Result of FASTA (omim) for
pFN21AE9645
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9645, 2492 aa
1>>>pF1KE9645 2492 - 2492 aa - 2492 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.0757+/-0.000645; mu= -14.7792+/- 0.040
mean_var=612.5189+/-124.711, 0's: 0 Z-trim(118.8): 249 B-trim: 0 in 0/58
Lambda= 0.051822
statistics sampled from 31906 (32156) to 31906 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.377), width: 16
Scan time: 23.930
The best scores are: opt bits E(85289)
NP_000480 (OMIM: 300032,300448,300504,301040,30958 (2492) 16258 1233.2 0
XP_005262210 (OMIM: 300032,300448,300504,301040,30 (2491) 16240 1231.8 0
XP_005262212 (OMIM: 300032,300448,300504,301040,30 (2453) 16014 1214.9 0
XP_016885091 (OMIM: 300032,300448,300504,301040,30 (2452) 15996 1213.6 0
XP_005262213 (OMIM: 300032,300448,300504,301040,30 (2437) 15911 1207.2 0
XP_016885092 (OMIM: 300032,300448,300504,301040,30 (2436) 15893 1205.9 0
NP_612114 (OMIM: 300032,300448,300504,301040,30958 (2454) 15259 1158.5 0
XP_006724730 (OMIM: 300032,300448,300504,301040,30 (2399) 15252 1158.0 0
XP_016885095 (OMIM: 300032,300448,300504,301040,30 (2415) 15252 1158.0 0
XP_006724729 (OMIM: 300032,300448,300504,301040,30 (2453) 15251 1157.9 0
XP_016885097 (OMIM: 300032,300448,300504,301040,30 (2398) 15244 1157.4 0
XP_016885096 (OMIM: 300032,300448,300504,301040,30 (2414) 15244 1157.4 0
XP_016885100 (OMIM: 300032,300448,300504,301040,30 (2370) 12361 941.8 0
XP_016885099 (OMIM: 300032,300448,300504,301040,30 (2385) 12361 941.8 0
XP_016885098 (OMIM: 300032,300448,300504,301040,30 (2386) 12361 941.8 0
XP_016885094 (OMIM: 300032,300448,300504,301040,30 (2424) 12361 941.8 0
XP_005262214 (OMIM: 300032,300448,300504,301040,30 (2424) 12361 941.8 0
XP_016885093 (OMIM: 300032,300448,300504,301040,30 (2425) 12361 941.8 0
XP_016885090 (OMIM: 300032,300448,300504,301040,30 (2462) 12361 941.8 0
XP_005262211 (OMIM: 300032,300448,300504,301040,30 (2463) 12361 941.8 0
XP_006724731 (OMIM: 300032,300448,300504,301040,30 (1871) 12054 918.8 0
NP_000115 (OMIM: 133540,211980,214150,278800,60063 (1493) 395 47.0 0.0022
NP_001333369 (OMIM: 133540,211980,214150,278800,60 (1493) 395 47.0 0.0022
XP_011540602 (OMIM: 114480,603615,605027) PREDICTE ( 489) 370 44.7 0.0036
XP_011540601 (OMIM: 114480,603615,605027) PREDICTE ( 489) 370 44.7 0.0036
XP_006711038 (OMIM: 114480,603615,605027) PREDICTE ( 567) 370 44.8 0.004
NP_003570 (OMIM: 114480,603615,605027) DNA repair ( 747) 370 44.9 0.0049
NP_001136020 (OMIM: 114480,603615,605027) DNA repa ( 747) 370 44.9 0.0049
>>NP_000480 (OMIM: 300032,300448,300504,301040,309580) t (2492 aa)
initn: 16258 init1: 16258 opt: 16258 Z-score: 6588.2 bits: 1233.2 E(85289): 0
Smith-Waterman score: 16258; 100.0% identity (100.0% similar) in 2492 aa overlap (1-2492:1-2492)
10 20 30 40 50 60
pF1KE9 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 LPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE9 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE9 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE9 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE9 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE9 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE9 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE9 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE9 IMELRDRLPKKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IMELRDRLPKKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE9 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE9 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE9 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE9 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE9 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE9 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE9 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE9 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE9 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE9 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE9 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE9 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE9 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE9 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KE9 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KE9 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KE9 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KE9 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KE9 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KE9 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KE9 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KE9 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KE9 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KE9 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KE9 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY
2410 2420 2430 2440 2450 2460
2470 2480 2490
pF1KE9 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
::::::::::::::::::::::::::::::::
NP_000 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
2470 2480 2490
>>XP_005262210 (OMIM: 300032,300448,300504,301040,309580 (2491 aa)
initn: 15230 init1: 15230 opt: 16240 Z-score: 6580.9 bits: 1231.8 E(85289): 0
Smith-Waterman score: 16240; 100.0% identity (100.0% similar) in 2492 aa overlap (1-2492:1-2491)
10 20 30 40 50 60
pF1KE9 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 LPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNH
::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
XP_005 LPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRG-DGLHGIVSCTACGQQVNH
130 140 150 160 170
190 200 210 220 230 240
pF1KE9 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE9 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE9 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE9 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE9 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE9 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE9 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE9 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE9 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE9 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE9 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE9 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE9 IMELRDRLPKKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IMELRDRLPKKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDG
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE9 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE9 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE9 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE9 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KE9 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KE9 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KE9 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420 1430 1440
pF1KE9 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
1380 1390 1400 1410 1420 1430
1450 1460 1470 1480 1490 1500
pF1KE9 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE
1440 1450 1460 1470 1480 1490
1510 1520 1530 1540 1550 1560
pF1KE9 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL
1500 1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KE9 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
1560 1570 1580 1590 1600 1610
1630 1640 1650 1660 1670 1680
pF1KE9 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI
1620 1630 1640 1650 1660 1670
1690 1700 1710 1720 1730 1740
pF1KE9 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS
1680 1690 1700 1710 1720 1730
1750 1760 1770 1780 1790 1800
pF1KE9 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
1740 1750 1760 1770 1780 1790
1810 1820 1830 1840 1850 1860
pF1KE9 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN
1800 1810 1820 1830 1840 1850
1870 1880 1890 1900 1910 1920
pF1KE9 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM
1860 1870 1880 1890 1900 1910
1930 1940 1950 1960 1970 1980
pF1KE9 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
1920 1930 1940 1950 1960 1970
1990 2000 2010 2020 2030 2040
pF1KE9 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF
1980 1990 2000 2010 2020 2030
2050 2060 2070 2080 2090 2100
pF1KE9 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE
2040 2050 2060 2070 2080 2090
2110 2120 2130 2140 2150 2160
pF1KE9 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
2100 2110 2120 2130 2140 2150
2170 2180 2190 2200 2210 2220
pF1KE9 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS
2160 2170 2180 2190 2200 2210
2230 2240 2250 2260 2270 2280
pF1KE9 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA
2220 2230 2240 2250 2260 2270
2290 2300 2310 2320 2330 2340
pF1KE9 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
2280 2290 2300 2310 2320 2330
2350 2360 2370 2380 2390 2400
pF1KE9 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM
2340 2350 2360 2370 2380 2390
2410 2420 2430 2440 2450 2460
pF1KE9 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY
2400 2410 2420 2430 2440 2450
2470 2480 2490
pF1KE9 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
::::::::::::::::::::::::::::::::
XP_005 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
2460 2470 2480 2490
>>XP_005262212 (OMIM: 300032,300448,300504,301040,309580 (2453 aa)
initn: 16014 init1: 16014 opt: 16014 Z-score: 6489.7 bits: 1214.9 E(85289): 0
Smith-Waterman score: 16014; 100.0% identity (100.0% similar) in 2453 aa overlap (40-2492:1-2453)
10 20 30 40 50 60
pF1KE9 KLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSE
::::::::::::::::::::::::::::::
XP_005 MNQNTDKISGSGSNSDMMENSKEEGTSSSE
10 20 30
70 80 90 100 110 120
pF1KE9 KSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE9 PEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRH
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE9 PSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE9 RKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVY
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE9 EHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE9 YVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNT
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE9 KEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKST
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE9 GGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGS
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE9 SGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVP
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE9 QDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTE
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE9 TNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNS
640 650 660 670 680 690
730 740 750 760 770 780
pF1KE9 DSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSD
700 710 720 730 740 750
790 800 810 820 830 840
pF1KE9 FDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDS
760 770 780 790 800 810
850 860 870 880 890 900
pF1KE9 SEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLP
820 830 840 850 860 870
910 920 930 940 950 960
pF1KE9 KKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KE9 KKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFP
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KE9 KGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGR
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KE9 EKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEI
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KE9 QSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIE
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KE9 DDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPEN
1180 1190 1200 1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KE9 RIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSE
1240 1250 1260 1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KE9 ESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGV
1300 1310 1320 1330 1340 1350
1390 1400 1410 1420 1430 1440
pF1KE9 SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK
1360 1370 1380 1390 1400 1410
1450 1460 1470 1480 1490 1500
pF1KE9 EEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAE
1420 1430 1440 1450 1460 1470
1510 1520 1530 1540 1550 1560
pF1KE9 REREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQ
1480 1490 1500 1510 1520 1530
1570 1580 1590 1600 1610 1620
pF1KE9 FMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLN
1540 1550 1560 1570 1580 1590
1630 1640 1650 1660 1670 1680
pF1KE9 TALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNL
1600 1610 1620 1630 1640 1650
1690 1700 1710 1720 1730 1740
pF1KE9 AQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGT
1660 1670 1680 1690 1700 1710
1750 1760 1770 1780 1790 1800
pF1KE9 PLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYE
1720 1730 1740 1750 1760 1770
1810 1820 1830 1840 1850 1860
pF1KE9 MLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAG
1780 1790 1800 1810 1820 1830
1870 1880 1890 1900 1910 1920
pF1KE9 AKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTK
1840 1850 1860 1870 1880 1890
1930 1940 1950 1960 1970 1980
pF1KE9 KKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKAT
1900 1910 1920 1930 1940 1950
1990 2000 2010 2020 2030 2040
pF1KE9 SSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDL
1960 1970 1980 1990 2000 2010
2050 2060 2070 2080 2090 2100
pF1KE9 IEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVR
2020 2030 2040 2050 2060 2070
2110 2120 2130 2140 2150 2160
pF1KE9 GRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQG
2080 2090 2100 2110 2120 2130
2170 2180 2190 2200 2210 2220
pF1KE9 TMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTP
2140 2150 2160 2170 2180 2190
2230 2240 2250 2260 2270 2280
pF1KE9 MLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRF
2200 2210 2220 2230 2240 2250
2290 2300 2310 2320 2330 2340
pF1KE9 NIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQP
2260 2270 2280 2290 2300 2310
2350 2360 2370 2380 2390 2400
pF1KE9 LEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRIL
2320 2330 2340 2350 2360 2370
2410 2420 2430 2440 2450 2460
pF1KE9 MNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQP
2380 2390 2400 2410 2420 2430
2470 2480 2490
pF1KE9 PPLQRAPPPMRSKNPGPSQGKSM
:::::::::::::::::::::::
XP_005 PPLQRAPPPMRSKNPGPSQGKSM
2440 2450
>>XP_016885091 (OMIM: 300032,300448,300504,301040,309580 (2452 aa)
initn: 15230 init1: 15230 opt: 15996 Z-score: 6482.4 bits: 1213.6 E(85289): 0
Smith-Waterman score: 15996; 100.0% identity (100.0% similar) in 2453 aa overlap (40-2492:1-2452)
10 20 30 40 50 60
pF1KE9 KLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSE
::::::::::::::::::::::::::::::
XP_016 MNQNTDKISGSGSNSDMMENSKEEGTSSSE
10 20 30
70 80 90 100 110 120
pF1KE9 KSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE9 PEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRH
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
XP_016 PEPVLNEDKDDFKGPEFRSRSKMKTENLKKRG-DGLHGIVSCTACGQQVNHFQKDSIYRH
100 110 120 130 140
190 200 210 220 230 240
pF1KE9 PSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLG
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE9 RKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVY
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE9 EHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSS
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE9 YVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNT
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE9 KEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKST
390 400 410 420 430 440
490 500 510 520 530 540
pF1KE9 GGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGS
450 460 470 480 490 500
550 560 570 580 590 600
pF1KE9 SGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVP
510 520 530 540 550 560
610 620 630 640 650 660
pF1KE9 QDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTE
570 580 590 600 610 620
670 680 690 700 710 720
pF1KE9 TNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNS
630 640 650 660 670 680
730 740 750 760 770 780
pF1KE9 DSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSD
690 700 710 720 730 740
790 800 810 820 830 840
pF1KE9 FDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDS
750 760 770 780 790 800
850 860 870 880 890 900
pF1KE9 SEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLP
810 820 830 840 850 860
910 920 930 940 950 960
pF1KE9 KKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KE9 KKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFP
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KE9 KGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGR
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KE9 EKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEI
1050 1060 1070 1080 1090 1100
1150 1160 1170 1180 1190 1200
pF1KE9 QSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIE
1110 1120 1130 1140 1150 1160
1210 1220 1230 1240 1250 1260
pF1KE9 DDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPEN
1170 1180 1190 1200 1210 1220
1270 1280 1290 1300 1310 1320
pF1KE9 RIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSE
1230 1240 1250 1260 1270 1280
1330 1340 1350 1360 1370 1380
pF1KE9 ESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGV
1290 1300 1310 1320 1330 1340
1390 1400 1410 1420 1430 1440
pF1KE9 SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK
1350 1360 1370 1380 1390 1400
1450 1460 1470 1480 1490 1500
pF1KE9 EEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAE
1410 1420 1430 1440 1450 1460
1510 1520 1530 1540 1550 1560
pF1KE9 REREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQ
1470 1480 1490 1500 1510 1520
1570 1580 1590 1600 1610 1620
pF1KE9 FMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLN
1530 1540 1550 1560 1570 1580
1630 1640 1650 1660 1670 1680
pF1KE9 TALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNL
1590 1600 1610 1620 1630 1640
1690 1700 1710 1720 1730 1740
pF1KE9 AQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGT
1650 1660 1670 1680 1690 1700
1750 1760 1770 1780 1790 1800
pF1KE9 PLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYE
1710 1720 1730 1740 1750 1760
1810 1820 1830 1840 1850 1860
pF1KE9 MLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAG
1770 1780 1790 1800 1810 1820
1870 1880 1890 1900 1910 1920
pF1KE9 AKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTK
1830 1840 1850 1860 1870 1880
1930 1940 1950 1960 1970 1980
pF1KE9 KKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKAT
1890 1900 1910 1920 1930 1940
1990 2000 2010 2020 2030 2040
pF1KE9 SSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDL
1950 1960 1970 1980 1990 2000
2050 2060 2070 2080 2090 2100
pF1KE9 IEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVR
2010 2020 2030 2040 2050 2060
2110 2120 2130 2140 2150 2160
pF1KE9 GRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQG
2070 2080 2090 2100 2110 2120
2170 2180 2190 2200 2210 2220
pF1KE9 TMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTP
2130 2140 2150 2160 2170 2180
2230 2240 2250 2260 2270 2280
pF1KE9 MLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRF
2190 2200 2210 2220 2230 2240
2290 2300 2310 2320 2330 2340
pF1KE9 NIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQP
2250 2260 2270 2280 2290 2300
2350 2360 2370 2380 2390 2400
pF1KE9 LEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRIL
2310 2320 2330 2340 2350 2360
2410 2420 2430 2440 2450 2460
pF1KE9 MNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQP
2370 2380 2390 2400 2410 2420
2470 2480 2490
pF1KE9 PPLQRAPPPMRSKNPGPSQGKSM
:::::::::::::::::::::::
XP_016 PPLQRAPPPMRSKNPGPSQGKSM
2430 2440 2450
>>XP_005262213 (OMIM: 300032,300448,300504,301040,309580 (2437 aa)
initn: 15911 init1: 15911 opt: 15911 Z-score: 6448.1 bits: 1207.2 E(85289): 0
Smith-Waterman score: 15911; 100.0% identity (100.0% similar) in 2437 aa overlap (56-2492:1-2437)
30 40 50 60 70 80
pF1KE9 SEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSI
::::::::::::::::::::::::::::::
XP_005 MMENSKEEGTSSSEKSKSSGSSRSKRKPSI
10 20 30
90 100 110 120 130 140
pF1KE9 VTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPE
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE9 FRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYM
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE9 SDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYC
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE9 YICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCN
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE9 GEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISS
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE9 ATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARK
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE9 GEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYE
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE9 PANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNI
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE9 SSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLE
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE9 KCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETV
580 590 600 610 620 630
690 700 710 720 730 740
pF1KE9 KEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMS
640 650 660 670 680 690
750 760 770 780 790 800
pF1KE9 HSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISK
700 710 720 730 740 750
810 820 830 840 850 860
pF1KE9 KKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGH
760 770 780 790 800 810
870 880 890 900 910 920
pF1KE9 KNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLS
820 830 840 850 860 870
930 940 950 960 970 980
pF1KE9 GKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS
880 890 900 910 920 930
990 1000 1010 1020 1030 1040
pF1KE9 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK
940 950 960 970 980 990
1050 1060 1070 1080 1090 1100
pF1KE9 SKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQ
1000 1010 1020 1030 1040 1050
1110 1120 1130 1140 1150 1160
pF1KE9 DCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDN
1060 1070 1080 1090 1100 1110
1170 1180 1190 1200 1210 1220
pF1KE9 KKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQK
1120 1130 1140 1150 1160 1170
1230 1240 1250 1260 1270 1280
pF1KE9 IKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLS
1180 1190 1200 1210 1220 1230
1290 1300 1310 1320 1330 1340
pF1KE9 SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL
1240 1250 1260 1270 1280 1290
1350 1360 1370 1380 1390 1400
pF1KE9 TVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTR
1300 1310 1320 1330 1340 1350
1410 1420 1430 1440 1450 1460
pF1KE9 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED
1360 1370 1380 1390 1400 1410
1470 1480 1490 1500 1510 1520
pF1KE9 ENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED
1420 1430 1440 1450 1460 1470
1530 1540 1550 1560 1570 1580
pF1KE9 ASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKS
1480 1490 1500 1510 1520 1530
1590 1600 1610 1620 1630 1640
pF1KE9 PGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGL
1540 1550 1560 1570 1580 1590
1650 1660 1670 1680 1690 1700
pF1KE9 KDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFN
1600 1610 1620 1630 1640 1650
1710 1720 1730 1740 1750 1760
pF1KE9 KALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFI
1660 1670 1680 1690 1700 1710
1770 1780 1790 1800 1810 1820
pF1KE9 KENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTK
1720 1730 1740 1750 1760 1770
1830 1840 1850 1860 1870 1880
pF1KE9 FLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTH
1780 1790 1800 1810 1820 1830
1890 1900 1910 1920 1930 1940
pF1KE9 PWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSG
1840 1850 1860 1870 1880 1890
1950 1960 1970 1980 1990 2000
pF1KE9 SGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDF
1900 1910 1920 1930 1940 1950
2010 2020 2030 2040 2050 2060
pF1KE9 VTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDK
1960 1970 1980 1990 2000 2010
2070 2080 2090 2100 2110 2120
pF1KE9 DKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGIN
2020 2030 2040 2050 2060 2070
2130 2140 2150 2160 2170 2180
pF1KE9 LVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSL
2080 2090 2100 2110 2120 2130
2190 2200 2210 2220 2230 2240
pF1KE9 SFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHK
2140 2150 2160 2170 2180 2190
2250 2260 2270 2280 2290 2300
pF1KE9 EHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQ
2200 2210 2220 2230 2240 2250
2310 2320 2330 2340 2350 2360
pF1KE9 TPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLS
2260 2270 2280 2290 2300 2310
2370 2380 2390 2400 2410 2420
pF1KE9 EAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQ
2320 2330 2340 2350 2360 2370
2430 2440 2450 2460 2470 2480
pF1KE9 MTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPG
2380 2390 2400 2410 2420 2430
2490
pF1KE9 PSQGKSM
:::::::
XP_005 PSQGKSM
>>XP_016885092 (OMIM: 300032,300448,300504,301040,309580 (2436 aa)
initn: 15230 init1: 15230 opt: 15893 Z-score: 6440.9 bits: 1205.9 E(85289): 0
Smith-Waterman score: 15893; 100.0% identity (100.0% similar) in 2437 aa overlap (56-2492:1-2436)
30 40 50 60 70 80
pF1KE9 SEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSI
::::::::::::::::::::::::::::::
XP_016 MMENSKEEGTSSSEKSKSSGSSRSKRKPSI
10 20 30
90 100 110 120 130 140
pF1KE9 VTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPE
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE9 FRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYM
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_016 FRSRSKMKTENLKKRG-DGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYM
100 110 120 130 140
210 220 230 240 250 260
pF1KE9 SDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYC
150 160 170 180 190 200
270 280 290 300 310 320
pF1KE9 YICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCN
210 220 230 240 250 260
330 340 350 360 370 380
pF1KE9 GEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISS
270 280 290 300 310 320
390 400 410 420 430 440
pF1KE9 ATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARK
330 340 350 360 370 380
450 460 470 480 490 500
pF1KE9 GEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYE
390 400 410 420 430 440
510 520 530 540 550 560
pF1KE9 PANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNI
450 460 470 480 490 500
570 580 590 600 610 620
pF1KE9 SSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLE
510 520 530 540 550 560
630 640 650 660 670 680
pF1KE9 KCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETV
570 580 590 600 610 620
690 700 710 720 730 740
pF1KE9 KEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMS
630 640 650 660 670 680
750 760 770 780 790 800
pF1KE9 HSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISK
690 700 710 720 730 740
810 820 830 840 850 860
pF1KE9 KKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGH
750 760 770 780 790 800
870 880 890 900 910 920
pF1KE9 KNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLS
810 820 830 840 850 860
930 940 950 960 970 980
pF1KE9 GKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS
870 880 890 900 910 920
990 1000 1010 1020 1030 1040
pF1KE9 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK
930 940 950 960 970 980
1050 1060 1070 1080 1090 1100
pF1KE9 SKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQ
990 1000 1010 1020 1030 1040
1110 1120 1130 1140 1150 1160
pF1KE9 DCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDN
1050 1060 1070 1080 1090 1100
1170 1180 1190 1200 1210 1220
pF1KE9 KKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQK
1110 1120 1130 1140 1150 1160
1230 1240 1250 1260 1270 1280
pF1KE9 IKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLS
1170 1180 1190 1200 1210 1220
1290 1300 1310 1320 1330 1340
pF1KE9 SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL
1230 1240 1250 1260 1270 1280
1350 1360 1370 1380 1390 1400
pF1KE9 TVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTR
1290 1300 1310 1320 1330 1340
1410 1420 1430 1440 1450 1460
pF1KE9 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED
1350 1360 1370 1380 1390 1400
1470 1480 1490 1500 1510 1520
pF1KE9 ENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED
1410 1420 1430 1440 1450 1460
1530 1540 1550 1560 1570 1580
pF1KE9 ASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKS
1470 1480 1490 1500 1510 1520
1590 1600 1610 1620 1630 1640
pF1KE9 PGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGL
1530 1540 1550 1560 1570 1580
1650 1660 1670 1680 1690 1700
pF1KE9 KDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFN
1590 1600 1610 1620 1630 1640
1710 1720 1730 1740 1750 1760
pF1KE9 KALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFI
1650 1660 1670 1680 1690 1700
1770 1780 1790 1800 1810 1820
pF1KE9 KENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTK
1710 1720 1730 1740 1750 1760
1830 1840 1850 1860 1870 1880
pF1KE9 FLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTH
1770 1780 1790 1800 1810 1820
1890 1900 1910 1920 1930 1940
pF1KE9 PWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSG
1830 1840 1850 1860 1870 1880
1950 1960 1970 1980 1990 2000
pF1KE9 SGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDF
1890 1900 1910 1920 1930 1940
2010 2020 2030 2040 2050 2060
pF1KE9 VTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDK
1950 1960 1970 1980 1990 2000
2070 2080 2090 2100 2110 2120
pF1KE9 DKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGIN
2010 2020 2030 2040 2050 2060
2130 2140 2150 2160 2170 2180
pF1KE9 LVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSL
2070 2080 2090 2100 2110 2120
2190 2200 2210 2220 2230 2240
pF1KE9 SFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHK
2130 2140 2150 2160 2170 2180
2250 2260 2270 2280 2290 2300
pF1KE9 EHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQ
2190 2200 2210 2220 2230 2240
2310 2320 2330 2340 2350 2360
pF1KE9 TPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLS
2250 2260 2270 2280 2290 2300
2370 2380 2390 2400 2410 2420
pF1KE9 EAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQ
2310 2320 2330 2340 2350 2360
2430 2440 2450 2460 2470 2480
pF1KE9 MTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPG
2370 2380 2390 2400 2410 2420
2490
pF1KE9 PSQGKSM
:::::::
XP_016 PSQGKSM
2430
>>NP_612114 (OMIM: 300032,300448,300504,301040,309580) t (2454 aa)
initn: 15991 init1: 15236 opt: 15259 Z-score: 6184.7 bits: 1158.5 E(85289): 0
Smith-Waterman score: 15919; 98.5% identity (98.5% similar) in 2492 aa overlap (1-2492:1-2454)
10 20 30 40 50 60
pF1KE9 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 LPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNH
::: :::::::::::::::::::
NP_612 LPK--------------------------------------EDGLHGIVSCTACGQQVNH
130 140
190 200 210 220 230 240
pF1KE9 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE9 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE9 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE9 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE9 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT
390 400 410 420 430 440
490 500 510 520 530 540
pF1KE9 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
450 460 470 480 490 500
550 560 570 580 590 600
pF1KE9 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI
510 520 530 540 550 560
610 620 630 640 650 660
pF1KE9 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK
570 580 590 600 610 620
670 680 690 700 710 720
pF1KE9 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
630 640 650 660 670 680
730 740 750 760 770 780
pF1KE9 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK
690 700 710 720 730 740
790 800 810 820 830 840
pF1KE9 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR
750 760 770 780 790 800
850 860 870 880 890 900
pF1KE9 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
810 820 830 840 850 860
910 920 930 940 950 960
pF1KE9 IMELRDRLPKKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 IMELRDRLPKKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDG
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KE9 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KE9 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KE9 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL
1050 1060 1070 1080 1090 1100
1150 1160 1170 1180 1190 1200
pF1KE9 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI
1110 1120 1130 1140 1150 1160
1210 1220 1230 1240 1250 1260
pF1KE9 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
1170 1180 1190 1200 1210 1220
1270 1280 1290 1300 1310 1320
pF1KE9 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV
1230 1240 1250 1260 1270 1280
1330 1340 1350 1360 1370 1380
pF1KE9 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE
1290 1300 1310 1320 1330 1340
1390 1400 1410 1420 1430 1440
pF1KE9 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
1350 1360 1370 1380 1390 1400
1450 1460 1470 1480 1490 1500
pF1KE9 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE
1410 1420 1430 1440 1450 1460
1510 1520 1530 1540 1550 1560
pF1KE9 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL
1470 1480 1490 1500 1510 1520
1570 1580 1590 1600 1610 1620
pF1KE9 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
1530 1540 1550 1560 1570 1580
1630 1640 1650 1660 1670 1680
pF1KE9 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI
1590 1600 1610 1620 1630 1640
1690 1700 1710 1720 1730 1740
pF1KE9 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS
1650 1660 1670 1680 1690 1700
1750 1760 1770 1780 1790 1800
pF1KE9 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
1710 1720 1730 1740 1750 1760
1810 1820 1830 1840 1850 1860
pF1KE9 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN
1770 1780 1790 1800 1810 1820
1870 1880 1890 1900 1910 1920
pF1KE9 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM
1830 1840 1850 1860 1870 1880
1930 1940 1950 1960 1970 1980
pF1KE9 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
1890 1900 1910 1920 1930 1940
1990 2000 2010 2020 2030 2040
pF1KE9 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF
1950 1960 1970 1980 1990 2000
2050 2060 2070 2080 2090 2100
pF1KE9 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE
2010 2020 2030 2040 2050 2060
2110 2120 2130 2140 2150 2160
pF1KE9 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
2070 2080 2090 2100 2110 2120
2170 2180 2190 2200 2210 2220
pF1KE9 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS
2130 2140 2150 2160 2170 2180
2230 2240 2250 2260 2270 2280
pF1KE9 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA
2190 2200 2210 2220 2230 2240
2290 2300 2310 2320 2330 2340
pF1KE9 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
2250 2260 2270 2280 2290 2300
2350 2360 2370 2380 2390 2400
pF1KE9 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM
2310 2320 2330 2340 2350 2360
2410 2420 2430 2440 2450 2460
pF1KE9 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY
2370 2380 2390 2400 2410 2420
2470 2480 2490
pF1KE9 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
::::::::::::::::::::::::::::::::
NP_612 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
2430 2440 2450
>>XP_006724730 (OMIM: 300032,300448,300504,301040,309580 (2399 aa)
initn: 15644 init1: 15236 opt: 15252 Z-score: 6182.0 bits: 1158.0 E(85289): 0
Smith-Waterman score: 15572; 98.4% identity (98.4% similar) in 2437 aa overlap (56-2492:1-2399)
30 40 50 60 70 80
pF1KE9 SEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSEKSKSSGSSRSKRKPSI
::::::::::::::::::::::::::::::
XP_006 MMENSKEEGTSSSEKSKSSGSSRSKRKPSI
10 20 30
90 100 110 120 130 140
pF1KE9 VTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQPEPVLNEDKDDFKGPE
::::::::::::::::::::::::::::::::::::::
XP_006 VTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPK----------------------
40 50 60
150 160 170 180 190 200
pF1KE9 FRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYM
::::::::::::::::::::::::::::::::::::::::::::
XP_006 ----------------EDGLHGIVSCTACGQQVNHFQKDSIYRHPSLQVLICKNCFKYYM
70 80 90 100 110
210 220 230 240 250 260
pF1KE9 SDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLGRKELSTIMDENNQWYC
120 130 140 150 160 170
270 280 290 300 310 320
pF1KE9 YICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVYEHTSRFSPKKTSSNCN
180 190 200 210 220 230
330 340 350 360 370 380
pF1KE9 GEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSSYVKFLKQATDNSEISS
240 250 260 270 280 290
390 400 410 420 430 440
pF1KE9 ATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNTKEHKVIDAKFETKARK
300 310 320 330 340 350
450 460 470 480 490 500
pF1KE9 GEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKSTGGEHKKSDRKEEPQYE
360 370 380 390 400 410
510 520 530 540 550 560
pF1KE9 PANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGSSGTEQEVESSSVKLNI
420 430 440 450 460 470
570 580 590 600 610 620
pF1KE9 SSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLE
480 490 500 510 520 530
630 640 650 660 670 680
pF1KE9 KCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETNPVTSNSDEECNETV
540 550 560 570 580 590
690 700 710 720 730 740
pF1KE9 KEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDSDEMLAILKEVSRMS
600 610 620 630 640 650
750 760 770 780 790 800
pF1KE9 HSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISK
660 670 680 690 700 710
810 820 830 840 850 860
pF1KE9 KKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGH
720 730 740 750 760 770
870 880 890 900 910 920
pF1KE9 KNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLS
780 790 800 810 820 830
930 940 950 960 970 980
pF1KE9 GKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQS
840 850 860 870 880 890
990 1000 1010 1020 1030 1040
pF1KE9 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTTDGEKK
900 910 920 930 940 950
1050 1060 1070 1080 1090 1100
pF1KE9 SKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQ
960 970 980 990 1000 1010
1110 1120 1130 1140 1150 1160
pF1KE9 DCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDAEESSEDN
1020 1030 1040 1050 1060 1070
1170 1180 1190 1200 1210 1220
pF1KE9 KKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQK
1080 1090 1100 1110 1120 1130
1230 1240 1250 1260 1270 1280
pF1KE9 IKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLS
1140 1150 1160 1170 1180 1190
1290 1300 1310 1320 1330 1340
pF1KE9 SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKL
1200 1210 1220 1230 1240 1250
1350 1360 1370 1380 1390 1400
pF1KE9 TVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTR
1260 1270 1280 1290 1300 1310
1410 1420 1430 1440 1450 1460
pF1KE9 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEED
1320 1330 1340 1350 1360 1370
1470 1480 1490 1500 1510 1520
pF1KE9 ENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIED
1380 1390 1400 1410 1420 1430
1530 1540 1550 1560 1570 1580
pF1KE9 ASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQFMWDCCCESVKKTKKS
1440 1450 1460 1470 1480 1490
1590 1600 1610 1620 1630 1640
pF1KE9 PGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLNTALNWMNEFEKWQEGL
1500 1510 1520 1530 1540 1550
1650 1660 1670 1680 1690 1700
pF1KE9 KDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNLAQGRNVKSRKLKEIFN
1560 1570 1580 1590 1600 1610
1710 1720 1730 1740 1750 1760
pF1KE9 KALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGTPLQNNLIEYHCMVNFI
1620 1630 1640 1650 1660 1670
1770 1780 1790 1800 1810 1820
pF1KE9 KENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYEMLAGCVQRKDYTALTK
1680 1690 1700 1710 1720 1730
1830 1840 1850 1860 1870 1880
pF1KE9 FLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAGAKLFQDFQMLSRIWTH
1740 1750 1760 1770 1780 1790
1890 1900 1910 1920 1930 1940
pF1KE9 PWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTKKKKKGKKGKKDSSSSG
1800 1810 1820 1830 1840 1850
1950 1960 1970 1980 1990 2000
pF1KE9 SGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKATSSSNPSSPAPDWYKDF
1860 1870 1880 1890 1900 1910
2010 2020 2030 2040 2050 2060
pF1KE9 VTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDLIEDFLELASREKTEDK
1920 1930 1940 1950 1960 1970
2070 2080 2090 2100 2110 2120
pF1KE9 DKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVRGRLFIISTKAGSLGIN
1980 1990 2000 2010 2020 2030
2130 2140 2150 2160 2170 2180
pF1KE9 LVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQGTMEDKIYDRQVTKQSL
2040 2050 2060 2070 2080 2090
2190 2200 2210 2220 2230 2240
pF1KE9 SFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTPMLPKDTILAELLQIHK
2100 2110 2120 2130 2140 2150
2250 2260 2270 2280 2290 2300
pF1KE9 EHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRFNIPTGTNLPPVSFNSQ
2160 2170 2180 2190 2200 2210
2310 2320 2330 2340 2350 2360
pF1KE9 TPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQPLEDIISAVWKENMNLS
2220 2230 2240 2250 2260 2270
2370 2380 2390 2400 2410 2420
pF1KE9 EAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRILMNRRLQQQYNQQQQQQ
2280 2290 2300 2310 2320 2330
2430 2440 2450 2460 2470 2480
pF1KE9 MTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQPPPLQRAPPPMRSKNPG
2340 2350 2360 2370 2380 2390
2490
pF1KE9 PSQGKSM
:::::::
XP_006 PSQGKSM
>>XP_016885095 (OMIM: 300032,300448,300504,301040,309580 (2415 aa)
initn: 15747 init1: 15236 opt: 15252 Z-score: 6181.9 bits: 1158.0 E(85289): 0
Smith-Waterman score: 15675; 98.5% identity (98.5% similar) in 2453 aa overlap (40-2492:1-2415)
10 20 30 40 50 60
pF1KE9 KLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSE
::::::::::::::::::::::::::::::
XP_016 MNQNTDKISGSGSNSDMMENSKEEGTSSSE
10 20 30
70 80 90 100 110 120
pF1KE9 KSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPK------
40 50 60 70 80
130 140 150 160 170 180
pF1KE9 PEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNHFQKDSIYRH
::::::::::::::::::::::::::::
XP_016 --------------------------------EDGLHGIVSCTACGQQVNHFQKDSIYRH
90 100 110
190 200 210 220 230 240
pF1KE9 PSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFCKKCILRNLG
120 130 140 150 160 170
250 260 270 280 290 300
pF1KE9 RKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKVDSEKSNKVY
180 190 200 210 220 230
310 320 330 340 350 360
pF1KE9 EHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLIETTANMNSS
240 250 260 270 280 290
370 380 390 400 410 420
pF1KE9 YVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNKEKNT
300 310 320 330 340 350
430 440 450 460 470 480
pF1KE9 KEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPTEEQRTNKST
360 370 380 390 400 410
490 500 510 520 530 540
pF1KE9 GGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQGDGS
420 430 440 450 460 470
550 560 570 580 590 600
pF1KE9 SGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVP
480 490 500 510 520 530
610 620 630 640 650 660
pF1KE9 QDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTE
540 550 560 570 580 590
670 680 690 700 710 720
pF1KE9 TNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNS
600 610 620 630 640 650
730 740 750 760 770 780
pF1KE9 DSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSD
660 670 680 690 700 710
790 800 810 820 830 840
pF1KE9 FDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDS
720 730 740 750 760 770
850 860 870 880 890 900
pF1KE9 SEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLP
780 790 800 810 820 830
910 920 930 940 950 960
pF1KE9 KKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFL
840 850 860 870 880 890
970 980 990 1000 1010 1020
pF1KE9 KKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFP
900 910 920 930 940 950
1030 1040 1050 1060 1070 1080
pF1KE9 KGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGR
960 970 980 990 1000 1010
1090 1100 1110 1120 1130 1140
pF1KE9 EKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEI
1020 1030 1040 1050 1060 1070
1150 1160 1170 1180 1190 1200
pF1KE9 QSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIE
1080 1090 1100 1110 1120 1130
1210 1220 1230 1240 1250 1260
pF1KE9 DDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPEN
1140 1150 1160 1170 1180 1190
1270 1280 1290 1300 1310 1320
pF1KE9 RIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSE
1200 1210 1220 1230 1240 1250
1330 1340 1350 1360 1370 1380
pF1KE9 ESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGV
1260 1270 1280 1290 1300 1310
1390 1400 1410 1420 1430 1440
pF1KE9 SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEK
1320 1330 1340 1350 1360 1370
1450 1460 1470 1480 1490 1500
pF1KE9 EEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAE
1380 1390 1400 1410 1420 1430
1510 1520 1530 1540 1550 1560
pF1KE9 REREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKLKPHQVDGVQ
1440 1450 1460 1470 1480 1490
1570 1580 1590 1600 1610 1620
pF1KE9 FMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFSTALVVCPLN
1500 1510 1520 1530 1540 1550
1630 1640 1650 1660 1670 1680
pF1KE9 TALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMIIGYEMYRNL
1560 1570 1580 1590 1600 1610
1690 1700 1710 1720 1730 1740
pF1KE9 AQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRSRRRIILTGT
1620 1630 1640 1650 1660 1670
1750 1760 1770 1780 1790 1800
pF1KE9 PLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVMKKRAHILYE
1680 1690 1700 1710 1720 1730
1810 1820 1830 1840 1850 1860
pF1KE9 MLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNNSEGGRGKAG
1740 1750 1760 1770 1780 1790
1870 1880 1890 1900 1910 1920
pF1KE9 AKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSMSLSSDDYTK
1800 1810 1820 1830 1840 1850
1930 1940 1950 1960 1970 1980
pF1KE9 KKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVSLKLEESKAT
1860 1870 1880 1890 1900 1910
1990 2000 2010 2020 2030 2040
pF1KE9 SSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVFSQSLISLDL
1920 1930 1940 1950 1960 1970
2050 2060 2070 2080 2090 2100
pF1KE9 IEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAEEFNDETNVR
1980 1990 2000 2010 2020 2030
2110 2120 2130 2140 2150 2160
pF1KE9 GRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPVYVYRFLAQG
2040 2050 2060 2070 2080 2090
2170 2180 2190 2200 2210 2220
pF1KE9 TMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNSEKKKKRDTP
2100 2110 2120 2130 2140 2150
2230 2240 2250 2260 2270 2280
pF1KE9 MLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEAEKKGLTMRF
2160 2170 2180 2190 2200 2210
2290 2300 2310 2320 2330 2340
pF1KE9 NIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATNSVTAVRIQP
2220 2230 2240 2250 2260 2270
2350 2360 2370 2380 2390 2400
pF1KE9 LEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQMLISCVQRIL
2280 2290 2300 2310 2320 2330
2410 2420 2430 2440 2450 2460
pF1KE9 MNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMYQPVAGGMQP
2340 2350 2360 2370 2380 2390
2470 2480 2490
pF1KE9 PPLQRAPPPMRSKNPGPSQGKSM
:::::::::::::::::::::::
XP_016 PPLQRAPPPMRSKNPGPSQGKSM
2400 2410
>>XP_006724729 (OMIM: 300032,300448,300504,301040,309580 (2453 aa)
initn: 15231 init1: 15231 opt: 15251 Z-score: 6181.4 bits: 1157.9 E(85289): 0
Smith-Waterman score: 15911; 98.4% identity (98.4% similar) in 2492 aa overlap (1-2492:1-2453)
10 20 30 40 50 60
pF1KE9 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MTAEPMSESKLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KEEGTSSSEKSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 LPKGTVIVQPEPVLNEDKDDFKGPEFRSRSKMKTENLKKRGEDGLHGIVSCTACGQQVNH
::: ::::::::::::::::::
XP_006 LPK---------------------------------------DGLHGIVSCTACGQQVNH
130 140
190 200 210 220 230 240
pF1KE9 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FQKDSIYRHPSLQVLICKNCFKYYMSDDISRDSDGMDEQCRWCAEGGNLICCDFCHNAFC
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE9 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKCILRNLGRKELSTIMDENNQWYCYICHPEPLLDLVTACNSVFENLEQLLQQNKKKIKV
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE9 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSEKSNKVYEHTSRFSPKKTSSNCNGEEKKLDDSCSGSVTYSYSALIVPKEMIKKAKKLI
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE9 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ETTANMNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAM
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE9 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DAVNKEKNTKEHKVIDAKFETKARKGEKPCALEKKDISKSEAKLSRKQVDSEHMHQNVPT
390 400 410 420 430 440
490 500 510 520 530 540
pF1KE9 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEQRTNKSTGGEHKKSDRKEEPQYEPANTSEDLDMDIVSVPSSVPEDIFENLETAMEVQS
450 460 470 480 490 500
550 560 570 580 590 600
pF1KE9 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVDHQGDGSSGTEQEVESSSVKLNISSKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPI
510 520 530 540 550 560
610 620 630 640 650 660
pF1KE9 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KGADCQEVPQDKDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVK
570 580 590 600 610 620
670 680 690 700 710 720
pF1KE9 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TTPLRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSK
630 640 650 660 670 680
730 740 750 760 770 780
pF1KE9 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRK
690 700 710 720 730 740
790 800 810 820 830 840
pF1KE9 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKR
750 760 770 780 790 800
850 860 870 880 890 900
pF1KE9 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTT
810 820 830 840 850 860
910 920 930 940 950 960
pF1KE9 IMELRDRLPKKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IMELRDRLPKKQQASASTDGVDKLSGKEESFTSLEVRKVAETKEKSKHLKTKTCKKVQDG
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KE9 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLP
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KE9 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDK
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KE9 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNL
1050 1060 1070 1080 1090 1100
1150 1160 1170 1180 1190 1200
pF1KE9 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI
1110 1120 1130 1140 1150 1160
1210 1220 1230 1240 1250 1260
pF1KE9 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD
1170 1180 1190 1200 1210 1220
1270 1280 1290 1300 1310 1320
pF1KE9 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV
1230 1240 1250 1260 1270 1280
1330 1340 1350 1360 1370 1380
pF1KE9 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE
1290 1300 1310 1320 1330 1340
1390 1400 1410 1420 1430 1440
pF1KE9 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKS
1350 1360 1370 1380 1390 1400
1450 1460 1470 1480 1490 1500
pF1KE9 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEE
1410 1420 1430 1440 1450 1460
1510 1520 1530 1540 1550 1560
pF1KE9 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHRNMVIKL
1470 1480 1490 1500 1510 1520
1570 1580 1590 1600 1610 1620
pF1KE9 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KPHQVDGVQFMWDCCCESVKKTKKSPGSGCILAHCMGLGKTLQVVSFLHTVLLCDKLDFS
1530 1540 1550 1560 1570 1580
1630 1640 1650 1660 1670 1680
pF1KE9 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TALVVCPLNTALNWMNEFEKWQEGLKDDEKLEVSELATVKRPQERSYMLQRWQEDGGVMI
1590 1600 1610 1620 1630 1640
1690 1700 1710 1720 1730 1740
pF1KE9 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IGYEMYRNLAQGRNVKSRKLKEIFNKALVDPGPDFVVCDEGHILKNEASAVSKAMNSIRS
1650 1660 1670 1680 1690 1700
1750 1760 1770 1780 1790 1800
pF1KE9 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RRRIILTGTPLQNNLIEYHCMVNFIKENLLGSIKEFRNRFINPIQNGQCADSTMVDVRVM
1710 1720 1730 1740 1750 1760
1810 1820 1830 1840 1850 1860
pF1KE9 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKRAHILYEMLAGCVQRKDYTALTKFLPPKHEYVLAVRMTSIQCKLYQYYLDHLTGVGNN
1770 1780 1790 1800 1810 1820
1870 1880 1890 1900 1910 1920
pF1KE9 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEGGRGKAGAKLFQDFQMLSRIWTHPWCLQLDYISKENKGYFDEDSMDEFIASDSDETSM
1830 1840 1850 1860 1870 1880
1930 1940 1950 1960 1970 1980
pF1KE9 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLSSDDYTKKKKKGKKGKKDSSSSGSGSDNDVEVIKVWNSRSRGGGEGNVDETGNNPSVS
1890 1900 1910 1920 1930 1940
1990 2000 2010 2020 2030 2040
pF1KE9 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKLEESKATSSSNPSSPAPDWYKDFVTDADAEVLEHSGKMVLLFEILRMAEEIGDKVLVF
1950 1960 1970 1980 1990 2000
2050 2060 2070 2080 2090 2100
pF1KE9 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQSLISLDLIEDFLELASREKTEDKDKPLIYKGEGKWLRNIDYYRLDGSTTAQSRKKWAE
2010 2020 2030 2040 2050 2060
2110 2120 2130 2140 2150 2160
pF1KE9 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EFNDETNVRGRLFIISTKAGSLGINLVAANRVIIFDASWNPSYDIQSIFRVYRFGQTKPV
2070 2080 2090 2100 2110 2120
2170 2180 2190 2200 2210 2220
pF1KE9 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YVYRFLAQGTMEDKIYDRQVTKQSLSFRVVDQQQVERHFTMNELTELYTFEPDLLDDPNS
2130 2140 2150 2160 2170 2180
2230 2240 2250 2260 2270 2280
pF1KE9 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKKKKRDTPMLPKDTILAELLQIHKEHIVGYHEHDSLLDHKEEEELTEEERKAAWAEYEA
2190 2200 2210 2220 2230 2240
2290 2300 2310 2320 2330 2340
pF1KE9 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EKKGLTMRFNIPTGTNLPPVSFNSQTPYIPFNLGALSAMSNQQLEDLINQGREKVVEATN
2250 2260 2270 2280 2290 2300
2350 2360 2370 2380 2390 2400
pF1KE9 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVTAVRIQPLEDIISAVWKENMNLSEAQVQALALSRQASQELDVKRREAIYNDVLTKQQM
2310 2320 2330 2340 2350 2360
2410 2420 2430 2440 2450 2460
pF1KE9 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LISCVQRILMNRRLQQQYNQQQQQQMTYQQATLGHLMMPKPPNLIMNPSNYQQIDMRGMY
2370 2380 2390 2400 2410 2420
2470 2480 2490
pF1KE9 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
::::::::::::::::::::::::::::::::
XP_006 QPVAGGMQPPPLQRAPPPMRSKNPGPSQGKSM
2430 2440 2450
2492 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 19:11:03 2016 done: Sat Nov 5 19:11:07 2016
Total Scan time: 23.930 Total Display time: 2.500
Function used was FASTA [36.3.4 Apr, 2011]