Result of FASTA (omim) for
pFN21AE1076
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1076, 296 aa
1>>>pF1KE1076 296 - 296 aa - 296 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1416+/-0.000362; mu= 15.8644+/- 0.023
mean_var=59.4428+/-11.742, 0's: 0 Z-trim(112.4): 26 B-trim: 359 in 2/55
Lambda= 0.166351
statistics sampled from 21332 (21358) to 21332 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.622), E-opt: 0.2 (0.25), width: 16
Scan time: 6.790
The best scores are: opt bits E(85289)
NP_057043 (OMIM: 616715) thioredoxin-related trans ( 296) 1978 483.1 2.7e-136
NP_001137484 (OMIM: 616715) thioredoxin-related tr ( 258) 1172 289.7 4.1e-78
NP_110437 (OMIM: 616412) thioredoxin domain-contai ( 432) 147 43.8 0.00072
NP_110382 (OMIM: 610527) thioredoxin-related trans ( 280) 143 42.7 0.00097
NP_001258510 (OMIM: 607987) dnaJ homolog subfamily ( 747) 144 43.2 0.0019
NP_061854 (OMIM: 607987) dnaJ homolog subfamily C ( 793) 144 43.2 0.002
>>NP_057043 (OMIM: 616715) thioredoxin-related transmemb (296 aa)
initn: 1978 init1: 1978 opt: 1978 Z-score: 2567.8 bits: 483.1 E(85289): 2.7e-136
Smith-Waterman score: 1978; 100.0% identity (100.0% similar) in 296 aa overlap (1-296:1-296)
10 20 30 40 50 60
pF1KE1 MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FDWREVEILMFLSAIVMMKNRRSITVEQHIGNIFMFSKVANTILFFRLDIRMGLLYITLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FDWREVEILMFLSAIVMMKNRRSITVEQHIGNIFMFSKVANTILFFRLDIRMGLLYITLC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 IVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 SLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGR
190 200 210 220 230 240
250 260 270 280 290
pF1KE1 AVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTPTTVSDGENKKDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 AVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTPTTVSDGENKKDK
250 260 270 280 290
>>NP_001137484 (OMIM: 616715) thioredoxin-related transm (258 aa)
initn: 1172 init1: 1172 opt: 1172 Z-score: 1523.3 bits: 289.7 E(85289): 4.1e-78
Smith-Waterman score: 1646; 86.8% identity (87.2% similar) in 296 aa overlap (1-296:1-258)
10 20 30 40 50 60
pF1KE1 MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 FDWREVEILMFLSAIVMMKNRRSITVEQHIGNIFMFSKVANTILFFRLDIRMGLLYITLC
:::::::::::::::::::::::.
NP_001 FDWREVEILMFLSAIVMMKNRRSM------------------------------------
70 80
130 140 150 160 170 180
pF1KE1 IVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --FLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADL
90 100 110 120 130 140
190 200 210 220 230 240
pF1KE1 SLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGR
150 160 170 180 190 200
250 260 270 280 290
pF1KE1 AVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTPTTVSDGENKKDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTPTTVSDGENKKDK
210 220 230 240 250
>>NP_110437 (OMIM: 616412) thioredoxin domain-containing (432 aa)
initn: 188 init1: 94 opt: 147 Z-score: 190.4 bits: 43.8 E(85289): 0.00072
Smith-Waterman score: 147; 32.7% identity (58.2% similar) in 98 aa overlap (160-254:82-176)
130 140 150 160 170 180
pF1KE1 PLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGL
: ::: : . :: . : . ::. ::: ..
NP_110 ADGEDGQDPHSKHLYTADMFTHGIQSAAHFVMFFAPWCGHCQRLQPTWNDLGDKYN--SM
60 70 80 90 100
190 200 210 220 230 240
pF1KE1 NFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGRAVSW---TF
. .:: :.. .: ... : .. .. ::: ::. :.::.. .: :.
NP_110 EDAKVYVAK-VDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTL
110 120 130 140 150 160
250 260 270 280 290
pF1KE1 SEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVASTPTTVSDGENKKDK
.:: : :
NP_110 NEEPVTPEPEVEPPSAPELKQGLYELSASNFELHVAQGDHFIKFFAPWCGHCKALAPTWE
170 180 190 200 210 220
>>NP_110382 (OMIM: 610527) thioredoxin-related transmemb (280 aa)
initn: 97 init1: 97 opt: 143 Z-score: 188.1 bits: 42.7 E(85289): 0.00097
Smith-Waterman score: 143; 26.8% identity (54.5% similar) in 123 aa overlap (113-234:5-115)
90 100 110 120 130 140
pF1KE1 SITVEQHIGNIFMFSKVANTILFFRLDIRMGLLYITLCIVFLMTCKPPLYMGPEY-IKYF
: : . : .. :. : : . .. .
NP_110 MAPSGSLAVPLAVLVLLLWGAPWTHGRRSNVRVI
10 20 30
150 160 170 180 190 200
pF1KE1 NDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTD
.:.. : :: : :..::.: : ::.. : . ... . .:..:::: .
NP_110 TDENWRELLEGD----WMIEFYAPWCPACQNLQPEWESFAEWGEDLEVNIAKVDVTEQPG
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE1 VSTRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGRAVSWTFSEENVIREFNLNELY
.: :. ... :::. . :. .:: :
NP_110 LSGRFIITA------LPTIYHCKDGE--FRRYQGPRTKKDFINFISDKEWKSIEPVSSWF
100 110 120 130 140
270 280 290
pF1KE1 QRAKKLSKAGDNIPEEQPVASTPTTVSDGENKKDK
NP_110 GPGSVLMSSMSALFQLSMWIRTCHNYFIEDLGLPVWGSYTVFALATLFSGLLLGLCMIFV
150 160 170 180 190 200
>>NP_001258510 (OMIM: 607987) dnaJ homolog subfamily C m (747 aa)
initn: 97 init1: 97 opt: 144 Z-score: 182.9 bits: 43.2 E(85289): 0.0019
Smith-Waterman score: 144; 23.3% identity (62.1% similar) in 116 aa overlap (135-249:623-732)
110 120 130 140 150 160
pF1KE1 FFRLDIRMGLLYITLCIVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFA
:. .. .:..:.. . : :...:.:
NP_001 PKSNKAYHYHSYNGWNRDAYSLRIWGLGFLPQVSTDLTPQTFSEKVLQGKN-HWVIDFYA
600 610 620 630 640 650
170 180 190 200 210 220
pF1KE1 NWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQ
: . ::.::: . .: .. .. :::: :... . . . : .: . ...
NP_001 PWCGPCQNFAPEF-ELLARMIKGKVKAGKVDCQAYAQTCQKAGIRAYPTVK----FYFYE
660 670 680 690 700
230 240 250 260 270 280
pF1KE1 GGKEAMRRPQIDKK-GRAVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVAST
.:. ... ::. . ..:.. .::.
NP_001 RAKRNFQEEQINTRDAKAIAALISEKLETLRNQGKRNKDEL
710 720 730 740
>>NP_061854 (OMIM: 607987) dnaJ homolog subfamily C memb (793 aa)
initn: 97 init1: 97 opt: 144 Z-score: 182.5 bits: 43.2 E(85289): 0.002
Smith-Waterman score: 144; 23.3% identity (62.1% similar) in 116 aa overlap (135-249:669-778)
110 120 130 140 150 160
pF1KE1 FFRLDIRMGLLYITLCIVFLMTCKPPLYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFA
:. .. .:..:.. . : :...:.:
NP_061 PKSNKAYHYHSYNGWNRDAYSLRIWGLGFLPQVSTDLTPQTFSEKVLQGKN-HWVIDFYA
640 650 660 670 680 690
170 180 190 200 210 220
pF1KE1 NWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVSTSPLTKQLPTLILFQ
: . ::.::: . .: .. .. :::: :... . . . : .: . ...
NP_061 PWCGPCQNFAPEF-ELLARMIKGKVKAGKVDCQAYAQTCQKAGIRAYPTVK----FYFYE
700 710 720 730 740 750
230 240 250 260 270 280
pF1KE1 GGKEAMRRPQIDKK-GRAVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPVAST
.:. ... ::. . ..:.. .::.
NP_061 RAKRNFQEEQINTRDAKAIAALISEKLETLRNQGKRNKDEL
760 770 780 790
296 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 19:33:36 2016 done: Sat Nov 5 19:33:37 2016
Total Scan time: 6.790 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]