Result of FASTA (omim) for
pFN21AE3502
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3502, 1582 aa
1>>>pF1KE3502 1582 - 1582 aa - 1582 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.2714+/-0.000718; mu= -4.9450+/- 0.044
mean_var=963.1578+/-217.125, 0's: 0 Z-trim(116.9): 594 B-trim: 1656 in 1/54
Lambda= 0.041326
statistics sampled from 27720 (28459) to 27720 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.653), E-opt: 0.2 (0.334), width: 16
Scan time: 13.610
The best scores are: opt bits E(85289)
NP_940867 (OMIM: 300791) nik-related protein kinas (1582) 10597 650.4 3.5e-185
XP_006724695 (OMIM: 300791) PREDICTED: nik-related (1574) 10518 645.7 9.2e-184
XP_011529189 (OMIM: 300791) PREDICTED: nik-related (1527) 10220 627.9 2e-178
XP_006724697 (OMIM: 300791) PREDICTED: nik-related (1526) 9112 561.8 1.5e-158
XP_006724696 (OMIM: 300791) PREDICTED: nik-related (1534) 9112 561.8 1.6e-158
XP_016880194 (OMIM: 609426) PREDICTED: misshapen-l (1341) 1309 96.5 1.6e-18
XP_005264125 (OMIM: 604666) PREDICTED: mitogen-act (1227) 1301 96.0 2.1e-18
XP_005264126 (OMIM: 604666) PREDICTED: mitogen-act (1209) 1295 95.6 2.7e-18
XP_005264123 (OMIM: 604666) PREDICTED: mitogen-act (1229) 1293 95.5 3e-18
XP_005264121 (OMIM: 604666) PREDICTED: mitogen-act (1258) 1293 95.5 3e-18
NP_663720 (OMIM: 604666) mitogen-activated protein (1212) 1289 95.2 3.5e-18
XP_016860853 (OMIM: 604666) PREDICTED: mitogen-act (1249) 1289 95.3 3.6e-18
XP_005264120 (OMIM: 604666) PREDICTED: mitogen-act (1260) 1289 95.3 3.6e-18
XP_006712931 (OMIM: 604666) PREDICTED: mitogen-act (1222) 1288 95.2 3.7e-18
XP_005264122 (OMIM: 604666) PREDICTED: mitogen-act (1230) 1288 95.2 3.7e-18
XP_016860842 (OMIM: 604666) PREDICTED: mitogen-act (1306) 1286 95.1 4.1e-18
XP_016860852 (OMIM: 604666) PREDICTED: mitogen-act (1253) 1285 95.0 4.2e-18
XP_005264119 (OMIM: 604666) PREDICTED: mitogen-act (1261) 1285 95.0 4.2e-18
NP_663719 (OMIM: 604666) mitogen-activated protein (1273) 1285 95.0 4.2e-18
XP_016860846 (OMIM: 604666) PREDICTED: mitogen-act (1276) 1285 95.0 4.2e-18
XP_016860845 (OMIM: 604666) PREDICTED: mitogen-act (1281) 1285 95.0 4.2e-18
XP_005264116 (OMIM: 604666) PREDICTED: mitogen-act (1284) 1285 95.0 4.2e-18
XP_016860860 (OMIM: 604666) PREDICTED: mitogen-act (1186) 1283 94.9 4.4e-18
XP_016860840 (OMIM: 604666) PREDICTED: mitogen-act (1311) 1283 94.9 4.7e-18
XP_005264128 (OMIM: 604666) PREDICTED: mitogen-act (1185) 1281 94.7 4.8e-18
XP_016860857 (OMIM: 604666) PREDICTED: mitogen-act (1211) 1280 94.7 5.1e-18
XP_016880195 (OMIM: 609426) PREDICTED: misshapen-l (1323) 1281 94.8 5.1e-18
XP_006721599 (OMIM: 609426) PREDICTED: misshapen-l (1324) 1281 94.8 5.1e-18
XP_006721595 (OMIM: 609426) PREDICTED: misshapen-l (1360) 1281 94.8 5.2e-18
XP_006721594 (OMIM: 609426) PREDICTED: misshapen-l (1361) 1281 94.8 5.2e-18
XP_016860859 (OMIM: 604666) PREDICTED: mitogen-act (1188) 1279 94.6 5.2e-18
XP_016860858 (OMIM: 604666) PREDICTED: mitogen-act (1196) 1279 94.6 5.3e-18
NP_001229488 (OMIM: 604666) mitogen-activated prot (1239) 1279 94.7 5.3e-18
XP_005264115 (OMIM: 604666) PREDICTED: mitogen-act (1312) 1279 94.7 5.5e-18
XP_016860856 (OMIM: 604666) PREDICTED: mitogen-act (1234) 1278 94.6 5.6e-18
XP_016860843 (OMIM: 604666) PREDICTED: mitogen-act (1299) 1278 94.6 5.7e-18
XP_006712928 (OMIM: 604666) PREDICTED: mitogen-act (1307) 1278 94.6 5.7e-18
XP_016860847 (OMIM: 604666) PREDICTED: mitogen-act (1275) 1277 94.6 5.9e-18
XP_005264117 (OMIM: 604666) PREDICTED: mitogen-act (1280) 1277 94.6 5.9e-18
XP_006712932 (OMIM: 604666) PREDICTED: mitogen-act (1189) 1276 94.5 5.9e-18
XP_016860838 (OMIM: 604666) PREDICTED: mitogen-act (1352) 1277 94.6 6.1e-18
NP_001229489 (OMIM: 604666) mitogen-activated prot (1235) 1274 94.4 6.6e-18
XP_016860855 (OMIM: 604666) PREDICTED: mitogen-act (1243) 1274 94.4 6.6e-18
XP_016880193 (OMIM: 609426) PREDICTED: misshapen-l (1358) 1275 94.5 6.6e-18
NP_004825 (OMIM: 604666) mitogen-activated protein (1165) 1269 94.0 7.8e-18
XP_016860854 (OMIM: 604666) PREDICTED: mitogen-act (1243) 1268 94.0 8.4e-18
XP_016860864 (OMIM: 604666) PREDICTED: mitogen-act (1155) 1267 93.9 8.5e-18
XP_016860862 (OMIM: 604666) PREDICTED: mitogen-act (1163) 1267 93.9 8.5e-18
XP_016860851 (OMIM: 604666) PREDICTED: mitogen-act (1265) 1268 94.0 8.5e-18
XP_016860850 (OMIM: 604666) PREDICTED: mitogen-act (1266) 1268 94.0 8.5e-18
>>NP_940867 (OMIM: 300791) nik-related protein kinase [H (1582 aa)
initn: 10597 init1: 10597 opt: 10597 Z-score: 3445.6 bits: 650.4 E(85289): 3.5e-185
Smith-Waterman score: 10597; 100.0% identity (100.0% similar) in 1582 aa overlap (1-1582:1-1582)
10 20 30 40 50 60
pF1KE3 MAGPGGWRDREVTDLGHLPDPTGIFSLDKTIGLGTYGRIYLGLHEKTGAFTAVKVMNARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 MAGPGGWRDREVTDLGHLPDPTGIFSLDKTIGLGTYGRIYLGLHEKTGAFTAVKVMNARK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 TPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QRHQLWMVMELCAAGSVTDVVRMTSNQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 QRHQLWMVMELCAAGSVTDVVRMTSNQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 QNVLLTHNAEVKLVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 QNVLLTHNAEVKLVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 WSVGITAIEMAEGAPPLCNLQPLEALFVILRESAPTVKSSGWSRKFHNFMEKCTIKNFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 WSVGITAIEMAEGAPPLCNLQPLEALFVILRESAPTVKSSGWSRKFHNFMEKCTIKNFLF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 RPTSANMLQHPFVRDIKNERHVVESLTRHLTGIIKKRQKKGIPLIFEREEAIKEQYTVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 RPTSANMLQHPFVRDIKNERHVVESLTRHLTGIIKKRQKKGIPLIFEREEAIKEQYTVRR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FRGPSCTHELLRLPTSSRCRPLRVLHGEPSQPRWLPDREEPQVQALQQLQGAARVFMPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 FRGPSCTHELLRLPTSSRCRPLRVLHGEPSQPRWLPDREEPQVQALQQLQGAARVFMPLQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 ALDSAPKPLKGQAQAPQRLQGAARVFMPLQAQVKAKASKPLQMQIKAPPRLRRAARVLMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 ALDSAPKPLKGQAQAPQRLQGAARVFMPLQAQVKAKASKPLQMQIKAPPRLRRAARVLMP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LQAQVRAPRLLQVQSQVSKKQQAQTQTSEPQDLDQVPEEFQGQDQVPEQQRQGQAPEQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 LQAQVRAPRLLQVQSQVSKKQQAQTQTSEPQDLDQVPEEFQGQDQVPEQQRQGQAPEQQQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 RHNQVPEQELEQNQAPEQPEVQEQAAEPAQAETEAEEPESLRVNAQVFLPLLSQDHHVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 RHNQVPEQELEQNQAPEQPEVQEQAAEPAQAETEAEEPESLRVNAQVFLPLLSQDHHVLL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 PLHLDTQVLIPVEGQTEGSPQAQAWTLEPPQAIGSVQALIEGLSRDLLRAPNSNNSKPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 PLHLDTQVLIPVEGQTEGSPQAQAWTLEPPQAIGSVQALIEGLSRDLLRAPNSNNSKPLG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 PLQTLMENLSSNRFYSQPEQAREKKSKVSTLRQALAKRLSPKRFRAKSSWRPEKLELSDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 PLQTLMENLSSNRFYSQPEQAREKKSKVSTLRQALAKRLSPKRFRAKSSWRPEKLELSDL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 EARRQRRQRRWEDIFNQHEEELRQVDKDKEDESSDNDEVFHSIQAEVQIEPLKPYISNPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 EARRQRRQRRWEDIFNQHEEELRQVDKDKEDESSDNDEVFHSIQAEVQIEPLKPYISNPK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 KIEVQERSPSVPNNQDHAHHVKFSSSVPQRSLLEQAQKPIDIRQRSSQNRQNWLAASESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 KIEVQERSPSVPNNQDHAHHVKFSSSVPQRSLLEQAQKPIDIRQRSSQNRQNWLAASESS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 SEEESPVTGRRSQSSPPYSTIDQKLLVDIHVPDGFKVGKISPPVYLTNEWVGYNALSEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 SEEESPVTGRRSQSSPPYSTIDQKLLVDIHVPDGFKVGKISPPVYLTNEWVGYNALSEIF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 RNDWLTPAPVIQPPEEDGDYVELYDASADTDGDDDDESNDTFEDTYDHANGNDDLDNQVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 RNDWLTPAPVIQPPEEDGDYVELYDASADTDGDDDDESNDTFEDTYDHANGNDDLDNQVD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 QANDVCKDHDDDNNKFVDDVNNNYYEAPSCPRASYGRDGSCKQDGYDGSRGKEEAYRGYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 QANDVCKDHDDDNNKFVDDVNNNYYEAPSCPRASYGRDGSCKQDGYDGSRGKEEAYRGYG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 SHTANRSHGGSAASEDNAAIGDQEEHAANIGSERRGSEGDGGKGVVRTSEESGALGLNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 SHTANRSHGGSAASEDNAAIGDQEEHAANIGSERRGSEGDGGKGVVRTSEESGALGLNGE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 ENCSETDGPGLKRPASQDFEYLQEEPGGGNEASNAIDSGAAPSAPDHESDNKDISESSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 ENCSETDGPGLKRPASQDFEYLQEEPGGGNEASNAIDSGAAPSAPDHESDNKDISESSTQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 SDFSANHSSPSKGSGMSADANFASAILYAGFVEVPEESPKQPSEVNVNPLYVSPACKKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 SDFSANHSSPSKGSGMSADANFASAILYAGFVEVPEESPKQPSEVNVNPLYVSPACKKPL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 IHMYEKEFTSEICCGSLWGVNLLLGTRSNLYLMDRSGKADITKLIRRRPFRQIQVLEPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 IHMYEKEFTSEICCGSLWGVNLLLGTRSNLYLMDRSGKADITKLIRRRPFRQIQVLEPLN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 LLITISGHKNRLRVYHLTWLRNKILNNDPESKRRQEEMLKTEEACKAIDKLTGCEHFSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 LLITISGHKNRLRVYHLTWLRNKILNNDPESKRRQEEMLKTEEACKAIDKLTGCEHFSVL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 QHEETTYIAIALKSSIHLYAWAPKSFDESTAIKVCIDQSADSEGDYMSYQAYIRILAKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 QHEETTYIAIALKSSIHLYAWAPKSFDESTAIKVCIDQSADSEGDYMSYQAYIRILAKIQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 AADPVNRFKRPDELLHLLKLKVFPTLDHKPVTVDLAIGSEKRLKIFFSSADGYHLIDAES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 AADPVNRFKRPDELLHLLKLKVFPTLDHKPVTVDLAIGSEKRLKIFFSSADGYHLIDAES
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 EVMSDVTLPKNPLEIIIPQNIIILPDCLGIGMMLTFNAEALSVEANEQLFKKILEMWKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 EVMSDVTLPKNPLEIIIPQNIIILPDCLGIGMMLTFNAEALSVEANEQLFKKILEMWKDI
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 PSSIAFECTQRTTGWGQKAIEVRSLQSRVLESELKRRSIKKLRFLCTRGDKLFFTSTLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_940 PSSIAFECTQRTTGWGQKAIEVRSLQSRVLESELKRRSIKKLRFLCTRGDKLFFTSTLRN
1510 1520 1530 1540 1550 1560
1570 1580
pF1KE3 HHSRVYFMTLGKLEELQSNYDV
::::::::::::::::::::::
NP_940 HHSRVYFMTLGKLEELQSNYDV
1570 1580
>>XP_006724695 (OMIM: 300791) PREDICTED: nik-related pro (1574 aa)
initn: 10021 init1: 9746 opt: 10518 Z-score: 3420.1 bits: 645.7 E(85289): 9.2e-184
Smith-Waterman score: 10518; 99.5% identity (99.5% similar) in 1582 aa overlap (1-1582:1-1574)
10 20 30 40 50 60
pF1KE3 MAGPGGWRDREVTDLGHLPDPTGIFSLDKTIGLGTYGRIYLGLHEKTGAFTAVKVMNARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAGPGGWRDREVTDLGHLPDPTGIFSLDKTIGLGTYGRIYLGLHEKTGAFTAVKVMNARK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QRHQLWMVMELCAAGSVTDVVRMTSNQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QRHQLWMVMELCAAGSVTDVVRMTSNQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 QNVLLTHNAEVKLVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QNVLLTHNAEVKLVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 WSVGITAIEMAEGAPPLCNLQPLEALFVILRESAPTVKSSGWSRKFHNFMEKCTIKNFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WSVGITAIEMAEGAPPLCNLQPLEALFVILRESAPTVKSSGWSRKFHNFMEKCTIKNFLF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 RPTSANMLQHPFVRDIKNERHVVESLTRHLTGIIKKRQKKGIPLIFEREEAIKEQYTVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RPTSANMLQHPFVRDIKNERHVVESLTRHLTGIIKKRQKKGIPLIFEREEAIKEQYTVRR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FRGPSCTHELLRLPTSSRCRPLRVLHGEPSQPRWLPDREEPQVQALQQLQGAARVFMPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FRGPSCTHELLRLPTSSRCRPLRVLHGEPSQPRWLPDREEPQVQALQQLQGAARVFMPLQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 ALDSAPKPLKGQAQAPQRLQGAARVFMPLQAQVKAKASKPLQMQIKAPPRLRRAARVLMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALDSAPKPLKGQAQAPQRLQGAARVFMPLQAQVKAKASKPLQMQIKAPPRLRRAARVLMP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LQAQVRAPRLLQVQSQVSKKQQAQTQTSEPQDLDQVPEEFQGQDQVPEQQRQGQAPEQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQAQVRAPRLLQVQSQVSKKQQAQTQTSEPQDLDQVPEEFQGQDQVPEQQRQGQAPEQQQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 RHNQVPEQELEQNQAPEQPEVQEQAAEPAQAETEAEEPESLRVNAQVFLPLLSQDHHVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RHNQVPEQELEQNQAPEQPEVQEQAAEPAQAETEAEEPESLRVNAQVFLPLLSQDHHVLL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 PLHLDTQVLIPVEGQTEGSPQAQAWTLEPPQAIGSVQALIEGLSRDLLRAPNSNNSKPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLHLDTQVLIPVEGQTEGSPQAQAWTLEPPQAIGSVQALIEGLSRDLLRAPNSNNSKPLG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 PLQTLMENLSSNRFYSQPEQAREKKSKVSTLRQALAKRLSPKRFRAKSSWRPEKLELSDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLQTLMENLSSNRFYSQPEQAREKKSKVSTLRQALAKRLSPKRFRAKSSWRPEKLELSDL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 EARRQRRQRRWEDIFNQHEEELRQVDKDKEDESSDNDEVFHSIQAEVQIEPLKPYISNPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EARRQRRQRRWEDIFNQHEEELRQVDKDKEDESSDNDEVFHSIQAEVQIEPLKPYISNPK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 KIEVQERSPSVPNNQDHAHHVKFSSSVPQRSLLEQAQKPIDIRQRSSQNRQNWLAASESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KIEVQERSPSVPNNQDHAHHVKFSSSVPQRSLLEQAQKPIDIRQRSSQNRQNWLAASESS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 SEEESPVTGRRSQSSPPYSTIDQKLLVDIHVPDGFKVGKISPPVYLTNEWVGYNALSEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEEESPVTGRRSQSSPPYSTIDQKLLVDIHVPDGFKVGKISPPVYLTNEWVGYNALSEIF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 RNDWLTPAPVIQPPEEDGDYVELYDASADTDGDDDDESNDTFEDTYDHANGNDDLDNQVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RNDWLTPAPVIQPPEEDGDYVELYDASADTDGDDDDESNDTFEDTYDHANGNDDLDNQVD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 QANDVCKDHDDDNNKFVDDVNNNYYEAPSCPRASYGRDGSCKQDGYDGSRGKEEAYRGYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QANDVCKDHDDDNNKFVDDVNNNYYEAPSCPRASYGRDGSCKQDGYDGSRGKEEAYRGYG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 SHTANRSHGGSAASEDNAAIGDQEEHAANIGSERRGSEGDGGKGVVRTSEESGALGLNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SHTANRSHGGSAASEDNAAIGDQEEHAANIGSERRGSEGDGGKGVVRTSEESGALGLNGE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 ENCSETDGPGLKRPASQDFEYLQEEPGGGNEASNAIDSGAAPSAPDHESDNKDISESSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENCSETDGPGLKRPASQDFEYLQEEPGGGNEASNAIDSGAAPSAPDHESDNKDISESSTQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 SDFSANHSSPSKGSGMSADANFASAILYAGFVEVPEESPKQPSEVNVNPLYVSPACKKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDFSANHSSPSKGSGMSADANFASAILYAGFVEVPEESPKQPSEVNVNPLYVSPACKKPL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 IHMYEKEFTSEICCGSLWGVNLLLGTRSNLYLMDRSGKADITKLIRRRPFRQIQVLEPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IHMYEKEFTSEICCGSLWGVNLLLGTRSNLYLMDRSGKADITKLIRRRPFRQIQVLEPLN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 LLITISGHKNRLRVYHLTWLRNKILNNDPESKRRQEEMLKTEEACKAIDKLTGCEHFSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLITISGHKNRLRVYHLTWLRNKILNNDPESKRRQEEMLKTEEACKAIDKLTGCEHFSVL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 QHEETTYIAIALKSSIHLYAWAPKSFDESTAIKVCIDQSADSEGDYMSYQAYIRILAKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QHEETTYIAIALKSSIHLYAWAPKSFDESTAIKVCIDQSADSEGDYMSYQAYIRILAKIQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 AADPVNRFKRPDELLHLLKLKVFPTLDHKPVTVDLAIGSEKRLKIFFSSADGYHLIDAES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AADPVNRFKRPDELLHLLKLKVFPTLDHKPVTVDLAIGSEKRLKIFFSSADGYHLIDAES
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 EVMSDVTLPKNPLEIIIPQNIIILPDCLGIGMMLTFNAEALSVEANEQLFKKILEMWKDI
::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_006 EVMSDVTLPKN--------NIIILPDCLGIGMMLTFNAEALSVEANEQLFKKILEMWKDI
1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KE3 PSSIAFECTQRTTGWGQKAIEVRSLQSRVLESELKRRSIKKLRFLCTRGDKLFFTSTLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSSIAFECTQRTTGWGQKAIEVRSLQSRVLESELKRRSIKKLRFLCTRGDKLFFTSTLRN
1500 1510 1520 1530 1540 1550
1570 1580
pF1KE3 HHSRVYFMTLGKLEELQSNYDV
::::::::::::::::::::::
XP_006 HHSRVYFMTLGKLEELQSNYDV
1560 1570
>>XP_011529189 (OMIM: 300791) PREDICTED: nik-related pro (1527 aa)
initn: 10220 init1: 10220 opt: 10220 Z-score: 3324.2 bits: 627.9 E(85289): 2e-178
Smith-Waterman score: 10220; 100.0% identity (100.0% similar) in 1527 aa overlap (56-1582:1-1527)
30 40 50 60 70 80
pF1KE3 SLDKTIGLGTYGRIYLGLHEKTGAFTAVKVMNARKTPLPEIGRRVRVNKYQKSVGWRYSD
::::::::::::::::::::::::::::::
XP_011 MNARKTPLPEIGRRVRVNKYQKSVGWRYSD
10 20 30
90 100 110 120 130 140
pF1KE3 EEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPGQRHQLWMVMELCAAGSVTDVVRMTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPGQRHQLWMVMELCAAGSVTDVVRMTS
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE3 NQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKGQNVLLTHNAEVKLVDFGVSAQVSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKGQNVLLTHNAEVKLVDFGVSAQVSRT
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE3 NGRRNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDVWSVGITAIEMAEGAPPLCNLQPLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGRRNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDVWSVGITAIEMAEGAPPLCNLQPLEA
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE3 LFVILRESAPTVKSSGWSRKFHNFMEKCTIKNFLFRPTSANMLQHPFVRDIKNERHVVES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFVILRESAPTVKSSGWSRKFHNFMEKCTIKNFLFRPTSANMLQHPFVRDIKNERHVVES
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE3 LTRHLTGIIKKRQKKGIPLIFEREEAIKEQYTVRRFRGPSCTHELLRLPTSSRCRPLRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTRHLTGIIKKRQKKGIPLIFEREEAIKEQYTVRRFRGPSCTHELLRLPTSSRCRPLRVL
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE3 HGEPSQPRWLPDREEPQVQALQQLQGAARVFMPLQALDSAPKPLKGQAQAPQRLQGAARV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGEPSQPRWLPDREEPQVQALQQLQGAARVFMPLQALDSAPKPLKGQAQAPQRLQGAARV
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE3 FMPLQAQVKAKASKPLQMQIKAPPRLRRAARVLMPLQAQVRAPRLLQVQSQVSKKQQAQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMPLQAQVKAKASKPLQMQIKAPPRLRRAARVLMPLQAQVRAPRLLQVQSQVSKKQQAQT
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE3 QTSEPQDLDQVPEEFQGQDQVPEQQRQGQAPEQQQRHNQVPEQELEQNQAPEQPEVQEQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTSEPQDLDQVPEEFQGQDQVPEQQRQGQAPEQQQRHNQVPEQELEQNQAPEQPEVQEQA
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE3 AEPAQAETEAEEPESLRVNAQVFLPLLSQDHHVLLPLHLDTQVLIPVEGQTEGSPQAQAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEPAQAETEAEEPESLRVNAQVFLPLLSQDHHVLLPLHLDTQVLIPVEGQTEGSPQAQAW
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE3 TLEPPQAIGSVQALIEGLSRDLLRAPNSNNSKPLGPLQTLMENLSSNRFYSQPEQAREKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLEPPQAIGSVQALIEGLSRDLLRAPNSNNSKPLGPLQTLMENLSSNRFYSQPEQAREKK
580 590 600 610 620 630
690 700 710 720 730 740
pF1KE3 SKVSTLRQALAKRLSPKRFRAKSSWRPEKLELSDLEARRQRRQRRWEDIFNQHEEELRQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKVSTLRQALAKRLSPKRFRAKSSWRPEKLELSDLEARRQRRQRRWEDIFNQHEEELRQV
640 650 660 670 680 690
750 760 770 780 790 800
pF1KE3 DKDKEDESSDNDEVFHSIQAEVQIEPLKPYISNPKKIEVQERSPSVPNNQDHAHHVKFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DKDKEDESSDNDEVFHSIQAEVQIEPLKPYISNPKKIEVQERSPSVPNNQDHAHHVKFSS
700 710 720 730 740 750
810 820 830 840 850 860
pF1KE3 SVPQRSLLEQAQKPIDIRQRSSQNRQNWLAASESSSEEESPVTGRRSQSSPPYSTIDQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVPQRSLLEQAQKPIDIRQRSSQNRQNWLAASESSSEEESPVTGRRSQSSPPYSTIDQKL
760 770 780 790 800 810
870 880 890 900 910 920
pF1KE3 LVDIHVPDGFKVGKISPPVYLTNEWVGYNALSEIFRNDWLTPAPVIQPPEEDGDYVELYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVDIHVPDGFKVGKISPPVYLTNEWVGYNALSEIFRNDWLTPAPVIQPPEEDGDYVELYD
820 830 840 850 860 870
930 940 950 960 970 980
pF1KE3 ASADTDGDDDDESNDTFEDTYDHANGNDDLDNQVDQANDVCKDHDDDNNKFVDDVNNNYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASADTDGDDDDESNDTFEDTYDHANGNDDLDNQVDQANDVCKDHDDDNNKFVDDVNNNYY
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KE3 EAPSCPRASYGRDGSCKQDGYDGSRGKEEAYRGYGSHTANRSHGGSAASEDNAAIGDQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAPSCPRASYGRDGSCKQDGYDGSRGKEEAYRGYGSHTANRSHGGSAASEDNAAIGDQEE
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KE3 HAANIGSERRGSEGDGGKGVVRTSEESGALGLNGEENCSETDGPGLKRPASQDFEYLQEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HAANIGSERRGSEGDGGKGVVRTSEESGALGLNGEENCSETDGPGLKRPASQDFEYLQEE
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150 1160
pF1KE3 PGGGNEASNAIDSGAAPSAPDHESDNKDISESSTQSDFSANHSSPSKGSGMSADANFASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGGGNEASNAIDSGAAPSAPDHESDNKDISESSTQSDFSANHSSPSKGSGMSADANFASA
1060 1070 1080 1090 1100 1110
1170 1180 1190 1200 1210 1220
pF1KE3 ILYAGFVEVPEESPKQPSEVNVNPLYVSPACKKPLIHMYEKEFTSEICCGSLWGVNLLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ILYAGFVEVPEESPKQPSEVNVNPLYVSPACKKPLIHMYEKEFTSEICCGSLWGVNLLLG
1120 1130 1140 1150 1160 1170
1230 1240 1250 1260 1270 1280
pF1KE3 TRSNLYLMDRSGKADITKLIRRRPFRQIQVLEPLNLLITISGHKNRLRVYHLTWLRNKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRSNLYLMDRSGKADITKLIRRRPFRQIQVLEPLNLLITISGHKNRLRVYHLTWLRNKIL
1180 1190 1200 1210 1220 1230
1290 1300 1310 1320 1330 1340
pF1KE3 NNDPESKRRQEEMLKTEEACKAIDKLTGCEHFSVLQHEETTYIAIALKSSIHLYAWAPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NNDPESKRRQEEMLKTEEACKAIDKLTGCEHFSVLQHEETTYIAIALKSSIHLYAWAPKS
1240 1250 1260 1270 1280 1290
1350 1360 1370 1380 1390 1400
pF1KE3 FDESTAIKVCIDQSADSEGDYMSYQAYIRILAKIQAADPVNRFKRPDELLHLLKLKVFPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDESTAIKVCIDQSADSEGDYMSYQAYIRILAKIQAADPVNRFKRPDELLHLLKLKVFPT
1300 1310 1320 1330 1340 1350
1410 1420 1430 1440 1450 1460
pF1KE3 LDHKPVTVDLAIGSEKRLKIFFSSADGYHLIDAESEVMSDVTLPKNPLEIIIPQNIIILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDHKPVTVDLAIGSEKRLKIFFSSADGYHLIDAESEVMSDVTLPKNPLEIIIPQNIIILP
1360 1370 1380 1390 1400 1410
1470 1480 1490 1500 1510 1520
pF1KE3 DCLGIGMMLTFNAEALSVEANEQLFKKILEMWKDIPSSIAFECTQRTTGWGQKAIEVRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCLGIGMMLTFNAEALSVEANEQLFKKILEMWKDIPSSIAFECTQRTTGWGQKAIEVRSL
1420 1430 1440 1450 1460 1470
1530 1540 1550 1560 1570 1580
pF1KE3 QSRVLESELKRRSIKKLRFLCTRGDKLFFTSTLRNHHSRVYFMTLGKLEELQSNYDV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSRVLESELKRRSIKKLRFLCTRGDKLFFTSTLRNHHSRVYFMTLGKLEELQSNYDV
1480 1490 1500 1510 1520
>>XP_006724697 (OMIM: 300791) PREDICTED: nik-related pro (1526 aa)
initn: 9899 init1: 9112 opt: 9112 Z-score: 2967.2 bits: 561.8 E(85289): 1.5e-158
Smith-Waterman score: 10097; 96.5% identity (96.5% similar) in 1582 aa overlap (1-1582:1-1526)
10 20 30 40 50 60
pF1KE3 MAGPGGWRDREVTDLGHLPDPTGIFSLDKTIGLGTYGRIYLGLHEKTGAFTAVKVMNARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAGPGGWRDREVTDLGHLPDPTGIFSLDKTIGLGTYGRIYLGLHEKTGAFTAVKVMNARK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QRHQLWMVMELCAAGSVTDVVRMTSNQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QRHQLWMVMELCAAGSVTDVVRMTSNQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 QNVLLTHNAEVKLVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QNVLLTHNAEVKLVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 WSVGITAIEMAEGAPPLCNLQPLEALFVILRESAPTVKSSGWSRKFHNFMEKCTIKNFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WSVGITAIEMAEGAPPLCNLQPLEALFVILRESAPTVKSSGWSRKFHNFMEKCTIKNFLF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 RPTSANMLQHPFVRDIKNERHVVESLTRHLTGIIKKRQKKGIPLIFEREEAIKEQYTVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RPTSANMLQHPFVRDIKNERHVVESLTRHLTGIIKKRQKKGIPLIFEREEAIKEQYTVRR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FRGPSCTHELLRLPTSSRCRPLRVLHGEPSQPRWLPDREEPQVQALQQLQGAARVFMPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FRGPSCTHELLRLPTSSRCRPLRVLHGEPSQPRWLPDREEPQVQALQQLQGAARVFMPLQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 ALDSAPKPLKGQAQAPQRLQGAARVFMPLQAQVKAKASKPLQMQIKAPPRLRRAARVLMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALDSAPKPLKGQAQAPQRLQGAARVFMPLQAQVKAKASKPLQMQIKAPPRLRRAARVLMP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LQAQVRAPRLLQVQSQVSKKQQAQTQTSEPQDLDQVPEEFQGQDQVPEQQRQGQAPEQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQAQVRAPRLLQVQSQVSKKQQAQTQTSEPQDLDQVPEEFQGQDQVPEQQRQGQAPEQQQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 RHNQVPEQELEQNQAPEQPEVQEQAAEPAQAETEAEEPESLRVNAQVFLPLLSQDHHVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RHNQVPEQELEQNQAPEQPEVQEQAAEPAQAETEAEEPESLRVNAQVFLPLLSQDHHVLL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 PLHLDTQVLIPVEGQTEGSPQAQAWTLEPPQAIGSVQALIEGLSRDLLRAPNSNNSKPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLHLDTQVLIPVEGQTEGSPQAQAWTLEPPQAIGSVQALIEGLSRDLLRAPNSNNSKPLG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 PLQTLMENLSSNRFYSQPEQAREKKSKVSTLRQALAKRLSPKRFRAKSSWRPEKLELSDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLQTLMENLSSNRFYSQPEQAREKKSKVSTLRQALAKRLSPKRFRAKSSWRPEKLELSDL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 EARRQRRQRRWEDIFNQHEEELRQVDKDKEDESSDNDEVFHSIQAEVQIEPLKPYISNPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EARRQRRQRRWEDIFNQHEEELRQVDKDKEDESSDNDEVFHSIQAEVQIEPLKPYISNPK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 KIEVQERSPSVPNNQDHAHHVKFSSSVPQRSLLEQAQKPIDIRQRSSQNRQNWLAASESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KIEVQERSPSVPNNQDHAHHVKFSSSVPQRSLLEQAQKPIDIRQRSSQNRQNWLAASESS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 SEEESPVTGRRSQSSPPYSTIDQKLLVDIHVPDGFKVGKISPPVYLTNEWVGYNALSEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEEESPVTGRRSQSSPPYSTIDQKLLVDIHVPDGFKVGKISPPVYLTNEWVGYNALSEIF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 RNDWLTPAPVIQPPEEDGDYVELYDASADTDGDDDDESNDTFEDTYDHANGNDDLDNQVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RNDWLTPAPVIQPPEEDGDYVELYDASADTDGDDDDESNDTFEDTYDHANGNDDLDNQVD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 QANDVCKDHDDDNNKFVDDVNNNYYEAPSCPRASYGRDGSCKQDGYDGSRGKEEAYRGYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QANDVCKDHDDDNNKFVDDVNNNYYEAPSCPRASYGRDGSCKQDGYDGSRGKEEAYRGYG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 SHTANRSHGGSAASEDNAAIGDQEEHAANIGSERRGSEGDGGKGVVRTSEESGALGLNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SHTANRSHGGSAASEDNAAIGDQEEHAANIGSERRGSEGDGGKGVVRTSEESGALGLNGE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 ENCSETDGPGLKRPASQDFEYLQEEPGGGNEASNAIDSGAAPSAPDHESDNKDISESSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENCSETDGPGLKRPASQDFEYLQEEPGGGNEASNAIDSGAAPSAPDHESDNKDISESSTQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 SDFSANHSSPSKGSGMSADANFASAILYAGFVEVPEESPKQPSEVNVNPLYVSPACKKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDFSANHSSPSKGSGMSADANFASAILYAGFVEVPEESPKQPSEVNVNPLYVSPACKKPL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 IHMYEKEFTSEICCGSLWGVNLLLGTRSNLYLMDRSGKADITKLIRRRPFRQIQVLEPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IHMYEKEFTSEICCGSLWGVNLLLGTRSNLYLMDRSGKADITKLIRRRPFRQIQVLEPLN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 LLITISGHKNRLRVYHLTWLRNKILNNDPESKRRQEEMLKTEEACKAIDKLTGCEHFSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLITISGHKNRLRVYHLTWLRNKILNNDPESKRRQEEMLKTEEACKAIDKLTGCEHFSVL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 QHEETTYIAIALKSSIHLYAWAPKSFDESTAIKVCIDQSADSEGDYMSYQAYIRILAKIQ
::::::::::::::::::::::::::::::::::
XP_006 QHEETTYIAIALKSSIHLYAWAPKSFDESTAIKV--------------------------
1330 1340 1350
1390 1400 1410 1420 1430 1440
pF1KE3 AADPVNRFKRPDELLHLLKLKVFPTLDHKPVTVDLAIGSEKRLKIFFSSADGYHLIDAES
::::::::::::::::::::::::::::::::::::::
XP_006 ----------------------FPTLDHKPVTVDLAIGSEKRLKIFFSSADGYHLIDAES
1360 1370 1380 1390
1450 1460 1470 1480 1490 1500
pF1KE3 EVMSDVTLPKNPLEIIIPQNIIILPDCLGIGMMLTFNAEALSVEANEQLFKKILEMWKDI
::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_006 EVMSDVTLPKN--------NIIILPDCLGIGMMLTFNAEALSVEANEQLFKKILEMWKDI
1400 1410 1420 1430 1440
1510 1520 1530 1540 1550 1560
pF1KE3 PSSIAFECTQRTTGWGQKAIEVRSLQSRVLESELKRRSIKKLRFLCTRGDKLFFTSTLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSSIAFECTQRTTGWGQKAIEVRSLQSRVLESELKRRSIKKLRFLCTRGDKLFFTSTLRN
1450 1460 1470 1480 1490 1500
1570 1580
pF1KE3 HHSRVYFMTLGKLEELQSNYDV
::::::::::::::::::::::
XP_006 HHSRVYFMTLGKLEELQSNYDV
1510 1520
>>XP_006724696 (OMIM: 300791) PREDICTED: nik-related pro (1534 aa)
initn: 9112 init1: 9112 opt: 9112 Z-score: 2967.2 bits: 561.8 E(85289): 1.6e-158
Smith-Waterman score: 10176; 97.0% identity (97.0% similar) in 1582 aa overlap (1-1582:1-1534)
10 20 30 40 50 60
pF1KE3 MAGPGGWRDREVTDLGHLPDPTGIFSLDKTIGLGTYGRIYLGLHEKTGAFTAVKVMNARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAGPGGWRDREVTDLGHLPDPTGIFSLDKTIGLGTYGRIYLGLHEKTGAFTAVKVMNARK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QRHQLWMVMELCAAGSVTDVVRMTSNQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QRHQLWMVMELCAAGSVTDVVRMTSNQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 QNVLLTHNAEVKLVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QNVLLTHNAEVKLVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 WSVGITAIEMAEGAPPLCNLQPLEALFVILRESAPTVKSSGWSRKFHNFMEKCTIKNFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WSVGITAIEMAEGAPPLCNLQPLEALFVILRESAPTVKSSGWSRKFHNFMEKCTIKNFLF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 RPTSANMLQHPFVRDIKNERHVVESLTRHLTGIIKKRQKKGIPLIFEREEAIKEQYTVRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RPTSANMLQHPFVRDIKNERHVVESLTRHLTGIIKKRQKKGIPLIFEREEAIKEQYTVRR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FRGPSCTHELLRLPTSSRCRPLRVLHGEPSQPRWLPDREEPQVQALQQLQGAARVFMPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FRGPSCTHELLRLPTSSRCRPLRVLHGEPSQPRWLPDREEPQVQALQQLQGAARVFMPLQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 ALDSAPKPLKGQAQAPQRLQGAARVFMPLQAQVKAKASKPLQMQIKAPPRLRRAARVLMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALDSAPKPLKGQAQAPQRLQGAARVFMPLQAQVKAKASKPLQMQIKAPPRLRRAARVLMP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LQAQVRAPRLLQVQSQVSKKQQAQTQTSEPQDLDQVPEEFQGQDQVPEQQRQGQAPEQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQAQVRAPRLLQVQSQVSKKQQAQTQTSEPQDLDQVPEEFQGQDQVPEQQRQGQAPEQQQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 RHNQVPEQELEQNQAPEQPEVQEQAAEPAQAETEAEEPESLRVNAQVFLPLLSQDHHVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RHNQVPEQELEQNQAPEQPEVQEQAAEPAQAETEAEEPESLRVNAQVFLPLLSQDHHVLL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 PLHLDTQVLIPVEGQTEGSPQAQAWTLEPPQAIGSVQALIEGLSRDLLRAPNSNNSKPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLHLDTQVLIPVEGQTEGSPQAQAWTLEPPQAIGSVQALIEGLSRDLLRAPNSNNSKPLG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 PLQTLMENLSSNRFYSQPEQAREKKSKVSTLRQALAKRLSPKRFRAKSSWRPEKLELSDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLQTLMENLSSNRFYSQPEQAREKKSKVSTLRQALAKRLSPKRFRAKSSWRPEKLELSDL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 EARRQRRQRRWEDIFNQHEEELRQVDKDKEDESSDNDEVFHSIQAEVQIEPLKPYISNPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EARRQRRQRRWEDIFNQHEEELRQVDKDKEDESSDNDEVFHSIQAEVQIEPLKPYISNPK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 KIEVQERSPSVPNNQDHAHHVKFSSSVPQRSLLEQAQKPIDIRQRSSQNRQNWLAASESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KIEVQERSPSVPNNQDHAHHVKFSSSVPQRSLLEQAQKPIDIRQRSSQNRQNWLAASESS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 SEEESPVTGRRSQSSPPYSTIDQKLLVDIHVPDGFKVGKISPPVYLTNEWVGYNALSEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEEESPVTGRRSQSSPPYSTIDQKLLVDIHVPDGFKVGKISPPVYLTNEWVGYNALSEIF
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 RNDWLTPAPVIQPPEEDGDYVELYDASADTDGDDDDESNDTFEDTYDHANGNDDLDNQVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RNDWLTPAPVIQPPEEDGDYVELYDASADTDGDDDDESNDTFEDTYDHANGNDDLDNQVD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 QANDVCKDHDDDNNKFVDDVNNNYYEAPSCPRASYGRDGSCKQDGYDGSRGKEEAYRGYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QANDVCKDHDDDNNKFVDDVNNNYYEAPSCPRASYGRDGSCKQDGYDGSRGKEEAYRGYG
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 SHTANRSHGGSAASEDNAAIGDQEEHAANIGSERRGSEGDGGKGVVRTSEESGALGLNGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SHTANRSHGGSAASEDNAAIGDQEEHAANIGSERRGSEGDGGKGVVRTSEESGALGLNGE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 ENCSETDGPGLKRPASQDFEYLQEEPGGGNEASNAIDSGAAPSAPDHESDNKDISESSTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENCSETDGPGLKRPASQDFEYLQEEPGGGNEASNAIDSGAAPSAPDHESDNKDISESSTQ
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 SDFSANHSSPSKGSGMSADANFASAILYAGFVEVPEESPKQPSEVNVNPLYVSPACKKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDFSANHSSPSKGSGMSADANFASAILYAGFVEVPEESPKQPSEVNVNPLYVSPACKKPL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 IHMYEKEFTSEICCGSLWGVNLLLGTRSNLYLMDRSGKADITKLIRRRPFRQIQVLEPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IHMYEKEFTSEICCGSLWGVNLLLGTRSNLYLMDRSGKADITKLIRRRPFRQIQVLEPLN
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 LLITISGHKNRLRVYHLTWLRNKILNNDPESKRRQEEMLKTEEACKAIDKLTGCEHFSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLITISGHKNRLRVYHLTWLRNKILNNDPESKRRQEEMLKTEEACKAIDKLTGCEHFSVL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 QHEETTYIAIALKSSIHLYAWAPKSFDESTAIKVCIDQSADSEGDYMSYQAYIRILAKIQ
::::::::::::::::::::::::::::::::::
XP_006 QHEETTYIAIALKSSIHLYAWAPKSFDESTAIKV--------------------------
1330 1340 1350
1390 1400 1410 1420 1430 1440
pF1KE3 AADPVNRFKRPDELLHLLKLKVFPTLDHKPVTVDLAIGSEKRLKIFFSSADGYHLIDAES
::::::::::::::::::::::::::::::::::::::
XP_006 ----------------------FPTLDHKPVTVDLAIGSEKRLKIFFSSADGYHLIDAES
1360 1370 1380 1390
1450 1460 1470 1480 1490 1500
pF1KE3 EVMSDVTLPKNPLEIIIPQNIIILPDCLGIGMMLTFNAEALSVEANEQLFKKILEMWKDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVMSDVTLPKNPLEIIIPQNIIILPDCLGIGMMLTFNAEALSVEANEQLFKKILEMWKDI
1400 1410 1420 1430 1440 1450
1510 1520 1530 1540 1550 1560
pF1KE3 PSSIAFECTQRTTGWGQKAIEVRSLQSRVLESELKRRSIKKLRFLCTRGDKLFFTSTLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PSSIAFECTQRTTGWGQKAIEVRSLQSRVLESELKRRSIKKLRFLCTRGDKLFFTSTLRN
1460 1470 1480 1490 1500 1510
1570 1580
pF1KE3 HHSRVYFMTLGKLEELQSNYDV
::::::::::::::::::::::
XP_006 HHSRVYFMTLGKLEELQSNYDV
1520 1530
>>XP_016880194 (OMIM: 609426) PREDICTED: misshapen-like (1341 aa)
initn: 2179 init1: 1175 opt: 1309 Z-score: 453.5 bits: 96.5 E(85289): 1.6e-18
Smith-Waterman score: 2204; 32.0% identity (56.6% similar) in 1579 aa overlap (1-1572:1-1335)
10 20 30 40 50 60
pF1KE3 MAGPGGWRDREVTDLGHLPDPTGIFSLDKTIGLGTYGRIYLGLHEKTGAFTAVKVMNARK
:. :. :. . ::. : ::.::: : ...: ::::..: : : ::: ..:.:::.. .
XP_016 MGDPAPARSLDDIDLSALRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPG
::::... :.:.:.::: :.::...::::.: ::::
XP_016 ------------------------DEEEEIKQEINMLKKYSHHRNIATYYGAFIKKSPPG
70 80 90
130 140 150 160 170 180
pF1KE3 QRHQLWMVMELCAAGSVTDVVRMTSNQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKG
. :::.:::.:.::::::.:. :....:::: :::::::::.::::::::.::::::::
XP_016 NDDQLWLVMEFCGAGSVTDLVKNTKGNALKEDCIAYICREILRGLAHLHAHKVIHRDIKG
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 QNVLLTHNAEVKLVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDV
::::::.::::::::::::::..:: ::::.::::::::::::: :::.: .::::::.
XP_016 QNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDI
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 WSVGITAIEMAEGAPPLCNLQPLEALFVILRESAPTVKSSGWSRKFHNFMEKCTIKNFLF
::.:::::::::::::::...:..:::.: :. : .::. ::.:: .:.. : ::..:
XP_016 WSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFIDFIDTCLIKTYLS
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE3 RPTSANMLQHPFVRDIKNERHVVESLTRHLTGIIKKRQKKGIPLIFEREEAIKEQYTVRR
:: . ..:. ::.:: .::.: .: :. ..:.:.: :.::. . .:. .
XP_016 RPPTEQLLKFPFIRDQPTERQVRIQLKDHID---RSRKKRG-----EKEET-EYEYSGSE
280 290 300 310 320
370 380 390 400 410 420
pF1KE3 FRGPSCTHELLRLPTSSRCRPLRVLHGEPSQPRWLPDREEPQVQALQQLQGAARVFMPLQ
. : ::: ..: . . : ..:. : :. ::
XP_016 EEDDS--------------------HGEEGEPSSIMN--VPGESTLR------REFLRLQ
330 340 350
430 440 450 460 470
pF1KE3 ALD-SAPKPLKGQAQAPQRLQGAARVFMPLQAQVKAKASKPLQMQIKAPPRLRRAARVLM
. : . :: : : :. : : .:..: . : .:. . :: ::
XP_016 QENKSNSEALKQQQQLQQQQQRD-----P-EAHIKHLLHQR-QRRIEEQKEERR--RV--
360 370 380 390 400
480 490 500 510 520 530
pF1KE3 PLQAQVRAPRLLQVQSQVSKKQQAQTQTSEPQDLDQVPEEFQGQDQVPEQQRQGQAPEQQ
. : : : : ....:.: : . . : : . :. :.. ::. . :..
XP_016 --EEQQRRERE---QRKLQEKEQ-QRRLEDMQALRREEERRQAER---EQEYIRHRLEEE
410 420 430 440 450
540 550 560 570 580 590
pF1KE3 QRHNQVPEQELEQNQAPEQPEVQEQAAEPAQAETEAEEPESLRVNAQVFLPLLSQDHHVL
::. .. .:.: :.:: ..: : :.: :.. : :.:.: :
XP_016 QRQLEILQQQLLQEQALLLEYKRKQLEEQRQSE---------RLQRQ-----LQQEHAYL
460 470 480 490 500
600 610 620 630 640 650
pF1KE3 LPLHLDTQVLIPVEGQTEGSPQAQAWTLEPPQAIGSVQALIEGLSRDLLRAPNSNNSKPL
:. . : : . . : : : :. : : : : . .. .
XP_016 KSLQQQQQ-------QQQLQKQQQ-------------QQLLPG---D--RKPLYHYGRGM
510 520 530 540
660 670 680 690 700 710
pF1KE3 GPLQTLMENLSSNRFYSQPEQAREKKSKVSTLRQALAKRLSPKRFRAKSSWRPEKLELSD
.: .. . : :..: .:.. : : .. .:. ..: : ::.
XP_016 NP----ADKPAWAREVE--ERTRMNKQQNSPLAKSKPGSTGPEPPIPQASPGPPG-PLSQ
550 560 570 580 590
720 730 740 750 760 770
pF1KE3 LEARRQRRQRRWEDIFNQHEEELRQVDKDKEDESSDNDEVFHSIQAEVQIEPLKPYISNP
:: : . : :. .:. . : .: . . .: : : :
XP_016 TPPM----QRPVEPQEGPH--------KSLQDQPTRNLAAFPASH-----DP-DPAIPAP
600 610 620 630
780 790 800 810 820 830
pF1KE3 KKIEVQERSPSVPNNQDHAHHVKFSSSVPQRSLLEQAQKPIDIRQRSSQNRQNWLAASES
. :. . .:.: . . : : . . . : . ::.:. ... .
XP_016 TATP-SARGAVIRQNSDPTSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTSGAG
640 650 660 670 680 690
840 850 860 870 880 890
pF1KE3 SSEEESPVTGRRSQSSPPYSTIDQKLLVDIHVPDGFKVGKISPPVYLTNEWVGYNALSEI
.:. . : .: ..: .... : : . .:: .: ..
XP_016 GSRPAQAVRARPRSNSAWQIYLQRRAERGTPKPPGPPAQPPGPPNASSN--------PDL
700 710 720 730 740
900 910 920 930 940 950
pF1KE3 FRND--WLTPAPVIQPPEEDGDYVELYDASADTDGDDDDESNDTFEDTYDHANGNDDLDN
:.: : :. : : . . . : .. ... . ..:. :: .
XP_016 RRSDPGWERSDSVL--PASHGHLPQAGSLERNRVGVSSKPDSSPVLSPGNKAKP-DDHRS
750 760 770 780 790 800
960 970 980 990 1000 1010
pF1KE3 QVDQANDVCKDHDDDNNKFVDDVNNNYYEAPSCPRASYGRDGSCKQDGYDGSRGKEEAYR
. . : :: . . ::: :. .. : : ... ..:. :: .
XP_016 RPGRPAD-----------FVLLKERTLDEAPRPPKKAM--DYSSSSEEVESSEDDEEEGE
810 820 830 840 850
1020 1030 1040 1050 1060 1070
pF1KE3 GYGSHTANRSHGGSAASEDNAAIGDQEEHAANIGSERRGSEGDGGKGVVRTSEESGALGL
: : ..:. :. .. :. ... . : .. . . : : : :: :: : :
XP_016 G-GPAEGSRDTPGGRSDGDTDSVSTMVVHDVEEITGTQPPYGGGTMVVQRTPEEERNL-L
860 870 880 890 900
1080 1090 1100 1110 1120 1130
pF1KE3 NGEENCSETDGPGLKRPASQDFEYLQEEPGGGNEASNAIDSGAAPSAPDHESD--NKDIS
... : . :. : . .:. . : ..: .: . : .: .. .
XP_016 HADSN-GYTNLPDVVQPSHSPTEN---------------SKGQSPPSKDGSGDYQSRGLV
910 920 930 940 950
1140 1150 1160 1170 1180 1190
pF1KE3 ESSTQSDFSANHSSPSKGSGMSADANFASAILYAGFVEVPE--ESPKQPSEVNVNPLYVS
.. .:.:. . : :.:. .:.. . ... . . .. : ::::: .
XP_016 KAPGKSSFTMFVDLGIYQPGGSGDSIPITALVGGEGTRLDQLQYDVRKGSVVNVNPTNTR
960 970 980 990 1000 1010
1200 1210 1220 1230 1240 1250
pF1KE3 PACKKPLIHMYEKEFTSEICCGSLWGVNLLLGTRSNLYLMDRSGKADITKLIRRRPFRQI
. : :. :.:.:.::: :..:::::::.::...:.:.::::.. . :: :: :.:.
XP_016 AHSETPEIRKYKKRFNSEILCAALWGVNLLVGTENGLMLLDRSGQGKVYGLIGRRRFQQM
1020 1030 1040 1050 1060 1070
1260 1270 1280 1290 1300 1310
pF1KE3 QVLEPLNLLITISGHKNRLRVYHLTWLRNKILNNDPESKRRQEEMLKTEEACKAIDKLTG
.::: :::::::::..:.::::.:.:::::::.:::: ...: . .. . :
XP_016 DVLEGLNLLITISGKRNKLRVYYLSWLRNKILHNDPEVEKKQ--------GWTTVGDMEG
1080 1090 1100 1110 1120
1320 1330 1340 1350 1360 1370
pF1KE3 CEHFSVLQHEETTYIAIALKSSIHLYAWAPKSFDESTAIKVCIDQSADSEGDYMSYQAYI
: :. :...:. ...::::::...::::::
XP_016 CGHYRVVKYERIKFLVIALKSSVEVYAWAPK-----------------------------
1130 1140 1150
1380 1390 1400 1410 1420 1430
pF1KE3 RILAKIQAADPVNRFKRPDELLHLLKLKVFPTLDHKPVTVDLAIGSEKRLKIFFSSADGY
: ..: . .: : : :.:. :::.. .:::....:. :.
XP_016 ----------PYHKF---------MAFKSFADLPHRPLLVDLTVEEGQRLKVIYGSSAGF
1160 1170 1180 1190
1440 1450 1460 1470 1480 1490
pF1KE3 HLIDAESEVMSDVTLPKNPLEIIIPQNIIILPDCLGIGMMLTFNAEALSVEANEQLFKKI
: .:..: :. .: . : :. ::.::. :. :.: .. :.. :.. ...: .
XP_016 HAVDVDSGNSYDIYIPVHIQSQITPHAIIFLPNTDGMEMLLCYEDEGVYVNTYGRIIKDV
1200 1210 1220 1230 1240 1250
1500 1510 1520 1530 1540 1550
pF1KE3 LEMWKDIPSSIAFECTQRTTGWGQKAIEVRSLQSRVLESELKRRSIKKLRFLCTRGDKLF
. .: ..:.:.:. :... :::.::::.::... :.. . .. ..:.::: :.::.:
XP_016 VLQWGEMPTSVAYICSNQIMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERNDKVF
1260 1270 1280 1290 1300 1310
1560 1570 1580
pF1KE3 FTSTLRNHHSRVYFMTLGKLEELQSNYDV
:.:. . :.::::::..
XP_016 FASVRSGGSSQVYFMTLNRNCIMNW
1320 1330 1340
>>XP_005264125 (OMIM: 604666) PREDICTED: mitogen-activat (1227 aa)
initn: 2156 init1: 1199 opt: 1301 Z-score: 451.2 bits: 96.0 E(85289): 2.1e-18
Smith-Waterman score: 2039; 31.5% identity (55.3% similar) in 1576 aa overlap (14-1572:14-1221)
10 20 30 40 50 60
pF1KE3 MAGPGGWRDREVTDLGHLPDPTGIFSLDKTIGLGTYGRIYLGLHEKTGAFTAVKVMNARK
::. : ::.::: : ...: ::::..: : : ::: ..:.:::.. .
XP_005 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPG
::::... :.:.:.::: :.::...::::.: ::::
XP_005 ------------------------DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPG
70 80 90
130 140 150 160 170 180
pF1KE3 QRHQLWMVMELCAAGSVTDVVRMTSNQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKG
. :::.:::.:.:::.::.:. :....::::::::: ::::.:::::: :.::::::::
XP_005 HDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKG
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 QNVLLTHNAEVKLVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDV
::::::.::::::::::::::..:: ::::.::::::::::::: :::.: .::::::.
XP_005 QNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 WSVGITAIEMAEGAPPLCNLQPLEALFVILRESAPTVKSSGWSRKFHNFMEKCTIKNFLF
:: :::::::::::::::...:..:::.: :. : .::. ::.:: .:.: : .::..
XP_005 WSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE3 RPTSANMLQHPFVRDIKNERHVVESLTRHLTGIIKKRQKKGIPLIFEREEAIKEQYTVRR
::.. ..:.:::.:: :::.: .: :. . :.:.: :..: : .
XP_005 RPSTEQLLKHPFIRDQPNERQVRIQLKDHID---RTRKKRG-----EKDE------TEYE
280 290 300 310 320
370 380 390 400 410 420
pF1KE3 FRGPSCTHELLRLPTSSRCRPLRVLHGEPSQPRWLPDREEPQVQALQQLQGAARVFMPLQ
. : .: ..: . .::::. .: : .. : :. ::
XP_005 YSGSEEEEE--EVPEQ---------EGEPSSIVNVPG--ESTLR---------RDFLRLQ
330 340 350 360
430 440 450 460 470 480
pF1KE3 ALDSAPKPLKGQAQAPQRLQGAARVFMPLQAQVKAKASKPLQMQIKAPPRLRRAARVLMP
. : ...: .: : . . : . : . : .:. . ::
XP_005 QEN------KERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRR------
370 380 390 400
490 500 510 520 530 540
pF1KE3 LQAQVRAPRLLQVQSQVSKKQQAQTQTSEPQDLDQVPEEFQGQDQVPEQQRQGQAPEQQQ
:. : : : ...:: . : . :. . ::.. . . :..:. : :...
XP_005 LEEQQRRERE-------ARRQQEREQRRREQEEKRRLEELERRRKEEEERRR--AEEEKR
410 420 430 440 450
550 560 570 580 590 600
pF1KE3 RHNQVPEQELEQNQAPEQPEVQEQAAEPAQAETEAEEPESLRVNAQVFLPLLSQDHHVLL
: .. ::: . : :. : . :. . . :. .: .: .::.
XP_005 RVER--EQEYIRRQLEEE-----------QRHLEVLQQQLLQEQA-----MLLHDHRRPH
460 470 480 490 500
610 620 630 640 650 660
pF1KE3 PLHLDTQVLIPVEGQTEGSPQAQAWTLEPPQAIGSVQALIEGLSRDLLRAPNSNNSKPLG
: : .. : ::: . :. ..:: .:
XP_005 PQH------------SQQPP--------PPQ---------QERSKPSFHAP-----EP--
510 520
670 680 690 700 710
pF1KE3 PLQTLMENLSSNRFYSQPEQAREKKSKVSTLRQALAKRLSPKRFRAK-SSWRPEKLELSD
. : ..::: .... .:..: :: . .. .: .. :.
XP_005 -----------KAHYEPADRAREVPVRTTSRSPVLSRRDSPLQGSGQQNSQAGQRNSTSS
530 540 550 560 570
720 730 740 750 760 770
pF1KE3 LEARRQRRQRRWEDIFNQHEEELRQVDKDKEDESSDNDEVFHSIQAEVQIEPLKPYISNP
.: : :: . :.: : . :: . ::
XP_005 IEPRLL-----WERV-----EKL--VPRPGSGSSSGS--------------------SN-
580 590 600
780 790 800 810 820 830
pF1KE3 KKIEVQERSPSVPNNQDHAHHVKFSSSVPQRSLLEQAQKPIDIRQRSSQNRQNWLAASES
: : :.. : .:. .: .: :::.
XP_005 --------SGSQPGS-----HPGSQSGSGER-----------FRVRSSS-----------
610 620
840 850 860 870 880 890
pF1KE3 SSEEESPVTGRRSQSSPPYSTIDQKLLVDIHVPDGFK-VGKISPPVYLTNEWVGYNALSE
.:..:: .:.: .. :. : : . :. :: ::..
XP_005 -----------KSEGSP-----SQRLENAVKKPEDKKEVFRPLKPADLT-------ALAK
630 640 650 660
900 910 920 930 940 950
pF1KE3 IFRNDWLTPAPVIQPPEEDGDYVELYDASADTDGDDDDESNDTFEDTYDHANGNDDLDNQ
.: . ..::.. :: ..:.. .: :.:..:. .. :..... . :..
XP_005 ELRA-----VEDVRPPHKVTDY----SSSSEESGTTDEEDDDVEQEGADESTSGPE-DTR
670 680 690 700 710
960 970 980 990 1000 1010
pF1KE3 VDQANDVCKDHDDDNNKFV--DDVNNNYYEAPSCPRASYGRDGS--CKQDGYDGSRGKEE
. .. .. . . .. . .. :::... .:: ..:. .:. : .:....
XP_005 AASSLNLSNGETESVKTMIVHDDVESEPAMTPS-------KEGTLIVRQSTVDQKRASHH
720 730 740 750 760
1020 1030 1040 1050 1060 1070
pF1KE3 AYRGYGSHTANRSHGGSAASEDNAAIGD--QEEHAANIGSERRGSEGDGGKGVVRTSEES
:. :.: : . : :. :... ::
XP_005 ESNGF----AGRIH----------LLPDLLQQSHSSS------------------TS---
770 780 790
1080 1090 1100 1110 1120 1130
pF1KE3 GALGLNGEENCSETDGPGLKRPASQDFEYLQEEPGGGNEASNAIDSGAAPSAPDHESDNK
: ...:. ..:. .. .::...: . . :.:.
XP_005 -----------STSSSPSSSQPTPTMSPQTPQDKLTANETQSA-----SSTLQKHKSS--
800 810 820 830
1140 1150 1160 1170 1180 1190
pF1KE3 DISESSTQSDFSANHSSPSKGSGMSADANFASAILYAGFVEVPEESP-KQPSEVNVNPLY
: . : . :::.:. ... ..:. . :. ...: .. : :::::
XP_005 --SSFTPFIDPRLLQISPSSGTTVTSVVGFSCDGMRP---EAIRQDPTRKGSVVNVNPTN
840 850 860 870 880
1200 1210 1220 1230 1240 1250
pF1KE3 VSPACKKPLIHMYEKEFTSEICCGSLWGVNLLLGTRSNLYLMDRSGKADITKLIRRRPFR
. : : :. :.:.:.::: :..:::::::.::.:.:.:.::::.. . :: :: :.
XP_005 TRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQ
890 900 910 920 930 940
1260 1270 1280 1290 1300 1310
pF1KE3 QIQVLEPLNLLITISGHKNRLRVYHLTWLRNKILNNDPESKRRQEEMLKTEEACKAIDKL
:..::: ::.:.::::.:..::::.:.:::::::.:::: ...: . .. :
XP_005 QMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPEVEKKQ--------GWTTVGDL
950 960 970 980 990 1000
1320 1330 1340 1350 1360 1370
pF1KE3 TGCEHFSVLQHEETTYIAIALKSSIHLYAWAPKSFDESTAIKVCIDQSADSEGDYMSYQA
:: :..:...:. ...::::::...::::::
XP_005 EGCVHYKVVKYERIKFLVIALKSSVEVYAWAPK---------------------------
1010 1020 1030
1380 1390 1400 1410 1420 1430
pF1KE3 YIRILAKIQAADPVNRFKRPDELLHLLKLKVFPTLDHKPVTVDLAIGSEKRLKIFFSSAD
: ..: . .: : : :::. :::.. .:::....:
XP_005 ------------PYHKF---------MAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCA
1040 1050 1060 1070
1440 1450 1460 1470 1480
pF1KE3 GYHLIDAESEVMSDVTLP----KNPLEIII----PQNIIILPDCLGIGMMLTFNAEALSV
:.: .:..: . :. :: ::: .: :. :::::. :. ... .. :.. :
XP_005 GFHAVDVDSGSVYDIYLPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYV
1080 1090 1100 1110 1120 1130
1490 1500 1510 1520 1530 1540
pF1KE3 EANEQLFKKILEMWKDIPSSIAFECTQRTTGWGQKAIEVRSLQSRVLESELKRRSIKKLR
.. .. : .. .: ..:.:.:. ...: :::.::::.::... :.. . .. ..:.
XP_005 NTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLK
1140 1150 1160 1170 1180 1190
1550 1560 1570 1580
pF1KE3 FLCTRGDKLFFTSTLRNHHSRVYFMTLGKLEELQSNYDV
::: :.::.::.:. . :.:::::::.
XP_005 FLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW
1200 1210 1220
>>XP_005264126 (OMIM: 604666) PREDICTED: mitogen-activat (1209 aa)
initn: 2292 init1: 1199 opt: 1295 Z-score: 449.4 bits: 95.6 E(85289): 2.7e-18
Smith-Waterman score: 2027; 31.7% identity (54.2% similar) in 1569 aa overlap (14-1572:14-1203)
10 20 30 40 50 60
pF1KE3 MAGPGGWRDREVTDLGHLPDPTGIFSLDKTIGLGTYGRIYLGLHEKTGAFTAVKVMNARK
::. : ::.::: : ...: ::::..: : : ::: ..:.:::.. .
XP_005 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPG
::::... :.:.:.::: :.::...::::.: ::::
XP_005 ------------------------DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPG
70 80 90
130 140 150 160 170 180
pF1KE3 QRHQLWMVMELCAAGSVTDVVRMTSNQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKG
. :::.:::.:.:::.::.:. :....::::::::: ::::.:::::: :.::::::::
XP_005 HDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKG
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 QNVLLTHNAEVKLVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDV
::::::.::::::::::::::..:: ::::.::::::::::::: :::.: .::::::.
XP_005 QNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 WSVGITAIEMAEGAPPLCNLQPLEALFVILRESAPTVKSSGWSRKFHNFMEKCTIKNFLF
:: :::::::::::::::...:..:::.: :. : .::. ::.:: .:.: : .::..
XP_005 WSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE3 RPTSANMLQHPFVRDIKNERHVVESLTRHLTGIIKKRQKKGIPLIFEREEAIKEQYTVRR
::.. ..:.:::.:: :::.: .: :. . :.:.: :..: : .
XP_005 RPSTEQLLKHPFIRDQPNERQVRIQLKDHID---RTRKKRG-----EKDE------TEYE
280 290 300 310 320
370 380 390 400 410 420
pF1KE3 FRGPSCTHELLRLPTSSRCRPLRVLHGEPSQPRWLPDREEPQVQALQQLQGAARVFMPLQ
. : .: ..: . .::::. .: : .. : :. ::
XP_005 YSGSEEEEE--EVPEQ---------EGEPSSIVNVPG--ESTLR---------RDFLRLQ
330 340 350 360
430 440 450 460 470 480
pF1KE3 ALDSAPKPLKGQAQAPQRLQGAARVFMPLQAQVKAKASKPLQMQIKAPPRLRRAARVLMP
. : ...: .: : . . : . : . : .:. . ::
XP_005 QEN------KERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRR------
370 380 390 400
490 500 510 520 530 540
pF1KE3 LQAQVRAPRLLQVQSQVSKKQQAQTQTSEPQDLDQVPEEFQGQDQVPEQQRQGQAPEQQQ
:. : : : ...:: . : . :. . ::.. . . :..:. : :...
XP_005 LEEQQRRERE-------ARRQQEREQRRREQEEKRRLEELERRRKEEEERRR--AEEEKR
410 420 430 440 450
550 560 570 580 590 600
pF1KE3 RHNQVPEQELEQNQAPEQPEVQEQAAEPAQAETEAEEPESLRVNAQVFLPLLSQDHHVLL
: .. ::: . : :. : . :. . . :. .: .: .::.
XP_005 RVER--EQEYIRRQLEEE-----------QRHLEVLQQQLLQEQA-----MLLHDHRRPH
460 470 480 490 500
610 620 630 640 650 660
pF1KE3 PLHLDTQVLIPVEGQTEGSPQAQAWTLEPPQAIGSVQALIEGLSRDLLRAPNSNNSKPLG
: : .. : ::: . :. ..:: .:
XP_005 PQH------------SQQPP--------PPQ---------QERSKPSFHAP-----EP--
510 520
670 680 690 700 710 720
pF1KE3 PLQTLMENLSSNRFYSQPEQAREKKSKVSTLRQALAKRLSPKRFRAKSSWRPEKLELSDL
. : ..::: .. ::: : . :.
XP_005 -----------KAHYEPADRAREVED----------------RFR--------KTNHSSP
530 540 550
730 740 750 760 770
pF1KE3 EARRQRRQRRWEDIFNQHEEELRQVDKDKEDESSDNDEVFH-SIQ--AEVQIEPLKPYIS
::. .. : : : . .:. :. :.: : ..: :: :. :..
XP_005 EAQSKQTGRVLEP----------PVPSRSESFSNGNSESVHPALQRPAEPQV-PVRTTSR
560 570 580 590
780 790 800 810 820 830
pF1KE3 NPKKIEVQERSPSVPNNQDH--AHHVKFSSSVPQRSLLEQAQKPIDIRQRSSQNRQNWLA
.: . .. :: ..:.. : . . .::. : : :...: . : :... . .
XP_005 SP--VLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVP-RPGSGSSSGSSNS
600 610 620 630 640 650
840 850 860 870 880 890
pF1KE3 ASESSSEEESPV-TGRR---SQSSPPYSTIDQKLLVDIHVPDGFK-VGKISPPVYLTNEW
.:. .:. : .:.: .:: .. .:.: .. :. : : . :. ::
XP_005 GSQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPADLT---
660 670 680 690 700 710
900 910 920 930 940 950
pF1KE3 VGYNALSEIFRNDWLTPAPVIQPPEEDGDYVELYDASADTDGDDDDESNDTFEDTYDHAN
::.. .: . ..::.. :: ..:.. .: :.:
XP_005 ----ALAKELRA-----VEDVRPPHKVTDY----SSSSEESGTTDEE-------------
720 730 740
960 970 980 990 1000 1010
pF1KE3 GNDDLDNQVDQANDVCKDHDDDNNKFVDDVNNNYYEAPSCPRASYGRDGSCKQDGYDGSR
::: .:.: : :
XP_005 -------------------DDD----------------------------VEQEGADEST
750 760
1020 1030 1040 1050 1060 1070
pF1KE3 GKEEAYRGYGSHTANRSHGGSAASEDNAAIGDQEEHAANIGSERRGSEGDGGKGVVRTSE
. : :. .: : :.: . . . . : : . : :.. : .:: ..
XP_005 SGPEDTRAASS--LNLSNGETESVKTMIVHDDVESEPAMTPSKE-------GTLIVRQTQ
770 780 790 800 810
1080 1090 1100 1110 1120 1130
pF1KE3 ESGALGLNGEENCSETDGPGLKRPASQDFEYLQEEPGGGNEASNAIDSGAAPSAPDHESD
... . . . : : : . : . :: :..:. .....
XP_005 SASSTLQKHKSSSSFT--PFI------DPRLLQISPSSGTTVTSVVG-------------
820 830 840 850
1140 1150 1160 1170 1180 1190
pF1KE3 NKDISESSTQSDFSANHSSPSKGSGMSADANFASAILYAGFVEVPEESPKQPSEVNVNPL
:: . :: .: . .. .. : :::::
XP_005 ------------FSCD--------GMRPEA-------------IRQDPTRKGSVVNVNPT
860 870
1200 1210 1220 1230 1240 1250
pF1KE3 YVSPACKKPLIHMYEKEFTSEICCGSLWGVNLLLGTRSNLYLMDRSGKADITKLIRRRPF
. : : :. :.:.:.::: :..:::::::.::.:.:.:.::::.. . :: :: :
XP_005 NTRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRF
880 890 900 910 920 930
1260 1270 1280 1290 1300 1310
pF1KE3 RQIQVLEPLNLLITISGHKNRLRVYHLTWLRNKILNNDPESKRRQEEMLKTEEACKAIDK
.:..::: ::.:.::::.:..::::.:.:::::::.:::: ...: . ..
XP_005 QQMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPEVEKKQ--------GWTTVGD
940 950 960 970 980
1320 1330 1340 1350 1360 1370
pF1KE3 LTGCEHFSVLQHEETTYIAIALKSSIHLYAWAPKSFDESTAIKVCIDQSADSEGDYMSYQ
: :: :..:...:. ...::::::...::::::
XP_005 LEGCVHYKVVKYERIKFLVIALKSSVEVYAWAPK--------------------------
990 1000 1010 1020
1380 1390 1400 1410 1420 1430
pF1KE3 AYIRILAKIQAADPVNRFKRPDELLHLLKLKVFPTLDHKPVTVDLAIGSEKRLKIFFSSA
: ..: . .: : : :::. :::.. .:::....:
XP_005 -------------PYHKF---------MAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSC
1030 1040 1050 1060
1440 1450 1460 1470 1480 1490
pF1KE3 DGYHLIDAESEVMSDVTLPKNPLEIIIPQNIIILPDCLGIGMMLTFNAEALSVEANEQLF
:.: .:..: . :. :: . : :. :::::. :. ... .. :.. :.. ..
XP_005 AGFHAVDVDSGSVYDIYLPTHIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNTYGRIT
1070 1080 1090 1100 1110 1120
1500 1510 1520 1530 1540 1550
pF1KE3 KKILEMWKDIPSSIAFECTQRTTGWGQKAIEVRSLQSRVLESELKRRSIKKLRFLCTRGD
: .. .: ..:.:.:. ...: :::.::::.::... :.. . .. ..:.::: :.:
XP_005 KDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFLCERND
1130 1140 1150 1160 1170 1180
1560 1570 1580
pF1KE3 KLFFTSTLRNHHSRVYFMTLGKLEELQSNYDV
:.::.:. . :.:::::::.
XP_005 KVFFASVRSGGSSQVYFMTLGRTSLLSW
1190 1200
>>XP_005264123 (OMIM: 604666) PREDICTED: mitogen-activat (1229 aa)
initn: 2156 init1: 1199 opt: 1293 Z-score: 448.7 bits: 95.5 E(85289): 3e-18
Smith-Waterman score: 2047; 31.3% identity (55.7% similar) in 1574 aa overlap (14-1572:14-1223)
10 20 30 40 50 60
pF1KE3 MAGPGGWRDREVTDLGHLPDPTGIFSLDKTIGLGTYGRIYLGLHEKTGAFTAVKVMNARK
::. : ::.::: : ...: ::::..: : : ::: ..:.:::.. .
XP_005 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPG
::::... :.:.:.::: :.::...::::.: ::::
XP_005 ------------------------DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPG
70 80 90
130 140 150 160 170 180
pF1KE3 QRHQLWMVMELCAAGSVTDVVRMTSNQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKG
. :::.:::.:.:::.::.:. :....::::::::: ::::.:::::: :.::::::::
XP_005 HDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKG
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 QNVLLTHNAEVKLVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDV
::::::.::::::::::::::..:: ::::.::::::::::::: :::.: .::::::.
XP_005 QNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 WSVGITAIEMAEGAPPLCNLQPLEALFVILRESAPTVKSSGWSRKFHNFMEKCTIKNFLF
:: :::::::::::::::...:..:::.: :. : .::. ::.:: .:.: : .::..
XP_005 WSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE3 RPTSANMLQHPFVRDIKNERHVVESLTRHLTGIIKKRQKKGIPLIFEREEAIKEQYTVRR
::.. ..:.:::.:: :::.: .: :. . :.:.: :..: : .
XP_005 RPSTEQLLKHPFIRDQPNERQVRIQLKDHID---RTRKKRG-----EKDE------TEYE
280 290 300 310 320
370 380 390 400 410 420
pF1KE3 FRGPSCTHELLRLPTSSRCRPLRVLHGEPSQPRWLPDREEPQVQALQQLQGAARVFMPLQ
. : .: ..: . .::::. .: : .. : :. ::
XP_005 YSGSEEEEE--EVPEQ---------EGEPSSIVNVPG--ESTLR---------RDFLRLQ
330 340 350 360
430 440 450 460 470 480
pF1KE3 ALDSAPKPLKGQAQAPQRLQGAARVFMPLQAQVKAKASKPLQMQIKAPPRLRRAARVLMP
. : ...: .: : . . : . : . : .:. . ::
XP_005 QEN------KERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRR------
370 380 390 400
490 500 510 520 530 540
pF1KE3 LQAQVRAPRLLQVQSQVSKKQQAQTQTSEPQDLDQVPEEFQGQDQVPEQQRQGQAPEQQQ
:. : : : ...:: . : . :. . ::.. . . :..:. : :...
XP_005 LEEQQRRERE-------ARRQQEREQRRREQEEKRRLEELERRRKEEEERRR--AEEEKR
410 420 430 440 450
550 560 570 580 590 600
pF1KE3 RHNQVPEQELEQNQAPEQPEVQEQAAEPAQAETEAEEPESLRVNAQVFLPLLSQDHHVLL
: .. ::: . : :. : . :. . . :. .: .: .::.
XP_005 RVER--EQEYIRRQLEEE-----------QRHLEVLQQQLLQEQA-----MLLHDHRRPH
460 470 480 490 500
610 620 630 640 650 660
pF1KE3 PLHLDTQVLIPVEGQTEGSPQAQAWTLEPPQAIGSVQALIEGLSRDLLRAPNSNNSKPLG
: : .. : ::: . :. ..:: .:
XP_005 PQH------------SQQPP--------PPQ---------QERSKPSFHAP-----EP--
510 520
670 680 690 700 710 720
pF1KE3 PLQTLMENLSSNRFYSQPEQAREKKSKVSTLRQALAKRLSPKRFRAKSSWRPEKLELSDL
. : ..::: .... .:..: :: . .... . . . ...
XP_005 -----------KAHYEPADRAREVPVRTTSRSPVLSRRDSPLQGSGQQNSQAGQRNSTSI
530 540 550 560 570
730 740 750 760 770 780
pF1KE3 EARRQRRQRRWEDIFNQHEEELRQVDKDKEDESSDNDEVFHSIQAEVQIEPLKPYISNPK
: : :: . :.: : . :: . ::
XP_005 EPRLL-----WERV-----EKL--VPRPGSGSSSGS--------------------SN--
580 590 600
790 800 810 820 830 840
pF1KE3 KIEVQERSPSVPNNQDHAHHVKFSSSVPQRSLLEQAQKPIDIRQRSSQNRQNWLAASESS
: : :.. : .:. .: .: :::.
XP_005 -------SGSQPGS-----HPGSQSGSGER-----------FRVRSSS------------
610 620
850 860 870 880 890 900
pF1KE3 SEEESPVTGRRSQSSPPYSTIDQKLLVDIHVPDGFKVGKISPPVYLTNEWVGYNALSEIF
.:..:: .:.: .. :. : .. :. ..: : .::.. .
XP_005 ----------KSEGSP-----SQRLENAVKKPEDKK--EVFRPLKPAGE-VDLTALAKEL
630 640 650 660
910 920 930 940 950 960
pF1KE3 RNDWLTPAPVIQPPEEDGDYVELYDASADTDGDDDDESNDTFEDTYDHANGNDDLDNQVD
: . ..::.. :: ..:.. .: :.:..:. .. :..... . :...
XP_005 RA-----VEDVRPPHKVTDY----SSSSEESGTTDEEDDDVEQEGADESTSGPE-DTRAA
670 680 690 700 710
970 980 990 1000 1010
pF1KE3 QANDVCKDHDDDNNKFV--DDVNNNYYEAPSCPRASYGRDGS--CKQDGYDGSRGKEEAY
.. .. . . .. . .. :::... .:: ..:. .:. : .:....
XP_005 SSLNLSNGETESVKTMIVHDDVESEPAMTPS-------KEGTLIVRQSTVDQKRASHHES
720 730 740 750 760 770
1020 1030 1040 1050 1060 1070
pF1KE3 RGYGSHTANRSHGGSAASEDNAAIGD--QEEHAANIGSERRGSEGDGGKGVVRTSEESGA
:. :.: : . : :. :... ::
XP_005 NGF----AGRIH----------LLPDLLQQSHSSS------------------TS-----
780 790
1080 1090 1100 1110 1120 1130
pF1KE3 LGLNGEENCSETDGPGLKRPASQDFEYLQEEPGGGNEASNAIDSGAAPSAPDHESDNKDI
: ...:. ..:. .. .::...: . . :.:.
XP_005 ---------STSSSPSSSQPTPTMSPQTPQDKLTANETQSA-----SSTLQKHKSS----
800 810 820 830
1140 1150 1160 1170 1180 1190
pF1KE3 SESSTQSDFSANHSSPSKGSGMSADANFASAILYAGFVEVPEESP-KQPSEVNVNPLYVS
: . : . :::.:. ... ..:. . :. ...: .. : ::::: .
XP_005 SSFTPFIDPRLLQISPSSGTTVTSVVGFSCDGMRP---EAIRQDPTRKGSVVNVNPTNTR
840 850 860 870 880 890
1200 1210 1220 1230 1240 1250
pF1KE3 PACKKPLIHMYEKEFTSEICCGSLWGVNLLLGTRSNLYLMDRSGKADITKLIRRRPFRQI
: : :. :.:.:.::: :..:::::::.::.:.:.:.::::.. . :: :: :.:.
XP_005 PQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQQM
900 910 920 930 940 950
1260 1270 1280 1290 1300 1310
pF1KE3 QVLEPLNLLITISGHKNRLRVYHLTWLRNKILNNDPESKRRQEEMLKTEEACKAIDKLTG
.::: ::.:.::::.:..::::.:.:::::::.:::: ...: . .. : :
XP_005 DVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPEVEKKQ--------GWTTVGDLEG
960 970 980 990 1000
1320 1330 1340 1350 1360 1370
pF1KE3 CEHFSVLQHEETTYIAIALKSSIHLYAWAPKSFDESTAIKVCIDQSADSEGDYMSYQAYI
: :..:...:. ...::::::...::::::
XP_005 CVHYKVVKYERIKFLVIALKSSVEVYAWAPK-----------------------------
1010 1020 1030
1380 1390 1400 1410 1420 1430
pF1KE3 RILAKIQAADPVNRFKRPDELLHLLKLKVFPTLDHKPVTVDLAIGSEKRLKIFFSSADGY
: ..: . .: : : :::. :::.. .:::....: :.
XP_005 ----------PYHKF---------MAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCAGF
1040 1050 1060 1070
1440 1450 1460 1470 1480
pF1KE3 HLIDAESEVMSDVTLP----KNPLEIII----PQNIIILPDCLGIGMMLTFNAEALSVEA
: .:..: . :. :: ::: .: :. :::::. :. ... .. :.. :..
XP_005 HAVDVDSGSVYDIYLPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYVNT
1080 1090 1100 1110 1120 1130
1490 1500 1510 1520 1530 1540
pF1KE3 NEQLFKKILEMWKDIPSSIAFECTQRTTGWGQKAIEVRSLQSRVLESELKRRSIKKLRFL
.. : .. .: ..:.:.:. ...: :::.::::.::... :.. . .. ..:.::
XP_005 YGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLKFL
1140 1150 1160 1170 1180 1190
1550 1560 1570 1580
pF1KE3 CTRGDKLFFTSTLRNHHSRVYFMTLGKLEELQSNYDV
: :.::.::.:. . :.:::::::.
XP_005 CERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW
1200 1210 1220
>>XP_005264121 (OMIM: 604666) PREDICTED: mitogen-activat (1258 aa)
initn: 2174 init1: 1199 opt: 1293 Z-score: 448.6 bits: 95.5 E(85289): 3e-18
Smith-Waterman score: 2095; 31.7% identity (56.4% similar) in 1576 aa overlap (14-1572:14-1252)
10 20 30 40 50 60
pF1KE3 MAGPGGWRDREVTDLGHLPDPTGIFSLDKTIGLGTYGRIYLGLHEKTGAFTAVKVMNARK
::. : ::.::: : ...: ::::..: : : ::: ..:.:::.. .
XP_005 MANDSPAKSLVDIDLSSLRDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVSFYGAFFKLSPPG
::::... :.:.:.::: :.::...::::.: ::::
XP_005 ------------------------DEEEEIKLEINMLKKYSHHRNIATYYGAFIKKSPPG
70 80 90
130 140 150 160 170 180
pF1KE3 QRHQLWMVMELCAAGSVTDVVRMTSNQSLKEDWIAYICREILQGLAHLHAHRVIHRDIKG
. :::.:::.:.:::.::.:. :....::::::::: ::::.:::::: :.::::::::
XP_005 HDDQLWLVMEFCGAGSITDLVKNTKGNTLKEDWIAYISREILRGLAHLHIHHVIHRDIKG
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 QNVLLTHNAEVKLVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIDCDEDPRRSYDYRSDV
::::::.::::::::::::::..:: ::::.::::::::::::: :::.: .::::::.
XP_005 QNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDATYDYRSDL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 WSVGITAIEMAEGAPPLCNLQPLEALFVILRESAPTVKSSGWSRKFHNFMEKCTIKNFLF
:: :::::::::::::::...:..:::.: :. : .::. ::.:: .:.: : .::..
XP_005 WSCGITAIEMAEGAPPLCDMHPMRALFLIPRNPPPRLKSKKWSKKFFSFIEGCLVKNYMQ
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE3 RPTSANMLQHPFVRDIKNERHVVESLTRHLTGIIKKRQKKGIPLIFEREEAIKEQYTVRR
::.. ..:.:::.:: :::.: .: :. . :.:.: :..: : .
XP_005 RPSTEQLLKHPFIRDQPNERQVRIQLKDHID---RTRKKRG-----EKDE------TEYE
280 290 300 310 320
370 380 390 400 410 420
pF1KE3 FRGPSCTHELLRLPTSSRCRPLRVLHGEPSQPRWLPDREEPQVQALQQLQGAARVFMPLQ
. : .: ..: . .::::. .: : .. : :. ::
XP_005 YSGSEEEEE--EVPEQ---------EGEPSSIVNVPG--ESTLR---------RDFLRLQ
330 340 350 360
430 440 450 460 470 480
pF1KE3 ALDSAPKPLKGQAQAPQRLQGAARVFMPLQAQVKAKASKPLQMQIKAPPRLRRAARVLMP
. : ...: .: : . . : . : . : .:. . ::
XP_005 QEN------KERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRR------
370 380 390 400
490 500 510 520 530 540
pF1KE3 LQAQVRAPRLLQVQSQVSKKQQAQTQTSEPQDLDQVPEEFQGQDQVPEQQRQGQAPEQQQ
:. : : : . :.. .... : . . ..:.. .: . . .. :..:. . ::.
XP_005 LEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVER-EQEY
410 420 430 440 450 460
550 560 570 580 590 600
pF1KE3 RHNQVPEQELEQNQAPEQPEVQEQAAEPAQAETEAEEPESLRVNAQVFLPLLSQDHHVLL
. :. :.: .. .. .: .:::: : . .: : : .:. . :.:.. ::
XP_005 IRRQL-EEEQRHLEVLQQQLLQEQAM---LLECRWREMEEHR-QAERLQRQLQQEQAYLL
470 480 490 500 510 520
610 620 630 640 650 660
pF1KE3 PLHLDTQVLIPVEGQTEGSPQAQAWTLEPPQAIGSVQALIEGLSRDLLRAPNSNNSKPLG
:. : . : ..: .: ::: . :. ..:: .:
XP_005 SLQHDHRRPHPQHSQ---QPP-------PPQ---------QERSKPSFHAP-----EP--
530 540 550
670 680 690 700 710
pF1KE3 PLQTLMENLSSNRFYSQPEQAREKKSKVSTLRQALAKRLSPKRFRAK-SSWRPEKLELSD
. : ..::: .... .:..: :: . .. .: .. :.
XP_005 -----------KAHYEPADRAREVPVRTTSRSPVLSRRDSPLQGSGQQNSQAGQRNSTSS
560 570 580 590 600
720 730 740 750 760 770
pF1KE3 LEARRQRRQRRWEDIFNQHEEELRQVDKDKEDESSDNDEVFHSIQAEVQIEPLKPYISNP
.: : :: . :.: : . :: . ::
XP_005 IEPRLL-----WERV-----EKL--VPRPGSGSSSGS--------------------SN-
610 620 630
780 790 800 810 820 830
pF1KE3 KKIEVQERSPSVPNNQDHAHHVKFSSSVPQRSLLEQAQKPIDIRQRSSQNRQNWLAASES
: : :.. : .:. .: .: :::.
XP_005 --------SGSQPGS-----HPGSQSGSGER-----------FRVRSSS-----------
640 650
840 850 860 870 880 890
pF1KE3 SSEEESPVTGRRSQSSPPYSTIDQKLLVDIHVPDGFK-VGKISPPVYLTNEWVGYNALSE
.:..:: .:.: .. :. : : . :. :: ::..
XP_005 -----------KSEGSP-----SQRLENAVKKPEDKKEVFRPLKPADLT-------ALAK
660 670 680 690
900 910 920 930 940 950
pF1KE3 IFRNDWLTPAPVIQPPEEDGDYVELYDASADTDGDDDDESNDTFEDTYDHANGNDDLDNQ
.: . ..::.. :: ..:.. .: :.:..:. .. :..... . :..
XP_005 ELRA-----VEDVRPPHKVTDY----SSSSEESGTTDEEDDDVEQEGADESTSGPE-DTR
700 710 720 730 740
960 970 980 990 1000 1010
pF1KE3 VDQANDVCKDHDDDNNKFV--DDVNNNYYEAPSCPRASYGRDGS--CKQDGYDGSRGKEE
. .. .. . . .. . .. :::... .:: ..:. .:. : .:....
XP_005 AASSLNLSNGETESVKTMIVHDDVESEPAMTPS-------KEGTLIVRQSTVDQKRASHH
750 760 770 780 790
1020 1030 1040 1050 1060 1070
pF1KE3 AYRGYGSHTANRSHGGSAASEDNAAIGD--QEEHAANIGSERRGSEGDGGKGVVRTSEES
:. :.: : . : :. :... ::
XP_005 ESNGF----AGRIH----------LLPDLLQQSHSSS------------------TS---
800 810 820
1080 1090 1100 1110 1120 1130
pF1KE3 GALGLNGEENCSETDGPGLKRPASQDFEYLQEEPGGGNEASNAIDSGAAPSAPDHESDNK
: ...:. ..:. .. .::...: . . :.:.
XP_005 -----------STSSSPSSSQPTPTMSPQTPQDKLTANETQSA-----SSTLQKHKSS--
830 840 850 860
1140 1150 1160 1170 1180 1190
pF1KE3 DISESSTQSDFSANHSSPSKGSGMSADANFASAILYAGFVEVPEESP-KQPSEVNVNPLY
: . : . :::.:. ... ..:. . :. ...: .. : :::::
XP_005 --SSFTPFIDPRLLQISPSSGTTVTSVVGFSCDGMRP---EAIRQDPTRKGSVVNVNPTN
870 880 890 900 910
1200 1210 1220 1230 1240 1250
pF1KE3 VSPACKKPLIHMYEKEFTSEICCGSLWGVNLLLGTRSNLYLMDRSGKADITKLIRRRPFR
. : : :. :.:.:.::: :..:::::::.::.:.:.:.::::.. . :: :: :.
XP_005 TRPQSDTPEIRKYKKRFNSEILCAALWGVNLLVGTESGLMLLDRSGQGKVYPLINRRRFQ
920 930 940 950 960 970
1260 1270 1280 1290 1300 1310
pF1KE3 QIQVLEPLNLLITISGHKNRLRVYHLTWLRNKILNNDPESKRRQEEMLKTEEACKAIDKL
:..::: ::.:.::::.:..::::.:.:::::::.:::: ...: . .. :
XP_005 QMDVLEGLNVLVTISGKKDKLRVYYLSWLRNKILHNDPEVEKKQ--------GWTTVGDL
980 990 1000 1010 1020 1030
1320 1330 1340 1350 1360 1370
pF1KE3 TGCEHFSVLQHEETTYIAIALKSSIHLYAWAPKSFDESTAIKVCIDQSADSEGDYMSYQA
:: :..:...:. ...::::::...::::::
XP_005 EGCVHYKVVKYERIKFLVIALKSSVEVYAWAPK---------------------------
1040 1050 1060
1380 1390 1400 1410 1420 1430
pF1KE3 YIRILAKIQAADPVNRFKRPDELLHLLKLKVFPTLDHKPVTVDLAIGSEKRLKIFFSSAD
: ..: . .: : : :::. :::.. .:::....:
XP_005 ------------PYHKF---------MAFKSFGELVHKPLLVDLTVEEGQRLKVIYGSCA
1070 1080 1090 1100
1440 1450 1460 1470 1480
pF1KE3 GYHLIDAESEVMSDVTLP----KNPLEIII----PQNIIILPDCLGIGMMLTFNAEALSV
:.: .:..: . :. :: ::: .: :. :::::. :. ... .. :.. :
XP_005 GFHAVDVDSGSVYDIYLPTHVRKNPHSMIQCSIKPHAIIILPNTDGMELLVCYEDEGVYV
1110 1120 1130 1140 1150 1160
1490 1500 1510 1520 1530 1540
pF1KE3 EANEQLFKKILEMWKDIPSSIAFECTQRTTGWGQKAIEVRSLQSRVLESELKRRSIKKLR
.. .. : .. .: ..:.:.:. ...: :::.::::.::... :.. . .. ..:.
XP_005 NTYGRITKDVVLQWGEMPTSVAYIRSNQTMGWGEKAIEIRSVETGHLDGVFMHKRAQRLK
1170 1180 1190 1200 1210 1220
1550 1560 1570 1580
pF1KE3 FLCTRGDKLFFTSTLRNHHSRVYFMTLGKLEELQSNYDV
::: :.::.::.:. . :.:::::::.
XP_005 FLCERNDKVFFASVRSGGSSQVYFMTLGRTSLLSW
1230 1240 1250
1582 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 19:20:28 2016 done: Mon Nov 7 19:20:31 2016
Total Scan time: 13.610 Total Display time: 0.820
Function used was FASTA [36.3.4 Apr, 2011]