Result of FASTA (omim) for
pFN21AB4900
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4900, 542 aa
1>>>pF1KB4900 542 - 542 aa - 542 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2830+/-0.00053; mu= 18.1618+/- 0.033
mean_var=58.4146+/-12.135, 0's: 0 Z-trim(106.2): 53 B-trim: 0 in 0/49
Lambda= 0.167808
statistics sampled from 14269 (14316) to 14269 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.488), E-opt: 0.2 (0.168), width: 16
Scan time: 9.280
The best scores are: opt bits E(85289)
NP_004163 (OMIM: 600111,612656) excitatory amino a ( 542) 3412 835.2 0
XP_005248399 (OMIM: 600111,612656) PREDICTED: exci ( 542) 3412 835.2 0
NP_001276868 (OMIM: 600111,612656) excitatory amin ( 496) 2763 678.0 1.8e-194
XP_011512386 (OMIM: 600111,612656) PREDICTED: exci ( 435) 2739 672.2 9e-193
NP_001160167 (OMIM: 600111,612656) excitatory amin ( 497) 2707 664.5 2.2e-190
NP_004161 (OMIM: 133550,615232) excitatory amino a ( 524) 1702 421.2 4e-117
XP_011516310 (OMIM: 133550,615232) PREDICTED: exci ( 527) 1669 413.2 1e-114
XP_011516309 (OMIM: 133550,615232) PREDICTED: exci ( 547) 1669 413.2 1.1e-114
XP_016873627 (OMIM: 600300,617105) PREDICTED: exci ( 565) 1664 412.0 2.5e-114
NP_001239581 (OMIM: 600300,617105) excitatory amin ( 565) 1664 412.0 2.5e-114
NP_001182657 (OMIM: 600300,617105) excitatory amin ( 565) 1664 412.0 2.5e-114
XP_016873626 (OMIM: 600300,617105) PREDICTED: exci ( 565) 1664 412.0 2.5e-114
XP_011518587 (OMIM: 600300,617105) PREDICTED: exci ( 570) 1664 412.0 2.5e-114
XP_005253124 (OMIM: 600300,617105) PREDICTED: exci ( 571) 1664 412.0 2.5e-114
NP_004162 (OMIM: 600300,617105) excitatory amino a ( 574) 1664 412.0 2.5e-114
XP_016873625 (OMIM: 600300,617105) PREDICTED: exci ( 579) 1664 412.0 2.6e-114
XP_011516311 (OMIM: 133550,615232) PREDICTED: exci ( 504) 1662 411.5 3.2e-114
NP_001276869 (OMIM: 600111,612656) excitatory amin ( 430) 1605 397.7 3.9e-110
XP_011516312 (OMIM: 133550,615232) PREDICTED: exci ( 477) 1521 377.3 5.7e-104
XP_006722907 (OMIM: 600637) PREDICTED: excitatory ( 564) 1513 375.4 2.5e-103
XP_016882641 (OMIM: 600637) PREDICTED: excitatory ( 564) 1513 375.4 2.5e-103
NP_005062 (OMIM: 600637) excitatory amino acid tra ( 564) 1513 375.4 2.5e-103
XP_006722905 (OMIM: 600637) PREDICTED: excitatory ( 564) 1513 375.4 2.5e-103
NP_001274526 (OMIM: 604471) excitatory amino acid ( 472) 1226 305.9 1.8e-82
NP_006662 (OMIM: 604471) excitatory amino acid tra ( 560) 1220 304.5 5.7e-82
NP_003029 (OMIM: 600229,616657) neutral amino acid ( 532) 1041 261.1 6e-69
NP_005619 (OMIM: 109190) neutral amino acid transp ( 541) 1021 256.3 1.8e-67
NP_001138617 (OMIM: 109190) neutral amino acid tra ( 339) 1015 254.8 3.2e-67
XP_006712142 (OMIM: 600229,616657) PREDICTED: neut ( 312) 1004 252.1 1.9e-66
NP_001138616 (OMIM: 109190) neutral amino acid tra ( 313) 987 248.0 3.2e-65
XP_005259224 (OMIM: 109190) PREDICTED: neutral ami ( 469) 944 237.6 6.3e-62
XP_016870532 (OMIM: 133550,615232) PREDICTED: exci ( 488) 906 228.4 3.8e-59
XP_016870531 (OMIM: 133550,615232) PREDICTED: exci ( 511) 906 228.5 4e-59
NP_001259017 (OMIM: 600637) excitatory amino acid ( 312) 860 217.2 5.8e-56
NP_001259016 (OMIM: 600637) excitatory amino acid ( 312) 860 217.2 5.8e-56
XP_011540304 (OMIM: 604471) PREDICTED: excitatory ( 337) 743 188.9 2.1e-47
NP_001274524 (OMIM: 604471) excitatory amino acid ( 619) 743 189.0 3.6e-47
XP_016873628 (OMIM: 600300,617105) PREDICTED: exci ( 496) 694 177.1 1.1e-43
NP_001180422 (OMIM: 600229,616657) neutral amino a ( 234) 627 160.8 4.3e-39
NP_001274525 (OMIM: 604471) excitatory amino acid ( 158) 467 122.0 1.4e-27
NP_001160168 (OMIM: 600111,612656) excitatory amin ( 65) 380 100.8 1.4e-21
>>NP_004163 (OMIM: 600111,612656) excitatory amino acid (542 aa)
initn: 3412 init1: 3412 opt: 3412 Z-score: 4460.9 bits: 835.2 E(85289): 0
Smith-Waterman score: 3412; 100.0% identity (100.0% similar) in 542 aa overlap (1-542:1-542)
10 20 30 40 50 60
pF1KB4 MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 NLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 VNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 IVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 GTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 TTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSET
490 500 510 520 530 540
pF1KB4 KM
::
NP_004 KM
>>XP_005248399 (OMIM: 600111,612656) PREDICTED: excitato (542 aa)
initn: 3412 init1: 3412 opt: 3412 Z-score: 4460.9 bits: 835.2 E(85289): 0
Smith-Waterman score: 3412; 100.0% identity (100.0% similar) in 542 aa overlap (1-542:1-542)
10 20 30 40 50 60
pF1KB4 MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 NLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 VNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 IVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 GTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRT
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 TTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSET
490 500 510 520 530 540
pF1KB4 KM
::
XP_005 KM
>>NP_001276868 (OMIM: 600111,612656) excitatory amino ac (496 aa)
initn: 2763 init1: 2763 opt: 2763 Z-score: 3612.4 bits: 678.0 E(85289): 1.8e-194
Smith-Waterman score: 3017; 91.5% identity (91.5% similar) in 542 aa overlap (1-542:1-496)
10 20 30 40 50 60
pF1KB4 MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMG
: :::::::::::::
NP_001 G----------------------------------------------MAALDSKASGKMG
70
130 140 150 160 170 180
pF1KB4 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPP
80 90 100 110 120 130
190 200 210 220 230 240
pF1KB4 NLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNG
140 150 160 170 180 190
250 260 270 280 290 300
pF1KB4 VNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGK
200 210 220 230 240 250
310 320 330 340 350 360
pF1KB4 IVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITAL
260 270 280 290 300 310
370 380 390 400 410 420
pF1KB4 GTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFE
320 330 340 350 360 370
430 440 450 460 470 480
pF1KB4 LNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRT
380 390 400 410 420 430
490 500 510 520 530 540
pF1KB4 TTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSET
440 450 460 470 480 490
pF1KB4 KM
::
NP_001 KM
>>XP_011512386 (OMIM: 600111,612656) PREDICTED: excitato (435 aa)
initn: 2739 init1: 2739 opt: 2739 Z-score: 3581.9 bits: 672.2 E(85289): 9e-193
Smith-Waterman score: 2739; 100.0% identity (100.0% similar) in 435 aa overlap (108-542:1-435)
80 90 100 110 120 130
pF1KB4 VKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVI
::::::::::::::::::::::::::::::
XP_011 MAALDSKASGKMGMRAVVYYMTTTIIAVVI
10 20 30
140 150 160 170 180 190
pF1KB4 GIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKR
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB4 SFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSMCFGFVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSMCFGFVI
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB4 GNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIGGQLAMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIGGQLAMY
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB4 TVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLE
220 230 240 250 260 270
380 390 400 410 420 430
pF1KB4 ENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAAS
280 290 300 310 320 330
440 450 460 470 480 490
pF1KB4 IGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHL
340 350 360 370 380 390
500 510 520 530 540
pF1KB4 SRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSETKM
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSETKM
400 410 420 430
>>NP_001160167 (OMIM: 600111,612656) excitatory amino ac (497 aa)
initn: 3120 init1: 2707 opt: 2707 Z-score: 3539.1 bits: 664.5 E(85289): 2.2e-190
Smith-Waterman score: 3033; 91.5% identity (91.5% similar) in 542 aa overlap (1-542:1-497)
10 20 30 40 50 60
pF1KB4 MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTKSNGEEPKMGGRMERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 GTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTILGFTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRAVVYYMTTTIIAVVIGIIIVIIIHPGKGTKENMHREGKIVRVTAADAFLDLIRNMFPP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 NLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLVEACFKQFKTNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 VNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNALGLVVFSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 IVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVEMEDMGVIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 GTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTSSSSATLPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LNFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRT
::::::::: :::::
NP_001 LNFGQIITIR---------------------------------------------DRLRT
430
490 500 510 520 530 540
pF1KB4 TTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTNVLGDSLGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSET
440 450 460 470 480 490
pF1KB4 KM
::
NP_001 KM
>>NP_004161 (OMIM: 133550,615232) excitatory amino acid (524 aa)
initn: 1656 init1: 916 opt: 1702 Z-score: 2223.8 bits: 421.2 E(85289): 4e-117
Smith-Waterman score: 1702; 55.2% identity (82.2% similar) in 493 aa overlap (45-534:14-501)
20 30 40 50 60 70
pF1KB4 MERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLL-TVTAVIVGTILGFTLRPYR-
...: .::: ::.::..: : .: .
NP_004 MGKPARKGCEWKRFLKNNWVLLSTVAAVVLGITTGVLVREHSN
10 20 30 40
80 90 100 110 120 130
pF1KB4 MSYREVKYFSFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTI
.: : ::.::::.:::::....:::::::..::.:::::..:::.:.::::::. ::.
NP_004 LSTLEKFYFAFPGEILMRMLKLIILPLIISSMITGVAALDSNVSGKIGLRAVVYYFCTTL
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB4 IAVVIGIIIVIIIHPGKGTKEN-MHREGKIVRVTAADAFLDLIRNMFPPNLVEACFKQFK
:::..::..:. :.:: : . . : :. .:...::.::::::::: :::.:::.:.:
NP_004 IAVILGIVLVVSIKPGVTQKVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQACFQQYK
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB4 TNYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSM
:. :. : : . . ... .. : . . .. :.: : .:.:.:::.:: .
NP_004 TKREE--VKPPSDPEMNMTEESFTAVMTTAISKNK-TKEYKIVGMYSDGINVLGLIVFCL
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB4 CFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIG
::.:::.: :.:: : .::..:..: :..: .:: : :.::::::::::.:.:: ..
NP_004 VFGLVIGKMGEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFR
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB4 GQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPI
.:..: .::..:: ::....:::.::.:.::::. : :. :::.::: ::::::::.
NP_004 -KLGLYMATVLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPV
290 300 310 320 330
380 390 400 410 420 430
pF1KB4 TFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISI
::.: :::: ::::.:::::::::::::::::::::.::.::::.:...:..::::::::
NP_004 TFRCAEENNQVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISI
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB4 TATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGA
:::.:::::::.::::::::::::..::::..:.::::::::.:::.:: .:::::..:.
NP_004 TATSASIGAAGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGT
400 410 420 430 440 450
500 510 520 530 540
pF1KB4 GIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSETKM
::::.::..::.. :: .... ... : .:..:.:
NP_004 GIVEKLSKKELEQMDVSSEVNIVNPFALESTI-LDNEDSDTKKSYVNGGFAVDKSDTISF
460 470 480 490 500 510
NP_004 TQTSQF
520
>>XP_011516310 (OMIM: 133550,615232) PREDICTED: excitato (527 aa)
initn: 1656 init1: 916 opt: 1669 Z-score: 2180.5 bits: 413.2 E(85289): 1e-114
Smith-Waterman score: 1669; 55.0% identity (81.8% similar) in 484 aa overlap (53-534:26-504)
30 40 50 60 70 80
pF1KB4 RKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILGFTLRPYR-MSYREVKYF
:. ..: .: : .: . .: : ::
XP_011 MTARRKFACRDCKPHGDPDHMSSTELSKVVVCTGITTGVLVREHSNLSTLEKFYF
10 20 30 40 50
90 100 110 120 130 140
pF1KB4 SFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIII
.::::.:::::....:::::::..::.:::::..:::.:.::::::. ::.:::..::..
XP_011 AFPGEILMRMLKLIILPLIISSMITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVL
60 70 80 90 100 110
150 160 170 180 190 200
pF1KB4 VIIIHPGKGTKEN-MHREGKIVRVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRSFK
:. :.:: : . . : :. .:...::.::::::::: :::.:::.:.::. :. :
XP_011 VVSIKPGVTQKVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTKREE--VK
120 130 140 150 160 170
210 220 230 240 250 260
pF1KB4 VPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSMCFGFVIGNM
: . . ... .. : . . .. :.: : .:.:.:::.:: . ::.:::.:
XP_011 PPSDPEMNMTEESFTAVMTTAISKNK-TKEYKIVGMYSDGINVLGLIVFCLVFGLVIGKM
180 190 200 210 220 230
270 280 290 300 310 320
pF1KB4 KEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIGGQLAMYTVT
:.:: : .::..:..: :..: .:: : :.::::::::::.:.:: .. .:..: .:
XP_011 GEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFR-KLGLYMAT
240 250 260 270 280 290
330 340 350 360 370 380
pF1KB4 VIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENN
:..:: ::....:::.::.:.::::. : :. :::.::: ::::::::.::.: ::::
XP_011 VLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENN
300 310 320 330 340 350
390 400 410 420 430 440
pF1KB4 GVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGA
::::.:::::::::::::::::::::.::.::::.:...:..:::::::::::.:::::
XP_011 QVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGA
360 370 380 390 400 410
450 460 470 480 490 500
pF1KB4 AGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRH
::.::::::::::::..::::..:.::::::::.:::.:: .:::::..:.::::.::..
XP_011 AGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK
420 430 440 450 460 470
510 520 530 540
pF1KB4 ELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSETKM
::.. :: .... ... : .:..:.:
XP_011 ELEQMDVSSEVNIVNPFALESTI-LDNEDSDTKKSYVNGGFAVDKSDTISFTQTSQF
480 490 500 510 520
>>XP_011516309 (OMIM: 133550,615232) PREDICTED: excitato (547 aa)
initn: 1656 init1: 916 opt: 1669 Z-score: 2180.3 bits: 413.2 E(85289): 1.1e-114
Smith-Waterman score: 1669; 55.0% identity (81.8% similar) in 484 aa overlap (53-534:46-524)
30 40 50 60 70 80
pF1KB4 RKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILGFTLRPYR-MSYREVKYF
:. ..: .: : .: . .: : ::
XP_011 KNNWVLLSTVAAVVLDCKPHGDPDHMSSTELSKVVVCTGITTGVLVREHSNLSTLEKFYF
20 30 40 50 60 70
90 100 110 120 130 140
pF1KB4 SFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTIIAVVIGIII
.::::.:::::....:::::::..::.:::::..:::.:.::::::. ::.:::..::..
XP_011 AFPGEILMRMLKLIILPLIISSMITGVAALDSNVSGKIGLRAVVYYFCTTLIAVILGIVL
80 90 100 110 120 130
150 160 170 180 190 200
pF1KB4 VIIIHPGKGTKEN-MHREGKIVRVTAADAFLDLIRNMFPPNLVEACFKQFKTNYEKRSFK
:. :.:: : . . : :. .:...::.::::::::: :::.:::.:.::. :. :
XP_011 VVSIKPGVTQKVGEIARTGSTPEVSTVDAMLDLIRNMFPENLVQACFQQYKTKREE--VK
140 150 160 170 180 190
210 220 230 240 250 260
pF1KB4 VPIQANETLVGAVINNVSEAMETLTRITEELVPVPGSVNGVNALGLVVFSMCFGFVIGNM
: . . ... .. : . . .. :.: : .:.:.:::.:: . ::.:::.:
XP_011 PPSDPEMNMTEESFTAVMTTAISKNK-TKEYKIVGMYSDGINVLGLIVFCLVFGLVIGKM
200 210 220 230 240 250
270 280 290 300 310 320
pF1KB4 KEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMGVIGGQLAMYTVT
:.:: : .::..:..: :..: .:: : :.::::::::::.:.:: .. .:..: .:
XP_011 GEKGQILVDFFNALSDATMKIVQIIMCYMPLGILFLIAGKIIEVEDWEIFR-KLGLYMAT
260 270 280 290 300 310
330 340 350 360 370 380
pF1KB4 VIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSATLPITFKCLEENN
:..:: ::....:::.::.:.::::. : :. :::.::: ::::::::.::.: ::::
XP_011 VLTGLAIHSIVILPLIYFIVVRKNPFRFAMGMAQALLTALMISSSSATLPVTFRCAEENN
320 330 340 350 360 370
390 400 410 420 430 440
pF1KB4 GVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIITISITATAASIGA
::::.:::::::::::::::::::::.::.::::.:...:..:::::::::::.:::::
XP_011 QVDKRITRFVLPVGATINMDGTALYEAVAAVFIAQLNDLDLGIGQIITISITATSASIGA
380 390 400 410 420 430
450 460 470 480 490 500
pF1KB4 AGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRH
::.::::::::::::..::::..:.::::::::.:::.:: .:::::..:.::::.::..
XP_011 AGVPQAGLVTMVIVLSAVGLPAEDVTLIIAVDWLLDRFRTMVNVLGDAFGTGIVEKLSKK
440 450 460 470 480 490
510 520 530 540
pF1KB4 ELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSETKM
::.. :: .... ... : .:..:.:
XP_011 ELEQMDVSSEVNIVNPFALESTI-LDNEDSDTKKSYVNGGFAVDKSDTISFTQTSQF
500 510 520 530 540
>>XP_016873627 (OMIM: 600300,617105) PREDICTED: excitato (565 aa)
initn: 1514 init1: 1149 opt: 1664 Z-score: 2173.5 bits: 412.0 E(85289): 2.5e-114
Smith-Waterman score: 1664; 54.4% identity (80.4% similar) in 500 aa overlap (45-538:32-525)
20 30 40 50 60 70
pF1KB4 MERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILGFTLRPYRMS
: .: .. ::: .::.:.. : ::
XP_016 PKQVEVRMHDSHLGSEEPKHRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPI
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB4 YREVKYF-SFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTII
. .: .. .:::..:::::.::.::::::::.::...::.::::..: ::.::::.::::
XP_016 HPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTII
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB4 AVVIGIIIVIIIHPGKGTKENMHREGKIV-RVTAADAFLDLIRNMFPPNLVEACFKQFKT
:.:.:.:.:. ::::. ... :: .:.. :::::::::.:: :::.:::.:..:
XP_016 AAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQT
130 140 150 160 170 180
200 210 220 230 240
pF1KB4 NYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEE--LVPVPGSV--NGVNALGLVV
.: : . . . ..:: :: ::.:.. :: .: : .:.:.:::.
XP_016 VTKKVLVAPPPDEEANATSAV---VSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIG
190 200 210 220 230
250 260 270 280 290 300
pF1KB4 FSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMG
: . ::...:.: .:.. . .::. ::: .:.:: .::::.:.:: :: :::. ..:.
XP_016 FFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB4 VIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSAT
:.. ::.:: ::::.::.::. : :::.::.::::::. :..:..:: ::::::.::..:
XP_016 VVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB4 LPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIIT
::.::.::::: :.:::::::::::::::::::::::::.:::::::.:. :. :::.:
XP_016 LPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVT
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB4 ISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDS
.:.::: ::.:::.::.::::::...::.:::::.::.:..::::.:::.::..::.:::
XP_016 VSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDS
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB4 LGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSETKM
.::::: :::. :: . : . . : :. :: : : : .: .... .:
XP_016 FGAGIVYHLSKSELDTIDSQ--HRVHEDIEMTKT-QSIYDDMKNHRESNSNQCVYAAHNS
480 490 500 510 520 530
XP_016 VIVDECKVTLAANGKSADCSVEEEPWKREK
540 550 560
>>NP_001239581 (OMIM: 600300,617105) excitatory amino ac (565 aa)
initn: 1514 init1: 1149 opt: 1664 Z-score: 2173.5 bits: 412.0 E(85289): 2.5e-114
Smith-Waterman score: 1664; 54.4% identity (80.4% similar) in 500 aa overlap (45-538:32-525)
20 30 40 50 60 70
pF1KB4 MERFQQGVRKRTLLAKKKVQNITKEDVKSYLFRNAFVLLTVTAVIVGTILGFTLRPYRMS
: .: .. ::: .::.:.. : ::
NP_001 PKQVEVRMHDSHLGSEEPKHRHLGLRLCDKLGKNLLLTLTVFGVILGAVCGGLLRLASPI
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB4 YREVKYF-SFPGELLMRMLQMLVLPLIISSLVTGMAALDSKASGKMGMRAVVYYMTTTII
. .: .. .:::..:::::.::.::::::::.::...::.::::..: ::.::::.::::
NP_001 HPDVVMLIAFPGDILMRMLKMLILPLIISSLITGLSGLDAKASGRLGTRAMVYYMSTTII
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB4 AVVIGIIIVIIIHPGKGTKENMHREGKIV-RVTAADAFLDLIRNMFPPNLVEACFKQFKT
:.:.:.:.:. ::::. ... :: .:.. :::::::::.:: :::.:::.:..:
NP_001 AAVLGVILVLAIHPGNPKLKKQLGPGKKNDEVSSLDAFLDLIRNLFPENLVQACFQQIQT
130 140 150 160 170 180
200 210 220 230 240
pF1KB4 NYEKRSFKVPIQANETLVGAVINNVSEAMETLTRITEE--LVPVPGSV--NGVNALGLVV
.: : . . . ..:: :: ::.:.. :: .: : .:.:.:::.
NP_001 VTKKVLVAPPPDEEANATSAV---VSLLNETVTEVPEETKMVIKKGLEFKDGMNVLGLIG
190 200 210 220 230
250 260 270 280 290 300
pF1KB4 FSMCFGFVIGNMKEQGQALREFFDSLNEAIMRLVAVIMWYAPVGILFLIAGKIVEMEDMG
: . ::...:.: .:.. . .::. ::: .:.:: .::::.:.:: :: :::. ..:.
NP_001 FFIAFGIAMGKMGDQAKLMVDFFNILNEIVMKLVIMIMWYSPLGIACLICGKIIAIKDLE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB4 VIGGQLAMYTVTVIVGLLIHAVIVLPLLYFLVTRKNPWVFIGGLLQALITALGTSSSSAT
:.. ::.:: ::::.::.::. : :::.::.::::::. :..:..:: ::::::.::..:
NP_001 VVARQLGMYMVTVIIGLIIHGGIFLPLIYFVVTRKNPFSFFAGIFQAWITALGTASSAGT
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB4 LPITFKCLEENNGVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNFELNFGQIIT
::.::.::::: :.:::::::::::::::::::::::::.:::::::.:. :. :::.:
NP_001 LPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGVVLDGGQIVT
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB4 ISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDS
.:.::: ::.:::.::.::::::...::.:::::.::.:..::::.:::.::..::.:::
NP_001 VSLTATLASVGAASIPSAGLVTMLLILTAVGLPTEDISLLVAVDWLLDRMRTSVNVVGDS
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB4 LGAGIVEHLSRHELKNRDVEMGNSVIEENEMKKPYQLIAQDNETEKPIDSETKM
.::::: :::. :: . : . . : :. :: : : : .: .... .:
NP_001 FGAGIVYHLSKSELDTIDSQ--HRVHEDIEMTKT-QSIYDDMKNHRESNSNQCVYAAHNS
480 490 500 510 520 530
NP_001 VIVDECKVTLAANGKSADCSVEEEPWKREK
540 550 560
542 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 06:05:59 2016 done: Sat Nov 5 06:06:01 2016
Total Scan time: 9.280 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]