Result of FASTA (omim) for
pFN21AE2470
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE2470, 474 aa
1>>>pF1KE2470 474 - 474 aa - 474 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.6311+/-0.000413; mu= 2.6342+/- 0.026
mean_var=407.7304+/-83.553, 0's: 0 Z-trim(123.3): 99 B-trim: 83 in 1/58
Lambda= 0.063517
statistics sampled from 42783 (42895) to 42783 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.779), E-opt: 0.2 (0.503), width: 16
Scan time: 12.280
The best scores are: opt bits E(85289)
NP_003098 (OMIM: 184430) transcription factor SOX- ( 474) 3123 300.1 8.8e-81
NP_003099 (OMIM: 600898,615866) transcription fact ( 441) 718 79.7 1.8e-14
NP_008874 (OMIM: 601947) transcription factor SOX- ( 315) 647 73.0 1.4e-12
NP_005977 (OMIM: 602148) transcription factor SOX- ( 391) 486 58.3 4.3e-08
NP_009015 (OMIM: 604974) transcription factor SOX- ( 276) 456 55.4 2.3e-07
NP_055402 (OMIM: 605923) transcription factor SOX- ( 446) 442 54.4 7.6e-07
NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapi ( 233) 426 52.6 1.4e-06
NP_005625 (OMIM: 300123,312000,313430) transcripti ( 446) 420 52.4 3.1e-06
NP_003097 (OMIM: 184429,189960,206900) transcripti ( 317) 402 50.5 7.9e-06
NP_008872 (OMIM: 602229,609136,611584,613266) tran ( 466) 405 51.0 8.2e-06
NP_004180 (OMIM: 604747) transcription factor SOX- ( 240) 394 49.6 1.1e-05
NP_000337 (OMIM: 114290,608160,616425) transcripti ( 509) 387 49.4 2.7e-05
NP_071899 (OMIM: 610928,613674) transcription fact ( 414) 376 48.3 4.8e-05
NP_060889 (OMIM: 137940,601618,607823) transcripti ( 384) 369 47.6 7.2e-05
NP_113627 (OMIM: 612202) transcription factor SOX- ( 388) 369 47.6 7.2e-05
NP_821078 (OMIM: 604975,616803) transcription fact ( 377) 343 45.2 0.00037
XP_011519144 (OMIM: 604975,616803) PREDICTED: tran ( 415) 343 45.3 0.00039
NP_001248343 (OMIM: 604975,616803) transcription f ( 642) 343 45.5 0.00051
XP_016875389 (OMIM: 604975,616803) PREDICTED: tran ( 715) 343 45.6 0.00055
XP_016875388 (OMIM: 604975,616803) PREDICTED: tran ( 715) 343 45.6 0.00055
XP_016875390 (OMIM: 604975,616803) PREDICTED: tran ( 715) 343 45.6 0.00055
XP_016875387 (OMIM: 604975,616803) PREDICTED: tran ( 715) 343 45.6 0.00055
XP_016875386 (OMIM: 604975,616803) PREDICTED: tran ( 716) 343 45.6 0.00055
NP_001317714 (OMIM: 604975,616803) transcription f ( 728) 343 45.6 0.00055
XP_011519140 (OMIM: 604975,616803) PREDICTED: tran ( 729) 343 45.6 0.00055
XP_016875385 (OMIM: 604975,616803) PREDICTED: tran ( 750) 343 45.6 0.00056
NP_694534 (OMIM: 604975,616803) transcription fact ( 750) 343 45.6 0.00056
XP_016875384 (OMIM: 604975,616803) PREDICTED: tran ( 751) 343 45.6 0.00056
XP_016875380 (OMIM: 604975,616803) PREDICTED: tran ( 751) 343 45.6 0.00056
XP_016875379 (OMIM: 604975,616803) PREDICTED: tran ( 751) 343 45.6 0.00056
XP_011519137 (OMIM: 604975,616803) PREDICTED: tran ( 751) 343 45.6 0.00056
XP_016875382 (OMIM: 604975,616803) PREDICTED: tran ( 751) 343 45.6 0.00056
XP_016875381 (OMIM: 604975,616803) PREDICTED: tran ( 751) 343 45.6 0.00056
XP_011519139 (OMIM: 604975,616803) PREDICTED: tran ( 751) 343 45.6 0.00056
XP_016875383 (OMIM: 604975,616803) PREDICTED: tran ( 751) 343 45.6 0.00056
XP_011519136 (OMIM: 604975,616803) PREDICTED: tran ( 751) 343 45.6 0.00056
NP_001248344 (OMIM: 604975,616803) transcription f ( 753) 343 45.6 0.00057
XP_011519135 (OMIM: 604975,616803) PREDICTED: tran ( 754) 343 45.6 0.00057
NP_008871 (OMIM: 604975,616803) transcription fact ( 763) 343 45.6 0.00057
XP_011519134 (OMIM: 604975,616803) PREDICTED: tran ( 764) 343 45.6 0.00057
XP_016875378 (OMIM: 604975,616803) PREDICTED: tran ( 792) 343 45.6 0.00058
XP_016875377 (OMIM: 604975,616803) PREDICTED: tran ( 793) 343 45.6 0.00058
NP_201583 (OMIM: 607257) transcription factor SOX- ( 808) 343 45.7 0.00059
XP_005245680 (OMIM: 604748) PREDICTED: transcripti ( 621) 340 45.2 0.00061
NP_005677 (OMIM: 604748) transcription factor SOX- ( 622) 340 45.2 0.00061
NP_001139283 (OMIM: 607257) transcription factor S ( 801) 339 45.3 0.00076
NP_059978 (OMIM: 607257) transcription factor SOX- ( 804) 339 45.3 0.00076
NP_001139291 (OMIM: 607257) transcription factor S ( 841) 339 45.3 0.00078
NP_003131 (OMIM: 400044,400045,480000) sex-determi ( 204) 321 42.9 0.001
>>NP_003098 (OMIM: 184430) transcription factor SOX-4 [H (474 aa)
initn: 3123 init1: 3123 opt: 3123 Z-score: 1571.3 bits: 300.1 E(85289): 8.8e-81
Smith-Waterman score: 3123; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KE2 MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE2 RPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE2 ADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE2 GGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE2 QAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE2 GLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 GLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE2 YASLRAASPAPSSAPSHASSSASSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFESMSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YASLRAASPAPSSAPSHASSSASSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFESMSLG
370 380 390 400 410 420
430 440 450 460 470
pF1KE2 SFSSSSALDRDLDFNFEPGSGSHFEFPDYCTPEVSEMISGDWLESSISNLVFTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SFSSSSALDRDLDFNFEPGSGSHFEFPDYCTPEVSEMISGDWLESSISNLVFTY
430 440 450 460 470
>>NP_003099 (OMIM: 600898,615866) transcription factor S (441 aa)
initn: 1098 init1: 628 opt: 718 Z-score: 380.6 bits: 79.7 E(85289): 1.8e-14
Smith-Waterman score: 1010; 43.3% identity (64.9% similar) in 490 aa overlap (1-474:1-441)
10 20 30 40 50 60
pF1KE2 MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIK
::::... : .:. : :. :. : :. .: ::. . . ::.:::: :::::
NP_003 MVQQAESLE-AESNLPREALDTEEG-EF-MACSPVALDES-------DPDWCKTASGHIK
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 RPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHM
::::::::::.:::::::::::::::::::::::::::.::::.::::::::::::::::
NP_003 RPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 ADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGG
::::::::::::: : . :.. .::..: .: ...:::: .:::.::.... :.
NP_003 ADYPDYKYRPRKKPK---MDPSAKPSASQSP----EKSAAGGGGGSAGGGAGGAKTSKGS
120 130 140 150 160
190 200 210 220 230
pF1KE2 GGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHA--KLILAGGGGGGKAAAAAAASFA
. . : . . : . :. . .: ::.. .. .: ..:.:::: :. .. :
NP_003 SKKCGKLKAPAAAGAKAGAGKAAQSGDYGGAGDDYVLGSLRVSGSGGGG-AGKTVKCVFL
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE2 AEQAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYL
:. :. .: . :. . . : ::.. ... : :
NP_003 DEDDDD------DDDDDELQLQIKQEPD---EEDEEPPHQQLLQPPGQQ--PSQLLRRYN
230 240 250 260 270
300 310 320 330 340 350
pF1KE2 FGGLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADH
. . .::. ....:. . .::.: :: :.: :.: : .
NP_003 VAKV--PASPT--LSSSAESPEGASLYDEVRAG--------------ATSGAGGGSRL-Y
280 290 300 310
360 370 380 390 400 410
pF1KE2 RGYASLRAASPAPSSAP--SHASSSASSHSSSSSSSGSSSSDDEFEDDL---LDLNPSSN
.. .. : : . : : ::: . : ::::::..::.:. : ::: :.:: :..
NP_003 YSFKNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSGEDADDLMFDLSLNFSQS
320 330 340 350 360 370
420 430 440 450 460
pF1KE2 FESMS---LGSFSSSSAL-----DRDLDFNFEPGS-GSHFEFPDYCTPEVSEMISGDWLE
.: : ::. .... : :.::: .: :: :::::::::::::.::::.:::::
NP_003 AHSASEQQLGGGAAAGNLSLSLVDKDLD-SFSEGSLGSHFEFPDYCTPELSEMIAGDWLE
380 390 400 410 420 430
470
pF1KE2 SSISNLVFTY
...:.:::::
NP_003 ANFSDLVFTY
440
>>NP_008874 (OMIM: 601947) transcription factor SOX-12 [ (315 aa)
initn: 862 init1: 580 opt: 647 Z-score: 347.0 bits: 73.0 E(85289): 1.4e-12
Smith-Waterman score: 679; 38.5% identity (50.2% similar) in 442 aa overlap (34-474:16-315)
10 20 30 40 50 60
pF1KE2 QTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIKRPM
: :: . : : .:.:::::::::::::
NP_008 MVQQRGARAKRDGGPPPPGPGPAEEG-AREPGWCKTPSGHIKRPM
10 20 30 40
70 80 90 100 110 120
pF1KE2 NAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADY
:::::::: ::::::.: :::::::::::::.::.::.::.::::.::::::::::::::
NP_008 NAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRLKHMADY
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE2 PDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGG
:::::::::: :..: :...: :
NP_008 PDYKYRPRKK--------SKGAPAKARPRPPG----------------------------
110 120
190 200 210 220 230 240
pF1KE2 ASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAEQAG
.::::. :: : .. : :: . ::: :: ::: .
NP_008 GSGGGSRLKP------GPQLPG-RGGRRA--------AGGPLGGGAAAPEDDD-------
130 140 150 160
250 260 270 280 290 300
pF1KE2 AAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGLG
: . : ..: . .::..: :.
NP_008 ---------EDDDEELLEVRL----------------VETPGREL-----WRMV------
170 180 190
310 320 330 340 350 360
pF1KE2 TSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGYAS
:.: .. : :.. : :: : ..::
NP_008 ----PAGRAARGQ---------AERAQG-----PSGEGAAAAA-----------------
200 210
370 380 390 400 410 420
pF1KE2 LRAASPAPSSAPSHASSSASSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFESMSLGSFS
::::.:: . .. . . .: .: : : :. .:
NP_008 --AASPTPSEDEEPEEEEEEAAAAEEGEEETVASGEESLGFLSRLPPGPA----GL----
220 230 240 250 260
430 440 450 460 470
pF1KE2 SSSALDRDLDFNFEPGSG-SHFEFPDYCTPEVSEMISGDWLESSISNLVFTY
. :::::: : ..: :: :::::::::::::.:::.::: :::..:::::
NP_008 DCSALDRDPD--LQPPSGTSHFEFPDYCTPEVTEMIAGDWRPSSIADLVFTY
270 280 290 300 310
>>NP_005977 (OMIM: 602148) transcription factor SOX-1 [H (391 aa)
initn: 413 init1: 413 opt: 486 Z-score: 266.3 bits: 58.3 E(85289): 4.3e-08
Smith-Waterman score: 506; 33.9% identity (57.9% similar) in 363 aa overlap (20-378:12-332)
10 20 30 40 50 60
pF1KE2 MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIK
: .:: .... :. .. :: . . :. . ..:
NP_005 MYSMMMETDLHSPGGAQAPTNLSGPAGAGGGGGGGGGGGGGGGAKANQDRVK
10 20 30 40 50
70 80 90 100 110 120
pF1KE2 RPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHM
::::::::::. .:::. ...: :::.::::::: .::......: ::: ::.::: ::
NP_005 RPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKVMSEAEKRPFIDEAKRLRALHM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE2 ADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGG
..::::::::.:.:. : :: . .:: .:.::::.. : :
NP_005 KEHPDYKYRPRRKTKTL---------------LKKDKYSLAGGLLAAGAGGGGAAVAMGV
120 130 140 150
190 200 210 220 230 240
pF1KE2 GGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAE
: :. :: . . .: : :.:::: . :.. :. :. :::::::.. :
NP_005 GVGV---GAAAVGQRLESPG----GAAGGGYA--HVNGWANGAYPGSVAAAAAAAAMMQE
160 170 180 190 200
250 260 270 280 290 300
pF1KE2 QAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFG
: : : .: :.:... : : : : . . . : .:
NP_005 -----AQLAYG----QH-------PGAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYDMG
210 220 230 240 250
310 320 330 340 350
pF1KE2 GLGTSSSPVGGVGA--GADPSDPLGL-YEEEGAGCSPDAPSLSGRSSAASSPAAGRSPAD
.: . ::... . .:.:: :: : .:. . . . .. . ::.. ::. : .
NP_005 AL--QYSPISNSQGYMSASPSGYGGLPYGAAAAAAAAAGGAHQNSAVAAAAAAAAASSGA
260 270 280 290 300 310
360 370 380 390 400 410
pF1KE2 HRGYASLRAASPAPSS-APSHASSSASSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFES
. .:: . :. : ::.:.
NP_005 LGALGSLVKSEPSGSPPAPAHSRAPCPGDLREMISMYLPAGEGGDPAAAAAAAAQSRLHS
320 330 340 350 360 370
>>NP_009015 (OMIM: 604974) transcription factor SOX-21 [ (276 aa)
initn: 505 init1: 393 opt: 456 Z-score: 253.1 bits: 55.4 E(85289): 2.3e-07
Smith-Waterman score: 464; 40.2% identity (65.2% similar) in 244 aa overlap (55-287:4-222)
30 40 50 60 70 80
pF1KE2 GLELGIASSPTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDM
: :.:::::::::::. .:::. ...: :
NP_009 MSKPVDHVKRPMNAFMVWSRAQRRKMAQENPKM
10 20 30
90 100 110 120 130 140
pF1KE2 HNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSGNANSSSS
::.::::::: .:::: .:.: ::: ::.::: :: ..::::::::.: :. ... .
NP_009 HNSEISKRLGAEWKLLTESEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKTLLKKDKFA
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE2 AAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVA
: : .:: . . : . .:.. .::.::: . : . . :.:
NP_009 F-----PVPYG--LGGVADAEHPALKAGAGLHAGAGGGLV--------PESLLANPEKAA
100 110 120 130
210 220 230 240 250
pF1KE2 GGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAEQAGAA-ALLPLGA-----AADHHS
..:.... :.... ..::::::. :: ::. .:: ::. ... .
NP_009 AAAAAAA----ARVFFP------QSAAAAAAAAAAAAAGSPYSLLDLGSKMAEISSSSSG
140 150 160 170 180
260 270 280 290 300 310
pF1KE2 LYKART---PSASASA--SSAASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVG
: : . :.:.:.: ..::.:.:: :: : :
NP_009 LPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNPGYMIPCNCSAWPSPGL
190 200 210 220 230 240
320 330 340 350 360 370
pF1KE2 AGADPSDPLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGYASLRAASPAPSS
NP_009 QPPLAYILLPGMGKPQLDPYPAAYAAAL
250 260 270
>>NP_055402 (OMIM: 605923) transcription factor SOX-8 [H (446 aa)
initn: 500 init1: 403 opt: 442 Z-score: 243.9 bits: 54.4 E(85289): 7.6e-07
Smith-Waterman score: 448; 34.7% identity (57.4% similar) in 329 aa overlap (58-375:101-400)
30 40 50 60 70 80
pF1KE2 LGIASSPTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNA
:.::::::::::.: :::. .: : .:::
NP_055 AVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNA
80 90 100 110 120 130
90 100 110 120 130 140
pF1KE2 EISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSGNANSSSSAAA
:.:: ::: :.::..:.: ::..::::::..: :.:::::.::.. ::..:. :
NP_055 ELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRR-KSAKAGHS-----
140 150 160 170 180
150 160 170 180 190 200
pF1KE2 SSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGG--GANSKPAQKKSCGSKVAG
:. .:. : : :::. ...:: : : : : . : . .
NP_055 --------DSDSGAELGPHPGGGAVYKAEAGLGDGHHHGDHTGQTHGPPTPPTTPKTELQ
190 200 210 220 230
210 220 230 240 250 260
pF1KE2 GAGGGVSKPHAKL----ILAGGGGGGKAAAAAAASFAAEQAGAAALLPLGAAADHHSLYK
:: .::. :: . .: . . . . ...: :. . . :..
NP_055 QAG---AKPELKLEGRRPVDSGRQNIDFSNVDISELSSEVMGTMDAFDVHEF-DQYLPLG
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE2 ARTPSASASASSAASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVGAGADPSDP
. .: ..: ..: :. :.: :.:.. . .. : ..: .:: :
NP_055 GPAPPEPGQAYGGAYFHAG-ASPV--WAHKSAPSA---SASPTETGPPRPHIKTEQPS-P
300 310 320 330 340
330 340 350 360 370
pF1KE2 LGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSP-ADHRG-YASLRAAS---PAPSSAPS
: : .. : ::: : ::.::: .::: .: : .: :..:.:.: :. ::
NP_055 -GHYGDQPRG-SPDYGSCSGQSSA--TPAAPAGPFAGSQGDYGDLQASSYYGAYPGYAPG
350 360 370 380 390 400
380 390 400 410 420 430
pF1KE2 HASSSASSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFESMSLGSFSSSSALDRDLDFNF
NP_055 LYQYPCFHSPRRPYASPLLNGLALPPAHSPTSHWDQPVYTTLTRP
410 420 430 440
>>NP_008873 (OMIM: 601297) protein SOX-15 [Homo sapiens] (233 aa)
initn: 446 init1: 396 opt: 426 Z-score: 239.0 bits: 52.6 E(85289): 1.4e-06
Smith-Waterman score: 433; 43.4% identity (69.9% similar) in 173 aa overlap (15-182:3-162)
10 20 30 40 50
pF1KE2 MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGK----ADDPSWCKT-P
: : :.:.. .:: : : ....:.: . : .:. : :
NP_008 MALPGSSQDQAWSLEPPAA---TAAASSSSGPQEREGAGSPAAPGTLP
10 20 30 40
60 70 80 90 100 110
pF1KE2 SGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERL
..:::::::::::. .::.. .:.: :::.::::::: .:::: ...: ::..::.::
NP_008 LEKVKRPMNAFMVWSSAQRRQMAQQNPKMHNSEISKRLGAQWKLLDEDEKRPFVEEAKRL
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 RLKHMADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSS
: .:. ::::::::::.:.::..:. :.. :. :. ..:: : : ...
NP_008 RARHLRDYPDYKYRPRRKAKSSGAG----------PSRCGQGRGNLASGGPLWGPGYATT
110 120 130 140 150
180 190 200 210 220 230
pF1KE2 NAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAA
. . : :
NP_008 QPSRGFGYRPPSYSTAYLPGSYGSSHCKLEAPSPCSLPQSDPRLQGELLPTYTHYLPPGS
160 170 180 190 200 210
>>NP_005625 (OMIM: 300123,312000,313430) transcription f (446 aa)
initn: 379 init1: 379 opt: 420 Z-score: 233.0 bits: 52.4 E(85289): 3.1e-06
Smith-Waterman score: 445; 31.3% identity (55.8% similar) in 380 aa overlap (16-375:106-442)
10 20 30 40
pF1KE2 MVQQTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGK
::.:: ..:: : :. .. :: ::
NP_005 MYSLLETELKNPVGTPTQAAGTGGPAAPGGAGKSSANAAG---GANSGGGSSGGASGGGG
80 90 100 110 120 130
50 60 70 80 90 100
pF1KE2 ADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDK
. : . ..:::::::::::. .:::. ..: :::.::::::: :::: :..:
NP_005 GTDQD-------RVKRPMNAFMVWSRGQRRKMALENPKMHNSEISKRLGADWKLLTDAEK
140 150 160 170 180
110 120 130 140 150 160
pF1KE2 IPFIREAERLRLKHMADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGG
::: ::.::: :: .:::::::::.:.:. : :: . .:
NP_005 RPFIDEAKRLRAVHMKEYPDYKYRPRRKTKTL---------------LKKDKYSLPSGLL
190 200 210 220 230
170 180 190 200 210 220
pF1KE2 HGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGG
:....... :.......: :.. :. . ..: : :.:. : . .: : .
NP_005 PPGAAAAAAAAAAAAAAASSPVGVG----QRLDTYTHVNGWANGAYSLVQEQLGYAQPPS
240 250 260 270 280
230 240 250 260 270
pF1KE2 GGKAAAAAAA------SFAAEQ------AGAAALLPLGAAADHHSLYKARTPSASASASS
.. : ..:. : :: . . ..::: : : . .:::.:.:..
NP_005 MSSPPPPPALPPMHRYDMAGLQYSPMMPPGAQSYMNVAAAAAAASGYGGMAPSATAAAAA
290 300 310 320 330 340
280 290 300 310 320 330
pF1KE2 AASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCS
: . . : :: . : . : .:.:.: . : : .. . .:
NP_005 AYGQQPATAAAAAAAAA------------AMSLGPMGSVVKSEPSSPPPAIASHSQRACL
350 360 370 380 390
340 350 360 370 380
pF1KE2 PDAPSL-------SGRSSAASSP-AAGRSPADHRGYASLRAASPAPSSAPSHASSSASSH
: .. .: .. :.:: .:: . :. : . :.. . ...:
NP_005 GDLRDMISMYLPPGGDAADAASPLPGGRLHGVHQHYQG--AGTAVNGTVPLTHI
400 410 420 430 440
390 400 410 420 430 440
pF1KE2 SSSSSSSGSSSSDDEFEDDLLDLNPSSNFESMSLGSFSSSSALDRDLDFNFEPGSGSHFE
>>NP_003097 (OMIM: 184429,189960,206900) transcription f (317 aa)
initn: 369 init1: 369 opt: 402 Z-score: 225.7 bits: 50.5 E(85289): 7.9e-06
Smith-Waterman score: 428; 32.3% identity (56.0% similar) in 325 aa overlap (34-352:12-305)
10 20 30 40 50
pF1KE2 QTNNAENTEALLAGESSDSGAGLELGIASSPTPGSTASTGGKADDPSWC----KTPSGHI
: : .:.. :: . . :. ..
NP_003 MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRV
10 20 30 40
60 70 80 90 100 110
pF1KE2 KRPMNAFMVWSQIERRKIMEQSPDMHNAEISKRLGKRWKLLKDSDKIPFIREAERLRLKH
:::::::::::. .:::. ...: :::.::::::: .::::....: ::: ::.::: :
NP_003 KRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALH
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE2 MADYPDYKYRPRKKVKSGNANSSSSAAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGG
: ..::::::::.:.:. : :: : : . ::.: :.:
NP_003 MKEHPDYKYRPRRKTKT---------------LMKKDKYTLPG----GLLAPGGNSMASG
110 120 130 140
180 190 200 210 220 230
pF1KE2 GGGGAS-GGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFA
: ::. :.:.: :. . ... : ..:. : . .: : : .::..
NP_003 VGVGAGLGAGVN----QRMDSYAHMNGWSNGSYSMMQDQLGYPQHPG---LNAHGAAQMQ
150 160 170 180 190
240 250 260 270 280 290
pF1KE2 AEQAGAAALLPLGAAADHHSLYKARTPSASASASSAASASAALAAPGKHLAEKKVKRVYL
. .. : .. .. .. : .:. : : :. .. . ::.. :. . . . .
NP_003 PMHRYDVSALQYNSMTSSQT-YMNGSPTYSMSYSQQGTPGMALGSMGSVVKSEASSSPPV
200 210 220 230 240 250
300 310 320 330 340 350
pF1KE2 FGGLGTSSSPVGGVGAGADPSDPLGLYEEEGAGCSPDAPS-LSGRSSAASSPAAGRSPAD
. . : .: :: : : ...: . : ::: : . :.:. :
NP_003 VTSSSHSRAPC---QAG-DLRDMISMYLPGAEVPEPAAPSRLHMSQHYQSGPVPGTAING
260 270 280 290 300 310
360 370 380 390 400 410
pF1KE2 HRGYASLRAASPAPSSAPSHASSSASSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFESM
NP_003 TLPLSHM
>>NP_008872 (OMIM: 602229,609136,611584,613266) transcri (466 aa)
initn: 369 init1: 369 opt: 405 Z-score: 225.3 bits: 51.0 E(85289): 8.2e-06
Smith-Waterman score: 435; 32.1% identity (54.8% similar) in 361 aa overlap (58-392:103-451)
30 40 50 60 70 80
pF1KE2 LGIASSPTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNA
:.::::::::::.: :::. .: : .:::
NP_008 REAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVWAQAARRKLADQYPHLHNA
80 90 100 110 120 130
90 100 110 120 130 140
pF1KE2 EISKRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRKKVKSGNANSSSSAAA
:.:: ::: :.::..::: :::.::::::..: :.:::::.::.. :.:.: .. .
NP_008 ELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRR-KNGKAAQGEAEC-
140 150 160 170 180 190
150 160 170 180 190
pF1KE2 SSKPGEKGDKVGGSGGGGHGGGG-------GGGSSNAGGGGGGASGG--GANSKPAQKKS
:: .... : .. .: .. : :: . :. :: : . :. :.
NP_008 ---PGGEAEQGGTAAIQAHYKSAHLDHRHPGEGSPMSDGNPEHPSGQSHGPPTPPTTPKT
200 210 220 230 240
200 210 220 230 240 250
pF1KE2 ---CGS---KVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAEQAGAAALLPLGA
:. : : . : .::: . . : .. . . .: . : :: ..
NP_008 ELQSGKADPKRDGRSMGEGGKPHIDFGNVDIGEISHEVMSNMETF--DVAELDQYLPPNG
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE2 AADHHSLYKARTPSASASASSAASASAALAAP-GKHLAEKKVKRVYLFGGLGT-SSSPVG
: : :.: . ... . :.. :: .. : : : . : . . : ...: :
NP_008 HPGHVSSYSAAGYGLGSALAVASGHSAWISKPPGVALPTVSPPGVDAKAQVKTETAGPQG
310 320 330 340 350 360
320 330 340 350 360
pF1KE2 GVGAGADPSDP------LGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGYAS-
.:: :.: . .: : . :... . :.: : : : ::
NP_008 PPHYTDQPSTSQIAYTSLSLPHYGSAFPSISRPQFDYSDHQPSGPYYG-----HSGQASG
370 380 390 400 410 420
370 380 390 400 410 420
pF1KE2 LRAASP--APSSAPSHASSSASSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFESMSLGS
: .: .::. : ... : : :. .: :
NP_008 LYSAFSYMGPSQRPLYTAISDPSPSGPQSHSPTHWEQPVYTTLSRP
430 440 450 460
430 440 450 460 470
pF1KE2 FSSSSALDRDLDFNFEPGSGSHFEFPDYCTPEVSEMISGDWLESSISNLVFTY
474 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 20:29:48 2016 done: Mon Nov 7 20:29:49 2016
Total Scan time: 12.280 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]