Result of FASTA (omim) for
pFN21AB9280
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9280, 579 aa
1>>>pF1KB9280 579 - 579 aa - 579 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3970+/-0.000429; mu= 12.0573+/- 0.027
mean_var=229.4398+/-47.869, 0's: 0 Z-trim(117.3): 59 B-trim: 77 in 1/54
Lambda= 0.084672
statistics sampled from 29171 (29230) to 29171 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.343), width: 16
Scan time: 10.640
The best scores are: opt bits E(85289)
NP_067627 (OMIM: 605879) small conductance calcium ( 579) 3747 471.2 4e-132
XP_011541689 (OMIM: 605879) PREDICTED: small condu ( 857) 3747 471.4 5.1e-132
XP_011541691 (OMIM: 605879) PREDICTED: small condu ( 857) 3747 471.4 5.1e-132
NP_002240 (OMIM: 602983) small conductance calcium ( 731) 2561 326.5 1.9e-88
XP_005259964 (OMIM: 602982) PREDICTED: small condu ( 623) 2359 301.7 4.6e-81
NP_002239 (OMIM: 602982) small conductance calcium ( 543) 2343 299.7 1.6e-80
XP_005259963 (OMIM: 602982) PREDICTED: small condu ( 626) 2343 299.8 1.8e-80
XP_011526306 (OMIM: 602982) PREDICTED: small condu ( 626) 2343 299.8 1.8e-80
XP_011526307 (OMIM: 602982) PREDICTED: small condu ( 546) 2327 297.7 6.4e-80
XP_005259962 (OMIM: 602982) PREDICTED: small condu ( 629) 2327 297.8 6.9e-80
NP_740752 (OMIM: 602983) small conductance calcium ( 426) 2199 282.0 2.8e-75
XP_016864946 (OMIM: 605879) PREDICTED: small condu ( 275) 1575 205.5 1.9e-52
NP_001265133 (OMIM: 605879) small conductance calc ( 231) 1472 192.8 1e-48
NP_740721 (OMIM: 605879) small conductance calcium ( 231) 1472 192.8 1e-48
NP_001191016 (OMIM: 602983) small conductance calc ( 746) 1386 183.0 3.1e-45
NP_002241 (OMIM: 602754,616689) intermediate condu ( 427) 1131 151.5 5.2e-36
XP_005258939 (OMIM: 602754,616689) PREDICTED: inte ( 395) 947 129.0 2.9e-29
XP_005258940 (OMIM: 602754,616689) PREDICTED: inte ( 364) 625 89.6 1.9e-17
XP_011525240 (OMIM: 602754,616689) PREDICTED: inte ( 259) 533 78.2 3.7e-14
>>NP_067627 (OMIM: 605879) small conductance calcium-act (579 aa)
initn: 3747 init1: 3747 opt: 3747 Z-score: 2493.0 bits: 471.2 E(85289): 4e-132
Smith-Waterman score: 3747; 100.0% identity (100.0% similar) in 579 aa overlap (1-579:1-579)
10 20 30 40 50 60
pF1KB9 MSSCRYNGGVMRPLSNLSASRRNLHEMDSEAQPLQPPASVGGGGGASSPSAAAAAAAAVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 MSSCRYNGGVMRPLSNLSASRRNLHEMDSEAQPLQPPASVGGGGGASSPSAAAAAAAAVS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 SSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGHGSSSGTKSSKKKNQNIGYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 SSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGHGSSSGTKSSKKKNQNIGYK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 LGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTII
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 LLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 LLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTAR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 LAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 LAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 VMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 VMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 YGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 YGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 NAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 NAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 DLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLISQTIRQQQRDFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_067 DLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLISQTIRQQQRDFI
490 500 510 520 530 540
550 560 570
pF1KB9 EAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS
:::::::::::::::::::::::::::::::::::::::
NP_067 EAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS
550 560 570
>>XP_011541689 (OMIM: 605879) PREDICTED: small conductan (857 aa)
initn: 3747 init1: 3747 opt: 3747 Z-score: 2491.1 bits: 471.4 E(85289): 5.1e-132
Smith-Waterman score: 3747; 100.0% identity (100.0% similar) in 579 aa overlap (1-579:279-857)
10 20 30
pF1KB9 MSSCRYNGGVMRPLSNLSASRRNLHEMDSE
::::::::::::::::::::::::::::::
XP_011 SHHHHHPHPAHHQHHQPQARRESNPFTEIAMSSCRYNGGVMRPLSNLSASRRNLHEMDSE
250 260 270 280 290 300
40 50 60 70 80 90
pF1KB9 AQPLQPPASVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQPLQPPASVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGST
310 320 330 340 350 360
100 110 120 130 140 150
pF1KB9 GGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMV
370 380 390 400 410 420
160 170 180 190 200 210
pF1KB9 IETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMT
430 440 450 460 470 480
220 230 240 250 260 270
pF1KB9 YERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIA
490 500 510 520 530 540
280 290 300 310 320 330
pF1KB9 RVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVR
550 560 570 580 590 600
340 350 360 370 380 390
pF1KB9 ACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVV
610 620 630 640 650 660
400 410 420 430 440 450
pF1KB9 AVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRK
670 680 690 700 710 720
460 470 480 490 500 510
pF1KB9 HQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTL
730 740 750 760 770 780
520 530 540 550 560 570
pF1KB9 ETKLETLIGSIHALPGLISQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETKLETLIGSIHALPGLISQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSST
790 800 810 820 830 840
pF1KB9 APPTSSESS
:::::::::
XP_011 APPTSSESS
850
>>XP_011541691 (OMIM: 605879) PREDICTED: small conductan (857 aa)
initn: 3747 init1: 3747 opt: 3747 Z-score: 2491.1 bits: 471.4 E(85289): 5.1e-132
Smith-Waterman score: 3747; 100.0% identity (100.0% similar) in 579 aa overlap (1-579:279-857)
10 20 30
pF1KB9 MSSCRYNGGVMRPLSNLSASRRNLHEMDSE
::::::::::::::::::::::::::::::
XP_011 SHHHHHPHPAHHQHHQPQARRESNPFTEIAMSSCRYNGGVMRPLSNLSASRRNLHEMDSE
250 260 270 280 290 300
40 50 60 70 80 90
pF1KB9 AQPLQPPASVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQPLQPPASVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGST
310 320 330 340 350 360
100 110 120 130 140 150
pF1KB9 GGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMV
370 380 390 400 410 420
160 170 180 190 200 210
pF1KB9 IETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMT
430 440 450 460 470 480
220 230 240 250 260 270
pF1KB9 YERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIA
490 500 510 520 530 540
280 290 300 310 320 330
pF1KB9 RVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVR
550 560 570 580 590 600
340 350 360 370 380 390
pF1KB9 ACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVV
610 620 630 640 650 660
400 410 420 430 440 450
pF1KB9 AVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRK
670 680 690 700 710 720
460 470 480 490 500 510
pF1KB9 HQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTL
730 740 750 760 770 780
520 530 540 550 560 570
pF1KB9 ETKLETLIGSIHALPGLISQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETKLETLIGSIHALPGLISQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSST
790 800 810 820 830 840
pF1KB9 APPTSSESS
:::::::::
XP_011 APPTSSESS
850
>>NP_002240 (OMIM: 602983) small conductance calcium-act (731 aa)
initn: 2689 init1: 2525 opt: 2561 Z-score: 1708.9 bits: 326.5 E(85289): 1.9e-88
Smith-Waterman score: 2687; 73.7% identity (86.7% similar) in 579 aa overlap (1-579:175-728)
10 20 30
pF1KB9 MSSCRYNGGVMRPLSNLSASRRNLHEMDSE
::::.:.::::.::: :::::::: : ..:
NP_002 ATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAETE
150 160 170 180 190 200
40 50 60 70 80 90
pF1KB9 AQPLQPPASVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGGST
.:::: ::: . ::::.:. : :.... :. .. .
NP_002 GQPLQ----------LFSPS-----------NPPEIVISSREDNHAHQTLLHHPNATHNH
210 220 230 240
100 110 120 130 140 150
pF1KB9 GGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMV
.: . .:.. :..:.::::::::::::::::::::::::::::::::::::::
NP_002 QHAG----TTASSTTFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMV
250 260 270 280 290
160 170 180 190 200 210
pF1KB9 IETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMT
:::::::: :.: :..::::::::::::::::::::.::.::.:::..::::::::::::
NP_002 IETELSWGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMT
300 310 320 330 340 350
220 230 240 250 260 270
pF1KB9 YERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIA
::::..: ::.::::::::::.: : :::::::::.:: . :::::::::::::::::::
NP_002 YERILYISLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIA
360 370 380 390 400 410
280 290 300 310 320 330
pF1KB9 RVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVR
420 430 440 450 460 470
340 350 360 370 380 390
pF1KB9 ACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVV
.:::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::
NP_002 VCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVV
480 490 500 510 520 530
400 410 420 430 440 450
pF1KB9 AVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRK
::::::::::::::::::::::::::::.::::::::::::::::.:::.::::::::::
NP_002 AVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRK
540 550 560 570 580 590
460 470 480 490 500 510
pF1KB9 HQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTL
::::::::::::::::::::::.:::::::::.: ::.:::.:..::.::::.::.: .:
NP_002 HQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSL
600 610 620 630 640 650
520 530 540 550 560 570
pF1KB9 ETKLETLIGSIHALPGLISQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSST
:.::: : .:...:: ::..:.::::.... : .:. :. .. .. :. :::
NP_002 ESKLEHLTASFNSLPLLIADTLRQQQQQLLSAIIEARGVSVAVGTTHTPISDSPIGVSST
660 670 680 690 700 710
pF1KB9 APPTSSESS
. :: ::
NP_002 SFPTPYTSSSSC
720 730
>>XP_005259964 (OMIM: 602982) PREDICTED: small conductan (623 aa)
initn: 2410 init1: 2359 opt: 2359 Z-score: 1576.3 bits: 301.7 E(85289): 4.6e-81
Smith-Waterman score: 2378; 70.7% identity (85.6% similar) in 535 aa overlap (1-533:84-588)
10 20
pF1KB9 MSSCRYNGGVMRPL-SNLSASRRNLHEMDS
:.: :::.: ::: :. .: :. :
XP_005 APQVSAGAQPLSHAGPRAACSEPNPCTQVVMNSHSYNGSVGRPLGSGPGALGRD--PPDP
60 70 80 90 100 110
30 40 50 60 70 80
pF1KB9 EA-QPLQPPASVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGG
:: .: ::: : : . .: . : : ..:. ..:. .....
XP_005 EAGHPPQPPHSPG-----LQVVVAKSEPARPSPGSPR---GQPQDQDDDE----------
120 130 140 150
90 100 110 120 130 140
pF1KB9 STGGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVV
. . . .: . .. : .:.:..::::::::::::::::::::::::::::
XP_005 ----------DDEEDEAGRQRASGKPSNVGHRLGHRRALFEKRKRLSDYALIFGMFGIVV
160 170 180 190 200
150 160 170 180 190 200
pF1KB9 MVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIA
:: :::::::.: : ::::.:::::::::: :::::...:::::::::::::::::::::
XP_005 MVTETELSWGVYTKESLYSFALKCLISLSTAILLGLVVLYHAREIQLFMVDNGADDWRIA
210 220 230 240 250 260
210 220 230 240 250 260
pF1KB9 MTYERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYL
:: ::.:.: ::. ::::::.::.: :::::::::.::::.. ::::..:::::::::::
XP_005 MTCERVFLISLELAVCAIHPVPGHYRFTWTARLAFTYAPSVAEADVDVLLSIPMFLRLYL
270 280 290 300 310 320
270 280 290 300 310 320
pF1KB9 IARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWT
..::::::::.:::::::::::::::.::::::::::::::::::::::::: :::::::
XP_005 LGRVMLLHSKIFTDASSRSIGALNKITFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWT
330 340 350 360 370 380
330 340 350 360 370 380
pF1KB9 VRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTAL
::.::::::.:.::::::::::::::::::::::::::.:::::::::::::::::::::
XP_005 VRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTAL
390 400 410 420 430 440
390 400 410 420 430 440
pF1KB9 VVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKV
:::::::::::::::::::::::::::::::::::::::::::::::.:.:::: :.:.:
XP_005 VVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQARV
450 460 470 480 490 500
450 460 470 480 490 500
pF1KB9 RKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIV
::::::::::::::::::.:: :::::::::.::::::..:::..:.:. . :..: :..
XP_005 RKHQRKFLQAIHQLRSVKIEQGKLNDQANTLTDLAKTQTVMYDLVSELHAQHEELEARLA
510 520 530 540 550 560
510 520 530 540 550 560
pF1KB9 TLETKLETLIGSIHALPGLISQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSS
:::..:..: .:..::::::.:.::
XP_005 TLESRLDALGASLQALPGLIAQAIRPPPPPLPPRPGPGPQDQAARSSPCRWTPVAPSDCG
570 580 590 600 610 620
>>NP_002239 (OMIM: 602982) small conductance calcium-act (543 aa)
initn: 2082 init1: 2031 opt: 2343 Z-score: 1566.5 bits: 299.7 E(85289): 1.6e-80
Smith-Waterman score: 2362; 70.3% identity (85.1% similar) in 538 aa overlap (1-533:1-508)
10 20 30 40 50
pF1KB9 MSSCRYNGGVMRPL-SNLSASRRNLHEMDSEA-QPLQPPASVGGGGGASSPSAAAAAAAA
:.: :::.: ::: :. .: :. : :: .: ::: : : . .: . :
NP_002 MNSHSYNGSVGRPLGSGPGALGRD--PPDPEAGHPPQPPHSPG-----LQVVVAKSEPAR
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 VSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGHGSSSGTKSSKKKNQNIG
: ..:. ..:. ..... . . . .: . .. : .:.:
NP_002 PSPGSPR---GQPQDQDDDE--------------------DDEEDEAGRQRASGKPSNVG
60 70 80 90
120 130 140 150 160 170
pF1KB9 YKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLST
..:::::::::::::::::::::::::::::: :::::::.: : ::::.::::::::::
NP_002 HRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESLYSFALKCLISLST
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB9 IILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWT
:::::...::::::::::::::::::::::: ::.:.: ::. ::::::.::.: ::::
NP_002 AILLGLVVLYHAREIQLFMVDNGADDWRIAMTCERVFLISLELAVCAIHPVPGHYRFTWT
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB9 ARLAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNT
:::::.::::.. ::::..:::::::::::..::::::::.:::::::::::::::.:::
NP_002 ARLAFTYAPSVAEADVDVLLSIPMFLRLYLLGRVMLLHSKIFTDASSRSIGALNKITFNT
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB9 RFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLS
:::::::::::::::::::::: :::::::::.::::::.:.::::::::::::::::::
NP_002 RFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERYHDKQEVTSNFLGAMWLISITFLS
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB9 IGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKR
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKR
340 350 360 370 380 390
420 430 440 450 460 470
pF1KB9 VKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQ---LRSVKMEQRKLNDQ
:::::::::::::::::.:.:::: :.:.:::::::::::::: :::::.:: :::::
NP_002 VKNAAANVLRETWLIYKHTRLVKKPDQARVRKHQRKFLQAIHQAQKLRSVKIEQGKLNDQ
400 410 420 430 440 450
480 490 500 510 520 530
pF1KB9 ANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLISQTIRQQ
::::.::::::..:::..:.:. . :..: :..:::..:..: .:..::::::.:.::
NP_002 ANTLTDLAKTQTVMYDLVSELHAQHEELEARLATLESRLDALGASLQALPGLIAQAIRPP
460 470 480 490 500 510
540 550 560 570
pF1KB9 QRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS
NP_002 PPPLPPRPGPGPQDQAARSSPCRWTPVAPSDCG
520 530 540
>>XP_005259963 (OMIM: 602982) PREDICTED: small conductan (626 aa)
initn: 2082 init1: 2031 opt: 2343 Z-score: 1565.8 bits: 299.8 E(85289): 1.8e-80
Smith-Waterman score: 2362; 70.3% identity (85.1% similar) in 538 aa overlap (1-533:84-591)
10 20
pF1KB9 MSSCRYNGGVMRPL-SNLSASRRNLHEMDS
:.: :::.: ::: :. .: :. :
XP_005 APQVSAGAQPLSHAGPRAACSEPNPCTQVVMNSHSYNGSVGRPLGSGPGALGRD--PPDP
60 70 80 90 100 110
30 40 50 60 70 80
pF1KB9 EA-QPLQPPASVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGG
:: .: ::: : : . .: . : : ..:. ..:. .....
XP_005 EAGHPPQPPHSPG-----LQVVVAKSEPARPSPGSPR---GQPQDQDDDE----------
120 130 140 150
90 100 110 120 130 140
pF1KB9 STGGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVV
. . . .: . .. : .:.:..::::::::::::::::::::::::::::
XP_005 ----------DDEEDEAGRQRASGKPSNVGHRLGHRRALFEKRKRLSDYALIFGMFGIVV
160 170 180 190 200
150 160 170 180 190 200
pF1KB9 MVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIA
:: :::::::.: : ::::.:::::::::: :::::...:::::::::::::::::::::
XP_005 MVTETELSWGVYTKESLYSFALKCLISLSTAILLGLVVLYHAREIQLFMVDNGADDWRIA
210 220 230 240 250 260
210 220 230 240 250 260
pF1KB9 MTYERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYL
:: ::.:.: ::. ::::::.::.: :::::::::.::::.. ::::..:::::::::::
XP_005 MTCERVFLISLELAVCAIHPVPGHYRFTWTARLAFTYAPSVAEADVDVLLSIPMFLRLYL
270 280 290 300 310 320
270 280 290 300 310 320
pF1KB9 IARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWT
..::::::::.:::::::::::::::.::::::::::::::::::::::::: :::::::
XP_005 LGRVMLLHSKIFTDASSRSIGALNKITFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWT
330 340 350 360 370 380
330 340 350 360 370 380
pF1KB9 VRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTAL
::.::::::.:.::::::::::::::::::::::::::.:::::::::::::::::::::
XP_005 VRVCERYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTAL
390 400 410 420 430 440
390 400 410 420 430 440
pF1KB9 VVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKV
:::::::::::::::::::::::::::::::::::::::::::::::.:.:::: :.:.:
XP_005 VVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQARV
450 460 470 480 490 500
450 460 470 480 490 500
pF1KB9 RKHQRKFLQAIHQ---LRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEK
::::::::::::: :::::.:: :::::::::.::::::..:::..:.:. . :..:
XP_005 RKHQRKFLQAIHQAQKLRSVKIEQGKLNDQANTLTDLAKTQTVMYDLVSELHAQHEELEA
510 520 530 540 550 560
510 520 530 540 550 560
pF1KB9 RIVTLETKLETLIGSIHALPGLISQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRR
:..:::..:..: .:..::::::.:.::
XP_005 RLATLESRLDALGASLQALPGLIAQAIRPPPPPLPPRPGPGPQDQAARSSPCRWTPVAPS
570 580 590 600 610 620
>>XP_011526306 (OMIM: 602982) PREDICTED: small conductan (626 aa)
initn: 1327 init1: 1276 opt: 2343 Z-score: 1565.8 bits: 299.8 E(85289): 1.8e-80
Smith-Waterman score: 2362; 70.3% identity (85.1% similar) in 538 aa overlap (1-533:84-591)
10 20
pF1KB9 MSSCRYNGGVMRPL-SNLSASRRNLHEMDS
:.: :::.: ::: :. .: :. :
XP_011 APQVSAGAQPLSHAGPRAACSEPNPCTQVVMNSHSYNGSVGRPLGSGPGALGRD--PPDP
60 70 80 90 100 110
30 40 50 60 70 80
pF1KB9 EA-QPLQPPASVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGG
:: .: ::: : : . .: . : : ..:. ..:. .....
XP_011 EAGHPPQPPHSPG-----LQVVVAKSEPARPSPGSPR---GQPQDQDDDE----------
120 130 140 150
90 100 110 120 130 140
pF1KB9 STGGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVV
. . . .: . .. : .:.:..::::::::::::::::::::::::::::
XP_011 ----------DDEEDEAGRQRASGKPSNVGHRLGHRRALFEKRKRLSDYALIFGMFGIVV
160 170 180 190 200
150 160 170 180 190 200
pF1KB9 MVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIA
:: :::::::.: : ::::.:::::::::: :::::...:::::::::::::::::::::
XP_011 MVTETELSWGVYTKESLYSFALKCLISLSTAILLGLVVLYHAREIQLFMVDNGADDWRIA
210 220 230 240 250 260
210 220 230 240 250 260
pF1KB9 MTYERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYL
:: ::.:.: ::. ::::::.::.: :::::::::.::::.. ::::..:::::::::::
XP_011 MTCERVFLISLELAVCAIHPVPGHYRFTWTARLAFTYAPSVAEADVDVLLSIPMFLRLYL
270 280 290 300 310 320
270 280 290 300 310 320
pF1KB9 IARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWT
..::::::::.:::::::::::::::.::::::::::::::::::::::::: :::::::
XP_011 LGRVMLLHSKIFTDASSRSIGALNKITFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWT
330 340 350 360 370 380
330 340 350 360 370 380
pF1KB9 VRACER---YHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGC
::.::: :::.:.::::::::::::::::::::::::::.::::::::::::::::::
XP_011 VRVCERENMYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGC
390 400 410 420 430 440
390 400 410 420 430 440
pF1KB9 TALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDH
::::::::::::::::::::::::::::::::::::::::::::::::::.:.:::: :.
XP_011 TALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQ
450 460 470 480 490 500
450 460 470 480 490 500
pF1KB9 AKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEK
:.:::::::::::::::::::.:: :::::::::.::::::..:::..:.:. . :..:
XP_011 ARVRKHQRKFLQAIHQLRSVKIEQGKLNDQANTLTDLAKTQTVMYDLVSELHAQHEELEA
510 520 530 540 550 560
510 520 530 540 550 560
pF1KB9 RIVTLETKLETLIGSIHALPGLISQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSSRRR
:..:::..:..: .:..::::::.:.::
XP_011 RLATLESRLDALGASLQALPGLIAQAIRPPPPPLPPRPGPGPQDQAARSSPCRWTPVAPS
570 580 590 600 610 620
>>XP_011526307 (OMIM: 602982) PREDICTED: small conductan (546 aa)
initn: 2107 init1: 1276 opt: 2327 Z-score: 1555.9 bits: 297.7 E(85289): 6.4e-80
Smith-Waterman score: 2346; 69.9% identity (84.7% similar) in 541 aa overlap (1-533:1-511)
10 20 30 40 50
pF1KB9 MSSCRYNGGVMRPL-SNLSASRRNLHEMDSEA-QPLQPPASVGGGGGASSPSAAAAAAAA
:.: :::.: ::: :. .: :. : :: .: ::: : : . .: . :
XP_011 MNSHSYNGSVGRPLGSGPGALGRD--PPDPEAGHPPQPPHSPG-----LQVVVAKSEPAR
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 VSSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGGGSGHGSSSGTKSSKKKNQNIG
: ..:. ..:. ..... . . . .: . .. : .:.:
XP_011 PSPGSPR---GQPQDQDDDE--------------------DDEEDEAGRQRASGKPSNVG
60 70 80 90
120 130 140 150 160 170
pF1KB9 YKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLST
..:::::::::::::::::::::::::::::: :::::::.: : ::::.::::::::::
XP_011 HRLGHRRALFEKRKRLSDYALIFGMFGIVVMVTETELSWGVYTKESLYSFALKCLISLST
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB9 IILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWT
:::::...::::::::::::::::::::::: ::.:.: ::. ::::::.::.: ::::
XP_011 AILLGLVVLYHAREIQLFMVDNGADDWRIAMTCERVFLISLELAVCAIHPVPGHYRFTWT
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB9 ARLAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNT
:::::.::::.. ::::..:::::::::::..::::::::.:::::::::::::::.:::
XP_011 ARLAFTYAPSVAEADVDVLLSIPMFLRLYLLGRVMLLHSKIFTDASSRSIGALNKITFNT
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB9 RFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACER---YHDQQDVTSNFLGAMWLISIT
:::::::::::::::::::::: :::::::::.::: :::.:.:::::::::::::::
XP_011 RFVMKTLMTICPGTVLLVFSISSWIIAAWTVRVCERENMYHDKQEVTSNFLGAMWLISIT
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB9 FLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQL
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQL
340 350 360 370 380 390
420 430 440 450 460 470
pF1KB9 TKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQ---LRSVKMEQRKL
::::::::::::::::::::.:.:::: :.:.:::::::::::::: :::::.:: ::
XP_011 TKRVKNAAANVLRETWLIYKHTRLVKKPDQARVRKHQRKFLQAIHQAQKLRSVKIEQGKL
400 410 420 430 440 450
480 490 500 510 520 530
pF1KB9 NDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLISQTI
:::::::.::::::..:::..:.:. . :..: :..:::..:..: .:..::::::.:.:
XP_011 NDQANTLTDLAKTQTVMYDLVSELHAQHEELEARLATLESRLDALGASLQALPGLIAQAI
460 470 480 490 500 510
540 550 560 570
pF1KB9 RQQQRDFIEAQMESYDKHVTYNAERSRSSSRRRRSSSTAPPTSSESS
:
XP_011 RPPPPPLPPRPGPGPQDQAARSSPCRWTPVAPSDCG
520 530 540
>>XP_005259962 (OMIM: 602982) PREDICTED: small conductan (629 aa)
initn: 2107 init1: 1276 opt: 2327 Z-score: 1555.2 bits: 297.8 E(85289): 6.9e-80
Smith-Waterman score: 2346; 69.9% identity (84.7% similar) in 541 aa overlap (1-533:84-594)
10 20
pF1KB9 MSSCRYNGGVMRPL-SNLSASRRNLHEMDS
:.: :::.: ::: :. .: :. :
XP_005 APQVSAGAQPLSHAGPRAACSEPNPCTQVVMNSHSYNGSVGRPLGSGPGALGRD--PPDP
60 70 80 90 100 110
30 40 50 60 70 80
pF1KB9 EA-QPLQPPASVGGGGGASSPSAAAAAAAAVSSSAPEIVVSKPEHNNSNNLALYGTGGGG
:: .: ::: : : . .: . : : ..:. ..:. .....
XP_005 EAGHPPQPPHSPG-----LQVVVAKSEPARPSPGSPR---GQPQDQDDDE----------
120 130 140 150
90 100 110 120 130 140
pF1KB9 STGGGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVV
. . . .: . .. : .:.:..::::::::::::::::::::::::::::
XP_005 ----------DDEEDEAGRQRASGKPSNVGHRLGHRRALFEKRKRLSDYALIFGMFGIVV
160 170 180 190 200
150 160 170 180 190 200
pF1KB9 MVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIA
:: :::::::.: : ::::.:::::::::: :::::...:::::::::::::::::::::
XP_005 MVTETELSWGVYTKESLYSFALKCLISLSTAILLGLVVLYHAREIQLFMVDNGADDWRIA
210 220 230 240 250 260
210 220 230 240 250 260
pF1KB9 MTYERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYL
:: ::.:.: ::. ::::::.::.: :::::::::.::::.. ::::..:::::::::::
XP_005 MTCERVFLISLELAVCAIHPVPGHYRFTWTARLAFTYAPSVAEADVDVLLSIPMFLRLYL
270 280 290 300 310 320
270 280 290 300 310 320
pF1KB9 IARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWT
..::::::::.:::::::::::::::.::::::::::::::::::::::::: :::::::
XP_005 LGRVMLLHSKIFTDASSRSIGALNKITFNTRFVMKTLMTICPGTVLLVFSISSWIIAAWT
330 340 350 360 370 380
330 340 350 360 370 380
pF1KB9 VRACER---YHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGC
::.::: :::.:.::::::::::::::::::::::::::.::::::::::::::::::
XP_005 VRVCERENMYHDKQEVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGC
390 400 410 420 430 440
390 400 410 420 430 440
pF1KB9 TALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDH
::::::::::::::::::::::::::::::::::::::::::::::::::.:.:::: :.
XP_005 TALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKHTRLVKKPDQ
450 460 470 480 490 500
450 460 470 480 490 500
pF1KB9 AKVRKHQRKFLQAIHQ---LRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSED
:.:::::::::::::: :::::.:: :::::::::.::::::..:::..:.:. . :.
XP_005 ARVRKHQRKFLQAIHQAQKLRSVKIEQGKLNDQANTLTDLAKTQTVMYDLVSELHAQHEE
510 520 530 540 550 560
510 520 530 540 550 560
pF1KB9 FEKRIVTLETKLETLIGSIHALPGLISQTIRQQQRDFIEAQMESYDKHVTYNAERSRSSS
.: :..:::..:..: .:..::::::.:.::
XP_005 LEARLATLESRLDALGASLQALPGLIAQAIRPPPPPLPPRPGPGPQDQAARSSPCRWTPV
570 580 590 600 610 620
570
pF1KB9 RRRRSSSTAPPTSSESS
XP_005 APSDCG
579 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 19:41:02 2016 done: Sun Nov 6 19:41:04 2016
Total Scan time: 10.640 Total Display time: 0.110
Function used was FASTA [36.3.4 Apr, 2011]