Result of FASTA (omim) for
pFN21AE1034
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1034, 424 aa
1>>>pF1KE1034 424 - 424 aa - 424 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4691+/-0.000374; mu= 17.0500+/- 0.023
mean_var=77.5265+/-15.991, 0's: 0 Z-trim(113.6): 51 B-trim: 296 in 1/54
Lambda= 0.145663
statistics sampled from 23017 (23059) to 23017 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.635), E-opt: 0.2 (0.27), width: 16
Scan time: 9.460
The best scores are: opt bits E(85289)
NP_001598 (OMIM: 604054) 3-ketoacyl-CoA thiolase, ( 424) 2767 591.1 1.7e-168
XP_011531952 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 279) 1802 388.2 1.4e-107
XP_006713185 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 364) 1792 386.2 7.4e-107
XP_006713186 (OMIM: 604054) PREDICTED: 3-ketoacyl- ( 272) 1753 377.9 1.7e-104
NP_001123882 (OMIM: 604054) 3-ketoacyl-CoA thiolas ( 331) 1020 223.9 4.7e-58
NP_005882 (OMIM: 100678,614055) acetyl-CoA acetylt ( 397) 843 186.8 8.6e-47
NP_001290182 (OMIM: 100678,614055) acetyl-CoA acet ( 426) 827 183.4 9.3e-46
NP_006102 (OMIM: 604770) 3-ketoacyl-CoA thiolase, ( 397) 805 178.8 2.2e-44
NP_000010 (OMIM: 203750,607809) acetyl-CoA acetylt ( 427) 663 149.0 2.2e-35
XP_016873170 (OMIM: 203750,607809) PREDICTED: acet ( 337) 635 143.0 1.1e-33
XP_006718898 (OMIM: 203750,607809) PREDICTED: acet ( 337) 635 143.0 1.1e-33
XP_016873172 (OMIM: 203750,607809) PREDICTED: acet ( 301) 515 117.8 3.9e-26
XP_016873171 (OMIM: 203750,607809) PREDICTED: acet ( 301) 515 117.8 3.9e-26
NP_001268441 (OMIM: 143450,609015) trifunctional e ( 459) 364 86.2 1.9e-16
NP_000174 (OMIM: 143450,609015) trifunctional enzy ( 474) 189 49.4 2.3e-05
XP_011531105 (OMIM: 143450,609015) PREDICTED: trif ( 474) 189 49.4 2.3e-05
XP_016859428 (OMIM: 143450,609015) PREDICTED: trif ( 481) 189 49.4 2.4e-05
NP_001268442 (OMIM: 143450,609015) trifunctional e ( 452) 186 48.7 3.5e-05
>>NP_001598 (OMIM: 604054) 3-ketoacyl-CoA thiolase, pero (424 aa)
initn: 2767 init1: 2767 opt: 2767 Z-score: 3145.8 bits: 591.1 E(85289): 1.7e-168
Smith-Waterman score: 2767; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)
10 20 30 40 50 60
pF1KE1 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 MGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 LGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
370 380 390 400 410 420
pF1KE1 YPGN
::::
NP_001 YPGN
>>XP_011531952 (OMIM: 604054) PREDICTED: 3-ketoacyl-CoA (279 aa)
initn: 1802 init1: 1802 opt: 1802 Z-score: 2052.4 bits: 388.2 E(85289): 1.4e-107
Smith-Waterman score: 1802; 100.0% identity (100.0% similar) in 279 aa overlap (146-424:1-279)
120 130 140 150 160 170
pF1KE1 LSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKAR
::::::::::::::::::::::::::::::
XP_011 MACGVESMSLADRGNPGNITSRLMEKEKAR
10 20 30
180 190 200 210 220 230
pF1KE1 DCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKG
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE1 TKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEE
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE1 LGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYC
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE1 VEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGA
220 230 240 250 260 270
420
pF1KE1 AAVFEYPGN
:::::::::
XP_011 AAVFEYPGN
>>XP_006713185 (OMIM: 604054) PREDICTED: 3-ketoacyl-CoA (364 aa)
initn: 1789 init1: 1789 opt: 1792 Z-score: 2039.4 bits: 386.2 E(85289): 7.4e-107
Smith-Waterman score: 2261; 85.8% identity (85.8% similar) in 424 aa overlap (1-424:1-364)
10 20 30 40 50 60
pF1KE1 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 MGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPI
:::::::::::::::::::::::::::::::::
XP_006 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAG---------------------------
250 260 270
310 320 330 340 350 360
pF1KE1 LGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLR
:::::::::::::::::::::::::::
XP_006 ---------------------------------LTVSDVDIFEINEAFASQAAYCVEKLR
280 290 300
370 380 390 400 410 420
pF1KE1 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
310 320 330 340 350 360
pF1KE1 YPGN
::::
XP_006 YPGN
>>XP_006713186 (OMIM: 604054) PREDICTED: 3-ketoacyl-CoA (272 aa)
initn: 1753 init1: 1753 opt: 1753 Z-score: 1996.9 bits: 377.9 E(85289): 1.7e-104
Smith-Waterman score: 1753; 100.0% identity (100.0% similar) in 272 aa overlap (153-424:1-272)
130 140 150 160 170 180
pF1KE1 CSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIPMG
::::::::::::::::::::::::::::::
XP_006 MSLADRGNPGNITSRLMEKEKARDCLIPMG
10 20 30
190 200 210 220 230 240
pF1KE1 ITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITV
40 50 60 70 80 90
250 260 270 280 290 300
pF1KE1 TQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPILG
100 110 120 130 140 150
310 320 330 340 350 360
pF1KE1 VLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLP
160 170 180 190 200 210
370 380 390 400 410 420
pF1KE1 PEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYP
220 230 240 250 260 270
pF1KE1 GN
::
XP_006 GN
>>NP_001123882 (OMIM: 604054) 3-ketoacyl-CoA thiolase, p (331 aa)
initn: 1621 init1: 1020 opt: 1020 Z-score: 1163.2 bits: 223.9 E(85289): 4.7e-58
Smith-Waterman score: 1966; 78.1% identity (78.1% similar) in 424 aa overlap (1-424:1-331)
10 20 30 40 50 60
pF1KE1 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIP
:::::::::::::::::::::::::::::
NP_001 RQCSSGLQAVASIAGGIRNGSYDIGMACG-------------------------------
130 140
190 200 210 220 230 240
pF1KE1 MGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --ITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE1 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPI
:::::::::::::::::::::::::::::::::
NP_001 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAG---------------------------
210 220 230 240
310 320 330 340 350 360
pF1KE1 LGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLR
:::::::::::::::::::::::::::
NP_001 ---------------------------------LTVSDVDIFEINEAFASQAAYCVEKLR
250 260
370 380 390 400 410 420
pF1KE1 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
270 280 290 300 310 320
pF1KE1 YPGN
::::
NP_001 YPGN
330
>>NP_005882 (OMIM: 100678,614055) acetyl-CoA acetyltrans (397 aa)
initn: 817 init1: 414 opt: 843 Z-score: 961.1 bits: 186.8 E(85289): 8.6e-47
Smith-Waterman score: 843; 41.7% identity (66.6% similar) in 398 aa overlap (33-416:3-391)
10 20 30 40 50 60
pF1KE1 RLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPD
:.. ::.: . :: : . :.. . .
NP_005 MNAGSDPVVIVSAARTIIG-SFNGALAAVPVQ
10 20 30
70 80 90 100 110 120
pF1KE1 ELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQ
.: :.:. ::: ... ::..... :.:: : : .: :. . :: .:: . .
NP_005 DLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMI
40 50 60 70 80 90
130 140 150 160 170
pF1KE1 CSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADR----------GNPGNITSRLME--
:.:::.:: . .: :. .: .: :.:.:: : . :. : : .
NP_005 CGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGL
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 KEKARDCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTV
. ..: ::::.::::... .::: :: :. ::... ::. : :. ::::: ...
NP_005 TDAFHNC--HMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVST
160 170 180 190 200
240 250 260 270 280
pF1KE1 HDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGS--TTAGNSSQVSDGAAAILLA
. :: : : :: : ....:...:::: : ::. .: .:.: ..:::::..:
NP_005 R--KGL---IEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLM
210 220 230 240 250 260
290 300 310 320 330 340
pF1KE1 RRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAF
..:.:.. :: :. . :.. ::: :.:::::: :: :. ::: .. :::::::::::
NP_005 KKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAF
270 280 290 300 310 320
350 360 370 380 390 400
pF1KE1 ASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMC
:. .: :..: : ::::: :::.::::::: .: : ..:::. :.: : :. ::...:
NP_005 AAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMG-RSRGVAALC
330 340 350 360 370 380
410 420
pF1KE1 IGTGMGAAAVFEYPGN
:: ::: :
NP_005 IGGGMGIAMCVQRE
390
>>NP_001290182 (OMIM: 100678,614055) acetyl-CoA acetyltr (426 aa)
initn: 817 init1: 414 opt: 827 Z-score: 942.5 bits: 183.4 E(85289): 9.3e-46
Smith-Waterman score: 827; 42.2% identity (67.1% similar) in 377 aa overlap (54-416:52-420)
30 40 50 60 70 80
pF1KE1 APCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLKDVNLRPEQL
:.. . ..: :.:. ::: ... ::..
NP_001 RSGGRLSSPRLLRVVAPTLTFAQTSRCSFNGALAAVPVQDLGSTVIKEVLKRATVAPEDV
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE1 GDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYD
... :.:: : : .: :. . :: .:: . . :.:::.:: . .: :. .
NP_001 SEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSS
90 100 110 120 130 140
150 160 170 180 190
pF1KE1 IGMACGVESMSLADR----------GNPGNITSRLME--KEKARDCLIPMGITSENVAER
: .: :.:.:: : . :. : : . . ..: ::::.::::..
NP_001 IVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNC--HMGITAENVAKK
150 160 170 180 190
200 210 220 230 240 250
pF1KE1 FGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPS
. .::: :: :. ::... ::. : :. ::::: .... :: : : :: : .
NP_001 WQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTR--KGL---IEVKTDEFPRHG
200 210 220 230 240 250
260 270 280 290 300
pF1KE1 TTMEGLAKLKPAFKKDGS--TTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAV
...:...:::: : ::. .: .:.: ..:::::..: ..:.:.. :: :. . :..
NP_001 SNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQ
260 270 280 290 300 310
310 320 330 340 350 360
pF1KE1 VGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPL
::: :.:::::: :: :. ::: .. ::::::::::::. .: :..: : :::::
NP_001 VGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIE
320 330 340 350 360 370
370 380 390 400 410 420
pF1KE1 GGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFEYPGN
:::.::::::: .: : ..:::. :.: : :. ::...::: ::: :
NP_001 GGAIALGHPLGASGCRILVTLLHTLERMG-RSRGVAALCIGGGMGIAMCVQRE
380 390 400 410 420
>>NP_006102 (OMIM: 604770) 3-ketoacyl-CoA thiolase, mito (397 aa)
initn: 774 init1: 477 opt: 805 Z-score: 917.9 bits: 178.8 E(85289): 2.2e-44
Smith-Waterman score: 805; 39.2% identity (65.6% similar) in 395 aa overlap (38-420:7-394)
10 20 30 40 50 60
pF1KE1 LGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSA
: :: ..:: . : : .:: : .:
NP_006 MALLRGVFVVAAKRTPFGAYG-GLLKDFTATDLSEF
10 20 30
70 80 90 100 110 120
pF1KE1 VMTAVLKDVNLRPEQLGDICVGNVLQPGAGAI-MARIAQFLSDIPETVPLSTVNRQCSSG
. :.:. .. :: . .. .::::: .. :: .:: . . ::. .: :.:: :.::
NP_006 AAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSG
40 50 60 70 80 90
130 140 150 160 170
pF1KE1 LQAVASIAGGIRNGSYDIGMACGVESMSLADR-----------GNPGNITSRLMEKEKAR
.:.... : .. . :.:::: : :. .. . : . .
NP_006 FQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQ
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 DCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKG
.::..:.::.: . ::::. : .:: :::. :.. : :. :..:. :. ::
NP_006 HVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPI--EVKTKKG
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE1 TKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEE
:... : :: ::.::.: : :: :.:::::..::::.: :.:::.:...: .. ...
NP_006 -KQTMQV--DEHARPQTTLEQLQKLPPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKK
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE1 LGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYC
.. :. . .: : : :.::::::. :: ::.::::...:.:. :.::::: :
NP_006 HNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAV
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE1 VEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGA
..: : :.: :::.::::::: .:.: . :..::.::: . :.: : ::: :.:
NP_006 ERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGK-YAVGSACIGGGQGI
340 350 360 370 380
420
pF1KE1 AAVFEYPGN
:....
NP_006 AVIIQSTA
390
>>NP_000010 (OMIM: 203750,607809) acetyl-CoA acetyltrans (427 aa)
initn: 594 init1: 309 opt: 663 Z-score: 756.2 bits: 149.0 E(85289): 2.2e-35
Smith-Waterman score: 663; 33.6% identity (65.7% similar) in 402 aa overlap (28-419:32-423)
10 20 30 40 50
pF1KE1 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFK
: . . . .::.: . :: : . :...
NP_000 AVLAALLRSGARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRTPIG-SFLGSLS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 DTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLS
.: : .. .... ... :.. . .::::: : : .: : . . .: ..: .
NP_000 LLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 TVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS----LADRGN-P-GNITSR-LME
:.:. :.::..:. . .. : :. .: :.:::: . .::. : :.. . :.
NP_000 TINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIV
130 140 150 160 170 180
180 190 200 210 220
pF1KE1 KEKARDCL--IPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTT
:. : : :: .::.:....:.:..::..:. : .. : : : :..:::.
NP_000 KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE1 TVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD-GSTTAGNSSQVSDGAAAILL
:: :: . ...: .:: . . . . ::: .:.:. :..::.:.: ..:::::..:
NP_000 TV---KG-QPDVVVKEDEEYK-RVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVL
250 260 270 280 290
290 300 310 320 330 340
pF1KE1 ARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEA
. :..:.. :. . ..: ..: : . :.:.:: ..:. .:: :. ..:.:::
NP_000 MTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEA
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE1 FASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSM
:. . .. :.. :.::: ::::.::::.: .::: : : . ::. :. ::..:.
NP_000 FSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ-GE--YGLASI
360 370 380 390 400 410
410 420
pF1KE1 CIGTGMGAAAVFEYPGN
: : : ::.:..
NP_000 CNGGG-GASAMLIQKL
420
>>XP_016873170 (OMIM: 203750,607809) PREDICTED: acetyl-C (337 aa)
initn: 582 init1: 309 opt: 635 Z-score: 725.9 bits: 143.0 E(85289): 1.1e-33
Smith-Waterman score: 635; 36.3% identity (67.3% similar) in 342 aa overlap (88-419:1-333)
60 70 80 90 100 110
pF1KE1 DTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLS
.::::: : : .: : . . .: ..: .
XP_016 MGNVLQGGEGQAPTRQAVLGAGLPISTPCT
10 20 30
120 130 140 150 160 170
pF1KE1 TVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS----LADRGN-P-GNITSR-LME
:.:. :.::..:. . .. : :. .: :.:::: . .::. : :.. . :.
XP_016 TINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIV
40 50 60 70 80 90
180 190 200 210 220
pF1KE1 KEKARDCL--IPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTT
:. : : :: .::.:....:.:..::..:. : .. : : : :..:::.
XP_016 KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE1 TVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD-GSTTAGNSSQVSDGAAAILL
:: :: . ...: .:: . . . . ::: .:.:. :..::.:.: ..:::::..:
XP_016 TV---KG-QPDVVVKEDEEYK-RVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVL
160 170 180 190 200
290 300 310 320 330 340
pF1KE1 ARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEA
. :..:.. :. . ..: ..: : . :.:.:: ..:. .:: :. ..:.:::
XP_016 MTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEA
210 220 230 240 250 260
350 360 370 380 390 400
pF1KE1 FASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSM
:. . .. :.. :.::: ::::.::::.: .::: : : . ::. :. ::..:.
XP_016 FSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ-GE--YGLASI
270 280 290 300 310 320
410 420
pF1KE1 CIGTGMGAAAVFEYPGN
: : : ::.:..
XP_016 CNGGG-GASAMLIQKL
330
424 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:40:11 2016 done: Sat Nov 5 07:40:13 2016
Total Scan time: 9.460 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]