Result of FASTA (ccds) for
pFN21AE1945
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1945, 500 aa
1>>>pF1KE1945 500 - 500 aa - 500 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1886+/-0.000817; mu= 18.6656+/- 0.049
mean_var=66.9838+/-14.090, 0's: 0 Z-trim(106.8): 48 B-trim: 600 in 2/52
Lambda= 0.156707
statistics sampled from 9136 (9183) to 9136 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.282), width: 16
Scan time: 2.930
The best scores are: opt bits E(32554)
CCDS13419.1 PTGIS gene_id:5740|Hs108|chr20 ( 500) 3345 765.3 0
CCDS2707.1 CYP8B1 gene_id:1582|Hs108|chr3 ( 501) 1303 303.7 3.2e-82
CCDS6171.1 CYP7A1 gene_id:1581|Hs108|chr8 ( 504) 923 217.8 2.3e-56
CCDS6180.1 CYP7B1 gene_id:9420|Hs108|chr8 ( 506) 829 196.5 5.8e-50
>>CCDS13419.1 PTGIS gene_id:5740|Hs108|chr20 (500 aa)
initn: 3345 init1: 3345 opt: 3345 Z-score: 4084.7 bits: 765.3 E(32554): 0
Smith-Waterman score: 3345; 100.0% identity (100.0% similar) in 500 aa overlap (1-500:1-500)
10 20 30 40 50 60
pF1KE1 MAWAALLGLLAALLLLLLLSRRRTRRPGEPPLDLGSIPWLGYALDFGKDAASFLTRMKEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MAWAALLGLLAALLLLLLLSRRRTRRPGEPPLDLGSIPWLGYALDFGKDAASFLTRMKEK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 HGDIFTILVGGRYVTVLLDPHSYDAVVWEPRTRLDFHAYAIFLMERIFDVQLPHYSPSDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 HGDIFTILVGGRYVTVLLDPHSYDAVVWEPRTRLDFHAYAIFLMERIFDVQLPHYSPSDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 KARMKLTLLHRELQALTEAMYTNLHAVLLGDATEAGSGWHEMGLLDFSYSFLLRAGYLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 KARMKLTLLHRELQALTEAMYTNLHAVLLGDATEAGSGWHEMGLLDFSYSFLLRAGYLTL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 YGIEALPRTHESQAQDRVHSADVFHTFRQLDRLLPKLARGSLSVGDKDHMCSVKSRLWKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 YGIEALPRTHESQAQDRVHSADVFHTFRQLDRLLPKLARGSLSVGDKDHMCSVKSRLWKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 LSPARLARRAHRSKWLESYLLHLEEMGVSEEMQARALVLQLWATQGNMGPAAFWLLLFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LSPARLARRAHRSKWLESYLLHLEEMGVSEEMQARALVLQLWATQGNMGPAAFWLLLFLL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 KNPEALAAVRGELESILWQAEQPVSQTTTLPQKVLDSTPVLDSVLSESLRLTAAPFITRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 KNPEALAAVRGELESILWQAEQPVSQTTTLPQKVLDSTPVLDSVLSESLRLTAAPFITRE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 VVVDLAMPMADGREFNLRRGDRLLLFPFLSPQRDPEIYTDPEVFKYNRFLNPDGSEKKDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 VVVDLAMPMADGREFNLRRGDRLLLFPFLSPQRDPEIYTDPEVFKYNRFLNPDGSEKKDF
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE1 YKDGKRLKNYNMPWGAGHNHCLGRSYAVNSIKQFVFLVLVHLDLELINADVEIPEFDLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 YKDGKRLKNYNMPWGAGHNHCLGRSYAVNSIKQFVFLVLVHLDLELINADVEIPEFDLSR
430 440 450 460 470 480
490 500
pF1KE1 YGFGLMQPEHDVPVRYRIRP
::::::::::::::::::::
CCDS13 YGFGLMQPEHDVPVRYRIRP
490 500
>>CCDS2707.1 CYP8B1 gene_id:1582|Hs108|chr3 (501 aa)
initn: 1292 init1: 907 opt: 1303 Z-score: 1589.7 bits: 303.7 E(32554): 3.2e-82
Smith-Waterman score: 1303; 40.9% identity (69.4% similar) in 506 aa overlap (3-500:4-499)
10 20 30 40 50
pF1KE1 MAWAALLGLLAALL--LLLLLSRRRTRRPGEPPLDLGSIPWLGYALDFGKDAASFLTRM
:. .:: : ... : : . : ::: ::::: :..::::.:. : :. :: ::
CCDS27 MVLWGPVLGALLVVIAGYLCLPGMLRQRRPWEPPLDKGTVPWLGHAMAFRKNMFEFLKRM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 KEKHGDIFTILVGGRYVTVLLDPHSYDAVVWEPRTRLDFHAYAIFLMERIF---DVQLPH
. ::::.::. .::.: : ..:: :. ... . . .::: :: :. ..: .:: :
CCDS27 RTKHGDVFTVQLGGQYFTFVMDPLSFGSILKDTQRKLDFGQYAKKLVLKVFGYRSVQGDH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 YSPSDEKARMKLTLLHRELQALTEAMYTNLHAVLL---GDATEAGSGWHEMGLLDFSYSF
. ... : :. :.:.: .: :.: : . .: : ::: .:. : : .
CCDS27 EMIHSASTKH---LRGDGLKDLNETMLDSLSFVMLTSKGWSLDA-SCWHEDSLFRFCYYI
130 140 150 160 170
180 190 200 210 220 230
pF1KE1 LLRAGYLTLYGIEALPRTHESQAQDRVHSADVFHTFRQLDRLLPKLARGSLSVGDKDHMC
:. ::::.:.: ... :: ......: ::..: :.:... . : . ..
CCDS27 LFTAGYLSLFGYT------KDKEQDLLQAGELFMEFRKFDLLFPRFVYSLLWPREWLEVG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE1 SVKSRLWKLLSPARLARRAHRSKWLESYLLHLEEMGVSEEMQARALVLQLWATQGNMGPA
.. . :.:: .. .. :.:: ..: :.:.:: :: . ..:::.::: ::.
CCDS27 RLQRLFHKMLSVSHSQEKEGISNWLGNMLQFLREQGVPSAMQDKFNFMMLWASQGNTGPT
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE1 AFWLLLFLLKNPEALAAVRGELESILWQAEQPVSQTTTLPQKVLDSTPVLDSVLSESLRL
.:: ::.:::.:::. ::: : ..: .:. ..:. .. .:. :::::::. :.:::
CCDS27 SFWALLYLLKHPEAIRAVREEATQVLGEARLETKQSFAFKLGALQHTPVLDSVVEETLRL
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE1 TAAPFITREVVVDLAMPMADGREFNLRRGDRLLLFPFLSPQRDPEIYTDPEVFKYNRFLN
::: . : : : .. :..:.:. .:.:: : :::.:: . ::.:. .: ::::.::::
CCDS27 RAAPTLLRLVHEDYTLKMSSGQEYLFRHGDILALFPYLSVHMDPDIHPEPTVFKYDRFLN
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE1 PDGSEKKDFYKDGKRLKNYNMPWGAGHNHCLGRSYAVNSIKQFVFLVLVHLDLELINADV
:.::.: ::.: ::....:.::::.: . : :: .:.. .: :..:...:.::::.. :.
CCDS27 PNGSRKVDFFKTGKKIHHYTMPWGSGVSICPGRFFALSEVKLFILLMVTHFDLELVDPDT
420 430 440 450 460 470
480 490 500
pF1KE1 EIPEFDLSRYGFGLMQPEHDVPVRYRIRP
.:. : .:.::: ::: ::: :::..:
CCDS27 PLPHVDPQRWGFGTMQPSHDVRFRYRLHPTE
480 490 500
>>CCDS6171.1 CYP7A1 gene_id:1581|Hs108|chr8 (504 aa)
initn: 675 init1: 349 opt: 923 Z-score: 1125.4 bits: 217.8 E(32554): 2.3e-56
Smith-Waterman score: 923; 33.0% identity (64.2% similar) in 509 aa overlap (1-499:6-502)
10 20 30 40 50
pF1KE1 MAWAALLGLLAALLLLLLLSRRRTRRPGEPPLDLGSIPWLGYALDFGKDAASFLT
. :. .. : :.: . ::.: :::::. : ::.:: ::.:: . ::
CCDS61 MMTTSLIWGIAIAACCCLWLILGIRRRQT---GEPPLENGLIPYLGCALQFGANPLEFLR
10 20 30 40 50
60 70 80 90 100 110
pF1KE1 RMKEKHGDIFTILVGGRYVTVLLDPHSYDAVVWEPR----TRLDFHAYAIFLMERIFDVQ
..::: .:: . :.:: . .: :: :. . . .. : . : . .: .: .
CCDS61 ANQRKHGHVFTCKLMGKYVHFITNPLSYHKVLCHGKYFDWKKFHFATSAKAFGHRSIDPM
60 70 80 90 100 110
120 130 140 150 160
pF1KE1 LPHYSPSDEKARMKLTLLHRELQALTEAMYTNLHAVLLGDATEAG--SGWHEMGLLDFSY
. . . . . .: :: . :..:::.:. ::. .. .. . ..: :. .: :
CCDS61 DGNTTENINDTFIK-TLQGHALNSLTESMMENLQRIMRPPVSSNSKTAAWVTEGMYSFCY
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 SFLLRAGYLTLYGIEALPRTHESQAQDRVHSADVFHTFRQLDRLLPKLARGSLSVGDKDH
...:::::..: . : : ...: ..: . . .:.:.:...: :. : : .
CCDS61 RVMFEAGYLTIFGRD-LTR-RDTQ---KAHILNNLDNFKQFDKVFPALVAG-LPIHMFRT
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 MCSVKSRLWKLLSPARLARRAHRSKWLESYLLHLEEMGVSEEMQ-ARALVLQLWATQGNM
... .: . : : .: :. . .. . ... .... :.. .. :::.:.:
CCDS61 AHNAREKLAESLRHENLQKRESISELISLRMFLNDTLSTFDDLEKAKTHLVVLWASQANT
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE1 GPAAFWLLLFLLKNPEALAAVRGELESILWQAEQPVS---QTTTLPQKVLDSTPVLDSVL
::.:: :. ...::::. :. :.. : .: : :: . : : :.. :::::..
CCDS61 IPATFWSLFQMIRNPEAMKAATEEVKRTLENAGQKVSLEGNPICLSQAELNDLPVLDSII
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE1 SESLRLTAAPFITREVVVDLAMPMADGREFNLRRGDRLLLFPFLSPQRDPEIYTDPEVFK
.:::::..: . : . :... . :: .:.:. : . :.: : . ::::: :: .::
CCDS61 KESLRLSSASLNIRTAKEDFTLHLEDGS-YNIRKDDIIALYPQLM-HLDPEIYPDPLTFK
360 370 380 390 400
410 420 430 440 450 460
pF1KE1 YNRFLNPDGSEKKDFYKDGKRLKNYNMPWGAGHNHCLGRSYAVNSIKQFVFLVLVHLDLE
:.:.:. .:. : :: .: .:: : ::.:.: . : :: .:.. ::::..:.: ...::
CCDS61 YDRYLDENGKTKTTFYCNGLKLKYYYMPFGSGATICPGRLFAIHEIKQFLILMLSYFELE
410 420 430 440 450 460
470 480 490 500
pF1KE1 LINADVEIPEFDLSRYGFGLMQPEHDVPVRYRIRP
::..... : .: :: :.:.. : .:. .:...
CCDS61 LIEGQAKCPPLDQSRAGLGILPPLNDIEFKYKFKHL
470 480 490 500
>>CCDS6180.1 CYP7B1 gene_id:9420|Hs108|chr8 (506 aa)
initn: 695 init1: 277 opt: 829 Z-score: 1010.5 bits: 196.5 E(32554): 5.8e-50
Smith-Waterman score: 882; 34.1% identity (63.9% similar) in 499 aa overlap (7-499:22-505)
10 20 30 40
pF1KE1 MAWAALLGLLAALLLLLL-LSRRRTRRPGEPPLDLGSIPWLGYAL
:.: :::::: : : ::::::::::: : .:.:: .:
CCDS61 MAGEVSAATGRFSLERLGLPGLALAAALLLLALCLLVRRTRRPGEPPLIKGWLPYLGVVL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 DFGKDAASFLTRMKEKHGDIFTILVGGRYVTVLLDPHSYDAVVWEPRTRLDFHAYAIFLM
.. :: :. ....::: ::.:.::.:.: .::: .:. :. . . .:.:.... :.
CCDS61 NLRKDPLRFMKTLQKQHGDTFTVLLGGKYITFILDPFQYQLVI-KNHKQLSFRVFSNKLL
70 80 90 100 110
110 120 130 140 150 160
pF1KE1 ERIFDV-QLPHYSPSDEKARMKLTLLH-RELQALTEAMYTNLHAVLLGDATEAGSGWHEM
:. :.. :: . ... .. .:. . :. : :.:. ::. :. . .. : :
CCDS61 EKAFSISQLQKNHDMNDELHLCYQFLQGKSLDILLESMMQNLKQVFEPQLLKTTS-WDTA
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE1 GLLDFSYSFLLRAGYLTLYGIEALPRTHESQAQDRVHSADVFHTFRQLDRLLPKLARGSL
: : :.... . :.:: . ... .. : : ..: . :. ...
CCDS61 ELYPFCSSIIFEITFTTIYGKVIVCDNNKFISELR-------DDFLKFDDKFAYLV-SNI
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE1 SVGDKDHMCSVKSRLWKLLSPARLARRAHRSKWLESYLLHLEEMGVSEEMQARALVLQ-L
. .. :.. .. : .: .::. :. ..: ::.. : :... : : :
CCDS61 PIELLGNVKSIREKIIKCFSSEKLAKMQGWSEVFQSRQDVLEKYYVHEDLEIGAHHLGFL
240 250 260 270 280 290
290 300 310 320 330
pF1KE1 WATQGNMGPAAFWLLLFLLKNPEALAAVRGELESILWQAEQPVSQ--TTTLPQKVLDSTP
::. .: :. :: . .::..:::.:::: :.. .: .. : .. : .. :::
CCDS61 WASVANTIPTMFWAMYYLLRHPEAMAAVRDEIDRLLQSTGQKKGSGFPIHLTREQLDSLI
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE1 VLDSVLSESLRLTAAPFITREVVVDLAMPMADGREFNLRRGDRLLLFPFLSPQRDPEIYT
:.: . :.:::.. : : ::.. : .. .:.:: . .:: . . ::::.
CCDS61 CLESSIFEALRLSSYSTTIRFVEEDLTLSSETG-DYCVRKGDLVAIFPPVL-HGDPEIFE
360 370 380 390 400
400 410 420 430 440 450
pF1KE1 DPEVFKYNRFLNPDGSEKKDFYKDGKRLKNYNMPWGAGHNHCLGRSYAVNSIKQFVFLVL
:: :.:.::.. ::..: :.: ::.:: : ::.:.: ..: :: .:. :::.. ..:
CCDS61 APEEFRYDRFIE-DGKKKTTFFKRGKKLKCYLMPFGTGTSKCPGRFFALMEIKQLLVILL
410 420 430 440 450 460
460 470 480 490 500
pF1KE1 VHLDLELINADVEIPEFDLSRYGFGLMQPEHDVPVRYRIRP
...:::.:. : : .. :: ::.. :. :: ::...
CCDS61 TYFDLEIID-DKPIG-LNYSRLLFGIQYPDSDVLFRYKVKS
470 480 490 500
500 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 15:50:04 2016 done: Mon Nov 7 15:50:05 2016
Total Scan time: 2.930 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]