Result of FASTA (omim) for
pFN21AE2388
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2388, 1484 aa
1>>>pF1KE2388 1484 - 1484 aa - 1484 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.2044+/-0.000462; mu= -18.6525+/- 0.029
mean_var=544.1964+/-112.369, 0's: 0 Z-trim(123.6): 205 B-trim: 0 in 0/59
Lambda= 0.054979
statistics sampled from 43396 (43653) to 43396 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.792), E-opt: 0.2 (0.512), width: 16
Scan time: 22.150
The best scores are: opt bits E(85289)
NP_001276976 (OMIM: 607576) cat eye syndrome criti (1464) 7862 639.7 5e-182
XP_011544430 (OMIM: 607576) PREDICTED: cat eye syn (1436) 7856 639.2 6.8e-182
NP_001276975 (OMIM: 607576) cat eye syndrome criti (1300) 7845 638.3 1.1e-181
XP_016884274 (OMIM: 607576) PREDICTED: cat eye syn (1463) 7845 638.4 1.3e-181
XP_006724142 (OMIM: 607576) PREDICTED: cat eye syn ( 962) 6937 566.2 4.4e-160
XP_011544431 (OMIM: 607576) PREDICTED: cat eye syn (1436) 6082 498.5 1.5e-139
XP_011544434 (OMIM: 607576) PREDICTED: cat eye syn (1409) 3844 321.0 4.2e-86
XP_011515189 (OMIM: 610026) PREDICTED: collagen al (1264) 385 46.6 0.0015
XP_016868641 (OMIM: 610026) PREDICTED: collagen al (1264) 385 46.6 0.0015
XP_011515190 (OMIM: 610026) PREDICTED: collagen al (1195) 384 46.5 0.0015
XP_016868639 (OMIM: 610026) PREDICTED: collagen al (1564) 385 46.7 0.0018
XP_011515188 (OMIM: 610026) PREDICTED: collagen al (1577) 385 46.7 0.0018
XP_011515185 (OMIM: 610026) PREDICTED: collagen al (1606) 385 46.7 0.0018
XP_011536691 (OMIM: 601234) PREDICTED: nascent pol (2078) 386 46.8 0.0021
XP_006719477 (OMIM: 601234) PREDICTED: nascent pol (2082) 386 46.8 0.0021
XP_006719476 (OMIM: 601234) PREDICTED: nascent pol (2082) 386 46.8 0.0021
XP_006719475 (OMIM: 601234) PREDICTED: nascent pol (2082) 386 46.8 0.0021
XP_016855827 (OMIM: 120326) PREDICTED: collagen al (1593) 378 46.1 0.0026
XP_011508858 (OMIM: 104200,120070,141200,203780) P (1257) 374 45.7 0.0027
XP_011515186 (OMIM: 610026) PREDICTED: collagen al (1593) 377 46.0 0.0028
XP_016855830 (OMIM: 120326) PREDICTED: collagen al (1028) 368 45.2 0.0032
XP_011508857 (OMIM: 104200,120070,141200,203780) P (1609) 374 45.8 0.0033
XP_016855829 (OMIM: 120326) PREDICTED: collagen al (1077) 368 45.2 0.0034
XP_011539030 (OMIM: 120326) PREDICTED: collagen al (1089) 368 45.2 0.0034
NP_000082 (OMIM: 104200,120070,141200,203780) coll (1670) 374 45.8 0.0034
XP_011539029 (OMIM: 120326) PREDICTED: collagen al (1302) 368 45.3 0.0039
XP_011539026 (OMIM: 120326) PREDICTED: collagen al (1563) 368 45.3 0.0045
NP_490597 (OMIM: 608749) bromodomain-containing pr (1362) 366 45.1 0.0045
XP_011526156 (OMIM: 608749) PREDICTED: bromodomain (1362) 366 45.1 0.0045
XP_016855828 (OMIM: 120326) PREDICTED: collagen al (1592) 368 45.3 0.0045
NP_001847 (OMIM: 120326) collagen alpha-1(XVI) cha (1604) 368 45.3 0.0046
XP_006712308 (OMIM: 104200,120070,141200,203780) P (1189) 350 43.8 0.0097
>>NP_001276976 (OMIM: 607576) cat eye syndrome critical (1464 aa)
initn: 10329 init1: 7843 opt: 7862 Z-score: 3389.0 bits: 639.7 E(85289): 5e-182
Smith-Waterman score: 10293; 98.7% identity (98.7% similar) in 1484 aa overlap (1-1484:1-1464)
10 20 30 40 50 60
pF1KE2 MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGKSNGELSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGKSNGELSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SRESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDP
::::::::: :::::::::::::::::::::::::::::::
NP_001 LEEKVKAVE--------------------DRAKRRKLREERAWLLAQGKELPPELSHLDP
370 380 390 400
430 440 450 460 470 480
pF1KE2 NSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMD
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE2 ISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFP
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE2 GEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPT
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE2 RRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLR
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE2 GSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLS
650 660 670 680 690 700
730 740 750 760 770 780
pF1KE2 NMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMY
710 720 730 740 750 760
790 800 810 820 830 840
pF1KE2 RSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPP
770 780 790 800 810 820
850 860 870 880 890 900
pF1KE2 NQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMM
830 840 850 860 870 880
910 920 930 940 950 960
pF1KE2 DSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRA
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KE2 PENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERET
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KE2 VGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGE
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120 1130 1140
pF1KE2 ASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLY
1070 1080 1090 1100 1110 1120
1150 1160 1170 1180 1190 1200
pF1KE2 MPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQ
1130 1140 1150 1160 1170 1180
1210 1220 1230 1240 1250 1260
pF1KE2 GMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDK
1190 1200 1210 1220 1230 1240
1270 1280 1290 1300 1310 1320
pF1KE2 NAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLD
1250 1260 1270 1280 1290 1300
1330 1340 1350 1360 1370 1380
pF1KE2 NHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQP
1310 1320 1330 1340 1350 1360
1390 1400 1410 1420 1430 1440
pF1KE2 RAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQE
1370 1380 1390 1400 1410 1420
1450 1460 1470 1480
pF1KE2 MYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPPTLPLDQS
::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPPTLPLDQS
1430 1440 1450 1460
>>XP_011544430 (OMIM: 607576) PREDICTED: cat eye syndrom (1436 aa)
initn: 9824 init1: 7843 opt: 7856 Z-score: 3386.6 bits: 639.2 E(85289): 6.8e-182
Smith-Waterman score: 10028; 96.8% identity (96.8% similar) in 1484 aa overlap (1-1484:1-1436)
10 20 30 40 50 60
pF1KE2 MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGKSNGELSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGKSNGELSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SRESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAE
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQK----------
250 260 270 280 290
310 320 330 340 350 360
pF1KE2 LHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRE
::::::::::::::::::::::::::::::::::::::::::
XP_011 ------------------ETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRE
300 310 320 330
370 380 390 400 410 420
pF1KE2 LEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDP
::::::::: :::::::::::::::::::::::::::::::
XP_011 LEEKVKAVE--------------------DRAKRRKLREERAWLLAQGKELPPELSHLDP
340 350 360 370
430 440 450 460 470 480
pF1KE2 NSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMD
380 390 400 410 420 430
490 500 510 520 530 540
pF1KE2 ISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFP
440 450 460 470 480 490
550 560 570 580 590 600
pF1KE2 GEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPT
500 510 520 530 540 550
610 620 630 640 650 660
pF1KE2 RRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLR
560 570 580 590 600 610
670 680 690 700 710 720
pF1KE2 GSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLS
620 630 640 650 660 670
730 740 750 760 770 780
pF1KE2 NMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMY
680 690 700 710 720 730
790 800 810 820 830 840
pF1KE2 RSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPP
740 750 760 770 780 790
850 860 870 880 890 900
pF1KE2 NQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMM
800 810 820 830 840 850
910 920 930 940 950 960
pF1KE2 DSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRA
860 870 880 890 900 910
970 980 990 1000 1010 1020
pF1KE2 PENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERET
920 930 940 950 960 970
1030 1040 1050 1060 1070 1080
pF1KE2 VGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGE
980 990 1000 1010 1020 1030
1090 1100 1110 1120 1130 1140
pF1KE2 ASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLY
1040 1050 1060 1070 1080 1090
1150 1160 1170 1180 1190 1200
pF1KE2 MPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQ
1100 1110 1120 1130 1140 1150
1210 1220 1230 1240 1250 1260
pF1KE2 GMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDK
1160 1170 1180 1190 1200 1210
1270 1280 1290 1300 1310 1320
pF1KE2 NAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLD
1220 1230 1240 1250 1260 1270
1330 1340 1350 1360 1370 1380
pF1KE2 NHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQP
1280 1290 1300 1310 1320 1330
1390 1400 1410 1420 1430 1440
pF1KE2 RAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQE
1340 1350 1360 1370 1380 1390
1450 1460 1470 1480
pF1KE2 MYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPPTLPLDQS
::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPPTLPLDQS
1400 1410 1420 1430
>>NP_001276975 (OMIM: 607576) cat eye syndrome critical (1300 aa)
initn: 5541 init1: 4196 opt: 7845 Z-score: 3382.5 bits: 638.3 E(85289): 1.1e-181
Smith-Waterman score: 9135; 98.4% identity (98.4% similar) in 1321 aa overlap (164-1484:1-1300)
140 150 160 170 180 190
pF1KE2 LKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGKSNGELSLSRESEGQKNVSSI
::::::::::::::::::::::::::::::
NP_001 MYKEDPVQGKSNGELSLSRESEGQKNVSSI
10 20 30
200 210 220 230 240 250
pF1KE2 PGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQGTWWLLCQTEEEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQGTWWLLCQTEEEW
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE2 RQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAELHPRWMSDHLSIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAELHPRWMSDHLSIK
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE2 PVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRELEEKVKAVEGMCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRELEEKVKAVE----
160 170 180 190 200
380 390 400 410 420 430
pF1KE2 VRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDPNSPMREEKKTKDL
::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----------------DRAKRRKLREERAWLLAQGKELPPELSHLDPNSPMREEKKTKDL
210 220 230 240 250
440 450 460 470 480 490
pF1KE2 FELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLY
260 270 280 290 300 310
500 510 520 530 540 550
pF1KE2 CTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFPGEDGDTDEEFWIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFPGEDGDTDEEFWIR
320 330 340 350 360 370
560 570 580 590 600 610
pF1KE2 EDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPTRRAPSSGDDQSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPTRRAPSSGDDQSSS
380 390 400 410 420 430
620 630 640 650 660 670
pF1KE2 STQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLRGSDPATLYGSSGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLRGSDPATLYGSSGV
440 450 460 470 480 490
680 690 700 710 720 730
pF1KE2 PEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLSNMGPHPGSLQLGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLSNMGPHPGSLQLGQ
500 510 520 530 540 550
740 750 760 770 780 790
pF1KE2 ISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHSAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHSAV
560 570 580 590 600 610
800 810 820 830 840 850
pF1KE2 WNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHG
620 630 640 650 660 670
860 870 880 890 900 910
pF1KE2 VPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQLSS
680 690 700 710 720 730
920 930 940 950 960 970
pF1KE2 RVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPENDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPENDQ
740 750 760 770 780 790
980 990 1000 1010 1020 1030
pF1KE2 AEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVGPELKSSSSESA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -EPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVGPELKSSSSESA
800 810 820 830 840
1040 1050 1060 1070 1080 1090
pF1KE2 DNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGEASPCGSEGKGLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGEASPCGSEGKGLGS
850 860 870 880 890 900
1100 1110 1120 1130 1140 1150
pF1KE2 SGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLYMPGLEYPNSAAHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLYMPGLEYPNSAAHY
910 920 930 940 950 960
1160 1170 1180 1190 1200 1210
pF1KE2 HISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQGMRYSYHPPPQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQGMRYSYHPPPQPS
970 980 990 1000 1010 1020
1220 1230 1240 1250 1260 1270
pF1KE2 YHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDKNAMASLQGCETLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDKNAMASLQGCETLN
1030 1040 1050 1060 1070 1080
1280 1290 1300 1310 1320 1330
pF1KE2 AALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLDNHNAATKRQSSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLDNHNAATKRQSSLS
1090 1100 1110 1120 1130 1140
1340 1350 1360 1370 1380 1390
pF1KE2 ASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQPRAYSSPVAALPPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQPRAYSSPVAALPPH
1150 1160 1170 1180 1190 1200
1400 1410 1420 1430 1440 1450
pF1KE2 HPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQEMYRPSGMQMHPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQEMYRPSGMQMHPVQ
1210 1220 1230 1240 1250 1260
1460 1470 1480
pF1KE2 SQASFPKTPTAATSQEEVPPHKPPTLPLDQS
:::::::::::::::::::::::::::::::
NP_001 SQASFPKTPTAATSQEEVPPHKPPTLPLDQS
1270 1280 1290 1300
>>XP_016884274 (OMIM: 607576) PREDICTED: cat eye syndrom (1463 aa)
initn: 6682 init1: 4196 opt: 7845 Z-score: 3381.7 bits: 638.4 E(85289): 1.3e-181
Smith-Waterman score: 10276; 98.6% identity (98.6% similar) in 1484 aa overlap (1-1484:1-1463)
10 20 30 40 50 60
pF1KE2 MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGKSNGELSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGKSNGELSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SRESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDP
::::::::: :::::::::::::::::::::::::::::::
XP_016 LEEKVKAVE--------------------DRAKRRKLREERAWLLAQGKELPPELSHLDP
370 380 390 400
430 440 450 460 470 480
pF1KE2 NSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMD
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE2 ISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFP
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE2 GEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPT
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE2 RRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLR
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE2 GSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLS
650 660 670 680 690 700
730 740 750 760 770 780
pF1KE2 NMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMY
710 720 730 740 750 760
790 800 810 820 830 840
pF1KE2 RSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPP
770 780 790 800 810 820
850 860 870 880 890 900
pF1KE2 NQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMM
830 840 850 860 870 880
910 920 930 940 950 960
pF1KE2 DSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRA
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KE2 PENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERET
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PENSEAQEPENDQ-EPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERET
950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KE2 VGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGE
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KE2 ASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLY
1060 1070 1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KE2 MPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQ
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KE2 GMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDK
1180 1190 1200 1210 1220 1230
1270 1280 1290 1300 1310 1320
pF1KE2 NAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLD
1240 1250 1260 1270 1280 1290
1330 1340 1350 1360 1370 1380
pF1KE2 NHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQP
1300 1310 1320 1330 1340 1350
1390 1400 1410 1420 1430 1440
pF1KE2 RAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQE
1360 1370 1380 1390 1400 1410
1450 1460 1470 1480
pF1KE2 MYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPPTLPLDQS
::::::::::::::::::::::::::::::::::::::::::::
XP_016 MYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPPTLPLDQS
1420 1430 1440 1450 1460
>>XP_006724142 (OMIM: 607576) PREDICTED: cat eye syndrom (962 aa)
initn: 6937 init1: 6937 opt: 6937 Z-score: 2995.1 bits: 566.2 E(85289): 4.4e-160
Smith-Waterman score: 6937; 100.0% identity (100.0% similar) in 962 aa overlap (523-1484:1-962)
500 510 520 530 540 550
pF1KE2 YCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFPGEDGDTDEEFWI
::::::::::::::::::::::::::::::
XP_006 MSDNLERCFHRAMMKHFPGEDGDTDEEFWI
10 20 30
560 570 580 590 600 610
pF1KE2 REDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPTRRAPSSGDDQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 REDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPTRRAPSSGDDQSS
40 50 60 70 80 90
620 630 640 650 660 670
pF1KE2 SSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLRGSDPATLYGSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLRGSDPATLYGSSG
100 110 120 130 140 150
680 690 700 710 720 730
pF1KE2 VPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLSNMGPHPGSLQLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLSNMGPHPGSLQLG
160 170 180 190 200 210
740 750 760 770 780 790
pF1KE2 QISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHSA
220 230 240 250 260 270
800 810 820 830 840 850
pF1KE2 VWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPH
280 290 300 310 320 330
860 870 880 890 900 910
pF1KE2 GVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQLS
340 350 360 370 380 390
920 930 940 950 960 970
pF1KE2 SRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPEND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPEND
400 410 420 430 440 450
980 990 1000 1010 1020 1030
pF1KE2 QAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVGPELKSSSSES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVGPELKSSSSES
460 470 480 490 500 510
1040 1050 1060 1070 1080 1090
pF1KE2 ADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGEASPCGSEGKGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGEASPCGSEGKGLG
520 530 540 550 560 570
1100 1110 1120 1130 1140 1150
pF1KE2 SSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLYMPGLEYPNSAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLYMPGLEYPNSAAH
580 590 600 610 620 630
1160 1170 1180 1190 1200 1210
pF1KE2 YHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQGMRYSYHPPPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQGMRYSYHPPPQP
640 650 660 670 680 690
1220 1230 1240 1250 1260 1270
pF1KE2 SYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDKNAMASLQGCETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDKNAMASLQGCETL
700 710 720 730 740 750
1280 1290 1300 1310 1320 1330
pF1KE2 NAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLDNHNAATKRQSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLDNHNAATKRQSSL
760 770 780 790 800 810
1340 1350 1360 1370 1380 1390
pF1KE2 SASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQPRAYSSPVAALPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQPRAYSSPVAALPP
820 830 840 850 860 870
1400 1410 1420 1430 1440 1450
pF1KE2 HHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQEMYRPSGMQMHPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQEMYRPSGMQMHPV
880 890 900 910 920 930
1460 1470 1480
pF1KE2 QSQASFPKTPTAATSQEEVPPHKPPTLPLDQS
::::::::::::::::::::::::::::::::
XP_006 QSQASFPKTPTAATSQEEVPPHKPPTLPLDQS
940 950 960
>>XP_011544431 (OMIM: 607576) PREDICTED: cat eye syndrom (1436 aa)
initn: 8529 init1: 6043 opt: 6082 Z-score: 2626.1 bits: 498.5 E(85289): 1.5e-139
Smith-Waterman score: 10021; 96.8% identity (96.8% similar) in 1484 aa overlap (1-1484:1-1436)
10 20 30 40 50 60
pF1KE2 MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGKSNGELSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGKSNGELSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SRESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDP
::::::::: :::::::::::::::::::::::::::::::
XP_011 LEEKVKAVE--------------------DRAKRRKLREERAWLLAQGKELPPELSHLDP
370 380 390 400
430 440 450 460 470 480
pF1KE2 NSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMD
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE2 ISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFP
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE2 GEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPT
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE2 RRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLR
:::::::::::::::::::: ::::::::::::
XP_011 RRAPSSGDDQSSSSTQPPRE----------------------------RPAVPGTFGPLR
590 600 610
670 680 690 700 710 720
pF1KE2 GSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLS
620 630 640 650 660 670
730 740 750 760 770 780
pF1KE2 NMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMY
680 690 700 710 720 730
790 800 810 820 830 840
pF1KE2 RSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPP
740 750 760 770 780 790
850 860 870 880 890 900
pF1KE2 NQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMM
800 810 820 830 840 850
910 920 930 940 950 960
pF1KE2 DSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRA
860 870 880 890 900 910
970 980 990 1000 1010 1020
pF1KE2 PENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERET
920 930 940 950 960 970
1030 1040 1050 1060 1070 1080
pF1KE2 VGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGE
980 990 1000 1010 1020 1030
1090 1100 1110 1120 1130 1140
pF1KE2 ASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLY
1040 1050 1060 1070 1080 1090
1150 1160 1170 1180 1190 1200
pF1KE2 MPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQ
1100 1110 1120 1130 1140 1150
1210 1220 1230 1240 1250 1260
pF1KE2 GMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDK
1160 1170 1180 1190 1200 1210
1270 1280 1290 1300 1310 1320
pF1KE2 NAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLD
1220 1230 1240 1250 1260 1270
1330 1340 1350 1360 1370 1380
pF1KE2 NHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQP
1280 1290 1300 1310 1320 1330
1390 1400 1410 1420 1430 1440
pF1KE2 RAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQE
1340 1350 1360 1370 1380 1390
1450 1460 1470 1480
pF1KE2 MYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPPTLPLDQS
::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPPTLPLDQS
1400 1410 1420 1430
>>XP_011544434 (OMIM: 607576) PREDICTED: cat eye syndrom (1409 aa)
initn: 6283 init1: 3797 opt: 3844 Z-score: 1666.9 bits: 321.0 E(85289): 4.2e-86
Smith-Waterman score: 9767; 94.9% identity (94.9% similar) in 1484 aa overlap (1-1484:1-1409)
10 20 30 40 50 60
pF1KE2 MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 ACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 CDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGKSNGELSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGKSNGELSL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 SRESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 GTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 LHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 LEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDP
::::::::: :::::::::::::::::::::::::::::::
XP_011 LEEKVKAVE--------------------DRAKRRKLREERAWLLAQGKELPPELSHLDP
370 380 390 400
430 440 450 460 470 480
pF1KE2 NSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMD
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE2 ISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFP
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE2 GEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPT
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE2 RRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLR
590 600 610 620 630 640
670 680 690 700 710 720
pF1KE2 GSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLS
650 660 670 680 690 700
730 740 750 760 770 780
pF1KE2 NMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMY
710 720 730 740 750 760
790 800 810 820 830 840
pF1KE2 RSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPP
770 780 790 800 810 820
850 860 870 880 890 900
pF1KE2 NQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMM
830 840 850 860 870 880
910 920 930 940 950 960
pF1KE2 DSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRA
::::::::::::::::::
XP_011 DSPEMIAMQQLSSRVCPP------------------------------------------
890
970 980 990 1000 1010 1020
pF1KE2 PENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERET
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -------------AEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERET
900 910 920 930 940
1030 1040 1050 1060 1070 1080
pF1KE2 VGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGE
950 960 970 980 990 1000
1090 1100 1110 1120 1130 1140
pF1KE2 ASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLY
1010 1020 1030 1040 1050 1060
1150 1160 1170 1180 1190 1200
pF1KE2 MPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQ
1070 1080 1090 1100 1110 1120
1210 1220 1230 1240 1250 1260
pF1KE2 GMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDK
1130 1140 1150 1160 1170 1180
1270 1280 1290 1300 1310 1320
pF1KE2 NAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLD
1190 1200 1210 1220 1230 1240
1330 1340 1350 1360 1370 1380
pF1KE2 NHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQP
1250 1260 1270 1280 1290 1300
1390 1400 1410 1420 1430 1440
pF1KE2 RAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQE
1310 1320 1330 1340 1350 1360
1450 1460 1470 1480
pF1KE2 MYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPPTLPLDQS
::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPPTLPLDQS
1370 1380 1390 1400
>>XP_011515189 (OMIM: 610026) PREDICTED: collagen alpha- (1264 aa)
initn: 134 init1: 94 opt: 385 Z-score: 184.8 bits: 46.6 E(85289): 0.0015
Smith-Waterman score: 409; 25.9% identity (45.3% similar) in 896 aa overlap (639-1480:100-951)
610 620 630 640 650 660
pF1KE2 DQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLRGSDPATLY
: :. ... : : : ::. .
XP_011 VPIDFDLQRIVIYCDSRHAELETCCDIPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFL
70 80 90 100 110 120
670 680 690 700 710 720
pF1KE2 GS--SGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCG--GLTHLSNMGP
. . : . :: . :. . : : . :: .:.: : : :. ... :
XP_011 KTINCSCPAGEKGE-MGVAGPMGLPGPKGDIGAIGP-VGAPGPKGEKGDVGIGPFGQ-GE
130 140 150 160 170 180
730 740 750 760 770
pF1KE2 HPGSLQLGQISGPSQDGS--MYA-PAQF-QPGFIPPRHGG-APARPPDFPESSEIPPSHM
. . .:: . :..::: : . :... .:: .: . : .: :: .: ::...
XP_011 KGEKGSLGLPGPPGRDGSKGMRGEPGELGEPG-LPGEVGMRGPQGPPGLPG----PPGRV
190 200 210 220 230 240
780 790 800 810 820 830
pF1KE2 YRSYKYLNRVHSAVWNGNHGATN-QG-PLGPDEKPHLG-PGPSHQPRTLGHVMDSRVMRP
.: .... :..: . .: : : . . : :::: :. : :
XP_011 GAPGLQGERGEKGT-RGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGP
250 260 270 280 290 300
840 850 860 870 880 890
pF1KE2 PVPPNQWTEQSGFL-PHGVPSS-GYMRPPCKSAGHRLQPPPVPAPSSLFGAPA-QALRGV
: :.. ..: :. .:.:. :.. : : : :. .: . : :. :.:::
XP_011 PGVPGSVVQQEGLKGEQGAPGPRGHQGAP-GPPGAR---GPI-GPEGRDGPPGLQGLRG-
310 320 330 340 350
900 910 920 930 940 950
pF1KE2 QGGDSMMDSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGP--FPQVAHPMSVTVSAPK
. :: : : . .. :.. ::::: : . : ::: :: : . : :
XP_011 KKGD--MGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGK
360 370 380 390 400 410
960 970 980 990 1000
pF1KE2 --PALGNPGRAPENSEAQEPENDQAEPLPGL--EEKPPGVGTSEGVYLTQLPHPTPPLQT
: : :: ..: : .: ::: : :.. : . : :
XP_011 DGPN-GPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPG-EKGEAGLPGAPGFP
420 430 440 450 460 470
1010 1020 1030 1040 1050 1060
pF1KE2 DCTRQSSPQ-ERETVG-PELKSSSSESADNCKAMKGKNPWPSDSSY--PGPAAQGCVRDL
... : :. .: : ::.. .:... : : :. .: : : :
XP_011 GVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPA--GPPGLPGTTSLFTPHPRMPGEQGPK
480 490 500 510 520
1070 1080 1090 1100 1110 1120
pF1KE2 STVADRGALSENGVIG---EASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAAT
. .: : .: :. : : .: : : :..:.: : . . : :. .:
XP_011 GEKGDPGLPGEPGLQGRPGELGPQGPTGPP-GAKGQEGAHGAPGAAGNPGAP--GHVGAP
530 540 550 560 570 580
1130 1140 1150 1160 1170 1180
pF1KE2 PPSTDPGLTGGTVSQFPPLYMPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPP
:: :: .:. . : : . ..:: . ::: ::: : . . : ::
XP_011 GPSGPPGSVGAPGLRGTP-GKDGERGEKGAAGEEGSPG--PVGP-RGDPGAPGLPG--PP
590 600 610 620 630
1190 1200 1210 1220 1230
pF1KE2 RGFQSNHPHSGGFPRYRPPQGMRYSYHPPPQPSYHHYQRTPYY--ACPQSFSDWQRPLHP
....: : : : : . . : :. . : : : . : :
XP_011 GKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSG---PPGD
640 650 660 670 680 690
1240 1250 1260 1270 1280 1290
pF1KE2 QGSPS-----GPPASQPPPPRSLFSDKNAMASLQGCETLNAALTSPTRMDAVAAKVPNDG
.:::. : :. : : :. . . . : :.. : :: .. .: : ::
XP_011 KGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSS-LLSPGDINLLAKDVCNDC
700 710 720 730 740 750
1300 1310 1320 1330 1340
pF1KE2 QNPGPEEE------KLDESMERPESP-KEFLDLDNHNAATKRQSSLSASEYLYGTPPPLS
::: : :... : .: .: . . .:. . . :. .
XP_011 P-PGPPGLPGLPGFKGDKGV--PGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG
760 770 780 790 800 810
1350 1360 1370 1380 1390 1400
pF1KE2 SGMGFGSSAFPPH-SVMLQTGPPYTPQRPASHFQPRAYSSP-VAALPPHH--PGATQPNG
. :... : .: ::: .: :.. : . : . . : .. :: :.:
XP_011 ADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSG
820 830 840 850 860 870
1410 1420 1430 1440 1450
pF1KE2 L----SQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQEMYR-PSGMQMHPVQSQAS
: ..:: : . : . : :. :: : : : :.. : .: :
XP_011 LPGIPGEEGKEGRDGKPGPPGEPGKAGEP-----GLPGP--EGARGPPGFKGHTGDSGAP
880 890 900 910 920
1460 1470 1480
pF1KE2 FPKTPTAATS---QEEVPPHKPPTLPLDQS
:. ..: . :: .: . : :
XP_011 GPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQK
930 940 950 960 970 980
>>XP_016868641 (OMIM: 610026) PREDICTED: collagen alpha- (1264 aa)
initn: 134 init1: 94 opt: 385 Z-score: 184.8 bits: 46.6 E(85289): 0.0015
Smith-Waterman score: 409; 25.9% identity (45.3% similar) in 896 aa overlap (639-1480:100-951)
610 620 630 640 650 660
pF1KE2 DQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLRGSDPATLY
: :. ... : : : ::. .
XP_016 VPIDFDLQRIVIYCDSRHAELETCCDIPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFL
70 80 90 100 110 120
670 680 690 700 710 720
pF1KE2 GS--SGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCG--GLTHLSNMGP
. . : . :: . :. . : : . :: .:.: : : :. ... :
XP_016 KTINCSCPAGEKGE-MGVAGPMGLPGPKGDIGAIGP-VGAPGPKGEKGDVGIGPFGQ-GE
130 140 150 160 170 180
730 740 750 760 770
pF1KE2 HPGSLQLGQISGPSQDGS--MYA-PAQF-QPGFIPPRHGG-APARPPDFPESSEIPPSHM
. . .:: . :..::: : . :... .:: .: . : .: :: .: ::...
XP_016 KGEKGSLGLPGPPGRDGSKGMRGEPGELGEPG-LPGEVGMRGPQGPPGLPG----PPGRV
190 200 210 220 230 240
780 790 800 810 820 830
pF1KE2 YRSYKYLNRVHSAVWNGNHGATN-QG-PLGPDEKPHLG-PGPSHQPRTLGHVMDSRVMRP
.: .... :..: . .: : : . . : :::: :. : :
XP_016 GAPGLQGERGEKGT-RGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGP
250 260 270 280 290 300
840 850 860 870 880 890
pF1KE2 PVPPNQWTEQSGFL-PHGVPSS-GYMRPPCKSAGHRLQPPPVPAPSSLFGAPA-QALRGV
: :.. ..: :. .:.:. :.. : : : :. .: . : :. :.:::
XP_016 PGVPGSVVQQEGLKGEQGAPGPRGHQGAP-GPPGAR---GPI-GPEGRDGPPGLQGLRG-
310 320 330 340 350
900 910 920 930 940 950
pF1KE2 QGGDSMMDSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGP--FPQVAHPMSVTVSAPK
. :: : : . .. :.. ::::: : . : ::: :: : . : :
XP_016 KKGD--MGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGK
360 370 380 390 400 410
960 970 980 990 1000
pF1KE2 --PALGNPGRAPENSEAQEPENDQAEPLPGL--EEKPPGVGTSEGVYLTQLPHPTPPLQT
: : :: ..: : .: ::: : :.. : . : :
XP_016 DGPN-GPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPG-EKGEAGLPGAPGFP
420 430 440 450 460 470
1010 1020 1030 1040 1050 1060
pF1KE2 DCTRQSSPQ-ERETVG-PELKSSSSESADNCKAMKGKNPWPSDSSY--PGPAAQGCVRDL
... : :. .: : ::.. .:... : : :. .: : : :
XP_016 GVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPA--GPPGLPGTTSLFTPHPRMPGEQGPK
480 490 500 510 520
1070 1080 1090 1100 1110 1120
pF1KE2 STVADRGALSENGVIG---EASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAAT
. .: : .: :. : : .: : : :..:.: : . . : :. .:
XP_016 GEKGDPGLPGEPGLQGRPGELGPQGPTGPP-GAKGQEGAHGAPGAAGNPGAP--GHVGAP
530 540 550 560 570 580
1130 1140 1150 1160 1170 1180
pF1KE2 PPSTDPGLTGGTVSQFPPLYMPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPP
:: :: .:. . : : . ..:: . ::: ::: : . . : ::
XP_016 GPSGPPGSVGAPGLRGTP-GKDGERGEKGAAGEEGSPG--PVGP-RGDPGAPGLPG--PP
590 600 610 620 630
1190 1200 1210 1220 1230
pF1KE2 RGFQSNHPHSGGFPRYRPPQGMRYSYHPPPQPSYHHYQRTPYY--ACPQSFSDWQRPLHP
....: : : : : . . : :. . : : : . : :
XP_016 GKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSG---PPGD
640 650 660 670 680 690
1240 1250 1260 1270 1280 1290
pF1KE2 QGSPS-----GPPASQPPPPRSLFSDKNAMASLQGCETLNAALTSPTRMDAVAAKVPNDG
.:::. : :. : : :. . . . : :.. : :: .. .: : ::
XP_016 KGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSS-LLSPGDINLLAKDVCNDC
700 710 720 730 740 750
1300 1310 1320 1330 1340
pF1KE2 QNPGPEEE------KLDESMERPESP-KEFLDLDNHNAATKRQSSLSASEYLYGTPPPLS
::: : :... : .: .: . . .:. . . :. .
XP_016 P-PGPPGLPGLPGFKGDKGV--PGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG
760 770 780 790 800 810
1350 1360 1370 1380 1390 1400
pF1KE2 SGMGFGSSAFPPH-SVMLQTGPPYTPQRPASHFQPRAYSSP-VAALPPHH--PGATQPNG
. :... : .: ::: .: :.. : . : . . : .. :: :.:
XP_016 ADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSG
820 830 840 850 860 870
1410 1420 1430 1440 1450
pF1KE2 L----SQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQEMYR-PSGMQMHPVQSQAS
: ..:: : . : . : :. :: : : : :.. : .: :
XP_016 LPGIPGEEGKEGRDGKPGPPGEPGKAGEP-----GLPGP--EGARGPPGFKGHTGDSGAP
880 890 900 910 920
1460 1470 1480
pF1KE2 FPKTPTAATS---QEEVPPHKPPTLPLDQS
:. ..: . :: .: . : :
XP_016 GPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQK
930 940 950 960 970 980
>>XP_011515190 (OMIM: 610026) PREDICTED: collagen alpha- (1195 aa)
initn: 146 init1: 94 opt: 384 Z-score: 184.7 bits: 46.5 E(85289): 0.0015
Smith-Waterman score: 386; 26.8% identity (46.1% similar) in 694 aa overlap (639-1298:442-1101)
610 620 630 640 650 660
pF1KE2 DQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLRGSDPATLY
: :. ... : : : ::. .
XP_011 VPIDFDLQRIVIYCDSRHAELETCCDIPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFL
420 430 440 450 460 470
670 680 690 700 710 720
pF1KE2 GS--SGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCG--GLTHLSNMGP
. . : . :: . :. . : : . :: .:.: : : :. ... :
XP_011 KTINCSCPAGEKGE-MGVAGPMGLPGPKGDIGAIGP-VGAPGPKGEKGDVGIGPFGQ-GE
480 490 500 510 520
730 740 750 760 770
pF1KE2 HPGSLQLGQISGPSQDGS--MYA-PAQF-QPGFIPPRHGG-APARPPDFPESSEIPPSHM
. . .:: . :..::: : . :... .:: .: . : .: :: .: ::...
XP_011 KGEKGSLGLPGPPGRDGSKGMRGEPGELGEPG-LPGEVGMRGPQGPPGLPG----PPGRV
530 540 550 560 570 580
780 790 800 810 820 830
pF1KE2 YRSYKYLNRVHSAVWNGNHGATN-QG-PLGPDEKPHLG-PGPSHQPRTLGHVMDSRVMRP
.: .... :..: . .: : : . . : :::: :. : :
XP_011 GAPGLQGERGEKGT-RGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGP
590 600 610 620 630 640
840 850 860 870 880 890
pF1KE2 PVPPNQWTEQSGFL-PHGVPSS-GYMRPPCKSAGHRLQPPPVPAPSSLFGAPA-QALRGV
: :.. ..: :. .:.:. :.. : : : :. .: . : :. :.:::
XP_011 PGVPGSVVQQEGLKGEQGAPGPRGHQGAP-GPPGAR---GPI-GPEGRDGPPGLQGLRG-
650 660 670 680 690
900 910 920 930 940 950
pF1KE2 QGGDSMMDSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGP--FPQVAHPMSVTVSAPK
. :: : : . .. :.. ::::: : . : ::: :: : . : :
XP_011 KKGD--MGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGK
700 710 720 730 740 750
960 970 980 990 1000
pF1KE2 PAL-GNPGRAPENSEAQEPENDQAEPLPGL--EEKPPGVGTSEGVYLTQLPHPTPPLQTD
. : :: ..: : .: ::: : :.. : . : :
XP_011 DGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPG-EKGEAGLPGAPGFPG
760 770 780 790 800 810
1010 1020 1030 1040 1050 1060
pF1KE2 CTRQSSPQ-ERETVG-PELKSSSSESADNCKAMKGKNPWPSDSSY--PGPAAQGCVRDLS
... : :. .: : ::.. .:... : : :. .: : : : .
XP_011 VRGEKGDQGEKGELGLPGLKGDRGEKGEAGPA--GPPGLPGTTSLFTPHPRMPGEQGPKG
820 830 840 850 860 870
1070 1080 1090 1100 1110 1120
pF1KE2 TVADRGALSENGVIG---EASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATP
.: : .: :. : : .: : : :..:.: : . . : :. .:
XP_011 EKGDPGLPGEPGLQGRPGELGPQGPTGPP-GAKGQEGAHGAPGAAGNPGAP--GHVGAPG
880 890 900 910 920
1130 1140 1150 1160 1170 1180
pF1KE2 PSTDPGLTGGTVSQFPPLYMPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPR
:: :: .:. . : : . ..:: . ::: ::: : . . : ::
XP_011 PSGPPGSVGAPGLRGTP-GKDGERGEKGAAGEEGSPG--PVGP-RGDPGAPGLPG--PPG
930 940 950 960 970 980
1190 1200 1210 1220 1230
pF1KE2 GFQSNHPHSGGFPRYRPPQGMRYSYHPPPQPSYHHYQRTPYY--ACPQSFSDWQRPLHPQ
....: : : : : . . : :. . : : : . : : .
XP_011 KGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSG---PPGDK
990 1000 1010 1020 1030
1240 1250 1260 1270 1280 1290
pF1KE2 GSPS-----GPPASQPPPPRSLFSDKNAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQ
:::. : :. : : :. . . . : :.. : :: .. .: : ::
XP_011 GSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSS-LLSPGDINLLAKDVCNDCP
1040 1050 1060 1070 1080 1090
1300 1310 1320 1330 1340 1350
pF1KE2 NPGPEEEKLDESMERPESPKEFLDLDNHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSS
:::
XP_011 -PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADG
1100 1110 1120 1130 1140 1150
1484 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 09:23:00 2016 done: Sun Nov 6 09:23:03 2016
Total Scan time: 22.150 Total Display time: 0.600
Function used was FASTA [36.3.4 Apr, 2011]