Result of FASTA (ccds) for
pFN21AE1034
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE1034, 424 aa
1>>>pF1KE1034 424 - 424 aa - 424 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0512+/-0.000894; mu= 13.3288+/- 0.053
mean_var=74.4832+/-14.941, 0's: 0 Z-trim(106.8): 28 B-trim: 0 in 0/52
Lambda= 0.148609
statistics sampled from 9182 (9197) to 9182 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.283), width: 16
Scan time: 3.000
The best scores are: opt bits E(32554)
CCDS2673.1 ACAA1 gene_id:30|Hs108|chr3 ( 424) 2767 602.6 2.3e-172
CCDS46794.1 ACAA1 gene_id:30|Hs108|chr3 ( 331) 1020 228.1 1e-59
CCDS5268.1 ACAT2 gene_id:39|Hs108|chr6 ( 397) 843 190.1 3.2e-48
CCDS11939.1 ACAA2 gene_id:10449|Hs108|chr18 ( 397) 805 182.0 9e-46
CCDS8339.1 ACAT1 gene_id:38|Hs108|chr11 ( 427) 663 151.6 1.4e-36
CCDS62871.1 HADHB gene_id:3032|Hs108|chr2 ( 459) 364 87.5 3e-17
>>CCDS2673.1 ACAA1 gene_id:30|Hs108|chr3 (424 aa)
initn: 2767 init1: 2767 opt: 2767 Z-score: 3208.1 bits: 602.6 E(32554): 2.3e-172
Smith-Waterman score: 2767; 100.0% identity (100.0% similar) in 424 aa overlap (1-424:1-424)
10 20 30 40 50 60
pF1KE1 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 RQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE1 MGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 MGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE1 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE1 LGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 LGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE1 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS26 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
370 380 390 400 410 420
pF1KE1 YPGN
::::
CCDS26 YPGN
>>CCDS46794.1 ACAA1 gene_id:30|Hs108|chr3 (331 aa)
initn: 1621 init1: 1020 opt: 1020 Z-score: 1185.6 bits: 228.1 E(32554): 1e-59
Smith-Waterman score: 1966; 78.1% identity (78.1% similar) in 424 aa overlap (1-424:1-331)
10 20 30 40 50 60
pF1KE1 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE1 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 PDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE1 RQCSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADRGNPGNITSRLMEKEKARDCLIP
:::::::::::::::::::::::::::::
CCDS46 RQCSSGLQAVASIAGGIRNGSYDIGMACG-------------------------------
130 140
190 200 210 220 230 240
pF1KE1 MGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 --ITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSI
150 160 170 180 190 200
250 260 270 280 290 300
pF1KE1 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEELGLPI
:::::::::::::::::::::::::::::::::
CCDS46 TVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAG---------------------------
210 220 230 240
310 320 330 340 350 360
pF1KE1 LGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLR
:::::::::::::::::::::::::::
CCDS46 ---------------------------------LTVSDVDIFEINEAFASQAAYCVEKLR
250 260
370 380 390 400 410 420
pF1KE1 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 LPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE
270 280 290 300 310 320
pF1KE1 YPGN
::::
CCDS46 YPGN
330
>>CCDS5268.1 ACAT2 gene_id:39|Hs108|chr6 (397 aa)
initn: 817 init1: 414 opt: 843 Z-score: 979.2 bits: 190.1 E(32554): 3.2e-48
Smith-Waterman score: 843; 41.7% identity (66.6% similar) in 398 aa overlap (33-416:3-391)
10 20 30 40 50 60
pF1KE1 RLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPD
:.. ::.: . :: : . :.. . .
CCDS52 MNAGSDPVVIVSAARTIIG-SFNGALAAVPVQ
10 20 30
70 80 90 100 110 120
pF1KE1 ELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQ
.: :.:. ::: ... ::..... :.:: : : .: :. . :: .:: . .
CCDS52 DLGSTVIKEVLKRATVAPEDVSEVIFGHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMI
40 50 60 70 80 90
130 140 150 160 170
pF1KE1 CSSGLQAVASIAGGIRNGSYDIGMACGVESMSLADR----------GNPGNITSRLME--
:.:::.:: . .: :. .: .: :.:.:: : . :. : : .
CCDS52 CGSGLKAVCLAVQSIGIGDSSIVVAGGMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGL
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 KEKARDCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTV
. ..: ::::.::::... .::: :: :. ::... ::. : :. ::::: ...
CCDS52 TDAFHNC--HMGITAENVAKKWQVSREDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVST
160 170 180 190 200
240 250 260 270 280
pF1KE1 HDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGS--TTAGNSSQVSDGAAAILLA
. :: : : :: : ....:...:::: : ::. .: .:.: ..:::::..:
CCDS52 R--KGL---IEVKTDEFPRHGSNIEAMSKLKPYFLTDGTGTVTPANASGINDGAAAVVLM
210 220 230 240 250 260
290 300 310 320 330 340
pF1KE1 RRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAF
..:.:.. :: :. . :.. ::: :.:::::: :: :. ::: .. :::::::::::
CCDS52 KKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPAIKQAVTKAGWSLEDVDIFEINEAF
270 280 290 300 310 320
350 360 370 380 390 400
pF1KE1 ASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMC
:. .: :..: : ::::: :::.::::::: .: : ..:::. :.: : :. ::...:
CCDS52 AAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGCRILVTLLHTLERMG-RSRGVAALC
330 340 350 360 370 380
410 420
pF1KE1 IGTGMGAAAVFEYPGN
:: ::: :
CCDS52 IGGGMGIAMCVQRE
390
>>CCDS11939.1 ACAA2 gene_id:10449|Hs108|chr18 (397 aa)
initn: 774 init1: 477 opt: 805 Z-score: 935.2 bits: 182.0 E(32554): 9e-46
Smith-Waterman score: 805; 39.2% identity (65.6% similar) in 395 aa overlap (38-420:7-394)
10 20 30 40 50 60
pF1KE1 LGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFKDTTPDELLSA
: :: ..:: . : : .:: : .:
CCDS11 MALLRGVFVVAAKRTPFGAYG-GLLKDFTATDLSEF
10 20 30
70 80 90 100 110 120
pF1KE1 VMTAVLKDVNLRPEQLGDICVGNVLQPGAGAI-MARIAQFLSDIPETVPLSTVNRQCSSG
. :.:. .. :: . .. .::::: .. :: .:: . . ::. .: :.:: :.::
CCDS11 AAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSG
40 50 60 70 80 90
130 140 150 160 170
pF1KE1 LQAVASIAGGIRNGSYDIGMACGVESMSLADR-----------GNPGNITSRLMEKEKAR
.:.... : .. . :.:::: : :. .. . : . .
CCDS11 FQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQ
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE1 DCLIPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKG
.::..:.::.: . ::::. : .:: :::. :.. : :. :..:. :. ::
CCDS11 HVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFNDEMAPI--EVKTKKG
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE1 TKRSITVTQDEGIRPSTTMEGLAKLKPAFKKDGSTTAGNSSQVSDGAAAILLARRSKAEE
:... : :: ::.::.: : :: :.:::::..::::.: :.:::.:...: .. ...
CCDS11 -KQTMQV--DEHARPQTTLEQLQKLPPVFKKDGTVTAGNASGVADGAGAVIIASEDAVKK
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE1 LGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQAAYC
.. :. . .: : : :.::::::. :: ::.::::...:.:. :.::::: :
CCDS11 HNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAV
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE1 VEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGA
..: : :.: :::.::::::: .:.: . :..::.::: . :.: : ::: :.:
CCDS11 ERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGK-YAVGSACIGGGQGI
340 350 360 370 380
420
pF1KE1 AAVFEYPGN
:....
CCDS11 AVIIQSTA
390
>>CCDS8339.1 ACAT1 gene_id:38|Hs108|chr11 (427 aa)
initn: 594 init1: 309 opt: 663 Z-score: 770.2 bits: 151.6 E(32554): 1.4e-36
Smith-Waterman score: 663; 33.6% identity (65.7% similar) in 402 aa overlap (28-419:32-423)
10 20 30 40 50
pF1KE1 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAADVVVVHGRRTAICRAGRGGFK
: . . . .::.: . :: : . :...
CCDS83 AVLAALLRSGARSRSPLLRRLVQEIRYVERSYVSKPTLKEVVIVSATRTPIG-SFLGSLS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE1 DTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIAQFLSDIPETVPLS
.: : .. .... ... :.. . .::::: : : .: : . . .: ..: .
CCDS83 LLPATKLGSIAIQGAIEKAGIPKEEVKEAYMGNVLQGGEGQAPTRQAVLGAGLPISTPCT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE1 TVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS----LADRGN-P-GNITSR-LME
:.:. :.::..:. . .. : :. .: :.:::: . .::. : :.. . :.
CCDS83 TINKVCASGMKAIMMASQSLMCGHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIV
130 140 150 160 170 180
180 190 200 210 220
pF1KE1 KEKARDCL--IPMGITSENVAERFGISREKQDTFALASQQKAARAQSKGCFQAEIVPVTT
:. : : :: .::.:....:.:..::..:. : .. : : : :..:::.
CCDS83 KDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAYAINSYTRSKAAWEAGKFGNEVIPVTV
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE1 TVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD-GSTTAGNSSQVSDGAAAILL
:: :: . ...: .:: . . . . ::: .:.:. :..::.:.: ..:::::..:
CCDS83 TV---KG-QPDVVVKEDEEYK-RVDFSKVPKLKTVFQKENGTVTAANASTLNDGAAALVL
250 260 270 280 290
290 300 310 320 330 340
pF1KE1 ARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVALQKAGLTVSDVDIFEINEA
. :..:.. :. . ..: ..: : . :.:.:: ..:. .:: :. ..:.:::
CCDS83 MTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYAASMVLKDVGLKKEDIAMWEVNEA
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE1 FASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSM
:. . .. :.. :.::: ::::.::::.: .::: : : . ::. :. ::..:.
CCDS83 FSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGARIVGHLTHALKQ-GE--YGLASI
360 370 380 390 400 410
410 420
pF1KE1 CIGTGMGAAAVFEYPGN
: : : ::.:..
CCDS83 CNGGG-GASAMLIQKL
420
>>CCDS62871.1 HADHB gene_id:3032|Hs108|chr2 (459 aa)
initn: 626 init1: 148 opt: 364 Z-score: 423.2 bits: 87.5 E(32554): 3e-17
Smith-Waterman score: 623; 33.2% identity (58.2% similar) in 455 aa overlap (22-422:33-458)
10 20 30 40
pF1KE1 MQRLQVVLGHLRGPADSGWMPQAAPCLSGAPQASAA-----DVVVVHGRRT
.::: .. . . : .:::: : ::
CCDS62 ILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDGVRT
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE1 AICRAGRGGF--KDTTPDELLSAVMTAVLKDVNLRPEQLGDICVGNVLQPGAGAIMARIA
. .: .:. . ..: :... .. :.:.: . .:: :
CCDS62 PFLLSGTSGLLHRTSVPKEVVDYII------------------FGTVIQEVKTSNVAREA
70 80 90 100
110 120 130 140 150
pF1KE1 QFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVESMS----------
. . . . .: ::. : :. ::... .: : .:. :. .: ::: ::
CCDS62 ALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKM
110 120 130 140 150 160
160 170 180 190
pF1KE1 ---LADRGNPGNITSRLMEKEKAR-DCLIP-------------MGITSENVAERFGISRE
. : .. .. .:: : : . : : :: ... .: :..::
CCDS62 RKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRL
170 180 190 200 210 220
200 210 220 230 240 250
pF1KE1 KQDTFALASQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGL
.:: .:: :.. : .::..: . ...:: . .: :::.:.:::::. .: .
CCDS62 EQDEYALRSHSLAKKAQDEGLL-SDVVPFKVPGKD--------TVTKDNGIRPSS-LEQM
230 240 250 260 270
260 270 280 290 300 310
pF1KE1 AKLKPAFKKD-GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPP-D
::::::: : :..::.::: ..:::.:.:. . :: .: . ::.. :. : :
CCDS62 AKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKD
280 290 300 310 320 330
320 330 340 350
pF1KE1 IMGIGPAYAIPVALQKAGLTVSDVDIFEINEAFASQ---------AAYCVE-------KL
. .::.:: : .:.:::::..:.: ::..:::..: . . .: :.
CCDS62 QLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKV
340 350 360 370 380 390
360 370 380 390 400 410
pF1KE1 RLPP-EKVNPLGGAVALGHPLGCTGARQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAV
::: :: : ::...::::.: :: : :.. :.:...: . ::.:. : . :.: : .
CCDS62 GLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQ-YGLVAACAAGGQGHAMI
400 410 420 430 440 450
420
pF1KE1 FE-YPGN
: ::
CCDS62 VEAYPK
424 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:40:11 2016 done: Sat Nov 5 07:40:11 2016
Total Scan time: 3.000 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]