Result of FASTA (omim) for
pFN21AB6014
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6014, 698 aa
1>>>pF1KB6014 698 - 698 aa - 698 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8349+/-0.000304; mu= 18.5172+/- 0.019
mean_var=86.1692+/-17.431, 0's: 0 Z-trim(119.1): 27 B-trim: 0 in 0/54
Lambda= 0.138165
statistics sampled from 32655 (32683) to 32655 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.383), width: 16
Scan time: 12.920
The best scores are: opt bits E(85289)
NP_859052 (OMIM: 612860) sulfhydryl oxidase 2 prec ( 698) 4775 961.6 0
NP_002817 (OMIM: 603120) sulfhydryl oxidase 1 isof ( 747) 1609 330.5 1.4e-89
NP_001004128 (OMIM: 603120) sulfhydryl oxidase 1 i ( 604) 1587 326.1 2.5e-88
XP_011508610 (OMIM: 611099) PREDICTED: protein dis ( 402) 228 55.1 6.2e-07
NP_001269636 (OMIM: 611099) protein disulfide-isom ( 437) 228 55.1 6.6e-07
NP_005733 (OMIM: 611099) protein disulfide-isomera ( 440) 228 55.1 6.7e-07
NP_001269635 (OMIM: 611099) protein disulfide-isom ( 445) 228 55.1 6.7e-07
NP_001269634 (OMIM: 611099) protein disulfide-isom ( 488) 228 55.2 7.3e-07
NP_001269633 (OMIM: 611099) protein disulfide-isom ( 492) 228 55.2 7.3e-07
NP_000909 (OMIM: 112240,176790) protein disulfide- ( 508) 207 51.0 1.4e-05
NP_001139021 (OMIM: 616412) thioredoxin domain-con ( 324) 200 49.5 2.5e-05
NP_110437 (OMIM: 616412) thioredoxin domain-contai ( 432) 200 49.5 3.2e-05
NP_006801 (OMIM: 616942) protein disulfide-isomera ( 519) 198 49.2 4.8e-05
NP_005304 (OMIM: 602046) protein disulfide-isomera ( 505) 179 45.4 0.00065
XP_011524337 (OMIM: 616102) PREDICTED: protein dis ( 229) 171 43.6 0.001
XP_011524336 (OMIM: 616102) PREDICTED: protein dis ( 231) 171 43.6 0.001
NP_001258510 (OMIM: 607987) dnaJ homolog subfamily ( 747) 174 44.5 0.0018
NP_061895 (OMIM: 616102) protein disulfide-isomera ( 454) 171 43.8 0.0018
NP_061854 (OMIM: 607987) dnaJ homolog subfamily C ( 793) 174 44.5 0.0019
NP_006840 (OMIM: 608012) protein disulfide-isomera ( 525) 161 41.8 0.0081
>>NP_859052 (OMIM: 612860) sulfhydryl oxidase 2 precurso (698 aa)
initn: 4775 init1: 4775 opt: 4775 Z-score: 5140.3 bits: 961.6 E(85289): 0
Smith-Waterman score: 4775; 100.0% identity (100.0% similar) in 698 aa overlap (1-698:1-698)
10 20 30 40 50 60
pF1KB6 MAAAGAAVARSPGIGAGPALRARRSPPPRAARLPRLLVLLAAAAVGPGAGGAARLYRAGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 MAAAGAAVARSPGIGAGPALRARRSPPPRAARLPRLLVLLAAAAVGPGAGGAARLYRAGE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 DAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 DAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 DCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDRELRTVRQTMIDFLQNHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 DCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDRELRTVRQTMIDFLQNHT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVVTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 EGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVVTR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 ALDGDKAFLEKLGVSSVPSCYLIYPNGSHGLINVVKPLRAFFSSYLKSLPDVRKKSLPLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 ALDGDKAFLEKLGVSSVPSCYLIYPNGSHGLINVVKPLRAFFSSYLKSLPDVRKKSLPLP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 EKPHKEENSEIVVWREFDKSKLYTVDLESGLHYLLRVELAAHKSLAGAELKTLKDFVTVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 EKPHKEENSEIVVWREFDKSKLYTVDLESGLHYLLRVELAAHKSLAGAELKTLKDFVTVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 AKLFPGRPPVKKLLEMLQEWLASLPLDRIPYNAVLDLVNNKMRISGIFLTNHIKWVGCQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 AKLFPGRPPVKKLLEMLQEWLASLPLDRIPYNAVLDLVNNKMRISGIFLTNHIKWVGCQG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 SRSELRGYPCSLWKLFHTLTVEASTHPDALVGTGFEDDPQAVLQTMRRYVHTFFGCKECG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 SRSELRGYPCSLWKLFHTLTVEASTHPDALVGTGFEDDPQAVLQTMRRYVHTFFGCKECG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 EHFEEMAKESMDSVKTPDQAILWLWKKHNMVNGRLAGHLSEDPRFPKLQWPTPDLCPACH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 EHFEEMAKESMDSVKTPDQAILWLWKKHNMVNGRLAGHLSEDPRFPKLQWPTPDLCPACH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 EEIKGLASWDEGHVLTFLKQHYGRDNLLDTYSADQGDSSEGGTLARGEEEEKRLTPPEVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 EEIKGLASWDEGHVLTFLKQHYGRDNLLDTYSADQGDSSEGGTLARGEEEEKRLTPPEVS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB6 HGDRDTQSVRPPGALGPRPALPESLHHSLDGKLQSLDGPGAHKEVGGAAPFLGVDFSSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_859 HGDRDTQSVRPPGALGPRPALPESLHHSLDGKLQSLDGPGAHKEVGGAAPFLGVDFSSLD
610 620 630 640 650 660
670 680 690
pF1KB6 MSLCVVLYVASSLFLMVMYFFFRVRSRRWKVKHHHPAV
::::::::::::::::::::::::::::::::::::::
NP_859 MSLCVVLYVASSLFLMVMYFFFRVRSRRWKVKHHHPAV
670 680 690
>>NP_002817 (OMIM: 603120) sulfhydryl oxidase 1 isoform (747 aa)
initn: 1645 init1: 554 opt: 1609 Z-score: 1729.3 bits: 330.5 E(85289): 1.4e-89
Smith-Waterman score: 1617; 41.5% identity (67.6% similar) in 620 aa overlap (25-629:8-613)
10 20 30 40 50
pF1KB6 MAAAGAAVARSPGIGAGPALRARRSPPPRAARLPRLLVLLAAAAVGPGAGGAAR--LYRA
: :: : ::.:: . :::..: : :: .
NP_002 MRRCNSGSGPP-----PSLLLLLLWLLAVPGANAAPRSALY-S
10 20 30
60 70 80 90 100 110
pF1KB6 GEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVA
: . .:.. .::::. .: .:: :.:..:::::::..::::.::: ::. : :. .:
NP_002 PSDPLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLA
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB6 ALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDRELRTVRQTMIDFLQN
:::: :: :.:::.:..: .:: :.::::::. .: : ...:.:. .:: :..
NP_002 ALDCAEETNSAVCRDFNIPGFPTVRFFKAFTKN-GSGAVFPVAGADVQTLRERLIDALES
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB6 HTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVV
: . . ::::: :.: . .. ... . .:.:..::...::::::: ::: .....:
NP_002 HHD-TWPPACPPLEPAKLEEIDGFFARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAV
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB6 TRALDGDKAFLEKLGVSSVPSCYLIYPNGSHGLINVVKPLRAFFSSYLKSLPDVRKKSLP
:.:. . ..:.::.. :::::.. ::: . . :. :.:...::. : . ...
NP_002 RRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQ
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB6 LPEKPHKEENSEIVVWREFDKSKLYTVDLESGLHYLLRVELAAHKSLAGAELKTLKDFVT
: .. .::. :.::.: .::::.:::.::.:.. : : .: .:: ::.
NP_002 TTVAPTTANKIAPTVWKLADRSKIYMADLESALHYILRIEVGRFPVLEGQRLVALKKFVA
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB6 VLAKLFPGRPPVKKLLEMLQEWLASLPLDRIPYNAVLDLVNNKMRISGIFLTNHIKWVGC
:::: ::::: :...:. ..::: ..:::. ... : : :.....:.::
NP_002 VLAKYFPGRPLVQNFLHSVNEWLKRQKRNKIPYSFFKTALDD--RKEGAVLAKKVNWIGC
340 350 360 370 380 390
420 430 440 450 460 470
pF1KB6 QGSRSELRGYPCSLWKLFHTLTVEASTHPDALVGTGFEDDPQAVLQTMRRYVHTFFGCKE
:::. ..::.::::: ::: :::.:. . . . . :: ..: ::: ::::..
NP_002 QGSEPHFRGFPCSLWVLFHFLTVQAARQ--NVDHSQEAAKAKEVLPAIRGYVHYFFGCRD
400 410 420 430 440 450
480 490 500 510 520 530
pF1KB6 CGEHFEEMAKESMDSVKTPDQAILWLWKKHNMVNGRLAGHLSEDPRFPKLQWPTPDLCPA
:. :::.:: :: : .:. :.::::..:: ::.:::: ::::.:::.::: .:: :
NP_002 CASHFEQMAAASMHRVGSPNAAVLWLWSSHNRVNARLAGAPSEDPQFPKVQWPPRELCSA
460 470 480 490 500 510
540 550 560 570 580 590
pF1KB6 CHEEIKGLASWDEGHVLTFLKQHYGRDNLLDTYSA-------DQGDSSEGGTLARGEEE-
::.: . :: .:.::: :.. .:.. . : : . . . :: : :
NP_002 CHNERLDVPVWDVEATLNFLKAHFSPSNIILDFPAAGSAARRDVQNVAAAPELAMGALEL
520 530 540 550 560 570
600 610 620 630 640
pF1KB6 EKR---LTP--PEVSHGDRDTQSVRPPGALGPRPALPESLHHSLDGKLQSLDGPGAHKEV
:.: : : ::. .. .: : : ::. . : .:: .:
NP_002 ESRNSTLDPGKPEMMKSPTNTTPHVP--AEGPEASRPPKLHPGLRAAPGQEPPEHMAELQ
580 590 600 610 620
650 660 670 680 690
pF1KB6 GGAAPFLGVDFSSLDMSLCVVLYVASSLFLMVMYFFFRVRSRRWKVKHHHPAV
NP_002 RNEQEQPLGQWHLSKRDTGAALLAESRAEKNRLWGPLEVRRVGRSSKQLVDIPEGQLEAR
630 640 650 660 670 680
>>NP_001004128 (OMIM: 603120) sulfhydryl oxidase 1 isofo (604 aa)
initn: 1531 init1: 554 opt: 1587 Z-score: 1706.9 bits: 326.1 E(85289): 2.5e-88
Smith-Waterman score: 1596; 41.1% identity (68.7% similar) in 603 aa overlap (25-624:8-588)
10 20 30 40 50
pF1KB6 MAAAGAAVARSPGIGAGPALRARRSPPPRAARLPRLLVLLAAAAVGPGAGGAAR--LYRA
: :: : ::.:: . :::..: : :: .
NP_001 MRRCNSGSGPP-----PSLLLLLLWLLAVPGANAAPRSALY-S
10 20 30
60 70 80 90 100 110
pF1KB6 GEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVA
: . .:.. .::::. .: .:: :.:..:::::::..::::.::: ::. : :. .:
NP_001 PSDPLTLLQADTVRGAVLGSRSAWAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLA
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB6 ALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDRELRTVRQTMIDFLQN
:::: :: :.:::.:..: .:: :.::::::. .: : ...:.:. .:: :..
NP_001 ALDCAEETNSAVCRDFNIPGFPTVRFFKAFTKN-GSGAVFPVAGADVQTLRERLIDALES
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB6 HTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVV
: . . ::::: :.: . .. ... . .:.:..::...::::::: ::: .....:
NP_001 HHD-TWPPACPPLEPAKLEEIDGFFARNNEEYLALIFEKGGSYLGREVALDLSQHKGVAV
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB6 TRALDGDKAFLEKLGVSSVPSCYLIYPNGSHGLINVVKPLRAFFSSYLKSLPDVRKKSLP
:.:. . ..:.::.. :::::.. ::: . . :. :.:...::. : . ...
NP_001 RRVLNTEANVVRKFGVTDFPSCYLLFRNGSVSRVPVLMESRSFYTAYLQRLSGLTREAAQ
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB6 LPEKPHKEENSEIVVWREFDKSKLYTVDLESGLHYLLRVELAAHKSLAGAELKTLKDFVT
: .. .::. :.::.: .::::.:::.::.:.. : : .: .:: ::.
NP_001 TTVAPTTANKIAPTVWKLADRSKIYMADLESALHYILRIEVGRFPVLEGQRLVALKKFVA
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB6 VLAKLFPGRPPVKKLLEMLQEWLASLPLDRIPYNAVLDLVNNKMRISGIFLTNHIKWVGC
:::: ::::: :...:. ..::: ..:::. ... : : :.....:.::
NP_001 VLAKYFPGRPLVQNFLHSVNEWLKRQKRNKIPYSFFKTALDD--RKEGAVLAKKVNWIGC
340 350 360 370 380 390
420 430 440 450 460 470
pF1KB6 QGSRSELRGYPCSLWKLFHTLTVEASTHPDALVGTGFEDDPQAVLQTMRRYVHTFFGCKE
:::. ..::.::::: ::: :::.:. . . . . :: ..: ::: ::::..
NP_001 QGSEPHFRGFPCSLWVLFHFLTVQAARQ--NVDHSQEAAKAKEVLPAIRGYVHYFFGCRD
400 410 420 430 440 450
480 490 500 510 520 530
pF1KB6 CGEHFEEMAKESMDSVKTPDQAILWLWKKHNMVNGRLAGHLSEDPRFPKLQWPTPDLCPA
:. :::.:: :: : .:. :.::::..:: ::.:::: ::::.:::.::: .:: :
NP_001 CASHFEQMAAASMHRVGSPNAAVLWLWSSHNRVNARLAGAPSEDPQFPKVQWPPRELCSA
460 470 480 490 500 510
540 550 560 570 580 590
pF1KB6 CHEEIKGLASWDEGHVLTFLKQHYGRDNLLDTYSADQGDSSEGGTLARGEEEEKRLTPPE
::.: . :: .:.::: :.. .:.. . : .:. :: .. .. . ::
NP_001 CHNERLDVPVWDVEATLNFLKAHFSPSNIILDFPA-------AGSAAR-RDVQNVAAAPE
520 530 540 550 560
600 610 620 630 640 650
pF1KB6 VSHGDRDTQSVRPPGALGP-RPALPESLHHSLDGKLQSLDGPGAHKEVGGAAPFLGVDFS
.. : . .: ..: : .: . .:
NP_001 LAMGALELESRN--STLDPGKPEMMKSPTNTTPHVPAEGPELI
570 580 590 600
>>XP_011508610 (OMIM: 611099) PREDICTED: protein disulfi (402 aa)
initn: 131 init1: 106 opt: 228 Z-score: 245.5 bits: 55.1 E(85289): 6.2e-07
Smith-Waterman score: 228; 27.7% identity (60.0% similar) in 155 aa overlap (55-205:20-168)
30 40 50 60 70 80
pF1KB6 SPPPRAARLPRLLVLLAAAAVGPGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLV
:: ...:.. . :. : . .:.. :::
XP_011 MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNR-EVIQSDSLWLV
10 20 30 40
90 100 110 120 130 140
pF1KB6 QFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRY
.::. ::::: .: :. : ..: ...:.:.: .:.... .: .. .::..
XP_011 EFYAPWCGHCQRLTPEWKKAATALKD---VVKVGAVDA--DKHHSLGGQYGVQGFPTIKI
50 60 70 80 90 100
150 160 170 180 190 200
pF1KB6 F---KAFTKEFTTGENFKGP-DRELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVL
: : ... :.. .. : : ..:: . : : ... : : : . .::.
XP_011 FGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVI
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB6 SLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVVTRALDGDKAFLEKLGVSSVPSC
: :.
XP_011 ELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT
170 180 190 200 210 220
>--
initn: 153 init1: 104 opt: 186 Z-score: 200.2 bits: 46.7 E(85289): 0.00021
Smith-Waterman score: 186; 35.2% identity (69.0% similar) in 71 aa overlap (77-146:176-244)
50 60 70 80 90 100
pF1KB6 PGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAG
.: .:.:.::. ::::: . : : : :.
XP_011 YSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAAS
150 160 170 180 190 200
110 120 130 140 150 160
pF1KB6 DVRDWASA-IRVAALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDREL
.:.. ... ...::.: ::.. : :. .::.. :.
XP_011 EVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS
210 220 230 240 250 260
170 180 190 200 210 220
pF1KB6 RTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGRE
XP_011 RALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKL
270 280 290 300 310 320
>>NP_001269636 (OMIM: 611099) protein disulfide-isomeras (437 aa)
initn: 131 init1: 106 opt: 228 Z-score: 244.9 bits: 55.1 E(85289): 6.6e-07
Smith-Waterman score: 228; 27.7% identity (60.0% similar) in 155 aa overlap (55-205:17-165)
30 40 50 60 70 80
pF1KB6 SPPPRAARLPRLLVLLAAAAVGPGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLV
:: ...:.. . :. : . .:.. :::
NP_001 MILGLVSCTFFLAVNGLYSSSDDVIELTPSNFNR-EVIQSDSLWLV
10 20 30 40
90 100 110 120 130 140
pF1KB6 QFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRY
.::. ::::: .: :. : ..: ...:.:.: .:.... .: .. .::..
NP_001 EFYAPWCGHCQRLTPEWKKAATALKD---VVKVGAVDA--DKHHSLGGQYGVQGFPTIKI
50 60 70 80 90 100
150 160 170 180 190 200
pF1KB6 F---KAFTKEFTTGENFKGP-DRELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVL
: : ... :.. .. : : ..:: . : : ... : : : . .::.
NP_001 FGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVI
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB6 SLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVVTRALDGDKAFLEKLGVSSVPSC
: :.
NP_001 ELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT
170 180 190 200 210 220
>--
initn: 157 init1: 104 opt: 186 Z-score: 199.7 bits: 46.7 E(85289): 0.00022
Smith-Waterman score: 186; 35.2% identity (69.0% similar) in 71 aa overlap (77-146:173-241)
50 60 70 80 90 100
pF1KB6 PGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAG
.: .:.:.::. ::::: . : : : :.
NP_001 YSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAAS
150 160 170 180 190 200
110 120 130 140 150 160
pF1KB6 DVRDWASA-IRVAALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDREL
.:.. ... ...::.: ::.. : :. .::.. :.
NP_001 EVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS
210 220 230 240 250 260
170 180 190 200 210 220
pF1KB6 RTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGRE
NP_001 RALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKL
270 280 290 300 310 320
>>NP_005733 (OMIM: 611099) protein disulfide-isomerase A (440 aa)
initn: 131 init1: 106 opt: 228 Z-score: 244.9 bits: 55.1 E(85289): 6.7e-07
Smith-Waterman score: 228; 27.7% identity (60.0% similar) in 155 aa overlap (55-205:20-168)
30 40 50 60 70 80
pF1KB6 SPPPRAARLPRLLVLLAAAAVGPGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLV
:: ...:.. . :. : . .:.. :::
NP_005 MALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNR-EVIQSDSLWLV
10 20 30 40
90 100 110 120 130 140
pF1KB6 QFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRY
.::. ::::: .: :. : ..: ...:.:.: .:.... .: .. .::..
NP_005 EFYAPWCGHCQRLTPEWKKAATALKD---VVKVGAVDA--DKHHSLGGQYGVQGFPTIKI
50 60 70 80 90 100
150 160 170 180 190 200
pF1KB6 F---KAFTKEFTTGENFKGP-DRELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVL
: : ... :.. .. : : ..:: . : : ... : : : . .::.
NP_005 FGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVI
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB6 SLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVVTRALDGDKAFLEKLGVSSVPSC
: :.
NP_005 ELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT
170 180 190 200 210 220
>--
initn: 157 init1: 104 opt: 186 Z-score: 199.6 bits: 46.8 E(85289): 0.00022
Smith-Waterman score: 186; 35.2% identity (69.0% similar) in 71 aa overlap (77-146:176-244)
50 60 70 80 90 100
pF1KB6 PGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAG
.: .:.:.::. ::::: . : : : :.
NP_005 YSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAAS
150 160 170 180 190 200
110 120 130 140 150 160
pF1KB6 DVRDWASA-IRVAALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDREL
.:.. ... ...::.: ::.. : :. .::.. :.
NP_005 EVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS
210 220 230 240 250 260
170 180 190 200 210 220
pF1KB6 RTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGRE
NP_005 RALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKL
270 280 290 300 310 320
>>NP_001269635 (OMIM: 611099) protein disulfide-isomeras (445 aa)
initn: 131 init1: 106 opt: 228 Z-score: 244.8 bits: 55.1 E(85289): 6.7e-07
Smith-Waterman score: 228; 27.7% identity (60.0% similar) in 155 aa overlap (55-205:25-173)
30 40 50 60 70 80
pF1KB6 SPPPRAARLPRLLVLLAAAAVGPGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLV
:: ...:.. . :. : . .:.. :::
NP_001 MYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELTPSNFNR-EVIQSDSLWLV
10 20 30 40 50
90 100 110 120 130 140
pF1KB6 QFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRY
.::. ::::: .: :. : ..: ...:.:.: .:.... .: .. .::..
NP_001 EFYAPWCGHCQRLTPEWKKAATALKD---VVKVGAVDA--DKHHSLGGQYGVQGFPTIKI
60 70 80 90 100
150 160 170 180 190 200
pF1KB6 F---KAFTKEFTTGENFKGP-DRELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVL
: : ... :.. .. : : ..:: . : : ... : : : . .::.
NP_001 FGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVI
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB6 SLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVVTRALDGDKAFLEKLGVSSVPSC
: :.
NP_001 ELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT
170 180 190 200 210 220
>--
initn: 157 init1: 104 opt: 186 Z-score: 199.6 bits: 46.8 E(85289): 0.00022
Smith-Waterman score: 186; 35.2% identity (69.0% similar) in 71 aa overlap (77-146:181-249)
50 60 70 80 90 100
pF1KB6 PGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAG
.: .:.:.::. ::::: . : : : :.
NP_001 YSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAAS
160 170 180 190 200 210
110 120 130 140 150 160
pF1KB6 DVRDWASA-IRVAALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDREL
.:.. ... ...::.: ::.. : :. .::.. :.
NP_001 EVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS
220 230 240 250 260
170 180 190 200 210 220
pF1KB6 RTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGRE
NP_001 RALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKL
270 280 290 300 310 320
>>NP_001269634 (OMIM: 611099) protein disulfide-isomeras (488 aa)
initn: 131 init1: 106 opt: 228 Z-score: 244.2 bits: 55.2 E(85289): 7.3e-07
Smith-Waterman score: 228; 27.7% identity (60.0% similar) in 155 aa overlap (55-205:68-216)
30 40 50 60 70 80
pF1KB6 SPPPRAARLPRLLVLLAAAAVGPGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLV
:: ...:.. . :. : . .:.. :::
NP_001 SRKSPIMYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELTPSNFNR-EVIQSDSLWLV
40 50 60 70 80 90
90 100 110 120 130 140
pF1KB6 QFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRY
.::. ::::: .: :. : ..: ...:.:.: .:.... .: .. .::..
NP_001 EFYAPWCGHCQRLTPEWKKAATALKD---VVKVGAVDA--DKHHSLGGQYGVQGFPTIKI
100 110 120 130 140 150
150 160 170 180 190 200
pF1KB6 F---KAFTKEFTTGENFKGP-DRELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVL
: : ... :.. .. : : ..:: . : : ... : : : . .::.
NP_001 FGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVI
160 170 180 190 200 210
210 220 230 240 250 260
pF1KB6 SLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVVTRALDGDKAFLEKLGVSSVPSC
: :.
NP_001 ELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT
220 230 240 250 260 270
>--
initn: 157 init1: 104 opt: 186 Z-score: 199.0 bits: 46.8 E(85289): 0.00024
Smith-Waterman score: 186; 35.2% identity (69.0% similar) in 71 aa overlap (77-146:224-292)
50 60 70 80 90 100
pF1KB6 PGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAG
.: .:.:.::. ::::: . : : : :.
NP_001 YSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAAS
200 210 220 230 240 250
110 120 130 140 150 160
pF1KB6 DVRDWASA-IRVAALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDREL
.:.. ... ...::.: ::.. : :. .::.. :.
NP_001 EVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS
260 270 280 290 300 310
170 180 190 200 210 220
pF1KB6 RTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGRE
NP_001 RALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKL
320 330 340 350 360 370
>>NP_001269633 (OMIM: 611099) protein disulfide-isomeras (492 aa)
initn: 131 init1: 106 opt: 228 Z-score: 244.2 bits: 55.2 E(85289): 7.3e-07
Smith-Waterman score: 228; 27.7% identity (60.0% similar) in 155 aa overlap (55-205:72-220)
30 40 50 60 70 80
pF1KB6 SPPPRAARLPRLLVLLAAAAVGPGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLV
:: ...:.. . :. : . .:.. :::
NP_001 SRKSPIMYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELTPSNFNR-EVIQSDSLWLV
50 60 70 80 90 100
90 100 110 120 130 140
pF1KB6 QFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRY
.::. ::::: .: :. : ..: ...:.:.: .:.... .: .. .::..
NP_001 EFYAPWCGHCQRLTPEWKKAATALKD---VVKVGAVDA--DKHHSLGGQYGVQGFPTIKI
110 120 130 140 150
150 160 170 180 190 200
pF1KB6 F---KAFTKEFTTGENFKGP-DRELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVL
: : ... :.. .. : : ..:: . : : ... : : : . .::.
NP_001 FGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSSGKQGRSDSSSKKDVI
160 170 180 190 200 210
210 220 230 240 250 260
pF1KB6 SLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVVTRALDGDKAFLEKLGVSSVPSC
: :.
NP_001 ELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAVDAT
220 230 240 250 260 270
>--
initn: 157 init1: 104 opt: 186 Z-score: 198.9 bits: 46.8 E(85289): 0.00024
Smith-Waterman score: 186; 35.2% identity (69.0% similar) in 71 aa overlap (77-146:228-296)
50 60 70 80 90 100
pF1KB6 PGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAG
.: .:.:.::. ::::: . : : : :.
NP_001 YSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAAS
200 210 220 230 240 250
110 120 130 140 150 160
pF1KB6 DVRDWASA-IRVAALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDREL
.:.. ... ...::.: ::.. : :. .::.. :.
NP_001 EVKEQTKGKVKLAAVDAT--VNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS
260 270 280 290 300 310
170 180 190 200 210 220
pF1KB6 RTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGRE
NP_001 RALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKL
320 330 340 350 360 370
>>NP_000909 (OMIM: 112240,176790) protein disulfide-isom (508 aa)
initn: 180 init1: 150 opt: 207 Z-score: 221.4 bits: 51.0 E(85289): 1.4e-05
Smith-Waterman score: 207; 38.0% identity (63.0% similar) in 100 aa overlap (60-155:23-119)
30 40 50 60 70 80
pF1KB6 AARLPRLLVLLAAAAVGPGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSS
:: : :: ... : : . ::.::.
NP_000 MLRRALLCLAVAALVRADAPEEEDHVLVLRKSNFAEALA-AHKYLLVEFYAP
10 20 30 40 50
90 100 110 120 130 140
pF1KB6 WCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRYFK---
::::: . :: . :: .. .: ::.: .: ::.. : ..: .. :::...:.
NP_000 WCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLA--QQYGVRGYPTIKFFRNGD
60 70 80 90 100
150 160 170 180 190 200
pF1KB6 -AFTKEFTTGENFKGPDRELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDN
: ::.:.:
NP_000 TASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDVESDSA
110 120 130 140 150 160
698 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:22:09 2016 done: Sat Nov 5 07:22:11 2016
Total Scan time: 12.920 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]