Result of FASTA (omim) for
pFN21AE9543
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE9543, 496 aa
1>>>pF1KE9543 496 - 496 aa - 496 aa
Library: /omim/omim.rfq.tfa
64369986 residues in 92320 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0390+/-0.000428; mu= 19.3222+/- 0.026
mean_var=68.6856+/-14.472, 0's: 0 Z-trim(110.9): 310 B-trim: 1458 in 2/51
Lambda= 0.154754
statistics sampled from 19806 (20145) to 19806 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.582), E-opt: 0.2 (0.218), width: 16
Scan time: 4.540
The best scores are: opt bits E(92320)
NP_001186564 (OMIM: 102981) pituitary adenylate cy ( 496) 3427 774.8 0
NP_001186565 (OMIM: 102981) pituitary adenylate cy ( 495) 3410 771.0 0
XP_016867225 (OMIM: 102981) pituitary adenylate cy ( 489) 3356 758.9 0
XP_006715708 (OMIM: 102981) pituitary adenylate cy ( 496) 3214 727.2 2.8e-209
XP_016867227 (OMIM: 102981) pituitary adenylate cy ( 439) 2671 605.9 7.9e-173
XP_016867226 (OMIM: 102981) pituitary adenylate cy ( 475) 2660 603.5 4.6e-172
NP_001109 (OMIM: 102981) pituitary adenylate cycla ( 468) 2443 555.1 1.8e-157
XP_005249675 (OMIM: 102981) pituitary adenylate cy ( 411) 1687 386.2 1e-106
NP_001186566 (OMIM: 102981) pituitary adenylate cy ( 447) 1676 383.8 6e-106
XP_024302684 (OMIM: 601970) vasoactive intestinal ( 438) 989 230.4 8.8e-60
XP_024302683 (OMIM: 601970) vasoactive intestinal ( 463) 989 230.4 9.1e-60
XP_024302682 (OMIM: 601970) vasoactive intestinal ( 463) 989 230.4 9.1e-60
NP_003373 (OMIM: 601970) vasoactive intestinal pol ( 438) 987 230.0 1.2e-59
XP_006716170 (OMIM: 601970) vasoactive intestinal ( 455) 987 230.0 1.2e-59
XP_005249618 (OMIM: 601970) vasoactive intestinal ( 463) 987 230.0 1.2e-59
XP_024302685 (OMIM: 601970) vasoactive intestinal ( 375) 984 229.2 1.7e-59
XP_006716171 (OMIM: 601970) vasoactive intestinal ( 392) 984 229.3 1.7e-59
NP_001238813 (OMIM: 192321) vasoactive intestinal ( 409) 927 216.5 1.2e-55
XP_005265494 (OMIM: 192321) vasoactive intestinal ( 456) 927 216.6 1.3e-55
XP_011532382 (OMIM: 192321) vasoactive intestinal ( 351) 916 214.0 5.9e-55
XP_005265496 (OMIM: 192321) vasoactive intestinal ( 410) 916 214.1 6.7e-55
XP_011532381 (OMIM: 192321) vasoactive intestinal ( 416) 916 214.1 6.8e-55
XP_005265495 (OMIM: 192321) vasoactive intestinal ( 416) 916 214.1 6.8e-55
NP_001238811 (OMIM: 192321) vasoactive intestinal ( 416) 916 214.1 6.8e-55
NP_001238814 (OMIM: 192321) vasoactive intestinal ( 430) 916 214.1 7e-55
XP_024308806 (OMIM: 182098) secretin receptor isof ( 372) 915 213.8 7.3e-55
NP_004615 (OMIM: 192321) vasoactive intestinal pol ( 457) 916 214.1 7.3e-55
NP_002971 (OMIM: 182098) secretin receptor precurs ( 440) 915 213.9 8.3e-55
XP_016860160 (OMIM: 182098) secretin receptor isof ( 409) 900 210.5 8e-54
XP_016860161 (OMIM: 182098) secretin receptor isof ( 377) 895 209.4 1.6e-53
XP_016860159 (OMIM: 182098) secretin receptor isof ( 435) 895 209.4 1.8e-53
XP_011509923 (OMIM: 182098) secretin receptor isof ( 445) 895 209.4 1.8e-53
NP_001295188 (OMIM: 601970) vasoactive intestinal ( 422) 849 199.1 2.2e-50
XP_011514852 (OMIM: 601970) vasoactive intestinal ( 439) 849 199.2 2.3e-50
XP_024302686 (OMIM: 601970) vasoactive intestinal ( 300) 775 182.5 1.6e-45
XP_016868069 (OMIM: 601970) vasoactive intestinal ( 300) 775 182.5 1.6e-45
NP_000814 (OMIM: 139191,618157) growth hormone-rel ( 423) 756 178.4 3.9e-44
XP_005263787 (OMIM: 182098) secretin receptor isof ( 262) 616 147.0 6.9e-35
NP_001295347 (OMIM: 137241) gastric inhibitory pol ( 430) 611 146.0 2.2e-34
NP_000155 (OMIM: 137241) gastric inhibitory polype ( 466) 611 146.0 2.3e-34
XP_016860162 (OMIM: 182098) secretin receptor isof ( 267) 596 142.5 1.5e-33
NP_001291451 (OMIM: 601970) vasoactive intestinal ( 358) 556 133.7 9.5e-31
XP_011525013 (OMIM: 137241) gastric inhibitory pol ( 472) 554 133.3 1.6e-30
XP_011525012 (OMIM: 137241) gastric inhibitory pol ( 508) 554 133.3 1.7e-30
XP_011525011 (OMIM: 137241) gastric inhibitory pol ( 508) 554 133.3 1.7e-30
XP_011525016 (OMIM: 137241) gastric inhibitory pol ( 369) 516 124.8 4.7e-28
XP_011525017 (OMIM: 137241) gastric inhibitory pol ( 369) 516 124.8 4.7e-28
NP_001238812 (OMIM: 192321) vasoactive intestinal ( 247) 454 110.8 5.1e-24
NP_001733 (OMIM: 114131,166710) calcitonin recepto ( 474) 445 109.0 3.4e-23
NP_001158210 (OMIM: 114131,166710) calcitonin rece ( 474) 445 109.0 3.4e-23
>>NP_001186564 (OMIM: 102981) pituitary adenylate cyclas (496 aa)
initn: 3427 init1: 3427 opt: 3427 Z-score: 4135.9 bits: 774.8 E(92320): 0
Smith-Waterman score: 3427; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496)
10 20 30 40 50 60
pF1KE9 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYFSCVQKCYCKPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYFSCVQKCYCKPQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 RAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
430 440 450 460 470 480
490
pF1KE9 SSQIRMSGLPADNLAT
::::::::::::::::
NP_001 SSQIRMSGLPADNLAT
490
>>NP_001186565 (OMIM: 102981) pituitary adenylate cyclas (495 aa)
initn: 2450 init1: 2450 opt: 3410 Z-score: 4115.4 bits: 771.0 E(92320): 0
Smith-Waterman score: 3410; 99.8% identity (99.8% similar) in 496 aa overlap (1-496:1-495)
10 20 30 40 50 60
pF1KE9 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYFSCVQKCYCKPQ
::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::
NP_001 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYF-CVQKCYCKPQ
310 320 330 340 350
370 380 390 400 410 420
pF1KE9 RAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE9 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
420 430 440 450 460 470
490
pF1KE9 SSQIRMSGLPADNLAT
::::::::::::::::
NP_001 SSQIRMSGLPADNLAT
480 490
>>XP_016867225 (OMIM: 102981) pituitary adenylate cyclas (489 aa)
initn: 3366 init1: 2750 opt: 3356 Z-score: 4050.3 bits: 758.9 E(92320): 0
Smith-Waterman score: 3356; 98.6% identity (98.6% similar) in 496 aa overlap (1-496:1-489)
10 20 30 40 50 60
pF1KE9 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE
:::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_016 ITCWKPAHVGEMVLVSCPELFRIFNPDQ-------GESDFGDSNSLDLSDMGVVSRNCTE
70 80 90 100 110
130 140 150 160 170 180
pF1KE9 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE9 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE9 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE9 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYFSCVQKCYCKPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYFSCVQKCYCKPQ
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE9 RAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE9 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
420 430 440 450 460 470
490
pF1KE9 SSQIRMSGLPADNLAT
::::::::::::::::
XP_016 SSQIRMSGLPADNLAT
480
>>XP_006715708 (OMIM: 102981) pituitary adenylate cyclas (496 aa)
initn: 3214 init1: 3214 opt: 3214 Z-score: 3878.9 bits: 727.2 E(92320): 2.8e-209
Smith-Waterman score: 3214; 95.0% identity (96.4% similar) in 496 aa overlap (1-496:1-496)
10 20 30 40 50 60
pF1KE9 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYFSCVQKCYCKPQ
::::::::::::::::::::::::::::::::::::::::::::::::.. .. :
XP_006 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLTNLSPRVPKKA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE9 RAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
: . .. : ::::::::::::::::::::::::::::::::::::::::::::
XP_006 REDPLPVPSDQHSLPFLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE9 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
430 440 450 460 470 480
490
pF1KE9 SSQIRMSGLPADNLAT
::::::::::::::::
XP_006 SSQIRMSGLPADNLAT
490
>>XP_016867227 (OMIM: 102981) pituitary adenylate cyclas (439 aa)
initn: 2664 init1: 2664 opt: 2671 Z-score: 3224.4 bits: 605.9 E(92320): 7.9e-173
Smith-Waterman score: 2880; 88.5% identity (88.5% similar) in 496 aa overlap (1-496:1-439)
10 20 30 40 50 60
pF1KE9 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSP--------
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE
:::::::::::
XP_016 -------------------------------------------------DMGVVSRNCTE
60
130 140 150 160 170 180
pF1KE9 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
70 80 90 100 110 120
190 200 210 220 230 240
pF1KE9 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE9 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
190 200 210 220 230 240
310 320 330 340 350 360
pF1KE9 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYFSCVQKCYCKPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYFSCVQKCYCKPQ
250 260 270 280 290 300
370 380 390 400 410 420
pF1KE9 RAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
310 320 330 340 350 360
430 440 450 460 470 480
pF1KE9 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
370 380 390 400 410 420
490
pF1KE9 SSQIRMSGLPADNLAT
::::::::::::::::
XP_016 SSQIRMSGLPADNLAT
430
>>XP_016867226 (OMIM: 102981) pituitary adenylate cyclas (475 aa)
initn: 3275 init1: 2659 opt: 2660 Z-score: 3210.7 bits: 603.5 E(92320): 4.6e-172
Smith-Waterman score: 3237; 95.8% identity (95.8% similar) in 496 aa overlap (1-496:1-475)
10 20 30 40 50 60
pF1KE9 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE
:::::::::::::::::::::::::::: :::::::::::
XP_016 ITCWKPAHVGEMVLVSCPELFRIFNPDQ---------------------DMGVVSRNCTE
70 80 90
130 140 150 160 170 180
pF1KE9 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE9 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE9 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE9 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYFSCVQKCYCKPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYFSCVQKCYCKPQ
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE9 RAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE9 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
400 410 420 430 440 450
490
pF1KE9 SSQIRMSGLPADNLAT
::::::::::::::::
XP_016 SSQIRMSGLPADNLAT
460 470
>>NP_001109 (OMIM: 102981) pituitary adenylate cyclase-a (468 aa)
initn: 2443 init1: 2443 opt: 2443 Z-score: 2948.9 bits: 555.1 E(92320): 1.8e-157
Smith-Waterman score: 3157; 94.4% identity (94.4% similar) in 496 aa overlap (1-496:1-468)
10 20 30 40 50 60
pF1KE9 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE9 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE9 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE9 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE9 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYFSCVQKCYCKPQ
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIY------------
310 320 330 340
370 380 390 400 410 420
pF1KE9 RAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----------------LRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
350 360 370 380 390
430 440 450 460 470 480
pF1KE9 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
400 410 420 430 440 450
490
pF1KE9 SSQIRMSGLPADNLAT
::::::::::::::::
NP_001 SSQIRMSGLPADNLAT
460
>>XP_005249675 (OMIM: 102981) pituitary adenylate cyclas (411 aa)
initn: 1680 init1: 1680 opt: 1687 Z-score: 2037.5 bits: 386.2 E(92320): 1e-106
Smith-Waterman score: 2610; 82.9% identity (82.9% similar) in 496 aa overlap (1-496:1-411)
10 20 30 40 50 60
pF1KE9 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSP--------
10 20 30 40 50
70 80 90 100 110 120
pF1KE9 ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE
:::::::::::
XP_005 -------------------------------------------------DMGVVSRNCTE
60
130 140 150 160 170 180
pF1KE9 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
70 80 90 100 110 120
190 200 210 220 230 240
pF1KE9 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
130 140 150 160 170 180
250 260 270 280 290 300
pF1KE9 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
190 200 210 220 230 240
310 320 330 340 350 360
pF1KE9 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYFSCVQKCYCKPQ
::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIY------------
250 260 270 280 290
370 380 390 400 410 420
pF1KE9 RAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
::::::::::::::::::::::::::::::::::::::::::::
XP_005 ----------------LRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
300 310 320 330
430 440 450 460 470 480
pF1KE9 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
340 350 360 370 380 390
490
pF1KE9 SSQIRMSGLPADNLAT
::::::::::::::::
XP_005 SSQIRMSGLPADNLAT
400 410
>>NP_001186566 (OMIM: 102981) pituitary adenylate cyclas (447 aa)
initn: 2291 init1: 1675 opt: 1676 Z-score: 2023.7 bits: 383.8 E(92320): 6e-106
Smith-Waterman score: 2967; 90.1% identity (90.1% similar) in 496 aa overlap (1-496:1-447)
10 20 30 40 50 60
pF1KE9 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE9 ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE
:::::::::::::::::::::::::::: :::::::::::
NP_001 ITCWKPAHVGEMVLVSCPELFRIFNPDQ---------------------DMGVVSRNCTE
70 80 90
130 140 150 160 170 180
pF1KE9 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE9 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE9 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE9 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYFSCVQKCYCKPQ
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIY------------
280 290 300 310 320
370 380 390 400 410 420
pF1KE9 RAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----------------LRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQ
330 340 350 360 370
430 440 450 460 470 480
pF1KE9 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKS
380 390 400 410 420 430
490
pF1KE9 SSQIRMSGLPADNLAT
::::::::::::::::
NP_001 SSQIRMSGLPADNLAT
440
>>XP_024302684 (OMIM: 601970) vasoactive intestinal poly (438 aa)
initn: 1230 init1: 463 opt: 989 Z-score: 1194.9 bits: 230.4 E(92320): 8.8e-60
Smith-Waterman score: 1270; 49.1% identity (72.1% similar) in 405 aa overlap (82-482:56-429)
60 70 80 90 100 110
pF1KE9 PGCPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETE-TIGESDFGDSNSLDLSD
: : :.. : . : : . ... ..
XP_024 LPKSLQQFLQQSRYCPSVEFLSSSRVFASERPFFPSKKQEHHFPSGISCYPGGQGTAVAY
30 40 50 60 70 80
120 130 140 150 160 170
pF1KE9 MGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTT
: .:.::: ::::: :: . ::::... :.:. . .:. :::.::.:::.::..:.:
XP_024 WGNISKNCTSDGWSETFPDFVDACGYSDPEDES--KITFYILVKAIYTLGYSVSLMSLAT
90 100 110 120 130 140
180 190 200 210 220
pF1KE9 AMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCF---ISTVECK
. .::: :::::::::.::.:::.::.::::::..:: .::. . . :: : : ::
XP_024 GSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCK
150 160 170 180 190 200
230 240 250 260 270 280
pF1KE9 AVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATL
.::..::...:.:::..::::: :::: ...: :: : : .:::: ::::. .:..
XP_024 LSLVFLQYCIMANFFWLLVEGLYLHTLLV-AMLPPRRCFLAYLLIGWGLPTVCIGAWTAA
210 220 230 240 250 260
290 300 310 320 330 340
pF1KE9 RLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSI
:::..:::::: :: .. ::::. :.. ::.:::::::.:: ::.::: :::.:::..:
XP_024 RLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQ
270 280 290 300 310 320
350 360 370 380 390 400
pF1KE9 YFSCVQKCYCKPQRAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPENVSKR
: :::.::::::::::.:: ::: : ..:..
XP_024 Y----------------------------KRLAKSTLLLIPLFGVHYMVFAVFPISISSK
330 340 350
410 420 430 440 450 460
pF1KE9 ERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSG
...::: ::::::.::::::::::.::: :.:::::: . . :.. :.. .:
XP_024 YQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASRDYRVCGSSFSRNG
360 370 380 390 400 410
470 480 490
pF1KE9 VNGGTQLSILSKSSSQIRMSGLPADNLAT
.:. :. :...:
XP_024 SEGALQFHRGSRAQSFLQTETSVI
420 430
496 residues in 1 query sequences
64369986 residues in 92320 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Oct 24 21:55:23 2019 done: Thu Oct 24 21:55:24 2019
Total Scan time: 4.540 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]