Result of FASTA (omim) for
pFN21AB5161
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5161, 463 aa
1>>>pF1KB5161 463 - 463 aa - 463 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5544+/-0.000466; mu= 16.3241+/- 0.029
mean_var=64.0712+/-13.101, 0's: 0 Z-trim(109.6): 20 B-trim: 254 in 1/49
Lambda= 0.160230
statistics sampled from 17755 (17772) to 17755 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.563), E-opt: 0.2 (0.208), width: 16
Scan time: 9.050
The best scores are: opt bits E(85289)
NP_003841 (OMIM: 603921,612073) succinate--CoA lig ( 463) 2968 695.2 9.4e-200
XP_016876295 (OMIM: 603921,612073) PREDICTED: succ ( 405) 2593 608.5 1e-173
XP_016876296 (OMIM: 603921,612073) PREDICTED: succ ( 384) 2396 563.0 5.1e-160
XP_016876298 (OMIM: 603921,612073) PREDICTED: succ ( 329) 2122 499.6 5.2e-141
XP_016876297 (OMIM: 603921,612073) PREDICTED: succ ( 344) 1709 404.2 2.9e-112
NP_003839 (OMIM: 603922) succinate--CoA ligase [GD ( 432) 1357 322.8 1.1e-87
XP_016862908 (OMIM: 603922) PREDICTED: succinyl-Co ( 433) 1290 307.3 5.2e-83
NP_001171070 (OMIM: 603922) succinate--CoA ligase ( 440) 1290 307.3 5.3e-83
XP_016862907 (OMIM: 603922) PREDICTED: succinyl-Co ( 445) 1290 307.3 5.3e-83
XP_016862906 (OMIM: 603922) PREDICTED: succinyl-Co ( 457) 1290 307.3 5.4e-83
XP_016862905 (OMIM: 603922) PREDICTED: succinyl-Co ( 458) 1290 307.3 5.4e-83
XP_016862904 (OMIM: 603922) PREDICTED: succinyl-Co ( 480) 1290 307.4 5.7e-83
XP_016862909 (OMIM: 603922) PREDICTED: succinyl-Co ( 408) 1285 306.2 1.1e-82
>>NP_003841 (OMIM: 603921,612073) succinate--CoA ligase (463 aa)
initn: 2968 init1: 2968 opt: 2968 Z-score: 3707.2 bits: 695.2 E(85289): 9.4e-200
Smith-Waterman score: 2968; 99.8% identity (100.0% similar) in 463 aa overlap (1-463:1-463)
10 20 30 40 50 60
pF1KB5 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGLFNNHGLQVQQQQQRNLSLHEYMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGLFNNHGLQVQQQQQRNLSLHEYMS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 MELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 IVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 VLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAENM
::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
NP_003 VLIGSSHGGVNIEDVAAESPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAENM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 VKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDER
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 DKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTEA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 FKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDAKALI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDAKALI
370 380 390 400 410 420
430 440 450 460
pF1KB5 ADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
:::::::::::::::::::::::::::::::::::::::::::
NP_003 ADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
430 440 450 460
>>XP_016876295 (OMIM: 603921,612073) PREDICTED: succinyl (405 aa)
initn: 2593 init1: 2593 opt: 2593 Z-score: 3239.6 bits: 608.5 E(85289): 1e-173
Smith-Waterman score: 2593; 99.8% identity (100.0% similar) in 405 aa overlap (59-463:1-405)
30 40 50 60 70 80
pF1KB5 AQVLGSSGLFNNHGLQVQQQQQRNLSLHEYMSMELLQEAGVSVPKGYVAKSPDEAYAIAK
::::::::::::::::::::::::::::::
XP_016 MSMELLQEAGVSVPKGYVAKSPDEAYAIAK
10 20 30
90 100 110 120 130 140
pF1KB5 KLGSKDVVIKAQVLAGGRGKGTFESGLKGGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLGSKDVVIKAQVLAGGRGKGTFESGLKGGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEK
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB5 GRICNQVLVCERKYPRREYYFAITMERSFQGPVLIGSSHGGVNIEDVAAETPEAIIKEPI
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
XP_016 GRICNQVLVCERKYPRREYYFAITMERSFQGPVLIGSSHGGVNIEDVAAESPEAIIKEPI
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB5 DIEEGIKKEQALQLAQKMGFPPNIVESAAENMVKLYSLFLKYDATMIEINPMVEDSDGAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIEEGIKKEQALQLAQKMGFPPNIVESAAENMVKLYSLFLKYDATMIEINPMVEDSDGAV
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB5 LCMDAKINFDSNSAYRQKKIFDLQDWTQEDERDKDAAKANLNYIGLDGNIGCLVNGAGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCMDAKINFDSNSAYRQKKIFDLQDWTQEDERDKDAAKANLNYIGLDGNIGCLVNGAGLA
220 230 240 250 260 270
330 340 350 360 370 380
pF1KB5 MATMDIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDKKVLAILVNIFGGIMRCDVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MATMDIIKLHGGTPANFLDVGGGATVHQVTEAFKLITSDKKVLAILVNIFGGIMRCDVIA
280 290 300 310 320 330
390 400 410 420 430 440
pF1KB5 QGIVMAVKDLEIKIPVVVRLQGTRVDDAKALIADSGLKILACDDLDEAARMVVKLSEIVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGIVMAVKDLEIKIPVVVRLQGTRVDDAKALIADSGLKILACDDLDEAARMVVKLSEIVT
340 350 360 370 380 390
450 460
pF1KB5 LAKQAHVDVKFQLPI
:::::::::::::::
XP_016 LAKQAHVDVKFQLPI
400
>>XP_016876296 (OMIM: 603921,612073) PREDICTED: succinyl (384 aa)
initn: 2396 init1: 2396 opt: 2396 Z-score: 2993.9 bits: 563.0 E(85289): 5.1e-160
Smith-Waterman score: 2396; 99.5% identity (100.0% similar) in 374 aa overlap (90-463:11-384)
60 70 80 90 100 110
pF1KB5 SMELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGV
.:::::::::::::::::::::::::::::
XP_016 MMNSMAERSVVGSKDVVIKAQVLAGGRGKGTFESGLKGGV
10 20 30 40
120 130 140 150 160 170
pF1KB5 KIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQG
50 60 70 80 90 100
180 190 200 210 220 230
pF1KB5 PVLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAEN
:::::::::::::::::::.::::::::::::::::::::::::::::::::::::::::
XP_016 PVLIGSSHGGVNIEDVAAESPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAEN
110 120 130 140 150 160
240 250 260 270 280 290
pF1KB5 MVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDE
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB5 RDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQVTE
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB5 AFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDAKAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDAKAL
290 300 310 320 330 340
420 430 440 450 460
pF1KB5 IADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
::::::::::::::::::::::::::::::::::::::::::::
XP_016 IADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
350 360 370 380
>>XP_016876298 (OMIM: 603921,612073) PREDICTED: succinyl (329 aa)
initn: 2122 init1: 2122 opt: 2122 Z-score: 2652.6 bits: 499.6 E(85289): 5.2e-141
Smith-Waterman score: 2122; 99.7% identity (100.0% similar) in 329 aa overlap (135-463:1-329)
110 120 130 140 150 160
pF1KB5 GRGKGTFESGLKGGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPR
::::::::::::::::::::::::::::::
XP_016 MIGKKLFTKQTGEKGRICNQVLVCERKYPR
10 20 30
170 180 190 200 210 220
pF1KB5 REYYFAITMERSFQGPVLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQ
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
XP_016 REYYFAITMERSFQGPVLIGSSHGGVNIEDVAAESPEAIIKEPIDIEEGIKKEQALQLAQ
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB5 KMGFPPNIVESAAENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMGFPPNIVESAAENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYR
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB5 QKKIFDLQDWTQEDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKKIFDLQDWTQEDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPAN
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB5 FLDVGGGATVHQVTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLDVGGGATVHQVTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPV
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB5 VVRLQGTRVDDAKALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVRLQGTRVDDAKALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
280 290 300 310 320
>>XP_016876297 (OMIM: 603921,612073) PREDICTED: succinyl (344 aa)
initn: 1709 init1: 1709 opt: 1709 Z-score: 2136.4 bits: 404.2 E(85289): 2.9e-112
Smith-Waterman score: 1709; 99.6% identity (100.0% similar) in 267 aa overlap (1-267:1-267)
10 20 30 40 50 60
pF1KB5 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGLFNNHGLQVQQQQQRNLSLHEYMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGLFNNHGLQVQQQQQRNLSLHEYMS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 MELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLKGGVK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 IVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERSFQGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 VLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAENM
::::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
XP_016 VLIGSSHGGVNIEDVAAESPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESAAENM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 VKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQEDER
:::::::::::::::::::::::::::
XP_016 VKLYSLFLKYDATMIEINPMVEDSDGAGPPGSHIELSCHIHLTWNRSGSLIYFLTLFFVV
250 260 270 280 290 300
>>NP_003839 (OMIM: 603922) succinate--CoA ligase [GDP-fo (432 aa)
initn: 1377 init1: 1354 opt: 1357 Z-score: 1695.0 bits: 322.8 E(85289): 1.1e-87
Smith-Waterman score: 1357; 52.0% identity (78.6% similar) in 425 aa overlap (21-441:4-426)
10 20 30 40 50
pF1KB5 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGL---FNNHGLQ-VQQQQQRNLSLH
: .:: :...: . .: : : : :: ..: :.:.
NP_003 MASPVAAQ--AGKLLRALALRPRFLAAGSQAVQLTSRRWLNLQ
10 20 30 40
60 70 80 90 100 110
pF1KB5 EYMSMELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLK
::.: .:... :: : . .:: . .:: ::.:..:..:.:::.::::::::.:.::::
NP_003 EYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLK
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB5 GGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERS
:::... .:. . ...:::: .: :::: ..: :.:.: : :: :.:: :.::
NP_003 GGVHLTKDPNVVGQLAKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB5 FQGPVLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESA
.::::.:: .:::.::.::: .:: :.:: ::: :::: :: ..:...:: . .:
NP_003 CNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIKDSQAQRMAENLGFVGPLKSQA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB5 AENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQ
:....:::.:::: :::..:.::. : .: :.:.:::::::.:. .::: :: ..: ..
NP_003 ADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB5 EDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQ
.. ...::: .:.::::::::.:.:::::::::: ::: :.:: ::::::.:::. :
NP_003 NEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQ
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB5 VTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDA
: .::::.:.: :: ::::::::::. : .::.::. : ..::.:.:.::::.:: :..:
NP_003 VYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTNVQEA
350 360 370 380 390 400
420 430 440 450 460
pF1KB5 KALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
. .. .::: : . ::..::. .:
NP_003 QKILNNSGLPITSAIDLEDAAKKAVASVAKK
410 420 430
>>XP_016862908 (OMIM: 603922) PREDICTED: succinyl-CoA li (433 aa)
initn: 1287 init1: 1287 opt: 1290 Z-score: 1611.3 bits: 307.3 E(85289): 5.2e-83
Smith-Waterman score: 1290; 53.2% identity (79.0% similar) in 395 aa overlap (21-411:4-396)
10 20 30 40 50
pF1KB5 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGL---FNNHGLQ-VQQQQQRNLSLH
: .:: :...: . .: : : : :: ..: :.:.
XP_016 MASPVAAQ--AGKLLRALALRPRFLAAGSQAVQLTSRRWLNLQ
10 20 30 40
60 70 80 90 100 110
pF1KB5 EYMSMELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLK
::.: .:... :: : . .:: . .:: ::.:..:..:.:::.::::::::.:.::::
XP_016 EYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLK
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB5 GGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERS
:::... .:. . ...:::: .: :::: ..: :.:.: : :: :.:: :.::
XP_016 GGVHLTKDPNVVGQLAKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB5 FQGPVLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESA
.::::.:: .:::.::.::: .:: :.:: ::: :::: :: ..:...:: . .:
XP_016 CNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIKDSQAQRMAENLGFVGPLKSQA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB5 AENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQ
:....:::.:::: :::..:.::. : .: :.:.:::::::.:. .::: :: ..: ..
XP_016 ADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB5 EDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQ
.. ...::: .:.::::::::.:.:::::::::: ::: :.:: ::::::.:::. :
XP_016 NEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQ
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB5 VTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDA
: .::::.:.: :: ::::::::::. : .::.::. : ..::.:.:.::::.::
XP_016 VYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTFMEKK
350 360 370 380 390 400
420 430 440 450 460
pF1KB5 KALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
XP_016 GSYMHIKQETGNSNENITGIQENVAHQNLRLN
410 420 430
>>NP_001171070 (OMIM: 603922) succinate--CoA ligase [GDP (440 aa)
initn: 1287 init1: 1287 opt: 1290 Z-score: 1611.2 bits: 307.3 E(85289): 5.3e-83
Smith-Waterman score: 1290; 53.2% identity (79.0% similar) in 395 aa overlap (21-411:4-396)
10 20 30 40 50
pF1KB5 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGL---FNNHGLQ-VQQQQQRNLSLH
: .:: :...: . .: : : : :: ..: :.:.
NP_001 MASPVAAQ--AGKLLRALALRPRFLAAGSQAVQLTSRRWLNLQ
10 20 30 40
60 70 80 90 100 110
pF1KB5 EYMSMELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLK
::.: .:... :: : . .:: . .:: ::.:..:..:.:::.::::::::.:.::::
NP_001 EYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLK
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB5 GGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERS
:::... .:. . ...:::: .: :::: ..: :.:.: : :: :.:: :.::
NP_001 GGVHLTKDPNVVGQLAKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB5 FQGPVLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESA
.::::.:: .:::.::.::: .:: :.:: ::: :::: :: ..:...:: . .:
NP_001 CNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIKDSQAQRMAENLGFVGPLKSQA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB5 AENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQ
:....:::.:::: :::..:.::. : .: :.:.:::::::.:. .::: :: ..: ..
NP_001 ADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB5 EDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQ
.. ...::: .:.::::::::.:.:::::::::: ::: :.:: ::::::.:::. :
NP_001 NEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQ
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB5 VTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDA
: .::::.:.: :: ::::::::::. : .::.::. : ..::.:.:.::::.::
NP_001 VYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTFMEKK
350 360 370 380 390 400
420 430 440 450 460
pF1KB5 KALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
NP_001 GSYMHIKQETGNSNENITGIQENVAHQNLSKCAISIFLC
410 420 430 440
>>XP_016862907 (OMIM: 603922) PREDICTED: succinyl-CoA li (445 aa)
initn: 1287 init1: 1287 opt: 1290 Z-score: 1611.1 bits: 307.3 E(85289): 5.3e-83
Smith-Waterman score: 1290; 53.2% identity (79.0% similar) in 395 aa overlap (21-411:4-396)
10 20 30 40 50
pF1KB5 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGL---FNNHGLQ-VQQQQQRNLSLH
: .:: :...: . .: : : : :: ..: :.:.
XP_016 MASPVAAQ--AGKLLRALALRPRFLAAGSQAVQLTSRRWLNLQ
10 20 30 40
60 70 80 90 100 110
pF1KB5 EYMSMELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLK
::.: .:... :: : . .:: . .:: ::.:..:..:.:::.::::::::.:.::::
XP_016 EYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLK
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB5 GGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERS
:::... .:. . ...:::: .: :::: ..: :.:.: : :: :.:: :.::
XP_016 GGVHLTKDPNVVGQLAKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB5 FQGPVLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESA
.::::.:: .:::.::.::: .:: :.:: ::: :::: :: ..:...:: . .:
XP_016 CNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIKDSQAQRMAENLGFVGPLKSQA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB5 AENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQ
:....:::.:::: :::..:.::. : .: :.:.:::::::.:. .::: :: ..: ..
XP_016 ADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB5 EDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQ
.. ...::: .:.::::::::.:.:::::::::: ::: :.:: ::::::.:::. :
XP_016 NEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQ
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB5 VTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDA
: .::::.:.: :: ::::::::::. : .::.::. : ..::.:.:.::::.::
XP_016 VYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTFMEKK
350 360 370 380 390 400
420 430 440 450 460
pF1KB5 KALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
XP_016 GSYMHIKQETGNSNENITGIQENVAHQNLIEKDIHIQTYGITGL
410 420 430 440
>>XP_016862906 (OMIM: 603922) PREDICTED: succinyl-CoA li (457 aa)
initn: 1287 init1: 1287 opt: 1290 Z-score: 1610.9 bits: 307.3 E(85289): 5.4e-83
Smith-Waterman score: 1290; 53.2% identity (79.0% similar) in 395 aa overlap (21-411:4-396)
10 20 30 40 50
pF1KB5 MAASMFYGRLVAVATLRNHRPRTAQRAAAQVLGSSGL---FNNHGLQ-VQQQQQRNLSLH
: .:: :...: . .: : : : :: ..: :.:.
XP_016 MASPVAAQ--AGKLLRALALRPRFLAAGSQAVQLTSRRWLNLQ
10 20 30 40
60 70 80 90 100 110
pF1KB5 EYMSMELLQEAGVSVPKGYVAKSPDEAYAIAKKLGSKDVVIKAQVLAGGRGKGTFESGLK
::.: .:... :: : . .:: . .:: ::.:..:..:.:::.::::::::.:.::::
XP_016 EYQSKKLMSDNGVRVQRFFVADTANEALEAAKRLNAKEIVLKAQILAGGRGKGVFNSGLK
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB5 GGVKIVFSPEEAKAVSSQMIGKKLFTKQTGEKGRICNQVLVCERKYPRREYYFAITMERS
:::... .:. . ...:::: .: :::: ..: :.:.: : :: :.:: :.::
XP_016 GGVHLTKDPNVVGQLAKQMIGYNLATKQTPKEGVKVNKVMVAEALDISRETYLAILMDRS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB5 FQGPVLIGSSHGGVNIEDVAAETPEAIIKEPIDIEEGIKKEQALQLAQKMGFPPNIVESA
.::::.:: .:::.::.::: .:: :.:: ::: :::: :: ..:...:: . .:
XP_016 CNGPVLVGSPQGGVDIEEVAASNPELIFKEQIDIFEGIKDSQAQRMAENLGFVGPLKSQA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB5 AENMVKLYSLFLKYDATMIEINPMVEDSDGAVLCMDAKINFDSNSAYRQKKIFDLQDWTQ
:....:::.:::: :::..:.::. : .: :.:.:::::::.:. .::: :: ..: ..
XP_016 ADQITKLYNLFLKIDATQVEVNPFGETPEGQVVCFDAKINFDDNAEFRQKDIFAMDDKSE
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB5 EDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLHGGTPANFLDVGGGATVHQ
.. ...::: .:.::::::::.:.:::::::::: ::: :.:: ::::::.:::. :
XP_016 NEPIENEAAKYDLKYIGLDGNIACFVNGAGLAMATCDIIFLNGGKPANFLDLGGGVKEAQ
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB5 VTEAFKLITSDKKVLAILVNIFGGIMRCDVIAQGIVMAVKDLEIKIPVVVRLQGTRVDDA
: .::::.:.: :: ::::::::::. : .::.::. : ..::.:.:.::::.::
XP_016 VYQAFKLLTADPKVEAILVNIFGGIVNCAIIANGITKACRELELKVPLVVRLEGTFMEKK
350 360 370 380 390 400
420 430 440 450 460
pF1KB5 KALIADSGLKILACDDLDEAARMVVKLSEIVTLAKQAHVDVKFQLPI
XP_016 GSYMHIKQETGNSNENITGIQENVAHQNLTCPHHLKPQPQLHLSNRYFQTLLEDKA
410 420 430 440 450
463 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 06:22:00 2016 done: Sat Nov 5 06:22:01 2016
Total Scan time: 9.050 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]