Result of FASTA (omim) for
pFN21AE5414
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE5414, 349 aa
1>>>pF1KE5414 349 - 349 aa - 349 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7879+/-0.000318; mu= 15.6923+/- 0.020
mean_var=98.4611+/-19.435, 0's: 0 Z-trim(118.0): 9 B-trim: 229 in 1/58
Lambda= 0.129253
statistics sampled from 30556 (30565) to 30556 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.718), E-opt: 0.2 (0.358), width: 16
Scan time: 7.510
The best scores are: opt bits E(85289)
NP_001307233 (OMIM: 612981) U3 small nucleolar rib ( 289) 472 97.9 2.9e-20
NP_219484 (OMIM: 612981) U3 small nucleolar ribonu ( 291) 467 97.0 5.5e-20
NP_001307235 (OMIM: 612981) U3 small nucleolar rib ( 236) 446 93.0 7.2e-19
NP_001307236 (OMIM: 612981) U3 small nucleolar rib ( 236) 446 93.0 7.2e-19
NP_001307239 (OMIM: 612981) U3 small nucleolar rib ( 206) 426 89.2 8.6e-18
NP_001307238 (OMIM: 612981) U3 small nucleolar rib ( 206) 426 89.2 8.6e-18
NP_001307240 (OMIM: 612981) U3 small nucleolar rib ( 203) 410 86.2 6.7e-17
NP_001307234 (OMIM: 612981) U3 small nucleolar rib ( 273) 397 83.9 4.5e-16
>>NP_001307233 (OMIM: 612981) U3 small nucleolar ribonuc (289 aa)
initn: 414 init1: 233 opt: 472 Z-score: 484.8 bits: 97.9 E(85289): 2.9e-20
Smith-Waterman score: 472; 30.2% identity (63.2% similar) in 291 aa overlap (60-349:7-286)
30 40 50 60 70 80
pF1KE5 GAGDGATENGVQPPKAAAFPPGFSISEIKNKQRRHLMFTRWKQQQRKEKLAAKKKLKKER
. ::. .. . ... .. .:... .. :
NP_001 MLRREARLRREYLYRKAREEAQR---SAQERKERLR
10 20 30
90 100 110 120 130 140
pF1KE5 EALGDKAPPKPVPKTIDNQRVYDETTVDPNDEEVAYDEATDEFASYFNKQTSPKILITTS
.:: .. . .: . . . . ... .: . ... ::. . .::..::::
NP_001 RALEEN---RLIPTELRREALALQGSLEFDDAGGVTSHVDDEY--RWAGVEDPKVMITTS
40 50 60 70 80
150 160 170 180 190 200
pF1KE5 DRPHGRTVRLCEQLSTVIPNSHVYYRRGLALKKIIPQCIARDFTDLIVINEDRKTPNGLI
: .: . ..:. :.:... . : . .. : : :::.:..: : :: :::
NP_001 RDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLI
90 100 110 120 130 140
210 220 230 240 250 260
pF1KE5 LSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHIPEIILNNFTTRLGHSIGRMFASLFPH
.:::: ::::.: . .: .:..: : .: :..: ..:..:::. .. .. :::
NP_001 VSHLPFGPTAYFTLCNVVMRHDIPDLGT-MSEAKPHLITHGFSSRLGKRVSDILRYLFP-
150 160 170 180 190 200
270 280 290 300 310 320
pF1KE5 NPQFIGRQVATFHNQRDYIFFRFHRYIFRSEKKVGIQELGPRFTLKLRSLQKGTFDSKY-
:. ...: :: :: ::: :: : : ....: . :.:::: ::: .. ::....
NP_001 VPKDDSHRVITFANQDDYISFRHHVYKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEAT
210 220 230 240 250 260
330 340
pF1KE5 GEYEWVHKPREMDTSRRKFHL
.. :: .: .:.:.. :
NP_001 ADVEWRWHPYT-NTARKRVFLSTE
270 280
>>NP_219484 (OMIM: 612981) U3 small nucleolar ribonucleo (291 aa)
initn: 440 init1: 233 opt: 467 Z-score: 479.7 bits: 97.0 E(85289): 5.5e-20
Smith-Waterman score: 467; 30.4% identity (63.1% similar) in 293 aa overlap (60-349:7-288)
30 40 50 60 70 80
pF1KE5 GAGDGATENGVQPPKAAAFPPGFSISEIKNKQRRHLMFTRWKQQQRKEKLAAKKKLKKER
. ::. .. . ... .. .:... .. :
NP_219 MLRREARLRREYLYRKAREEAQR---SAQERKERLR
10 20 30
90 100 110 120 130 140
pF1KE5 EALGDKAPPKPVPKTIDNQRVYDETTVDPNDE--EVAYDEATDEFASYFNKQTSPKILIT
.:: .. . .: . . . . ... .: : . ... ::. . .::..::
NP_219 RALEEN---RLIPTELRREALALQGSLEFDDAGGEGVTSHVDDEY--RWAGVEDPKVMIT
40 50 60 70 80
150 160 170 180 190 200
pF1KE5 TSDRPHGRTVRLCEQLSTVIPNSHVYYRRGLALKKIIPQCIARDFTDLIVINEDRKTPNG
:: : .: . ..:. :.:... . : . .. : : :::.:..: : :: :
NP_219 TSRDPSSRLKMFAKELKLVFPGAQRMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVG
90 100 110 120 130 140
210 220 230 240 250 260
pF1KE5 LILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHIPEIILNNFTTRLGHSIGRMFASLF
::.:::: ::::.: . .: .:..: : .: :..: ..:..:::. .. .. ::
NP_219 LIVSHLPFGPTAYFTLCNVVMRHDIPDLGT-MSEAKPHLITHGFSSRLGKRVSDILRYLF
150 160 170 180 190 200
270 280 290 300 310 320
pF1KE5 PHNPQFIGRQVATFHNQRDYIFFRFHRYIFRSEKKVGIQELGPRFTLKLRSLQKGTFDSK
: :. ...: :: :: ::: :: : : ....: . :.:::: ::: .. ::....
NP_219 P-VPKDDSHRVITFANQDDYISFRHHVYKKTDHRNVELTEVGPRFELKLYMIRLGTLEQE
210 220 230 240 250 260
330 340
pF1KE5 Y-GEYEWVHKPREMDTSRRKFHL
.. :: .: .:.:.. :
NP_219 ATADVEWRWHPYT-NTARKRVFLSTE
270 280 290
>>NP_001307235 (OMIM: 612981) U3 small nucleolar ribonuc (236 aa)
initn: 414 init1: 233 opt: 446 Z-score: 459.8 bits: 93.0 E(85289): 7.2e-19
Smith-Waterman score: 446; 37.3% identity (66.0% similar) in 209 aa overlap (142-349:28-233)
120 130 140 150 160 170
pF1KE5 DETTVDPNDEEVAYDEATDEFASYFNKQTSPKILITTSDRPHGRTVRLCEQLSTVIPNSH
::..:::: : .: . ..:. :.:...
NP_001 MMLEVKVTIQGVTSHVDDEYRWAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQ
10 20 30 40 50
180 190 200 210 220 230
pF1KE5 VYYRRGLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKE
. : . .. : : :::.:..: : :: :::.:::: ::::.: . .: .:..
NP_001 RMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHD
60 70 80 90 100 110
240 250 260 270 280 290
pF1KE5 IKRRGKDPTEHIPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFR
: : .: :..: ..:..:::. .. .. ::: :. ...: :: :: ::: ::
NP_001 IPDLGT-MSEAKPHLITHGFSSRLGKRVSDILRYLFP-VPKDDSHRVITFANQDDYISFR
120 130 140 150 160 170
300 310 320 330 340
pF1KE5 FHRYIFRSEKKVGIQELGPRFTLKLRSLQKGTFDSKY-GEYEWVHKPREMDTSRRKFHL
: : ....: . :.:::: ::: .. ::.... .. :: .: .:.:.. :
NP_001 HHVYKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYT-NTARKRVFLS
180 190 200 210 220 230
NP_001 TE
>>NP_001307236 (OMIM: 612981) U3 small nucleolar ribonuc (236 aa)
initn: 414 init1: 233 opt: 446 Z-score: 459.8 bits: 93.0 E(85289): 7.2e-19
Smith-Waterman score: 446; 37.3% identity (66.0% similar) in 209 aa overlap (142-349:28-233)
120 130 140 150 160 170
pF1KE5 DETTVDPNDEEVAYDEATDEFASYFNKQTSPKILITTSDRPHGRTVRLCEQLSTVIPNSH
::..:::: : .: . ..:. :.:...
NP_001 MMLEVKVTIQGVTSHVDDEYRWAGVEDPKVMITTSRDPSSRLKMFAKELKLVFPGAQ
10 20 30 40 50
180 190 200 210 220 230
pF1KE5 VYYRRGLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKE
. : . .. : : :::.:..: : :: :::.:::: ::::.: . .: .:..
NP_001 RMNRGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHD
60 70 80 90 100 110
240 250 260 270 280 290
pF1KE5 IKRRGKDPTEHIPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFR
: : .: :..: ..:..:::. .. .. ::: :. ...: :: :: ::: ::
NP_001 IPDLGT-MSEAKPHLITHGFSSRLGKRVSDILRYLFP-VPKDDSHRVITFANQDDYISFR
120 130 140 150 160 170
300 310 320 330 340
pF1KE5 FHRYIFRSEKKVGIQELGPRFTLKLRSLQKGTFDSKY-GEYEWVHKPREMDTSRRKFHL
: : ....: . :.:::: ::: .. ::.... .. :: .: .:.:.. :
NP_001 HHVYKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYT-NTARKRVFLS
180 190 200 210 220 230
NP_001 TE
>>NP_001307239 (OMIM: 612981) U3 small nucleolar ribonuc (206 aa)
initn: 337 init1: 156 opt: 426 Z-score: 440.4 bits: 89.2 E(85289): 8.6e-18
Smith-Waterman score: 426; 36.9% identity (65.5% similar) in 206 aa overlap (145-349:1-203)
120 130 140 150 160 170
pF1KE5 TVDPNDEEVAYDEATDEFASYFNKQTSPKILITTSDRPHGRTVRLCEQLSTVIPNSHVYY
.:::: : .: . ..:. :.:... .
NP_001 MITTSRDPSSRLKMFAKELKLVFPGAQRMN
10 20 30
180 190 200 210 220 230
pF1KE5 RRGLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKEIKR
: . .. : : :::.:..: : :: :::.:::: ::::.: . .: .:..:
NP_001 RGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPD
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE5 RGKDPTEHIPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHR
: .: :..: ..:..:::. .. .. ::: :. ...: :: :: ::: :: :
NP_001 LGT-MSEAKPHLITHGFSSRLGKRVSDILRYLFP-VPKDDSHRVITFANQDDYISFRHHV
100 110 120 130 140
300 310 320 330 340
pF1KE5 YIFRSEKKVGIQELGPRFTLKLRSLQKGTFDSKY-GEYEWVHKPREMDTSRRKFHL
: ....: . :.:::: ::: .. ::.... .. :: .: .:.:.. :
NP_001 YKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYT-NTARKRVFLSTE
150 160 170 180 190 200
>>NP_001307238 (OMIM: 612981) U3 small nucleolar ribonuc (206 aa)
initn: 337 init1: 156 opt: 426 Z-score: 440.4 bits: 89.2 E(85289): 8.6e-18
Smith-Waterman score: 426; 36.9% identity (65.5% similar) in 206 aa overlap (145-349:1-203)
120 130 140 150 160 170
pF1KE5 TVDPNDEEVAYDEATDEFASYFNKQTSPKILITTSDRPHGRTVRLCEQLSTVIPNSHVYY
.:::: : .: . ..:. :.:... .
NP_001 MITTSRDPSSRLKMFAKELKLVFPGAQRMN
10 20 30
180 190 200 210 220 230
pF1KE5 RRGLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKEIKR
: . .. : : :::.:..: : :: :::.:::: ::::.: . .: .:..:
NP_001 RGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPD
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE5 RGKDPTEHIPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHR
: .: :..: ..:..:::. .. .. ::: :. ...: :: :: ::: :: :
NP_001 LGT-MSEAKPHLITHGFSSRLGKRVSDILRYLFP-VPKDDSHRVITFANQDDYISFRHHV
100 110 120 130 140
300 310 320 330 340
pF1KE5 YIFRSEKKVGIQELGPRFTLKLRSLQKGTFDSKY-GEYEWVHKPREMDTSRRKFHL
: ....: . :.:::: ::: .. ::.... .. :: .: .:.:.. :
NP_001 YKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYT-NTARKRVFLSTE
150 160 170 180 190 200
>>NP_001307240 (OMIM: 612981) U3 small nucleolar ribonuc (203 aa)
initn: 337 init1: 156 opt: 410 Z-score: 424.4 bits: 86.2 E(85289): 6.7e-17
Smith-Waterman score: 410; 36.9% identity (65.5% similar) in 206 aa overlap (145-349:1-200)
120 130 140 150 160 170
pF1KE5 TVDPNDEEVAYDEATDEFASYFNKQTSPKILITTSDRPHGRTVRLCEQLSTVIPNSHVYY
.:::: : .: ... .: :.:... .
NP_001 MITTSRDPSSR-LKMFAKL--VFPGAQRMN
10 20
180 190 200 210 220 230
pF1KE5 RRGLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKEIKR
: . .. : : :::.:..: : :: :::.:::: ::::.: . .: .:..:
NP_001 RGRHEVGALVRACKANGVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPD
30 40 50 60 70 80
240 250 260 270 280 290
pF1KE5 RGKDPTEHIPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHR
: .: :..: ..:..:::. .. .. ::: :. ...: :: :: ::: :: :
NP_001 LGT-MSEAKPHLITHGFSSRLGKRVSDILRYLFP-VPKDDSHRVITFANQDDYISFRHHV
90 100 110 120 130 140
300 310 320 330 340
pF1KE5 YIFRSEKKVGIQELGPRFTLKLRSLQKGTFDSKY-GEYEWVHKPREMDTSRRKFHL
: ....: . :.:::: ::: .. ::.... .. :: .: .:.:.. :
NP_001 YKKTDHRNVELTEVGPRFELKLYMIRLGTLEQEATADVEWRWHPYT-NTARKRVFLSTE
150 160 170 180 190 200
>>NP_001307234 (OMIM: 612981) U3 small nucleolar ribonuc (273 aa)
initn: 363 init1: 156 opt: 397 Z-score: 409.6 bits: 83.9 E(85289): 4.5e-16
Smith-Waterman score: 397; 36.8% identity (66.3% similar) in 190 aa overlap (161-349:84-270)
140 150 160 170 180 190
pF1KE5 EFASYFNKQTSPKILITTSDRPHGRTVRLCEQLSTVIPNSHVYYRRGLALKKIIPQCIAR
..:. :.:... . : . .. : :
NP_001 QGSLEFDDAGGEGVTSHVDDEYRWAGVEDPKELKLVFPGAQRMNRGRHEVGALVRACKAN
60 70 80 90 100 110
200 210 220 230 240 250
pF1KE5 DFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHIPEIILNN
:::.:..: : :: :::.:::: ::::.: . .: .:..: : .: :..: ..
NP_001 GVTDLLVVHEHRGTPVGLIVSHLPFGPTAYFTLCNVVMRHDIPDLGT-MSEAKPHLITHG
120 130 140 150 160 170
260 270 280 290 300 310
pF1KE5 FTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFRSEKKVGIQELGP
:..:::. .. .. ::: :. ...: :: :: ::: :: : : ....: . :.::
NP_001 FSSRLGKRVSDILRYLFP-VPKDDSHRVITFANQDDYISFRHHVYKKTDHRNVELTEVGP
180 190 200 210 220 230
320 330 340
pF1KE5 RFTLKLRSLQKGTFDSKY-GEYEWVHKPREMDTSRRKFHL
:: ::: .. ::.... .. :: .: .:.:.. :
NP_001 RFELKLYMIRLGTLEQEATADVEWRWHPYT-NTARKRVFLSTE
240 250 260 270
349 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 00:30:59 2016 done: Tue Nov 8 00:31:01 2016
Total Scan time: 7.510 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]