Result of FASTA (omim) for
pFN21AE0973
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE0973, 545 aa
1>>>pF1KE0973 545 - 545 aa - 545 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.1911+/-0.00057; mu= -5.7747+/- 0.035
mean_var=666.2681+/-141.627, 0's: 0 Z-trim(120.0): 1399 B-trim: 33 in 1/57
Lambda= 0.049688
statistics sampled from 32695 (34793) to 32695 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.408), width: 16
Scan time: 9.950
The best scores are: opt bits E(85289)
NP_037365 (OMIM: 607648) STE20/SPS1-related prolin ( 545) 3582 272.4 2.5e-72
XP_016859302 (OMIM: 607648) PREDICTED: STE20/SPS1- ( 535) 3430 261.5 4.6e-69
XP_016859303 (OMIM: 607648) PREDICTED: STE20/SPS1- ( 461) 3032 232.9 1.7e-60
XP_016859304 (OMIM: 607648) PREDICTED: STE20/SPS1- ( 443) 2909 224.1 7.3e-58
XP_005246522 (OMIM: 607648) PREDICTED: STE20/SPS1- ( 524) 2748 212.6 2.4e-54
XP_016859306 (OMIM: 607648) PREDICTED: STE20/SPS1- ( 381) 2452 191.2 4.9e-48
XP_016859305 (OMIM: 607648) PREDICTED: STE20/SPS1- ( 393) 2395 187.1 8.4e-47
NP_005100 (OMIM: 604046) serine/threonine-protein ( 527) 2081 164.8 5.9e-40
XP_011532633 (OMIM: 604046) PREDICTED: serine/thre ( 580) 2004 159.4 2.9e-38
XP_016863090 (OMIM: 604046) PREDICTED: serine/thre ( 568) 1979 157.6 9.8e-38
XP_005265695 (OMIM: 604046) PREDICTED: serine/thre ( 460) 1569 128.0 6.2e-29
XP_016863091 (OMIM: 604046) PREDICTED: serine/thre ( 335) 1002 87.2 8.9e-17
XP_011517813 (OMIM: 606808,607101) PREDICTED: myos (1009) 650 62.7 6.5e-09
XP_011517812 (OMIM: 606808,607101) PREDICTED: myos (1135) 650 62.7 6.9e-09
XP_011517810 (OMIM: 606808,607101) PREDICTED: myos (1435) 650 62.9 7.9e-09
XP_011517808 (OMIM: 606808,607101) PREDICTED: myos (1523) 650 62.9 8.1e-09
XP_011517807 (OMIM: 606808,607101) PREDICTED: myos (1532) 650 62.9 8.1e-09
XP_011517806 (OMIM: 606808,607101) PREDICTED: myos (1565) 650 62.9 8.2e-09
XP_011517805 (OMIM: 606808,607101) PREDICTED: myos (1568) 650 62.9 8.3e-09
XP_011517804 (OMIM: 606808,607101) PREDICTED: myos (1612) 650 63.0 8.4e-09
XP_011517802 (OMIM: 606808,607101) PREDICTED: myos (1616) 650 63.0 8.4e-09
NP_059129 (OMIM: 606808,607101) myosin-IIIa [Homo (1616) 650 63.0 8.4e-09
XP_011517800 (OMIM: 606808,607101) PREDICTED: myos (1616) 650 63.0 8.4e-09
XP_011517801 (OMIM: 606808,607101) PREDICTED: myos (1616) 650 63.0 8.4e-09
NP_001257354 (OMIM: 604921) mitogen-activated prot ( 873) 599 58.9 7.5e-08
NP_003609 (OMIM: 604921) mitogen-activated protein ( 894) 599 58.9 7.6e-08
XP_011538703 (OMIM: 616563) PREDICTED: STE20-like ( 783) 584 57.8 1.5e-07
NP_001291672 (OMIM: 616563) STE20-like serine/thre (1204) 587 58.3 1.6e-07
NP_055535 (OMIM: 616563) STE20-like serine/threoni (1235) 587 58.3 1.7e-07
XP_016873585 (OMIM: 603166) PREDICTED: mitogen-act ( 584) 575 56.9 2e-07
XP_011543505 (OMIM: 603166) PREDICTED: mitogen-act ( 797) 575 57.1 2.4e-07
XP_016860864 (OMIM: 604666) PREDICTED: mitogen-act (1155) 579 57.7 2.4e-07
NP_005981 (OMIM: 603919) serine/threonine-protein ( 968) 577 57.4 2.4e-07
XP_016860863 (OMIM: 604666) PREDICTED: mitogen-act (1158) 579 57.7 2.4e-07
NP_001294919 (OMIM: 603166) mitogen-activated prot ( 812) 575 57.1 2.4e-07
XP_016860862 (OMIM: 604666) PREDICTED: mitogen-act (1163) 579 57.7 2.4e-07
NP_004825 (OMIM: 604666) mitogen-activated protein (1165) 579 57.7 2.4e-07
XP_016860861 (OMIM: 604666) PREDICTED: mitogen-act (1166) 579 57.7 2.4e-07
NP_004570 (OMIM: 603166) mitogen-activated protein ( 820) 575 57.1 2.4e-07
XP_005264128 (OMIM: 604666) PREDICTED: mitogen-act (1185) 579 57.7 2.4e-07
XP_016860860 (OMIM: 604666) PREDICTED: mitogen-act (1186) 579 57.7 2.4e-07
XP_016860859 (OMIM: 604666) PREDICTED: mitogen-act (1188) 579 57.7 2.4e-07
XP_006712932 (OMIM: 604666) PREDICTED: mitogen-act (1189) 579 57.7 2.4e-07
XP_016860858 (OMIM: 604666) PREDICTED: mitogen-act (1196) 579 57.7 2.4e-07
XP_005264126 (OMIM: 604666) PREDICTED: mitogen-act (1209) 579 57.7 2.4e-07
XP_016860857 (OMIM: 604666) PREDICTED: mitogen-act (1211) 579 57.7 2.4e-07
NP_663720 (OMIM: 604666) mitogen-activated protein (1212) 579 57.7 2.4e-07
XP_006712931 (OMIM: 604666) PREDICTED: mitogen-act (1222) 579 57.7 2.4e-07
XP_005264125 (OMIM: 604666) PREDICTED: mitogen-act (1227) 579 57.7 2.5e-07
XP_005264123 (OMIM: 604666) PREDICTED: mitogen-act (1229) 579 57.7 2.5e-07
>>NP_037365 (OMIM: 607648) STE20/SPS1-related proline-al (545 aa)
initn: 3582 init1: 3582 opt: 3582 Z-score: 1419.6 bits: 272.4 E(85289): 2.5e-72
Smith-Waterman score: 3582; 100.0% identity (100.0% similar) in 545 aa overlap (1-545:1-545)
10 20 30 40 50 60
pF1KE0 MAEPSGSPVHVQLPQQAAPVTAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MAEPSGSPVHVQLPQQAAPVTAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 PEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 EMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 EMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 AKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 AKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSAS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 TIPEQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 TIPEQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTAD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 GVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 GVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFA
490 500 510 520 530 540
pF1KE0 QLSVS
:::::
NP_037 QLSVS
>>XP_016859302 (OMIM: 607648) PREDICTED: STE20/SPS1-rela (535 aa)
initn: 3808 init1: 3430 opt: 3430 Z-score: 1360.8 bits: 261.5 E(85289): 4.6e-69
Smith-Waterman score: 3430; 99.1% identity (99.4% similar) in 527 aa overlap (1-527:1-527)
10 20 30 40 50 60
pF1KE0 MAEPSGSPVHVQLPQQAAPVTAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAEPSGSPVHVQLPQQAAPVTAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 EMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 AKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSAS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 TIPEQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIPEQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTAD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE0 GVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFA
::::::::::::::::::::::::::::::::::::::::: .. :
XP_016 GVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLRNSNPGPFLLPKIL
490 500 510 520 530
pF1KE0 QLSVS
>>XP_016859303 (OMIM: 607648) PREDICTED: STE20/SPS1-rela (461 aa)
initn: 3032 init1: 3032 opt: 3032 Z-score: 1207.3 bits: 232.9 E(85289): 1.7e-60
Smith-Waterman score: 3032; 100.0% identity (100.0% similar) in 459 aa overlap (1-459:1-459)
10 20 30 40 50 60
pF1KE0 MAEPSGSPVHVQLPQQAAPVTAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAEPSGSPVHVQLPQQAAPVTAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 EMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 AKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSAS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE0 TIPEQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTAD
:::::::::::::::::::::::::::::::::::::::
XP_016 TIPEQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLRWT
430 440 450 460
490 500 510 520 530 540
pF1KE0 GVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFA
>>XP_016859304 (OMIM: 607648) PREDICTED: STE20/SPS1-rela (443 aa)
initn: 2909 init1: 2909 opt: 2909 Z-score: 1159.8 bits: 224.1 E(85289): 7.3e-58
Smith-Waterman score: 2909; 100.0% identity (100.0% similar) in 443 aa overlap (103-545:1-443)
80 90 100 110 120 130
pF1KE0 ATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKD
::::::::::::::::::::::::::::::
XP_016 MDELLKEIQAMSQCSHPNVVTYYTSFVVKD
10 20 30
140 150 160 170 180 190
pF1KE0 ELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRD
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE0 LKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDF
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE0 KADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRK
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE0 LLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRRVPGSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRRVPGSSG
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE0 HLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSASTIPEQIQSLSVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSASTIPEQIQSLSVH
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE0 DSQGPPNANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSQGPPNANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLV
340 350 360 370 380 390
500 510 520 530 540
pF1KE0 DGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSVS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSVS
400 410 420 430 440
>>XP_005246522 (OMIM: 607648) PREDICTED: STE20/SPS1-rela (524 aa)
initn: 2748 init1: 2748 opt: 2748 Z-score: 1096.7 bits: 212.6 E(85289): 2.4e-54
Smith-Waterman score: 3405; 96.1% identity (96.1% similar) in 545 aa overlap (1-545:1-524)
10 20 30 40 50 60
pF1KE0 MAEPSGSPVHVQLPQQAAPVTAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAEPSGSPVHVQLPQQAAPVTAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 EMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 AKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPE------
370 380 390 400 410
430 440 450 460 470 480
pF1KE0 TIPEQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTAD
:::::::::::::::::::::::::::::::::::::::::::::
XP_005 ---------------GPPNANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTAD
420 430 440 450
490 500 510 520 530 540
pF1KE0 GVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFA
460 470 480 490 500 510
pF1KE0 QLSVS
:::::
XP_005 QLSVS
520
>>XP_016859306 (OMIM: 607648) PREDICTED: STE20/SPS1-rela (381 aa)
initn: 2452 init1: 2452 opt: 2452 Z-score: 983.4 bits: 191.2 E(85289): 4.9e-48
Smith-Waterman score: 2452; 99.2% identity (99.5% similar) in 375 aa overlap (171-545:7-381)
150 160 170 180 190 200
pF1KE0 LSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILL
. ::::::::: ::::::::::::::::::
XP_016 MFKFRCSYLKEVLEGLDCLHRNGQIHRDLKAGNILL
10 20 30
210 220 230 240 250 260
pF1KE0 GEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFG
40 50 60 70 80 90
270 280 290 300 310 320
pF1KE0 ITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQK
100 110 120 130 140 150
330 340 350 360 370 380
pF1KE0 DPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRRVPGSSGHLHKTEDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRRVPGSSGHLHKTEDG
160 170 180 190 200 210
390 400 410 420 430 440
pF1KE0 DWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSASTIPEQIQSLSVHDSQGPPNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSASTIPEQIQSLSVHDSQGPPNA
220 230 240 250 260 270
450 460 470 480 490 500
pF1KE0 NEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIV
280 290 300 310 320 330
510 520 530 540
pF1KE0 AANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSVS
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 AANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSVS
340 350 360 370 380
>>XP_016859305 (OMIM: 607648) PREDICTED: STE20/SPS1-rela (393 aa)
initn: 2727 init1: 2395 opt: 2395 Z-score: 961.2 bits: 187.1 E(85289): 8.4e-47
Smith-Waterman score: 2395; 99.7% identity (99.7% similar) in 365 aa overlap (1-365:1-365)
10 20 30 40 50 60
pF1KE0 MAEPSGSPVHVQLPQQAAPVTAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAEPSGSPVHVQLPQQAAPVTAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE0 DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE0 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE0 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE0 PEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE0 EMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE0 AKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSAS
::: :
XP_016 AKKHRNKEKILKSAREVKQITYQVIITRLTAGI
370 380 390
>>NP_005100 (OMIM: 604046) serine/threonine-protein kina (527 aa)
initn: 2537 init1: 2076 opt: 2081 Z-score: 838.3 bits: 164.8 E(85289): 5.9e-40
Smith-Waterman score: 2520; 74.6% identity (88.2% similar) in 524 aa overlap (51-545:5-527)
30 40 50 60 70 80
pF1KE0 TAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICRDAYELQEVIGSGATAVVQAA
..:. : : :: ::::::::::::::::::
NP_005 MSEDSSALPWSINRDDYELQEVIGSGATAVVQAA
10 20 30
90 100 110 120 130 140
pF1KE0 LCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKL
: :..:.:::::::::::::::::::::::::::: :::.:.:::::::::::::::::
NP_005 YCAPKKEKVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE0 LSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILL
:::::.:::::.:: .::::.:::.:. :::::.::::::.:::.:::::::.:::::::
NP_005 LSGGSVLDIIKHIVAKGEHKSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILL
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE0 GEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFG
::::::::::::::::::::::.::::::::::::::::::::::::::::::::.::::
NP_005 GEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFG
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE0 ITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQK
:::::::::::::::::::::::::::::::.:::::.::::.:::::::::..::::::
NP_005 ITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQK
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE0 DPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRRVPGSSGHLHKTEDG
:: :::::::::. ::::::::.:.: :: : :.: :..:::::::::::::.:::::::
NP_005 DPEKRPTAAELLRHKFFQKAKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDG
280 290 300 310 320 330
390 400 410 420
pF1KE0 DWEWSDDEMDEKSEEGKAAFSQEKSRRVKEE--NPEIAVSASTI------PEQIQS----
:::::::.::.:::::::.:: .: :::: : :. ... . ::::..
NP_005 GWEWSDDEFDEESEEGKAAISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLPQ
340 350 360 370 380 390
430 440 450 460 470
pF1KE0 ----LSVHDSQG--PPNANEDYREASSCA-----------VNLVLRLRNSRKELNDIRFE
.... .: ::.: : . :.. . ..::::::::.:::::::::
NP_005 PAGQIATQPTQVSLPPTA-EPAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFE
400 410 420 430 440 450
480 490 500 510 520 530
pF1KE0 FTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIP
::::::::.::::::.:::::::.:.:::::::::::..:.. ...::::::: .::.::
NP_005 FTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIP
460 470 480 490 500 510
540
pF1KE0 DEVKLIGFAQLSVS
:. :::::::::.:
NP_005 DDGKLIGFAQLSIS
520
>>XP_011532633 (OMIM: 604046) PREDICTED: serine/threonin (580 aa)
initn: 2460 init1: 1999 opt: 2004 Z-score: 808.0 bits: 159.4 E(85289): 2.9e-38
Smith-Waterman score: 2443; 75.0% identity (88.5% similar) in 505 aa overlap (70-545:77-580)
40 50 60 70 80 90
pF1KE0 PAAPAPAPAPAAQAVGWPICRDAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKC
::::::::::: : :..:.:::::::::::
XP_011 YIQPHWRWRPEAGPRWGVTSAVTSARCVSAGSGATAVVQAAYCAPKKEKVAIKRINLEKC
50 60 70 80 90 100
100 110 120 130 140 150
pF1KE0 QTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEH
::::::::::::::::: :::.:.::::::::::::::::::::::.:::::.:: .:::
XP_011 QTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEH
110 120 130 140 150 160
160 170 180 190 200 210
pF1KE0 KNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLAT
:.:::.:. :::::.::::::.:::.:::::::.::::::::::::::::::::::::::
XP_011 KSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLAT
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE0 GGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPM
:::.::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_011 GGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPM
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE0 KVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQK
::::::::::::.:::::.::::.:::::::::..:::::::: :::::::::. :::::
XP_011 KVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQK
290 300 310 320 330 340
340 350 360 370 380 390
pF1KE0 AKNREYLIEKLLTRTPDIAQRAKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAA
:::.:.: :: : :.: :..:::::::::::::.::::::: :::::::.::.:::::::
XP_011 AKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEESEEGKAA
350 360 370 380 390 400
400 410 420 430 440
pF1KE0 FSQEKSRRVKEE--NPEIAVSASTI------PEQIQS--------LSVHDSQG--PPNAN
.:: .: :::: : :. ... . ::::.. .... .: ::.:
XP_011 ISQLRSPRVKESISNSELFPTTDPVGTLLQVPEQISAHLPQPAGQIATQPTQVSLPPTA-
410 420 430 440 450 460
450 460 470 480 490
pF1KE0 EDYREASSCA-----------VNLVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAG
: . :.. . ..::::::::.:::::::::::::::::.::::::.:::
XP_011 EPAKTAQALSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAG
470 480 490 500 510 520
500 510 520 530 540
pF1KE0 LVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSVS
::::.:.:::::::::::..:.. ...::::::: .::.:::. :::::::::.:
XP_011 LVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSIS
530 540 550 560 570 580
>>XP_016863090 (OMIM: 604046) PREDICTED: serine/threonin (568 aa)
initn: 2434 init1: 1973 opt: 1979 Z-score: 798.4 bits: 157.6 E(85289): 9.8e-38
Smith-Waterman score: 2421; 75.4% identity (89.1% similar) in 495 aa overlap (70-545:77-568)
40 50 60 70 80 90
pF1KE0 PAAPAPAPAPAAQAVGWPICRDAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKC
::::::::::: : :..:.:::::::::::
XP_016 YIQPHWRWRPEAGPRWGVTSAVTSARCVSAGSGATAVVQAAYCAPKKEKVAIKRINLEKC
50 60 70 80 90 100
100 110 120 130 140 150
pF1KE0 QTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEH
::::::::::::::::: :::.:.::::::::::::::::::::::.:::::.:: .:::
XP_016 QTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEH
110 120 130 140 150 160
160 170 180 190 200 210
pF1KE0 KNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLAT
:.:::.:. :::::.::::::.:::.:::::::.::::::::::::::::::::::::::
XP_016 KSGVLDESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLAT
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE0 GGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPM
:::.::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
XP_016 GGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPM
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE0 KVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQK
::::::::::::.:::::.::::.:::::::::..:::::::: :::::::::. :::::
XP_016 KVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQK
290 300 310 320 330 340
340 350 360 370 380 390
pF1KE0 AKNREYLIEKLLTRTPDIAQRAKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAA
:::.:.: :: : :.: :..:::::::::::::.::::::: :::::::.::.:::::::
XP_016 AKNKEFLQEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEESEEGKAA
350 360 370 380 390 400
400 410 420 430 440 450
pF1KE0 FSQEKSRRVKE------ENPEIAVSASTIPEQIQSLSVHDSQG--PPNANEDYREASSCA
.:: . . . . :: .:: .:. ..... .: ::.: : . :.. .
XP_016 ISQLRLFPTTDPVGTLLQVPE-QISAH-LPQPAGQIATQPTQVSLPPTA-EPAKTAQALS
410 420 430 440 450 460
460 470 480 490 500
pF1KE0 -----------VNLVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIV
..::::::::.:::::::::::::::::.::::::.:::::::.:.:::
XP_016 SGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIV
470 480 490 500 510 520
510 520 530 540
pF1KE0 AANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSVS
::::::::..:.. ...::::::: .::.:::. :::::::::.:
XP_016 AANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSIS
530 540 550 560
545 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:13:03 2016 done: Mon Nov 7 16:13:04 2016
Total Scan time: 9.950 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]