Result of FASTA (omim) for
pFN21AE3692
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3692, 182 aa
1>>>pF1KE3692 182 - 182 aa - 182 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7066+/-0.000254; mu= 12.7883+/- 0.016
mean_var=90.1609+/-17.874, 0's: 0 Z-trim(122.5): 7 B-trim: 33 in 1/53
Lambda= 0.135072
statistics sampled from 40730 (40737) to 40730 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.804), E-opt: 0.2 (0.478), width: 16
Scan time: 5.230
The best scores are: opt bits E(85289)
NP_036360 (OMIM: 613782) methionine-R-sulfoxide re ( 182) 1286 259.2 2.6e-69
XP_011517728 (OMIM: 613782) PREDICTED: methionine- ( 141) 704 145.7 2.9e-35
NP_932346 (OMIM: 613718,613719) methionine-R-sulfo ( 192) 468 99.9 2.6e-21
NP_001026849 (OMIM: 613718,613719) methionine-R-su ( 185) 466 99.4 3.3e-21
NP_001180390 (OMIM: 613718,613719) methionine-R-su ( 185) 466 99.4 3.3e-21
NP_001180389 (OMIM: 613718,613719) methionine-R-su ( 185) 466 99.4 3.3e-21
NP_057416 (OMIM: 606216) methionine-R-sulfoxide re ( 116) 233 53.9 1.1e-07
>>NP_036360 (OMIM: 613782) methionine-R-sulfoxide reduct (182 aa)
initn: 1286 init1: 1286 opt: 1286 Z-score: 1365.4 bits: 259.2 E(85289): 2.6e-69
Smith-Waterman score: 1286; 100.0% identity (100.0% similar) in 182 aa overlap (1-182:1-182)
10 20 30 40 50 60
pF1KE3 MARLLWLLRGLTLGTAPRRAVRGQAGGGGPGTGPGLGEAGSLATCELPLAKSEWQKKLTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MARLLWLLRGLTLGTAPRRAVRGQAGGGGPGTGPGLGEAGSLATCELPLAKSEWQKKLTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 EQFYVTREKGTEPPFSGIYLNNKEAGMYHCVCCDSPLFSSEKKYCSGTGWPSFSEAHGTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EQFYVTREKGTEPPFSGIYLNNKEAGMYHCVCCDSPLFSSEKKYCSGTGWPSFSEAHGTS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GSDESHTGILRRLDTSLGSARTEVVCKQCEAHLGHVFPDGPGPNGQRFCINSVALKFKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GSDESHTGILRRLDTSLGSARTEVVCKQCEAHLGHVFPDGPGPNGQRFCINSVALKFKPR
130 140 150 160 170 180
pF1KE3 KH
::
NP_036 KH
>>XP_011517728 (OMIM: 613782) PREDICTED: methionine-R-su (141 aa)
initn: 695 init1: 695 opt: 704 Z-score: 754.0 bits: 145.7 E(85289): 2.9e-35
Smith-Waterman score: 704; 85.5% identity (90.3% similar) in 124 aa overlap (1-118:1-124)
10 20 30 40 50 60
pF1KE3 MARLLWLLRGLTLGTAPRRAVRGQAGGGGPGTGPGLGEAGSLATCELPLAKSEWQKKLTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MARLLWLLRGLTLGTAPRRAVRGQAGGGGPGTGPGLGEAGSLATCELPLAKSEWQKKLTP
10 20 30 40 50 60
70 80 90 100 110
pF1KE3 EQFYVTREKGTEPPFSGIYLNNKEAGMYHCVCCDSPLFSS----EKKYCS--GTGWPSFS
:::::::::::::::::::::::::::::::::::::: : .:. : :. :: :
XP_011 EQFYVTREKGTEPPFSGIYLNNKEAGMYHCVCCDSPLFRSLLDIQKEVFSIKGSRSPSTS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 EAHGTSGSDESHTGILRRLDTSLGSARTEVVCKQCEAHLGHVFPDGPGPNGQRFCINSVA
...:
XP_011 RGNGFDSEGAVRTIPGGLTVE
130 140
>>NP_932346 (OMIM: 613718,613719) methionine-R-sulfoxide (192 aa)
initn: 434 init1: 247 opt: 468 Z-score: 503.6 bits: 99.9 E(85289): 2.6e-21
Smith-Waterman score: 468; 47.3% identity (72.3% similar) in 148 aa overlap (35-179:28-168)
10 20 30 40 50 60
pF1KE3 LWLLRGLTLGTAPRRAVRGQAGGGGPGTGPGLGEAGSL---ATCELPLAKSEWQKKLTPE
: ...:: .:.. ....: .:.:::
NP_932 MSPRRTLPRPLSLCLSLCLCLCLAAALGSAQSGSCRDKKNCKVVFSQQELRKRLTPL
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 QFYVTREKGTEPPFSGIYLNNKEAGMYHCVCCDSPLFSSEKKYCSGTGWPSFSEAHGTSG
:..::.::::: : : : ..:. :.:.:: : .:::.:: :. ::.::::: : . .
NP_932 QYHVTQEKGTESAFEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPSF---HDVIN
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 SDESHTGILRRLDTSLGSARTEVVCKQCEAHLGHVFPDGPGPNGQRFCINSVALKFKPRK
:. .: : : : :.:. :.:: :::::.: ::: :.:.:.::::.::.: :
NP_932 SE----AITFTDDFSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSAALSFTPAD
120 130 140 150 160 170
pF1KE3 H
NP_932 SSGTAEGGSGVASPAQADKAEL
180 190
>>NP_001026849 (OMIM: 613718,613719) methionine-R-sulfox (185 aa)
initn: 434 init1: 247 opt: 466 Z-score: 501.7 bits: 99.4 E(85289): 3.3e-21
Smith-Waterman score: 466; 49.6% identity (74.1% similar) in 135 aa overlap (45-179:34-161)
20 30 40 50 60 70
pF1KE3 TAPRRAVRGQAGGGGPGTGPGLGEAGSLATCELPLAKSEWQKKLTPEQFYVTREKGTEPP
:.. ....: .:.::: :..::.:::::
NP_001 FNLLHLVTKSQPVALRACGLPSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGTESA
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE3 FSGIYLNNKEAGMYHCVCCDSPLFSSEKKYCSGTGWPSFSEAHGTSGSDESHTGILRRLD
: : : ..:. :.:.:: : .:::.:: :. ::.::::: : . .:. .: :
NP_001 FEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPSF---HDVINSE----AITFTDD
70 80 90 100 110
140 150 160 170 180
pF1KE3 TSLGSARTEVVCKQCEAHLGHVFPDGPGPNGQRFCINSVALKFKPRKH
: : :.:. :.:: :::::.: ::: :.:.:.::::.::.: :
NP_001 FSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSAALSFTPADSSGTAEGGSGVAS
120 130 140 150 160 170
NP_001 PAQADKAEL
180
>>NP_001180390 (OMIM: 613718,613719) methionine-R-sulfox (185 aa)
initn: 434 init1: 247 opt: 466 Z-score: 501.7 bits: 99.4 E(85289): 3.3e-21
Smith-Waterman score: 466; 49.6% identity (74.1% similar) in 135 aa overlap (45-179:34-161)
20 30 40 50 60 70
pF1KE3 TAPRRAVRGQAGGGGPGTGPGLGEAGSLATCELPLAKSEWQKKLTPEQFYVTREKGTEPP
:.. ....: .:.::: :..::.:::::
NP_001 FNLLHLVTKSQPVALRACGLPSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGTESA
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE3 FSGIYLNNKEAGMYHCVCCDSPLFSSEKKYCSGTGWPSFSEAHGTSGSDESHTGILRRLD
: : : ..:. :.:.:: : .:::.:: :. ::.::::: : . .:. .: :
NP_001 FEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPSF---HDVINSE----AITFTDD
70 80 90 100 110
140 150 160 170 180
pF1KE3 TSLGSARTEVVCKQCEAHLGHVFPDGPGPNGQRFCINSVALKFKPRKH
: : :.:. :.:: :::::.: ::: :.:.:.::::.::.: :
NP_001 FSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSAALSFTPADSSGTAEGGSGVAS
120 130 140 150 160 170
NP_001 PAQADKAEL
180
>>NP_001180389 (OMIM: 613718,613719) methionine-R-sulfox (185 aa)
initn: 434 init1: 247 opt: 466 Z-score: 501.7 bits: 99.4 E(85289): 3.3e-21
Smith-Waterman score: 466; 49.6% identity (74.1% similar) in 135 aa overlap (45-179:34-161)
20 30 40 50 60 70
pF1KE3 TAPRRAVRGQAGGGGPGTGPGLGEAGSLATCELPLAKSEWQKKLTPEQFYVTREKGTEPP
:.. ....: .:.::: :..::.:::::
NP_001 FNLLHLVTKSQPVALRACGLPSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGTESA
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE3 FSGIYLNNKEAGMYHCVCCDSPLFSSEKKYCSGTGWPSFSEAHGTSGSDESHTGILRRLD
: : : ..:. :.:.:: : .:::.:: :. ::.::::: : . .:. .: :
NP_001 FEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPSF---HDVINSE----AITFTDD
70 80 90 100 110
140 150 160 170 180
pF1KE3 TSLGSARTEVVCKQCEAHLGHVFPDGPGPNGQRFCINSVALKFKPRKH
: : :.:. :.:: :::::.: ::: :.:.:.::::.::.: :
NP_001 FSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSAALSFTPADSSGTAEGGSGVAS
120 130 140 150 160 170
NP_001 PAQADKAEL
180
>>NP_057416 (OMIM: 606216) methionine-R-sulfoxide reduct (116 aa)
initn: 176 init1: 94 opt: 233 Z-score: 259.1 bits: 53.9 E(85289): 1.1e-07
Smith-Waterman score: 233; 38.5% identity (61.5% similar) in 109 aa overlap (75-180:7-106)
50 60 70 80 90 100
pF1KE3 CELPLAKSEWQKKLTPEQFYVTREKGTEPPFSG-IYLNNKEAGMYHCVCCDSPLFSSEKK
:.: .. :. : :.: :. : ::::..:
NP_057 MSFCSFFGGEVFQNHFEPGVYVCAKCGYELFSSRSK
10 20 30
110 120 130 140 150 160
pF1KE3 YCSGTGWPSFSEA-HGTSGSDESHTGILRRLDTSLGSARTEVVCKQCEAHLGHVF-PDGP
: .. ::.:.:. :. : . .: . . . : .: : .: ::: : :::
NP_057 YAHSSPWPAFTETIHADS--------VAKRPEHNRSEA-LKVSCGKCGNGLGHEFLNDGP
40 50 60 70 80
170 180
pF1KE3 GPNGQRFCINSVALKFKPRKH
:. .:::: : .::: :.
NP_057 KPGQSRFCIFSSSLKFVPKGKETSASQGH
90 100 110
182 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 22:50:42 2016 done: Sat Nov 5 22:50:43 2016
Total Scan time: 5.230 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]