREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE0 MIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE0 PRGKFKVIALTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRGKFKVIALTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVK
300 310 320 330 340 350
370 380
pF1KE0 KGQQQNRAALFENTPKAVLLSLAEEDY
:::::::::::::::::::::::::::
NP_001 KGQQQNRAALFENTPKAVLLSLAEEDY
360 370
>>XP_005271829 (OMIM: 172470) PREDICTED: phosphorylase b (309 aa)
initn: 1892 init1: 1892 opt: 1896 Z-score: 723.1 bits: 142.2 E(85289): 1.5e-33
Smith-Waterman score: 1916; 79.8% identity (79.8% similar) in 387 aa overlap (1-387:1-309)
10 20 30 40 50 60
pF1KE0 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFS
::::::::::::::::::::::::::::
XP_005 MTRDEALPDSHSAQDFYENYEPKEILGR--------------------------------
10 20
70 80 90 100 110 120
pF1KE0 PEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKV
::::::::::::::
XP_005 ----------------------------------------------MKRGELFDYLTEKV
30 40
130 140 150 160 170 180
pF1KE0 TLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE0 LREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLR
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE0 MIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFS
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE0 PRGKFKVIALTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRGKFKVIALTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVK
230 240 250 260 270 280
370 380
pF1KE0 KGQQQNRAALFENTPKAVLLSLAEEDY
:::::::::::::::::::::::::::
XP_005 KGQQQNRAALFENTPKAVLLSLAEEDY
290 300
>>NP_001245388 (OMIM: 172470) phosphorylase b kinase gam (419 aa)
initn: 2569 init1: 1891 opt: 1891 Z-score: 720.0 bits: 142.1 E(85289): 2.3e-33
Smith-Waterman score: 2509; 92.4% identity (92.4% similar) in 419 aa overlap (1-387:1-419)
10 20 30 40 50 60
pF1KE0 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFS
10 20 30 40 50 60
70 80 90 100
pF1KE0 PEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDL--------------
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLWEDTDTMEMEQKWC
70 80 90 100 110 120
110 120 130 140
pF1KE0 ------------------MKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLHKLNIVH
::::::::::::::::::::::::::::::::::::::::::
NP_001 LGWDSPKSTNFRAQGRARMKRGELFDYLTEKVTLSEKETRKIMRALLEVICTLHKLNIVH
130 140 150 160 170 180
150 160 170 180 190 200
pF1KE0 RDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDHPGYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDLKPENILLDDNMNIKLTDFGFSCQLEPGERLREVCGTPSYLAPEIIECSMNEDHPGYG
190 200 210 220 230 240
210 220 230 240 250 260
pF1KE0 KEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRF
250 260 270 280 290 300
270 280 290 300 310 320
pF1KE0 LVVQPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLASVRIYYQYRRVKPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVVQPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLASVRIYYQYRRVKPV
310 320 330 340 350 360
330 340 350 360 370 380
pF1KE0 TREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKAVLLSLAEEDY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKAVLLSLAEEDY
370 380 390 400 410
>>NP_000285 (OMIM: 172471,613027) phosphorylase b kinase (406 aa)
initn: 1718 init1: 1509 opt: 1717 Z-score: 657.6 bits: 130.5 E(85289): 6.9e-30
Smith-Waterman score: 1717; 64.5% identity (89.0% similar) in 372 aa overlap (4-375:8-378)
10 20 30 40 50
pF1KE0 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGG
.. ::: .:..::..:.::...:::::::::::.:. :..:.:::...::.
NP_000 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 GSFSPEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYL
.:::...:.:::: .:. :::.:.:::.:: : :.::...:.:::::::..:::::::
NP_000 -RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYL
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 TEKVTLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLE
::::.:::::::.:::.:::.. :: ::::::::::::::::::.:.:.::::::.::
NP_000 TEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 PGERLREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQM
:::.:::.::::.::::::..:::.: :::::::::.:. :::..::::::::::::.:.
NP_000 PGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQI
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 LMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEV
::::::: :.:::.:::::: :.:::::.::.: :.:. : :::.:: ::::.. .
NP_000 LMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 RHFSPRGKFKVIALTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYG
...:: .:.: . ::::. :. . .::.:.:.. ..::::::: .:.::: :::.::
NP_000 WNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYG
300 310 320 330 340 350
360 370 380
pF1KE0 HWVKKGQQQNRAALFENTPKAVLLSLAEEDY
::::::.::::::::.. :
NP_000 HWVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG
360 370 380 390 400
>>NP_001165903 (OMIM: 172471,613027) phosphorylase b kin (374 aa)
initn: 1641 init1: 1432 opt: 1640 Z-score: 630.3 bits: 125.4 E(85289): 2.3e-28
Smith-Waterman score: 1640; 63.7% identity (88.8% similar) in 358 aa overlap (4-361:8-364)
10 20 30 40 50
pF1KE0 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGG
.. ::: .:..::..:.::...:::::::::::.:. :..:.:::...::.
NP_001 MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE0 GSFSPEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYL
.:::...:.:::: .:. :::.:.:::.:: : :.::...:.:::::::..:::::::
NP_001 -RLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYL
70 80 90 100 110
120 130 140 150 160 170
pF1KE0 TEKVTLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLE
::::.:::::::.:::.:::.. :: ::::::::::::::::::.:.:.::::::.::
NP_001 TEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE0 PGERLREVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQM
:::.:::.::::.::::::..:::.: :::::::::.:. :::..::::::::::::.:.
NP_001 PGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQI
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE0 LMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEV
::::::: :.:::.:::::: :.:::::.::.: :.:. : :::.:: ::::.. .
NP_001 LMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE0 RHFSPRGKFKVIALTVLASVRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYG
...:: .:.: . ::::. :. . .::.:.:.. ..::::::: .:.::: :::.::
NP_001 WNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYG
300 310 320 330 340 350
360 370 380
pF1KE0 HWVKKGQQQNRAALFENTPKAVLLSLAEEDY
::..:
NP_001 HWIRKQWIGKLMACV
360 370
>>XP_016867816 (OMIM: 172470) PREDICTED: phosphorylase b (326 aa)
initn: 1877 init1: 1396 opt: 1396 Z-score: 543.3 bits: 109.0 E(85289): 1.6e-23
Smith-Waterman score: 1791; 86.2% identity (86.2% similar) in 326 aa overlap (107-387:1-326)
80 90 100 110 120 130
pF1KE0 ILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLE
::::::::::::::::::::::::::::::
XP_016 MKRGELFDYLTEKVTLSEKETRKIMRALLE
10 20 30
140 150 160 170 180
pF1KE0 VICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLR--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLRVETGFHHVGQAGLE
40 50 60 70 80 90
190 200 210
pF1KE0 -------------------------------EVCGTPSYLAPEIIECSMNEDHPGYGKEV
:::::::::::::::::::::::::::::
XP_016 LLTLRSARLGLPKCCDYRREPPCPAGLGISSEVCGTPSYLAPEIIECSMNEDHPGYGKEV
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE0 DMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVV
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE0 QPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLASVRIYYQYRRVKPVTRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLASVRIYYQYRRVKPVTRE
220 230 240 250 260 270
340 350 360 370 380
pF1KE0 IVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKAVLLSLAEEDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKAVLLSLAEEDY
280 290 300 310 320
>>XP_016867815 (OMIM: 172470) PREDICTED: phosphorylase b (354 aa)
initn: 1878 init1: 1396 opt: 1396 Z-score: 542.9 bits: 109.1 E(85289): 1.7e-23
Smith-Waterman score: 1816; 71.5% identity (71.5% similar) in 432 aa overlap (1-387:1-354)
10 20 30 40 50 60
pF1KE0 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFS
::::::::::::::::::::::::::::
XP_016 MTRDEALPDSHSAQDFYENYEPKEILGR--------------------------------
10 20
70 80 90 100 110 120
pF1KE0 PEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKV
::::::::::::::
XP_016 ----------------------------------------------MKRGELFDYLTEKV
30 40
130 140 150 160 170 180
pF1KE0 TLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER
50 60 70 80 90 100
190
pF1KE0 LR---------------------------------------------EVCGTPSYLAPEI
:: :::::::::::::
XP_016 LRVETGFHHVGQAGLELLTLRSARLGLPKCCDYRREPPCPAGLGISSEVCGTPSYLAPEI
110 120 130 140 150 160
200 210 220 230 240 250
pF1KE0 IECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWD
170 180 190 200 210 220
260 270 280 290 300 310
pF1KE0 DYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLAS
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE0 VRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTP
290 300 310 320 330 340
380
pF1KE0 KAVLLSLAEEDY
::::::::::::
XP_016 KAVLLSLAEEDY
350
>>XP_016867814 (OMIM: 172470) PREDICTED: phosphorylase b (378 aa)
initn: 1877 init1: 1396 opt: 1396 Z-score: 542.6 bits: 109.1 E(85289): 1.7e-23
Smith-Waterman score: 1791; 86.2% identity (86.2% similar) in 326 aa overlap (107-387:53-378)
80 90 100 110 120 130
pF1KE0 ILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMRALLE
::::::::::::::::::::::::::::::
XP_016 LQPGGGAGAARSHAEGGGHPAQGLRAPQHQMKRGELFDYLTEKVTLSEKETRKIMRALLE
30 40 50 60 70 80
140 150 160 170 180
pF1KE0 VICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLR--------------
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLRVETGFHHVGQAGLE
90 100 110 120 130 140
190 200 210
pF1KE0 -------------------------------EVCGTPSYLAPEIIECSMNEDHPGYGKEV
:::::::::::::::::::::::::::::
XP_016 LLTLRSARLGLPKCCDYRREPPCPAGLGISSEVCGTPSYLAPEIIECSMNEDHPGYGKEV
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE0 DMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVV
210 220 230 240 250 260
280 290 300 310 320 330
pF1KE0 QPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLASVRIYYQYRRVKPVTRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLASVRIYYQYRRVKPVTRE
270 280 290 300 310 320
340 350 360 370 380
pF1KE0 IVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKAVLLSLAEEDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTPKAVLLSLAEEDY
330 340 350 360 370
>>XP_016867813 (OMIM: 172470) PREDICTED: phosphorylase b (432 aa)
initn: 2569 init1: 1396 opt: 1396 Z-score: 542.0 bits: 109.2 E(85289): 1.9e-23
Smith-Waterman score: 2397; 89.3% identity (89.3% similar) in 419 aa overlap (14-387:14-432)
10 20 30 40 50 60
pF1KE0 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFS
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTRDEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDVTGGGSFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 PEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEEVRELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 TLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLSEKETRKIMRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGER
130 140 150 160 170 180
190
pF1KE0 LR---------------------------------------------EVCGTPSYLAPEI
:: :::::::::::::
XP_016 LRVETGFHHVGQAGLELLTLRSARLGLPKCCDYRREPPCPAGLGISSEVCGTPSYLAPEI
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE0 IECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IECSMNEDHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWD
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE0 DYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYSDTVKDLVSRFLVVQPQNRYTAEEALAHPFFQQYLVEEVRHFSPRGKFKVIALTVLAS
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE0 VRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRIYYQYRRVKPVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRAALFENTP
370 380 390 400 410 420
380
pF1KE0 KAVLLSLAEEDY
::::::::::::
XP_016 KAVLLSLAEEDY
430
387 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 18:18:01 2016 done: Mon Nov 7 18:18:02 2016
Total Scan time: 7.870 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]