Result of FASTA (omim) for
pFN21AB8659
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8659, 658 aa
1>>>pF1KB8659 658 - 658 aa - 658 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8444+/-0.000378; mu= 7.7564+/- 0.023
mean_var=148.1067+/-30.209, 0's: 0 Z-trim(117.7): 17 B-trim: 789 in 2/51
Lambda= 0.105387
statistics sampled from 29947 (29961) to 29947 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.351), width: 16
Scan time: 11.590
The best scores are: opt bits E(85289)
NP_060855 (OMIM: 610780) large subunit GTPase 1 ho ( 658) 4464 690.9 4e-198
XP_016862285 (OMIM: 610780) PREDICTED: large subun ( 500) 3289 512.1 1.9e-144
NP_005266 (OMIM: 143024) guanine nucleotide-bindin ( 607) 426 76.9 2.4e-13
XP_005249072 (OMIM: 143024) PREDICTED: guanine nuc ( 607) 426 76.9 2.4e-13
NP_001310553 (OMIM: 609365) nucleolar GTP-binding ( 548) 246 49.5 3.9e-05
NP_037417 (OMIM: 609365) nucleolar GTP-binding pro ( 731) 246 49.6 4.9e-05
NP_001310552 (OMIM: 609365) nucleolar GTP-binding ( 799) 230 47.2 0.00028
NP_001171748 (OMIM: 300873) guanine nucleotide-bin ( 582) 194 41.6 0.0097
NP_061940 (OMIM: 300873) guanine nucleotide-bindin ( 582) 194 41.6 0.0097
>>NP_060855 (OMIM: 610780) large subunit GTPase 1 homolo (658 aa)
initn: 4464 init1: 4464 opt: 4464 Z-score: 3678.0 bits: 690.9 E(85289): 4e-198
Smith-Waterman score: 4464; 99.8% identity (100.0% similar) in 658 aa overlap (1-658:1-658)
10 20 30 40 50 60
pF1KB8 MGRRRAPAGGSLGRALMRHQTQRSRSHRHTDSWLHTSELNDGYDWGRLNLQSVTEQSSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MGRRRAPAGGSLGRALMRHQTQRSRSHRHTDSWLHTSELNDGYDWGRLNLQSVTEQSSLD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 DFLATAELAGTEFVAEKLNIKFVPAEARTGLLSFEESQRIKKLHEENKQFLCIPRRPNWN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DFLATAELAGTEFVAEKLNIKFVPAEARTGLLSFEESQRIKKLHEENKQFLCIPRRPNWN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 QNTTPEELKQAEKDNFLEWRRQLVRLEEEQKLILTPFERNLDFWRQLWRVIERSDIVVQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QNTTPEELKQAEKDNFLEWRRQLVRLEEEQKLILTPFERNLDFWRQLWRVIERSDIVVQI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VDARNPLLFRCEDLECYVKEMDANKENVILINKADLLTAEQRSAWAMYFEKEDVKVIFWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VDARNPLLFRCEDLECYVKEMDANKENVILINKADLLTAEQRSAWAMYFEKEDVKVIFWS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ALAGAIPLNGDSEEEANRDDRQSNTTEFGHSSFDQAEISHSESEHLPARDSPSLSENPTT
::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::
NP_060 ALAGAIPLNGDSEEEANRDDRQSNTTKFGHSSFDQAEISHSESEHLPARDSPSLSENPTT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 DEDDSEYEDCPEEEEDDWQTCSEEDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DEDDSEYEDCPEEEEDDWQTCSEEDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 TKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 HVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKDYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 HVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKDYV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 SGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQE
550 560 570 580 590 600
610 620 630 640 650
pF1KB8 NVRALTKGVQAVMGYKPGSGVVTASTASSENGAGKPWKKHGNRNKKEKSRRLYKHLDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 NVRALTKGVQAVMGYKPGSGVVTASTASSENGAGKPWKKHGNRNKKEKSRRLYKHLDM
610 620 630 640 650
>>XP_016862285 (OMIM: 610780) PREDICTED: large subunit G (500 aa)
initn: 3289 init1: 3289 opt: 3289 Z-score: 2714.3 bits: 512.1 E(85289): 1.9e-144
Smith-Waterman score: 3289; 99.6% identity (100.0% similar) in 485 aa overlap (174-658:16-500)
150 160 170 180 190 200
pF1KB8 VRLEEEQKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEMDA
.:::::::::::::::::::::::::::::
XP_016 MEEVGLAIPASAGQPNDIVVQIVDARNPLLFRCEDLECYVKEMDA
10 20 30 40
210 220 230 240 250 260
pF1KB8 NKENVILINKADLLTAEQRSAWAMYFEKEDVKVIFWSALAGAIPLNGDSEEEANRDDRQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKENVILINKADLLTAEQRSAWAMYFEKEDVKVIFWSALAGAIPLNGDSEEEANRDDRQS
50 60 70 80 90 100
270 280 290 300 310 320
pF1KB8 NTTEFGHSSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPEEEEDDWQTCSE
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NTTKFGHSSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPEEEEDDWQTCSE
110 120 130 140 150 160
330 340 350 360 370 380
pF1KB8 EDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVK
170 180 190 200 210 220
390 400 410 420 430 440
pF1KB8 DGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVM
230 240 250 260 270 280
450 460 470 480 490 500
pF1KB8 PSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRP
290 300 310 320 330 340
510 520 530 540 550 560
pF1KB8 PTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKDYVSGKLLYCHPPPGRDPVTFQHQHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKDYVSGKLLYCHPPPGRDPVTFQHQHQ
350 360 370 380 390 400
570 580 590 600 610 620
pF1KB8 RLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVMGYKPGSGVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVMGYKPGSGVVT
410 420 430 440 450 460
630 640 650
pF1KB8 ASTASSENGAGKPWKKHGNRNKKEKSRRLYKHLDM
:::::::::::::::::::::::::::::::::::
XP_016 ASTASSENGAGKPWKKHGNRNKKEKSRRLYKHLDM
470 480 490 500
>>NP_005266 (OMIM: 143024) guanine nucleotide-binding pr (607 aa)
initn: 560 init1: 302 opt: 426 Z-score: 360.5 bits: 76.9 E(85289): 2.4e-13
Smith-Waterman score: 602; 31.0% identity (55.2% similar) in 449 aa overlap (111-552:127-522)
90 100 110 120 130 140
pF1KB8 KFVPAEARTGLLSFEESQRIKKLHEENKQFLCIPRRPNWNQNTTPEELKQAEKDNFLEWR
: .:::: :. . . :.: . :. .: ..
NP_005 KRAAREQVLQPVSAELLELDIREVYQPGSVLDFPRRPPWSYEMSKEQLMSQEERSFQDYL
100 110 120 130 140 150
150 160 170 180 190 200
pF1KB8 RQLVRLEEEQKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKE
.. .:: . ::.::. :::::::.: ::::. :.: :.:.. : ::
NP_005 GKIHGAYSSEKL--SYFEHNLETWRQLWRVLEMSDIVLLITDIRHPVVNFPPALYEYVTG
160 170 180 190 200 210
210 220 230 240 250
pF1KB8 MDANKENVILINKADLLTAEQRSAWAMYFEKE--DVKVIFWSALA--GAIPLNGDSEEEA
. . :...::.:: :: ::... ...:...... : . .: .
NP_005 -ELGLALVLVLNKVDLAPPALVVAWKHYFHQHYPQLHVVLFTSFPRDPRTPQDPSSVLKK
220 230 240 250 260 270
260 270 280 290 300 310
pF1KB8 NRDDRQSNTTEFGHSSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPEEEED
.: .. : .: .. .: :. . : : :. . : . . . :::.
NP_005 SRRRGRGWTRALGPEQLLRA----CEAITVGKVDLSSWREKIARDVAGATWGNGSGEEEE
280 290 300 310 320
320 330 340 350 360 370
pF1KB8 DWQTCSEEDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKEL
::::: . :: .: .
NP_005 ------EEDGP---------------------------------AVLVEQQTDSAMEPTG
330 340 350
380 390 400 410 420 430
pF1KB8 HTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLC
: .. ::: .:.: ::.::::::: :: ..: : :::: :::::..::: .. :.. ::
NP_005 PTQERYKDGVVTIGCVGFPNVGKSSLINGLVGRKVVSVSRTPGHTRYFQTYFLTPSVKLC
360 370 380 390 400 410
440 450 460 470 480 490
pF1KB8 DCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPRE
:::::..::.. . .. .:: :: :... :. . . :: ..: ... : :
NP_005 DCPGLIFPSLLPRQLQVL-AGIYPIAQIQEPYTAVGYLASRIPVQAL-----LHLRHP-E
420 430 440 450 460
500 510 520 530 540 550
pF1KB8 DEDP--HRPPTSEELLTAYGYMRGFMTAHG-QPDQPRSARYILKDYVSGKLLYCHPPPGR
::: ..: . .. :.. ::. ::.. . : :.: .:. :.:.: : :::
NP_005 AEDPSAEHPWCAWDICEAWAEKRGYKTAKAARNDVYRAANSLLRLAVDGRLSLCFHPPGY
470 480 490 500 510 520
560 570 580 590 600 610
pF1KB8 DPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVM
NP_005 SEQKGTWESHPETTELVVLQGRVGPAGDEEEEEEEELSSSCEEEGEEDRDADEEGEGDEE
530 540 550 560 570 580
>>XP_005249072 (OMIM: 143024) PREDICTED: guanine nucleot (607 aa)
initn: 560 init1: 302 opt: 426 Z-score: 360.5 bits: 76.9 E(85289): 2.4e-13
Smith-Waterman score: 602; 31.0% identity (55.2% similar) in 449 aa overlap (111-552:127-522)
90 100 110 120 130 140
pF1KB8 KFVPAEARTGLLSFEESQRIKKLHEENKQFLCIPRRPNWNQNTTPEELKQAEKDNFLEWR
: .:::: :. . . :.: . :. .: ..
XP_005 KRAAREQVLQPVSAELLELDIREVYQPGSVLDFPRRPPWSYEMSKEQLMSQEERSFQDYL
100 110 120 130 140 150
150 160 170 180 190 200
pF1KB8 RQLVRLEEEQKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKE
.. .:: . ::.::. :::::::.: ::::. :.: :.:.. : ::
XP_005 GKIHGAYSSEKL--SYFEHNLETWRQLWRVLEMSDIVLLITDIRHPVVNFPPALYEYVTG
160 170 180 190 200 210
210 220 230 240 250
pF1KB8 MDANKENVILINKADLLTAEQRSAWAMYFEKE--DVKVIFWSALA--GAIPLNGDSEEEA
. . :...::.:: :: ::... ...:...... : . .: .
XP_005 -ELGLALVLVLNKVDLAPPALVVAWKHYFHQHYPQLHVVLFTSFPRDPRTPQDPSSVLKK
220 230 240 250 260 270
260 270 280 290 300 310
pF1KB8 NRDDRQSNTTEFGHSSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPEEEED
.: .. : .: .. .: :. . : : :. . : . . . :::.
XP_005 SRRRGRGWTRALGPEQLLRA----CEAITVGKVDLSSWREKIARDVAGATWGNGSGEEEE
280 290 300 310 320
320 330 340 350 360 370
pF1KB8 DWQTCSEEDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKEL
::::: . :: .: .
XP_005 ------EEDGP---------------------------------AVLVEQQTDSAMEPTG
330 340 350
380 390 400 410 420 430
pF1KB8 HTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLC
: .. ::: .:.: ::.::::::: :: ..: : :::: :::::..::: .. :.. ::
XP_005 PTQERYKDGVVTIGCVGFPNVGKSSLINGLVGRKVVSVSRTPGHTRYFQTYFLTPSVKLC
360 370 380 390 400 410
440 450 460 470 480 490
pF1KB8 DCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPRE
:::::..::.. . .. .:: :: :... :. . . :: ..: ... : :
XP_005 DCPGLIFPSLLPRQLQVL-AGIYPIAQIQEPYTAVGYLASRIPVQAL-----LHLRHP-E
420 430 440 450 460
500 510 520 530 540 550
pF1KB8 DEDP--HRPPTSEELLTAYGYMRGFMTAHG-QPDQPRSARYILKDYVSGKLLYCHPPPGR
::: ..: . .. :.. ::. ::.. . : :.: .:. :.:.: : :::
XP_005 AEDPSAEHPWCAWDICEAWAEKRGYKTAKAARNDVYRAANSLLRLAVDGRLSLCFHPPGY
470 480 490 500 510 520
560 570 580 590 600 610
pF1KB8 DPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVM
XP_005 SEQKGTWESHPETTELVVLQGRVGPAGDEEEEEEEELSSSCEEEGEEDRDADEEGEGDEE
530 540 550 560 570 580
>>NP_001310553 (OMIM: 609365) nucleolar GTP-binding prot (548 aa)
initn: 336 init1: 191 opt: 246 Z-score: 213.3 bits: 49.5 E(85289): 3.9e-05
Smith-Waterman score: 298; 28.6% identity (61.9% similar) in 189 aa overlap (368-556:113-285)
340 350 360 370 380 390
pF1KB8 ESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNV
.::. : .::: .: :..::..:::::
NP_001 KRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKK----QISVGFIGYPNV
90 100 110 120 130
400 410 420 430 440 450
pF1KB8 GKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSG
::::.:::. ..: .:. :.:: .: . . . : ::::.:.:: ....... .:
NP_001 GKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSE-DSETDIVLKG
140 150 160 170 180 190
460 470 480 490 500 510
pF1KB8 ILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMR
.. ...... .. : . . . :: :. :. .:..: ..
NP_001 VVQVEKIKSPEDHIGAVLERAKPEYISKTYKID---SWEN--------AEDFLEKLAFRT
200 210 220 230 240
520 530 540 550 560 570
pF1KB8 GFMTAHGQPDQPRSARYILKDYVSGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKM
: . :.:: ....:.:. :.. . ::. .:.
NP_001 GKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSSSLEVVPEAAQNN
250 260 270 280 290 300
580 590 600 610 620 630
pF1KB8 QLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVMGYKPGSGVVTASTASSENGAGKPW
NP_001 PGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDDLVP
310 320 330 340 350 360
>>NP_037417 (OMIM: 609365) nucleolar GTP-binding protein (731 aa)
initn: 336 init1: 191 opt: 246 Z-score: 211.4 bits: 49.6 E(85289): 4.9e-05
Smith-Waterman score: 298; 28.6% identity (61.9% similar) in 189 aa overlap (368-556:296-468)
340 350 360 370 380 390
pF1KB8 ESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNV
.::. : .::: .: :..::..:::::
NP_037 KRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQFGKLHTDKK----QISVGFIGYPNV
270 280 290 300 310 320
400 410 420 430 440 450
pF1KB8 GKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSG
::::.:::. ..: .:. :.:: .: . . . : ::::.:.:: ....... .:
NP_037 GKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVYPSE-DSETDIVLKG
330 340 350 360 370 380
460 470 480 490 500 510
pF1KB8 ILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMR
.. ...... .. : . . . :: :. :. .:..: ..
NP_037 VVQVEKIKSPEDHIGAVLERAKPEYISKTYKID---SWEN--------AEDFLEKLAFRT
390 400 410 420
520 530 540 550 560 570
pF1KB8 GFMTAHGQPDQPRSARYILKDYVSGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKM
: . :.:: ....:.:. :.. . ::. .:.
NP_037 GKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSSSLEVVPEAAQNN
430 440 450 460 470 480
580 590 600 610 620 630
pF1KB8 QLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVMGYKPGSGVVTASTASSENGAGKPW
NP_037 PGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGKINVVPQFSGDDLVP
490 500 510 520 530 540
>>NP_001310552 (OMIM: 609365) nucleolar GTP-binding prot (799 aa)
initn: 310 init1: 191 opt: 230 Z-score: 197.7 bits: 47.2 E(85289): 0.00028
Smith-Waterman score: 368; 23.7% identity (50.6% similar) in 443 aa overlap (120-556:166-536)
90 100 110 120 130 140
pF1KB8 GLLSFEESQRIKKLHEENKQFLCIPRRPNWNQNTTPEELKQAEKDNFLEWRRQLVRLEEE
: . . : :. :: : . :: : .
NP_001 DTESFETTFGPKSQRKRPNLFASDMQSLIENAEMSTESYDQG-KDRDLVTEDTGVRNEAQ
140 150 160 170 180 190
150 160 170 180 190 200
pF1KB8 QKLILTPFERNLDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEMDANKENVI
... . . : .:..::. ::.:::..:::.:. : .: :.:. :. ..
NP_001 EEIYKKGQSKRI--WGELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKHLIF
200 210 220 230 240 250
210 220 230 240 250 260
pF1KB8 LINKADLLTAEQRSAWAMYFEKEDVKVIFWSALAGAIPLNGDSEEEANRDDRQSNTTEFG
..:: ::. . . :. . .. . : ..: :. ::
NP_001 VLNKCDLVPTWATKRWVAVLSQDYPTLAFHASL----------------------TNPFG
260 270 280 290
270 280 290 300 310 320
pF1KB8 HSSFDQAEISHSESEHLPARDSPSLSENPTTDEDDSEYEDCPEEEEDDWQTCS------E
...: : . .. :: . .: : :: :. :: :
NP_001 KGAFIQLLRQFGKPWHLTFH---ALLGFPGL-----LCILCP------WSPCSFYVLWLE
300 310 320 330
330 340 350 360 370 380
pF1KB8 EDGPKEEDCSQDWKESSTADSEARSRKTPQKRQIHNFSHLVSKQELLELFKELHTGRKVK
. :: . . ...: .:. . : . .:. ::: .:
NP_001 RALPKFK---LQIPGQTSAPEGSRGTRLPYQ--------------ILKASCSLHTDKK--
340 350 360 370
390 400 410 420 430 440
pF1KB8 DGQLTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVM
:..::..:::::::::.:::. ..: .:. :.:: .: . . . : ::::.:.
NP_001 --QISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKVWQYITLMRRIFLIDCPGVVY
380 390 400 410 420 430
450 460 470 480 490 500
pF1KB8 PSFVSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRP
:: ....... .:.. ...... .. : . . . :: :.
NP_001 PSE-DSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYISKTYKID-----------SW
440 450 460 470 480
510 520 530 540 550 560
pF1KB8 PTSEELLTAYGYMRGFMTAHGQPDQPRSARYILKDYVSGKLLYCHPPPGRDPVTFQHQHQ
..:..: .. : . :.:: ....:.:. :.. . ::. .:.
NP_001 ENAEDFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLP
490 500 510 520 530 540
570 580 590 600 610 620
pF1KB8 RLLENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGVQAVMGYKPGSGVVT
NP_001 SSSLEVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILTRVRQNFGK
550 560 570 580 590 600
>>NP_001171748 (OMIM: 300873) guanine nucleotide-binding (582 aa)
initn: 383 init1: 171 opt: 194 Z-score: 170.2 bits: 41.6 E(85289): 0.0097
Smith-Waterman score: 265; 31.9% identity (59.0% similar) in 166 aa overlap (386-551:252-404)
360 370 380 390 400 410
pF1KB8 QIHNFSHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVS
.. ::.:: ::::::: ::.. .. ::.
NP_001 ESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVG
230 240 250 260 270 280
420 430 440 450 460 470
pF1KB8 ATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVC
:.:: :: .: .:.. . : : ::.: :. .... . . .... : : :: .
NP_001 AVPGITKFMQEVYLDKFIRLLDAPGIV-PG-PNSEVGTILRNCVHVQKLADPVTPVETIL
290 300 310 320 330
480 490 500 510 520 530
pF1KB8 QNIPRHVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMRGFMTAHGQPDQPRSARYI
: . . ::.. . :.:..::: .. : : .: ..:. .
NP_001 QRCNLEEISNYYGVSGFQ-----------TTEHFLTAVAHRLGKKKKGGLYSQEQAAKAV
340 350 360 370 380
540 550 560 570 580 590
pF1KB8 LKDYVSGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKT
: :.::::. . :::
NP_001 LADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANEDTMECLATGESDE
390 400 410 420 430 440
>>NP_061940 (OMIM: 300873) guanine nucleotide-binding pr (582 aa)
initn: 383 init1: 171 opt: 194 Z-score: 170.2 bits: 41.6 E(85289): 0.0097
Smith-Waterman score: 265; 31.9% identity (59.0% similar) in 166 aa overlap (386-551:252-404)
360 370 380 390 400 410
pF1KB8 QIHNFSHLVSKQELLELFKELHTGRKVKDGQLTVGLVGYPNVGKSSTINTIMGNKKVSVS
.. ::.:: ::::::: ::.. .. ::.
NP_061 ESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKRSRACSVG
230 240 250 260 270 280
420 430 440 450 460 470
pF1KB8 ATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEMTCSGILPIDQMRDHVPPVSLVC
:.:: :: .: .:.. . : : ::.: :. .... . . .... : : :: .
NP_061 AVPGITKFMQEVYLDKFIRLLDAPGIV-PG-PNSEVGTILRNCVHVQKLADPVTPVETIL
290 300 310 320 330
480 490 500 510 520 530
pF1KB8 QNIPRHVLEATYGINIITPREDEDPHRPPTSEELLTAYGYMRGFMTAHGQPDQPRSARYI
: . . ::.. . :.:..::: .. : : .: ..:. .
NP_061 QRCNLEEISNYYGVSGFQ-----------TTEHFLTAVAHRLGKKKKGGLYSQEQAAKAV
340 350 360 370 380
540 550 560 570 580 590
pF1KB8 LKDYVSGKLLYCHPPPGRDPVTFQHQHQRLLENKMNSDEIKMQLGRNKKAKQIENIVDKT
: :.::::. . :::
NP_061 LADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANEDTMECLATGESDE
390 400 410 420 430 440
658 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 09:14:32 2016 done: Sat Nov 5 09:14:34 2016
Total Scan time: 11.590 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]